crop-chem-docs/corpus/epa_ppls/100-1410.md

Zemax® Selective Herbicide

• EPA Reg No: 100-1410
• Registrant: SYNGENTA CROP PROTECTION, LLC
• Signal word: Caution
• Active ingredients: S-Metolachlor (36.8%); Mesotrione (3.68%)
• Label accepted: 2023-01-05
• Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000100-01410-20230105.pdf

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UNITED STATES ENVIRONMENTAL PROTECTION AGENCY WASHINGTON, DC 20460

OFFICE OF CHEMICAL SAFETY AND POLLUTION PREVENTION

January 5, 2023

Amanda Foderaro Regulatory Manager Syngenta Crop Protection, LLC P.O. Box 18300 Greensboro, NC 27419

Subject: Registration Review Label Amendments Incorporating Mitigation Measures from the Interim Decisions for S-Metolachlor and Mesotrione and the National Marine Fisheries Services’ (NMFS) Biological Opinion on the Effects of S-Metolachlor on Pacific Salmonids Product Name: ZEMAX SELECTIVE HERBICIDE EPA Registration Number: 100-1410 Application Dates: 29-Mar-2022 and 03-Sep-2021 Decision Numbers: 582927, 578271 and 576427

Dear Amanda Foderaro:

The Agency, in accordance with the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA), as amended, has completed reviewing all the information submitted with your application to support the Registration Review of the above referenced product in connection with the S-Metolachlor and Mesotrione Interim Decisions. The Agency has concluded that your submission is acceptable.

This letter also addresses the label mitigation resulting from the NMFS’ Biological Opinion on the effects of S-Metolachlor on Pacific salmonids. The Agency has concluded that your submission is also acceptable. The label referred to above, submitted in connection with registration under FIFRA, as amended, is acceptable.

Should you wish to add/retain a reference to the company’s website on your label, then please be aware that the website becomes labeling under the Federal Insecticide Fungicide and Rodenticide Act and is subject to review by the Agency. If the website is false or misleading, the product would be misbranded and unlawful to sell or distribute under FIFRA section 12(a)(1)(E). 40 CFR 156.10(a)(5) list examples of statements EPA may consider false or misleading. In addition, regardless of whether a website is referenced on your product’s label, claims made on the website may not substantially differ from those claims approved through the registration process. Therefore, should the Agency find or if it is brought to our attention that a website contains false or misleading statements or claims substantially differing from the EPA approved registration, the website will be referred to the EPA’s Office of Enforcement and Compliance.

Page 2 of 2 EPA Reg. No. 100-1410 Decision No. 582927, 578271 and 576427

A stamped copy of your labeling is enclosed for your records. This labeling supersedes all previously accepted labeling. You must submit one copy of the final printed labeling before you release the product for shipment with the new labeling. In accordance with 40 CFR 152.130(c), you may distribute or sell this product under the previously approved labeling for 12 months from the date of this letter. After 12 months, you may only distribute or sell this product if it bears this new revised labeling or subsequently approved labeling. “To distribute or sell” is defined under FIFRA section 2(gg) and its implementing regulation at 40 CFR 152.3.

If you have any questions about this letter, please contact Srijana Shrestha at shrestha.srijana@epa.gov.

Sincerely,

Linda Arrington, Branch Chief Risk Management and Implementation Branch 4 Pesticide Re-Evaluation Division Office of Pesticide Programs

Enclosure: Stamped Label

Sale, use, and distribution of this product in Nassau and Suffolk Counties in the State of New York is prohibited. S-METOLACHLOR GROUP 15 HERBICIDE MESOTRIONE GROUP 27 HERBICIDE Zemax® Selective Herbicide A Preemergence and Postemergence Herbicide for Control of Annual Grass and Broadleaf Weeds in Field Corn, Seed Corn, Sweet Corn, Yellow Popcorn and Grain Sorghum Active Ingredients*: S-metolachlor: (CAS No . 87392-12-9).................................................................. 36.80% Mesotrione: (CAS No . 104206-82-8) ..................................................................... 3.68% Other Ingredients: 59.52% Total: 100.00% *Active ingredients per gallon: S-metolachlor 3.34 pounds, mesotrione 0.33 pounds. KEEP OUT OF REACH OF CHILDREN. CAUTION See additional precautionary statements and directions for use inside booklet. EPA Reg. No. 100-1410 EPA Est. SCP 1410 ___ gallons [bulk] Net Contents 2.5 gallons Net Contents 220 gallons Net Contents Jan 05, 2023 100-1410

-2- FIRST AID If in eyes x Hold eye open and rinse slowly and gently with water for 15-20 minutes. x Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye. x Call a poison control center or doctor for treatment advice. If swallowed x Call a poison control center or doctor immediately for treatment advice. x Have person sip a glass of water if able to swallow. x Do not induce vomiting unless told to do so by the poison control center or doctor. x Do not give anything by mouth to an unconscious person. If on skin or clothing x Take off contaminated clothing. x Rinse skin immediately with plenty of water for 15-20 minutes. x Call a poison control center or doctor for treatment advice. If inhaled x Move person to fresh air. x If person is not breathing, call 911 or an ambulance, then give artificial respiration, preferably by mouth-to-mouth, if possible. x Call a poison control center or doctor for further treatment advice. Have the product container or label with you when calling a poison control center or doctor, or going for treatment. HOTLINE NUMBER For 24 Hour Medical Emergency Assistance (Human or Animal) or Chemical Emergency Assistance (Spill, Leak, Fire or Accident), Call 1-800-888-8372 PRECAUTIONARY STATEMENTS Hazards to Humans and Domestic Animals CAUTION Causes moderate eye irritation. Avoid contact with eyes or clothing. Wear protective eyewear. Remove and wash contaminated clothing before reuse. Wash thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco, or using the toilet.

-3- Personal Protective Equipment (PPE) Mixers, Loaders, Applicators and other handlers must wear: x Protective eyewear x Long-sleeved shirt and long pants x Chemical-resistant gloves made of barrier laminate, butyl rubber >14 mils, nitrile rubber >14 mils, neoprene rubber >14 mils, natural rubber >14 mils, polyethylene, polyvinyl chloride (PVC) >14 mils, or Viton® >14 mils x Shoes plus socks Follow manufacturer's instructions for cleaning/maintaining PPE. If no such instructions for washables, use detergent and hot water. Keep and wash PPE separately from other laundry. User Safety Recommendations Users should: x Wash hands before eating, drinking, chewing gum, using tobacco, or using the toilet. x Remove clothing/PPE immediately if pesticide gets inside. Then wash thoroughly and put on clean clothing. x Remove PPE immediately after handling this product. Wash the outside of gloves before removing. As soon as possible, wash thoroughly and change into clean clothin g. Engineering Controls When handlers use closed systems or enclosed cabs, in a manner that meets the requirements listed in the Worker Protection Standard (WPS) for agricultural pesticides (40 CFR 170.240(d)(4-6)), the handler PPE requirements may be reduced or modified as specified in the WPS. Environmental Hazards For terrestrial uses: Do not apply directly to water, to areas where surface water is present or to intertidal areas below the mean high water mark. Do not contaminate water when disposing of equipment washwater or rinsate. GROUNDWATER ADVISORY The active ingredients, S-metolachlor and mesotrione, are known to leach through soil into groundwater under certain conditions as a result of label use. These chemicals may leach into groundwater if used in areas where soils are permeable, particularly where the water table is shallow.

-4- SURFACE WATER ADVISORY The product may impact surface water quality due to runoff of rain water or through ground spray drift. This is especially true for poorly draining soils and soils with shallow groundwater. This product is classified as having high potential for reaching surface water via runoff for several months or more after application. A level, well maintained vegetative buffer strip between areas to which this product is applied and surface water features such as ponds, streams, and springs will reduce the potential loading of S-metolachlor and mesotrione from runoff water and sediment. Runoff of this product will be reduced by avoiding applications when rainfall or irrigation is expected to occur within 48 hours. NON-TARGET ORGANISM ADVISORY This product is toxic to plants and may adversely impact the forage and habitat of non- target organisms, including pollinators, in areas adjacent to the treated site. Protect the forage and habitat of non-target organisms by following label directions intended to minimize spray drift. Reporting Ecological Incidents To report ecological incidents, including mortality, injury, or harm to plants and animals, call 1-800-888-8372. Mixing/Loading Instructions Care must be taken when using this product to prevent back siphoning into wells, spills, or improper disposal of excess pesticide, spray mixtures, or rinsates. Check valves or antisiphoning devices must be used on mixing equipment. This product may not be mixed/loaded or used within 50 ft. of wells, including abandoned wells, drainage wells, and sink holes. Operations that involve mixing, loading, rinsing, or washing of this product into or from pesticide handling or application equipment or containers within 50 ft. of any well are prohibited, unless conducted on an impervious pad constructed to withstand the weight of the heaviest load that may be positioned on or moved across the pad. Such a pad shall be designed and maintained to contain any product spills or equipment leaks, container or equipment rinse or wash water, and rain water that may fall on the pad. Surface water shall not be allowed to either flow over or from the pad, which means the pad must be self-contained. The pad shall be sloped to facilitate material removal. An unroofed pad shall be of sufficient capacity to contain at a minimum 110% of the capacity of the largest pesticide container or application equipment on the pad. A pad that is covered by a roof of sufficient size to completely exclude precipitation from contact with the pad shall have a minimum

-5- containment capacity of 100% of the capacity of the largest pesticide container or application equipment on the pad. Containment capacities as described above shall be maintained at all times. The above-specified minimum containment capacities do not apply to vehicles when delivering pesticide shipments to the mixing/loading site. Physical and Chemical Hazards Do not use or store near heat or open flame.

-6- CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY NOTICE: Read the entire Directions for Use and Conditions of Sale and Limitation of Warranty and Liability before buying or using this product. If the terms are not acceptable, return the product at once, unopened, and the purchase price will be refunded. The Directions for Use of this product must be followed carefully. It is impossible to eliminate all risks inherently associated with the use of this product. Crop injury, ineffectiveness or other unintended consequences may result because of such factors as manner of use or application, weather or crop conditions, presence of other materials or other influencing factors in the use of the product, which are beyond the control of SYNGENTA CROP PROTECTION, LLC or Seller. To the extent permitted by applicable law, Buyer and User agree to hold SYNGENTA and Seller harmless for any claims relating to such factors. SYNGENTA warrants that this product conforms to the chemical description on the label and is reasonably fit for the purposes stated in the Directions for Use, subject to the inherent risks referred to above, when used in accordance with directions under normal use conditions. To the extent permitted by applicable law: (1) this warranty does not extend to the use of the product contrary to label instructions or under conditions not reasonably foreseeable to or beyond the control of Seller or SYNGENTA, and, (2) Buyer and User assume the risk of any such use. To the extent permitted by applicable law, SYNGENTA MAKES NO WARRANTIES OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE NOR ANY OTHER EXPRESS OR IMPLIED WARRANTY EXCEPT AS WARRANTED BY THIS LABEL. To the extent permitted by applicable law, in no event shall SYNGENTA be liable for any incidental, consequential or special damages resulting from the use or handling of this product. TO THE EXTENT PERMITTED BY APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE USER OR BUYER, AND THE EXCLUSIVE LIABILITY OF SYNGENTA AND SELLER FOR ANY AND ALL CLAIMS, LOSSES, INJURIES OR DAMAGES (INCLUDING CLAIMS BASED ON BREACH OF WARRANTY, CONTRACT, NEGLIGENCE, TORT, STRICT LIABILITY OR OTHERWISE) RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, SHALL BE THE RETURN OF THE PURCHASE PRICE OF THE PRODUCT OR, AT THE ELECTION OF SYNGENTA OR SELLER, THE REPLACEMENT OF THE PRODUCT. SYNGENTA and Seller offer this product, and Buyer and User accept it, subject to the foregoing Conditions of Sale and Limitation of Warranty and Liability, which may not be modified except by written agreement signed by a duly authorized representative of SYNGENTA.

-7- DIRECTIONS FOR USE It is a violation of Federal law to use this product in a manner inconsistent with its labeling. Endangered Species Protection Requirements It is a Federal offense to use any pesticide in a manner that results in an unauthorized “take” (e.g., kill or otherwise harm) of an endangered species and certain threatened species, under the Endangered Species Act section 9. When using this product, you must follow the measures contained in the Endangered Species Protection Bulletin for the area in which you are applying the product. You must obtain a Bulletin no earlier than six months before using this product. To obtain Bulletins, consult http://www.epa.gov/espp/, call 1-844-447-3813, or email ESPP@epa.gov. You must use the Bulletin valid for the month in which you will apply the product. Do not apply this product in a way that will contact workers or other persons, either directly or through drift. Only protected handlers may be in the area during application. For any requirements specific to your State or Tribe, consult the agency responsible for pesticide regulation.

-8- AGRICULTURAL USE REQUIREMENTS Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR part 170. This Standard contains requirements for the protection of agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of agricultural pesticides. It contains requirements for training, decontamination, notification, and emergency assistance. It also contains specific instructions and exceptions pertaining to the statements on this label about personal protective equipment (PPE), and restricted-entry interval. The requirements in this box only apply to uses of this product that are covered by the Worker Protection Standard. Do not enter or allow worker entry into treated areas during the restricted-entry interval (REI) of 24 hours. Exception: If the product is soil-injected or soil- incorporated, the Worker Protection Standard, under certain circumstances, allows workers to enter the treated area if there will be no contact with anything that has been treated. For early entry to treated areas that is permitted under the Worker Protection Standard and that involves contact with anything that has been treated, such as plants, soil and water, wear: x Protective eyewear x Coveralls x Chemical-resistant gloves made of barrier laminate, butyl rubber >14 mils, nitrile rubber >14 mils, neoprene rubber >14 mils, natural rubber >14 mils, polyethylene, polyvinyl chloride (PVC) >14 mils, or Viton >14 mils x Shoes and socks FAILURE TO FOLLOW THE DIRECTIONS FOR USE AND PRECAUTIONS ON THIS LABEL MAY RESULT IN POOR WEED CONTROL, CROP INJURY, OR ILLEGAL RESIDUES. Note: It is illegal to sell, use or distribute this product within, or into, Nassau County or Suffolk County, New York.

-9- PRODUCT INFORMATION Zemax is used in field corn and seed corn for preemergence and early postemergence control of many annual grass and broadleaf weeds. Zemax is also used in yellow popcorn, sweet corn and grain sorghum for preemergence control of many annual grass and broadleaf weeds. See Tables 1 and 2 for a list of weeds controlled. This product must be used prior to weed emergence to effectively control most grass weeds. Applied according to use directions and under normal growing conditions, Zemax will not harm the treated crop. During germination and early stages of growth, environmental conditions or other factors that favor poor or slow growth can weaken crop seedlings. Zemax used under these conditions can result in crop injury. Use Restrictions and Precautions

1. Do not apply this product thro ugh any type of irrigation system.
2. Do not use flood irrigation to apply or incorporate this product.
3. Do not use aerial application to apply Zemax.
4. Do not contaminate irrigation water used for non-labeled crops or water used for domestic purposes.
5. Do not apply under conditions which favor runoff or wind erosion of soil containing this product to non-target areas.
6. To prevent off-site movement due to runoff or wind erosion: a. Avoid treating powdery dry or light sandy soils when conditions are favorable for wind erosion. Under these conditions, the soil surface should first be settled by rainfall or irrigation. b. Do not apply to impervious substrates such as paved or highly compacted surfaces or frozen or snow covered soils. WEED RESISTANCE MANGEMENT Zemax is a combination of mesotrione and S-metolachlor (Group 15 and 27 Herbicides) and can be an effective component of a weed resistance management strategy. Naturally occurring biotypes of certain broadleaf weed species with resistance to triazines, ALS, PPO, Glycine (glyphosate) and HPPD herbicides are known to exist. If

-10- biotypes of weeds resistant to triazines, ALS, PPO and glycine inhibitors are present in the field, this herbicide should control them if they are listed in Tables 1 and 2. Scout and know your field • Know weed species present in the field to be treated through scouting and field history. An understanding of weed biology is useful in designing a resistance management strategy. Ensure the weed management program will control all weeds present. • Fields should be scouted prior to application to determine species present and growth stage. Always apply this herbicide at the full labeled rate and correct timing for the weeds present in the field. Utilize non-herbicidal practices to add diversity • Use diversified management tactics su ch as cover crops, mechanical weed control, harvest weed seed control, and crop rotation as appropriate. Use good agronomic practices, start clean and stay clean • Use good agronomic practices that enhance crop competitiveness. • Plant into weed-free fields utilizing tillage or an effective burndown herbicide for control of emerged weeds. • Sanitize farm equipment to avoid spreading seed or vegetative propagules prior to leaving fields. Difficult to control weeds • Fields with difficult to control weeds should be planted in rotation with crops that allow the use of herbicides with an alternative mode of action or different management practices. • Difficult to control weeds may require sequential applications, such as a broad spectrum preemergence herbicide followed by one or more postemergence herbicide applications. Utilize herbicides containing different modes of action effective on the target weeds in sequential applications. Do not overuse the technology • Do not use more than two applications of this or any other herbicide with the same mode of action in a single growing season unless mixed with an herbicide with a different mode of action which provides overlapping spectrum for the difficult to control weeds. Scout and inspect fields following application • Prevent an influx of weeds into the field by controlling weeds in field borders. • Scout fields after application to verify that the treatment was effective. • Suspected- herbicide resistant weeds may be identified by these indicators

-11- • Failure to control a weed species normally controlled by the herbicide at the dose applied, especially if control is achieved on adjacent weeds; • A spreading patch of non-controlled plants of a particular weed species; and • Surviving plants mixed with controlled individuals of the same species. • Report non-performance of this product to your Syngenta retailer, Syngenta representative, or call 1-866-Syngent(a) (866-796-4368). If resistance is suspected ensure weed escapes are controlled using an herbicide with an effective mode of action and/or use non-chemical means to prevent further seed production. Prevent weed escapes before, during, and after harvest • Do not allow weed escapes to produce seed or vegetative structures such as tubers or stolons which contribute to spread and survival. Consider harvest weed seed management and control weeds post-harvest to prevent seed production. Resistant Weeds • Contact your local Syngenta representative, retailer, crop advisor or extension agent to determine if weeds resistant to modes of action contained in this product are present in your area. • Do not assume that each listed weed is being controlled by multiple modes of action. Premixes are intended to broaden the spectrum of weeds that are controlled. Some weeds may be controlled by only one of the active ingredients in this product. • If resistant biotypes have been reported, use the full labeled rate of this product, apply at the labeled timing, and tank-mix with an additional different mode of action product so there are multiple effective modes of application for each suspected resistant weed.

-12- APPLICATION INFORMATION Ground Application MANDATORY SPRAY DRIFT MANAGEMENT Ground Boom Applications: • Do not release spray at a height greater than 3 feet above the ground or crop canopy. • Applicators are required to select the nozzles and pressure that deliver medium or coarser droplets in accordance with American Society of Agricultural & Biological Engineers Standard 572 (ASABE S572). • Do not apply when wind speeds exceed 15 miles per hour at the application site. • Do not apply during temperature inversions. Boomless Ground Applications: • Applicators are required to select the nozzle and pressure that deliver medium or coarser droplet size in accordance with American Society of Agricultural & Biological Engineers Standard 572 (ASABE S572.3). • Do not apply when wind speeds exceed 15 miles per hour at the application site. • Do not apply during temperature inversions. Ensure that all in-line strainer and nozzle screens in the sprayer are 50-mesh or coarser. Always ensure that agitation is maintained until spraying is completed, even if stopped for brief periods of time. If the agitation is stopped for more than 5 minutes, resuspend the spray solution by running on full agitation prior to spraying. Preemergence Applications Apply Zemax preemergence with a carrier volume of 10-80 gals./A. Postemergence Applications Apply in a spray volume of 10-30 gals./A. When weed foliage is dense, use a minimum spray volume of 20 gals/A. Flat fan nozzles are recommended for optimum postemergence coverage. Do not use floodjet or venturi type nozzles or controlled droplet application equipment for postemergence applications. Use only clean water as the carrier when applying Zemax after crop emergence. Aerial Application Do not use aerial application to apply Zemax.

-13- SPRAY DRIFT ADVISORIES THE APPLICATOR IS RESPONSIBLE FOR AVOIDING OFF-SITE SPRAY DRIFT. BE AWARE OF NEARBY NON-TARGET SITES AND ENVIRONMENTAL CONDITIONS. IMPORTANCE OF DROPLET SIZE An effective way to reduce spray drift potential is to apply larger droplets. Use the largest droplets that provide target pest control. While applying larger droplets will reduce spray drift, the potential for drift will be greater if applications are made improperly or under unfavorable environmental conditions. CONTROLLING DROPLET SIZE – GROUND BOOM x Volume - Increasing the spray volume so that larger droplets are produced will reduce spray drift. Use the highest practical spray volume for the application. If a greater spray volume is needed, consider using a nozzle with a higher flow rate. x Pressure - Use the lowest spray pressure recommended for the nozzle to produce the target spray volume and droplet size. x Spray Nozzle - Use a spray nozzle that is designed for the intended application. Consider using nozzles designed to reduce drift. BOOM HEIGHT x For ground equipment, the boom should remain level with the crop and have minimal bounce. BOOMLESS GROUND APPLICATIONS x Setting nozzles at the lowest effective height will help to reduce the potential for spray drift. SHIELDED SPRAYERS x Shielding the boom or individual nozzles can reduce spray drift. Consider using shielded sprayers. Verify that the shields are not interfering with the uniform deposition of the spray on the target area. TEMPERATURE AND HUMIDITY x When making applications in hot and dry conditions, use larger droplets to reduce effects of evaporation. TEMPERATURE INVERSIONS x Drift potential is high during a temperature inversion. x Temperature inversions are characterized by increasing temperature with altitude and are common on nights with limited cloud cover and light to no wind. The presence of an inversion can be indicated by ground fog or by the movement of smoke from a ground source or an aircraft smoke generator. Smoke that layers

-14- and moves laterally in a concentrated cloud (under low wind conditions) indicates an inversion, while smoke that moves upward and rapidly dissipates indicates good vertical air mixing. x Avoid applications during temperature inversions. WIND x Drift potential generally increases with wind speed. x AVOID APPLICATIONS DURING GUSTY WIND CONDITIONS. x Applicators need to be familiar with local wind patterns and terrain that could affect spray drift. Sensitive Areas x Zemax herbicide should only be applied when the potential for drift to adjacent sensitive areas (e.g., residential areas, bodies of water, known habitat for threatened or endangered species, nontarget crops) is minimal (e.g., when wind is blowing away from the sensitive areas). ADDITIVES Applications After Corn Has Emerged When applying Zemax postemergence to corn, add either a non-ionic surfactant (NIS) or crop oil concentrate (COC). When using a NIS, add at 0.25% v/v (1 qt./100 gals.). When using a COC, add at a rate of 1% v/v (1 gal./100 gals.) or the equivalent of 1 gal./100 gals. The use of COC will provide more consistent weed control than an NIS but may also result in temporary crop injury. In addition to NIS or COC, a nitrogen based adjuvant may also be added to increase consistency of weed control. The use of nitrogen based adjuvants (AMS or UAN) will increase the risk of crop injury and can result in temporary crop injury. Do not use methylated seed oil (MSO) with Zemax when applied alone to emerged field corn, or when Zemax is applied as a postemergence tank mixture with other products. Applications Prior to Corn Emergence Any of the adjuvants may be used at a preemergence or preplant timing, i.e. where the corn crop has not yet emerged, to increase burndown activity on existing weeds. MIXING PROCEDURES Either water or liquid fertilizers excluding suspension fertilizers may be used as carriers for preemergence applications. If fluid fertilizers are used, a compatibility test must be done. Even if Zemax is physically compatible with a fluid fertilizer, constant agitation is necessary to maintain a uniform mixture during application. Use only clean water as the

-15- carrier when applying Zemax after crop emergence. The spray tank must be clean, thoroughly rinsed and decontaminated before adding either Zemax alone or with tank-mix partners. If water is used as the carrier, use clean water. Always refer to labels of other pesticide products for mixing directions and precautions which may differ from those outlined here. Use in accordance with the most restrictive of label limitations and precautions. No label dosage rates should be exceeded. This product cannot be mixed with any product containing a label prohibition against such mixing. Do not tank mix Zemax with any other insecticide, fungicide, fertilizer solution, or adjuvant not recommended on the label without testing compatibility, as poor mixing may result. It is recommended that the compatibility of any tank-mix combination be tested on a small scale such as a jar test before actual tank mixing. Use the Following Mixing Instructions for Adding Zemax to the Spray Tank

1. Only use sprayers in good operating condition with adequate agitation. Ensure the sprayer is cleaned according to instructions on label of the product used prior to use of Zemax.
2. Begin to fill sprayer tank or premix tank with clean water and engage agitator. Agitation must be continued throughout the entire mixing and spraying procedure.
3. When the sprayer or premix tank is half full of water, begin to add the mixture components
4. If ammonium sulfate (AMS) is used, continue agitation until completely dispersed.
5. If a wettable powder or dry flowable formulation is used, add it slowly to the tank. Mixing and compatibility may be improved when a wettable powder or dry flowable is diluted with water before adding to the tank. Agitate during the procedure.
6. If a flowable formulation is used, add slowly to the tank.
7. Add Zemax slowly to the tank.
8. Add any other liquid tank-mix products next with emulsifiable concentrates last.
9. Add an adjuvant last, if needed.
10. Complete filling the sprayer tank and continue agitation.

-16- 11. Apply as soon as possible after spray mixture is prepared. Do not leave mixture in spray tank overnight without agitation. If Zemax is added to the spray tank via induction, compatibility may be compromised. If an induction tank (or similar equipment) is used, add each product separately and allow each to disperse into the spray tank before adding the next product. For best tank-mix compatibility, rinse the induction tank with water before adding each component. It is recommended that Zemax not be added to the spray tank via in-line injection. Compatibility Test A compatibility test is recommended before tank mixing to ensure compatibility of Zemax with fertilizer carriers or other pesticides. The following test assumes a spray volume of 25 gals./A. For other spray volumes, make appropriate changes in the ingredients. Nitrogen solutions or complete liquid fertilizers, excluding suspension fertilizers, may replace all or part of the water in the spray. Because liquid fertilizers vary, even within the same analysis, always check compatibility with pesticide(s) before use. Incompatibility of tank mixtures is more common with mixtures of fertilizer and pesticides. Compatibility Test Procedure

1. Add 1.0 pt. of carrier (fertilizer or water) to each of two 1 qt. jars with tight lids. Use the same source of water that will be used for the tank mix and conduct the test at the temperature the tank mix will be applied.
2. To one of the jars, add ¼ tsp. or 1.2 milliliters of a compatibility agent approved for this use (¼ tsp. is equivalent to 2.0 pts./100 gals. spray). Shake or stir gently to mix.
3. To both jars, add the appropriate amount of pesticide(s) in their relative proportions based on recommended label rates. If more than one pesticide is used, add them separately as described in the Mixing Procedures section of this label. After each addition, shake or stir gently to thoroughly mix.
4. After adding all ingredients, put lids on and tighten, and invert each jar ten times to mix. Let the mixtures stand 15-30 minutes and then look for separation, large flakes, precipitates, gels, heavy oily film on the jar, or other signs of incompatibility. Determine if the compatibility agent is needed in the spray mixture by comparing the two jars. If either mixture separates, but can be remixed readily, the mixture can be sprayed as long as good agitation is used. If the mixtures are incompatible, test the following methods of improving compatibility: (a) slurry the dry pesticide(s) in water before addition, or (b) add ½

-17- the compatibility agent to the fertilizer or water and the other ½ to the emulsifiable concentrate or flowable pesticide before addition to the mixture. If incompatibility is still observed, do not use the mixture. 5. After compatibility testing is complete , dispose of any pesticide wastes in accordance with the Storage and Disposal section in this label. Cleaning Equipment After Application Special attention must be given to cleaning equipment before spraying a crop other than field corn. Mix only as much spray solution as needed. Equipment Cleaning Procedure

1. Flush tank, hoses, boom, and nozzles with clean water.
2. Prepare a cleaning solution of 1 gal. of household ammonia per 25 gals. of water. Many commercial spray tank cleaners may be used.
3. Use a pressure washer to clean the inside of the spray tank with this solution. Take care to wash all parts of the tank, including the inside top surface. If a pressure washer is not available, completely fill the sprayer with the cleaning solution to ensure contact of the cleaning solution with all internal surfaces of the tank and plumbing. Start agitation in the sprayer and thoroughly recirculate the cleaning solution for at least 15 minutes. All visible deposits must be removed from the spraying system.
4. Flush hoses, spray lines, and nozzles for at least 1 minute with the cleaning solution.
5. Remove boom end caps and flush dead space areas, with water, then replace caps.
6. Dispose of rinsate from steps 1-5 in an appropriate manner, according to all local State and federal regulations.
7. Repeat steps 2-6.
8. Remove nozzles, screens, and strainers and clean separately in the ammonia solution after completing the above procedures.
9. Rinse the complete spraying system with clean water.

-18- WEEDS CONTROLLED Zemax applied as directed in this label will control or suppress the weeds listed in Tables 1 and 2. Optimum weed control will be obtained if Zemax is applied according to all label directions. If a significant rainfall does not occur within 7 days after a preemergence application, weed control may be decreased. When weeds are stressed or not actively growing due to drought, heat, lack of fertility, flooding, or prolonged cool temperatures, postemergence control can be reduced or delayed. Table 1. Weeds Controlled or Partially Controlled Preemergence by Zemax Common Name Scientific Name C = Control PC = Partial Control Amaranth, Palmer Amaranthus palmeri C Amaranth, Powell Amaranthus powellii C Barnyardgrass Echinochloa crus-galli C Buffalobur Solanum rostratum C Carpetweed Mollugo verticillata C Cocklebur, common Xanthium strumarium PC Crabgrass, large Digitaria sanguinalis C Crowfootgrass Dactyloctenium aegyptium C Cupgrass, prairie Eriochloa contracta C Cupgrass, Southwestern Eriochloa acuminata C Cupgrass, woolly Eriochloa villosa PC Foxtail, giant Setaria faberi C Foxtail, green Setaria viridis C Foxtail, robust (purple, white) Setaria viridis C Foxtail, yellow Setaria pumila C Galinsoga Galinsoga parviflora C Goosegrass Eleusine indica C Jimsonweed Datura stramonium C Johnsongrass, seedling Sorghum halepense PC Kochia Kochia scoparia PC Lambsquarters, common Chenopodium album C Millet, foxtail Setaria italica C Millet, wild proso Panicum miliaceum PC Morningglory, ivyleaf Ipomoea hederacea PC Morningglory, entireleaf Ipomoea hederacea PC Nightshade, black Solanum nigrum C Nightshade, Eastern black Solanum ptycanthum C

-19- Common Name Scientific Name C = Control PC = Partial Control Nightshade, hairy Solanum sarachoides C Nutsedge, yellow Cyperus esculentus C Panicum, browntop Panicum fasciculatum C Panicum, fall Panicum dichotomiflorum C Panicum, Texas Panicum texanum PC Pigweed, redroot Amaranthus retroflexus C Pigweed, smooth Amaranthus hybridus C Purslane, common Portulaca oleracea C Pusley, Florida Richardia scabra C Ragweed, common Ambrosia artemisiifolia PC Ragweed, giant Ambrosia trifida PC Rice, red Oryza sativa C Sandbur, field Cenchrus incertus PC Shattercane Sorghum bicolor PC Sida, prickly Sida spinosa PC Signalgrass, broadleaf Brachiaria platyphylla PC Smartweed, ladysthumb Polygonum persicaria C Smartweed, Pennsylvania Polygonum pensylvanicum C Sprangletop, red Leptochloa filiformis C Velvetleaf Abutilon theophrasti C Waterhemp, common Amaranthus rudis C Waterhemp, tall Amaranthus tuberculatus C Witchgrass Panicum capillare C Table 2: Weeds Controlled or Partially Controlled by Early Postemergence Applications of Zemax Zemax applied early postemergence will provide control or partial control of small emerged broadleaf weeds (less than 3 inches) but will not provide consistent or effective control of weeds identified as resistant to postemergence HPPD inhibitors. Common Name Scientific Name C = Control PC = Partial Control Amaranth, Palmer Amaranthus palmeri C Amaranth, Powell Amaranthus powellii C Buffalobur Solanum rostratum C Carpetweed Mollugo verticillata C Cocklebur, common Xanthium strumarium C Dandelion Taraxacum officinale PC Galinsoga Galinsoga parviflora C Hemp Cannabis sativa C Horsenettle Solanum carolinense C Horseweed (marestail) Conyza canadensis C

-20- Common Name Scientific Name C = Control PC = Partial Control Jimsonweed Datura stramonium C Kochia Kochia scoparia PC Lambsquarters, common Chenopodium album C Morningglory, entireleaf Ipomoea hederacea PC Morningglory, ivyleaf Ipomoea hederacea PC Mustard, wild Brassica kaber C Nightshade, black Solanum nugrum C Nightshade, Eastern black Solanum ptycanthum C Nightshade, hairy Solanum sarachoides C Nutsedge, yellow Cyperus esculentus PC Pigweed, redroot Amaranthus retroflexus C Pigweed, smooth Amaranthus hybridus C Pokeweed Phytolacca americana C Potatoes, volunteer Solanum spp. C Purslane, common Portulaca oleracea PC Pusley, Florida Richardia scabra C Ragweed, common Ambrosia artemisiifolia C Ragweed, giant Ambrosia trifida C Sida, prickly Sida spinosa PC Smartweed, ladysthumb Polygonum persicaria C Smartweed, Pennsylvania Polygonum pensylvanicum C Thistle, Canada Cirsium arvense PC Velvetleaf Abutilon theophrasti C Waterhemp, common Amaranthus rudis C Waterhemp, tall Amaranthus tuberculatus C ROTATIONAL CROPS When Zemax is applied as directed on this label, follow the crop rotation intervals in Table 3. If Zemax is tank mixed with other products, follow the most restrictive product’s crop rotation interval.

-21- Table 3. Crop Rotational Intervals Crop Rotational Interval 1 All corn types and grain sorghum2 Anytime Cereals (barley, oats, rye, wheat) 4.5 months Cotton, peanuts, potatoes, and soybeans The sprin g following application Beans (dry and snap), cucurbits, peas, red clover, sugar beets, tomatoes and all other rotational crops 18 months 1Time between Zemax application and replanting of the rotational crop 2Grain sorghum must be seed treated with a safener to tolerate S-metolachlor CORN USE DIRECTIONS Apply Zemax for preemergence control of many annual grass and broadleaf weeds in field corn, seed corn, sweet corn and yellow popcorn. Zemax may also be applied early postemergence for the control of broadleaf weeds in field corn and seed corn. Do not apply Zemax to yellow popcorn or sweet corn after the crop has emerged, or crop injury may occur. Refer to Tables 1 and 2 for a list or weeds controlled or partially controlled by Zemax. Zemax Application Timings Burndown for Reduced Tillage Situations In reduced or no-till corn and before the crop has emerged, Zemax can be applied alone or in tank mixture with Gramoxone Inteon, Touchdown brands, Roundup brands or other registered herbicide for burndown of existing weeds. Refer to Tables 1 and 2 for specific weeds controlled by Zemax. Read and follow all product labels for specific use directions and information on weeds controlled. Refer to the ADDITIVES and TANK MIX sections on this label for additional recommendations. Early Preplant and Preemergence Zemax may be applied early preplant (up to 14 days prior to planting) or preemergence in field corn, seed corn, sweet corn and yellow popcorn. Postemergence Zemax may be applied in field or seed corn after emergence until the plants reach 30 inches in height or up to the 8-leaf stage of corn growth. Use only clean water as the carrier when applying Zemax after crop emergence. Do not apply postemergence in liquid fertilizer or severe crop injury will occur. Do not apply Zemax to emerged yellow popcorn or sweet corn, or severe crop injury may occur. Refer to the ADDITIVES section on this label for burndown adjuvant recommendations.

-22- Zemax Use Rates Apply Zemax at a rate of 2.0-2.4 qts./A for control or partial control of the weeds listed in Tables 1 and 2. The soil organic matter content of the field on which Zemax is to be applied must be known. Table 4. Zemax Use Rates in Corn % Or ganic Matter Zemax Use Rate <3% 2.0 qts./A

3% 2.4 qts./A Zemax is not recommended on soils with greater than 10% organic matter or poor weed control may result. Tank-Mix Combinations Preemergence (Applied Before the Crop has Emerged) Tank-mix partners listed in Table 5 may be used in conventional, reduced, or no-till systems and be applied by the same methods and at the same timings as Zemax unless otherwise specified in the tank-mix product label. Follow all tank-mix product labels for use rates and restrictions. Table 5: Zemax Tank Mixtures for Preemergence Applications in Corn Tank Mix 1 Objective AAtrex® or other solo atrazine products Improved broadleaf and grass weed control Gramoxone Inteon® Burndown existin g weeds Metribuzin 75DF or other metribuzin solo products Improved broadleaf weed control Princep® Improved broadleaf and grass weed control Touchdown® Brands Burndown existin g weeds Roundup® Brands Burndown existin g weeds 2,4-D Burndown existin g weeds Warrior II with Zeon Technology® To control insects, such as cutworm 1Refer to tank-mix product label for use rates. Early Postemergence (Applied After the Crop has Emerged) Tank-mix products listed in Table 6 may be used in conventional, reduced, or no-till systems and be applied by the same methods and at the same timings as Zemax unless otherwise specified in the tank-mix product label. Follow all tank-mix product labels for use rates and restrictions. Perform a compatibility test.

-23- Table 6: Zemax Tank Mixtures for Postemergence Applications in Field Corn Tank Mix1,2 Objective AAtrex or other solo atrazine products Improved broadleaf and annual grass weed control Accent® Q Emer ged grass control Basis® Emer ged grass control Ignite® See instructions under “Zemax Programs in LibertyLink® Corn” section of this label NorthStar® Improved broadleaf and grass weed control Peak® Improved broadleaf and grass weed control Resolve® Q Emer ged grass control Roundup Brands See instructions under “Zemax Programs in glyphosate tolerant Corn” section of this label Spirit® Improved broadleaf and grass weed control Status® Emer ged grass control Steadfast® Q Emer ged grass control Touchdown Brands See instructions under “Zemax Programs in glyphosate tolerant Corn” section of this label Warrior II with Zeon Technology To control insects, such as cutworm 1Refer to tank-mix product label for use rates. 2Consult the “Additives” section of this label for recommendations when applying Zemax in tank mixture to emerged field corn. Zemax Programs in Glyphosate Tolerant Corn Zemax may be applied early postemergence at a rate down to 1.6 qts./A in tank mixture with a solo glyphosate product (e.g. Touchdown or Roundup brands) that is registered for use over-the-top in glyphosate tolerant field corn (e.g. Roundup Ready or Agrisure® GT Corn). To minimize weed competition with the crop, target the application of this mixture to weeds in the 1 to 2 inch range. If the glyphosate product has a built-in adjuvant system (i.e. the product label does not ask for additional adjuvant), only spray- grade ammonium sulfate (AMS) at 8.5 lbs./100 gal. should be added to this mixture. If the glyphosate product label calls for an adjuvant in addition to AMS, add a non-ionic surfactant (NIS) at 0.25% v/v and AMS to this spray mixture. Do not add urea ammonium nitrate (UAN), crop oil concentrate (COC), or methylated seed oil (MSO) type adjuvants to these mixtures, or crop injury may occur. Follow all directions for use and restrictions on the glyphosate product label.

-24- Alternatively, Zemax may be applied preemergence at a rate down to 1.6 qts./A as part of a two-pass weed control system when followed by a postemergence application of a glyphosate based product in glyphosate tolerant corn (e.g. Roundup Ready or Agrisure GT Corn). When used in this way, Zemax will provide reduced competition of the weeds listed in Table 1 for a period of 30 or more days, thus improving the timing flexibility and effectiveness of the glyphosate based product application. Follow all directions for use and restrictions on the glyphosate product label. Zemax may be applied preemergence at 1.0-1.2 qts./A as part of a two-pass weed control system when followed by Halex™ GT in glyphosate tolerant corn (e.g. Roundup Ready or Agrisure GT Corn). Apply Zemax at 1.0 qt/A on soils with <3% OM and 1.2 qt/A on soils with >3% OM. Follow all directions for use and restrictions on each product label. Zemax Programs in LibertyLink Corn Zemax may be applied early postemergence at a rate down to 1.6 qts./A in tank mixture with Ignite and applied over-the-top in field corn designated as LibertyLink. To minimize weed competition with the crop, target the application of this mixture to weeds in the 1 to 2 inch range. Ammonium sulfate (AMS) may be added as a spray adjuvant as directed on the Ignite label. However, AMS should be the only adjuvant added to this tank mixture. Do not add urea ammonium nitrate (UAN), crop oil concentrate (COC), non-ionic surfactants (NIS), or methylated seed oil (MSO) type adjuvants to these mixtures, or crop injury may occur. Follow all directions for use and restrictions on the Ignite product label. Alternatively, Zemax may be applied preemergence at a rate down to 1.6 qts./A as part of a two-pass weed control system when followed by a postemergence application of Ignite in field corn designated as LibertyLink. When used in this way, Zemax will provide reduced competition of the weeds listed in Table 1 for a period of 30 or more days, thus improving the timing flexibility and effectiveness of the Ignite application. Follow all directions for use and restrictions on the Ignite product label. Restrictions and Precautions for all Corn Uses

1. Do not apply more than 2.4 quarts per acre per year (0.198 lb mesotrione ai/A and 2.10 lb s-metolachlor/A).
2. Do not exceed 3.71 lb ai/A/year of s-metolachlor containing products
3. Do not exceed 0.24 lb ai/A/year of mesotrione containing products
4. Do not apply Zemax to corn that is greater than 30 inches tall or corn that is larger than the 8-leaf stage of growth.

-25- 5. Do not graze or feed corn forage from treated areas for 45 days following postemergence application. 6. Do not harvest corn for forage, grain, or stover within 45 days after a postemergence application of Zemax. 7. Do not make postemergence applications of Zemax in a tank mix with any organophosphate or carbamate insecticide, or severe corn injury may occur. 8. Zemax applied postemergence to corn that has received an at-planting application of Counter® or other organophosphate insecticide can result in severe corn injury. Environmental conditions that favor poor or slow corn growth will increase the risk or severity of the corn injury. 9. Postemergence corn applications of any organophosphate or carbamate insecticide within 7 days before or 7 days after a Zemax application can result in severe corn injury. Environmental conditions that favor poor or slow corn growth will increase the risk or severity of the corn injury. GRAIN SORGHUM USE DIRECTIONS Zemax can be applied preplant nonincorporated (up to 21 days before planting) up through preemergence for weed control in sorghum that was seed-treated with a safener that provides tolerance to S-metolachlor (e.g. Concep® III). For a listing of weeds controlled or partially controlled, refer to Table 1. Apply Zemax at a rate of 2.0 qts./A as a broadcast nonincorporated spray beginning at 21 days before planting and up through planting but prior to sorghum emergence. Applying Zemax less than 7 days before sorghum planting will increase the risk of crop injury, especially if irrigation or rainfall is received following the application. Injury symptoms include temporary bleaching of newly emerging sorghum leaves or, in extreme conditions, stunting or partial stand loss. Applying Zemax more than 7 days (but not more than 21) prior to sorghum planting will reduce the risk of crop injury. If Zemax is applied prior to planting, minimize disturbance of the herbicide-treated soil barrier during the planting process in order to lessen the potential for poor weed control in the disturbed soil zone. Zemax may also be applied as a split application to grain sorghum. For a split application program, apply 1.0-1.25 qts./A of Zemax as a non-incorporated early preplant (7-21 days before planting), followed by a second Zemax application at a rate of 0.75-1.0 qts./A as a preemergence application prior to sorghum emergence. The total amount of Zemax applied in the split application program cannot exceed 2.0 qts./A. If weeds are present at the time of application, it is recommended that a nonionic surfactant (NIS) type adjuvant at a rate of 0.25% v/v or a crop oil concentrate (COC) at

-26- a rate of 1% v/v be added to the spray solution. In addition to COC or NIS, a spray grade UAN at a rate of 2.5% v/v or AMS at a rate of 8.5 lbs./100 gals. of spray may be added to the solution for improved control of emerged weeds. If weeds are not emerged at the time of application, no additives are recommended. Restrictions and Precautions for Grain Sorghum Uses

1. Do not apply more than 2.0 quarts per acre per year (1.75 s-metolachlor lb ai/A and 0.165 lb ai/A mesotrione)
2. Do not exceed 1.68 lb ai/A/year of s-metolachlor containing products
3. Do not exceed 0.2 lb ai/A/year of mesotrione containing products
4. Do not apply Zemax to sorghum grown on sandy soils (sand, sandy loam, or loamy sand).
5. Do not apply Zemax to emerged grain sorghum or severe injury will occur.
6. Do not use Zemax in the production of forage sorghum, sweet sorghum (sorgo), sudangrass, sorghum-sudangrass hybrids, or dual-purpose sorghum.
7. Sorghum seed must be treated with a seed safener that provides tolerance to S-metolachlor (e.g. Concep III) prior to planting, or severe crop injury may occur. STORAGE AND DISPOSAL Do not contaminate water, food, or feed by storage or disposal. Pesticide Storage Keep container tightly closed when not in use. Do not store near seeds, fertilizers, or food stuffs. Can be stored at temperatures as low as -10qF. Keep away from heat and flame. Pesticide Disposal Open dumping is prohibited. Waste resulting from the use of this product may be disposed of on site or at an approved waste disposal facility. Rinse spray equipment. Pesticide wastes are acutely hazardous. Improper disposal of excess pesticide, spray mixture, or rinsate is a violation of Federal law. If these wastes cannot be disposed of as described above, contact your State Pesticide or Environmental Control Agency, or the Hazardous Waste Representative at the nearest EPA Regional Office for guidance.

-27- Container Handling [less than or equal to 5 gallons] Non-refillable container. Do not reuse or refill this container.. Triple rinse container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank. Drain for 10 seconds after the flow begins to drip. Fill the container ¼ full with water and recap. Shake for 10 seconds. Pour rinsate into application equipment or a mix tank or store rinsate for later use and disposal. Drain for 10 seconds after the flow begins to drip. Repeat this procedure two more times. Then offer for recycling if available or puncture and dispose of in a sanitary landfill, or by incineration, or, if allowed by state and local authorities, by burning. If burned, stay out of smoke. Container Handling [greater than 5 gallon] Refillable container. Refill this container with pesticide only. Do not reuse this container for any other purpose. Cleaning the container before final disposal is the responsibility of the person disposing of the container. Cleaning before refilling is the responsibility of the person refilling. To clean container before final disposal, empty the remaining contents from this container into application equipment or mix tank. Fill the container about 10 percent full with water. Agitate vigorously or recirculate water with the pump for 2 minutes. Pour or pump rinsate into application equipment or rinsate collection system. Repeat this rinsing procedure two more times. Then offer for recycling if available or puncture and dispose of in a sanitary landfill, or by incineration, or by other procedures approved by state and local authorities. DO NOT USE CONTAINERS FOR THE STORAGE OF FOOD, FEED, OR DRINKING WATER! AAtrex®, Agrisure® GT, Concep® III, Gramoxone Inteon®, Halex™ GT, NorthStar®, Peak®, Princep®, Spirit®, Touchdown®, Warrior II with Zeon Technology®, Zemax®, the ALLIANCE FRAME, the SYNGENTA Logo and the PURPOSE ICON are Trademarks of a Syngenta Group Company Accent® Q, Basis®, Resolve® Q, Steadfast® Q and Viton® trademarks of E. I. du Pont de Nemours and Company Counter® and Status® trademarks of BASF Corporation Ignite® and LibertyLink® trademarks of Bayer CropScience Roundup® trademark of Monsanto Company ”20XX Syngenta

-28- For non-emergency information (e.g., current product information), call Syngenta Crop Protection at 1-800-334-9481 Manufactured for: Syngenta Crop Protection, LLC P. O. Box 18300 Greensboro, North Carolina 27419-8300 Zemax 1410 MAS 1111 AMEND-C JUN2021-CL.docx - kmj – 3/14/2022 000100-01410C.20210610.Zemax.AMEND.JUN2021-CL