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@@ -4,112 +4,92 @@
- Registrant: SYNGENTA CROP PROTECTION, LLC
- Signal word: Caution
- Active ingredients: Thiamethoxam (20%); Fludioxonil (1%); Metalaxyl-M (5.99%); Sedaxane (1%)
- Label accepted: 2019-09-20
- Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000100-01459-20190920.pdf
- Label accepted: 2026-06-22
- Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000100-01459-20260622.pdf
---
UNITED STATES ENVIRONMENTAL PROTECTION AGENCY
WASHINGTON, DC 20460
Reg Review Label Acceptable v.20151230
OFFICE OF CHEMICAL SAFETY
AND POLLUTION PREVENTION
September 20, 2019
Ricky Kyaw
Regulatory Product Manager
Syngenta Crop Protection, LLC
PO Box 18300
Greensboro, NC 27419
Subject: Registration Review Label Mitigation for Fludioxonil and Mefenoxam
Product Name: SYT0113
EPA Registration Number: 100-1459
Application Date: February 1, 2019
Decision Number: 554957; 554958
Dear Mr. Kyaw:
The Agency, in accordance with the Federal Insecticide, Fungicide and Rodenticide Act
(FIFRA), as amended, has completed reviewing all of the information submitted with your
application to support the Registration Review of the above referenced product in connection
with the Fludioxonil and Mefenoxam Interim Decisions, and has concluded that your submission
June 22, 2026
Patsy Laird
Regulatory Manager, Seedcare
Syngenta Crop Protection, LLC
P.O. Box 18300
Greensboro, NC 27419
Subject: Label Amendment - Registrat ion Review Mitigation for Sedaxane
Product Name: SYT0113
EPA Registration Number: 100-1459
Application Date: February 13, 2026
Case Number: 684857
Dear Mrs. Patsy Laird:
The Agency, in accordance with the Federal Insecticide, Fungicide, and Rodenticide Act
(FIFRA), as amended, has completed reviewing all the information submitted with your
application to support the Registration Review of the above referenced product in
connection with the Sedaxane Interim Decision, and has concluded that your submission
is acceptable. The label referred to above, submitted in connection with registration under
FIFRA, as amended, is acceptable.
Should you wish to add/retain a reference to the company’s website on your label, then please be
aware that the website becomes labeling under the Federal Insecticide Fungicide and Rodenticide
Act and is subject to review by the Agency. If the website is false or misleading, the product
would be misbranded and unlawful to sell or distribute under FIFRA section 12(a)(1)(E). 40
CFR 156.10(a)(5) list examples of statements EPA may consider false or misleading. In addition,
regardless of whether a website is referenced on your product’s label, claims made on the
website may not substantially differ from those claims approved through the registration process.
Therefore, should the Agency find or if it is brought to our attention that a website contains false
or misleading statements or claims substantially differing from the EPA approved registration,
the website will be referred to the EPA’s Office of Enforcement and Compliance.
A copy of your label stamped “Accepted” is enclosed. Products shipped after 12 months from the
date of this amendment must bear the new revised label. Your release for shipment of the
product bearing the amended label constitutes acceptance of these conditions. If these conditions
are not complied with, the registration will be subject to cancellation in accordance with FIFRA
section 6.
FIFRA, as amended, is acceptable.
Should you wish to add/retain a reference to the company’s website on your label, then
please be aware that the website becomes labeling under the Federal Insecticide,
Fungicide, and Rodenticide Act and is subject to review by the Agency. If the website is
false or misleading, the product would be misbranded and unlawful to sell or distribute
under FIFRA section 12(a)(1)(E). 40 CFR 156.10(a)(5) list examples of statements EPA may
consider false or misleading. In addition, regardless of whether a website is referenced on
your product’s label, claims made on the website may not substantially differ from those
claims approved through the registration process. Therefore, should the Agency find or if it
is brought to our attention that a website contains false or misleading statements or
claims substantially differing from the EPA approved registration, the website will be
referred to the EPA’s Office of Enforcement and Compliance Assurance.
Page 2 of 2
EPA Reg. No. 100-1459
Decision No. 554957; 554958
Decision No. 684857
A stamped copy of your labeling is enclosed for your records. This labeling
supersedes all previously accepted labeling and must be used at your next label
printing. You must submit one copy of the final printed labeling before you release
the product for shipment with the new labeling. In accordance with 40 CFR
152.130(c), you may distribute or sell this product under the previously approved
labeling for 12 months from the date of this letter. After 12 months, you may only
distribute or sell this product if it bears this new revised labeling or subsequently
approved labeling. “To distribute or sell” is defined under FIFRA section 2(gg) and
its implementing regulation at 40 CFR 152.3.
If you have any questions about this letter, please contact Samantha Carter by phone at
202-566-1179, or via email at carter.samantha@epa.gov.
Sincerely,
Jaclyn Pyne, Team Leader
Risk Management and Implementation Branch 3
Pesticide Re-Evaluation Division
Office of Pesticide Programs
If you have any questions about this letter, please contact Darius Stanton by phone at 703-347-
0433, or via email at Stanton.Darius@epa.gov
.
Sincerely,
Linda Arrington, Branch Chief
Risk Management and Implementation Branch 4
Pesticide Re-Evaluation Division
Office of Pesticide Programs
Enclosure
ENCLOSURE: Stamped label
(Master label)
(Master label)
THIAMETHOXAM GROUP 4A INSECTICIDE
MEFENOXAM GROUP 4 FUNGICIDE
SEDAXANE GROUP 7 FUNGICIDE
FLUDIOXONIL GROUP 12 FUNGICIDE
SYT0113
Insecticide with Fungicides
MEFENOXAM GROUP 4 FUNGICIDE
SEDAXANE GROUP 7 FUNGICIDE
FLUDIOXONIL GROUP 12 FUNGICIDE
SYT0113
Insecticide with Fungicides
A seed treatment product for protection against damage from listed insects, seed-borne
diseases, and seedling diseases on soybean
Active Ingredients:
Thiamethoxam1 ............................................................................. 20.00 %
Mefenoxam2 .................................................................................... 5.99 %
Fludioxonil3 ...................................................................................... 1.00 %
Sedaxane4 ....................................................................................... 1.00 %
Other Ingredients: 72.01 %
Total: 100.00 %
1CAS No. 153719-23-4
2CAS No. 70630-17-0 and CAS No. 69516-34-3
3CAS No. 131341-86-1
4CAS No. 874967-67-6
One gallon of SYT0113 contains 1.90 lb thiamethoxam, 0.57 lb mefenoxam, 0.09 lb
fludioxonil and 0.09 lb sedaxane.
KEEP OUT OF REACH OF CHILDREN.
CAUTION
See additional precautionary statements and directions for use in booklet [on label].
EPA Reg. No. 100-1459
EPA Est. XXXXX
SYT0113 1459 MAS 0113
Net Contents
Sep 20, 2019
diseases, and seedling diseases on soybean
Active Ingredients:
Thiamethoxam
1 ............................................................................. 20.00 %
Mefenoxam2 .................................................................................... 5.99 %
Fludioxonil3...................................................................................... 1.00 %
Sedaxane4....................................................................................... 1.00 %
Other Ingredients: 72.01 %
Total: 100.00 %
1CAS No. 153719-23-4
2CAS No. 70630-17-0 and CAS No. 69516-34-3
3CAS No. 131341-86-1
4CAS No. 874967-67-6
One gallon of SYT0113 contains 1.90 lb thiamethoxam, 0.57 lb mefenoxam, 0.09 lb
fludioxonil and 0.09 lb sedaxane.
KEEP OUT OF REACH OF CHILDREN.
CAUTION
See additional precautionary statements and directions for use in booklet [on label].
EPA Reg. No. 100-1459
EPA Est. XXXXX
Net Contents
Jun 22, 2026
100-1459
2
@@ -123,7 +103,7 @@ x Do not give anything by mouth to an unconscious
person.
Have the product container or label with you when calling a poison control center
or doctor or going for treatment.
HOT LINE NUMBER
HOTLINE NUMBER
For 24-Hour Medical Emergency Assistance (Human or Animal)
Or Chemical Emergency Assistance (Spill, Leak, Fire or Accident)
Call
@@ -147,8 +127,8 @@ Applicators and other handlers must wear:
x Long-sleeved shirt and long pants
x Chemical-resistant gloves made of barrier laminate, butyl rubber t 14 mils, nitrile
rubber t 14 mils, neoprene rubber t 14 mils, polyvinyl chloride [PVC] t 14 mils, or
Viton® t 14 mils
rubber t 14 mils, neoprene rubber t 14 mils, polyvinyl chloride (PVC) t 14 mils, or
Viton™ t 14 mils
x Shoes plus socks
@@ -157,12 +137,13 @@ exist for washables, use detergent and hot water. Keep and wash PPE separately f
other laundry.
3
Engineering Control Statements
When handlers use closed systems in a manner that meets the requirements listed in
the Worker Protection Standard (WPS) for agricultural pesticides [40 CFR 170.240(d)(4-
6)], the handler PPE requirements may be reduced or modified as specified in the WPS.
the Worker Protection Standard (WPS) for agricultural pesticides (40 CFR 170.607 (d)
and (e)), the handler PPE requirements may be reduced or modified as specified in the
WPS.
User Safety Recommendations
@@ -173,7 +154,6 @@ toilet.
x Remove clothing/PPE immediately if pesticide gets inside. Then wash
thoroughly and put on clean clothing.
Environmental Hazards
This product is toxic to wildlife, freshwater and estuarine/marine fish and highly toxic to
@@ -187,12 +167,12 @@ possible as a result of exposure to translocated residues in blooming crops.
Groundwater Advisory:
Thiamethoxam has properties and characteristics associated with chemicals detected in
ground water. This chemical may leach into the ground water if used in areas where
groundwater. This chemical may leach into the groundwater if used in areas where
soils are permeable, particularly where the water table is shallow.
Mefenoxam is known to leach through soil into ground water under certain conditions as
Mefenoxam is known to leach through soil into groundwater under certain conditions as
a result of agricultural use. Use of this chemical in areas where soils are permeable,
particularly where the water table is shallow, may result in ground water contamination.
particularly where the water table is shallow, may result in groundwater contamination.
Physical and Chemical Hazards
@@ -244,7 +224,7 @@ SYNGENTA.
5
DIRECTIONS FOR USE
It is a violation of Federal law to use this product in a manner inconsistent with its
It is a violation of federal law to use this product in a manner inconsistent with its
labeling.
For use in commercial seed treatment facilities. Use is also permitted as an end-use
@@ -282,7 +262,7 @@ treated, such as plants, soil, or water is:
x Coveralls
x Chemical-resistant gloves made of barrier laminate, butyl rubber t 14 mils,
nitrile rubber t 14 mils, neoprene rubber t 14 mils, polyvinyl chloride
[PVC] t 14 mils, or Viton® t 14 mils
(PVC) t 14 mils, or Viton t 14 mils
x Shoes plus socks
6
@@ -318,22 +298,25 @@ Fludioxonil fungicide is active against Fusarium, Rhizoctonia, and suppresses se
borne Sclerotinia and Phomopsis species.
Sedaxane fungicide is active against seed decay, seedling blight and damping-off
casued by Rhizoctonia species.
caused by Rhizoctonia species.
Resistance Management
MEFENOXAM GROUP
MEFENOXAM GROUP
4 FUNGICIDE
SEDAXANE GROUP 7 FUNGICIDE
FLUDIOXONIL GROUP 12 FUNGICIDE
Fungicide Resistance Management
For resistance management, please note that SYT0113 contains Group 4/mefenoxam,
Group 7/sedaxane, and Group 12/fludioxonil fungicides. Any fungal population may
contain individuals naturally resistant to SYT0113 and other Group 4, Group 7, or Group
12 fungicides. A gradual or total loss of pest control may occur over time if these
fungicides are used repeatedly in the same fields. Appropriate resistance-management
strategies should be followed.
12 fungicides. A gradual or total loss of pest control may occur over time if these
7
fungicides are used repeatedly in the same fields. Appropriate resistance-management
strategies should be followed.
Mefenoxam belongs to the phenylamide class of chemistry which interferes with fungal
RNA synthesis. Sedaxane is a succinate dehydrogenase inhibitor (SDHI) and belongs
to the carboxamide class of chemistry which disrupt cellular respiration and energy
@@ -345,87 +328,89 @@ To delay fungicide resistance, take one or more of the following steps:
x Rotate the use of SYT0113 or other Group 4, Group 7, or Group 12 fungicides
within a growing season sequence with different groups that control the same
pathogens.
x Use tank mixtures with fungicides from a different group that are equally effective
on the target pest when such use is permitted. Use at least the minimum
application rate as labeled by the manufacturer.
x Adopt an integrated disease management program for fungicide use that
includes scouting, uses historical information related to pesticide use, and crop
rotation, and which considers host plant resistance, impact of environmental
conditions on disease development, disease thresholds, as well as cultural,
biological and other chemical control practices.
x Where possible, make use of predictive disease models to effectively time
fungicide application. Note that using predictive models alone is not sufficient to
manage resistance.
x Monitor treated fungal populations for resistance development.
x Contact your local extension specialist or certified crop advisor for any additional
pesticide resistance-management and/or IPM recommendations for specific
crops and pathogens.
x For further information or to report suspected resistance contact Syngenta at 1-
866-SYNGENT(A) (866-796-4368). You can also contact your pesticide
distributor or university extension specialist to report resistance.
distributor or university extension specialist to report resistance.
Syngenta encourages responsible product stewardship to ensure effective long-term
control of the fungal diseases on this label.
THIAMETHOXAM GROUP 4A INSECTICIDE
THIAMETHOXAM GROUP
4A INSECTICIDE
Insecticide Resistance Management
SYT0113 contains a Group 4A insecticide (thiamethoxam, belonging to the
neonicotinoid class of chemistry). Insect biotypes with acquired or inherent resistance
to Group 4A insecticides may eventually dominate the insect population if Group 4A
to Group 4A insecticides may eventually dominate the insect population if Group 4A
insecticides are used repeatedly as the predominant method of control for targeted
8
insecticides are used repeatedly as the predominant method of control for targeted
species. This may result in partial or total loss of control of those species by SYT0113
or other Group 4A insecticides.
Thiamethoxam is a systemic insecticide belonging to the neonicotinoid class of
chemistry which includes nicotinic acetylcholine receptor (nAChR) agonists.
In order to maintain susceptibility to this class of chemistry:
x Avoid using Group 4A insecticides exclusively for season long control of insect
species with more than one generation per crop season.
x For insect species with successive or overlapping generations, apply SYT0113 or
other Group 4A insecticides using a “treatment window” approach. A treatment
window is a period of time as defined by the stage of crop development and/or the
biology of the pests of concern. Within the treatment window, depending on the
length of residual activity, there may either be single or consecutive applications
(seed treatment, soil, foliar, unless otherwise stated in the Directions for Use) of the
Group 4A insecticides. Do not exceed the maximum SYT0113 allowed per growing
season.
x Following a treatment window of Group 4A insecticides, rotate to a treatment window
of effective products with a different mode of action before making additional
applications of Group 4A insecticides.
x A treatment window rotation, along with other IPM practices for the crop and use
area, is considered an effective strategy for preventing or delaying a pest’s ability to
develop resistance to this class of chemistry.
x If resistance is suspected, do not reapply SYT0113 or any other Group 4A
insecticides.
Other Insect Resistance Management (IRM) practices include:
ƒ Incorporating IPM techniques into your insect control program.
ƒ Monitoring treated insect populations for loss of field efficacy.
ƒ Using tank-mixtures or premixes with insecticides from a different target site of
action group as long as the involved products are all registered for the same crop
outlet and effective rates are applied.
For additional information on Insect Resistance Management:
ƒ Contact your local extension specialist, certified crop advisor and/or product
manufacturer for additional insect resistance management recommendations.
ƒ Visit the Insecticide Resistance Action Committee (IRAC) on the web at:
http://www.irac-online.org/.
To delay insecticide resistance, take the following steps:
x Rotate the use of SYT0113 or other Group 4A insecticides within a growing
season, or among growing seasons, with different groups that control the same
pests.
x Use tank mixtures with insecticides from a different group that are equally
effective on the target pest when such use is permitted. Do not rely on the same
mixture repeatedly for the same pest population. Consider any known cross-
resistance issues (for the targeted pests) between the individual components of a
mixture. In addition, consider the following recommendations provided by the
Insecticide Resistance Action Committee (IRAC):
o Individual insecticides selected for use in mixtures should be highly
effective and be applied at the rates at which they are individually
registered for use against the target species.
o Mixtures with components having the same IRAC mode of action
classification are not recommended for insect resistance management.
o When using mixtures, consider any known cross-resistance issues
between the individual components for the targeted pest(s).
o Mixtures become less effective if resistance is already developing to one
or both active ingredients, but they may still provide pest management
benefits.
o The insect resistance management benefits of an insecticide mixture are
greatest if the two components have similar periods of residual insecticidal
activity. Mixtures of insecticides with unequal periods of residual
insecticide activity may offer an insect resistance management benefit
only for the period where both insecticides are active.
x Adopt an integrated pest management program for insecticide/acaricides use
that includes scouting, uses historical information related to pesticide use, crop
rotation, record keeping, and which considers cultural, biological and other
chemical control practices.
x Monitor after application for unexpected target pest survival. If the level of
survival suggests the presence of resistance, consult with your local university
specialist or certified pest control advisor.
x Contact your local extension specialist or certified crop advisors for any
additional pesticide resistance-management and/or IPM recommendations for
the specific site and pest problems in your area.
x For further information or to report suspected resistance contact Syngenta at 1-
866-796-4368.
9
Syngenta encourages responsible product stewardship to ensure effective long term
control of the insects on this label.
MIXING PROCEDURES
9
MIXING PROCEDURES
Important: Always re-circulate SYT0113 thoroughly before using.
The typical density of SYT0113 is 9.48 pounds per gallon. Consult the manufacturer of
@@ -457,78 +442,137 @@ Allow seed to dry before bagging.
Follow planter manufacturer specifications for use of talc or other hopper box additives
at planting. Seed must be completely dry before adding to planter.
Use an EPA approved dye/colorant that imparts an unnatural color to the seed as
required in 40CFR 153.155(c).
Required Dye Statement: Seed treated with this product must be visually identifiable
from untreated seed by the use of an approved colorant or dye to prevent accidental
use of treated seed as food for humans or feed for animals. Refer to 21 CFR, Part 2.25.
Any colorant or dye added to treated seed must be cleared for use in accordance with
40 CFR, Part 153.155(c).
10
SEED BAG LABEL REQUIREMENTS
The Federal Seed Act requires that bags containing treated seeds shall be labeled with
Use of On-Farm Treated Seed (when treated seed are not for sale or distribution)
Treated seed sold or distributed for a use not permitted by the following labeling does
not qualify as an exempted treated article under 40 CFR 152.25(a) and is therefore sale
or distribution of an unregistered pesticide, pursuant to FIFRA section 12.
x Store treated seed away from food and feedstuffs.
x DO NOT allow children, pets, or livestock to have access to treated seed.
x Treated seed are for planting purposes only. DO NOT use for food, feed, or oil
purposes. DO NOT use treated seed for fuel or ethanol production purposes.
x Wear long-sleeved shirt, long pants, sh oes, socks, and chemical-resistant gloves
when handling treated seed.
x DO NOT plant treated seed by broadcasting to the soil surface. Ensure that all
planted seeds are thoroughly incorporated by the planter during planting. Additional
incorporation may be required to thoroughly cover exposed seeds.
x Treated seed exposed on the soil surface may be hazardous to wildlife. Cover or
collect treated seed spilled during loading and planting (such as in row ends).
x Treated seed must be planted into the soil at a depth greater than 1 inch.
x Manage excess treated seed (e.g., spilled, unused, or expired treated seed) by one
or more of the following methods:
o Collect excess treated seed for reuse for planting.
o Bury excess treated seed (only allowed if totaling 1 pound or less) at least 30 feet
away from bodies of water at a depth of 6 inches or double the planting depth,
whichever is greater.
o Dispose of excess treated seed by placing them in a landfill in accordance with
applicable laws in your state.
o Return excess treated seed to the supplier if permitted by the state.
x DO NOT contaminate bodies of water when disposing of equipment wash water.
x Advisory Dust-Reducing Technique: The use of seed flow lubricants or polymer
coatings may help decrease the amount of dust released during planting. Follow the
recommendations of the planter manufacturer regarding the use of seed flow
lubricants.
11
Seed Treatment in Commercial Facilities or Seed Treatment on Farm (when
treated seed are to be sold or distributed) – Seed Bag Labeling Requirements
The Federal Seed Act requires that bags containing treated seed shall be labeled with
the following statements:
x This seed has been treated with thiamethoxam insecticide and fludioxonil,
mefenoxam, and sedaxane fungicides.
x Do not use for feed, food, or oil purposes.
x User is responsible for ensuring that the seed bag meets all requirements under
the Federal Seed Act.
x DO NOT use for food, feed, or oil purposes.
In addition, the U.S. Environmental Protection Agency requires the following statements
on bags containing seeds treated with SYT0113:
10
The U.S. Environmental Protection Agency requires that bags containing treated seed
shall be labeled with the following statements. Any seed treated with SYT0113 that is
sold or distributed without these statements or that is sold or distributed for a use not
permitted by the following labeling does not qualify as an exempted treated article under
40 CFR 152.25(a) and is therefore sale or distribution of an unregistered pesticide,
pursuant to FIFRA section 12(a)(1)(A).
x Ground Water Advisory:
Thiamethoxam has properties and characteristics associated with chemicals
detected in ground water. This chemical may leach into the ground water if
used in areas where soils are permeable, particularly where the water table is
shallow.
Mefenoxam is known to leach through soil into ground water under certain
conditions as a result of agricultural use. Use of this chemical in areas where
soils are permeable, particularly where the water table is shallow, may result in
ground water contamination.
x Pollinator Precautions:
Thiamethoxam is highly toxic to bees, and effects are possible as a result of
exposure to translocated residues in blooming crops.
x Excess treated seed may be used for ethanol production only if (1) by-products
are not used for livestock feed and (2) no measurable residues of pesticide
remain in the ethanol by- products that are used in agronomic practice.
x Do not allow children, pets, or livestock to have access to treated seed.
x Store away from feeds and foodstuffs.
x Wear long-sleeved shirt, long pants and chemical resistant gloves when handling
This seed has been treated with SYT0113 (EPA Reg No. 100-1459) containing
fludioxonil, mefenoxam, sedaxane, and thiamethoxam. Any seed treated with SYT0113
that is sold or distributed for a use not permitted by the following labeling does not
qualify as an exempted treated article under 40 CFR 152.25(a) and is therefore sale or
distribution of an unregistered pesticide, pursuant to FIFRA section 12(a)(1)(A).
x The contents of this bag are for planting purposes only. DO NOT use for food,
feed, or oil purposes. DO NOT use for fuel or ethanol production purposes.
x Store treated seed away from food and feedstuffs.
x DO NOT allow children, pets, or livestock to have access to treated seed.
x Wear long-sleeved shirt, long pants and chemical-resistant gloves when handling
treated seed.
x Treated seeds exposed on soil surface may be hazardous to wildlife. Cover or
collect treated seeds spilled during loading.
x DO NOT plant treated seed by broadcasting to the soil surface. Ensure that all
planted seeds are thoroughly incorporated by the planter during planting.
Additional incorporation may be required to thoroughly cover exposed seeds.
x Treated seed exposed on soil surface may be hazardous to wildlife. Cover or
collect treated seed spilled during loading and planting (such as in row ends).
x Treated seed must be planted into the soil at a depth greater than 1 inch.
x Dispose of all excess treated seed. Leftover treated seed may be doublesown
around the headland or buried away from water sources in accordance with local
requirements.
x Do not contaminate water bodies when disposing of planting equipment wash
waters.
x Manage excess treated seed (e.g., spilled, unused, or expired treated seed) by
one or more of the following methods:
o Collect excess treated seed for reuse for planting.
o Bury excess treated seed (only allowed if totaling 1 pound or less) at least 30
feet away from bodies of water at a depth of 6 inches or double the planting
depth, whichever is greater.
o Dispose of excess treated seed by placing them in a landfill in accordance
with applicable laws in your state.
o Return excess treated seed to the supplier if permitted by the state.
x DO NOT contaminate water bodies when disposing of planting equipment wash
waters.
12
x Dispose of seed packaging in accordance with local requirements.
x For seed treated with SYT 0511, do not graze or feed livestock on treated areas
for 45 days after planting.
x For seed treated with SYT0113, DO NOT graze or feed livestock on treated
areas for 45 days after planting.
x In the event of a crop failure or harvest of a crop grown from SYT0113 treated
seed, the field may be replanted immediately to canola, soybean, barley, oat, rye
triticale and wheat.
x Alfalfa, Brassica (cole) leafy vegetables, buckwheat, corn, pearl millet, proso
millet, popcorn, rice (dry-seeded), sorghum, teosinte, wild rice, cotton, cucurbit
vegetables, dry bulb onions, fruiting vegetables, leafy vegetables, legume
x Alfalfa, Brassica (Cole) leafy vegetables, buckwheat, corn, pearl millet, Proso
millet, popcorn, rice (dry-seeded), sorghum, teosinte, wild rice, cotton, Cucurbit
vegetables, dry bulb onions, fruiting vegetables, leafy vegetables, Legume
vegetables, mint (peppermint and spearmint), oil seed crops (black mustard
seed, borage seed, crambe seed, field mustard seed, flax seed, Indian mustard
seed, Indian rapeseed seed, peanuts, rapeseed seed, and safflower seed), root
vegetables, strawberry, sunflowers, tobacco, and tuberous and corm vegetables
may be planted 30 days from the date the SYT0113 treated seed was planted.
x For any other crop, the minimum plant back interval is 120 days from the date the
SYT0113 treated seed was planted. A cover crop other than the crops listed
above that is planted for erosion control or soil improvement may be planted
11
sooner than the 120 day interval; however, the crop may not be grazed or
may be planted 30 days from the date the SYT0113 treated seed were planted.
x For any other crop, the minimum plant-back interval is 120 days from the date
the SYT0113 treated seed were planted. A cover crop other than the crops listed
above that is planted for erosion control or soil improvement may be planted
sooner than the 120-day interval; however, the crop may not be grazed or
harvested for food or feed.
x Do not use at a rate that will result in more than 0.226 lb thiamethoxam per acre
(120.6 grams ai/A) per year as a seed treatment application.
x DO NOT apply more than 0.266 lb thiamethoxam per acre (120.6 g ai/A), 0.052
lb mefenoxam or metalaxyl per acre (23 g ai/A), or 0.046 lb sedaxane per acre
(19 g ai/A) per calendar year as a seed-treatment application.
x This seed has been treated with 0.0756 mg ai thiamethoxam per seed.
x Do not apply a neonicotinoid insecticide within 45 days of planting seed treated
x DO NOT apply a neonicotinoid insecticide within 45 days of planting seed treated
with SYT0113.
x Groundwater Advisory: Thiamethoxam has properties and characteristics
associated with chemicals detected in groundwater. This chemical may leach
into the groundwater if used in areas where soils are permeable, particularly
where the water table is shallow. Mefenoxam is known to leach through soil into
groundwater under certain conditions as a result of agricultural use. Use of this
chemical in areas where soils are permeable, particularly where the water table
is shallow, may result in groundwater contamination.
x Pollinator Precautions: Thiamethoxam is highly toxic to bees, and effects are
possible as a result of exposure to translocated residues in blooming crops.
x Advisory Dust-Reducing Technique: The use of seed flow lubricants or
polymer coatings may help decrease the amount of dust released during
planting. Follow the recommendations of the planter manufacturer regarding the
use of seed flow lubricants.
x [All seed bag tags must be legible and set in at least 8-point font size.]
13
CROP USE DIRECTIONS
When applied according to the SYT0113 RATE TABLE, SYT0113 provides early
@@ -550,8 +594,7 @@ Crop
Rate of SYT0113
Soybean, including
soybean, vegetable
soybean, vegetable
fl oz per
100 lb seed
@@ -593,16 +636,19 @@ Total = 0.1058 mg
1The mg ai per seed and fl oz SYT0113 per 100 lb seed and 140,000 seeds rates are based on 3,000
seeds per pound.
DO NOT apply more than 0.052 lb ai/Acre (23 g ai/Acre) per calendar year of
mefenoxam- or metalaxyl-containing products as a seed treatment on Soybean
(including soybean, vegetable).
Stored Grain Protection
When treated according to the directions for post-planting protection against listed
pests, SYT0113 will also provide protection during post treatment storage of the
12
pests, SYT0113 will also provide protection during post treatment storage of the
soybean seed against damage from the following stored grain insects: Indian Meal
Moth (Plodia interpunctella), Rice Weevil (Sitophilus oryza), Red Flour Beetle (Tribolium
castaneum), and Lesser Grain Borer (Rhizopertha dominica).
castaneum), and Lesser Grain Borer (Rhizopertha dominica).
14
If the soybean seed to be treated has existing infestations of stored grain insects,
fumigate the seed with a registered product approved for such use, prior to treating with
SYT0113 and bagging.
@@ -644,13 +690,13 @@ Non-refillable container. Do not reuse or refill this container. Triple rinse co
equivalent) promptly after emptying. Triple rinse as follows: empty the remaining
contents into application equipment or a mix tank and drain for 10 seconds after the flow
begins to drip. Fill the container ¼ full with water. Replace and tighten closures. Tip
container on its side and roll it back and forth, ensuring at least one complete revolution,
13
container on its side and roll it back and forth, ensuring at least one complete revolution,
for 30 seconds. Stand the container on its end and tip it back and forth several times.
Turn the container over onto its other side and tip it back and forth several times.
Empty the rinsate into application equipment or a mix tank or store rinsate for later use
and disposal. Repeat this procedure two more times. Then offer for recycling if
and disposal. Repeat this procedure two more times. Then offer for recycling if
15
available or puncture and dispose of in a sanitary landfill, or by incineration, or by other
procedures approved by state and local authorities.
@@ -670,13 +716,13 @@ CONTAINER IS NOT SAFE FOR FOOD, FEED, OR DRINKING WATER!
The ALLIANCE FRAME, the SYNGENTA Logo, and the PURPOSE ICON are
Trademarks of a Syngenta Group Company
Viton® is a registered trademark of E.I. DuPont de Nemours and Company
©20XX Syngenta
Viton™ is a trademark of The Chemours Company FC, LLC
© 20XX Syngenta
For non-emergency (e.g., current product information), call
Syngenta Crop Protection at 1-800-334-9481.
Syngenta Crop Protection at 1-866-796-4368.
Manufactured for:
Syngenta Crop Protection, LLC
@@ -684,5 +730,5 @@ P. O. Box 18300
Greensboro, North Carolina 27419-8300
SYT0113 1459 MAS 0113 AMEND 0618 - sb – 6/28/2018
000100-01459.20180628.SYT0113.AMEND.JUN2018
SYT0113 1459 MAS 0919 AMEND-B 0226-CL – jeb – 05/21/2026
000100-01459.20260216B.SYT0113.AMEND.FEB2026-CL.PDF