crop-chem-docs/corpus/epa_ppls/100-1554.md

QUADRIS TOP SBX

• EPA Reg No: 100-1554
• Registrant: SYNGENTA CROP PROTECTION, LLC
• Signal word: Warning
• Active ingredients: Azoxystrobin (19.8%); Difenoconazole (19.8%)
• Label accepted: 2025-11-13
• Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000100-01554-20251113.pdf

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November 13, 2025 Ricky Kyaw Regulatory Product Manager Syngenta Crop Protection, LLC P. O. Box 18300 Greensboro, NC 27419 Subject: Label Amendment - Registration Review Mitigation for Azoxystrobin Product Name: QUADRIS TOP SBX EPA Registration Number: 100-1554 Case Number: 472197 Application Dates: 5/17/2019 Dear Ricky Kyaw: The Agency, in accordance with the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), as amended, has completed reviewing all the information submitted with your application to support the Registration Review of the above referenced product in connection with the Azoxystrobin Interim Decision, and has concluded that your submission is acceptable. The label referred to above, submitted in connection with registration under FIFRA, as amended, is acceptable. Should you wish to add/retain a reference to the company’s website on your label, then please be aware that the website becomes labeling under the Federal Insecticide, Fungicide, and Rodenticide Act and is subject to review by the Agency. If the website is false or misleading, the product would be misbranded and unlawful to sell or distribute under FIFRA section 12(a)(1)(E). 40 CFR 156.10(a)(5) list examples of statements EPA may consider false or misleading. In addition, regardless of whether a website is referenced on your product’s label, claims made on the website may not substantially differ from those claims approved through the registration process. Therefore, should the Agency find or if it is brought to our attention that a website contains false or misleading statements or claims substantially differing from the EPA approved registration, the website will be referred to the EPA’s Office of Enforcement and Compliance Assurance. A stamped copy of your labeling is enclosed for your records. This labeling supersedes all previously accepted labeling and must be used at your next label printing. You must submit one copy of the final printed labeling before you release the product for

Page 2 of 2 EPA Reg. No. 100-1554 Case No. 472197 shipment with the new labeling. In accordance with 40 CFR 152.130(c), you may distribute or sell this product under the previously approved labeling for 12 months from the date of this letter. After 12 months, you may only distribute or sell this product if it bears this new revised labeling or subsequently approved labeling. “To distribute or sell” is defined under FIFRA section 2(gg) and its implementing regulation at 40 CFR 152.3. If you have any questions about this letter, please contact Carolyn Smith by phone at 202-566- 2273, or via email at smith.carolyn@epa.gov. Sincerely, Jaclyn Pyne, Team Leader Risk Management and Implementation Branch 3 Pesticide Re-Evaluation Division Office of Pesticide Programs ENCLOSURE: Stamped label

Quadris Top SBX Fungicide Page 1 AZOXYSTROBIN GROUP 11 FUNGICIDE DIFENOCONAZOLE GROUP 3 FUNGICIDE Quadris Top® SBX Fungicide Active Ingredients: Azoxystrobin* .......................................................................................................... 19.8% Difenoconazole** ..................................................................................................... 19.8% Other Ingredients: 60.4% Total: 100.0% *CAS No. 131860-33-8 **CAS No. 119446-68-3 Quadris Top SBX is formulated as a suspension concentrate (SC) containing 1.88 lb of azoxystrobin active ingredient and 1.88 lb of difenoconazole active ingredient per gallon. KEEP OUT OF REACH OF CHILDREN. WARNING/AVISO Si usted no entiende la etiqueta, busque a alguien para que se la explique a usted en detalle. (If you do not understand the label, find someone to explain it to you in detail.) See additional precautionary statements and directions for use inside booklet. See First Aid statement inside booklet or on container label. EPA Reg. No. 100-1554 EPA Est. _____ gallons Net Contents 11/13/2025 100-1554

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FIRST AID If swallowed

• Call a poison control center or doctor immediately for treatment advice. • Have person sip a glass of water if able to swallow. • Do not induce vomiting unless told to by a poison control center or doctor. • Do not give anything by mouth to an unconscious person. Have the product container or label with you when calling a poison control center or doctor, or going for treatment. HOT LINE NUMBER For 24-Hour Medical Emergency Assistance (Human or Animal) Or Chemical Emergency Assistance (Spill, Leak, Fire or Accident) Call 1-800-888-8372

PRECAUTIONARY STATEMENTS

Hazards to Humans and Domestic Animals

WARNING/AVISO

May be fatal if swallowed. Wash thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco, or using the toilet.

Personal Protective Equipment (PPE)

Applicators and other handlers must wear:

• Long-sleeved shirt and long pants • Shoes plus socks • Waterproof gloves

Discard clothing and other absorbent materials that have been drenched or heavily contaminated with this product’s concentrate. DO NOT reuse them.

User Safety Requirements

Follow manufacturer’s instructions for cleaning/maintaining PPE. If no such instructions for washables exist, use detergent and hot water. Keep and wash PPE separately from other laundry.

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Engineering Controls

When handlers use closed systems, enclosed cabs, or aircraft in a manner that meets the requirements listed in the Worker Protection Standard (WPS) for agricultural pesticides [40 CFR 170.240(d)(4-6)], the handler PPE requirements may be reduced or modified as specified in the WPS. Human flagging is prohibited.

User Safety Recommendations

Users should:

• Wash hands before eating, drinking, chewing gum, using tobacco, or using the toilet. • Remove clothing/PPE immediately if pesticide gets inside. Then wash thoroughly and put on clean clothing. • Remove PPE immediately after handling this product. Wash the outside of gloves before removing. As soon as possible, wash thoroughly and change into clean clothing.

Environmental Hazards

Difenoconazole is toxic to fish, mammals and aquatic invertebrates. Drift and runoff may be hazardous to estuarine/marine organisms in water adjacent to treated areas.

Azoxystrobin is toxic to freshwater and estuarine/marine fish and aquatic invertebrates. Azoxystrobin can be persistent for several months or longer.

Do not discharge effluent containing this product into lakes, streams, ponds, estuaries, oceans or other waters unless in accordance with the requirements of a National Pollutant Discharge Elimination System (NPDES) permit and the permitting authority has been notified in writing prior to discharge. Do not discharge effluent containing this product to sewer systems without previously notifying the local sewage treatment plant authority. For guidance, contact your State Water Board or regional office of the EPA.

For terrestrial uses: Do not apply directly to water, or to areas where surface water is present or to intertidal areas below the mean high water mark. Drift and runoff may be hazardous to aquatic organisms in water adjacent to treated areas. Do not contaminate water when disposing of equipment washwater or rinsate.

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Groundwater Advisory

Azoxystrobin and a degradate of azoxystrobin are known to leach through soil into groundwater under certain conditions as a result of label use. This chemical may leach into groundwater if used in areas where soils are permeable, particularly where the water table is shallow.

Surface Water Advisory

This product may impact surface water quality due to runoff of rain water. This is especially true for poorly draining soils and soils with shallow ground water. This product is classified as having a high potential for reaching surface water via runoff for several months or more after application. A level, well-maintained vegetative buffer strip between areas to which this product is applied and surface water features such as ponds, streams, and springs will reduce the potential loading of Azoxystrobin and a degradate of Azoxystrobin from runoff water and sediment. Runoff of this product will be reduced by avoiding applications when rainfall or irrigation is expected to occur within 48 hours.

Notify State and/or Federal authorities and Syngenta immediately if you observe any adverse environmental effects due to use of this product.

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CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY

NOTICE: Read the entire Directions for Use and Conditions of Sale and Limitation of Warranty and Liability before buying or using this product. If the terms are not acceptable, return the product at once, unopened, and the purchase price will be refunded.

The Directions for Use of this product must be followed carefully. It is impossible to eliminate all risks inherently associated with the use of this product. Crop injury, ineffectiveness or other unintended consequences may result because of such factors as manner of use or application, weather or crop conditions, presence of other materials or other influencing factors in the use of the product, which are beyond the control of SYNGENTA CROP PROTECTION, LLC or Seller. To the extent permitted by applicable law, Buyer and User agree to hold SYNGENTA and Seller harmless for any claims relating to such factors.

SYNGENTA warrants that this product conforms to the chemical description on the label and is reasonably fit for the purposes stated in the Directions for Use, subject to the inherent risks referred to above, when used in accordance with directions under normal use conditions. To the extent permitted by applicable law: (1) this warranty does not extend to the use of this product contrary to label instructions, or under conditions not reasonably foreseeable to or beyond the control of Seller or SYNGENTA, and, (2) Buyer and User assume the risk of any such use. TO THE EXTENT PERMITTED BY APPLICABLE LAW, SYNGENTA MAKES NO WARRANTIES OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE NOR ANY OTHER EXPRESS OR IMPLIED WARRANTY EXCEPT AS WARRANTED BY THIS LABEL.

To the extent permitted by applicable law, in no event shall SYNGENTA be liable for any incidental, consequential or special damages resulting from the use or handling of this product. TO THE EXTENT PERMITTED BY APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE USER OR BUYER, AND THE EXCLUSIVE LIABILITY OF SYNGENTA AND SELLER FOR ANY AND ALL CLAIMS, LOSSES, INJURIES OR DAMAGES (INCLUDING CLAIMS BASED ON BREACH OF WARRANTY, CONTRACT, NEGLIGENCE, TORT, STRICT LIABILITY OR OTHERWISE) RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, SHALL BE THE RETURN OF THE PURCHASE PRICE OF THE PRODUCT OR, AT THE ELECTION OF SYNGENTA OR SELLER, THE REPLACEMENT OF THE PRODUCT.

SYNGENTA and Seller offer this product, and Buyer and User accept it, subject to the foregoing Conditions of Sale and Limitation of Warranty and Liability, which may not be modified except by written agreement signed by a duly authorized representative of SYNGENTA.

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DIRECTIONS FOR USE

It is a violation of Federal Law to use this product in a manner inconsistent with its labeling.

Do not apply this product in a way that will contact workers or other persons, either directly or through drift. Only protected handlers may be in the area during application. For any requirements specific to your State or Tribe, consult the agency responsible for pesticide regulation.

AGRICULTURAL USE REQUIREMENTS

Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR Part 170. This Standard contains requirements for the protection of agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of agricultural pesticides. It contains requirements for training, decontamination, notification, and emergency assistance. It also contains specific instructions and exceptions pertaining to the statements on this label about personal protective equipment (PPE) and restricted-entry interval. The requirements in this box only apply to uses of this product that are covered by the Worker Protection Standard.

Do not enter or allow worker entry into treated areas during the restricted-entry interval (REI) of 12 hours.

PPE required for early entry to treated areas that is permitted under the Worker Protection Standard and that involves contact with anything that has been treated, such as plants, soil, or water is:

• Coveralls • Chemical-resistant gloves made of any waterproof material. • Shoes plus socks

PRODUCT INFORMATION

Quadris Top SBX is a broad-spectrum product containing two fungicides. It has preventative, systemic and curative properties and is recommended for the control of many important plant diseases. Quadris Top SBX provides excellent disease control of many leaf spots and powdery mildews. Quadris Top SBX is applied as a foliar spray and can be used in block, alternating spray or tank-mix programs with other crop protection products. All applications must be made according to the use directions that follow.

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USE PRECAUTIONS AND RESTRICTIONS

FAILURE TO FOLLOW DIRECTIONS AND PRECAUTIONS ON THIS LABEL MAY RESULT IN CROP INJURY, POOR DISEASE CONTROL, AND/OR ILLEGAL RESIDUES.

PHYTOTOXICITY ATTENTION

Quadris Top SBX is extremely phytotoxic to certain apple varieties.

AVOID SPRAY DRIFT. Extreme care must be used to prevent injury to apple trees (and apple fruit).

DO NOT spray Quadris Top SBX where spray drift may reach apple trees.

DO NOT use spray equipment which has been previously used to apply Quadris Top SBX to spray apple trees. Even trace amounts can cause unacceptable phytotoxicity to certain apple and crabapple varieties.

AVOIDING SPRAY DRIFT IS THE RESPONSIBILITY OF THE APPLICATOR.

USE INFORMATION

Application: Thorough coverage is necessary to provide good disease control. Make no more spray solution than is needed for application. Avoid spray overlap, as crop injury may occur.

Adjuvants: When an adjuvant is to be used with this product, the use of an adjuvant that meets the standards of the Chemical Producers and Distributors Association (CPDA) adjuvant certification program is recommended.

Use of Adjuvants: Under certain weather conditions (particularly high temperatures) Quadris Top SBX in combination with high rates of silicone-based or oil containing (petroleum or crop) additives or adjuvants may cause injury. Do not exceed 0.125% adjuvant (v/v). Consult a Syngenta representative for more information concerning additives or adjuvants.

A tank mixture with Dimethoate may cause crop injury.

On fresh market tomatoes, do not use adjuvants or tank mix Quadris Top SBX with any EC product.

Efficacy: Under certain conditions conducive to extended infection periods, use another registered fungicide for additional applications if the maximum amount of Quadris Top SBX has been used. If resistant isolates to Group 3 or Group 11

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fungicides are present, efficacy can be reduced for certain diseases. The higher rates in the rate range and/or shorter spray intervals may be required under conditions of heavy infection pressure, with highly susceptible varieties, or when environmental conditions are conducive to disease.

Integrated Pest Management (IPM): Quadris Top SBX should be integrated into an overall disease and pest management strategy whenever the use of a fungicide is required. Cultural practices known to reduce disease development should be followed. Consult your local agricultural authorities for additional IPM strategies established for your area. Quadris Top SBX may be used in State Agricultural Extension advisory (disease forecasting) programs which recommend application timing based on environmental factors favorable for disease development.

Resistance Management

AZOXYSTROBIN GROUP 11 FUNGICIDE DIFENOCONAZOLE GROUP 3 FUNGICIDE

For resistance management, please note that Quadris Top SBX contains both azoxystrobin, a strobilurin fungicide in Group 11 and difenoconazole, a triazole fungicide in Group 3. Any fungal population may contain individuals naturally resistant to either or both of the active ingredients in Quadris Top SBX and other Group 11 or Group 3 fungicides. A gradual or total loss of pest control may occur over time if these fungicides are used repeatedly in the same fields. Appropriate resistance-management strategies should be followed.

As part of a resistance management strategy:

• Apply a maximum of 4 sprays during one crop cycle. • Apply no more than 2 sequential applications unless otherwise stated in the crop section. • Rotate the use of Quadris Top SBX or other Group 3 and 11 fungicides within a growing season sequence with different groups that control the same pathogens. • Use tank mixtures with fungicides from a different group that are equally effective on the target pest when such use is permitted. Use at least the minimum application rate as labeled by the manufacturer. • Adopt an integrated disease management program for fungicide use that includes scouting, uses historical information related to pesticide use, and crop rotation, and which considers host plant resistance, impact of environmental conditions on disease development, disease thresholds, as well as cultural, biological and other chemical control practices. • Where possible, make use of predictive disease models to effectively time fungicide applications. Note that using predictive models alone is not sufficient to manage resistance. • Monitor treated fungal populations for resistance development. • Contact your local extension specialist or certified crop advisor for any additional

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pesticide resistance-management and/or IPM recommendations for specific crops and pathogens. • For further information or to report suspected resistance contact Syngenta Crop Protection at 1-866-796-4368. You can also contact your pesticide distributor or university extension specialist to report resistance.

Rotational Crops: Please see the following table for the crop rotational restrictions:

Rotational Crops Planting Time From Last Quadris Top SB X Application Berry, Low Growing, Subgroup 13-07G, Brassica (Cole) Leafy Vegetables Crop Group 5 Bulb Vegetables, bulb onion Subgroup 3-07A and green onion Subgroup 3-07B Carrots Chickpeas Citrus Fruit Crop Group 10-10 Cotton Subgroup 20C Cucurbit Vegetables Crop Group 9 Fruit, small, vine climbing Subgroup 13-07F, except fuzzy kiwifruit Fruiting Vegetables Crop Group 8-10 Guava Papaya Okra Pepper Potatoes Rice Soybeans Stone Fruit Crop Group 12-12 Strawberries Sugar Beets Tomatoes Tree Nuts Crop Group 14-12 Tuberous & Corm Vegetable Subgroup 1C Watercress Wild Rice 0 days Cereals (Wheat, Barley, Oats, Rye, Triticale) Root and Tuber Vegetables, Crop Group 1 (except Carrot, Sugar Beet, and Tuberous Corm Vegetable Sub group 1C) 30 days Buckwheat Millet 365 days All Other Crops Intended for Food and Feed 60 da ys

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Crop Tolerance: Plant tolerance has been found to be acceptable for all crops on the label, however, not all possible tank-mix combinations have been tested under all conditions. When possible, it is recommended to test the combinations on a small portion of the crop to ensure that a phytotoxic response will not occur as a result of application. See USE PRECAUTIONS AND RESTRICTIONS regarding apple phytotoxicity.

Greenhouse Use: For resistance management, do not use Quadris Top SBX for transplant production.

SPRAY DRIFT MANAGEMENT

To avoid spray drift, do not apply when conditions favor drift beyond the target area. The interaction of many equipment and weather related factors determine the potential for spray drift. AVOIDING SPRAY DRIFT AT THE APPLICATION SITE IS THE RESPONSIBILITY OF THE APPLICATOR AND THE GROWER.

SPRAY DRIFT MANAGEMENT

Aerial Applications

• Do not release spray at a height greater than 10 ft. above the crop canopy, unless a greater application height is necessary for pilot safety. • Applicators are required to select nozzles that deliver medium to coarse spray droplets in accordance with ASABE Standard S-641. • Do not apply when wind speeds exceed 15 mph at the application site. If the windspeed is greater than 10 mph, the boom length must be 65% or less of the wingspan for fixed wing aircraft and 75% or less of the rotor diameter for helicopters. Otherwise, the boom length must be 75% or less of the wingspan for fixed-wing aircraft and 90% or less of the rotor diameter for helicopters. • Applicators must use ½ swath displacement upwind at the downwind edge of the field. • Do not apply during temperature inversions.

Ground Boom Applications

• User must only apply with the release height recommended by the manufacturer, but no more than 4 feet above the ground or crop canopy. • Applicators are required to use a medium or coarser droplet size (ASABE S-572.1). • Do not apply when wind speeds exceed 15 miles per hour at the application site. • Do not apply during temperature inversions.

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SPRAY DRIFT ADVISORIES

• THE APPLICATOR IS RESPONSIBLE FOR AVOIDING OFF-SITE SPRAY DRIFT. • BE AWARE OF NEARBY NON-TARGET SITES AND ENVIRONMENTAL CONDITIONS.

IMPORTANCE OF DROPLET SIZE The effective way to reduce spray drift is to apply large droplets. Use the largest droplets that provide target pest control. While applying larger droplets will reduce spray drift, the potential for drift will be greater if applications are made improperly or under unfavorable environmental conditions.

Controlling Droplet Size – Groundboom • Volume - Increasing the spray volume so that larger droplets are produced will reduce spray drift. Use the highest practical spray volume for the application. If a greater spray volume is needed, consider using a nozzle with higher flow rate. • Pressure - Use the lowest spray pressure recommended for the nozzle to produce the target spray volume and droplet size. • Nozzle Type - Use a spray nozzle that is designed for the intended application. Consider using nozzles designed to reduce drift.

Controlling Droplet Size – Aircraft • Adjust Nozzles - Follow nozzle manufacturers recommendations for setting up nozzles. Generally, to reduce fine droplets, nozzles should be oriented parallel with the airflow in flight.

BOOM HEIGHT – Groundboom • For ground equipment, the boom should remain level with the crop and have minimal bounce.

RELEASE HEIGHT – Aircraft • Higher release heights increase the potential for spray drift.

SHIELDED SPRAYERS • Shielding the boom or individual nozzles can reduce spray drift. Consider using shielded sprayers. Verify that the shields are not interfering with the uniform deposition of the spray on the target area.

TEMPERATURE AND HUMIDITY • When making applications in hot and dry conditions, set up equipment to produce larger droplets to reduce effects of evaporation.

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TEMPERATURE INVERSIONS • Drift potential is high during a temperature inversion. Temperature inversions are characterized by increasing temperature with altitude and are common on nights with limited cloud cover and light to no wind. Their presence of an inversion can be indicated by ground fog or by the movement of smoke from a ground source or an aircraft smoke generator. Smoke that layers and moves laterally in a concentrated cloud (under low wind conditions) indicates an inversion, while smoke that moves upward and rapidly dissipates indicates good vertical air mixing. Avoid applications during temperature inversions. WIND • Drift potential increases at wind speeds. AVOID APPLICATIONS DURING GUSTY WIND CONDITIONS. • Applicator need to be familiar with local wind patterns and terrain that could affect spray drift.

MIXING AND APPLICATION METHODS

Spray Equipment

Nozzles

• Equip sprayers with nozzles that provide accurate and uniform application. • Nozzles should be the same size and uniformly spaced across the boom. • Calibrate sprayer before use. • It is suggested that screens be used to protect the pump and to prevent nozzles from clogging. • Screens placed on suction side of pump should be 16-mesh or coarser. • Do not place a screen in the recirculation line. • Use 50-mesh or coarser screens between the pump and boom, and where required, at the nozzles. • Check nozzle manufacturer’s recommendations.

Pump

• Use a pump with capacity to: (1) Maintain 35-40 psi at nozzles. (2) Provide sufficient agitation in tank to keep mixture in suspension - this requires recirculation of 10% of tank volume per minute. • Use a jet agitator or liquid sparge tube for agitation. • Do not air sparge.

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For more information on spray equipment and calibration, consult sprayer manufacturer’s and state recommendations. For specific local directions and spray schedules, consult the current state agricultural recommendations.

Mixing Instructions

• Quadris Top SBX is a suspension concentrate (SC) formulation. • Prepare no more spray mixture than is required for the immediate operation. • Thoroughly clean spray equipment before using this product. • Agitate the spray solution before and during application. • Rinse spray tank thoroughly with clean water after each day’s use and dispose of pesticide rinsate by application to an already treated area.

Quadris Top SBX Alone (No Tank Mix)

• Add ½- Ҁ of the required amount of water to the spray or mixing tank. • With the agitator running, add Quadris Top SBX to the tank. • Continue agitation while adding the remainder of the water. • Begin application of the spray solution after Quadris Top SBX has completely dispersed into the mix water. • Maintain agitation until all of the mixture has been sprayed.

Quadris Top SBX + Tank Mixtures: Quadris Top SBX is usually compatible with all tank-mix partners listed on this label. To determine the physical compatibility of Quadris Top SBX with other products, use a jar test. Using a quart jar, add the proportionate amounts of the products to 1 qt of water. Add wettable powders and water dispersible granular products first, then liquid flowables, and emulsifiable concentrates last. After thoroughly mixing, let stand for at least 5 minutes. If the combination remains mixed or can be remixed readily, it is physically compatible. Once compatibility has been proven, use the same procedure for adding required ingredients to the spray tank.

It is the pesticide user’s responsibility to ensure that all products are registered for the intended use. Read and follow the applicable restrictions and limitations and directions for use on all product labels involved in tank mixing. Users must follow the most restrictive directions for use and precautionary statements of each product in the tank mixture.

Mixing in the Spray Tank

• Add ½- Ҁ of the required amount of water to the spray or mixing tank. • With the agitator running, add the tank-mix partner(s) into the tank in the same order as described above. • Allow the material to completely dissolve and disperse into the mix water. Continue agitation while adding the remainder of the water and Quadris Top SBX to the spray tank. • Allow Quadris Top SBX to completely disperse.

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• Spray the mixture with the agitator running. • Observe all directions for use, crops/sites, use rates, dilution ratios, precautions, and limitations which appear on the tank mix product label. • Label dosage rate must not be exceeded, and the most restrictive label precautions and limitations must be followed. • This product must not be mixed with any product which prohibits such mixing. • It is the pesticide user’s responsibility to ensure that all products are registered for the intended use. Read and follow the applicable restrictions and limitations and directions for use on all product labels involved in tank mixing. Users must follow the most restrictive directions for use and precautionary statements of each product in the tank mixture.

Application Instructions

Quadris Top SBX may be applied with all types of spray equipment commonly used for making ground and aerial applications. Proper adjustments and calibration of spraying equipment to give good canopy penetration and coverage is essential for good disease control.

Ground Application

• Apply in a minimum of 10 gal of water per acre, unless specified otherwise. • Do not apply through any ultra-low volume (ULV) spray system. • Thorough coverage is necessary to provide good disease control.

Aerial Application

• Use only on crops where aerial applications are indicated. • Thorough coverage is necessary to provide good disease control. • Apply in a minimum of 5 gallons of water per acre unless specified otherwise. • Avoid application under conditions when uniform coverage cannot be obtained or when excessive spray drift may occur. • Do not apply directly to humans or animals. • Do not apply through any ultra-low volume (ULV) spray system.

Application Through Irrigation Systems (Chemigation)

• Use only on crops for which chemigation is specified on this label. • Apply this product only through center pivot, solid set, hand move, or moving wheel irrigation systems. Do not apply this product through any other type of irrigation system. • Crop injury, lack of effectiveness, or illegal pesticide residues in the crop can result from non-uniform distribution of treated water. • Apply in 0.1-0.25 inches/acre. Excessive water may reduce efficacy.

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• If you have questions about calibration, you should contact State Extension Service specialists, equipment manufacturers, or other experts. • Do not connect an irrigation system (including greenhouse systems) used for pesticide application to a public water system, unless the pesticide label-prescribed safety devices for public water systems are in place. • A person knowledgeable of the chemigation system and responsible for its operation, or under the supervision of the responsible person, shall shut the system down and make necessary adjustments should the need arise.

Operating Instructions

1. The system must contain a functional check-valve, vacuum relief valve, and low pressure drain appropriately located on the irrigation pipeline to prevent water- source contamination from backflow.

2. The pesticide injection pipeline must contain a functional, automatic, quick- closing check-valve to prevent the flow of fluid back toward the injection pump.

3. The pesticide injection pipeline must also contain a functional, normally closed, solenoid-operated valve located on the intake side of the injection pump and connected to the system interlock to prevent fluid from being withdrawn from the supply tank when the irrigation system is either automatically or manually shut down.

4. The system must contain functional interlocking controls to automatically shut off the pesticide injection pump when the water pump motor stops.

5. The irrigation line or water pump must include a functional pressure switch which will stop the water pump motor when the water pressure decreases to the point where pesticide distribution is adversely affected.

6. Systems must use a metering pump, such as a positive displacement injection pump (e.g., diaphragm pump), effectively designed and constructed of materials that are compatible with pesticides and capable of being fitted with a system interlock.

7. Do not apply when wind speed favors drift beyond the area intended for treatment.

Center Pivot Irrigation Equipment

Notes: (1) Use only with drive systems which provide uniform water distribution. (2) Do not use end guns when chemigating Quadris Top SBX through center pivot systems because of non-uniform application.

• Determine the size of the area to be treated.

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• Determine the time required to apply ǩ-½ inch of water over the area to be treated when the system and injection equipment are operated at normal pressures as recommended by the equipment manufacturer. When applying Quadris Top SBX through irrigation equipment use the lowest obtainable water volume while maintaining uniform distribution. Run the system at 80-95% of the manufacturer’s rated capacity. • Using water, determine the injection pump output when operated at normal line pressure. • Determine the amount of Quadris Top SBX required to treat the area covered by the irrigation system. • Add the required amount of Quadris Top SBX and sufficient water to meet the injection time requirements to the solution tank. • Make sure the system is fully charged with water before starting injection of the Quadris Top SBX solution. Time the injection to last at least as long as it takes to bring the system to full pressure. • Maintain constant solution tank agitation during the injection period. • Continue to operate the system until the Quadris Top SBX solution has cleared the sprinkler head.

Solid Set, Hand Move, and Moving Wheel Irrigation Equipment

• Determine the acreage covered by the sprinklers. • Fill injector solution tank with water and adjust flow rate to use the contents over a 20- to 30-minute interval. When applying Quadris Top SBX through irrigation equipment use the lowest obtainable water volume while maintaining uniform distribution. • Determine the amount of Quadris Top SBX required to treat the area covered by the irrigation system. • Add the required amount of Quadris Top SBX into the same quantity of water used to calibrate the injection period. • Operate the system at the same pressure and time interval established during the calibration. • Stop injection equipment after treatment is completed. Continue to operate the system until the Quadris Top SBX solution has cleared the last sprinkler head.

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SPECIFIC INSTRUCTIONS FOR PUBLIC WATER SYSTEMS

1. Public water system means a system for the provision to the public of piped water for human consumption if such system has at least 15 service connections or regularly serves an average of at least 25 individuals daily at least 60 days out of the year.

2. Chemigation systems connected to public water systems must contain a functional, reduced-pressure zone, back-flow preventer (RPZ) or the functional equivalent in the water supply line upstream from the point of pesticide introduction. As an option to the RPZ, the water from the public water system should be discharged into a reservoir tank prior to pesticide introduction. There shall be a complete physical break (air gap) between the outlet end of the fill pipe and the top or overflow rim of the reservoir tank of at least twice the inside diameter of the fill pipe.

3. The pesticide injection pipeline must contain a functional, automatic, quick- closing check valve to prevent the flow of fluid back toward the injection pump.

4. The pesticide injection pipeline must contain a functional, normally closed, solenoid-operated valve located on the intake side of the injection pump and connected to the system interlock to prevent fluid from being withdrawn from the supply tank when the irrigation system is either automatically or manually shut down.

5. The system must contain functional interlocking controls to automatically shut off the pesticide injection pump when the water pump motor stops, or in cases where there is no water pump, when the water pressure decreases to the point where pesticide distribution is adversely affected.

6. Systems must use a metering pump, such as a positive displacement injection pump (e.g., diaphragm pump) effectively designed and constructed of materials that are compatible with pesticides and capable of being fitted with a system interlock.

7. Do not apply when wind speed favors drift beyond the area intended for treatment.

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SPECIFIC DIRECTIONS FOR USE

Crop

Target Diseases Use Rate fl oz product/A Remarks Almonds

Alternaria Leaf Spot (A. alternata)

Anthracnose (Colletotrichum acutatum)

Blossom Blight (Monilinia spp.)

Leaf Blight (Seimatosporium lichenicola)

Leaf Rust (Tranzschelia discolor)

Scab (Venturia carpophilia)

Shot Hole (Wilsonomyces carpophilus)

7.0-7.5

For blossom blight, begin applications at early bloom and continue through petal fall. Make no more than 2 sequential applications before alternating to another fungicide with a different mode of action.

For all other diseases, begin applications prior to disease onset when conditions are conducive for disease. Apply Quadris Top SBX on a 14- to 21- day schedule making no more than 2 sequential applications before alternating to another fungicide with a non-QoI (Group 11) mode of action.

If monitoring or history indicates the presence of Alternaria, apply 14 fl oz/A of Quadris Top SBX in the late spring (mid-April to beginning of May) and then repeat the treatment 2-3 weeks later.

The addition of a spreading/penetrating type adjuvant such as a non-ionic based surfactant or crop oil concentrate or blend is recommended.

[Optional language if label has a rate range: If disease pressure is high, use the highest rate.]

[Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval.]

[Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and hi ghest rate.] Application: For best results, sufficient water volume must be used to provide thorough coverage. Quadris Top SBX can be applied by ground or aerial application. Use a minimum of 15 gal/A for ground applications. For aerial applications, use a minimum of 10 gal/A of water. Specific Use Restrictions:

1. Do not apply more than 31 fl oz/A/year of Quadris Top SBX.
2. Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
3. Do not apply more than 1.5 lb ai/A/year of azoxystrobin-containing products.
4. Do not appl y within 28 days of harvest (28-day PHI).

Quadris Top SBX Fungicide Page 19

Crop

Target Diseases Use Rate fl oz product/A Remarks Berry, Low Growing, Subgroup 13-07G

Strawberry

Including all cultivars and/or hybrids of these

See complete list of low growing berries below.

See separate instructions for cranberry.

Anthracnose (Colletotrichum spp.)

Leaf Rust (Phragmidium potentillae)

Leaf Spot (Cercospora fragariae)

Powdery Mildew (Sphaerotheca macularis)

7.0-7.5

Begin applications prior to disease onset when conditions are conducive for disease. Apply Quadris Top SBX on a 7- to 14-day schedule making no more than 2 sequential applications before alternating to another fungicide with a different mode of action.

The addition of a spreading/penetrating type adjuvant such as a non-ionic based surfactant or crop oil concentrate or blend is recommended.

[Optional language if label has a rate range: If disease pressure is high, use the highest rate.]

[Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval.]

[Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and hi ghest rate.] Application: For best results, sufficient water volume must be used to provide thorough coverage. Quadris Top SBX can be applied by ground, chemigation, or aerial application. Use a minimum of 15 gal/A for ground applications. For aerial applications, use a minimum of 10 gal/A of water. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water ma y lead to a decrease in efficacy. Complete List of Additional Low Growing Berries: Bearberry; Bilberry; Blueberry, lowbush; Cloudberry; Lingonberry; Muntries; Partridgeberry; Strawberry; cultivars, varieties, and/or hybrids of these. Specific Use Restrictions:

1. Do not apply more than 31 fl oz/A/year of Quadris Top SBX.
2. Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
3. Do not apply more than 1.0 lb ai/A/year of azoxystrobin-containing products.
4. Quadris Top SBX ma y be applied up to 0 day of harvest (0-day PHI).

Quadris Top SBX Fungicide Page 20

Crop

Target Diseases Use Rate fl oz product/A Remarks Brassica (Cole) Leafy Vegetables Crop Group 5

Broccoli Brussels Sprouts Cabbage Cauliflower Collards Kale Mustard Greens

Including all cultivars and/or hybrids of these

See additional crops below.

Alternaria Diseases ( Alternaria spp.)

Anthracnose ( Colletotrichum higginsianum)

Cercospora Leaf Spot ( C. brassicicola)

Powdery Mildew ( Erysiphe polygoni)

7.0-7.5

Begin applications prior to disease onset when conditions are conducive for disease. Apply Quadris Top SBX on a 7- to 14-day schedule, making no more than 1 application before alternating to another fungicide with a non-QoI (Group 11) mode of action.

The addition of a spreading/penetrating type adjuvant such as a non-ionic based surfactant or crop oil concentrate or blend is recommended.

[Optional language if label has a rate range: If disease pressure is high, use the highest rate.]

[Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval.]

[Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and hi ghest rate.] Application: For best results, sufficient water volume must be used to provide thorough coverage. Quadris Top SBX can be applied by ground, chemigation, or aerial application. Use a minimum of 15 gal/A for ground applications. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy. Complete List of Brassica Leafy Vegetables: Broccoli; broccoli, Chinese (gai lon); broccoli raab (rapini); Brussels sprouts; cabbage; cabbage, Chinese (bok choy); cabbage, Chinese (napa); cabbage, Chinese mustard(gai choy); cauliflower; cavalo broccolo; collards; kale; kohlrabi; mizuna; mustard greens; mustard spinach; rape greens; turnip greens Specific Use Restrictions:

1. Do not apply more than 31 fl oz/A/year of Quadris Top SBX.
2. Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
3. Do not apply more than 0.75 lb ai/A/year of azoxystrobin-containing products.
4. Do not apply within 1 day of harvest (1-day PHI).

Quadris Top SBX Fungicide Page 21

Crop

Target Diseases Use Rate fl oz product/A Remarks Bulb Vegetables

Onion, Bulb Subgroup 3- 07A Garlic Shallot

Onion, Green Subgroup 3-07B Leek Welsh Onion

Botrytis Leaf Blight ( B. squamosa)

Cercospora Leaf Spot ( C. duddiae)

Leaf Blotch ( Cladosporium allii- cepae)

Powdery Mildew ( Leveillula taurica)

Purple Blotch ( Alternaria porri)

Stemphyllium Leaf Blight ( S. vesicarium)

7.0-7.5

Begin applications prior to disease onset when conditions are conducive for disease. Apply Quadris Top SBX on a 7- to 14-day schedule, making no more than 1 application before alternating to another fungicide with a non-QoI (Group 11) mode of action.

The addition of a spreading/penetrating type adjuvant such as a non-ionic based surfactant or crop oil concentrate or blend is recommended.

[Optional language if label has a rate range: If disease pressure is high, use the highest rate.]

[Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval.]

[Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and hi ghest rate.] Application: For best results, sufficient water volume must be used to provide thorough coverage. Quadris Top SBX can be applied by ground, chemigation, or aerial application. Use a minimum of 15 gal/A for ground applications. For chemi gation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy. Complete List of Bulb Vegetables: Chive, fresh leaves; chive, Chinese, fresh leaves; daylily, bulb; elegans hosta; fritillaria, bulb; fritillaria, leaves; garlic, bulb; garlic, great-headed, bulb; garlic, serpent, bulb; kurrat; lady’s leek; leek; leek, wild; lily, bulb; onion, Beltsville bunching; onion, bulb; onion, Chinese, bulb; onion, fresh; onion, green; onion, macrostem; onion, pearl; onion, potato, bulb; onion, tree, tops; onion, Welsh, tops; shallot, bulb; shallot, fresh leaves; cultivars, varieties, and/or hybrids of these. Specific Use Restrictions:

1. For green onions, do not apply more than 23 fl oz/A/year of Quadris Top SBX.
2. For green onions, do not apply more than 0.34 lb ai /A/year of difenoconazole-containing products.
3. For dry bulb onions, do not apply more than 31 fl oz/A/year of Quadris Top SBX.
4. For dry bulb onions, do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
5. For the bulb crop group, do not apply more than 1.5 lb ai/A/year of azoxystrobin-containing products. 6 ) Do not appl y within 7 days of harvest (7-day PHI).

Quadris Top SBX Fungicide Page 22

Crop

Target Diseases Use Rate fl oz product/A Remarks Carrots Alternaria Leaf Blight ( Alternaria dauci)

Cercospora Leaf Spot ( Cercospora carotae)

Powdery Mildew ( Erysiphe spp.)

Southern Blight ( Sclerotium rolfsii) 7.0-7.5

Begin applications prior to disease onset when conditions are conducive for disease. Apply Quadris Top SBX on a 7- to 10-day schedule making no more than 2 sequential applications before alternating to another fungicide with a different mode of action.

The addition of a spreading/penetrating type adjuvant such as a non-ionic based surfactant or crop oil concentrate or blend is recommended.

[Optional language if label has a rate range: If disease pressure is high, use the highest rate.]

[Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval.]

[Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and highest rate.]

For southern bli ght (white mold) use 14 fl oz/A. Application: For best results, sufficient water volume must be used to provide thorough coverage. Quadris Top SBX can be applied by ground, chemigation, or aerial application. Use a minimum of 15 gal/A for ground applications. For aerial applications, use a minimum of 10 gal/A of water. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy. Specific Use Restrictions:

1. Do not apply more than 31 fl oz/A/year of Quadris Top SBX.
2. Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
3. Do not apply more than 2.0 lb ai/A/year of azoxystrobin-containing products.
4. Do not appl y within 7 days of harvest (7-day PHI).

Quadris Top SBX Fungicide Page 23

Crop

Target Diseases Use Rate fl oz product/A Remarks Chickpea (garbanzo bean) Alternaria Blight ( A. alternata)

Ascochyta Blight (A. rabiei)

Powdery Mildew (Leveillula taurica)

Rust (Uromyces ciceris- arietini) 7.0-7.5

Begin applications prior to disease onset when conditions are conducive for disease. Apply Quadris Top SBX on a 14-day schedule making no more than 2 sequential applications before alternating to another fungicide with a different mode of action.

The addition of a spreading/penetrating type adjuvant such as a non-ionic based surfactant or crop oil concentrate or blend is recommended.

[Optional language if label has a rate range: If disease pressure is high, use the highest rate.]

[Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval.]

[Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and hi ghest rate.] Application: For best results, sufficient water volume must be used to provide thorough coverage. Quadris Top SBX can be applied by ground, chemigation, or aerial application. Use a minimum of 15 gal/A for ground applications. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy. Specific Use Restrictions:

1. Do not apply more than 31 fl oz/A/year of Quadris Top SBX.
2. Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
3. Do not apply more than 1.5 lb ai/A/year of azoxystrobin-containing products.
4. Do not apply within 14 days of harvest (14-day PHI).

Quadris Top SBX Fungicide Page 24

Crop

Target Diseases Use Rate fl oz product/A Remarks Citrus Fruit Crop Group 10-10

Grapefruit Lemon Lime Orange (Sour and Sweet) Tangerine

Including all cultivars and/or hybrids of these

See complete list of citrus fruit crops below. Greasy Spot (Mycosphaerella citri) 5.6-8.5 Quadris Top SBX applications should begin prior to disease development and continue throughout the season on 7- to 21-day intervals following the resistance management guidelines. Applications may be made by ground or air. An adjuvant may be added at recommended rates. A horticultural spray oil should be used to improve control of greasy spot.

The addition of a spreading/penetrating type adjuvant such as a non-ionic based surfactant or crop oil concentrate or blend is recommended.

[Optional language if label has a rate range: If disease pressure is high, use the highest rate.]

[Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval.]

[Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and highest rate.]

Make no more than 2 sequential applications before alternating to another fungicide with a non- QoI (Group 11) different mode of action. Do not make more than 4 applications of Quadris Top SBX or other Group 11 fun gicides per year. Alternaria Leaf and Fruit Spot (Alternaria citri)

Anthracnose ( Colletotrichum spp.)

Black Spot ( Guignardia citricarpa)

Greasy Spot Rind Blotch (Mycosphaerella citri)

Melanose (Diaporthe citri)

Phomopsis Stem-End Rot ( Phomopsis citrii)

Post-Bloom Fruit Drop (PFD) (Colletotrichum acutatum)

Scab

(Elsinoe fawcettii) 5.6-8.5 Quadris Top SBX applications should begin prior to disease development and continue throughout the season on 7- to 21-day intervals following the resistance management guidelines. Applications may be made by ground or air. An adjuvant may be added at recommended rates. A horticultural spray oil should be used to improve control of greasy spot.

[Optional language if label has a rate range: If disease pressure is high, use the highest rate.]

[Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval.]

[Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and highest rate.]

Make no more than 2 sequential applications before alternating to another fungicide with a non- QoI (Group 11) different mode of action. Do not make more than 4 applications of Quadris Top SBX or other Group 11 fungicides per year.

Quadris Top SBX Fungicide Page 25

The addition of a spreading/penetrating type adjuvant such as a non-ionic based surfactant or crop oil concentrate or blend is recommended. Application: For best results, sufficient water volume must be used to provide thorough coverage. Quadris Top SBX can be applied by ground or aerial application. Use a minimum of 15 gal/A for ground applications. For aerial applications, use a minimum of 10 gal/A of water. Complete List of Citrus Fruit Crops: Australian desert lime (Eremocitrus glauca); Australian finger lime (Microcitrus australasica); Australian round lime (Microcitrus australis); Brown River finger lime (Microcitrus papuana); Calamondin (Citrofortunella microcarpa); Citron (Citrus medica); Citrus hybrids, Citrus spp., Eremocitrus spp., Fortunella spp., Microcitrus spp., and Poncirus spp.; Grapefruit (Citrus paradise); Japanese summer grapefruit (Citrus natsudaidai); Kumquat (Fortunella spp.); Lemon (Citrus limon); Lime (Citrus aurantiifolia); Mediterranean mandarin (Citrus deliciosa); Mount White lime (Microcitrus garrowayae); New Guinea wild lime (Microcitrus warburgiana); Orange, sour (Citrus aurantium); Orange, sweet (Citrus sinensis); Pummelo (Citrus maxima); Russell River lime (Microcitrus inodora); Satsuma mandarin (Citrus unshiu); Sweet lime (Citrus limetta); Tachibana orange (Citrus tachibana); Tahiti lime (Citrus latifolia); Tangelo (Citrus x tangelo); Tangerine (Mandarin) (Citrus reticulata); Tangor (Citrus nobilis); Trifoliate orange (Poncirus trifoliata); Uniq fruit (Citrus aurantium Tangelo group); cultivars, varieties and/or hybrids of these. Specific Use Restrictions:

1. Do not use Quadris Top SBX in citrus plant propagation nurseries.
2. Do not apply more than 34 fl oz/A/year of Quadris Top SBX.
3. Do not apply more than 0.5 lb ai/A/year of difenoconazole-containing products.
4. Do not apply more than 1.5 lb ai/A/year of azoxystrobin-containing products. 5 ) Ma y be applied the day of harvest (0-day PHI).

Quadris Top SBX Fungicide Page 26

Crop

Target Diseases Use Rate fl oz product/A Remarks Cotton (Subgroup 20C)

Aerolate mildew (Ramularia gossypii) Alternaria leaf spot (Alternaria spp) Anthracnose (Glomerella gossypii) Ascochyta blight (A.gossypii) Boll rots (Ascochyta gossypii, Alternaria spp., Diplodia spp., Phoma spp.) Cotton rust (Puccinia schedonnardi) Diplodia boll rot (Diplodia spp.) Hardlock (Fusarium verticillioides) Leafspots and blights (Alternaria spp., Ascochyta gossypii, Cercospora spp., Stemphyllium spp.) Southwesterrn cotton rust (Puccina cacabata, Puccinia spp.) Stemphyllium leaf spot (Stemphyllium spp.) Target spot (Cornyespora cassiicola ) 6 – 7.7* For best activity, apply Quadris Top SBX prior to or early in the disease development. An adjuvant may be added at specified rates.

For foliar disease control, the first application should be targeted approximately at pin-head square to first bloom or when conditions are conducive for disease development. For best control of target spot, adjust the GPA to ensure coverage of upper and lower leaves. Subsequent applications may be made on a 14-21 day interval.

Do not apply more than two sequential applications before alternating to a fungicide with a different mode of action.

*7.7 fl oz product/A contains 0.113 lb difenoconazole/A and 0.113 lb azoxystrobin/A. Application: For best results, sufficient water volume must be used to provide thorough coverage. Quadris Top SBX can be applied by ground, chemigation, or aerial application. For aerial applications, use a minimum of 5 gal/A of water. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy. Applicators should use care in making applications near non-target aquatic habitats. Specific Use Restrictions:

1. Do not apply more than 23.1 fl oz/A/year of Quadris Top SBX.
2. Do not apply more than 0.45 lb ai/A/year of azoxystrobin-containing products.
3. Do not apply more than 0.34 lb ai/A/year of difenoconazole-containing products.
4. Do not apply Quadris Top SBX within 45 days of harvest (45-day PHI).

Quadris Top SBX Fungicide Page 27

Crop

Target Diseases Use Rate fl oz product/A Remarks Cranberry

Bitter rot (Colletotrichum gloeosporioides)

Blotch rot (Physalospora vaccinia)

Cottonball (Monilinia oxycocci)

Fruit Rots (Physalospora vaccinia) Glomerella cingulata) (Coleophoma empetri)

Leaf rust (Pucciniastrum vaccinii)

Lophodermium Twig Blight (Lophodermium spp.)

Ripe rot (Coleophoma empetr i) 7 – 7.7* For best activity, apply Quadris Top SBX prior to or early in the disease development. An adjuvant may be added at specified rates. Apply on a 7-14 day interval.

Do not apply more than two sequential applications before alternating to a fungicide with a different mode of action.

*7-7.7 fl oz product/A contains 0.103-0.113 lb difenoconazole/A and 0.103-0.113 lb azoxystrobin/A. Application: For best results, sufficient water volume must be used to provide thorough coverage. Quadris Top SBX can be applied by ground, chemigation, or aerial application. For aerial applications, use a minimum of 5 gal/A of water. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficac y. Applicators should use care in making applications near non-target aquatic habitats. Specific Use Restrictions:

1. Do not apply more than 23.1 fl oz/A/year of Quadris Top SBX.
2. Do not apply more than 0.34 lb ai/A/year of difenoconazole-containing products.
3. Do not apply more than 1.5 lb ai/A/year of azoxystrobin-containing products.
4. Do not allow release of irrigation or flood water to non-target aquatic habitat for at least 14 days after the last application.
5. Do not apply when weather condit ions favor drift from treated areas to non-target aquatic habitat.
6. Do not treat fields used for aquaculture of fish or crustacean.
7. Do not drain water from treated fields into ponds used for aquaculture of fish or crustacean.
8. Do not use water drained from treated field to irrigate other crops.
9. Do not apply to flooded crops. 10 ) Do not apply Quadris Top SBX within 30 days of harvest (30-day PHI).

Quadris Top SBX Fungicide Page 28

Crop

Target Diseases Use Rate fl oz product/A Remarks Cucurbit Vegetables Crop Group 9

Cantaloupe Cucumber Honeydew Muskmelon Watermelon Pumpkin Squash Zucchini

Including cultivars and/or hybrids of these

See additional cucurbit crops below. Alternaria Leaf Blight ( A. cucumerina)

Alternaria Leaf Spot ( A. alternata)

Anthracnose ( Colletotrichum orbiculare)

Belly Rot ( Rhizoctonia solani)

Cercospora Leaf Spot ( C. citrullina)

Downy Mildew (Pseudoperonospora cubensis)

Gummy Stem Blight ( Didymella bryoniae)

Myrothecium Canker ( M. roridum)

Phoma Blight ( P. exigua)

Phyllosticta Leaf Spot ( P. cucurbitacearum)

Plectosporium Blight ( P. tabacinum)

Powdery Mildew (Sphaerotheca fuliginea, Erysiphe cichoracearum)

Septoria Leaf Blight

(S. cucurbitacearum) 7.0-7.5

Begin applications prior to disease onset when conditions are conducive for disease. Apply Quadris Top SBX on a 7- to 14-day schedule, making no more than 1 application of a QoI containing fungicide before alternating to another fungicide with a different mode of action.

The addition of a spreading/penetrating type adjuvant such as a non-ionic based surfactant or crop oil concentrate or blend is recommended.

[Optional language if label has a rate range: If disease pressure is high, use the highest rate.]

[Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval.]

[Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and highest rate.]

For belly rot control, the first application should be made at the 1- to 3-leaf crop stage with a second application just prior to vine tip or 10-14 days later, whichever occurs first. Application: For best results, sufficient water volume must be used to provide thorough coverage. Quadris Top SBX can be applied by ground, chemigation, or aerial application. Use a minimum of 15 gal/A for ground applications (20 for gummy stem blight). For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficac y. Complete List of Cucurbit Vegetables: Chayote (fruit); Chinese waxgourd (Chinese preserving melon); citron melon; cucumber; gherkin; gourd, edible (includes hyotan, cucuzza, hechima, Chinese okra); Momordica spp. (includes balsam apple, balsam pear, bittermelon, Chinese cucumber); muskmelon (includes cantaloupe); pumpkin; squash, summer; squash, winter (includes butternut squash, calabaza, hubbard squash, acorn squash, spaghetti squash); watermelon Specific Use Restrictions:

1. Do not apply more than 31 fl oz/A/year of Quadris Top SBX.
2. Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
3. Do not apply more than 1.5 lb ai/A/year of azoxystrobin-containing products. 4 ) Do not appl y within 1 day of harvest (1-day PHI).

Quadris Top SBX Fungicide Page 29

Crop

Target Diseases Use Rate fl oz product/A Remarks Filberts (Hazelnuts)

Eastern Filbert Blight ( Anisogramma anomala)

7.0-7.5

Begin applications prior to disease onset when conditions are conducive for disease. Apply Quadris Top SBX on a 14- to 21-day schedule making no more than 2 sequential applications before alternating to another fungicide with a non- Qol (Group 11) different mode of action.

The addition of a spreading/penetrating type adjuvant such as a non-ionic based surfactant or crop oil concentrate or blend is recommended.

[Optional language if label has a rate range: If disease pressure is high, use the highest rate.]

[Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval.]

[Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and hi ghest rate.] Application: For best results, sufficient water volume must be used to provide thorough coverage. Quadris Top SBX can be applied by ground or aerial application. Use a minimum of 15 gal/A for ground applications. For aerial applications, use a minimum of 10 gal/A of water. Specific Use Restrictions:

1. Do not apply more than 31 fl oz/A/year of Quadris Top SBX.
2. Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
3. Do not apply more than 1.2 lb ai/A/year of azoxystrobin-containing products.
4. Do not appl y within 45 days of harvest (45-day PHI).

Quadris Top SBX Fungicide Page 30

Crop

Target Diseases Use Rate fl oz product/A Remarks Fruiting Vegetables Crop Group 8-10

Peppers Bell Pepper Non-Bell Pepper Sweet Non-Bell Eggplant

Including all cultivars and/or hybrids of these

See Tomatoes section for specific directions.

See complete list of peppers and other fruiting vegetables below.

Anthracnose (Colletotrichum spp.)

Cercospora Leaf Spot (C. capsici)

Gray Leaf Spot (Stemphyllium solani)

Powdery Mildew (Oidiopsis sicula) 7.0-7.5

Begin applications prior to disease development and continue throughout the season on a 7- to 10- day interval. Make no more than 2 consecutive applications before switching to another effective fungicide with a different mode of action.

The addition of a spreading/penetrating type adjuvant such as a non-ionic based surfactant or crop oil concentrate or blend is recommended.

[Optional language if label has a rate range: If disease pressure is high, use the highest rate.]

[Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval.]

[Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and highest rate.]

The addition of a spreading/penetrating type ad juvant may enhance efficacy. Application: For best results, sufficient water volume must be used to provide thorough coverage. Quadris Top SBX can be applied by ground or aerial application. Use a minimum of 15 gal/A for ground applications. For aerial applications, use a minimum of 10 gal/A of water. Complete List of Peppers and Other Fruiting Vegetables: African eggplant; Bell pepper; Eggplant; Martynia; Non-bell pepper; Okra; Pea eggplant; Pepino; Roselle; Scarlet eggplant; cultivars, varieties; and/or hybrids of these. Specific Use Restrictions:

1. Do not apply more than 30 fl oz/A/year of Quadris Top SBX.
2. Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
3. Do not apply more than 1.0 lb ai/A/year of azoxystrobin-containing products.
4. Ma y be applied the day of harvest (0-day PHI).

Quadris Top SBX Fungicide Page 31

Crop

Target Diseases Use Rate fl oz product/A Remarks Grapes (except Concord, Concord Seedless, and Thomcord See Precaution under Remarks.)

(Fruit, small, vine climbing, except fuzzy kiwifruit – subgroup 13-07F)

See additional crops in this subgroup below. Alternaria Rot ( A. alternata)

Angular Leaf Spot ( Mycosphearella angulata)

Anthracnose ( Elsinoe ampelina)

Black Rot ( Guignarda bidwellii)

Downy Mildew ( Plasmopara viticola)

Leaf Blight ( Pseudocercospora vitis)

Phomopsis Cane and Leaf Spot ( P. viticola)

Powdery Mildew ( Uncinula necator)

Rotbrenner ( Pseudopezicula tracheiphila)

Septoria Leaf Spot ( S. ampelina)

Suppression only: Botrytis Bunch Rot ( B. cinerea) 7.0-7.5

For powdery mildew, begin at bud break and apply on a 10- to 21-day interval, making no more than 2 sequential applications before alternating to another fungicide with a non-QoI (Group 11) mode of action.

For all other diseases, begin applications prior to disease onset when conditions are conducive for disease. Apply Quadris Top SBX on a 10- to 14- day schedule, making no more than 2 sequential applications before alternating to another fungicide with a non-QoI (Group 11) mode of action.

For Phomopsis diseases, apply at bud break before shoots are 0.5 inches in length, and then again when shoots are 5-6 inches in length.

For black rot, begin when shoot length is 1-3 inches and continue on a 10-day interval.

[Optional language if label has a rate range: If disease pressure is high, use the highest rate.]

[Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval.]

[Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and highest rate.]

PRECAUTION: Avoid rates of methylated or ethylated vegetable oil/organosilicone adjuvants over 0.125% with Quadris Top SBX as grape leaf injury may occur.

PRECAUTION: On V. labrusca, V. labrusca hybrids and other non-viniferea hybrids where sensitivity is not known, the use of Quadris Top SBX by itself or in tank mixtures with materials that may increase uptake (adjuvants, foliar fertilizers) may result in leaf burning or other phytotoxic effects.

ATTENTION

Quadris Top SBX is extremely phytotoxic to certain apple varieties. Refer to caution in Use Precautions and Restrictions section of label. Complete list of small fruit vine climbing, except fuzzy kiwifruit, subgroup 13-07F: Amur river grape; gooseberry; grape; kiwifruit, hardy; maypop; schisandra berry; cultivars, varieties, and/or hybrids of these Application: For best results, sufficient water volume must be used to provide thorough coverage. Quadris Top SBX can be applied by ground or aerial application. Use a minimum of 15 gal/A for ground applications. For aerial applications, use a minimum of 10 gal/A of water.

Quadris Top SBX Fungicide Page 32

Specific Use Restrictions:

1. Do not apply more than 31 fl oz/A/year of Quadris Top SBX.
2. Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
3. Do not apply more than 1.5 lb ai/A/year of azoxystrobin-containing products. 4 ) Do not appl y within 14 days of harvest (14-day PHI).

Quadris Top SBX Fungicide Page 33

Crop

Target Diseases Use Rate fl oz product/A Remarks Guava

Alternaria Fruit Rot

Anthracnose (Colletotrichum gloeosporioides)

Suppression Rust (Puccinia psidii) 7 – 7.7* For best activity, apply Quadris Top SBX prior to or early in the disease development. An adjuvant may be added at specified rates. Apply on a 10-14 day interval.

Do not apply more than two sequential applications before alternating to a fungicide with a different mode of action.

*7-7.7 fl oz product/A contains 0.103-0.113 lb difenoconazole/A and 0.103-0.113 lb azoxystrobin/A. Application: For best results, sufficient water volume must be used to provide thorough coverage. Quadris Top SBX can be applied by ground, chemigation, or aerial application. For aerial applications, use a minimum of 10 gal/A of water. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficac y. Applicators should use care in making applications near non-target aquatic habitats. Specific Use Restrictions:

1. Do not apply more than 30.8 fl oz/A/year of Quadris Top SBX.
2. Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
3. Do not apply more than 1.5 lb ai/A/year of azoxystrobin-containing products.
4. Quadris Top SBX may be applied the day of harvest (0-day PHI).

Quadris Top SBX Fungicide Page 34

Crop

Target Diseases Use Rate fl oz product/A Remarks Papaya

Blossom blight and fruit rot (Colletotrichum gloeosporioides)

Alternaria fruit spot (A. alternata)

Powdery Mildew (Oidium spp.)

Brown Spot (Corynespora cassicola) 7 – 7.7* For best activity, apply Quadris Top SBX prior to or early in the disease development. An adjuvant may be added at specified rates. Apply on a 10-14 day interval.

Do not apply more than two sequential applications before alternating to a fungicide with a different mode of action.

*7-7.7 fl oz product/A contains 0.103-0.113 lb difenoconazole/A and 0.103-0.113 lb azoxystrobin/A. Application: For best results, sufficient water volume must be used to provide thorough coverage. Quadris Top SBX can be applied by ground, chemigation, or aerial application. For aerial applications, use a minimum of 10 gal/A of water. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficac y. Applicators should use care in making applications near non-target aquatic habitats. Specific Use Restrictions:

1. Do not apply more than 30.8 fl oz/A/year of Quadris Top SBX.
2. Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
3. Do not apply more than 1.5 lb ai/A/year of azoxystrobin-containing products.
4. Quadris Top SBX may be applied the day of harvest (0-day PHI).

Quadris Top SBX Fungicide Page 35

Crop

Target Diseases Use Rate fl oz product/A Remarks Pecans

Downy Spot ( Mycosphaerella caryigena)

Liver Spot ( Gnomonia caryae pv pecanae)

Pecan Scab ( Cladosporium caryigenum)

Powdery Mildew ( Microsphaera penicillata)

Vein Spot ( Gnomomia nerviseda)

Zonate Leaf Spot ( Grovesinia pyramidalis) 7.0-7.5

Begin applications prior to disease onset when conditions are conducive for disease. Apply Quadris Top SBX on a 14- to 21-day schedule, making no more than 2 sequential applications before alternating to another fungicide with a non- QoI (Group 11) mode of action.

The addition of a spreading/penetrating type adjuvant such as a non-ionic based surfactant or crop oil concentrate or blend is recommended.

[Optional language if label has a rate range: If disease pressure is high, use the highest rate.]

[Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval.]

[Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and highest rate.] Application: For best results, sufficient water volume must be used to provide thorough coverage. Quadris Top SBX can be applied by ground or aerial application. Use a minimum of 15 gal/A for ground applications. For aerial applications, use a minimum of 10 gal/A of water. Specific Use Restrictions:

1. Do not apply more than 31 fl oz/A/year of Quadris Top SBX.
2. Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
3. Do not apply more than 1.2 lb ai/A/year of azoxystrobin-containing products. 4 ) Do not appl y within 45 days of harvest (45-day PHI).

Quadris Top SBX Fungicide Page 36

Crop

Target Diseases Use Rate fl oz product/A Remarks Pistachios

Alternaria Late Blight ( Alternaria spp.)

Panicle and Shoot Blight ( Botryosphaeria dothidea)

Septoria Leaf Spot ( S. pistaciarum) 7.0-7.5

Begin applications prior to disease onset when conditions are conducive for disease. Apply Quadris Top SBX on a 14- to 21-day schedule, making no more than 2 sequential applications before alternating to another fungicide with a non- QoI (Group 11) mode of action.

The addition of a spreading/penetrating type adjuvant such as a non-ionic based surfactant or crop oil concentrate or blend is recommended.

[Optional language if label has a rate range: If disease pressure is high, use the highest rate.]

[Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval.]

[Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and hi ghest rate.] Application: For best results, sufficient water volume must be used to provide thorough coverage. Quadris Top SBX can be applied by ground or aerial application. Use a minimum of 15 gal/A for ground applications. For aerial applications, use a minimum of 10 gal/A of water. Specific Use Restrictions:

1. Do not apply more than 31 fl oz/A/year of Quadris Top SBX.
2. Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
3. Do not apply more than 1.5 lb ai/A/year of azoxystrobin-containing products.
4. Do not appl y within 14 days of harvest (14-day PHI).

Quadris Top SBX Fungicide Page 37

Crop

Target Diseases Use Rate fl oz product/A Remarks Potatoes

Black Dot (Colletotrichum coccodes)

Brown Spot (Alternaria alternata)

Early Blight (Alternaria solani)

Powdery Mildew (Erysiphe cichoracearum)

Septoria Leaf Spot (S. lycopersici) 7.0-7.5

Begin applications prior to disease development and continue throughout the season on a 7- to 14- day interval. Make no more than 2 consecutive applications before switching to another effective fungicide with a different mode of action.

The addition of a spreading/penetrating type adjuvant such as a non-ionic based surfactant or crop oil concentrate or blend is recommended.

[Optional language if label has a rate range: If disease pressure is high, use the highest rate.]

[Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval.]

[Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and highest rate.]

The addition of a spreading/penetrating type ad juvant may enhance efficacy. Application: For best results, use sufficient water volume to provide thorough coverage. Quadris Top SBX may be applied by ground, chemigation, or aerial application. Specific Use Restrictions:

1. Do not apply more than 31 fl oz/A/year of Quadris Top SBX.
2. Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
3. Do not apply more than 2.0 lb ai/A/year of azoxystrobin-containing products
4. Do not appl y within 14 days of harvest (14-day PHI).

Quadris Top SBX Fungicide Page 38

Crop

Target Diseases Use Rate fl oz product/A Remarks Rice

Sheath Blight (Rhizoctonia solani) Aggregate Sheath Spot (Rhizoctonia oryzae- sativae) Black Sheath Rot (Gaeumannomyces graminis var. graminis) Sheath Spot (Rhizoctonia oryzae) Stem Rot (Sclerotium oryzae) Brown Leaf spot (Cochliobolus miyabeanus) Leaf Smut (Entyloma oryzae) Narrow Brown Leaf spot (Cercospora oryzae) Kernel Smut (Neovossia barclayana)

Suppression of: Panicle Blast (Pyricularia grisea) False smut (Ustilaginoidea virens) 8.3* Apply 8.3 fl oz when disease is less than 4 inches above water line usually between panicle differentiation (PD) +5 days to PD +10 days or at initial sign of disease. For improved activity, add azoxystrobin at its labeled rate. Under heavy disease pressure and conditions favorable for disease development, a second application may be applied.

Quadris Top SBX must be applied as a preventative treatment for blast control and applied prior to favorable conditions for blast development. For panicle blast, an application should be applied at mid-boot to boot-split but prior to full head emergence. A second application should be applied when panicles are approximately 60-90% emerged from the boot (14 days later).

For improved control of blast, tank mix 8.3 fl oz/A Quadris Top SBX with azoxystrobin at its labeled rate. *8.3 fl oz product/A contains 0.122 lb difenoconazole/A and 0.122 lb azoxystrobin/A. Application: For best results, sufficient water volume must be used to provide thorough coverage. Quadris Top SBX can be applied by ground or aerial application. For aerial applications, use a minimum of 5 gal/A of water. Applicators should use care in makin g applications near non-target aquatic habitats. Specific Use Restrictions:

1. Do not treat rice fields used for aquaculture of fish or crustacean.
2. Do not apply when weather condition s favor drift from treated areas to non-target aquatic habitat.
3. Do not allow release of irrigation or flood water for at least 14 days after the last application.
4. Do not apply more than 16.6 fl oz/A/year of Quadris Top SBX.
5. Do not exceed 0.281 lb of azoxystrobin per application through any combination of products.
6. Do not apply more than 0.7 lb ai/A/year of azoxystrobin-containing products.
7. Do not apply more than 0.244 lb ai/A/year of difenoconazole-containing products.
8. Do not apply Quadris Top SBX within 28 days of harvest (28-day PHI).
9. Do not drain water from treated rice fields into ponds used for aquaculture of fish or crustacean. 10 ) Do not use water drained from treated field to irrigate other crops.

Quadris Top SBX Fungicide Page 39

Crop

Target Diseases Use Rate fl oz product/A Remarks Soybean Aerial Blight (Rhizoctonia solani)

Alternaria Leaf Spot ( Alternaria spp.)

Anthracnose ( Colletotrichum truncatum)

Brown Spot ( Septoria glycines)

Cercospora Blight and Leaf Spot ( C. kikuchii)

Frogeye Leaf Spot ( Cercospora sojina)

Pod and Stem Blight ( Diaporthe phaseolorum)

Powdery Mildew ( Microsphaera diffusa)

Rust (Phakopsora spp.) 7.0-7.5 Begin applications prior to disease onset when conditions are conducive for disease. Apply Quadris Top SBX on a 7- to 10-day schedule making no more than 2 sequential applications before alternating to another fungicide with a different mode of action.

The addition of a spreading/penetrating type adjuvant such as a non-ionic based surfactant or crop oil concentrate or blend is recommended.

[Optional language if label has a rate range: If disease pressure is high, use the highest rate.]

[Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval.]

[Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and highest rate.] Application: For best results, sufficient water volume must be used to provide thorough coverage. Quadris Top SBX can be applied by ground, chemigation, or aerial application. For aerial applications, apply in a minimum of 2 gallons/A of water. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficac y. Specific Use Restrictions:

1. Do not apply more than 14.8 fl oz/A/year of Quadris Top SBX.
2. Do not apply more than 0.22 lb ai/A/year of difenoconazole-containing products.
3. Do not apply more than 1.5 lb ai/A/year of azoxystrobin-containing products.
4. Do not feed soybean hay, forage and silage to livestock. 5 ) Do not appl y within 14 days of harvest (14-day PHI).

Quadris Top SBX Fungicide Page 40

Crop

Target Diseases Use Rate fl oz product/A Remarks Stone Fruit Crop Group 12-12 Apricots Cherries, Sweet Cherries, Tart Nectarines Peaches Plums Plumcot Prunes

Including all cultivars and/or hybrids of these Alternaria Spot and Fruit Rot ( A. alternata) Anthracnose ( Colletotrichum spp.) Brown Rot Blossom Blight and Fruit Rot ( Monilinia fructicola, M. laxa) Leaf Rust ( Tranzschelia discolor) Powdery Mildew ( Sphaerotheca pannosa, Podosphaera clandestina) Scab ( Cladosporium carpophilum) Shot Hole ( Wilsonomyces carpophilus) 7.0-7.5 For brown rot blossom blight, begin applications at early bloom and continue through petal fall.

For brown rot on fruit, apply as needed a maximum of two sprays during the pre-harvest period up to the day of harvest (minimum of a 7-day retreatment interval). If high inoculum and severe disease conditions persist, apply a registered fungicide that is non-Group 11 or non-Group 9.

Follow the brown rot blossom blight schedule. Make additional applications on a 10- to 14-day interval from the end of petal fall to harvest.

The addition of a spreading/penetrating type adjuvant such as a non-ionic based surfactant or crop oil concentrate or blend is recommended.

[Optional language if label has a rate range: If disease pressure is high, use the highest rate.]

[Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval.]

[Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and hi ghest rate.] Application: For best results, sufficient water volume must be used to provide thorough coverage. Quadris Top SBX can be applied by ground or aerial application. Stone fruit diseases are most effectively controlled by ground applications. Use a minimum of 15 gal/A for ground applications. For aerial applications, use a minimum of 10 gal/A of water. Specific Use Restrictions:

1. Do not apply more than 31 fl oz/A/year of Quadris Top SBX.
2. Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
3. Do not apply more than 1.5 lb ai/A/year of azoxystrobin-containing products.
4. Quadris Top SBX ma y be applied on the day of harvest (0-day PHI).

Quadris Top SBX Fungicide Page 41

Crop

Target Diseases Use Rate fl oz product/A Remarks Sugar beets

Cercospora Leaf Spot ( C. beticola)

Powdery Mildew ( Erysiphe polygoni)

7.0-7.5 Begin applications prior to disease development and continue throughout the season on a 10- to 21- day interval. Make no more than 2 consecutive applications before switching to another effective fungicide with a different mode of action.

The addition of a spreading/penetrating type adjuvant such as a non-ionic based surfactant or crop oil concentrate or blend is recommended.

[Optional language if label has a rate range: If disease pressure is high, use the highest rate.]

[Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval.]

[Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and highest rate.]

The addition of a spreading/penetrating type adjuvant such as a non-ionic surfactant or crop oil concentrate or blend is recommended when appl ying by ground or air. Application: For best results, use sufficient water volume to provide thorough coverage. Quadris Top SBX may be applied by ground, chemigation, or aerial application. Specific Use Restrictions:

1. Do not apply more than 31 fl oz/A/year of Quadris Top SBX.
2. Do not apply more than 2.0 lb ai/A/year of azoxystrobin-containing products.
3. Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
4. Do not appl y within 7 days of harvest (7-day PHI).

Quadris Top SBX Fungicide Page 42

Crop

Target Diseases Use Rate fl oz product/A Remarks Tomatoes

Tomatillo

Including all cultivars and/or hybrids of these

See complete list of tomato crops below.

Anthracnose (Colletotrichum spp.)

Black Mold (A. alternata)

Early Blight (Alternaria solani)

Gray Leaf Spot (Stemphylium botryosum)

Leaf Mold (Fulvia fulva)

Powdery Mildew (Leveillula taurica)

Septoria Leaf Spot (S. lycopersici)

Target Spot (Corynespora cassiicola)

4.5 Begin applications prior to disease development and continue throughout the season on a 7- to 10- day interval. Make no more than 2 consecutive applications before switching to another effective fungicide with a different mode of action.

[Optional language if label has a rate range: If disease pressure is high, use the highest rate.]

[Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval.]

[Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and highest rate.]

Use of Adjuvants: Under certain weather conditions (particularly high temperatures) Quadris Top SBX in combination with high rates of silicone- based or oil containing (petroleum or crop) additives or adjuvants may cause injury. Do not exceed 0.125% adjuvant (v/v). Consult a Syngenta representative for more information concerning additives or adjuvants.

A tank mixture with Dimethoate may cause crop injury.

On fresh market tomatoes, do not use adjuvants or tank mix Quadris Top SBX with an y EC product. Application: For best results, use sufficient water volume to provide thorough coverage. Quadris Top SBX may be applied by ground, chemigation, or aerial application. Complete List of Tomato Crops: Bush tomato; Cocona; Currant tomato; Garden huckleberry; Goji berry; Groundcherry; Naranjilla; Sunberry; Tomatillo; Tomato; Tree tomato; cultivars, varieties, and/or hybrids of these. Specific Use Restrictions:

1. Do not apply more than 26 fl oz/A/year of Quadris Top SBX.
2. Do not apply until 21 days after transplanting or 35 days after seeding.
3. Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
4. Do not apply more than 0.6 lb ai/A/year of azoxystrobin-containing products.
5. Ma y be applied the day of harvest (0-day PHI).

Quadris Top SBX Fungicide Page 43

Crop

Target Diseases Use Rate fl oz product/A Remarks Tree Nuts Crop Group 14-12

Beechnut Brazil Nut Butternut Cashew Chestnut Chinquapin Hickory Macadamia Walnut, Black Walnut, English

See specific Directions for Almonds Filberts Pecans Pistachios

Foliar Diseases

7.0-7.5 Begin applications prior to disease onset when conditions are conducive for disease. Apply Quadris Top SBX on a 14- to 21-day schedule making no more than 2 sequential applications before alternating to another fungicide with a non- QoI (Group 11) mode of action.

The addition of a spreading/penetrating type adjuvant such as a non-ionic based surfactant or crop oil concentrate or blend is recommended.

[Optional language if label has a rate range: If disease pressure is high, use the highest rate.]

[Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval.]

[Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and hi ghest rate.] Application: For best results, sufficient water volume must be used to provide thorough coverage. Quadris Top SBX can be applied by ground or aerial application. Use a minimum of 15 gal/A for ground applications. For aerial applications, use a minimum of 10 gal/A of water. Specific Use Restrictions:

1. Do not apply more than 31 fl oz/A/year of Quadris Top SBX.
2. Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
3. Do not apply more than 1.2 lb ai/A/year of azoxystrobin-containing products.
4. Do not appl y within 45 days of harvest (45-day PHI).

Quadris Top SBX Fungicide Page 44

Crop

Target Diseases Use Rate fl oz product/A Remarks Vegetables, Tuberous and Corm, Subgroup 1C

For listing of crops in this group, see below.

See Potatoes for specific use directions. Ascochyta Leaf Spot (A. cynarae)

Black Dot (Colletotrichum coccodes)

Brown Spot (Alternaria alternata)

Early Blight (Alternaria spp.)

Powdery Mildew (Erysiphe cichoracearum)

Rust (Uromyces betae, Puccinia helianthi)

Septoria Leaf Spot (Septoria spp.)

7.0-7.5

Begin applications prior to disease development and continue throughout the season on a 7- to 14- day interval. Make no more than 2 consecutive applications before switching to another effective fungicide with a different mode of action.

The addition of a spreading/penetrating type adjuvant such as a non-ionic based surfactant or crop oil concentrate or blend is recommended.

[Optional language if label has a rate range: If disease pressure is high, use the highest rate.]

[Optional language if label has a single rate and interval range: If disease pressure is high, use the shortest interval.]

[Optional language if label has a rate range and interval range: If disease pressure is high, use the shortest interval and highest rate.]

The addition of a spreading/penetrating type ad juvant may enhance efficacy. Application: For best results, sufficient water volume must be used to provide thorough coverage. Quadris Top SBX can be applied by ground or aerial application. Use a minimum of 15 gal/A for ground applications. For aerial applications, use a minimum of 10 gal/A of water. Complete List of Vegetables, Tuberous and Corm Subgroup 1C: Arracacha, Arrowroot, Artichoke (Chinese and Jerusalem), Canna (Edible), Cassava (bitter and sweet), Chayote (root), Chufa, Dasheen , Ginger, Leren, Potato, Sweet Potato, Tanier, Tumeric, Yam (bean and true). Specific Use Restrictions:

1. Do not apply more than 31 fl oz/A/year of Quadris Top SBX.
2. Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
3. Do not apply more than 2.0 lb ai/A/year of azoxystrobin-containing products.
4. Do not appl y within 14 days of harvest (14-day PHI).

Quadris Top SBX Fungicide Page 45

Crop

Target Diseases Use Rate fl oz product/A Remarks Watercress

Cercospora leafspot (Cercospora spp.)

7.0

For best activity, apply Quadris Top SBX prior to or early in the disease development. An adjuvant may be added at specified rates. Apply on a 7-14 day interval. For applications made to watercress, production fields must be drained of water at least 24 hours prior to application and water must not be reapplied to the field for a minimum of 24 hours following the application.

Do not apply more than two sequential applications before alternating to a fungicide with a different mode of action. *7.0 fl oz product/A contains 0.103 lb difenoconazole/A and 0.103 lb azoxystrobin/A. Application: For best results, sufficient water volume must be used to provide thorough coverage. Quadris Top SBX can be applied by ground, chemigation, or aerial application. For aerial applications, use a minimum of 5 gal/A of water. Applicators should use care in making applications near non-target aquatic habitats. Specific Use Restrictions:

1. Do not apply directly to water and do not allow water in a treated field for at least 24 hours.
2. Do not apply more than 28 fl oz/A/year of Quadris Top SBX.
3. Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
4. Do not apply more than 1.5 lb ai/A/year of azoxystrobin-containing products.
5. Do not apply more than 0.75 lb ai of azoxystrobin-containing products per acre per cutting. 6 ) Do not appl y Quadris Top SBX within 30 days of harvest (30-day PHI).

Quadris Top SBX Fungicide Page 46

Crop

Target Diseases Use Rate fl oz product/A Remarks Wild Rice

Helminthosporium leaf blight

Brown Spot (Bipolaris spp.) 8.3* Apply 8.3 fl oz/A at both booting and heading. Minimum re-treatment interval is 14 days.

*8.3 fl oz product/A contains 0.122 lb difenoconazole/A and 0.122 lb azoxystrobin/A. Application: For best results, sufficient water volume must be used to provide thorough coverage. Quadris Top SBX can be applied by ground or aerial application. For aerial applications, use a minimum of 5 gal/A of water. Applicators should use care in making applications near non-target aquatic habitats. Specific Use Restrictions:

1. Do not treat rice fields used for aquaculture of fish or crustacean.
2. Do not apply when weather condition s favor drift from treated areas to non-target aquatic habitat.
3. Do not allow release of irrigation or flood water for at least 14 days after the last application.
4. Do not apply more than 16.6 fl oz/A/year of Quadris Top SBX.
5. Do not apply more than 0.7 lb ai/A/year of azoxystrobin-containing products.
6. Do not apply more than 0.244 lb ai/A/year of difenoconazole-containing products.
7. Do not apply Quadris Top SBX within 28 days of harvest (28-day PHI).
8. Do not drain water from treated rice fields into ponds used for aquaculture of fish or crustacean. 9 ) Do not use water drained from treated field to irri gate other crops.

Quadris Top SBX Fungicide Page 47

Quadris Top SBX Rate Conversion Table for Food Use

Fl oz product/acre Lb ai azox ystrobin Lb ai difenoconazole 4.5 0.067 0.067 5.6 0.082 0.082 6.5 0.096 0.096 7.0 0.103 0.103 7.5 0.110 0.110 7.7 0.113 0.113 8.0 0.118 0.118 8.3 0.122 0.122 8.5 0.125 0.125

STORAGE AND DISPOSAL

Do not contaminate water, food, or feed by storage or disposal.

Pesticide Storage

Store in original container only. Store in a cool, dry and well-ventilated place. Protect from excessive heat. Keep container closed when not in use. Do not store near food or feed.

Pesticide Disposal

Pesticide wastes may be toxic. Improper disposal of unused pesticide, spray mixture, or rinse water is a violation of Federal Law. If these wastes cannot be used according to label instructions, contact your State Pesticide or Environmental Control Agency, or the Hazardous Waste representative at the nearest EPA Regional Office for guidance in proper disposal methods.

Container Handling [less than or equal to 5 gallons]

Non-refillable container. Do not reuse or refill this container. Triple rinse container (or equivalent) promptly after emptying. Triple rinse as follows: empty the remaining contents into application equipment or a mix tank and drain for 10 seconds after the flow begins to drip. Fill the container ¼ full with water and recap. Shake for 10 seconds. Pour rinsate into application equipment or a mix tank or store rinsate for later use or disposal. Drain for 10 seconds after the flow begins to drip. Repeat this procedure two more times. Then offer for recycling if available or puncture and dispose of in a sanitary landfill, or by incineration, or by other procedures approved by state and local authorities.

Container Handlin g [greater than 5 gallons – mini-bulk]

Quadris Top SBX Fungicide Page 48

Non-refillable container. Do not reuse or refill this container. Triple rinse container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank. Fill the container ¼ full with water. Replace and tighten closures. Tip container on its side and roll it back and forth, ensuring at least one complete revolution, for 30 seconds. Stand the container on its end and tip it back and forth several times. Turn the container over onto its other end and tip it back and forth several times. Empty the rinsate into application equipment or a mix tank or store rinsate for later use or disposal. Repeat this procedure two more times. Then offer for recycling if available or puncture and dispose of in a sanitary landfill, or by incineration, or by other procedures approved by state and local authorities.

Container Handling [greater than 5 gallons – bulk]

Refillable container. Refill this container with pesticide only. Do not reuse the container for any other purpose. Cleaning the container before final disposal is the responsibility of the person disposing of the container. Cleaning before refilling is the responsibility of the refiller. To clean container before final disposal, empty the remaining contents from this container into application equipment or mix tank. Fill the container about 10 percent full with water. Agitate vigorously or recirculate water with the pump for 2 minutes. Pour or pump rinsate into application equipment or rinsate collection system. Repeat this rinsing procedure two more times. Then offer for recycling if available or puncture and dispose of in a sanitary landfill, or by incineration, or by other procedures approved by state and local authorities.

CONTAINER IS NOT SAFE FOR FOOD, FEED, OR DRINKING WATER.

Quadris Top® SBX and the SYNGENTA Logo are Trademarks of a Syngenta Group Company

©201X Syngenta

For non-emergency (e.g., current product information), call Syngenta Crop Protection at 1-800-334-9481.

Manufactured for: Syngenta Crop Protection, LLC P.O. Box 18300 Greensboro, North Carolina 27419-8300

Quadris Top SBX Fungicide 1554 MAS 0218 AMEND-B 0519-CL – ep – 10-28-25 000100-01554.20190515B.QUADRIS_TOP_SBX-AMEND-0519-CL