crop-chem-docs/corpus/epa_ppls/100-1262.md

INSPIRE

• EPA Reg No: 100-1262
• Registrant: SYNGENTA CROP PROTECTION, LLC
• Signal word: Warning
• Active ingredients: Difenoconazole (23.2%)
• Label accepted: 2020-03-20
• Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000100-01262-20200320.pdf

---

March 20, 2020 Subject; Dear Ms. Smith; New Use PRIA Unconditional v. 20150320 OFFICE OF CHEMICAL SAFETY AND POLLUTION PREVENTION The application referred to above, submitted under the Federal Insecticide, Fungicide and Rodenticide Act, as amended is acceptable under FIFRA sec 3 (c)(5). You must submit and/or cite all data required for registration/reregistration/registration review of your product when the Agency requires all registrants of similar products to submit such data. A stamped copy of your labeling is enclosed for your records. This labeling supersedes all previously accepted labeling. You must submit one (1) copy of the final printed labeling before you release the product for shipment with the new labeling. In accordance with 40 CFR 152.130(c), you may distribute or sell this product under the previously approved labeling for 18 months from the date of this letter. After 18 months, you may only distribute or sell this product if it bears this new revised labeling or subsequently approved labeling. “To distribute or sell” is defined under FIFRA section 2(gg) and its implementing regulation at 40 CFR 152.3. Should you wish to add/retain a reference to the company’s website on your label, then please be aware that the website becomes labeling under the Federal Insecticide Fungicide and Rodenticide Act and is subject to review by the Agency. If the website is false or misleading, the product would be misbranded and unlawful to sell or distribute under FIFRA section 12(a)(1)(E). 40 CFR 156.10(a)(5) list examples of statements EPA may consider false or misleading. In addition, regardless of whether a website is referenced on your product’s label, claims made on the website may not substantially differ from those claims approved through the registration process. Therefore, should the Agency find or if it is brought to our attention that a website contains false or misleading statements or claims substantially differing from the EPA approved registration, the website will be referred to the EPA’s Office of Enforcement and Compliance. Your release for shipment of the product constitutes acceptance of these conditions. If these conditions are not complied with, the registration will be subject to cancellation in accordance Nakia Smith Regulatory Product Manager Syngenta Crop Protection, LLC P. O. Box 18300 Greensboro, NC 27419 PRIA Label Amendment - Adding new uses in/on vegetable, leaves of root and tuber, group 2 and vegetable, root, subgroup 1A Product Name; Inspire EPA Registration Number; 100-1262 Application Date; 7/27/2018 Decision Number; 543308 UNITED STATES ENVIRONMENTAL PROTECTION AGENCY WASHINGTON, DC 20460/ A \ w

Sincerely, Enclosure -stamped “accepted” label Cynthia Giles-Parker, Chief Fungicide Branch Registration Division (7505P) with FIFRA section 6. If you have any questions, please contact Nathan Mellor by phone at 703- 347-8562, or via email at mellor.nathan@epa.gov. Page 2 of 2 EPAReg. No. 100-1262 Decision No. 543308

[MASTER LABEL] DIFENOCONAZOLE | GROUP FUNGICIDE Inspire® Fungicide KEEP OUT OF REACH OF CHILDREN. WARNING/AVISO EPA Reg. No. 100-1262 ACCEPTEDEPA Est. Net Contents 3 Inspire is formulated as an emulsifiable concentrate (EC) containing 2.08 lb ai/gal of difenoconazole. Si usted no entiende la etiqueta, busque a alguien para que se la explique a usted en details. (If you do not understand the label, find someone to explain it to you in detail.) CAS No. 119446-68-3 Contains petroleum distillates See additional precautionary statements and directions for use inside booklet. See First Aid statement inside booklet or on container label. ..23.2% 76.8% 100.0% Active Ingredient: Difenoconazole:.... Other Ingredients: Total: Mar 20, 2020 Under the Federal InsecliiAie, Fungicide Sii'id Rodentbcitie Act as arr^encted, lor the pesticide registered under EPA Reg. No. .,00.1262

If in eyes If swallowed If inhaled PRECAUTIONARY STATEMENTS Hazards to Humans and Domestic Animals WARNING/AVISO If on skin or clothing Causes substantial but temporary eye injury. DO NOT get in eyes or on clothing. Harmful if swallowed. Avoid contact with skin, eyes, or clothing. Wash thoroughly with soap and water after handling and before eating, drinking, chewing gum. using tobacco or using the toilet. Remove and wash contaminated clothing before reuse. NOTE TO PHYSICIAN Contains petroleum distillates - vomiting may cause aspiration pneumonia._______ Have the product container or label with you when calling a poison control center or doctor, or going for treatment. FIRST AID_______________ • Hold eye open and rinse slowly and gently with water for 15-20 minutes. Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye. • Call a poison control center or doctor for treatment advice._____ • Immediately call a poison control center or doctor. • Do not induce vomiting unless told to do so by a poison control center or doctor. • Do not give any liquid to the person. • Do not give anything by mouth to an unconscious person.______ • Take off contaminated clothing. • Rinse skin immediately with plenty of water for 15-20 minutes. • Call a poison control center or doctor for treatment advice._____ • Move person to fresh air. • If person is not breathing, call 911 or an ambulance, then give artificial respiration, preferably mouth-to-mouth if possible. • Call a poison control center or doctor for further treatment advice. Inspire Page 2 HOT LINE NUMBER For 24-Hour Medical Emergency Assistance (Human or Animal) Or Chemical Emergency Assistance (Spill. Leak, Fire or Accident) Call 1-800-888-8372

Personal Protective Equipment (PPE) Mixers, loaders, applicators and all other handlers must wear: User Safety Requirements Engineering Controls User Safety Recommendations Users should: Environmental Hazards When handlers use closed systems, enclosed cabs, or aircraft in a manner that meets the requirements listed in the Worker Protection Standard (WPS) for agricultural pesticides [40 CFR 170.240(d)(4-6)], the handler PPE requirements may be reduced or modified as specified in the WPS. This pesticide is toxic to fish, mammals, and aquatic invertebrates. Drift and runoff may be hazardous to aquatic estuarine/marine organisms in water adjacent to treated areas. DO NOT apply directly to water, or to areas where surface water is present or to intertidal areas below the mean high water mark. DO NOT contaminate water when disposing of equipment washwater or rinsate. • Wash hands before eating, drinking, chewing gum, using tobacco, or using the toilet. • Remove clothing/PPE immediately if pesticide gets inside. Then wash thoroughly and put on clean clothing. • Remove PPE immediately after handling this product. Wash the outside of gloves before removing. As soon as possible, wash thoroughly and change into clean clothing. Follow manufacturer’s instructions for cleaning/maintaining PPE. If no such instructions for washables exist, use detergent and hot water. Keep and wash PPE separately from other laundry. DO NOT discharge effluent containing this product into lakes, streams, ponds, estuaries, oceans, or other waters unless in accordance with the requirements of a National Pollutant Discharge Elimination System (NPDES) permit and the permitting authority has been notified in writing prior to discharge. DO NOT discharge effluent • Chemical-resistant gloves including: barrier laminate, nitrile rubber > 14 mils, neoprene rubber > 14 mils, or Viton® > 14 mils • Protective eyewear • Long-sleeved shirt and long pants • Socks and shoes Inspire Page 3

Surface Water Advisory Physical or Chemical Hazards DO NOT use or store near heat or open flame. containing this product to sewer systems without previously notifying the local sewage treatment plant authority. For guidance, contact your State Water Board or regional office of the EPA. This product may impact surface water quality due to runoff of rain water. This is especially true for poorly draining soils and soils with shallow ground water. This product may contaminate water through drift or spray in wind. This product has a potential for runoff for several months or more after application. A level, well-maintained vegetative buffer strip between areas to which this product is applied and surface water features including ponds, streams, and springs will reduce the potential for contamination of water from runoff water and sediment. Runoff of this product will be reduced by avoiding applications when rainfall is expected to occur within 48 hours. Sound erosion control practices will reduce this product’s potential to reach aquatic sediment via runoff. Inspire Page 4

CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY 1 NOTICE: Read the entire Directions for Use and Conditions of Sale and Limitation of Warranty and Liability before buying or using this product. If the terms are not acceptable, return the product at once, unopened, and the purchase price will be refunded. The Directions for Use of this product must be followed carefully. It is impossible to eliminate all risks inherently associated with the use of this product. Crop injury ineffectiveness or other unintended consequences may result because of such factors as manner of use or application, weather or crop conditions, presence of other materials or other influencing factors in the use of the product, which are beyond the control of SYNGENTA CROP PROTECTION. LLC or Seller. To the extent permitted by applicable law. Buyer and User agree to hold SYNGENTA and Seller harmless for any claims relating to such factors. SYNGENTA and Seller offer this product, and Buyer and User accept it. subject to the foregoing Conditions of Sale and Limitation of Warranty and Liability, which may not be modified except by written agreement signed by a duly authorized representative of SYNGENTA. SYNGENTA warrants that this product conforms to the chemical description on the label and is reasonably fit for the purposes stated in the Directions for Use. subject to the inherent risks referred to above, when used in accordance with directions under normal use conditions. To the extent permitted by applicable law: (1) this warranty does not extend to the use of the product contrary to label instructions, or under conditions not reasonably foreseeable to or beyond the control of Seller or SYNGENTA, and (2) Buyer and User assume the risk of any such use. TO THE EXTENT PERMITTED BY APPLICABLE LAW. SYNGENTA MAKES NO WARRANTIES OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE NOR ANY OTHER EXPRESS OR IMPLIED WARRANTY EXCEPT AS WARRANTED BY THIS LABEL. To the extent permitted by applicable law. in no event shall SYNGENTA be liable for any incidental, consequential or special damages resulting from the use or handling of this product. TO THE EXTENT PERMITTED BY APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE USER OR BUYER, AND THE EXCLUSIVE LIABILITY OF SYNGENTA AND SELLER FOR ANY AND ALL CLAIMS, LOSSES, INJURIES OR DAMAGES (INCLUDING CLAIMS BASED ON BREACH OF WARRANTY, CONTRACT, NEGLIGENCE, TORT, STRICT LIABILITY OR OTHERWISE) RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, SHALL BE THE RETURN OF THE PURCHASE PRICE OF THE PRODUCT OR, AT THE ELECTION OF SYNGENTA OR SELLER, THE REPLACEMENT OF THE PRODUCT. Inspire Page 5

DIRECTIONS FOR USE AGRICULTURAL USE REQUIREMENTS J NON-AGRICULTURAL USE REQUIREMENTS Keep unprotected persons out of treated areas until sprays have dried. DO NOT enter or allow worker entry into treated areas during the restricted-entry interval (REI) of 12 hours. DO NOT apply this product in a way that will contact workers or other persons, either directly or through drift. Only protected handlers may be in the area during application. For any requirements specific to your State or Tribe, consult the agency responsible for pesticide regulation. Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR part 170. This Standard contains requirements for the protection of agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of agricultural pesticides. It contains requirements for training, decontamination notification, and emergency assistance. It also contains specific instructions and exceptions pertaining to the statements on this label about personal protective equipment (PPE) and restricted-entry interval. The requirements in this box only apply to uses of this product that are covered by the Worker Protection Standard. It is a violation of Federal Law to use this product in a manner inconsistent with its labeling. • Chemical-resistant gloves including: barrier laminate, butyl rubber greater than or equal to 14 mils, nitrile rubber greater than 14 mils, or Viton greater than 14 mils • Protective eyewear • Coveralls • Socks and shoes The requirements in this box apply to uses of this product that are NOT within the scope of the Worker Protection Standard for agricultural pesticides (40 CFR Part 170). The WPS applies when this product is used to produce agricultural plants on farms, forests, nurseries, or greenhouses. PPE required for early entry to treated areas that is permitted under the Worker Protection Standard and that involves contact with anything that has been treated, including plants, soil, or water is: Inspire Page 6

PRODUCT INFORMATION PRODUCT USE INSTRUCTIONS Inspire is a broad spectrum fungicide with systemic and curative properties for the control of many important plant diseases. Inspire may be applied as a foliar spray in alternating spray programs or in tank mixes with other crop protection products. All applications must be made according to the use directions that follow. Efficacy: Under certain conditions conducive to extended infection periods, use another registered fungicide for additional applications if maximum amount of Inspire has been used. If resistant isolates to Group 3 fungicides are present, efficacy can be reduced. Under high disease pressure, use the highest rate and shortest interval. Application: Thorough coverage is necessary to provide good disease control. Make up no more spray solution than is needed for application. Avoid spray overlap, as crop injury may occur. FAILURE TO FOLLOW DIRECTIONS AND PRECAUTIONS ON THIS LABEL MAY RESULT IN CROP INJURY, POOR DISEASE CONTROL, OR ILLEGAL RESIDUES. Inspire Page 7

Rotational Crops: Please see the table below for the crop rotational restrictions. Rotational Crop 0 days All other crops intended for food and feed Crop Tolerance: Plant tolerance has been found acceptable for all crops on the label; however, not all possible tank-mix combinations have been tested under all conditions. Planting Time From Last Inspire Application Inspire Page 8 30 days 60 days Artichoke. Globe________________________________ Bean and Pea, Dried Shelled Subgroup 6C___________ Berry, Bushberry Subgroup 13-07B_________________ Berry, Low Growing Subgroup 13-07G _______________ Brassica (Cole) Head and Stem vegetables Group 5-16 Brassica (Cole) Leafy greens Subgroup 4-1 6B_________ Bulb vegetables, bulb onion Subgroup 3-07A and green onion Subgroup 3-07B____________________________ Carrots________________________________________ Chickpeas_____________________________________ Citrus fruit Crop Group 10-10 ______________________ Cotton Subgroup 20C____________________________ Cucurbit vegetables Crop Group 9__________________ Fruit, small, vine climbing Subgroup 13-07F, except fuzzy kiwifruit________________________________________ Fruiting vegetables Crop Group 8-10 ________________ Ginseng_______________________________________ Guava________________________________________ Kohlrabi_______________________________________ Leaves of Root and Tuber Vegetables Crop Group 2 Papaya________________________________________ Pome fruit Crop Group 11-10 ______________________ Potatoes______________________________________ Rapeseed Subgroup 20A _________________________ Rice__________________________________________ Root vegetable Subgroup 1A ______________________ Soybeans______________________________________ Stonefruit Crop Group 12-12 ______________________ Strawberry_____________________________________ Sugar beets____________________________________ Tomatoes and tomatillos__________________________ Tree nuts Crop Group 14-12 _______________________ Tuberous and corm vegetable subgroup 1C___________ Watercress____________________________________ Wild rice_______________________________________ Cereals (wheat, barley, triticale, oats and rye)

Spray Drift Management: MANDATORY SPRAY DRIFT Aerial Applications Groundboom Applications When possible, it is recommended to test the combinations on a small portion of the crop to ensure a phytotoxic response will not occur as a result of application. • Apply with the nozzle height recommended by the manufacturer, but no more than 3 feet above the ground or crop canopy. • For all applications, applicators are required to use a medium to ultra coarse spray droplet size (ASABE S572.1). • DO NOT apply when wind speeds exceed 10 miles per hour at the application site. • DO NOT apply during temperature inversions. Boomless Ground Applications • Applicators are required to use a medium or coarser droplet size (ASABE S572.1) for all applications. • DO NOT apply when wind speeds exceed 10 miles per hour at the application site. • DO NOT apply during temperature inversions. • DO NOT release spray at a height greater than 10 ft above the vegetative canopy, unless a greater application height is necessary for pilot safety. • For all applications, applicators are required to use a medium to ultra coarse spray droplet size (ASABE S572.1). • The boom length must not exceed 65% of the wingspan for airplanes or 75% of the rotor blade diameter for helicopters. • Applicators must use % swath displacement upwind at the downwind edge of the field. • Nozzles must be oriented so the spray is directed toward the back of the aircraft. • DO NOT apply when wind speeds exceed 10 miles per hour at the application site. • DO NOT apply during temperature inversions. Inspire Page 9

SPRAY DRIFT ADVISORIES IMPORTANCE OF DROPLET SIZE BOOM HEIGHT - Ground Boom THE APPLICATOR IS RESPONSIBLE FOR AVOIDING OFF-SITE SPRAY DRIFT. BE AWARE OF NEARBY NON-TARGET SITES AND ENVIRONMENTAL CONDITIONS. Inspire Page 10 An effective way to reduce spray drift is to apply large droplets. Use the largest droplets that provide target pest control. While applying larger droplets will reduce spray drift, the potential for drift will be greater if applications are made improperly or under unfavorable environmental conditions. Controlling Droplet Size - Groundboom • Volume - Increasing the spray volume so that larger droplets are produced will reduce spray drift. Use the highest practical spray volume for the application. If a greater spray volume is needed, consider using a nozzle with a higher flow rate. • Pressure - Use the lowest spray pressure recommended for the nozzle to produce the target spray volume and droplet size. For many nozzle types, lower pressure produces larger droplets. When higher flow rates are needed, use higher rate nozzles instead of increasing pressure. • Spray Nozzle - Use a spray nozzle that is designed for the intended application. Consider using nozzles designed to reduce drift. Controlling Droplet Size - Aircraft • Adjust Nozzles - Follow nozzle manufacturers recommendations for setting up nozzles. Generally, to reduce fine droplets, nozzles should be oriented parallel with the airflow in flight. Use the lowest boom height that is compatible with the spray nozzles that will provide uniform coverage. For ground equipment, the boom should remain level with the crop and have minimal bounce. RELEASE HEIGHT - Aircraft Higher release heights increase the potential for spray drift. When applying aerially to crops, do not release spray at a height greater than 10 ft above the crop canopy, unless a greater application height is necessary for pilot safety. SHIELDED SPRAYERS Shielding the boom or individual nozzles can reduce spray drift. Consider using shielded sprayers. Verify that the shields are not interfering with the uniform deposition of the spray on the target area.

WIND TEMPERATURE AND HUMIDITY RESISTANCE MANAGEMENT DIFENOCONAZOLE | GROUP FUNGICIDE DO NOT apply to plants grown for transplanting purposes. To delay fungicide resistance, take one or more of the following steps: 3 Inspire Page 11 • Rotate the use of Inspire or other Group 3 fungicides within a growing season sequence with different groups that control the same pathogens. IPM: Integrate Inspire into an overall disease and pest management strategy (IPM) whenever the use of a fungicide is required. Follow cultural practices known to reduce disease development. Consult your local agricultural authorities for additional IPM strategies established for your area. Inspire may be used in State Agricultural Extension advisory (disease forecasting) programs which direct application timing based on environmental factors favorable for disease development. Drift potential is high during a temperature inversion. Temperature inversions are characterized by increasing temperature with altitude and are common on nights with limited cloud cover and light to no wind. The presence of an inversion can be indicated by ground fog or by the movement of smoke from a ground source or an aircraft smoke generator. Smoke that layers and moves laterally in a concentrated cloud (under low wind conditions) indicates an inversion, while smoke that moves upward and rapidly dissipates indicates good vertical air mixing. Avoid applications during temperature inversions. Drift potential generally increases with wind speed. AVOID APPLICATIONS DURING GUSTY WIND CONDITIONS. Note: Local terrain can influence wind patterns. Every applicator needs to be familiar with local wind patterns and how they affect spray drift. When making applications in hot and dry conditions, use larger droplets to reduce effects of evaporation. TEMPERATURE INVERSIONS For resistance management. Inspire contains a Group 3 fungicide. Any fungal population may contain individuals naturally resistant to Inspire and other Group 3 fungicides. A gradual or total loss of pest control may occur over time if these fungicides are used repeatedly in the same fields. Follow appropriate resistance-management strategies.

1 SPRAY EQUIPMENT (1) (2) For more information on spray equipment and calibration, consult sprayer manufacturers and state directions. For specific local directions and spray schedules, consult the current state agricultural directions. • Use tank mixtures with fungicides from a different group that are equally effective on the target pest when such use is permitted. Use at least the minimum application rate as labeled by the manufacturer. • Adopt an integrated disease management program for fungicide use that includes scouting, uses historical information related to pesticide use, and crop rotation, and which considers host plant resistance, impact of environmental conditions on disease development, disease thresholds, as well as cultural biological and other chemical control practices. • Where possible, make use of predictive disease models to effectively time fungicide applications. Note that using predictive models alone is not sufficient to manage resistance. • Monitor treated fungal populations for resistance development. • Contact your local extension specialist or certified crop advisor for any additional pesticide resistance-management and/or IPM directions for specific crops and pathogens. • For further information or to report suspected resistance contact Syngenta Crop Protection at 1-866-796-4368. You can also contact your pesticide distributor or university extension specialist to report resistance. Nozzles • Equip sprayers with nozzles that provide accurate and uniform application. • Use the same size nozzles uniformly spaced across the boom. • Calibrate sprayer before use. • Use screens to protect the pump and to prevent nozzles from clogging. • On suction side of pump use screens that are 16-mesh or coarser. • DO NOT place a screen in the recirculation line. • Use 50-mesh or coarser screens between the pump and boom, and where required, at the nozzles. • Check nozzle manufacturer’s directions. Inspire Page 12 Pump • Use a pump with capacity to: Maintain sufficient pressure at the nozzle tip to give the required flow rate and droplet size to provide acceptable coverage of the target crop. Provide sufficient agitation in tank to keep mixture in suspension - this requires recirculation of 10% of tank volume per minute. • Use a jet agitator or liquid sparge tube for agitation. • DO NOT air sparge.

MIXING INSTRUCTIONS J Mixing in the Spray Tank Inspire + Tank Mixtures: Inspire is usually compatible with tank-mix partners. To determine the physical compatibility of Inspire with other products, use a jar test. Using a quart jar, add the proportionate amounts of the products to 1 qt of water. Add wettable powders and water dispersible granular products first, then liquid flowables and emulsifiable concentrates last. After thoroughly mixing, let stand for at least 5 minutes. If the combination remains mixed or can be remixed readily, it is physically compatible. Once compatibility has been proven, use the same procedure for adding required ingredients to the spray tank. • Prepare no more spray mixture than is required for the immediate operation. • Thoroughly clean spray equipment before using this product. • Agitate the spray solution before and during application. • Rinse spray tank thoroughly with clean water after each day’s use and dispose of pesticide rinsate by application to an already treated area. Inspire Alone (no tank mix): • Add %-% of the required amount of water to the spray or mixing tank. • With the agitator running, add Inspire to the tank. • Continue agitation while adding the remainder of the water. • Begin application of the spray solution after Inspire has completely dispersed into the mix water. • Maintain agitation until all of the mixture has been sprayed. • It is the pesticide user’s responsibility to ensure that all products are registered for the intended use. Read and follow the applicable restrictions and limitations and directions for use on all product labels involved in tank mixing. Users must follow the most restrictive directions for use and precautionary statements of each product in the tank mixture. • Add %-% of the required amount of water to the spray or mixing tank. • With the agitator running, add the tank-mix partner(s) into the tank in the same order as described above. • Allow the material to completely dissolve and disperse into the mix water. Continue agitation while adding the remainder of the water and Inspire to the spray tank. • Allow Inspire to completely disperse. • Spray the mixture with the agitator running. • Observe all directions for use. crops/sites, use rates, dilution ratios, precautions, and limitations which appear on the tank mix product label. • Label dosage rate must not be exceeded, and the most restrictive label precautions and limitations must be followed. • This product must not be mixed with any product which prohibits such mixing. Inspire Page 13

APPLICATION PROCEDURES Operating Instructions

1. The system must contain a functional check-valve, vacuum relief valve, and low pressure drain appropriately located on the irrigation pipeline to prevent water­ source contamination from backflow. Inspire Page 14 Application Through Irrigation Systems (Chemigation) • Use only on crops for which chemigation is specified on this label. • Apply this product only through center pivot, solid set. hand move, or moving wheel irrigation systems. DO NOT apply this product through any other type of irrigation system. • Crop injury, lack of effectiveness, or illegal pesticide residues in the crop can result from non-uniform distribution of treated water. • Apply in 0.125-0.25 inches/A of water. Excessive water may reduce efficacy. • If you have questions about calibration, contact State Extension Service specialists, equipment manufacturers, or other experts. • DO NOT connect an irrigation system (including greenhouse systems) used for pesticide application to a public water system, unless the pesticide label-prescribed safety devices for public water systems are in place. • A person knowledgeable of the chemigation system and responsible for its operation, or under the supervision of the responsible person, shall shut the system down and make necessary adjustments if the need arises. Ground Application: • Apply in a minimum of 10 gal of water per acre, unless specified otherwise. Note: DO NOT inject Inspire at full strength or deterioration of valves and seals may occur. Use a dilution ratio of at least 10 parts water to 1 part Inspire. Inspire is corrosive to many seal materials. Leather seals are best. EPDM or silicone rubber seals can be used, but must be replaced once a year. DO NOT use Viton, Buna-N, Neoprene, or PVC seals. Aerial Application: • Use only on crops where aerial applications are indicated. • Apply in a minimum of 5 gal of water per acre, unless specified otherwise. For pome fruit apply in a minimum of 10 gal of water per acre. • DO NOT apply under conditions when uniform coverage cannot be obtained or when excessive spray drift may occur. • DO NOT apply directly to humans or animals.

3. J

7. DO NOT apply when wind speed favors drift beyond the area intended. Center Pivot Irrigation Equipment The system must contain functional interlocking controls to automatically shut off the pesticide injection pump when the water pump motor stops. The pesticide injection pipeline must also contain a functional, normally closed solenoid-operated valve located on the intake side of the injection pump and connected to the system interlock to prevent fluid from being withdrawn from the supply tank when the irrigation system is either automatically or manually shut down. Systems must use a metering pump, for example, a positive displacement injection pump (e.g., diaphragm pump), effectively designed and constructed of materials that are compatible with pesticides and capable of being fitted with a system interlock. The irrigation line or water pump must include a functional pressure switch which will stop the water pump motor when the water pressure decreases to the point where pesticide distribution is adversely affected. Notes: (1) Use only with drive systems which provide uniform water distribution. (2) DO NOT use end guns when chemigating Inspire through center pivot systems because of non-uniform application. • Determine the size of the area to be treated. • Determine the time required to apply 78-% inch of water over the area to be treated when the system and injection equipment are operated at normal pressures as directed by the equipment manufacturer. When applying Inspire through irrigation equipment use the lowest obtainable water volume while maintaining uniform distribution. Run the system at 80-95% of the manufacturer’s rated capacity. • Using water, determine the injection pump output when operated at normal line pressure. • Determine the amount of Inspire required to treat the area covered by the irrigation system. • Add the required amount of Inspire and sufficient water to meet the injection time requirements to the solution tank. • Make sure the system is fully charged with water before starting injection of the Inspire solution. Time the injection to last at least as long as it takes to bring the system to full pressure. • Maintain constant solution tank agitation during the injection period. The pesticide injection pipeline must contain a functional, automatic, quick­ closing check-valve to prevent the flow of fluid back toward the injection pump. Inspire Page 15

Solid Set, Hand Move, and Moving Wheel Irrigation Equipment SPECIFIC INSTRUCTIONS FOR PUBLIC WATER SYSTEMS 1. 2. 3. 4. 5. The system must contain functional interlocking controls to automatically shut off the pesticide injection pump when the water pump motor stops, or in cases Inspire Page 16 Chemigation systems connected to public water systems must contain a functional, reduced-pressure zone, back-flow preventer (RPZ) or the functional equivalent in the water supply line upstream from the point of pesticide introduction. As an option to the RPZ, the water from the public water system must be discharged into a reservoir tank prior to pesticide introduction. There shall be a complete physical break (air gap) between the outlet end of the fill pipe and the top or overflow rim of the reservoir tank of at least twice the inside diameter of the fill pipe. The pesticide injection pipeline must contain a functional, normally closed, solenoid-operated valve located on the intake side of the injection pump and connected to the system interlock to prevent fluid from being withdrawn from the supply tank when the irrigation system is either automatically or manually shut down. The pesticide injection pipeline must contain a functional, automatic, quick­ closing check valve to prevent the flow of fluid back toward the injection pump. • Determine the acreage covered by the sprinklers. • Fill injector solution tank with water and adjust flow rate to use the contents over a 20 to 30-minute interval. When applying Inspire through irrigation equipment use the lowest obtainable water volume while maintaining uniform distribution. • Determine the amount of Inspire required to treat the area covered by the irrigation system. • Add the required amount of Inspire into the same quantity of water used to calibrate the injection period. • Operate the system at the same pressure and time interval established during the calibration. • Stop injection equipment after treatment is completed. Continue to operate the system until the Inspire solution has cleared the last sprinkler head. Public water system means a system for the provision to the public of piped water for human consumption if such system has at least 15 service connections or regularly serves an average of at least 25 individuals daily at least 60 days out of the year. • Continue to operate the system until the Inspire solution has cleared the sprinkler head.

7. DO NOT apply when wind speed favors drift beyond the area intended for treatment. Systems must use a metering pump, including a positive displacement injection pump (e.g., diaphragm pump) effectively designed and constructed of materials that are compatible with pesticides and capable of being fitted with a system interlock. where there is no water pump, when the water pressure decreases to the point where pesticide distribution is adversely affected. Inspire Page 17

SPECIFIC USE DIRECTIONS If monitoring or history indicates the presence of Alternaria, apply 7 fl oz/A of Inspire in the late spring (mid-April to beginning of May) and then repeat the treatment 2-3 weeks later. For blossom blight, begin applications at early bloom and continue through petal fall. Inspire Page 18 Optional language if label has a rate range and a single interval: If disease pressure is high, use the highest rate. Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval. Remarks Begin applications prior to disease onset when conditions are conducive for disease. Apply Inspire on a 14- to 21-day schedule making no more than 2 sequential applications before alternating to another fungicide with a different mode of action. Use Rate fl oz product/A (lb ai) Optional language if label has a rate range and interval range: If disease pressure is high, use I the shortest interval and highest rate._ Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by either ground or aerial application. Use a minimum of 15 gal/A of water for ground applications. For aerial applications, use a minimum of 10 gal/A of water.________________________________ Specific Use Restrictions:

1. DO NOT apply more than 28 fl oz/A/year of Inspire.
2. DO NOT apply more than 7 fl oz per application (0.114 lb ai of difenoconazole).
3. DO NOT make more than 4 applications per year at the maximum application rate.
4. Minimum Application Interval: 14 days
5. DO NOT apply more than 0.46 lb ai/A/year of difenoconazole.
6. DO NOT apply within 14 days of harvest (14-day PHI). 5-7 (0.08 - 0.114) Crop Almonds [Not for use in California] Target Diseases Alternaria leafspot (A. alternate) Anthracnose {Colletotrichum. acutatum) Blossom Blight Brown rot {Monillnia spp.) Brown rot/hull rot {Monillnia spp.) Powdery mildew {Podosphaera tridactyla, Sphaerotheca pannosa) Scab {Venturia carpophilia) Shot hole {Wilsonmyces carpophilus)

Inspire Page 19 Specific Use Restrictions:

1. DO NOT apply more than 28 ft oz/A/year of Inspire.
2. DO NOT apply more than 7 fl oz per application {0.114 lb ai of difenoconazole).
3. DO NOT make more than 4 applications per year.
4. Minimum Application Interval: 14 days
5. DO NOT apply more than 0.46 lb ai/A/year of difenoconazole.
6. DO NOT apply Inspire within 3 days of harvest (3-day PHI). _Remarks Begin applications prior to disease onset when conditions are conducive for disease. Apply Inspire on a 14-day schedule making no more than 2 sequential applications before alternating to another fungicide with a different mode of action. Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by ground, chemigation, or aerial application. For ground applications, apply in 50- 200 gallons of water per acre to obtain coverage without excessive runoff. For aerial applications, use a minimum of 10 gal/A of water. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy. Use Rate fl oz product/A (lb ai) 7 (0.114) _______Crop Artichoke, Globe [Not for use in California] Target Diseases Ramularia leaf spot Ramularia bud spot (R. cynarae)

(0.114) See complete list below. Remarks Begin applications prior to disease onset when conditions are conducive for disease. Apply Inspire on a 14-day schedule making no more than 2 sequential applications before alternating to another fungicide with a different mode of action. Crop Bean and Pea, Dried Shelled (except soybean) Subgroup 6C [Not for use in California] To be grown for bean, dried seed only. Phaseolus Vigna Pisum Lupinus See specific Directions for soybeans and chickpea._____________________________|____________________________________________ Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by ground, chemigation, or aerial application. Use a minimum of 15 gal/A of water for ground applications. For aerial applications, use a minimum of 10 gal/A of water. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy._____________________________________________________________________________ Complete List of Bean and Pea, dried shelled (except soybean) - Subgroup 6C: Dried cultivars of bean (Lupinus); bean (Phaseolus) (includes field bean, kidney bean, lima bean, navy bean, pinto bean, tepary bean); bean (Vigna) (includes adzuki bean, blackeyed pea, catjang, cowpea, crowder pea, moth bean, mung bean, rice bean, southern pea, urd bean); broad bean; guar; lablab bean; lentil; pea (Pisum) (includes field pea); pigeon pea_________________ Specific Use Restrictions:

1. DO NOT apply more than 28 fl oz/A/year of Inspire.
2. DO NOT apply more than 14 fl oz/A/year of Inspire (0.23 lb ai/A/year) for pea vines and hay.
3. DO NOT apply more than 7 fl oz per application (0.114 lb ai of difenoconazole).
4. DO NOT make more than 4 applications per year.
5. Minimum Application Interval: 14 days
6. DO NOT apply more than 0.46 lb ai/A/year of difenoconazole.
7. DO NOT feed or harvest cowpeas forage and hay.
8. DO NOT apply Inspire within 14 days of harvest (14-day PHI). Use Rate fl oz product/A (lb ai) 7 Inspire Page 20 Target Diseases Anthranose {Colletotrichum lindemuthianum} Alternaria leaf spot (A. alternate) Alternaria blight {Alternaria spp.) Ascochyta leaf and pod spot {Ascochyta spp.) Ascochyta blight {Mycosphaerella pinodes) Cercospora leaf spot {Cercospora cruenta}

(0.114) Blueberry For Monilinia and mummyberry, apply at or near flower bud swell and again at leaf bud swelling. For other diseases, apply during early bloom. Apply Inspire on a 7- to 14-day schedule making no more than 2 sequential applications before alternating to another fungicide with a different mode of action. [Not for use in California] Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by ground or aerial application. Use a minimum of 15 gal/A of water for ground applications. For aerial applications, use a minimum of 10 gal/A of water._________________________ Complete List of Bushberry Subgroup: Aronia berry; blueberry, highbush; blueberry, lowbush; buffalo currant; Chilean guava; cranberry, highbush; currant, black; currant, red; elderberry; European barberry; gooseberry; honeysuckle, edible; huckleberry; jostaberry; Juneberry (Saskatoon berry); lingonberry; native currant; salal; sea buckthorn; cultivars, varieties, and/or hybrids of these_____________________ Specific Use Restrictions:

1. DO NOT apply more than 28 ft oz/A/year of Inspire.
2. DO NOT apply more than 7 fl oz per application (0.114 lb ai of difenoconazole).
3. DO NOT make more than 4 applications per year.
4. Minimum Application Interval: 7 days
5. DO NOT apply more than 0.46 lb ai/A/year of difenoconazole.
6. DO NOT apply Inspire within 7 days of harvest (7-dav PHI). Use Rate fl oz product/A (lb ai) 7 _Remarks Begin applications prior to disease onset when conditions are conducive for disease. Inspire Page 21 Target Diseases Powdery mildew {Microsphaera alni) Anthracnose {Colletotrichum spp.) Septoria leaf spot (S. albopunctata} Alternaria leaf spot {A.tenuissima) Leaf rust {Pucciniastrum vaccinii} Monilinia blight and Mummyberry blight {M. vaccinii- corymbosis) _______Crop Berry Bushberry Subgroup 13-07B

strawberry See additional crops below. Leaf spot {Cercospora fragariae} Powdery mildew {Sphaerotheca macularis) Leaf rust {Phragmidium potentillae) Optional language if label has a rate range and a single interval'. If disease pressure is high, use the highest rate. Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval. [Not for use in California] Remarks Begin applications prior to disease onset when conditions are conducive for disease. Apply Inspire on a 7- to 14-day schedule making no more than 2 sequential applications before alternating to another fungicide with a different mode of action. Optional language if label has a rate range and interval range'. If disease pressure is high, use the shortest interval and highest rate. Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by ground, chemigation or aerial application. Use a minimum of 15 gal/A of water for ground applications. For aerial applications, use a minimum of 10 gal/A of water. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy.________________________________________ Additional Low Growing Berries: Bearberry, Bilberry, Cloudberry, Muntries, Partridgeberry, Strawberry including all cultivars and/or hybrids of these____________________________________ Specific Use Restrictions:

1. DO NOT apply more than 28 fl oz/A/year of Inspire.
2. DO NOT apply more than 7 fl oz per application {0.114 lb ai of difenoconazole).
3. DO NOT make more than 4 applications per year at the maximum application rate.
4. Minimum Application Interval: 7 days
5. DO NOT apply more than 0.46 lb ai/A/year of difenoconazole.
6. Inspire may be applied up to the day of harvest (0-day PHI). See separate instructions for cranberry. Crop Berry, Low Growing Subgroup 13-07G Inspire Page 22 Target Diseases Anthracnose {Colletotrichum acutatum) Use Rate fl oz product/A (lb ai) 5.5-7 (0.09-0.114)

Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval. Remarks Begin applications prior to disease onset when conditions are conducive for disease. Apply Inspire on a 7- to 10-day schedule making no more than 2 sequential applications before alternating to another fungicide with a different mode of action. Optional language if label has a rate range and a single interval: If disease pressure is high, use the highest rate. Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and highest rate. Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by either ground, chemigation, or aerial application. Use a minimum of 15 gal/A of water for ground applications. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy. Broccoli Brussels sprouts Cabbage Cauliflower See additional crops below. Use Rate fl oz product/A (lb ai) Inspire Page 23 Crop Brassica Head and Stem Vegetable Crop group 5-16 [Not for use in California] 5-7 {0.08 - 0.114) Target Diseases Alternaria diseases {Alternaria spp.) Anthracnose {Colletotrlchum higginsianum) Cercospora leafspot (C. brassicicola) Powdery mildew {Erysiphe polygon!) Including all cultivars and/or hybrids of these Complete list of Brassica Head and Stem Vegetables Crop group 5-16 including: Broccoli; Brussels sprouts; cabbage; cabbage, Chinese, napa; cauliflower; cultivars, varieties, and hybrids of these commodities________________________________________________ Specific Use Restrictions:

1. DO NOT apply more than 28 fl oz/A/year of Inspire.
2. DO NOT apply more than 7 fl oz per application (0.114 lb ai of difenoconazole).
3. DO NOT make more than 4 applications per year at the maximum application rate.
4. Minimum Application Interval: 7 days
5. DO NOT apply more than 0.46 lb ai/A/year of difenoconazole.
6. DO NOT apply within 1 day of harvest (1-day PHI).

See additional crops below. Optional language if label has a rate range and a single interval: If disease pressure is high, use the highest rate. Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval. Remarks Begin applications prior to disease onset when conditions are conducive for disease. Apply Inspire on a 7- to 10-day schedule making no more than 2 sequential applications before alternating to another fungicide with a different mode of action. Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and highest rate. Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by either ground, chemigation, or aerial application. Use a minimum of 15 gal/A of water for ground applications. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy. Arugula Chinese cabbage Bok Choy Collards Kale Mustard greens Turnip greens Inspire Page 24 Crop Brassica Leafy Greens Subgroup 4- 16B [Not for use in California] Target Diseases Alternaria diseases {Alternaria spp.) Anthracnose {Colletothchum higginsianum) Cercospora leafspot {C. brassicicola) Powdery mildew {Erysiphe polygon!) Use Rate fl oz product/A (Ibai) 5-7 (0.08-0.114) See separate instructions for watercress. Complete list of Brassica Leafy Greens Vegetable subgroup 4-1 6B including: Arugula; broccoli raab; broccoli, Chinese; cabbage, abyssinian; cabbage, seakale; cabbage, Chinese, bok choy; collards; cress, garden; cress, upland; hanover salad; kale; maca, leaves; mizuna; mustard greens; radish, leaves; rape greens; rocket, wild; shepherd's purse; turnip greens; cultivars, varieties, and hybrids of these commodities____________________________________ Specific Use Restrictions:

1. DO NOT apply more than 28 fi oz/A/year of Inspire.
2. DO NOT apply more than 7 fl oz per application (0.114 lb ai of difenoconazole).
3. DO NOT make more than 4 applications per year at the maximum application rate.
4. Minimum Application Interval: 7 days
5. DO NOT apply more than 0.46 lb ai/A/year of difenoconazole.
6. DO NOT apply within 1 day of harvest (1-day PHI).

0.114) Optional language if label has a rate range and a single interval: If disease pressure is high, use the highest rate. Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval. Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and highest rate. Remarks Begin applications prior to disease onset when conditions are conducive for disease. Apply Inspire on a 7- to 10-day schedule making no more than 2 sequential applications before alternating to another fungicide with a different mode of action. Inspire Page 25 Crop Bulb Vegetables [Not for use in California] Green Onion Subgroup 3- 07B Onions, green Leek Welsh onion tops Bulb Onion Subgroup 3- 07A Onions, bulb Garlic Shallot Target Diseases Cercospora leafspot (0. duddiae) Leaf blotch (Cladosporium allii-cepae) Powdery Mildew (Leveillula taurica) Purple blotch (Alternaha porri) Stemphyllium leaf blight (S. vesicarium) Cladosporium leaf blotch (C. allii) Rust (Puccinia allii) Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by either ground, chemigation, or aerial application. Use a minimum of 15 gal/A of water for ground applications. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy._______________________________________ Bulb onion subgroup 3-07A: Daylily, bulb; fritillaria, bulb; garlic, bulb; garlic, great-headed, bulb; garlic, serpent, bulb; lily, bulb; onion, bulb; onion, Chinese, bulb; onion, pearl; onion, potato, bulb; shallot, bulb; cultivars, varieties, and/or hybrids of these. Green onion subgroup 3-07B: Chive, fresh leaves; chive, Chinese, fresh leaves; elegans hosta; fritillaria, leaves; kurrat; lady’s leek; leek; leek, wild; onion, Beltsville bunching; onion, fresh; onion, green; onion, macrostem; onion, tree, tops; onion, Welsh, tops; shallot, fresh leaves; cultivars, varieties, and/or hybrids of these_______________________________________________________ Specific Use Restrictions:

1. For green onions, DO NOT apply more than 21 fl oz/A/year of Inspire.
2. For dry bulb onions, DO NOT apply more than 28 fl oz/A/year of Inspire.
3. DO NOT apply more than 7 fl oz per application (0.114 lb ai of difenoconazole).
4. For green onions, DO NOT make more than 3 applications per year at the maximum application rate.
5. For dry bulb onions, DO NOT make more than 4 applications per year at the maximum application rate.
6. Minimum Application Interval: 7 days
7. DO NOT apply more than 0.34 lb ai/A/year of difenoconazole to green onions.
8. DO NOT apply more than 0.46 lb ai/A/year of difenoconazole to dry bulb onions.
9. DO NOT apply within 7 days of harvest (7-day PHI). Use Rate fl oz product/A (lb ai) 5-7 (0.08 -

Powdery mildew {Erysiphe spp.) Optional language if label has a rate range and a single interval: If disease pressure is high, use the highest rate. Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval. Remarks Begin applications prior to disease onset when conditions are conducive for disease. Apply Inspire on a 7- to 10-day schedule making no more than 2 sequential applications before alternating to another fungicide with a different mode of action. Crop Carrots [Not for use in California] Inspire Page 26 Alternaria leaf blight {Alternaria dauci) Optional language if label has a rate range and interval range: If disease pressure is high, use I the shortest interval and highest rate.__ Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by either ground, chemigation, or aerial application. Use a minimum of 15 gal/A of water for ground applications. For aerial applications, use a minimum of 10 gal/A of water. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy.________________________________________________ Specific Use Restrictions:

1. DO NOT apply more than 28 fl oz/A/year of Inspire.
2. DO NOT apply more than 7 fl oz per application {0.114 lb ai of difenoconazole).
3. DO NOT make more than 4 applications per year at the maximum application rate.
4. Minimum Application Interval: 7 days
5. DO NOT apply more than 0.46 lb ai/A/year of difenoconazole.
6. DO NOT apply within 7 days of harvest {7-day PHI). Target Diseases Cercospora leaf spot {Cercospora carotae) Use Rate fl oz product/A (lb ai) 5.5-7 (0.09-0.114)

Powdery mildew {LeveiHula taurica) Remarks Begin applications prior to disease onset when conditions are conducive for disease. Make Inspire applications at least 14 days apart, making no more than 2 sequential applications before alternating to another fungicide with a different mode of action. Optional language if label has a rate range and a single interval: If disease pressure is high, use the highest rate. Ascochyta blight (A. rabiei) Inspire Page 27 Rust {Uromyces ciceris-ahetini) |____________________________________________________ Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by either ground, chemigation, or aerial application. Use a minimum of 15 gal/A of water for ground applications. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy.__________________________ Specific Use Restrictions:

1. DO NOT apply more than 28 fl oz/A/year of Inspire.
2. DO NOT apply more than 7 fl oz per application {0.114 lb ai of difenoconazole).
3. DO NOT make more than 4 applications per year at the maximum application rate.
4. Minimum Application Interval: 14 days
5. DO NOT apply more than 0.46 lb ai/A/year of difenoconazole.
6. DO NOT apply within 14 days of harvest (14-day PHI). Crop Chickpea [Not for use in California] Target Diseases Alternaria blight (A. alternate) Use Rate fl oz product/A (lb ai) 5.5-7 (0.09-0.114)

Including all cultivars and/or hybrids of these See additional crops in this subgroup below. Optional language if label has a rate range and a single interval: If disease pressure is high, use the highest rate. Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval. Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and highest rate. Remarks Begin Inspire applications prior to disease development and continue throughout the season on 7- to 21-day intervals following the resistance management guidelines. Applications may be made by ground or air. An adjuvant may be added at directed rates. Use a horticultural spray oil to improve control of greasy spot. Grapefruit Lemon Lime Orange (sour and sweet) Tangerine Use Rate fl oz product/A (lb ai) Inspire Page 28 5-7.7 (0.08 - 0.125) Target Diseases Greasy spot (Mycosphaerella citri) Melanose (Diaporthe citri) Scab (Elsinoe fawcettii) Sweet orange scab (Elsinoe australis) Albinism (Altemaria alternate pv citri) Post bloom fruit drop (PFD) (Colletotrichum acutatum) Altemaria leaf and fruit spot (Altemaria citri) Diplodia stem-end rot {Diplodia natalensis) Phomopsis stem­ end rot {Phomopsis citrii) Anthracnose {Colletotrichum spp.) Black spot {Guignardia citricarpa)______ Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by either ground or aerial application. Use a minimum of 15 gal/A of water for ground applications. For aerial applications, use a minimum of 10 gal/A of water._____________________________________________ Citrus Fruit subgroup: Australian desert lime; Australian finger-lime; Australian round lime; Brown River finger lime; calamondin; citrus citron; citrus hybrids (includes chironja, tangelo, tangor); grapefruit; Japanese summer grapefruit; kumquat; lemon; lime; Mediterranean mandarin; mount white lime; New Guinea wild lime; mandarin (tangerine); orange, sour; orange, sweet; pummelo; Russell River lime; satsuma mandarin; sweet lime; tachibana orange; Tahiti lime; tangelo; tangor; trifoliate orange; uniq fruit; cultivars, varieties, and/or hybrids of these____________________________________________ Specific Use Restrictions:

1. DO NOT apply more than 28.3 fl oz/A/year of Inspire.
2. DO NOT apply more than 7.7 fl oz per application (0.125 lb ai of difenoconazole).
3. DO NOT make more than 3 applications per year at the maximum application rate.
4. Minimum Application Interval: 7 days
5. DO NOT apply more than 0.5 lb ai/A/year of difenoconazole.
6. Inspire may be applied up to the day of harvest (0-day PHI). Crop Citrus Fruit Crop Group 10-10 [Not for use in California]

Areolate mildew {Ramulaha gossypii) Target spot {Corynespora cassiicola} Leafspots and blights {Alternaria spp., Ascochyta gossypii, Cercospora spp., Stemphyllium spp.) For foliar disease control, the first application must be targeted approximately at pin-head square to first bloom or when conditions are conducive for disease development. For best control of target spot, adjust the GPA to ensure coverage of upper and lower leaves. Subsequent applications may be made on a 14-21 day interval. Do not apply more than two sequential applications before alternating to a I fungicide with a different mode of action. Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by ground, chemigation, or aerial application. For aerial applications, use a minimum of 5 gal/A of water. Applicators must use care in making applications near non-target aquatic habitats.________________________________________________ Specific Use Restrictions:

1. DO NOT apply more than 21 fl oz/A/year of Inspire.
2. DO NOT apply more than 7 fl oz per application {0.114 lb ai of difenoconazole).
3. DO NOT make more than 3 applications per year at the maximum application rate.
4. Minimum Application Interval: 14 days
5. DO NOT apply more than 0.34 lb ai/A/year of difenoconazole.
6. DO NOT apply Inspire within 45 days of harvest (45-day PHI). Use Rate fl oz product/A (lb ai) Remarks For best activity, apply Inspire prior to or early in the disease development. An adjuvant may be added at specified rates. Inspire Page 29 Target Diseases Alternaria leafspot {Aiternaha spp.) 5.0 - 7.0 (0.08 - 0.114) _______Crop Cotton (Subgroup 20C) [Not for use in California]

Do not apply more than two sequential applications before alternating to a fungicide with a different mode of action. Remarks For best activity, apply Inspire prior to or early in the disease development. An adjuvant may be added at specified rates. Apply on a 7-14 day interval. Use Rate fl oz product/A (lb ai) 7 (0.114) Inspire Page 30 Target Diseases Bitter rot {Colletotrichum gloeosporioides) Blotch rot {Physalospora vaccinia) Cottonball (Monilinia oxycocci) Leaf rust (Pucciniastrum vaccinii) Ripe rot {Coleophoma empetri)_________ Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by ground, chemigation, or aerial application. For aerial applications, use a minimum of 5 gal/A of water. Applicators must use care in making applications near non-target aquatic habitats.___________________________________________________________________________ Specific Use Restrictions:

1. DO NOT apply more than 21 fl oz/A/year of Inspire.
2. DO NOT apply more than 0.34 lb ai/A/year of difenoconazole.
3. DO NOT apply more than 7 fl oz per application (0.114 lb ai of difenoconazole).
4. DO NOT make more than 3 applications per year.
5. Minimum Application Interval: 7 days
6. DO NOT allow release of irrigation or flood water for at least 7 days after the last application.
7. DO NOT apply when weather conditions favor drift from treated areas to non-target aquatic habitat.
8. DO NOT treat fields used for aquaculture of fish or crustacean.
9. DO NOT drain water from treated fields into ponds used for aquaculture of fish or crustacean.
10. DO NOT use water drained from treated field to irrigate other crops.
11. DO NOT apply Inspire within 30 days of harvest (30-day PHI). _______Crop Cranberry [Not for use in California]

0.114) 0.13-0.16 Cantaloupe Cucumber Honeydew Muskmelon Watermelon Pumpkin Squash Zucchini Including cultivars and/or hybrids of these See additional cucurbit crops below. Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval. Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and highest rate. Optional language if label has a rate range and a single interval: If disease pressure is high, use the highest rate. Greenhouse Use for Cucumber only: For production in covered areas, use Inspire for no more than 50% of sprays per crop. Rotate with other registered products with different modes of action (FRAC codes). 5-7 (0.08 - Remarks Begin applications prior to disease onset when conditions are conducive for disease. Apply Inspire on a 7- to 10-day schedule making no more than 2 sequential applications before alternating to another fungicide with a different mode of action. Use Rate fl oz product/A (lb ai) Inspire Page 31 Septoria leaf blight (S. cucurbitacearum) Plectosporium blight (P. tabacinum) Phoma blight (P. exigua) Phyllosticta leafspot (P- cucurbitacearum) Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by either ground, chemigation, or aerial application. Use a minimum of 15 gal/A of water for ground applications (20 for gummy stem blight). For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy.___________ Complete list of cucurbit crops: Chayote (fruit); Chinese waxgourd (Chinese preserving melon); citron melon; cucumber; gherkin; gourd, edible (includes hyotan, cucuzza, hechima, Chinese okra); Momordica spp. (includes balsam apple, balsam pear, bittermelon, Chinese cucumber); muskmelon (includes cantaloupe); pumpkin; squash, summer; squash, winter (includes butternut squash, calabaza, hubbard squash, acorn squash, spaghetti squash); watermelon________________________________ Specific Use Restrictions:

1. Greenhouse use is only for cucumber. o DO NOT apply more than 28 fl ozlf\l/ear of Inspire for greenhouse use. o DO NOT apply more than 0.46 lb ai/A/year of difenoconazole.
2. Field Use: o DO NOT apply more than 28 fl oz/A/year of Inspire. o DO NOT apply more than 0.46 lb ai/A/year of difenoconazole.
3. DO NOT apply more than 7 fl oz per application (0.114 lb ai of difenoconazole).
4. DO NOT make more than 4 applications per year at the maximum application rate.
5. Minimum Application Interval: 7 days
6. Inspire may be applied up to the day of harvest (0-day PHI). floz/1000 sq fl Crop Cucurbit Vegetables Crop Group 9 [Not for use in California] Target Diseases Powdery mildew {Sphaerotheca fuliginea, Erysiphe cichoracearum) Alternaria leaf blight (A. cucumerina) Alternaria leaf spot (A. altemata) Anthracnose {Colletotrichum orbiculare) Cercospora leafspot (C. citrullina) Gummy stem blight {Didymella bryoniae)

0.114) Optional language if label has a rate range and a single interval'. If disease pressure is high, use the highest rate. Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval. 5-7 (0.08 - Remarks Begin applications prior to disease onset when conditions are conducive for disease. Apply Inspire on a 14- to 21-day schedule making no more than 2 sequential applications before alternating to another fungicide with a different mode of action. Use Rate fl oz product/A (lb ai) Inspire Page 32 Optional language if label has a rate range and interval range'. If disease pressure is high, use I the shortest interval and highest rate.__ Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by either ground or aerial application. Use a minimum of 15 gal/A of water for ground applications. For aerial applications, use a minimum of 10 gal/A of water._________________________ Specific Use Restrictions:

1. DO NOT apply more than 28 fi oz/A/year of Inspire.
2. DO NOT apply more than 0.46 lb ai/A/year of difenoconazole.
3. DO NOT apply more than 7 fl oz per application (0.114 lb ai of difenoconazole).
4. DO NOT make more than 4 applications per year at the maximum application rate.
5. Minimum Application Interval: 14 days
6. DO NOT apply within 14 days of harvest (14-day PHI). Crop Filberts (Hazelnuts) [Not for use in California] Target Diseases Eastern Filbert Blight {Anisogramma anomala)

See additional crops in this subgroup below. Optional language if label has a rate range and a single interval'. If disease pressure is high, use the highest rate. Eggplant Groundcherry Pepino Pepper (includes bell pepper, chili pepper, cooking pepper, pimento, sweet pepper) Tomatillo Tomato Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval. Optional language if label has a rate range and interval range'. If disease pressure is high, use the shortest interval and highest rate. Remarks Begin applications at first sign of disease or when conditions are conducive for disease development. Apply Inspire on a 7- to 14-day schedule. Inspire can be used in blocking program using a maximum of two consecutive applications before rotating to fungicides with another mode of action that are registered for these diseases. If disease pressure is high, use the highest rate and shortest interval. Inspire Page 33 Crop Fruiting Vegetables Crop Group 8- 10 [Not for use in California] Target Diseases Early blight {Alternaria solani) Black mold (A. alternate} Gray leafspot {Stemphylium botryosum} Powdery mildew {Leveillula taurica} Septoria leafspot (S. lycopersici) Target spot {Corynespora cassiicola} Anthracnose {Colletotrichum spp.) Leaf mold (Fulvia fulva) Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by either ground, chemigation, or aerial application. Use a minimum of 15 gal/A of water for ground applications. For aerial applications, use a minimum of 5 gal/A of water. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy.____________________________________________________________ Fruiting Vegetables subgroup: African eggplant; bush tomato; bell pepper; cocona; currant tomato; eggplant; garden huckleberry; goji berry; groundcherry; martynia; naranjilla; okra; pea eggplant; pepino; pepper, bell; pepper, nonbell; roselie; scarlet eggplant; sunberry; tomatillo; tomato; tree tomato; cultivars, varieties, and/or hybrids of these________________________________________________ Specific Use Restrictions:

1. DO NOT apply more than 28 fl oz/A/year of Inspire.
2. DO NOT apply more than 0.46 lb ai/A/year of difenoconazole.
3. DO NOT apply more than 7 fl oz per application (0.114 lb ai of difenoconazole).
4. DO NOT make more than 4 applications per year at the maximum application rate.
5. Minimum Application Interval: 7 days
6. Inspire may be applied up to the day of harvest (0-day PHI). Use Rate fl oz product/A (lb ai) 4-7 (0.065- 0.114)

Powdery mildew {Erysiphe spp.) Remarks Begin applications prior to disease onset when conditions are conducive for disease. Apply Inspire on a 7- to 14-day schedule making no more than 2 sequential applications before alternating to another fungicide with a different mode of action.___________________ Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by ground, chemigation, or aerial application. Use a minimum of 15 gal/A for ground applications. For aerial applications, use a minimum of 10 gal/A of water. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy. Specific Use Restrictions:

1. DO NOT apply more than 28 ft oz/A/year of Inspire.
2. DO NOT apply more than 0.46 lb ai/A/year of difenoconazole.
3. DO NOT apply more than 7 fl oz per application (0.114 lb ai of difenoconazole).
4. DO NOT make more than 4 applications per year.
5. Minimum Application Interval: 7 days
6. Inspire may be applied up to the day of harvest (O-day PHI). Use Rate fl oz product/A (lb ai) 7 (0.114) Inspire Page 34 _______Crop Ginseng [Not for use in California] Target Diseases Alternaria blight (A. panax)

Optional language if label has a rate range and a single interval'. If disease pressure is high, use the highest rate. Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval. Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and highest rate. For Black rot - begin when shoot length is 1-3 inches and continue on a 10-day interval making no more than 2 sequential applications before alternating to another fungicide with a different mode of action. For all other diseases, begin applications prior to disease onset when conditions are conducive for disease. Apply Inspire on a 10- to 21-day schedule making no more than 2 sequential applications before alternating to another fungicide with a different mode of action. Remarks For powdery mildew, begin at bud break and apply on a 10- to 21-day interval, making no more than 2 sequential applications before alternating to a fungicide with a different mode of action. PRECAUTION: On V. labrusca, V. labrusca hybrids and other non-viniferea hybrids where sensitivity is not known, the use of Inspire by itself or in tank mixtures with materials that may increase uptake (adjuvants, foliar fertilizers) may result in I leaf burning or other phytotoxic effects. Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by either ground or aerial application. Use a minimum of 15 gal/A of water for ground applications. For aerial applications, use a minimum of 10 qal/A of water._________________________ Complete list of small fruit vine climbing, except fuzzy kiwifruit, subgroup 13-07F: Amur river grape; gooseberry; grape; kiwifruit, hardy; maypop; schisandra berry; cultivars, varieties, and/or hybrids of these____________________________________________________________________________ Specific Use Restrictions:

1. DO NOT apply more than 28 fl oz/A/year of Inspire.
2. DO NOT apply more than 0.46 lb ai/A/year of difenoconazole.
3. DO NOT apply more than 7 fl oz per application {0.114 lb ai of difenoconazole).
4. DO NOT make more than 4 applications per year at the maximum application rate.
5. Minimum Application Interval: 10 days (Fruit, small, vine climbing, except fuzzy kiwifruit - subgroup 13-07F) [Not for use in California] Crop Grapes (except Concord, Concord Seedless, and Thomcord. See Precaution under Remarks) See additional crops in this subgroup below. Use Rate fl oz product/A (lb ai) Inspire Page 35 5-7 (0.08 - 0.114) Target Diseases Alternaria rot {A. alternate) Powdery mildew {Uncinula necator) Rotbrenner {Pseudopezicula tracheiphila) Septoria leaf spot {S. ampelina) Black Rot {Guignarda bidweliii) Angular leafspot {Mycosphearella angulata) Anthracnose {Elsinoe ampelina) Leaf Blight {Pseudocercospora vitis)

Crop Target Diseases Remarks Crop Guava [Not for use in California] Do not apply more than two sequential applications before alternating to a fungicide with a different mode of action. Remarks For best activity, apply Inspire prior to or early in the disease development. An adjuvant may be added at specified rates. Apply on a 7-14 day interval. Use Rate fl oz product/A (lb ai) 6) DO NOT apply within 7 days of harvest (7-dav PHI Use Rate fl oz product/A (lb ai) 7 (0.114) Inspire Page 36 Target Diseases Alternaria Fruit Rot {Alternaria spp.) Anthracnose {Colletotrichum gloeosporioides) Suppression Rust (Puccinia psidii) Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by ground, chemigation, or aerial application. For aerial applications, use a minimum of 10 gal/A of water. Applicators must use care in making applications near non-target aquatic habitats.____________________________________________________________________________ Specific Use Restrictions:

1. DO NOT apply more than 28 fl oz/A/year of Inspire.
2. DO NOT apply more than 0.46 lb ai/A/year of difenoconazole.
3. DO NOT apply more than 7 fl oz per application (0.114 lb ai of difenoconazole).
4. DO NOT make more than 4 applications per year.
5. Minimum Application Interval: 7 days
6. Inspire may be applied the day of harvest. (0-day PHI).

Optional language if label has a rate range and a single interval'. If disease pressure is high, use the highest rate. Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval. Remarks Begin applications prior to disease onset when conditions are conducive for disease. Apply Inspire on a 7- to 10-day schedule making no more than 2 sequential applications before alternating to another fungicide with a different mode of action. Inspire Page 37 Optional language if label has a rate range and interval range: If disease pressure is high, use I the shortest interval and highest rate. Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by either ground, chemigation, or aerial application. Use a minimum of 15 gal/A of water for ground applications. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy.____________________________ Specific Use Restrictions:

1. DO NOT apply more than 28 fi oz/A/year of Inspire.
2. DO NOT apply more than 0.46 lb ai/A/year of difenoconazole.
3. DO NOT apply more than 7 fl oz per application {0.114 lb ai of difenoconazole).
4. DO NOT make more than 4 applications per year at the maximum application rate.
5. Minimum Application Interval: 7 days
6. DO NOT apply within 1 day of harvest (l-day PHI). Crop Kohlrabi [Not for use in California] Target Diseases Alternaria diseases {Alternaria spp.) Anthracnose {Colletotrichum higginsianum) Cercospora leafspot (C. brassicicola) Powdery mildew (Erysiphe polygon!} Use Rate fl oz product/A (lb ai) 5-7 (0.08-0.114)

Do not apply more than two sequential applications before alternating to a fungicide with a different mode of action. Optional language if label has a rate range and a single interval: If disease pressure is high, use the highest rate. Remarks For best activity, apply Inspire prior to or early in the disease development. An adjuvant may be added at specified rates. Apply on a 7-14 day interval. Remarks Begin applications prior to disease onset when conditions are conducive for disease. Apply Inspire on a 14-day schedule making no more than 2 sequential applications before alternating to another fungicide with a different mode of action. Crop Pecans [Not for use in California] Target Diseases Pecan Scab (Cladosporium caryigenum) Downy Spot {Mycosphaerella caryigena) Liver Spot {Gnomonia caryae) Vein Spot {Gnomomia nerviseda) Zonate Leaf Spot {Grovesinia pyramidalis) Powdery Mildew {Microsphaera penicillata) Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by either ground or aerial application. Use a minimum of 15 gal/A of water for ground applications. For aerial applications, use a minimum of 10 gal/A of water.____________________________________________ Specific Use Restrictions:

1. DO NOT apply more than 28 fl oz/A/year of Inspire.
2. DO NOT apply more than 0.46 lb ai/A/year of difenoconazole. Use Rate fl oz product/A (lb ai> Use Rate fl oz product/A (lb ai) 7 (0.114) Inspire Page 38 Target Diseases Blossom blight and fruit rot {Colletotrichum gloeosporioides) Aiternaria fruit spot (A. alternate) Powdery Mildew {Erysiphe spp.) Brown Spot (Corynespora cassicola)_______ Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by ground, chemigation, or aerial application. For aerial applications, use a minimum of 10 gal/A of water. Applicators must use care in making applications near non-target aquatic habitats.____________________________________________________________________________ Specific Use Restrictions:
3. DO NOT apply more than 28 fl oz/A/year of Inspire.
4. DO NOT apply more than 0.46 lb ai/A/year of difenoconazole.
5. DO NOT apply more than 7 fl oz per application (0.114 lb ai of difenoconazole).
6. DO NOT make more than 4 applications per year.
7. Minimum Application Interval: 7 days
8. Inspire may be applied the day of harvest. (O-day PHI). 5-7 (0.08 - 0.114) _______Crop Papaya [Not for use in California]

Crop Target Diseases Remarks Use Rate fl oz product/A (Ibai) 3) DO NOT apply more than 7 fl oz per application (0.114 lb ai of difenoconazole). 4) DO NOT make more than 4 applications per year at the maximum application rate. 5) Minimum Application Interval: 14 days 6) DO NOT apply within 14 days of harvest (14-day PHI). Inspire Page 39

Inspire Page 40 Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval. For Botryosphaeria, begin applications when green leaf tissue becomes visible and continue on a 14- to 21-day interval. Make no more than 2 sequential applications before alternating to another fungicide with a different mode of action. Remarks Begin applications prior to disease onset when conditions are conducive for disease. Apply Inspire on a 14- to 21-day schedule making no more than 2 sequential applications before alternating to another fungicide with a different mode of action. Optional language if label has a rate range and a single interval: If disease pressure is high, use the highest rate. Use Rate fl oz product/A (lb ai) Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and highest rate. Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by either ground or aerial application. Use a minimum of 15 gal/A of water for ground applications. For aerial applications, use a minimum of 10 gal/A of water._________ Specific Use Restrictions:

1. DO NOT apply more than 28 fi oz/A/year of Inspire.
2. DO NOT apply more than 0.46 lb ai/A/year of difenoconazole.
3. DO NOT apply more than 7 fl oz per application {0.114 lb ai of difenoconazole).
4. DO NOT make more than 4 applications per year at the maximum application rate.
5. Minimum Application Interval: 14 days
6. DO NOT apply within 14 days of harvest (14-dav PHI). 5-7 (0.08 - 0.114) Crop Pistachios [Not for use in California] Target Diseases Panicle and Shoot Blight {Botryosphaeria dothidea) Alternaria late blight {Alternaria spp.) Septoria leaf spot (S. pistaciarum)

See additional crops in this subgroup below. Powdery Mildew; Begin applications of Inspire at tight cluster, and continue on a 7- to 10-day schedule. Follow Inspire with other fungicides as needed. Inspire Page 41 Apple Scab - Curative Spray Schedule: Use a forecasting system beginning at green tip. Apply within 48 hours of the onset of an infection period. Apply a follow-up spray within 7 days. For improved fruit scab control, combine Inspire with a protectant fungicide beginning at bloom. Cedar-Apple Rust, Quince Rust, and Brooks Fruit Spot: Begin applications preventively. Apply Inspire alone or in combination with a protectant fungicide on a 7- to 10-day schedule through the second cover­ spray. [Not for use in California] Remarks Apple Scab - Protective Spray Schedule: Apply every 7-10 days starting at %-% inch green tip or when environmental conditions become conducive for scab. Continue through petal fall until the threat of primary scab is complete. For improved fruit scab control, combine Inspire with a protectant fungicide beginning at bloom. Sooty Blotch, Flyspeck: For early season control, begin applications preventively. Apply Inspire alone or in combination with a protectant fungicide on a 7- to 10-day schedule through the second cover spray. ______________________________ Follow with other fungicides as needed._____ Resistance Management: To help prevent resistance, make no more than 2 consecutive applications with Inspire or another Group 3 fungicide or a Group 3 fungicide mixture before alternating to a different mode of action. Use Rate fl oz product/A (lb ai) 4 (0.065) Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by either ground or aerial application. Use a minimum of 40 gal/A of water for ground applications. For aerial applications, use a minimum of 10 gal/A of water.________________________________ Pome Fruit subgroup: Apple; azarole; crabapple; loquat; mayhaw; medlar; pear; pear, Asian; quince; quince, Chinese; quince, Japanese; tejocote; cultivars, varieties, and/or hybrids of these____________ Specific Use Restrictions:

1. DO NOT apply more than 20 fi oz/A/year of Inspire.
2. DO NOT apply more than 0.33 lb ai/A/year of difenoconazole.
3. DO NOT apply more than 4 fl oz per application (0.065 lb ai of difenoconazole).
4. DO NOT make more than 5 applications per year.
5. Minimum Application Interval: 7 days
6. DO NOT apply Inspire within 14 days of harvest (14-day PHI). Crop Pome Fruit Crop Group 11-10 Apple Crabapple Loquat Mayhaw Pear Pear, Oriental Quince Target Diseases Alternaria blotch {Alternaria spp.) Brooks fruit spot {Mycosphaereila pomi) Cedar apple rust {Gymnosprangium juniperi-virginianae} Flyspeck (Zygophiala jamacaicensis (Formerly known as Schizothyrium pomi) Powdery mildew (Podosphaera leucotricha) Quince rust {Gymonsporangium spp.) Scab {Venturia spp.) Sooty blotch (Gloeodes pomigena)

Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval. Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and highest rate. Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by either ground, chemigation, or aerial application. Use a minimum of 15 gal/A of water for ground applications. For aerial applications, use a minimum of 5 gal/A of water. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy.____________________________ Vegetables, tuberous and corm, subgroup: Arracacha, Arrowroot, Artichoke (Chinese and Jerusalem), Canna, Cassava (bitter and sweet). Chayote (root), Chufa, Dasheen (Taro), Ginger, Leren, Tanier, Tumeric, and Yam (bean and true) _______________________________________ Specific Use Restrictions:

1. DO NOT apply more than 28 fl oz/A/year of Inspire.
2. DO NOT apply more than 0.46 lb ai/A/year of difenoconazole.
3. DO NOT apply more than 7 fl oz per application (0.114 lb ai of difenoconazole).
4. DO NOT make more than 4 applications per year at the maximum application rate.
5. Minimum Application Interval: 7 days
6. DO NOT apply within 14 days of harvest (14-day PHI). Crop Potatoes Vegetable, Tuberous and corm subgroup 1C [Not for use in California] For other crops in this subgroup, please see below. Remarks_ Begin applications at first sign of disease or when conditions are conducive for disease development. Apply Inspire on a 7- to 14-day schedule. Inspire can be used in blocking program using a maximum of 2 consecutive applications before rotating to fungicides with another mode of action that are registered for these diseases. Optional language if label has a rate range and a single interval: If disease pressure is high, use the highest rate. Inspire Page 42 Target Diseases Black dot {Colletotrichum coccodes) Brown spot {Alternaria alternate) Early blight {Alternaria solani) Powdery mildew {Erysiphe cichoracearum) Septoria leafspot (Septoria spp.) Use Rate fl oz product/A (lb ai) 4-7 (0.065- 0.114)

For head rot, apply at 50% flowering. Including cultivars, varieties, and/or hybrids of these and others in this group (see below) DO NOT apply more than one application of Inspire per year. DO NOT apply more than 7 fl oz/A/year of Inspire. DO NOT apply more than 0.114 lb ai/A/year of difenoconazole. DO NOT apply more than 7 fl oz per application (0.114 lb ai of difenoconazole). DO NOT apply within 30 days of harvest (30-day PHI). If disease pressure is high, use the highest rate. Crop Rapeseed Subgroup 20A [Not for use in California] For Alternaria, make an application at the end of flowering/early pod set. For other foliar diseases, apply at first sign of disease. Inspire Page 43 Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by ground, air, or chemigation. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy._________________________ Complete List of Rapeseed Subgroup 20A: Borage, crambe, cuphea, echium, flax seed, gold of pleasure, hare’s ear mustard, lesquerella, lunaria, meadowfoam, milkweed, mustard seed, oil radish, poppy seed, rapeseed, sesame, sweet rocket and cultivars and/or hybrids of these________________ Specific Use Restrictions: 1) 2) 3) 4) Remarks For Phoma control, apply during the rosette stage between 2nd true leaf and bolting. Target Diseases Alternaria black spot (Alternaria brassicae) Black leg/Phoma (Leptosphaeria maculans) Cercospora leaf spot (C. brassicicola) Head rot (Rhizoctonia solani) Leaf spot and pod rot {Alternaria altemata) Powdery mildew {Erysiphe polygoni) Use Rate fl oz product/A (lb ai) 4-7 (0.065 - 0.114)

Inspire Page 44 Remarks Apply 7.5 fl oz when disease is less than 4 inches above water line usually between panicle differentiation (PD) +5 days to PD +10 days or at initial sign of disease. Under heavy disease pressure and conditions favorable for disease development, a second application may be applied. Crop Rice [Not for use in California] Use Rate fl oz product/A (lb ai) 7.5 (0.122) Suppression only; False smut {Ustilaginoidea virens) Kernel Smut {Neovossia barclayana) Stem Rot (Sclerotium oryzae) |________________________________ Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by ground or aerial application. For aerial applications, use a minimum of 5 gal/A of water. Applicators must use care in making applications near non-target aquatic habitats._________ Specific Use Restrictions:

1. DO NOT allow release of irrigation or flood water for at least 7 days after the last application.
2. DO NOT apply when weather conditions favor drift from treated areas to non-target aquatic habitat.
3. DO NOT apply more than 15 fl ozJNyear of Inspire.
4. DO NOT apply more than 0.244 lb ai/A/year of difenoconazole.
5. DO NOT apply more than 7.5 fl oz per application (0.122 lb ai of difenoconazole).
6. DO NOT make more than 2 applications per year.
7. Minimum Application Interval: 14 days
8. DO NOT apply Inspire within 28 days of harvest (28-day PHI).
9. DO NOT treat fields used for aquaculture of fish or crustacean.
10. DO NOT drain water from treated rice fields into ponds used for aquaculture of fish or crustacean.
11. DO NOT use water drained from treated field to irrigate other crops. Target Diseases Sheath Blight {Rhizoctonia solani) Aggregate Sheath Spot {Rhizoctonia oryzae- sativae) Black Sheath Rot {Gaeumannomyces graminis var. graminis) Sheath Spot {Rhizoctonia oryzae) Brown Leaf spot {Cochliobolus miyabeanus) Narrow Brown Leaf spot {Cercospora oryzae)

Optional language if label has a rate range and a single interval'. If disease pressure is high, use the highest rate. Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval. [Not for use in California] Remarks Apply Inspire on a 7- to 28-day schedule, alternating with a non-triazole fungicide (non- Group 3) that is registered for these diseases. See additional crops in this subgroup below. See specific Directions for Carrots and Ginseng. Inspire Page 45 Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and highest rate. Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by either ground, chemigation, or aerial application. Use a minimum of 15 gal/A of water for ground applications. For aerial applications, use a minimum of 5 gal/A of water. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy._______________________________________ Vegetables, Root Subgroup: Beet, garden; beet, sugar; burdock, edible; celeriac; chervil, turnip- rooted; chicory; horseradish; parsley, turnip-rooted; parsnip; radish; radish, oriental (daikon); rutabaga; salsify; salsify, black; salsify, Spanish; skirret; turnip________________________________________ Specific Use Restrictions:

1. DO NOT apply more than 28 fl ozJAJyear of Inspire.
2. DO NOT apply more than 0.46 Ib ai/A/year of difenoconazole.
3. DO NOT apply more than 7 fl oz per application (0.114 Ib ai of difenoconazole).
4. DO NOT make more than 4 applications per year at the maximum application rate.
5. Minimum Application Interval: 7 days
6. DO NOT apply within 7 days of harvest (7-day PHI). Crop Root Vegetables, Subgroup 1A Radish Sugar beet Target Diseases Alternaria leafspots and blight {Alternaria spp.) Beet rust {Uromyces betae} Cercospora leafspot {Cercospora spp.) Powdery mildew {Erysiphe spp.) Use Rate fl oz product/A (Ib ai) 4-7 (0.065-0.114)

See additional crops in this group below. [Not for use in California] Optional language if label has a rate range and a single interval: If disease pressure is high, use the highest rate. Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval. Remarks Apply Inspire on a 7- to 28-day schedule, alternating with a non-triazole fungicide (non- Group 3) that is registered for these diseases. ____ Crop Leaves of Root and Tuber Vegetables, Group 2 Turnip Sugar beet Inspire Page 46 Target Diseases Alternaria leafspots and blight {Alternaria spp.) Beet rust {Uromyces betae) Cercospora leafspot {Cercospora spp.) Powdery mildew {Erysiphe spp.) Use Rate fl oz product/A (lb ai) 4-7 (0.065-0.114) Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and highest rate.__ Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by either ground, chemigation, or aerial application. Use a minimum of 15 gal/A of water for ground applications. For aerial applications, use a minimum of 5 gal/A of water. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy.____________________________________________________________ Leaves of Root and Tuber Vegetables Group: Beet, garden; beet, sugar; burdock, edible; carrot; cassava, bitter and sweet; celeriac (celery root); chervil, turnip-rooted; chicory; dasheen (taro); parsnip; radish; radish, oriental (daikon); rutabaga; salsily, black; sweet potato; tanier (cocoyam); turnip; yam, true_______________________________________________________________________________ Specific Use Restrictions:

1. DO NOT apply more than 28 fl oz/A/year of Inspire.
2. DO NOT apply more than 0.46 lb ai/A/year of difenoconazole.
3. DO NOT apply more than 7 fl oz per application (0.114 lb ai of difenoconazole).
4. DO NOT make more than 4 applications per year at the maximum application rate.
5. Minimum Application Interval: 7 days
6. DO NOT apply within 7 days of harvest (7-day PHI).

Alternaria leaf spot {Altemaria spp.) Brown spot {Septaria glycines) Cercospora blight and leaf spot (C. kikuchii) Frogeye leaf spot {Cercospora sojina) Optional language if label has a rate range and a single interval'. If disease pressure is high, use the highest rate. Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval. Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and highest rate. Remarks Begin applications prior to disease onset when conditions are conducive for disease. Apply Inspire on a 7- to 10-day schedule making no more than 2 sequential applications before alternating to another fungicide with a different mode of action. Inspire Page 47 Pod and stem blight {Diaporthe phaseolorum) Powdery mildew {Microsphaera diffusa)________________________________________________________ Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by either ground, chemigation, or aerial application. For aerial applications, use a minimum of 2 gal/A of water. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy.__________________________ Specific Use Restrictions:

1. DO NOT apply more than 13.5 fl oz/A/year of Inspire.
2. DO NOT apply more than 0.22 lb ai/A/year of difenoconazole.
3. DO NOT apply more than 7 fl oz per application (0.114 lb ai of difenoconazole).
4. DO NOT make more than 1 application per year at the maximum application rate.
5. Minimum Application Interval: 7 days
6. DO NOT apply within 14 days of harvest (14-day PHI).
7. DO NOT feed soybean hay, forage and silage. Crop Soybean [Not for use in California] Target Diseases Anthracnose {Colletotrichum truncatum) Use Rate fl oz product/A (lb ai) 5.5-7 (0.09-0.114)

And cultivars and/or hybrids of these Alternaria spot and fruit rot {A. alternata) Leaf rust {Tranzschelia discolor) Powdery mildew {Sphaerotheca pannosa, Podosphaera clandestina) Optional language if label has a rate range and a single interval: If disease pressure is high, use the highest rate. Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval. Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and highest rate. For all other diseases, follow the Brown rot blossom blight schedule. Make additional applications on a 10- to 14-day interval from the end of petal fall to harvest. Remarks For Brown rot blossom blight, begin applications at early bloom and continue through petal fall. For Brown rot on fruit, apply as needed a maximum of two sprays during the preharvest period up to the day of harvest (minimum of a 7- day retreatment interval). If high inoculum and severe disease conditions persist, apply a registered non-Group 3 fungicide. Shot hole {Wilsonomyces carpophilus)_________________________________________________________ Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by either ground or aerial application. Stone fruit diseases are most effectively controlled by ground applications. Use a minimum of 15 gal/A of water for ground applications. For aerial applications, use a minimum of 10 gal/A of water.______________________________ Stone Fruit Crop Group: Apricot; apricot, Japanese; capulin; cherry, black; cherry, Nanking; dierry, sweet; cherry, tart; Jujube, Chinese; nectarine; peach; plum; plum, American; plum, beach; plum, Canada; plum, cherry; plum, Chickasaw; plum. Damson; plum, Japanese; plum, Klamath; plum, prune; plumcot; sloe; cultivars, varieties, and/or hybrids of these____________________________________ Specific Use Restrictions:

1. DO NOT apply more than 28 fl oz/A/year of Inspire.
2. DO NOT apply more than 0.46 lb ai/A/year of difenoconazole.
3. DO NOT apply more than 7 fl oz per application (0.114 lb ai of difenoconazole).
4. DO NOT make more than 4 applications per year at the maximum application rate.
5. Minimum Application Interval: 7 days
6. Inspire may be applied up to the day of harvest (0-day PHI). Apricots Cherries, Sweet Cherries, Tart Nectarines Peaches Plums Plumcot Prunes Anthracnose {Colletotrlchum spp.) Scab {Cladosporium carpophilum) Inspire Page 48 Crop Stone Fruit Crop Group 12-12 [Not for use in California] Target Diseases Brown rot blossom blight and fruit rot {Monilinia fructicola, M. laxa) Use Rate fl oz product/A (lb ai) 5.5-7 (0.09-0.114)

Beechnut Brazil Nut Butternut Cashew Chestnut Macadamia Walnut, Black Walnut, English Optional language if label has a rate range and a single interval: If disease pressure is high, use the highest rate. Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval. Remarks Begin applications prior to disease onset when conditions are conducive for disease. Apply Inspire on a 14- to 21-day schedule making no more than 2 sequential applications before alternating to another fungicide with a different mode of action. Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and highest rate. Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by either ground, or aerial application. Use a minimum of 15 gal/A of water for ground applications. For aerial applications, use a minimum of 10 gal/A of water._________________________ Tree Nuts Crop Group: African nut-tree; almond; beechnut; Brazil nut; Brazilian pine; bunya; bur oak; butternut; Cajou nut; candlenut; cashew; chestnut; chinquapin; coconut; coquito nut; dika nut; ginkgo; Guiana chestnut; hazelnut (filbert); heartnut; hickory nut; Japanese horse-chestnut; macadamia nut; mongongo nut; monkey-pot; monkey puzzle nut; Okari nut; Pachira nut; peach palm nut; pecan; pequi; Pili nut; pine nut; pistachio; Sapucaia nut; tropical almond; walnut, black; walnut, English; yellowhom; cultivars, varieties, and/or hybrids of these________________________________________________ Specific Use Restrictions:

1. DO NOT apply more than 28 fl oz/A/year of Inspire.
2. DO NOT apply more than 0.46 lb ai/A/year of difenoconazole.
3. DO NOT apply more than 7 fl oz per application (0.114 lb ai of difenoconazole).
4. DO NOT make more than 4 applications per year at the maximum application rate.
5. Minimum Application Interval: 14 days
6. DO NOT apply within 14 days of harvest (14-day PHI). See specific Directions for Almonds Filberts Pecans Pistachios Target Diseases Foliar Diseases Inspire Page 49 Crop Tree Nuts Crop Group 14-12 [Not for use in California] Use Rate fl oz product/A (lb ai) 5-7 (0.08-0.114)

Remarks For best activity, apply Inspire prior to or early in the disease development. An adjuvant may be added at specified rates. Apply on a 7-14 day interval. Do not apply more than two sequential applications before alternating to a I fungicide with a different mode of action. Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by ground, chemigation, or aerial application. For aerial applications, use a minimum of 5 gal/A of water. Applicators must use care in making applications near non-target aquatic habitats.________________________________________________ Specific Use Restrictions:

1. DO NOT apply directly to water and DO NOT allow water in a treated field for at least 24 hours.
2. DO NOT apply more than 28 fl ozINyear of Inspire.
3. DO NOT apply more than 0.46 lb ai/A/year of difenoconazole.
4. DO NOT apply more than 7 fl oz per application (0.114 lb ai of difenoconazole).
5. DO NOT make more than 4 applications per year.
6. Minimum Application Interval: 7 days
7. Production fields must be drained of water at least 24 hours prior to application and water must not be reapplied to the field for a minimum of 24 hours following the application.
8. DO NOT apply inspire within 30 days of harvest (30-day PHI). _______Crop Watercress [Not for use in California] Inspire Page 50 Target Diseases Cercospora leafspot {Cercospora spp.) Use Rate fl oz product/A (lb ai) 7.0 (0.114)

Remarks Apply 7.5 fl oz/A at both booting and heading. Inspire Page 51 Brown Spot (Bipolarisspp.) |________________________________ Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by ground or aerial application. For aerial applications, use a minimum of 5 gal/A of water. Applicators must use care in making applications near non-target aquatic habitats._________ Specific Use Restrictions:

1. DO NOT allow release of irrigation or flood water for at least 7 days after the last application.
2. DO NOT apply when weather conditions favor drift from treated areas to non-target aquatic habitat.
3. DO NOT apply more than 15 fl oz/A/year of Inspire.
4. DO NOT apply more than 0.244 lb ai/A/year of difenoconazole.
5. DO NOT apply more than 7.5 fl oz per application {0.122 lb ai of difenoconazole).
6. DO NOT make more than 2 applications per year.
7. Minimum Application Interval: 14 days
8. DO NOT apply Inspire within 28 days of harvest (28-day PHI).
9. DO NOT use water drained from treated field to irrigate other crops.
10. DO NOT treat fields used for aquaculture of fish or crustacean.
11. DO NOT drain water from treated rice fields into ponds used for aquaculture of fish or crustacean.
12. DO NOT use water drained from treated field to irrigate other crops. Crop Wild Rice [Not for use in California] Target Diseases Helminthosporium leaf blight Use Rate fl oz product/A (lb ai) 7.5 (0.122)

Inspire Conversion Table Use the calibrated measuring [device] [syringe] supplied with the product to accurately measure the designated amount of product to be added to each gallon of water. Note: This use for application to ornamentals does not include crops grown for production, harvest and sale in commercial greenhouse or nursery production sites. Fl oz product/A 2_______ 3 ______ 4 ______ 5 ______ 5.5 6 ______ 7 ______ 7.5 7.7 8 ______ 15 _______ 20_______ 21 _______ 28_______ 28.3 Ornamentals - For outdoor application to established ornamentals in landscaped areas, to include recreational parks, institutional sites, golf courses and residential properties by commercial and non-professional (e.g., homeowner) applicators. Inspire Page 52 Lb ai/A 0.0325 0.05 0.065 0.08 0.09 0.10 0.114 0.122 0.125 0.13 0.244 0.325 0.341 0.456 0.460

Rust 4.8 7-14 Rust 1.4-2.7 7-21 4.8 7-14 STORAGE AND DISPOSAL DO NOT contaminate water, food, or feed by storage or disposal. Pesticide Storage Store in the original container in a cool place. Pesticide Disposal Pesticide wastes may be toxic. Improper disposal of excess pesticide, spray mixture, or rinsate is a violation of Federal Law. If these wastes cannot be disposed of by use according to label instructions, contact your State Pesticide or Environmental Control Agency, or the Hazardous Waste Representative of the nearest EPA Regional Office for guidance. Gladiolus [Not for use in California] Ornamental Carnation [Not for use in California] Disease Rust Timing of application Begin applications when flowers are half opened or when conditions are conducive for disease development. Apply Inspire on a 7- to 10-day schedule. Take particular care to achieve thorough coverage._______________________ Begin applications at the 2- to 3-leaf stage or when conditions are conducive for disease development. Apply Inspire on a 7- to 10-day schedule. Take particular care to achieve thorough coverage._______________________ Begin applications at the first sign of disease or when conditions are conducive for disease development. Apply Inspire on a 7- to 10-day schedule. Take particular care to achieve thorough coverage._______________________ Begin applications at the first sign of disease or when conditions are conducive for disease development. Apply Inspire on a 7- to 10-day schedule. Tale particular care to achieve thorough coverage. Restrictions: • For ornamentals, DO NOT apply more than 4.8 ml/1000 sq ft of Inspire (0.115 Ib ai/A) in a single application. • For ornamentals, DO NOT apply more than 19.2 ml/1000 sq ft of Inspire (0.46 Ib ai/A) per year. • DO NOT make more than 4 applications at the maximum application rate. • Minimum Application Interval: 7 days Iris [Not for use in California] Roses [Not for use in California] Black spot Rust Powdery mildew Spray interval days 7-10 Inspire Page 53 Rate MI/1 Gal (1 Gal Treats 1000 Sq Ft) 4.8

Container Handling [less than or equal to 5 gallons] Container Handling [greater than 5 gallons] J Container Handling [greater than 5 gallons] CONTAINER IS NOT SAFE FOR FOOD, FEED, OR DRINKING WATER. Inspire® and the SYNGENTA Logo are Trademarks of a Syngenta Group Company Viton® trademark of E. I. du Pont de Nemours and Company ©20XX Syngenta Refillable container. Refill this container with pesticide only. Do not reuse this container for any other purpose. Cleaning the container before final disposal is the responsibility of the person disposing of the container. Cleaning before refilling is the responsibility of the person refilling. To clean container before final disposal, empty the remaining contents from this container into application equipment or mix tank. Fill the container about 10 percent full with water. Agitate vigorously or recirculate water with the pump for 2 minutes. Pour or pump rinsate into application equipment or rinsate collection system. Repeat this rinsing procedure two more times. Then offer for recycling if available or puncture and dispose of in a sanitary landfill, or by incineration, or by other procedures approved by state and local authorities. Non-refillable container. Do not reuse or refill this container. Triple rinse container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank. Fill the container % full with water. Replace and tighten closures. Tip container on its side and roll it back and forth ensuring at least one complete revolution, for 30 seconds. Stand the container on its end and tip it back and forth several times. Turn the container over onto its other end and tip it back and forth several times. Empty the rinsate into application equipment or a mix tank or store rinsate for later use or disposal. Repeat this procedure two more times. Then offer for recycling if available or puncture and dispose of in a sanitary landfill, or by incineration, or by other procedures approved by state and local authorities. Non-refillable container. Do not reuse or refill this container. Triple rinse container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank and drain for 10 seconds after the flow begins to drip. Fill the container % full with water and recap. Shake for 10 seconds. Pour rinsate into application equipment or a mix tank or store rinsate for later use or disposal. Drain for 10 seconds after the flow begins to drip. Repeat this procedure two more times. Then offer for recycling if available or puncture and dispose of in a sanitary landfill, or by incineration, or by other procedures approved by state and local authorities. Inspire Page 54

INSPIRE 1262 MAS 0218 AMEND-G 0718-CL - sv 3/5/2020 000100-01262.20180726G.INSPIRE_AMEND_0718-CL.pdf For non-emergency (e.g. current product information) call Syngenta Crop Protection at 1-800-334-9481. Manufactured for: Syngenta Crop Protection. LLC P.O. Box 18300 Greensboro. North Carolina 27419-8300 Inspire Page 55

SUPPLEMENTAL LABELING DIFENOCONAZOLE | GROUP FUNGICIDE Inspire® Fungicide ACCEPTED Mar 20, 2020 KEEP OUT OF REACH OF CHILDREN. WARNING/AVISO EPA Reg. No. 100-1262 Syngenta 3 See additional precautionary statements and directions for use inside booklet. See First Aid statement inside booklet or on container label. Si usted no entiende la etiqueta, busque a alguien para que se la explique a usted en detalle. (If you do not understand the label, find someone to explain it to you in detail.) This supplemental label expires on 3/12/2023 and must not be used or distributed after this date. All applicable directions, restrictions and precautions on the EPA registered label are to be followed. Before using Inspire as permitted according to this supplemental label, read and follow all applicable directions, restrictions, and precautions on the EPA registered label on or attached to the pesticide product container. This Supplemental Labeling contains revised use instructions and or restrictions that may be different from those that appear on the container label. This Supplemental Labeling must be in the possession of the user at the time of pesticide application. It is a violation of Federal law to use this product in a manner inconsistent with its labeling. CAS No. 119446-68-3 Contains petroleum distillates Inspire is formulated as an emulsifiable concentrate (EC) containing 2.08 lb ai/gal of difenoconazole. Syngenta Crop Protection, LLC P. O. Box 18300 Greensboro. North Carolina 27419-8300 SCP ■ 23.2% 76.8% 100.0% Active Ingredient: Difenoconazole:.... Other Ingredients: Total: Un<ser Uie insecfiCKie. Fyiigicide and RodeiilfCide Ad as amencted. (or tiiB pealicide registered under NO 100.1262

DIRECTIONS FOR USE Optional language if label has a rate range and a single interval'. If disease pressure is high, use the highest rate. Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval. Remarks Apply Inspire on a 7- to 28-day schedule, alternating with a non-triazole fungicide (non- Group 3) that is registered for these diseases. See additional crops in this subgroup below. See specific Directions for Carrots and Ginseng. Inspire Page 2 Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and highest rate. Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by either ground, chemigation, or aerial application. Use a minimum of 15 gal/A of water for ground applications. For aerial applications, use a minimum of 5 gal/A of water. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy.______________________________________ Vegetables, Root Subgroup: Beet, garden; beet, sugar; burdock, edible; celeriac; chervil, turnip- rooted; chicory; horseradish; parsley, turnip-rooted; parsnip; radish; radish, oriental (daikon); rutabaga; salsify; salsify, black; salsify, Spanish; skirret; turnip________________________________________ Specific Use Restrictions:

1. DO NOT apply more than 28 fl oz/A/year of Inspire.
2. DO NOT apply more than 0.46 lb ai/A/year of difenoconazole.
3. DO NOT apply more than 7 fl oz per application (0.114 lb ai of difenoconazole).
4. DO NOT make more than 4 applications per year at the maximum application rate.
5. Minimum Application Interval: 7 days
6. DO NOT apply within 7 days of harvest (7-day PHI). Crop Root Vegetables, Subgroup 1A Radish Sugar beet [Not for use in California] Target Diseases Alternaria leafspots and blight {Alternaria spp.) Beet rust (Uromyces betae) Cercospora leafspot {Cercospora spp.) Powdery mildew {Erysiphe spp.) Use Rate fl oz product/A (lb ai) 4-7 (0.065-0.114)

©20XX Syngenta Inspire® and the Syngenta logo are trademarks of a Syngenta Group Company See additional crops in this group below. INSPIRE 1262 MAS 0218 TOLPET SUP-E JUN2018-CL - kdy - 3/12/20 000100-01262.20180726E.INSPIRE_AMEND-SUP_0718-CL.pdf Optional language if label has a rate range and a single interval: If disease pressure is high, use the highest rate. Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval. Remarks Apply Inspire on a 7- to 28-day schedule, alternating with a non-triazole fungicide (non- Group 3) that is registered for these diseases. Crop Leaves of Root and Tuber Vegetables, Group 2 Turnip Sugar beet [Not for use in California] Inspire Page 3 Target Diseases Alternaria leafspots and blight (Alternaria spp.) Beet rust (Uromyces betae) Cercospora leafspot (Cercospora spp.) Powdery mildew (Erysiphe spp.) Use Rate fl oz product/A (lb ai) 4-7 (0.065-0.114) Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and highest I rate.__________________ Application: For best results, sufficient water volume must be used to provide thorough coverage. Inspire can be applied by either ground, chemigation, or aerial application. Use a minimum of 15 gal/A of water for ground applications. For aerial applications, use a minimum of 5 gal/A of water. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy._____________________________________________ Leaves of Root and Tuber Vegetables Group: Beet, garden; beet, sugar; burdock, edible; carrot; cassava, bitter and sweet; celeriac (celery root); chervil, turnip-rooted; chicory; dasheen (taro); parsnip; radish; radish, oriental (daikon); rutabaga; salsily, black; sweet potato; tanier (cocoyam); turnip; yam, true_______________________________________________________________________________ Specific Use Restrictions:

1. DO NOT apply more than 28 fl oz/A/year of Inspire.
2. DO NOT apply more than 0.46 lb ai/A/year of difenoconazole.
3. DO NOT apply more than 7 fl oz per application (0.114 lb ai of difenoconazole).
4. DO NOT make more than 4 applications per year at the maximum application rate.
5. Minimum Application Interval: 7 days
6. DO NOT apply within 7 days of harvest (7-day PHI).