crop-chem-docs/corpus/epa_ppls/100-1389.md

AXIAL STAR HERBICIDE

• EPA Reg No: 100-1389
• Registrant: SYNGENTA CROP PROTECTION, LLC
• Signal word: Caution
• Active ingredients: Fluroxypyr 1-methylheptyl ester (12.4%); Pinoxaden (4.9%)
• Label accepted: 2026-03-03
• Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000100-01389-20260303.pdf

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March 3, 2026 Jordan Moseley Syngenta Crop Protection, LLC P.O. Box 18300 Greensboro, NC 27419 Subject: Label Amendment - Registration Review Mitigation for Pinoxaden and Fluroxypyr Product Name: Axial Star Herbicide EPA Registration Number: 100-1389 Application Dates: 12/16/2020 Decision Numbers: 473182; 677955 Dear Jordan Moseley: The Agency, in accordance with the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), as amended, has completed reviewing all the information submitted with your application to support the Registration Review of the above referenced product in connection with the Pinoxaden and Fluroxypyr Interim Decisions, and has concluded that your submission is acceptable. The label referred to above, submitted in connection with registration under FIFRA, as amended, is acceptable. Should you wish to add/retain a reference to the company’s website on your label, then please be aware that the website becomes labeling under the Federal Insecticide, Fungicide, and Rodenticide Act and is subject to review by the Agency. If the website is false or misleading, the product would be misbranded and unlawful to sell or distribute under FIFRA section 12(a)(1)(E). 40 CFR 156.10(a)(5) list examples of statements EPA may consider false or misleading. In addition, regardless of whether a website is referenced on your product’s label, claims made on the website may not substantially differ from those claims approved through the registration process. Therefore, should the Agency find or if it is brought to our attention that a website contains false or misleading statements or claims substantially differing from the EPA approved registration, the website will be referred to the EPA’s Office of Enforcement and Compliance Assurance. A stamped copy of your labeling is enclosed for your records. This labeling supersedes all previously accepted labeling and must be used at your next label printing. You must submit one copy of the final printed labeling before you release the product for shipment with the new labeling. In accordance with 40 CFR 152.130(c), you may

Page 2 of 2 EPA Reg. No. 100-1389 Decision No. 473182; 677955

distribute or sell this product under the previously approved labeling for 12 months from the date of this letter. After 12 months, you may only distribute or sell this product if it bears this new revised labeling or subsequently approved labeling. “To distribute or sell” is defined under FIFRA section 2(gg) and its implementing regulation at 40 CFR 152.3.

If you have any questions about this letter, please contact Jaclyn Pyne by email at pyne.jaclyn@epa.gov.

S i n c e r e l y ,

Jaclyn Pyne, Team Leader Risk Management and Implementation Branch 3 Pesticide Re-Evaluation Division Office of Pesticide Programs

ENCLOSURE: Stamped label

-1- PINOXADEN GROUP 1 HERBICIDE FLUROXYPYR GROUP 4 HERBICIDE Axial® Star Herbicide Postemergence herbicide for control of annual grass and broadleaf weeds in wheat and barley. Active Ingredient: Pinoxaden*: ............................................................................................................... 4.9% Fluroxypyr 1-methylheptyl ester**: ........................................................................... 12.4% Other Ingredients: 82.7% Total: 100.0% *CAS No. 243973-20-8 **CAS No. 81406-37-3 Contains 0.42 pounds of pinoxaden and 0.73 pounds of fluroxypyr acid equivalent per gallon. Contains petroleum distillates. KEEP OUT OF REACH OF CHILDREN. CAUTION See additional precautionary statements and directions for use inside booklet. EPA Reg. No. 100-1389 EPA Est. SCP 1389A ____ gallons Net Contents 03/03/2026 100-1389

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FIRST AID If on skin or clothing • Take off contaminated clothing. • Rinse skin immediately with plenty of water for 15-20 minutes. • Call a poison control center or doctor for treatment advice. If in eyes • Hold eye open and rinse slowly and gently with water for 15-20 minutes. • Remove contact lenses, if present after the first 5 minutes, then continue rinsing eye. • Call a poison control center or doctor for treatment advice. If swallowed • Immediately call a poison control center or doctor. • Do not induce vomiting unless told to do so by a poison control center or doctor. • Do not give any liquid to the person. • Do not give anything by mouth to an unconscious person. If inhaled • Move person to fresh air. • If person is not breathing, call 911 or an ambulance, then give artificial respiration, preferably by mouth-to-mouth, if possible. • Call a poison control center or doctor for further treatment advice. Have the product container or label with you when calling a poison control center or doctor or going for treatment. NOTE TO PHYSICIAN May pose an aspirational pneumonia hazard. Contains petroleum distillates. HOTLINE NUMBER For 24 Hour Medical Emergency Assistance (Human or Animal) or Chemical Emergency Assistance (Spill, Leak, Fire, or Accident) Call 1-800-888-8372

PRECAUTIONARY STATEMENTS

Hazards to Humans and Domestic Animals

CAUTION

Contains petroleum distillate. Avoid contact with skin or clothing. Causes moderate eye irritation. Wash thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco, or using the toilet. Wear long-sleeved shirt and long pants, socks, shoes, and gloves. Avoid contact with eyes or clothing. Wear protective eyewear. Prolonged or frequently repeated skin contact may cause allergic reactions in some individuals.

-3- Personal Protective Equipment (PPE)

Some materials that are chemical resistant to this product are listed below.

Applicators and other handlers must wear:

• Long-sleeved shirt and long pants • Shoes plus socks • Chemical-resistant gloves such as barrier laminate, butyl rubber ≥14 mils, nitrile rubber ≥14 mils, neoprene rubber ≥14 mils, polyvinyl chloride (PVC) ≥14 mils, or Viton® ≥14 mils • Protective eyewear

User Safety Requirements

Follow manufacturer’s instructions for cleaning/maintaining PPE. If no such instructions for washables exist, use detergent and hot water. Keep and wash PPE separately from other laundry.

Engineering Control Statements

When handlers use closed systems, enclosed cabs, or aircraft in a manner that meets the requirements listed in the Worker Protection Standard (WPS) for agricultural pesticides [40 CFR 170.240(d)(4-6)], the handler PPE requirements may be reduced or modified as specified in the WPS.

User Safety Recommendations

Users should:

• Wash hands before eating, drinking, chewing gum, using tobacco, or using the toilet. • Remove clothing/PPE immediately if pesticide gets inside. Then wash thoroughly and put on clean clothing. • Remove PPE immediately after handling this product. Wash the outside of gloves before removing. As soon as possible, wash thoroughly and change into clean clothing.

Environmental Hazards

This product is toxic to oysters. For terrestrial uses: Do not apply directly to water, to areas where surface water is present, or to intertidal areas below the mean high water mark. Do not contaminate water when disposing of equipment wash water or rinsate.

Non-Target Organism Advisory Statement

-4- This product is toxic to plants and may adversely impact the forage and habitat of non-target organisms, including pollinators, in areas adjacent to the treated site. Protect the forage and habitat of non-target organisms by following label directions intended to minimize spray drift.

Physical or Chemical Hazards

Do not use or store near heat or open flame.

CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY

NOTICE: Read the entire Directions for Use and Conditions of Sale and Limitation of Warranty and Liability before using this product. If the terms are not acceptable, return the product at once, unopened, and the purchase price will be refunded.

The Directions for Use of this product must be followed carefully. It is impossible to eliminate all risks inherently associated with the use of this product. Crop injury, ineffectiveness or other unintended consequences may result because of such factors as manner of use or application, weather or crop conditions, presence of other materials or other influencing factors in the use of the product, which are beyond the control of SYNGENTA CROP PROTECTION, LLC or Seller. To the extent permitted by applicable law, Buyer and User agree to hold SYNGENTA and Seller harmless for any claims relating to such factors.

SYNGENTA warrants that this product conforms to the chemical description on the label and is reasonably fit for the purposes stated in the Directions for Use, subject to the inherent risks referred to above, when used in accordance with directions under normal use conditions. To the extent permitted by applicable law: (1) this warranty does not extend to the use of the product contrary to label instructions or under conditions not reasonably foreseeable to or beyond the control of Seller or SYNGENTA, and, (2) Buyer and User assume the risk of any such use. TO THE EXTENT PERMITTED BY APPLICABLE LAW, SYNGENTA MAKES NO WARRANTIES OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE NOR ANY OTHER EXPRESS OR IMPLIED WARRANTY EXCEPT AS WARRANTED BY THIS LABEL.

To the extent permitted by applicable law, in no event shall SYNGENTA be liable for any incidental, consequential or special damages resulting from the use or handling of this product. TO THE EXTENT PERMITTED BY APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE USER OR BUYER, AND THE EXCLUSIVE LIABILITY OF SYNGENTA AND SELLER FOR ANY AND ALL CLAIMS, LOSSES, INJURIES OR DAMAGES (INCLUDING CLAIMS BASED ON BREACH OF WARRANTY, CONTRACT, NEGLIGENCE, TORT, STRICT LIABILITY OR OTHERWISE) RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, SHALL BE THE RETURN OF THE PURCHASE PRICE OF THE PRODUCT OR, AT THE ELECTION OF SYNGENTA OR SELLER, THE REPLACEMENT OF THE PRODUCT.

-5- SYNGENTA and Seller offer this product, and Buyer and User accept it, subject to the foregoing Conditions of Sale and Limitation of Warranty and Liability, which may not be modified except by written agreement signed by a duly authorized representative of SYNGENTA.

DIRECTIONS FOR USE

It is a violation of Federal law to use this product in a manner inconsistent with its labeling.

Axial Star Herbicide may be used only in accordance with directions on this label or in separately published Syngenta supplemental labeling directions for this product.

Do not apply this product in a way that will contact workers or other persons, either directly or through drift. Only protected handlers may be in the area during application. For any requirements specific to your State or Tribe, consult the State or Tribal agency responsible for pesticide regulation.

AGRICULTURAL USE REQUIREMENTS

Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR part 170. This Standard contains requirements for the protection of agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of agricultural pesticides. It contains requirements for training, decontamination, notification, and emergency assistance. It also contains specific instructions and exceptions pertaining to the statements on this label about personal protective equipment (PPE) and restricted-entry interval. The requirements in this box only apply to uses of this product that are covered by the Worker Protection Standard.

Do not enter or allow worker entry into treated areas during the restricted-entry interval (REI) of 48 hours.

PPE required for early entry to treated areas that is permitted under the Worker Protection Standard and that involves contact with anything that has been treated, such as plants, soil, or water is:

• Coveralls • Shoes plus socks • Chemical-resistant gloves such as barrier laminate, butyl rubber ≥14 mils, nitrile rubber ≥14 mils, neoprene rubber ≥14 mils, polyvinyl chloride (PVC) ≥14 mils, or Viton® ≥14 mils

FAILURE TO FOLLOW THE DIRECTIONS FOR USE AND PRECAUTIONS ON THIS LABEL MAY RESULT IN CROP INJURY AND/OR POOR WEED CONTROL.

-6- PRODUCT INFORMATION

Axial Star Herbicide is a postemergence systemic herbicide for the control of annual grasses and broadleaf weeds in all varieties of spring wheat (excluding durum), winter wheat, and barley not underseeded with legumes.

Axial Star Herbicide is absorbed by foliage and is rapidly translocated to the growing points of leaves and stems of target weeds with growth stopping within days of application. Susceptible grass weeds turn chlorotic (yellowing) within one to three weeks and are completely controlled within three to five weeks. Susceptible broadleaf weeds exhibit twisting and curling of stems (epinasty) and leaf cupping followed by growth inhibition and eventual plant death within weeks. Level and rate of control depend on weed species, growing conditions, crop competition, and coverage. Thorough spray coverage of target weeds is essential for consistent control.

Rainfastness

Axial Star Herbicide is not affected by rain falling 1 hour or more after application.

-7- Resistance Management PINOXADEN GROUP 1 HERBICIDE FLUROXYPYR GROUP 4 HERBICIDE

For resistance management, Axial Herbicide is a Group 1 herbicide (ACCase-inhibitor mode of action) and a Group 4 herbicide (auxin mimic). Some naturally occurring grass weed populations have been identified as resistant to herbicides with the ACCase-inhibitor mode of action. Any weed population may contain or develop plants naturally resistant to Axial Herbicide and other Group 1 and/or Group 4 herbicides. Selection of resistant biotypes, through repeated use of these herbicides in the same field or lower than labeled use rates, may result in weed control failures. The resistant biotypes may dominate the weed population if these herbicides are used repeatedly in the same field. Appropriate resistance management strategies should be followed. If resistance is suspected, contact your local Syngenta representative and/or agricultural advisor for assistance.

Principles of Herbicide Resistant Weed Management

Scout and know your field • Know weed species present in the field to be treated through scouting and field history. An understanding of weed biology is useful in designing a resistance management strategy. Ensure the weed management program will control all weeds present. • Fields should be scouted prior to application to determine species present and growth stage. Always apply this herbicide at the full labeled rate and correct timing for the weeds present in the field.

Utilize non-herbicidal practices to add diversity

• Use diversified management tactics including cover crops, mechanical weed control, harvest weed seed control, and crop rotation as appropriate.

Use good agronomic practices, start clean and stay clean • Use good agronomic practices that enhance crop competitiveness. • Plant into weed-free fields utilizing tillage or an effective burndown herbicide for control of emerged weeds. • Sanitize farm equipment to avoid spreading seed or vegetative propagules prior to leaving fields.

Difficult to control weeds

• Fields with difficult to control weeds should be planted in rotation with crops that allow the use of herbicides with an alternative mode of action or different management practices. • Difficult to control weeds may require sequential applications, for example a broad spectrum preemergence herbicide followed by one or more postemergence herbicide

-8- applications. Utilize herbicides containing different modes of action effective on the target weeds in sequential applications.

DO NOT overuse the technology

• DO NOT use more than two applications of this or any other herbicide with the same mode of action in a single growing season unless mixed with an herbicide with a different mode of action which provides overlapping spectrum for the difficult to control weeds.

Scout and inspect fields following application

• Prevent an influx of weeds into the field by controlling weeds in field borders. • Scout fields after application to verify that the treatment was effective. • Suspected- herbicide resistant weeds may be identified by these indicators • Failure to control a weed species normally controlled by the herbicide at the dose applied, especially if control is achieved on adjacent weeds; • A spreading patch of non-controlled plants of a particular weed species; and • Surviving plants mixed with controlled individuals of the same species. • Report non-performance of this product to your Syngenta retailer, Syngenta representative, or call 1-866-Syngent(a) (866-796-4368). If resistance is suspected ensure weed escapes are controlled using an herbicide with an effective mode of action and/or use non-chemical means to prevent further seed production.

Prevent weed escapes before, during, and after harvest

• DO NOT allow weed escapes to produce seed or vegetative structures for example tubers or stolons which contribute to spread and survival. Consider harvest weed seed management and control weeds post-harvest to prevent seed production.

Resistant weeds

Contact your local Syngenta representative, retailer, crop advisor or extension agent to determine if weeds resistant to the mode of action contained in this product are present in your area. Premixes are intended to broaden the spectrum of weeds that are controlled. Some weeds may be controlled by only one of the active ingredients in this product. If resistant biotypes have been reported, use the full labeled rate of this product, apply at the labeled timing, and tank-mix with an additional different mode of action product so there are multiple effective modes of application for each suspected resistant weed.

Rotational Crop Restrictions

The following crops may be planted at the specified interval following application of Axial Star Herbicide.

-9- Crop Rotation Interval (Months) Barley, wheat 0 All other crops 4

CROP USE DIRECTIONS

Wheat and Barley

Axial Star Herbicide can be used on all varieties of spring wheat (excluding durum), winter wheat, and barley.

Timing of Application

Apply Axial Star Herbicide to all varieties of spring wheat (excluding durum), winter wheat, and barley from the 2-leaf stage to pre-boot stage.

For optimum results, apply Axial Star Herbicide to actively growing weeds. An early application will maximize crop yields by reducing weed competition. Weed control following application of Axial Star Herbicide alone or in combination with other herbicides can be reduced or delayed under conditions of stress, such as drought, heat, insufficient fertility, flooding, and prolonged cool temperatures. Optimum weed control will be obtained if application of Axial Star Herbicide is delayed until the conditions of stress have ended and weeds are once again actively growing. Weeds emerging after Axial Star Herbicide application will not be controlled.

USE RATE

Apply Axial Star Herbicide at 16.4 fl. oz./A in a minimum of 8 gallons up to 10 gallons of water per acre.

USE RESTRICTIONS

• DO NOT apply to a crop that is stressed by conditions such as frost, low fertility, drought, flooding, disease damage, or insect damage as crop injury may result. • DO NOT allow spray to drift to adjacent fields seeded to crops other than wheat or barley. • DO NOT treat wheat or barley underseeded with legumes. • Make only one application per 12 consecutive months. • DO NOT graze livestock or harvest forage for hay from treated wheat and barley for a minimum of 30 days following application. • DO NOT harvest grain for 60 days following application. • DO NOT feed treated wheat or barley straw to livestock for a minimum of 60 days following application. • This product is persistent and may be presen t in plant materials for over 30 days after application. DO NOT use treated plant material for compost, mulch, or mushroom spawn until 30 days after application.

-10- • Animals that have been fed fluroxypyr-treated forage must be fed forage free of fluroxypyr for at least 3 days before they are moved off the treated property.

WEEDS CONTROLLED

Weeds Controlled by Axial Star Herbicide at 16.4 fl. oz/A.

Grass Weeds Controlled Weed Size or Growth Stage for Optimum Control Barnyardgrass (Echinochloa crus-galli) 1 to 5-leaf on the main stem, prior to emergence of the 3rd tiller Canarygrass (Phalaris spp.) 1 to 5-leaf on the main stem, prior to emergence of the 3rd tiller Darnel, Persian (Lolium persicum) 1 to 6-leaf on the main stem, prior to emergence of the 4th tiller Foxtail, Giant (Setaria faberi) 1 to 5-leaf on the main stem, prior to emergence of the 3rd tiller Foxtail, Green (Setaria viridis) 1 to 5-leaf on the main stem, prior to emergence of the 3rd tiller Foxtail, Yellow (Setaria pumila) 1 to 5-leaf on the main stem, prior to emergence of the 3rd tiller Oat, Volunteer (Avena sativa) 1 to 6-leaf on the main stem, prior to emergence of the 4th tiller Oat, Wild (Avena fatua) 1 to 6-leaf on the main stem, prior to emergence of the 4th tiller Proso Millet, Wild (Panicum miliaceum) 1 to 5-leaf on the main stem, prior to emergence of the 3rd tiller Ryegrass, Italian (Annual) (Lolium multiflorum) 1 to 5-leaf on the main stem, prior to emergence of the 3rd tiller Windgrass (Apera spp.) 1 to 5-leaf on the main stem, prior to emergence of the 3rd tiller

Broadleaf Weeds Controlled Weed Size or Growth Stage for Optimum Control Bedstraw, Catchweed (Galium aparine) Less than 4 inches tall Cocklebur, Common (Xanthium strumarium) Less than 4 inches tall Flax, Volunteer (Linum usitatissimum) Less than 4 inches tall Kochia (Kochia scoparia) Less than 4 inches tall Lettuce, Prickly (Lactuca serriola) 1 to 4-leaf sta ge Ragweed, Common (Ambrosia artemisiifolia) Less than 4 inches tall Sunflower, Common (Helianthus annuus) 1 to 4-leaf sta ge

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BROADLEAF HERBICIDE TANK-MIX RECOMMENDATIONS

Axial Star Herbicide may be tank mixed with the broadleaf herbicides listed below to broaden the weed control spectrum. Refer to the label of the tank-mix partner for registered crops, additional weeds controlled, and directions for use. Observe all precautions and restrictions on the labels of products used in tank mixtures. Use in accordance with the most restrictive of label limitations and precautions. This product cannot be mixed with any other product whose label prohibits such a mixture.

Under less than favorable environmental conditions, grass antagonism (i.e., reduced grass control) may occur with certain broadleaf herbicide tank mixes.

Precaution: The many formulations of tank-mix partners have varying mixing characteristics. Before Axial Star Herbicide is used in tank mixture with other products, the mixture should first be tested in small containers for physical compatibility. For directions on how to conduct a compatibility test, refer to the Tank-Mix Compatibility Test section.

Broadleaf Herbicide Tank-Mix Partners

Table 1: For control of wild oat, volunteer oat, green foxtail, yellow foxtail, Italian (annual) ryegrass, and additional broadleaf weeds (refer to the broadleaf tank-mix partner label for weeds controlled), use Axial Star Herbicide at 16.4 fl. oz./A plus one of the following single or two-way broadleaf herbicide combinations. Broadleaf herbicide combinations other than those listed in the table below are not recommended.

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SELECT ONLY ONE BROADLEAF HERBICIDE TANK-MIX COMBINATION LISTED IN THE TABLE BELOW

Grass Weeds Controlled by Axial Star Herbicide at 16.4 fl. oz./A in Combination With Listed Mixture Partners* Broadleaf HerbicideA Rate Wild Oat Volunteer Oat Green Foxtail Yellow Foxtail Italian Ryegrass Affinity® BroadSpecB 0.4 oz./A C C S C C Affinity® TankMixB 0.6 oz./A C C S C C Ally® XPB 0.1 oz./A C C - - C Amber®B 0.28-0.47 oz./A C C - - C AmberB + MCPA esterC 0.28-0.47 oz./A + 0.5-0.75 pt./A C C - - C Bronate Advanced™ 0.6-0.8 pt./A C C C C C Buctril® 0.75-1.25 pt./A C C C C C Curtail® M 1.75 pt./A C C C - - Express® XPB 0.25-0.33 oz./A C C S S C Finesse®B 0.2-0.4 oz./A C C - - C Harmony® Extra XPB 0.3-0.6 oz./A C C C C C Harmony® SGB 0.45-0.9 oz./A C C C C C Huskie™B 11 fl. oz./A C C C C C MCPA EsterC 0.5-0.75 pt./A C C C C C Orion®B 17 fl. oz./A C C C C C Peak®B 0.25-0.5 oz./A C C - - C PeakB + MCPA EsterC 0.25-0.5 oz./A + 0.5-0.75 pt./A C C - - C Pulsar™ 8.3 fl. oz./A C C C C C Pulsar + MCPA esterC 8.3 fl. oz./A + 8.6 fl. oz/A C C C C C

*C = Control; S = Suppression (indicates “Partial Control” which means significant activity but not always at a level generally considered acceptable for commercial weed control). AOther products that contain equivalent active ingredient(s) and used at the same active ingredient rate(s) as the broadleaf herbicide tank-mix partner listed in this table may be used. BAddition of surfactants is not required. CAssume 3.7 lb. ae/gal. product.

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TANK MIXES WITH FUNGICIDES, INSECTICIDES AND LIQUID NITROGEN FERTILIZER

Tank-Mix Application with Tilt® Fungicide

Axial Star Herbicide may be tank mixed with Tilt Fungicide for annual grass and broadleaf weed control and early season disease suppression. Apply Axial Star Herbicide at 16.4 fl. oz./A in a tank mix with Tilt Fungicide at labeled use rates. Refer to the Tilt Fungicide label for specific use directions, application rates, restrictions, and a list of diseases suppressed and/or controlled.

Tank-Mix Application with Quilt® Fungicide

Axial Star Herbicide may be tank mixed with Quilt Fungicide for annual grass and broadleaf weed control and early season disease suppression. Apply Axial Star Herbicide at 16.4 fl. oz./A in a tank mix with Quilt Fungicide at 7 fl. oz./A. Refer to the Quilt Fungicide label for specific use directions, restrictions, and a list of diseases suppressed and/or controlled. Note: Under certain environmental conditions, tank mixes of Quilt Fungicide plus herbicides may cause crop injury.

Tank-Mix Application with Warrior II with Zeon Technology®

Axial Star Herbicide may be tank mixed with Warrior II with Zeon Technology for annual grass and broadleaf weed control and insect control. Apply Axial Star Herbicide at 16.4 fl. oz./A in a tank mix with Warrior II with Zeon Technology at labeled use rates. Refer to the Warrior II with Zeon Technology label for specific use directions, application rates, restrictions, and a list of insects controlled.

Mixtures with Liquid Nitrogen Fertilizers

Axial Star Herbicide may be mixed in a spray solution containing up to 50% liquid nitrogen fertilizer. Add Axial Star Herbicide to the water first. Mix thoroughly and then add the liquid nitrogen fertilizer in an amount no greater than 50% of the final volume. Note: Under certain environmental conditions, mixtures of liquid nitrogen fertilizers as a partial carrier may cause crop burn.

When using Axial Star Herbicide with approved herbicide tank-mix partners, consult the label of the partner product and follow any additional instructions or restrictions on that label which relate to mixture with liquid nitrogen fertilizers.

MANDATORY SPRAY DRIFT MANAGEMENT Aerial Applications: • Do not release spray at a height greater than 10 ft above the ground or vegetative canopy, unless a greater application height is necessary for pilot

-14- safety. • Applicators are required to use a medium or coarser droplet size (ASABE S572). • If the windspeed is 10 miles per hour or less, applicators must use ½ swath displacement upwind at the downwind edge of the field. When the windspeed is between 11-15 miles per hour, applicators must use ¾ swath displacement upwind at the downwind ed ge of the field. • Do not apply when wind speeds exceed 15 mph at the application site. If the windspeed is greater than 10 mph, the boom length must be 65% or less of the wingspan for fixed wing aircraft and 75% or less of the rotor diameter for helicopters. Otherwise, the boom length must be 75% or less of the wingspan for fixed-win g aircraft and 90% or less of the rotor diameter for helicopters. • Do not appl y during ground level temperature inversions.

Ground Boom Applications: • User must only apply with the release height recommended by the manufacturer, but no more than 4 feet above the ground or crop canopy. • Applicators are required to use a medium or coarser droplet size (ASABE S572). • Do not appl y when wind speeds exceed 15 miles per hour at the application site. • Do not apply during temperature inversions.

SPRAY DRIFT ADVISORIES THE APPLICATOR IS RESPONSIBLE FOR AVOIDING OFF-SITE SPRAY DRIFT. BE AWARE OF NEARBY NON-TARGET SITES AND ENVIRONMENTAL CONDITIONS. IMPORTANCE OF DROPLET SIZE An effective way to reduce spray drift is to apply large droplets. Use the largest droplets that provide target pest control. While applying larger droplets will reduce spray drift, the potential for drift will be greater if applications are made improperly or under unfavorable environmental conditions. Controlling Droplet Size – Ground Boom • Volume - Increasing the spray volume so that larger droplets are produced will reduce spray drift. Use the highest practical spray volume for the application. If a greater spray volume is needed, consider using a nozzle with a higher flow rate. • Pressure - Use the lowest spray pressure recommended for the nozzle to produce the target spray volume and droplet size. • Spray Nozzle - Use a spray nozzle that is designed for the intended application. Consider using nozzles designed to reduce drift.

-15- Controlling Droplet Size – Aircraft • Adjust Nozzles - Follow nozzle manufacturers’ recommendations for setting up nozzles. Generally, to reduce fine droplets, nozzles should be oriented parallel with the airflow in flight.

BOOM HEIGHT – Ground Boom For ground equipment, the boom should remain level with the crop and have minimal bounce. RELEASE HEIGHT - Aircraft Higher release heights increase the potential for spray drift. SHIELDED SPRAYERS Shielding the boom or individual nozzles can reduce spray drift. Consider using shielded sprayers. Verify that the shields are not interfering with the uniform deposition of the spray on the target area. TEMPERATURE AND HUMIDITY When making applications in hot and dry conditions, use larger droplets to reduce effects of evaporation. TEMPERATURE INVERSIONS Drift potential is high during a temperature inversion. Temperature inversions are characterized by increasing temperature with altitude and are common on nights with limited cloud cover and light to no wind. The presence of an inversion can be indicated by ground fog or by the movement of smoke from a ground source or an aircraft smoke generator. Smoke that layers and moves laterally in a concentrated cloud (under low wind conditions) indicates an inversion, while smoke that moves upward and rapidly dissipates indicates good vertical air mixing. Avoid applications during temperature inversions.

WIND

Drift potential generally increases with wind speed. AVOID APPLICATIONS DURING GUSTY WIND CONDITIONS.

Applicators need to be familiar with local wind patterns and terrain that could affect spray drift.

Boomless Ground Applications Setting nozzles at the lowest effective height will help to reduce the potential for spray drift

-16- Handheld Technology Applications Take precautions to minimize spray drift.

Sensitive Areas

This pesticide may only be applied when the potential for drift to adjacent sensitive areas, e.g., residential areas, bodies of water, non-target plants is minimal, (i.e., when the wind is blowing away from the sensitive area.)

Avoid all direct or indirect contact (such as spray drift) of Axial Star Herbicide with crops other than those specified for treatment on this label since injury may occur.

Chemigation

Do not apply this product through any type of irrigation system.

MIXING PROCEDURES

Prior to using Axial Star Herbicide, ensure that the spray tank, lines, screens and filters are thoroughly clean.

Mixing Instructions

1. Half fill spray tank with clean water. Start agitation or bypass system.
2. If a broadleaf herbicide mix partner is to be used, add the product FIRST prior to adding Axial Star Herbicide and agitate for 2-3 minutes.
3. Add correct amount of Axial Star Herbicide.
4. Agitate for 2-3 minutes before adding remainder of water and then maintain constant agitation.
5. After any break in spraying operations, a gitate thoroughly before spraying again.
6. Use the spray solution as soon as it is prepared.

Tank-Mix Compatibility Test

A jar test is recommended prior to tank mixing to ensure compatibility of Axial Star Herbicide with mixture partners. Add proportion amounts of tank mixture components in a clear quart jar one at a time in the recommended mixing order. Gently shake or invert capped jar and let stand for 15-30 minutes. If the mixture clumps, forms flakes, oily films or layers or other precipitates, it is not compatible and the tank mixture should not be used.

-17- CLEANOUT PROCEDURES FOR SPRAY EQUIPMENT

Thoroughly clean application equipment immediately after spraying Axial Star Herbicide. Ensure that all traces of the product are removed. The following directions are provided:

1. Drain any remaining spray mixture from the application equipment.
2. Hose down the interior surfaces of the tank. Flush tank, hoses, boom and nozzles with clean water for 10 minutes. Fill the tank with water and recirculate for 15 minutes. Spray the mixture through hoses, booms and nozzles and drain tank. Ensure that the area at the end of the spray boom beyond the last nozzle is flushed with water.
3. Remove all spray nozzles and screens and clean separately.
4. If spray equipment will be used for pesticide application to crops sensitive to Axial Star Herbicide, steps 1-2 should be repeated.
5. Exterior surfaces of spray equipment should also be thoroughly cleaned.

Note: Rinsate may be disposed of onsite according to label use directions or at an approved waste disposal facility.

STORAGE AND DISPOSAL

Do not contaminate water, food, or feed by storage or disposal.

Pesticide Storage

Store in a cool, dry, secure place. Do not store near seeds, fertilizers, or foodstuffs.

Pesticide Disposal

Pesticide wastes are toxic. Improper disposal of excess pesticides, spray mixture, or rinsate is a violation of Federal law. If these wastes cannot be disposed of by use according to label instructions, contact your State Pesticide or Environmental Control Agency, or the Hazardous Waste representative at the nearest EPA Regional Office for guidance.

-18- Container Handling (less than or equal to 5 gallons) Non-refillable container. Do not reuse or refill this container. Triple rinse container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank and drain for 10 seconds after the flow begins to drip. Fill the container ¼ full with water and recap. Shake for 10 seconds. Pour rinsate into application equipment or a mix tank or store rinsate for later use or disposal. Drain for 10 seconds after the flow begins to drip. Repeat this procedure two more times. Then offer for recycling if available or puncture and dispose of in a sanitary landfill, or by incineration, or by other procedures approved by state and local authorities.

Container Handling (greater than 5 gallons)

Non-refillable container. Do not reuse or refill this container. Triple rinse container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank. Fill the container ¼ full with water. Replace and tighten closures. Tip container on its side and roll it back and forth, ensuring at least one complete revolution, for 30 seconds. Stand the container on its end and tip it back and forth several times. Turn the container over onto its other end and tip it back and forth several times. Empty the rinsate into application equipment or a mix tank or store rinsate for later use or disposal. Repeat this procedure two more times. Then offer for recycling if available or puncture and dispose of in a sanitary landfill, or by incineration, or by other procedures approved by state and local authorities.

Container Handling (greater than 5 gallons)

Refillable container. Refill this container with pesticide only. Do not reuse this container for any other purpose. Cleaning the container before final disposal is the responsibility of the person disposing of the container. Cleaning before refilling is the responsibility of the person refilling. To clean container before final disposal, empty the remaining contents from this container into application equipment or mix tank. Fill the container about 10 percent full with water. Agitate vigorously or recirculate water with the pump for 2 minutes. Pour or pump rinsate into application equipment or rinsate collection system. Repeat this rinsing procedure two more times. Then offer for recycling if available or puncture and dispose of in a sanitary landfill, or by incineration, or by other procedures approved by state and local authorities.

For minor spills, leaks, etc., follow all precautions indicated on this label and clean up immediately. Take special care to avoid contamination of equipment and facilities during cleanup procedures and disposal of wastes. In the event of a major spill, fire, or other emergency, call 1-800-888-8372, day or night.

CONTAINER IS NOT SAFE FOR FOOD, FEED, OR DRINKING WATER!

Formulated with STARANE® Herbicide from Dow AgroSciences LLC.

-19- Amber®, Axial® Star, Axial® TBC, Axial® XL, Discover® NG, Orion®, Peak®, Pulsar™, Quilt®, Tilt®, Warrior II with Zeon Technology®, the ALLIANCE FRAME, the SYNGENTA Logo, and the PURPOSE ICON are Trademarks of a Syngenta Group Company.

Affinity™, Ally®, Express®, Finesse®, Harmony® Extra, Harmony® SG, and Viton® trademarks of E.I. du Pont de Nemours and Company

Bronate Advanced™, Buctril®, Bronate®, and Huskie™ trademarks of Bayer CropScience

Curtail® M trademark of Dow AgroSciences, LLC

©201X Syngenta

For non-emergency (e.g., current product information), call Syngenta Crop Protection at 1-800-334-9481

Manufactured for: Syngenta Crop Protection, LLC P.O. Box 18300 Greensboro, North Carolina 27419-8300

SCP 1389A

Axial Star 1389 MAS 0813 AMEND-E.DEC2020-CL – ep – 1/20/2026 000100-01389.20201215E.Axial_Star.AMEND.DEC2020-CL