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- Registrant: SYNGENTA CROP PROTECTION, LLC
- Signal word: Caution
- Active ingredients: Thiabendazole (2.24%); Thiamethoxam (22.4%); Fludioxonil (1.12%); Metalaxyl-M (3.35%); Sedaxane (1.12%)
- Label accepted: 2019-09-20
- Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000100-01559-20190920.pdf
- Label accepted: 2026-06-22
- Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000100-01559-20260622.pdf
---
UNITED STATES ENVIRONMENTAL PROTECTION AGENCY
WASHINGTON, DC 20460
Reg Review Label Acceptable v.20151230
OFFICE OF CHEMICAL SAFETY
AND POLLUTION PREVENTION
September 20, 2019
Ricky Kyaw
Regulatory Product Manager
Syngenta Crop Protection, LLC
PO Box 18300
Greensboro, NC 27419
Subject: Registration Review Label Mitigation for Fludioxonil and Mefenoxam
Product Name: THX/MXM/FLD/TBZ/SDX FS
EPA Registration Number: 100-1559
Application Date: 2/1/2019
Decision Number: 554975; 554976
Dear Mr. Kyaw:
The Agency, in accordance with the Federal Insecticide, Fungicide and Rodenticide Act
(FIFRA), as amended, has completed reviewing all of the information submitted with your
application to support the Registration Review of the above referenced product in connection
with the Fludioxonil and Mefenoxam Interim Decisions, and has concluded that your submission
is acceptable. The label referred to above, submitted in connection with registration under
FIFRA, as amended, is acceptable.
Should you wish to add/retain a reference to the company’s website on your label, then please be
aware that the website becomes labeling under the Federal Insecticide Fungicide and Rodenticide
Act and is subject to review by the Agency. If the website is false or misleading, the product
would be misbranded and unlawful to sell or distribute under FIFRA section 12(a)(1)(E). 40
CFR 156.10(a)(5) list examples of statements EPA may consider false or misleading. In addition,
regardless of whether a website is referenced on your product’s label, claims made on the
website may not substantially differ from those claims approved through the registration process.
Therefore, should the Agency find or if it is brought to our attention that a website contains false
or misleading statements or claims substantially differing from the EPA approved registration,
the website will be referred to the EPA’s Office of Enforcement and Compliance.
A copy of your label stamped “Accepted” is enclosed. Products shipped after 12 months from the
date of this amendment must bear the new revised label. Your release for shipment of the
product bearing the amended label constitutes acceptance of these conditions. If these conditions
are not complied with, the registration will be subject to cancellation in accordance with FIFRA
section 6.
June 22, 2026
Patsy Laird, Ricky Kyaw
Regulatory Managers
Syngenta Crop Protection, LLC
P. O. Box 18300
Greensboro, NC 27419
Patsy.laird@syngeta.com, ricky.kyaw@syngetna.com
Subject: Label Amendment - Registration Review Mitigation for Sedaxane and
Thiabendazole
Product Name: THX/MXM/FLD/TBZ/SDX FS
EPA Registration Number: 100-1559
Case Numbers: 684639 and 482813
Application Dates: February 13, 2026 and December 14, 2020
Dear Patsy Laird and Ricky Kyaw:
The Agency, in accordance with the Federal Insecticide, Fungicide, and Rodenticide Act
(FIFRA), as amended, has completed reviewing all the information submitted with your
application to support the Registration Review of the above referenced product in
connection with the sedaxane and thiabendazole Interim Decisions, and has concluded
that your submission is acceptable. The label referred to above, submitted in connection
with registration under FIFRA, as amended, is acceptable.
Should you wish to add/retain a reference to the company’s website on your label, then
please be aware that the website becomes labeling under the Federal Insecticide,
Fungicide, and Rodenticide Act and is subject to review by the Agency. If the website is
false or misleading, the product would be misbranded and unlawful to sell or distribute
under FIFRA section 12(a)(1)(E). 40 CFR 156.10(a)(5) list examples of statements EPA may
consider false or misleading. In addition, regardless of whether a website is referenced on
your product’s label, claims made on the website may not substantially differ from those
claims approved through the registration process. Therefore, should the Agency find or if it
is brought to our attention that a website contains false or misleading statements or
claims substantially differing from the EPA approved registration, the website will be
referred to the EPA’s Office of Enforcement and Compliance Assurance.
Page 2 of 2
EPA Reg. No. 100-1559
Decision No. 554975; 554976
Case No. 684639 and 482813
If you have any questions about this letter, please contact Darius Stanton by phone at 703-347-
0433, or via email at Stanton.Darius@epa.gov
.
A stamped copy of your labeling is enclosed for your records. This labeling
supersedes all previously accepted labeling and must be used at your next label
printing. You must submit one copy of the final printed labeling before you release
the product for shipment with the new labeling. In accordance with 40 CFR
152.130(c), you may distribute or sell this product under the previously approved
labeling for 12 months from the date of this letter. After 12 months, you may only
distribute or sell this product if it bears this new revised labeling or subsequently
approved labeling. “To distribute or sell” is defined under FIFRA section 2(gg) and
its implementing regulation at 40 CFR 152.3.
Sincerely,
If you have any questions about this letter, please contact Samantha Carter by phone at
(202) 566-1179, or via email at carter.samantha@epa.gov.
S i n c e r e l y ,
J a c l y n P y n e , T e a m L e a d e r
R i s k M a n a g e m e n t a n d I m p l e m e n t a t i o n B r a n c h 3
P e s t i c i d e R e - E v a l u a t i o n D i v i s i o n
O f f i c e o f P e s t i c i d e P r o g r a m s
Linda Arrington, Branch Chief
Risk Management and Implementation Branch 4
Pesticide Re-Evaluation Division
Office of Pesticide Programs
Enclosure
ENCLOSURE: Stamped label
THX/MXM/FLD/TBZ/SDX FS
Page 1
(MASTER)
THX/MXM/FLD/TBZ/SDX FS
Page 1
(MASTER)
THIAMETHOXAM GROUP 4A INSECTICIDE
THIABENDAZOLE GROUP 1 FUNGICIDE
MEFENOXAM GROUP 4 FUNGICIDE
SEDAXANE GROUP 7 FUNGICIDE
FLUDIOXONIL GROUP 12 FUNGICIDE
THX/MXM/FLD/TBZ/SDX FS
Insecticide with Fungicides
THIABENDAZOLE GROUP 1 FUNGICIDE
MEFENOXAM GROUP 4 FUNGICIDE
SEDAXANE GROUP 7 FUNGICIDE
FLUDIOXONIL GROUP 12 FUNGICIDE
THX/MXM/FLD/TBZ/SDX FS
Insecticide with Fungicides
A seed treatment product for protection against damage from listed: insects, seed-borne
diseases, and seedling diseases on soybean
Active Ingredients:
Thiamethoxam1 ................................................................................................. 22.40%
Mefenoxam2 ........................................................................................................ 3.35%
Thiabendazole3 ................................................................................................... 2.24%
Fludioxonil4 .......................................................................................................... 1.12%
Sedaxane5 ........................................................................................................... 1.12%
Other Ingredients: 69.77%
Total: 100.00%
1CAS No. 153719-23-4
2CAS No. 70630-17-0 and CAS No. 69516-34-3
3CAS No. 148-79-8
4CAS No. 131341-86-1
5CAS No. 874967-67-6
One gallon of THX/MXM/FLD/TBZ/SDX FS contains 2.16 lb thiamethoxam, 0.32 lb
mefenoxam, 0.22 Lb thiabendazole, 0.11 lb fludioxonil and 0.11 lb sedaxane.
KEEP OUT OF REACH OF CHILDREN.
CAUTION
See additional precautionary statements and directions for use in booklet [on label].
EPA Reg. No. 100-1559
diseases, and seedling diseases on soybean
Active Ingredients:
Thiamethoxam
1 ................................................................................................. 22.40%
Mefenoxam2 ........................................................................................................ 3.35%
Thiabendazole3 ................................................................................................... 2.24%
Fludioxonil4.......................................................................................................... 1.12%
Sedaxane5........................................................................................................... 1.12%
Other Ingredients: 69.77%
Total: 100.00%
1CAS No. 153719-23-4
2CAS No. 70630-17-0 and CAS No. 69516-34-3
3CAS No. 148-79-8
4CAS No. 131341-86-1
5CAS No. 874967-67-6
One gallon of THX/MXM/FLD/TBZ/SDX FS contains 2.16 lb thiamethoxam, 0.32 lb
mefenoxam, 0.22 Lb thiabendazole, 0.11 lb fludioxonil and 0.11 lb sedaxane.
KEEP OUT OF REACH OF CHILDREN.
CAUTION
See additional precautionary statements and directions for use in booklet [on label].
EPA Reg. No. 100-1559
EPA Est.
_______________
Net Contents
Sep 20, 2019
_______________
Net Contents
06/22/2026
100-1559
THX/MXM/FLD/TBZ/SDX FS
Page 2
(MASTER)
FIRST AID
If swallowed x Call a poison control center or doctor immediately for treatment
advice.
@@ -131,7 +118,7 @@ or doctor.
x Do not give anything to an unconscious person.
Have the product container or label with you when calling a poison control center or
doctor or going for treatment.
HOT LINE NUMBER
HOTLINE NUMBER
For 24-Hour Medical Emergency Assistance (Human or Animal)
or Chemical Emergency Assistance (Spill, Leak, Fire, or Accident),
Call
@@ -151,9 +138,9 @@ PERSONAL PROTECTIVE EQUIPMENT (PPE)
Applicators and other handlers must wear:
x Long-sleeved shirt and long pants.
x Chemical-resistant gloves made of barrier laminate, butyl rubber •14 mils, nitrile
rubber •14 mils, neoprene rubber •14 mils, polyvinyl chloride (PVC) •14 mils, or
Viton® •14 mils
x Chemical-resistant gloves made of EDUULHUODPLQDWHEXW\OUXEEHU•PLOVQLWULOH
UXEEHU•PLOVQHRSUHQHUXEEHU•PLOVSRO\YLQ\OFKORULGH 39& •PLOVRU
9LWRQ™ •PLOV
x Shoes plus socks.
Follow manufacturer’s instructions for cleaning/maintaining PPE. If no such instructions
@@ -163,15 +150,15 @@ other laundry.
Engineering Controls
When handlers use closed systems in a manner that meets the requirements listed in
the Worker Protection Standard (WPS) for agricultural pesticides [40 CFR 170.240(d)(4-
6)], the handler PPE requirements may be reduced or modified as specified in the WPS.
the Worker Protection Standard (WPS) for agricultural pesticides (40 CFR 170.607 (d)
and (e)), the handler PPE requirements may be reduced or modified as specified in the
WPS.
THX/MXM/FLD/TBZ/SDX FS
Page 3
(MASTER)
USER SAFETY RECOMMENDATIONS
Users should:
@@ -184,27 +171,30 @@ x Remove PPE immediately after handling this product. Wash the outside of
gloves before removing. As soon as possible, wash thoroughly and change
into clean clothing.
ENVIRONMENTAL HAZARDS
This product is toxic to wildlife, freshwater and estuarine/marine fish and highly toxic to
aquatic invertebrates. Runoff may be hazardous to aquatic organisms in neighboring
areas. Exposed treated seed may be hazardous to wildlife. Cover seed spilled during
loading. Do not contaminate water when disposing of equipment washwater or rinsate.
areas. Do not contaminate water when disposing of equipment washwater or rinsate.
Pollinator Precautions
Thiamethoxam is highly toxic to bees exposed to direct treatment, and effects may be
possible as a result of exposure to translocated residues in blooming crops.
Non-Target Organism Advisory Statement
This product may adversely impact non-target organisms feeding on treated seed.
Protect the non-target organisms by following label directions intended to minimize
availability of treated seed to non-target organisms.
Groundwater Advisory
Thiamethoxam has properties and characteristics associated with chemicals detected in
ground water. This chemical may leach into the ground water if used in areas where
groundwater. This chemical may leach into the groundwater if used in areas where
soils are permeable, particularly where the water table is shallow.
Mefenoxam is known to leach through soil into ground water under certain conditions as
a result of label use. This chemical may leach into the ground water if used in areas
Mefenoxam is known to leach through soil into groundwater under certain conditions as
a result of label use. This chemical may leach into the groundwater if used in areas
where soils are permeable, particularly where the water table is shallow.
Physical and Chemical Hazards
@@ -247,7 +237,7 @@ To the extent permitted by applicable law, in no event shall Syngenta be liable
incidental, consequential or special damages resulting from the use or handling of this
product. TO THE EXTENT PERMITTED BY APPLICABLE LAW, THE EXCLUSIVE
REMEDY OF THE USER OR BUYER, AND THE EXCLUSIVE LIABILITY OF
SYNGENTA AND SELLER FOR ANY AND ALL CLAIMS, LOSSES, INJURIES OR
SYNGENTA AND SELLER FOR ANY AND A LL CLAIMS, LOSSES, INJURIES OR
DAMAGES (INCLUDING CLAIMS BASED ON BREACH OF WARRANTY,
CONTRACT, NEGLIGENCE, TORT, STRICT LIABILITY OR OTHERWISE)
RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, SHALL BE THE
@@ -265,7 +255,7 @@ Page 5
DIRECTIONS FOR USE
It is a violation of Federal law to use this product in a manner inconsistent with its
It is a violation of federal law to use this product in a manner inconsistent with its
labeling.
For use in commercial seed treatment facilities. Use is also permitted as an end-use
@@ -318,9 +308,9 @@ Protection Standard and that involves contact with anything that has been treate
as plants, soil, or water is:
x Coveralls
x Chemical-resistant gloves made of barrier laminate, butyl rubber •14 mils, nitrile
rubber •14 mils, neoprene rubber •14 mils, polyvinyl chloride (PVC) •14 mils, or
Viton® •14 mils
x Chemical-resistant gloves made of EDUULHUODPLQDWHEXW\OUXEEHU•PLOVQLWULOH
UXEEHU•PLOVQHRSUHQHUXEEHU•PLOVSRO\YLQ\OFKORULGH 39& •PLOVRU
9LWRQ•PLOV
x Shoes plus socks
@@ -356,14 +346,16 @@ MEFENOXAM GROUP 4 FUNGICIDE
SEDAXANE GROUP 7 FUNGICIDE
FLUDIOXONIL GROUP 12 FUNGICIDE
For resistance management, please note that THX-MXM/FDL/TBZ/SDX FS contains
Group 1/ thiabendazole, Group 4/ mefenoxam, Group 7/sedaxane and Group
12/fludioxonil fungicides. Any fungal population may contain individuals naturally
Fungicide Resistance Management
For resistance management, please note that THX-MXM/FDL/TBZ/SDX FS contains
THX/MXM/FLD/TBZ/SDX FS
Page 7
(MASTER)
Group 1/ thiabendazole, Group 4/ mefenoxam, Group 7/sedaxane and Group
12/fludioxonil fungicides. Any fungal population may contain individuals naturally
resistant to THX-MXM/FDL/TBZ/SDX FS and other Group 1, Group 4, Group 7 or
Group 12 fungicides. A gradual or total loss of pest control may occur over time if these
fungicides are used repeatedly in the same fields. Appropriate resistance-management
@@ -400,62 +392,74 @@ x For further information or to report suspected resistance contact Syngenta at
Syngent(a) (866-796-4368). You can also contact your pesticide distributor or
university extension specialist to report resistance.
THIAMETHOXAM GROUP
4A INSECTICIDE
THIAMETHOXAM GROUP
4A INSECTICIDE
Insecticide Resistance Management
For resistance management, THX/MXM/FLD/TBZ/SDX FS contains a Group
4A/thiamethoxam insecticide. Any insect population may contain individuals naturally
resistant to THX/MXM/FLD/TBZ/SDX FS and other Group 4A insecticides. The
resistant individuals may dominate the insect population if this group of insecticides are
used repeatedly in the same fields. Appropriate resistance-management strategies
should be followed.
Thiamethoxam is a systemic insecticide belonging to the neonicotinoid class of chemistry
which includes nicotinic acetylcholine receptor (nAChR) agonists.
resistant individuals may dominate the insect population if this group of insecticides are
THX/MXM/FLD/TBZ/SDX FS
Page 8
(MASTER)
used repeatedly in the same fields. Appropriate resistance-management strategies
should be followed.
In order to maintain susceptibility to this class of chemistry:
x Use products at their full, specified doses.
x Use appropriate, well-maintained equipment. Use specified water volumes and apply
at optimal temperatures in order to obtain optimal treatment.
x When rate ranges are given, use the higher rate within the listed rate range when
insect pressure is expected to be high.
x Avoid using a single active ingredient or mode of action (same insecticide group)
exclusively for season long control of insect species with more than one generation
per crop season.
x For insect species with successive or overlapping generations, use a treatment
window approach. A treatment window is a period of time defined by the stage of
crop development and the biology of the pests of concern. Within the treatment
window, depending on the length of residual activity, single or consecutive
applications may be made using seed, in-furrow, or foliar treatments unless
otherwise excluded by product labels. Do not exceed the maximum amount of this
insecticide’s mode of action allowed per growing season.
x Following a treatment window of this insecticide’s mode of action, rotate to a
treatment window of effective products with a different mode of action before making
additional applications of this insecticide.
Thiamethoxam is a systemic insecticide belonging to the neonicotinoid class of chemistry
which includes nicotinic acetylcholine receptor (nAChR) agonists.
Other Insect Resistance Management (IRM) practices include:
ƒ Incorporating IPM techniques into your insect control program.
ƒ Monitoring treated insect populations for loss of field efficacy.
ƒ Using tank-mixtures or premixes with insecticides from a different target site of
action group as long as the involved products are all registered for the same crop
outlet and effective rates are applied.
For additional information on Insecticide or Fungicide Resistance Management:
x Contact Syngenta representatives at 1-800-334-9481
x Contact your local Cooperative Extension Service specialist, pest control advisor, or
certified crop advisor
x Visit the Visit the Insecticide Resistance Action Committee (IRAC) on the web at:
http://www.irac-online.org or the Fungicide Resistance Action Committee (FRAC) on
the web at: http://www.frac.info
Syngenta encourages responsible product stewardship to ensure effective long term
To delay insecticide resistance, take the following steps:
x Rotate the use of THX/MXM/FLD/TBZ/SDX FS or other Group 4A insecticides
within a growing season, or among growing seasons, with different groups that
control the same pests.
x Use tank mixtures with insecticides from a different group that are equally
effective on the target pest when such use is permitted. Do not rely on the same
mixture repeatedly for the same pest population. Consider any known cross-
resistance issues (for the targeted pests) between the individual components of a
mixture. In addition, consider the following recommendations provided by the
Insecticide Resistance Action Committee (IRAC):
o Individual insecticides selected for use in mixtures should be highly
effective and be applied at the rates at which they are individually
registered for use against the target species.
o Mixtures with components having the same IRAC mode of action
classification are not recommended for insect resistance management.
o When using mixtures, consider any known cross-resistance issues
between the individual components for the targeted pest(s).
o Mixtures become less effective if resistance is already developing to one
or both active ingredients, but they may still provide pest management
benefits.
o The insect resistance management benefits of an insecticide mixture are
greatest if the two components have similar periods of residual insecticidal
activity. Mixtures of insecticides with unequal periods of residual
insecticide activity may offer an insect resistance management benefit
only for the period where both insecticides are active.
x Adopt an integrated pest management program for insecticide/acaricides use
that includes scouting, uses historical information related to pesticide use, crop
rotation, record keeping, and which considers cultural, biological and other
chemical control practices.
x Monitor after application for unexpected target pest survival. If the level of
survival suggests the presence of resistance, consult with your local university
specialist or certified pest control advisor.
x Contact your local extension specialist or certified crop advisors for any
additional pesticide resistance-management and/or IPM recommendations for
the specific site and pest problems in your area.
x For further information or to report suspected resistance contact Syngenta at 1-
866-796-4368.
Syngenta encourages responsible product stewardship to ensure effective long-term
control of the insect and fungal diseases on this label.
THX/MXM/FLD/TBZ/SDX FS
Page 9
(MASTER)
THX/MXM/FLD/TBZ/SDX FS
Page 10
(MASTER)
@@ -470,55 +474,38 @@ Minimum 120-Day
Plantback Interval
Cereal Grains: Barley, Oats,
Rye, Triticale, and Wheat
Peas, Dried Shelled:
Chickpea (Garbanzo Bean),
Field Pea, Lentil, and Pigeon
Pea
Field Pea, Lentil, and
Pigeon Pea
Soybean
Alfalfa
Brassica (Cole) Leafy Vegetables
Brassica &ROH /HDI\9HJHWDEOHV
Cereal Grains (buckwheat, corn,
pearl millet, proso, popcorn, rice
(dry-seeded), sorghum, teosinite,
wild rice
(dry-seeded), sorghum,
teosinite, wild rice)
Cotton
Cucurbit Vegetables
Fruiting Vegetables
&XFXUELW9HJHWDEOHV
)UXLWLQJ9HJHWDEOHV
Globe Artichoke
Leafy Vegetables
Legume Vegetables
(Succulent or Dried)
Leafy 9HJHWDEOHV
/HJXPH9HJHWDEOHV (Succulent
or Dried)
Mint: Peppermint and Spearmint
Oilseeds: Borage, Crambe, Flax
Seed, Mustard Seed, and
Safflower
Peanut
Root Vegetables
5RRW9HJHWDEOHV
Strawberry
Sunflower
Tobacco
All Other Crops
For any other crop, the minimum plant back interval is 120 days from the date the
THX/MXM/FLD/TBZ/SDX FS treated seed was planted. A cover crop other than the
crops listed above that is planted for erosion control or soil improvement may be planted
sooner than the 120 day interval; however, the crop may not be grazed or harvested for
sooner than the 120-day interval; however, the crop may not be grazed or harvested for
food or feed.
@@ -527,17 +514,20 @@ MIXING PROCEDURES
Important: Always re-circulate THX/MXM/FLD/TBZ/SDX FS thoroughly before using.
Consult the manufacturer of the application equipment you plan to use for suitability for
this application and for instructions on operation and calibration of the equipment.
THX/MXM/FLD/TBZ/SDX FS
Page 10
(MASTER)
this application and for instructions on operation and calibration of the equipment.
Follow the manufacturer application instructions for the seed treatment equipment being
used.
Use an EPA approved dye/colorant that imparts an unnatural color to the seed as
required in 40CFR 153.155(c).
Required Dye Statement: Seed treated with this product must be visually identifiable
from untreated seed by the use of an approved colorant or dye to prevent accidental
use of treated seed as food for humans or feed for animals. Refer to 21 CFR, Part 2.25.
Any colorant or dye added to treated seed must be cleared for use in accordance with
40 CFR, Part 153.155(c).
THX/MXM/FLD/TBZ/SDX FS
Page 11
(MASTER)
Apply THX/MXM/FLD/TBZ/SDX FS as a water-based slurry utilizing standard slurry or
direct inject seed treatment equipment which provides uniform seed coverage. Uneven
@@ -569,131 +559,173 @@ at planting. Seed must be completely dry before adding to planter.
SEED BAG LABEL REQUIREMENTS
The Federal Seed Act requires that bags containing treated seeds shall be labeled with
the following statements:
x This seed has been treated with thiamethoxam insecticide and fludioxonil,
mefenoxam, thiabendazole and sedaxane fungicides.
x Do not use for feed, food, or oil purposes.
Use of On-Farm Treated Seed (when treated seed are not for sale or distribution)
Treated seed sold or distributed for a use not permitted by the following labeling does
not qualify as an exempted treated article under 40 CFR 152.25(a) and is therefore sale
or distribution of an unregistered pesticide, pursuant to FIFRA section 12.
In addition, the U.S. Environmental Protection Agency requires the following statements
on bags containing seeds treated with THX/MXM/FLD/TBZ/SDX FS:
x Ground Water Advisory:
THX/MXM/FLD/TBZ/SDX FS
Page 11
(MASTER)
Thiamethoxam has properties and characteristics associated with chemicals
detected in ground water. This chemical may leach into the ground water if used
in areas where soils are permeable, particularly where the water table is shallow.
Mefenoxam is known to leach through soil into ground water under certain
conditions as a result of agricultural use. This chemical may leach into the
ground water if used in areas where soils are permeable, particularly where the
water table is shallow.
x Pollinator Precautions:
Thiamethoxam is highly toxic to bees, and effects are possible as a result of
exposure to translocated residues in blooming crops.
x Excess treated seed may be used for ethanol production only if (1) by-products
are not used for livestock feed and (2) no measurable residues of pesticide
remain in the ethanol by-products that are used in agronomic practice.
x Do not allow children, pets, or livestock to have access to treated seed.
x Store away from feeds and foodstuffs.
x Wear long-sleeved shirt, long pants and chemical resistant gloves when handling
treated seed.
x Treated seeds exposed on soil surface may be hazardous to wildlife. Cover or
collect treated seeds spilled during loading.
x Treated seed must be planted into the soil at a depth greater than 1 inch.
x Dispose of all excess treated seed. Leftover treated seed may be doublesown
around the headland or buried away from water sources in accordance with local
requirements.
x Do not contaminate water bodies when disposing of planting equipment wash
waters.
x Dispose of seed packaging in accordance with local requirements.
x Do not graze or feed livestock on treated areas for 45 days after planting seed
treated with THX/MXM/FLD/TBZ/SDX FS.
x In the event of a crop failure or harvest of a crop grown from
THX/MXM/FLD/TBZ/SDX FS treated seed, the field may be replanted according
to the following schedule.
x Store treated seed away from food and feedstuffs.
x DO NOT allow children, pets, or livestock to have access to treated seed.
x Treated seed are for planting purposes only. DO NOT use for food, feed, or oil
purposes. DO NOT use treated seed for fuel or ethanol production purposes.
x Wear long-sleeved shirt, long pants, sh oes, socks, and chemical-resistant gloves
when handling treated seed.
x DO NOT plant treated seed by broadcasting to the soil surface. Ensure that all
planted seeds are thoroughly incorporated by the planter during planting. Additional
incorporation may be required to thoroughly cover exposed seeds.
THX/MXM/FLD/TBZ/SDX FS
Page 12
(MASTER)
x Treated seed exposed on the soil surface may be hazardous to wildlife. Cover or
collect treated seed spilled during loading and planting (such as in row ends).
x Treated seed must be planted into the soil at a depth greater than 1 inch.
x Manage excess treated seed (e.g., spilled, unused, or expired treated seed) by one
or more of the following methods:
o Collect excess treated seed for reuse for planting.
o Bury excess treated seed (only allowed if totaling 1 pound or less) at least 30 feet
away from bodies of water at a depth of 6 inches or double the planting depth,
whichever is greater.
o Dispose of excess treated seed by placing them in a landfill in accordance with
applicable laws in your state.
o Return excess treated seed to the supplier if permitted by the state.
x DO NOT contaminate bodies of water when disposing of equipment wash water.
x Advisory Dust-Reducing Technique: The use of seed flow lubricants or polymer
coatings may help decrease the amount of dust released during planting. Follow the
recommendations of the planter manufacturer regarding the use of seed flow
lubricants.
Immediate Plantback Minimum 30-Day
Plantback Interval
Minimum 120-Day
Plantback Interval
Cereal Grains: Barley, Oats,
Rye, Triticale, and Wheat
Seed Treatment in Commercial Facilities or Seed Treatment on farm (when
treated seed are to be sold or distributed) – Seed Bag Labeling Requirements
Peas, Dried Shelled:
Chickpea (Garbanzo Bean),
Field Pea, Lentil, and Pigeon
Pea
The Federal Seed Act requires that bags containing treated seed shall be labeled with
the following statements:
x This seed has been treated with thiamethoxam insecticide and fludioxonil,
mefenoxam, sedaxane, and thiabendazole fungicides.
x DO NOT use for food, feed, or oil purposes.
Soybean
Alfalfa
The U.S. Environmental Protection Agency requires that bags containing treated seed
shall be labeled with the following statements. Any seed treated with
THX/MXM/FLD/TBZ/SDX FS that is sold or distributed without these statements or that
is sold or distributed for a use not permitted by the following labeling does not qualify as
an exempted treated article under 40 CFR 152.25(a) and is therefore sale or distribution
of an unregistered pesticide, pursuant to FIFRA section 12(a)(1)(A).
Brassica (Cole) Leafy Vegetables
This seed has been treated with THX/MXM/FLD/TBZ/SDX FS (EPA Reg No. 100-1559)
containing fludioxonil, mefenoxam, sedaxane, thiabendazole, and thiamethoxam. Any
seed treated with THX/MXM/FLD/TBZ/SDX FS that is sold or distributed for a use not
permitted by the following labeling does not qualify as an exempted treated article under
40 CFR 152.25(a) and is therefore sale or distribution of an unregistered pesticide,
pursuant to FIFRA section 12(a)(1)(A).
Cereal Grains (bucvkwheat, corn,
pearl millet, proso, popcorn, rice
(dry-seeded), sorghum, teosinite,
wild rice
Cotton
Cucurbit Vegetables
Fruiting Vegetables
Globe Artichoke
Leafy Vegetables
Legume Vegetables
(Succulent or Dried)
Mint: Peppermint and Spearmint
Oilseeds: Borage, Crambe, Flax
Seed, Mustard Seed, and
Safflower
Peanut
Root Vegetables
Strawberry
Sunflower
Tobacco
All Other Crops
x For any other crop, the minimum plant back interval is 120 days from the date the
THX/MXM/FLD/TBZ/SDX FS treated seed was planted. A cover crop other than
the crops listed above that is planted for erosion control or soil improvement may
be planted sooner than the 120 day interval; however, the crop may not be
grazed or harvested for food or feed.
x Do not use at a rate that will result in more than 0.083 lb thiamethoxam (37.8
grams ai/A) per acre, 0.004 lb fludioxonil (2.0 grams ai/A) per acre and 0.013 lb
mefenoxam (5.7 grams ai/A) per acre per calendar year as a seed treatment
application.
x This seed has been treated with 0.0756 mg ai thiamethoxam, 0.0113 mg
mefenoxam, and 0.0038 mg fludioxonil per seed.
x Do not use more than 0.266 lb ai/A of thiamethoxam per calendar year, including
all thiamethoxam products and application methods (for example, seed
treatment, in-furrow, and foliar).
x Do not apply a neonicotinoid insecticide within 45 days of planting seed treated
with THX/MXM/FLD/TBZ/SDX FS.
x The contents of this bag are for planting purposes only. DO NOT use for food,
feed, or oil purposes. DO NOT use for fuel or ethanol production purposes.
x Store treated seed away from food and feedstuffs.
x DO NOT allow children, pets, or livestock to have access to treated seed.
THX/MXM/FLD/TBZ/SDX FS
Page 13
(MASTER)
x Wear long-sleeved shirt, long pants and chemical-resistant gloves when handling
treated seed.
x DO NOT plant treated seed by broadcasting to the soil surface. Ensure that all
planted seeds are thoroughly incorporated by the planter during planting.
Additional incorporation may be required to thoroughly cover exposed seeds.
x Treated seed exposed on soil surface may be hazardous to wildlife. Cover or
collect treated seed spilled during loading and planting (such as in row ends).
x Treated seed must be planted into the soil at a depth greater than 1 inch.
x Manage excess treated seed (e.g., spilled, unused, or expired treated seed) by
one or more of the following methods:
o Collect excess treated seed for reuse for planting.
o Bury excess treated seed (only allowed if totaling 1 pound or less) at least 30
feet away from bodies of water at a depth of 6 inches or double the planting
depth, whichever is greater.
o Dispose of excess treated seed by placing them in a landfill in accordance
with applicable laws in your state.
o Return excess treated seed to the supplier if permitted by the state.
x DO NOT contaminate water bodies when disposing of planting equipment wash
waters.
x Dispose of seed packaging in accordance with local requirements.
x DO NOT graze or feed livestock on treated areas for 45 days after planting seed
treated with THX/MXM/FLD/TBZ/SDX FS.
x In the event of a crop failure or harvest of a crop grown from
THX/MXM/FLD/TBZ/SDX FS treated seed, the field may be replanted according
to the following schedule.
Immediate Plantback Minimum 30-Day
Plantback Interval
Minimum 120-Day
Plantback Interval
Cereal Grains: Barley,
Oats, Rye, Triticale,
and Wheat
Peas, Dried Shelled:
Chickpea (Garbanzo
Bean), Field Pea,
Lentil, and Pigeon Pea
Soybean
Alfalfa
Brassica &ROH /HDI\9HJHWDEOHV
Cereal Grains (buckwheat, corn,
pearl millet, proso, popcorn, rice
(dry-seeded), sorghum,
teosinite, wild rice)
Cotton
&XFXUELW9HJHWDEOHV
)UXLWLQJ9HJHWDEOHV
Globe Artichoke
Leafy 9HJHWDEOHV
/HJXPH9HJHWDEOHV 6XFFXOHQW
or Dried)
Mint: Peppermint and Spearmint
Oilseeds: Borage, Crambe, Flax
Seed, Mustard Seed, and
Safflower
Peanut
5RRW9HJHWDEOHV
Strawberry
Sunflower
Tobacco
All Other Crops
THX/MXM/FLD/TBZ/SDX FS
Page 14
(MASTER)
x For any other crop, the minimum plant back interval is 120 days from the date the
THX/MXM/FLD/TBZ/SDX FS treated seed was planted. A cover crop other than
the crops listed above that is planted for erosion control or soil improvement may
be planted sooner than the 120-day interval; however, the crop may not be
grazed or harvested for food or feed.
x DO NOT apply more than 0.083 lb/A (37.8 g ai/A) thiamethoxam, 0.004 lb/A (2.0
g ai/A) fludioxonil, and 0.013 lb/A (5.7 g ai/A) mefenoxam per calendar year as a
seed treatment application.
x This seed has been treated with 0.0756 mg ai thiamethoxam, 0.0113 mg
mefenoxam, and 0.0038 mg fludioxonil per seed.
x DO NOT use more than 0.266 lb ai/A of thiamethoxam per calendar year,
including all thiamethoxam products and application methods (for example, seed
treatment, in-furrow, and foliar).
x DO NOT apply a neonicotinoid insecticide within 45 days of planting seed treated
with THX/MXM/FLD/TBZ/SDX FS.
x Non-Target Organism Advisory Statement:
This product may adversely impact non-target organisms feeding on treated
seed. Protect the non-target organisms by following label directions intended to
minimize availability of treated seed to non-target organisms.
x Groundwater Advisory: Mefenoxam is known to leach through soil into
groundwater under certain conditions as a result of agricultural use.
Thiamethoxam has properties and characteristics associated with chemicals
detected in groundwater. These chemicals may leach into the groundwater if
used in areas where soils are permeable, particularly where the water table is
shallow.
x Pollinator Precautions: Thiamethoxam is highly toxic to bees, and effects are
possible as a result of exposure to translocated residues in blooming crops.
x Advisory Dust-Reducing Technique: The use of seed flow lubricants or
polymer coatings may help decrease the amount of dust released during
planting. Follow the recommendations of the planter manufacturer regarding the
use of seed flow lubricants.
x [All seed bag tags must be legible and set in at least 8-point font size.]
USE DIRECTIONS
When applied according to the THX/MXM/FLD/TBZ/SDX FS RATE TABLE,
@@ -704,10 +736,13 @@ corn maggot, three-cornered alfalfa hopper, thrips, white grubs, and wireworm.
THX/MXM/FLD/TBZ/SDX FS provides protection against damping-off and seed borne
rots due to Pythium, Phytophthora, Fusarium, Rhizoctonia species and early season
Phytophthora root rot. THX/MXM/FLD/TBZ/SDX FS also suppresses seed-borne
Sclerotinia and Phomopsis species.
Sclerotinia and Phomopsis species.
THX/MXM/FLD/TBZ/SDX FS
Page 15
(MASTER)
THX/MXM/FLD/TBZ/SDX FS Rate Table
1
THX/MXM/FLD/TBZ/SDX FS Rate Table1
Crop Rate of THX/MXM/FLD/TBZ/SDX FS
Soybean, including
@@ -728,37 +763,31 @@ Thiabendazole 5.0 g
Fludioxonil 2.5 g
Sedaxane 2.5 g
Total = 0.102
Total = 0.102
1The mg ai per seed and fl oz THX/MXM/FLD/TBZ/SDX FS per 100 lb seed rates are based on 3,000
seeds per pound.
2This seed has been treated with 0.0756 mg ai/seed of thiamethoxam, 0.0113 mg ai/seed of mefenoxam,
0.0076 mg ai/seed of thiabendazole, 0.0038 mg ai/seed of fludioxonil, and 0.0038 mg ai/seed of
sedaxane.
USE RESTRICTIONS
x Do not allow children, pets, or livestock to have access to treated seed.
x Do not graze or feed livestock on treated areas for 45 days after planting seed
treated with THX/MXM/FLD/TBZ/SDX FS.
x Do not use at a rate that will result in more than 0.083 lb thiamethoxam (37.8
grams ai/A) per acre, 0.004 lb fludioxonil (2.0 grams ai/A) per acre and 0.013 lb
mefenoxam (5.7 grams ai/A) per acre per calendar year as a seed treatment
application.
x This seed has been treated with 0.0756 mg ai thiamethoxam, 0.0113 mg
mefenoxam, and 0.0038 mg fludioxonil per seed.
x Do not use more than 0.266 lb ai/A of thiamethoxam per calendar year, including
all thiamethoxam products and application methods (for example, seed
treatment, in-furrow, and foliar).
sedaxane.
THX/MXM/FLD/TBZ/SDX FS
Page 14
Page 16
(MASTER)
x Do not apply a neonicotinoid insecticide within 45 days of planting seed treated
USE RESTRICTIONS
x DO NOT allow children, pets, or livestock to have access to treated seed.
x DO NOT graze or feed livestock on treated areas for 45 days after planting seed
treated with THX/MXM/FLD/TBZ/SDX FS.
x DO NOT apply more than 0.083 lb/A (37.8 g ai/A) thiamethoxam, 0.004 lb/A (2.0
g ai/A) fludioxonil, and 0.013 lb/A (5.7 g ai/A) mefenoxam per calendar year as a
seed treatment application.
x This seed has been treated with 0.0756 mg ai thiamethoxam, 0.0113 mg
mefenoxam, and 0.0038 mg fludioxonil per seed.
x DO NOT use more than 0.266 lb ai/A of thiamethoxam per calendar year,
including all thiamethoxam products and application methods (for example, seed
treatment, in-furrow, and foliar).
x DO NOT apply a neonicotinoid insecticide within 45 days of planting seed treated
with THX/MXM/FLD/TBZ/SDX FS.
STORED GRAIN PROTECTION
@@ -773,7 +802,6 @@ If the soybean seed to be treated has existing infestations of stored grain inse
fumigate the seed with a registered product approved for such use prior to treating with
THX/MXM/FLD/TBZ/SDX FS and bagging.
STORAGE AND DISPOSAL
Do not contaminate water, food, or feed by storage, or disposal, or cleaning of
@@ -792,7 +820,12 @@ Wastes resulting from the use of this product may be disposed of on site or at a
approved waste disposal facility. If these wastes cannot be used according to label
instructions, contact your State Pesticide or Environmental Control Agency or the
Hazardous Waste representative at the nearest EPA Regional Office for guidance in
proper disposal methods.
proper disposal methods.
THX/MXM/FLD/TBZ/SDX FS
Page 17
(MASTER)
Container Handling [less than or equal to 5 gallons]
@@ -802,12 +835,7 @@ contents into application equipment or a mix tank and drain for 10 seconds after
begins to drip. Fill the container ¼ full with water and recap. Shake for 10 seconds.
Pour rinsate into application equipment or a mix tank or store rinsate for later use or
disposal. Drain for 10 seconds after the flow begins to drip. Repeat this procedure two
more times. Then offer for recycling if available or puncture and dispose of in a sanitary
THX/MXM/FLD/TBZ/SDX FS
Page 15
(MASTER)
more times. Then offer for recycling if available or puncture and dispose of in a sanitary
landfill, or by incineration, or by other procedures approved by state and local
authorities.
@@ -837,17 +865,23 @@ or by other procedures approved by state and local authorities.
CONTAINER IS NOT SAFE FOR FOOD, FEED, OR DRINKING WATER!
Viton® trademark of E.I. du Pont de Nemours and Company
The ALLIANCE FRAME, the SYNGENTA Logo, and the PURPOSE ICON are
Trademarks of a Syngenta Group Company
©20XX Syngenta
9LWRQ™ is a trademark of The Chemours Company FC, LLC
© 20XX Syngenta
THX/MXM/FLD/TBZ/SDX FS
Page 18
(MASTER)
Manufactured for:
Syngenta Crop Protection, LLC
P. O. Box 18300
Greensboro, North Carolina 27419-8300
THX-MXM-FLD-TBZ-SDX FS 1559 MAS 0616 AMEND 0618 – mar – 06/04/18
000100-01559.20180530.THX-MXM-FLD-TBZ-SDX_FS.AMEND-JUN2018.PDF
THX-MXM-FLD-TBZ-SDX FS 1559 MAS 0616 AMEND 0618-HI – mar – 06/04/18
000100-01559.20180530.THX-MXM-FLD-TBZ-SDX_FS.AMEND-JUN2018-HI.PDF
THX-MXM-FLD-TBZ-SDX FS 1559 MAS 0919 AMEND-B FEB2026-CL – jeb 05/21/2026
000100-01559.20260216B.THX_MXM_FLD_TBZ_SDX_FS.AMEND.0226-CL.PDF