crop-chem-docs/corpus/epa_ppls/100-1596.md

Plentrix¿

• EPA Reg No: 100-1596
• Registrant: SYNGENTA CROP PROTECTION, LLC
• Signal word: Caution
• Active ingredients: Metalaxyl-M (10.9%); Azoxystrobin (28.2%)
• Label accepted: 2025-12-04
• Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000100-01596-20251204.pdf

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December 4, 2025

Nestor Algarin Regulatory Product Manager Syngenta Crop Protection, LLC P.O. Box 18300 Greensboro, NC 27419

Subject: Label Amendment - Registrati on Review Mitigation for Mefenoxam and Azoxystrobin Product Name: Plentrix EP A Registration Number: 100-1596 Case Number: 671142 and 671145 Application Date: November 21, 2022

Dear Nestor Algarin:

The Agency, in accordance with the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), as amended, has completed reviewing all the information submitted with your application to support the Registration Review of the above referenced product in connection with the Metalaxyl/Mefenoxam and Azoxystrobin Interim Decisions, and has concluded that your submission is acceptable. The label referred to above, submitted in connection with registration under FIFRA, as amended, is acceptable.

Should you wish to add/retain a reference to the company’s website on your label, then please be aware that the website becomes labeling under the Federal Insecticide, Fungicide, and Rodenticide Act and is subject to review by the Agency. If the website is false or misleading, the product would be misbranded and unlawful to sell or distribute under FIFRA section 12(a)(1)(E). 40 CFR 156.10(a)(5) list examples of statements EPA may consider false or misleading. In addition, regardless of whether a website is referenced on your product’s label, claims made on the website may not substantially differ from those claims approved through the registration process. Therefore, should the Agency find or if it is brought to our attention that a website contains false or misleading statements or claims substantially differing from the EPA approved registration, the website will be referred to the EPA’s Office of Enforcement and Compliance Assurance.

A stamped copy of your labeling is enclosed for your records. This labeling supersedes all previously accepted labeling and must be used at your next label printing. You must

Page 2 of 2 EPA Reg. No. 100-1596 Case No. 671142 and 671145

submit one copy of the final printed labeling before you release the product for shipment with the new labeling. In accordance with 40 CFR 152.130(c), you may distribute or sell this product under the previously approved labeling for 12 months from the date of this letter. After 12 months, you may only distribute or sell this product if it bears this new revised labeling or subsequently approved labeling. “To distribute or sell” is defined under FIFRA section 2(gg) and its implementing regulation at 40 CFR 152.3.

If you have any questions about this letter, please contact Concepción Rodríguez by phone at 202-566-0820, or via email at rodriguez.concepcion@epa.gov.

S i n c e r e l y ,

Julie Javier, Team Leader Risk Mitigation and Implementation Branch 4 Pesticide Re-Evaluation Division Office of Pesticide Programs

ENCLOSURE: Stamped label

[Master Label] MEFENOXAM GROUP 4 FUNGICIDE AZOXYSTROBIN GROUP 11FFUNGICIDE Plentrix™ Fungicide x For control of diseases on ornamental plants; ornamental bulb, corm and tuber crops; conifers; Christmas trees; vegetable plants and non-bearing fruit and nut plants. x For use in greenhouses and nurseries (including field- and container-grown plants grown outdoors and in shade houses, lath houses and other ornamental production structures), conifer and forest nurseries, forestry production, retail nurseries, residential and commercial landscapes, and interior plantscapes. x For control of diseases on vegetable transplants grown for sale to consumers (outdoor use only). Active Ingredients: Azoxystrobin*: .........................................................................................................28.2% Mefenoxam**:.......................................................................................................... 10.9% Other Ingredients: 60.9% Total: 100.0% *CAS No. 131860-33-8 **CAS No. 70630-17-0 Plentrix™ is formulated as a suspension concentrate (SC) and contains 2.68 lb of azoxystrobin and 1.04 lb of mefenoxam per gallon. KEEP OUT OF REACH OF CHILDREN. CAUTION/PRECAUCIÓN Si usted no entiende la etiqueta, busque a alguien para que se la explique a usted en detalle. (If you do not understand the label, find someone to explain it to you in detail.) See additional precautionary statements and directions for use inside booklet. EPA Reg. 100-1596 EPA Est.

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Net Contents Dec 4, 2025 100-1596 Dec 4, 2025 100-1596

Plentrix 2 TABLE OF CONTENTS

1.0 FIRST AID 2.0 PRECAUTIONARY STATEMENTS 2.1 Hazards to Humans and Domestic Animals 2.2 Personal Protective Equipment (PPE) 2.3 Environmental Hazards DIRECTIONS FOR USE 3.0 PRODUCT INFORMATION 3.1 Integrated Pest Management (IPM) 3.2 Resistance Management 4.0 APPLICATION DIRECTIONS 4.1 Methods of Application 4.2 Application Equipment 4.3 Application Volume and Spray Coverage 4.4 Mixing Directions 4.5 Application through Irrigation Systems (Chemigation) 5.0 RESTRICTIONS AND PRECAUTIONS 5.1 Use Restrictions 5.2 Use Precautions 5.3 Spray Drift Management 6.0 ORNAMENTAL USE DIRECTIONS 6.1 Ornamentals – Soil Diseases (Container-Grown Plants) 6.2 Ornamentals – Soil Diseases (Plants Grown in Ground) 6.3 Ornamentals – Foliar Diseases 7.0 CONIFER USE DIRECTIONS 7.1 Conifers in Nurseries 7.2 Conifers in Plantations and Forestry Production 8.0 VEGETABLE PLANT USE DIRECTIONS 8.1 Brassica, Leafy Greens Subgroup 8.2 Bulb Vegetables 8.2 Cucurbits 8.4 Fruiting Vegetables (except Cucurbits) 8.5 Herbs (Fresh and Dried) 8.6 Leafy Vegetables (except Brassica) 8.7 Tomato 9.0 STORAGE AND DISPOSAL 10.0 CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY

Plentrix 3 1.0 FIRST AID FIRST AID If in eyes x Hold eye open and rinse slowly and gently with water for 15-20 minutes. x Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye. x Call a poison control center or doctor for treatment advice. If swallowed x Call a poison control center or doctor immediately for treatment advice. x Have person sip a glass of water if able to swallow. x Do not induce vomiting unless told to do so by the poison control center or doctor. x Do not give anything to an unconscious person. If on skin or clothing x Take off contaminated clothing. x Rinse skin immediately with plenty of water for 15-20 minutes. x Call a poison control center or doctor for treatment advice. If inhaled x Move person to fresh air. x If person is not breathing, call 911 or an ambulance, then give artificial respiration, preferably mouth-to-mouth, if possible. x Call a poison control center or doctor for treatment advice. Have the product container or label with you when calling a poison control center or doctor, or going for treatment. SYNGENTA HOTLINE NUMBER For 24-Hour Medical Emergency Assistance (Human or Animal) or Chemical Emergency Assistance (Spill, Leak, Fire, or Accident), Call 1-800-888-8372

2.0 PRECAUTIONARY STATEMENTS 2.1 Hazards to Human and Domestic Animals CAUTION Causes moderate eye irritation. Avoid contact with eyes or clothing. Harmful if swallowed. Wash thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco, or using the toilet. Wear protective eyewear, if appropriate.

2.2 Personal Protective Equipment (PPE) Applicators and other handlers must wear: x Long-sleeved shirt and long pants

Plentrix 4 x Chemical-resistant gloves made of barrier laminate, butyl rubber t 14 mils, nitrile rubber t 14 mils, neoprene rubber t 14 mils, natural rubber t 14 mils, polyethylene, polyvinyl chloride (PVC) t 14 mils, or Viton™ t 14 mils x Shoes plus socks x In addition, mixers/loaders/applicators using mechanically pressurized handwands, except when applying to Christmas tree farms, nursery ornamentals, landscaping, must wear a minimum of a NIOSH-approved particulate filtering facepiece respirator with any N, R, or P filter; OR a NIOSH-approved elastomeric particulate respirator with any N, R, or P filter; OR a NIOSH-approved powered air purifying respirator with HE filters.

Respirator fit testing, medical qualification, and training Using a program that conforms to OSHA’s requirements (see 29 CFR Part 1910.134), employers must verify that any handler who uses a respirator is: x Fit-tested and fit-checked, x Trained, and x Examined by a qualified medical practitioner to ensure physical ability to safely wear the style of respirator to be worn. A qualified medical practitioner is a physician or other licensed health care professional who will evaluate the ability of a worker to wear a respirator. The initial evaluation consists of a questionnaire that asks about medical conditions (such as a heart condition) that would be problematic for respirator use. If concerns are identified, then additional evaluations, such as a physical exam, might be necessary. The initial evaluation must be done before respirator use begins. Handlers must be reexamined by a qualified medical practitioner if their health status or respirator style or use- conditions change.

Upon request by local/state/federal/tribal enforcement personnel, employers must provide documentation demonstrating how they have complied with these requirements.

2.2.1 USER SAFETY REQUIREMENTS Follow the manufacturer’s instructions for cleaning/maintaining PPE. If no such instructions for washables exist, use detergent and hot water. Keep and wash PPE separately from other laundry.

2.2.2 ENGINEERING CONTROL STATEMENTS When handlers use closed systems, enclosed cabs, or aircraft in a manner that meets the requirements listed in the Worker Protection Standard (WPS) for agricultural pesticides [40 CFR 170.240(d)(4-6)], the handler PPE requirements may be reduced or modified as specified in the WPS.

User Safety Recommendations

Users should: x Wash hands before eatin g, drinking, chewing gum, using tobacco or using the toilet.

Plentrix 5 x Remove clothing/PPE immediately if pesticide gets inside. Then wash thoroughly and put on clean clothing. x Remove PPE immediately after handling this product. Wash the outside of gloves before removing. As soon as possible, wash thoroughly and change into clean clothing.

2.3 Environmental Hazards This product is toxic to fish and aquatic invertebrates. Azoxystrobin can be persistent for several months or longer. For terrestrial uses: Do not apply directly to water, or to areas where surface water is present, or to intertidal areas below the mean high water mark. Drift and runoff may be hazardous to aquatic organisms in water adjacent to treated areas. Do not contaminate water when disposing of equipment washwater or rinsate.

2.3.1 GROUND WATER ADVISORY Azoxystrobin, mefenoxam, and a degradate of azoxystrobin are known to leach through soil to groundwater under certain conditions as a result of label use. These chemicals may leach into groundwater if used in areas where soils are permeable, particularly where the water table is shallow.

2.3.2 SURFACE WATER ADVISORY This product may impact surface water quality due to runoff of rain water. This is especially true for poorly draining soils and soils with shallow groundwater. This product is classified as having a high potential for reaching surface water via runoff for several months or more after application. A level, well-maintained vegetative buffer strip between areas to which this product is applied and surface water features such as ponds, streams, and springs will reduce the potential loading of azoxystrobin and a degradate of azoxystrobin from runoff water and sediment. Runoff of this product will be reduced by avoiding applications when rainfall or irrigations is expected to occur within 48 hours.

Notify state and/or federal authorities and Syngenta immediately if you observe any adverse environmental effects due to use of this product.

DIRECTIONS FOR USE

It is a violation of federal law to use this product in a manner inconsistent with its labeling.

Do not apply this product in a way that will contact workers or other persons, either directly or through drift. Only protected handlers may be in the area during application. For any requirements specific to your state or tribe, consult the agency responsible for pesticide regulation.

Plentrix 6 FAILURE TO FOLLOW DIRECTIONS AND PRECAUTIONS ON THIS LABEL MAY RESULT IN CROP INJURY AND/OR POOR DISEASE CONTROL

AGRICULTURAL USE REQUIREMENTS

Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR Part 170. This Standard contains requirements for the protection of agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of agricultural pesticides. It contains requirements for training, decontamination, notification, and emergency assistance. It also contains specific instructions and exceptions pertaining to the statements on this label about personal protective equipment (PPE) and restricted-entry interval. The requirements in this box only apply to uses of this product that are covered by the Worker Protection Standard.

Do not enter or allow worker entry into treated areas during the restricted-entry interval (REI) of 48 hours.

Exception: If product is drenched or soil incorporated, the Worker Protection Standard, under certain circumstances, allows workers to enter the treated area if there will be no contact with anything that has been treated. No restricted-entry interval (REI) is required following a soil incorporated or a soil drench application.

PPE required for early entry to treated areas that is permitted under the Worker Protection Standard and that involves contact with anything that has been treated, such as plants, soil, or water is: x Coveralls x Chemical-resistant gloves made of barrier laminate, butyl rubber t 14 mils, nitrile rubber t 14 mils, neoprene rubber t 14 mils, natural rubber t 14 mils, polyethylene, polyvinyl chloride (PVC) t 14 mils, or Viton t 14 mils x Shoes plus socks

NON-AGRICULTURAL USE REQUIREMENTS

The requirements in this box apply to uses of this product that are NOT within the scope of the Worker Protection Standard for agricultural pesticides (40 CFR Part 170). The WPS applies when this product is used to produce agricultural plants on farms, forests, nurseries, or greenhouses.

Do not enter treated areas without protective clothing until sprays have dried.

Maximum usage when applying both metalaxyl- and mefenoxam-containing products to the same crop within the same season: Do not apply more than the

Plentrix 7 maximum yearly total application rate for the active ingredient as stated on the label of the product containing the lowest yearly total on that crop.

3.0 PRODUCT INFORMATION Read all label directions before use. All applications must be made according to the use directions that follow.

x Plentrix is a systemic fungicide that provides control of damping off, root and stem diseases caused by Pythium and Phytophthora spp., Rhizoctonia solani, Sclerotium rolfsii, and Fusarium spp. and foliar diseases caused by Phytophthora spp. (including Phytophthora ramorum), Rhizoctonia solani, and downy mildew fungi. x Apply Plentrix as a preventative treatment prior to infection for listed plant diseases. x Plentrix is a member of Syngenta’s Plant Performance™ product line and may also improve the yield and/or quality of the crop. These additional benefits are due to the positive effects on plant physiology. The effects may vary according to factors such as the species, variety and environment.

3.0.1 PLANT SAFETY Plentrix has been shown to be safe when applied at the specified rates to the ornamentals listed in Section 6.0, conifers listed in Section 7.0, and vegetable plants listed in Section 8.0, as well as the tolerant varieties of ornamental crabapple species listed below. Ornamentals that are sensitive to Plentrix are listed in Section 5.1.1. However, due to the large number of genera, species and varieties of ornamental greenhouse, nursery and landscape plants, it is impossible to test every one for tolerance to Plentrix. Neither the manufacturer nor the seller has determined whether Plentrix can be used safely on genera, species, or varieties of ornamental and nursery plants not specified on this label. The user should conduct small-scale testing at the recommended rates to ensure plant safety prior to broad-scale commercial use on plant genera and species not listed in this label. When using an adjuvant or tank-mix partner, the user should conduct small-scale testing at the specified rates to ensure plant safety prior to broad-scale commercial use.

Plentrix 8 Tolerant Varieties of Ornamental Crabapple Species (Genus Malus)

Callaway Golden Raindrops Mary Potter Selkirk Carmine (M. atrosanguinea) Hopa Molten Lava Sentinel Candymint Sargent Indian Magic New Centennial Silver Moon Christmas Holly Island Ormiston Roy Silverdrift David Jackii (M. baccata var. jackii) Pink Satin Sinai Fire Dolgo Japanese Flowering Crabapple (M. floribunda) Prairie Maid Sugar Tyme Donald Wyman Katherine Prairiefire Van Eseltine Dorothea Lancelot Profusion White Angel Doubloons Louisa Ralph Shay Wild crabapple (M. coronaria) Eleyi Malus x zumi var. calocarpa Red Baron Winter Gold Evereste M. sargentii Red Jade Eyelynn Manchurian (M. baccata var. mandshurica) Sargent

3.0.2 DISEASE SUPPRESSION If a use indicates suppression, it refers to erratic control from fair to good, or consistent control at a level below that obtained with products registered for control.

3.1 Integrated Pest (Disease) Management (IPM) x Plentrix should be integrated into an overall disease and pest management strategy whenever the use of a fungicide is required. x Cultural practices known to reduce disease development should be followed, including the selection of varieties with disease tolerance, removal of plant debris in which inoculum resides, and proper timing and placement of irrigation. x Consult your local agricultural authorities for additional IPM strategies established for your area. x Plentrix may be used in State Agricultural Extension advisory (disease forecasting) programs which recommend application timing based on environmental factors favorable for disease development.

3.2 Resistance Management MEFENOXAM GROUP 4 FUNGICIDE AZOXYSTROBIN GROUP 11 FFUNGICIDE

For resistance management, please note that Plentrix contains both a Group 4/[mefenoxam] and Group 11/[azoxystrobin] fungicide. Any fungal population may

Plentrix 9 contain individuals naturally resistant to Plentrix and other Group 4 or Group 11 fungicides. A gradual or total loss of pest control may occur over time if these fungicides are used repeatedly in the same fields. Appropriate resistance management strategies should be followed.

Mefenoxam belongs to the phenylamide class of chemistry which interferes with fungal RNA synthesis. Azoxystrobin belongs to the strobilurin class of chemistry which disrupts cellular respiration and energy generation.

To delay fungicide resistance, take one or more of the following steps:

x Rotate the use of Plentrix or other Group 4 or Group 11 fungicides within a growing season sequence with different groups that control the same pathogens. x Use tank mixtures with fungicides from a different group that are equally effective on the target pest when such use is permitted. Use at least the minimum application rate as labeled by the manufacturer. x Adopt an integrated disease management program for fungicide use that includes scouting, uses historical information related to pesticide use, and which considers host plant resistance, impact of environmental conditions on disease development, disease thresholds, as well as cultural, biological and other chemical control practices. x Where possible, make use of predictive disease models to effectively time fungicide applications. Note that using predictive models alone is not sufficient to manage resistance. x Monitor treated fungal populations for resistance development. x Contact your local Syngenta Representative, retailer, or extension specialist for any additional pesticide resistance-management and/or IPM recommendations for specific crops and pathogens. x For further information or to report suspected resistance contact Syngenta at 1-866- Syngent(a) (866-796-4368). You can also contact your pesticide distributor or university extension specialist to report resistance.

As part of a resistance management strategy: x Apply no more than two (2) sequential drench or soil applications before rotating to a non-Group 4 and 11 fungicide, unless otherwise stated in the specific use directions. x Apply only one (1) foliar application before rotating to a non-Group 4 or 11 fungicide for two sequential foliar applications before reapplying Plentrix. x Use Plentrix in rotation or in tank mix with an effective fungicide with a different mode of action – one that provides satisfactory disease control when used alone at the mixture rate. x Utilize Integrated Pest Management (IPM) pr actices in your program which can help reduce disease development and spread.

4.0 APPLICATION DIRECTIONS

Plentrix 10 4.1 Methods of Application Plentrix may be applied as a drench, soil surface spray (broadcast or banded), or as a stem and foliar spray. Plentrix may also be incorporated into a pre-potting growing media for subsequent seeding or transplanting of ornamentals. Apply Plentrix at the rates specified in Sections 6.1 and 6.2. Applications can be made by ground or via chemigation as specified.

4.1.1 DRENCH APPLICATION x Drench application is limited to use on Ornamentals and other listed crops. x Prepare the Plentrix drench solution according to Section 6.1. x Plentrix may be applied to ornamentals in outdoor nurseries, forest nurseries, greenhouses, lath and shade houses, interiorscapes, and commercial and residential landscapes. x Apply enough drench solution to thoroughly wet the root zone of the plants without leaching through the container.

Plentrix 11

4.1.2 FOLIAR AND STEM APPLICATIONS x Plentrix may be applied as a spray to control downy mildew diseases and foliar diseases caused by Phytophthora spp. (including Phytophthora ramorum) and Rhizoctonia solani. x Apply thoroughly to all parts of the foliage and stems.

4.1.3 SOIL SURFACE SPRAYS x Apply listed use rates per 1,000 sq ft as a broadcast or banded spray to planting media in sufficient water to reach the root zone. Irrigate within 24 hours of application.

4.1.4 PRE-POTTING GROWING MEDIA MIX x Blend the specified use rate of Plentrix into a sufficient quantity of water. Uniformly mix this solution onto one (1) cubic yard of potting media. x Uniform mixing can be accomplished by placing the potting mix in a rotating drum and spraying the Plentrix solution onto the mix while the drum is rotating. x It is recommended that this media treatment be prepared just prior to use. Mix only enough for current use. Restriction: Do not store.

4.1.5 BANDED APPLICATIONS Calculate the amount of Plentrix to apply as follows:

Band width in inches X Broadcast rate = Amount needed per acre Row width in inches Per acre

4.2 Application Equipment Plentrix may be applied with application equipment commonly used for greenhouse and nursery plant production. See Section 4.5 for information about chemigation equipment. x Spray equipment configuration should be arranged to provide accurate, uniform and thorough drench application to the target crop and minimize potential for spray drift. x To ensure accuracy, calibrate sprayer before each use. x For information on spray equipment and calibration, consult spray equipment manufacturers and/or state recommendations. x All application equipment must be properly maintained and calibrated using appropriate carriers.

4.3 Application Volume and Spray Coverage x Good coverage, without runoff or leaching, of the pre-infection area (root zone, root ball, crown, etc.) is necessary for satisfactory control. x In situations where water volumes used are much less than 100 gallons and the area treated is small, the following table provides the Plentrix rates to make small

Plentrix 12 quantities of solution. Refer to the plant type for the correct amount of product to use when utilizing this table. o For soil drench, apply the application solution to the soil surface to wet the root area of the plants as listed in Section 6.1.

Amount of Plentrix to add to water to make the following quantities Rate of Plentrix (fl oz) 10 gallons 25 gallons 0.5 1.5 ml / 0.25 tsp 3.8 ml / 0.75 tsp 1.0 3 ml / 0.5 tsp 7.6 ml / 1.5 tsp 2.0 6 ml / 1 tsp 15 ml / 3 tsp / 1 Tbsp 3.0 9 ml / 2 tsp 22.6 ml / 4.5 tsp 4.0 12 ml / 3 tsp 30 ml / 6 tsp / 2 Tbsp

4.4 Mixing Directions x Thoroughly clean spray equipment before using this product. x Prepare no more spray mixture than is required for the immediate operation. x Agitate the spray solution before and during application. x Rinse spray tank thoroughly with clean water after each day’s use and dispose of pesticide rinsate by application to an already treated area. x Avoid allowing the spray mixture to stand overnight or for prolonged periods of time without agitation. Delayed application may cause product to settle and be difficult to re-suspend. If this occurs, good agitation is required for a minimum of 15 minutes before and during spray operation.

4.4.1 PLENTRIX ALONE x Add ½-Ҁ of the required amount of water to the spray or mixing tank. x With the agitator running, add Plentrix to the tank. x Continue agitation while adding the remainder of the water. x Begin application of the spray solution after Plentrix has completely dispersed into the mix water. x Maintain agitation until all of the mixture has been sprayed.

4.4.2 TANK-MIX PRECAUTIONS x When using an adjuvant or tank-mix partner, the user should conduct small-scale testing at the specified rates to ensure plant safety prior to broad scale commercial use. x Restriction: Do not mix with any product that prohibits such mixing x Observe all directions for use, crop/sites, use rates, dilution ratios, precautions, and limitations that appear on the tank-mix product label. x Restriction: Do not exceed any labeled use rate. x Follow the most restrictive label precautions and limitations.

Plentrix 13 It is the pesticide user's responsibility to ensure that all products are registered for the intended use. Read and follow the applicable restrictions and limitations and directions for use on all product labels involved in the tank mixing. Users must follow the most restrictive directions for use and precautionary statements of each product in the tank mixture

4.4.3 TANK-MIX COMPATIBILITY

A jar compatibility test is recommended prior to tank-mixing with other pesticides and/or adjuvants, in order to ensure the compatibility of Plentrix with other tank-mixed pesticide, adjuvant or fertilizer partners. The recommended procedure for conducting jar tank-mix compatibility tests is as follows:

Compatibility Test: Always conduct a tank-mix compatibility test when mixing with new or unknown tank-mix partners before use. The following test assumes a spray volume of 25 gal/A. For other spray volumes, make appropriate changes in the components. Check tank-mix compatibility using this procedure:

1. Add 1 pt of carrier (i.e., water) to be used in the spray operation to each of two clear 1-qt jars with tight lids.

2. To one of the jars, add ¼ tsp or 1.2 milliliters of a commercially available tank- mix compatibility agent approved for this use (¼ tsp is equivalent to 2 pt/100 gallons spray). Close and seal the lid, Invert the jar, shake, or stir gently to ensure thorough mixing.

3. To both jars, add the proportionate amount of each tank-mix partner. If more than one tank-mix partner is to be used, follow the recommended mixing order listed in Section 4.4.4 by adding dry formulations (wettable powders or water dispersible granules) first, followed by liquid flowables, capsule suspensions, emulsifiable concentrates and finally add adjuvants. After each addition, invert the jar, shake or stir gently to thoroughly mix. The appropriate amount of each tank-mix partner for this test, is as follows:

4. After adding all ingredients, put lids on and seal the lids, Invert each jar 10 times to fully mix. Let the mixtures stand for 15-30 minutes and then assess by looking for separation, large flakes, precipitates, gels, heavy oily film on the jar, or other signs of incompatibility. Determine if a compatibility agent is needed in the application mixture by comparing the 2 jars. If either mixture separates, but can be remixed readily, the mixture can be sprayed as long as good agitation is used. If the mixtures are incompatible, test the following methods of improving compatibility: (A) Slurry dry formulations in water before adding to the jar, or (B) add the compatibility agent directly into liquid formulations, before addition to the jar. If these procedures are followed but incompatibility is still observed, do not use the tank mixture.

Plentrix 14 4.4.4 PLENTRIX IN TANK MIXTURES x Add ½- ҀRIWKHUHTXLUHGDPRXQWRIZDWHUWRWKHVSUD\RUPL[LQJWDQN x With the agitator running, add the tank-mix partner(s) in this order:

1. water-soluble packaging
2. wettable powders
3. wettable granules (dry flowables)
4. liquid flowables (such as Plentrix)
5. emulsifiable concentrates
6. surfactants/adjuvants. x Allow each product to completely dissolve and disperse into the mix water before adding the next product and continue agitation until all products are added. x Continue agitation while adding the remainder of the water to the spray tank. x Begin application of the mixture after all products have been completely dispersed into the application mixture. x Maintain agitation until all of the application mixture has been applied.

4.5 Application through Irrigation Systems (Chemigation) 4.5.1 APPLICATION DIRECTIONS FOR IRRIGATION SYSTEMS (CHEMIGATION) x Apply this product only through overhead, hand-held, micro-irrigation systems and motorized calibrated irrigation systems either alone or with other pesticides that are registered for application through irrigation systems. Do not apply this product through any other type of irrigation system. x Dilution ratios are typically 1:100 to 1:200. x Plant injury and/or poor disease control can result from non-uniform distribution of treated water. x If you have questions about calibration, you should contact State Extension Service specialists, equipment manufacturers, or other experts. x Do not connect an irrigation system (including greenhouse systems) used for pesticide application to a public water system, unless the pesticide label-prescribed safety devices for public water systems (Section 4.5.3) are in place. x A person knowledgeable of the chemigation system and responsible for its operation, or under the supervision of the responsible person, shall shut the system down and make necessary adjustments should the need arise.

4.5.2 OPERATING INSTRUCTIONS

1. The system must contain a functional check-valve, vacuum relief valve, and low pressure drain appropriately located on the irrigation pipeline to prevent water- source contamination from backflow.
2. The pesticide injection pipeline must contain a functional, automatic, quick-closing check-valve to prevent the flow of fluid back toward the injection pump.
3. The pesticide injection pipeline must also contain a functional, normally closed, solenoid-operated valve located on the intake side of the injection pump and connected to the system interlock to prevent fluid from being withdrawn from the supply tank when the irrigation system is either automatically or manually shut down.

Plentrix 15 4. The system must contain functional interlo cking controls to automatically shut off the pesticide injection pump when the water pump motor stops. 5. The irrigation line or water pump must in clude a functional pressure switch which will stop the water pump motor when the water pressure decreases to the point where pesticide distribution is adversely affected. 6. Systems must use a metering pump, such as a positive displacement injection pump (e.g., diaphragm pump), effectively designed and constructed of materials that are compatible with pesticides and capable of being fitted with a system interlock. 7. Do not apply when wind speed favors drift beyond the area intended for treatment.

4.5.3 SPECIFIC INSTRUCTIONS FOR PUBLIC WATER SYSTEMS

1. Public water system means a system for t he provision to the public of piped water for human consumption if such system has at least 15 service connections or regularly serves an average of at least 25 individuals daily at least 60 days out of the year.
2. Chemigation systems connected to public water systems must contain a functional, reduced-pressure zone, back-flow preventer (RPZ) or the functional equivalent in the water supply line upstream from the point of pesticide introduction. As an option to the RPZ, the water from the public water system should be discharged into a reservoir tank prior to pesticide introduction. There shall be a complete physical break (air gap) between the outlet end of the fill pipe and the top or overflow rim of the reservoir tank of at least twice the inside diameter of the fill pipe.
3. The pesticide injection pipeline must contain a functional, automatic, quick-closing check valve to prevent the flow of fluid back toward the injection pump.
4. The pesticide injection pipeline must contain a functional, normally closed, solenoid- operated valve located on the intake side of the injection pump and connected to the system interlock to prevent fluid from being withdrawn from the supply tank when the irrigation system is either automatically or manually shut down.
5. The system must contain functional interlo cking controls to automatically shut off the pesticide injection pump when the water pump motor stops, or, in cases where there is no water pump, when the water pressure decreases to the point where pesticide distribution is adversely affected.
6. Systems must use a metering pump, such as a positive displacement injection pump (e.g., diaphragm pump) effectively designed and constructed of materials that are compatible with pesticides and capable of being fitted with a system interlock.
7. Do not apply when wind speed favors drift beyond the area intended for treatment.

5.0 RESTRICTIONS AND PRECAUTIONS 5.1 Use Restrictions x DO NOT apply Plentrix by air. x DO NOT allow a drench application to leach through or spill out of the container during or after treatment. x DO NOT use spray equipment which has been previously used to spray Plentrix to spray apple trees. Even trace amounts can cause unacceptable phytotoxicity to certain apple and crabapple varieties.

Plentrix 16 x DO NOT apply Plentrix to certain crabapple or cherry trees (including flowering or ornamental varieties such as Yoshino) due to possible phytotoxicity. (See Section 5.1.1.) Tolerant crabapple varieties are listed in Section 3.0.1. x DO NOT apply Plentrix to the following plants:

5.1.1 ORNAMENTALS SENSITIVE TO PLENTRIX: Do not apply Plentrix to these species or varieties.

Common Name Botanical Name Apple Malus domestica Crabapple - Flame variety Malus spp. Crabapple - Brandywine variety Malus spp. Crabapple - Novamac variety Malus spp. Cherry, Flowering - Yoshina variety Prunus yedoensis. Leatherleaf Fern Rumohra adianformis and other species

5.2 Use Precautions x Applications to Ligustrum spp. and Sygonium spp. may cause stunting or chlorosis. Responses may vary depending on environmental conditions. Test Plentrix on a limited area to evaluate for any possible damage before proceeding with treatment of the entire crop. x If pathogen isolates that are resistant to Group 4 and Group 11 fungicides are present, efficacy may be reduced for certain diseases. x The higher rates in the rate range (when a rate range is listed) may be required under conditions of heavy infection pressure, for highly susceptible varieties, or when environmental conditions conducive to disease exist.

5.3 Spray Drift Management

MANDATORY SPRAY DRIFT

Groundboom Applications: x User must only apply with the release height recommended by the manufacturer, but no more than 4 ft above the ground or crop canopy. x Applicators are required to use a medium or coarser droplet size in accordance with the most current version of the American Society of Agricultural and Biological Engineers Standard 572 (ASAE S572). x Do not apply when wind speeds exceed 15 mph at the application site. x Do not apply during temperature inversions.

Plentrix 17 SPRAY DRIFT ADVISORIES

THE APPLICATOR IS RESPONSIBLE FOR AVOIDING OFF-SITE SPRAY DRIFT. BE AWARE OF NEARBY NON-TARGET SITES AND ENVIRONMENTAL CONDITIONS.

IMPORTANCE OF DROPLET SIZE An effective way to reduce spray drift is to apply large droplets. Use the largest droplets that provide target pest control. While applying larger droplets will reduce spray drift, the potential for drift will be greater if applications are made improperly or under unfavorable environmental conditions.

Controlling Droplet Size – Ground Boom x Volume – Increasing the spray volume so that larger droplets are produced will reduce spray drift. Use the highest practical spray volume for the application. If a greater spray volume is needed, consider using a nozzle with a higher flow rate. x Pressure – Use the lowest spray pressure recommended for the nozzle to produce the target spray volume and droplet size. x Spray Nozzle – Use a spray nozzle that is designed for the intended application. Consider using nozzles designed to reduce drift.

BOOM HEIGHT – Ground Boom Use the lowest boom height that is compatible with the spray nozzles that will provide uniform coverage. For ground equipment, the boom should remain level with the crop and have minimal bounce.

SHIELDED SPRAYERS Shielding the boom or individual nozzles can reduce spray drift. Consider using shielded sprayers. Verify that the shields are not interfering with the uniform deposition of the spray on the target area.

TEMPERATURE AND HUMIDITY When making applications in hot and dry conditions, use larger droplets to reduce effects of evaporation.

TEMPERATURE INVERSIONS Drift potential is high during a temperature inversion. Temperature inversions are characterized by increasing temperature with altitude and are common on nights with limited cloud cover and light to no wind. The presence of an inversion can be indicated by ground fog or by the movement of smoke from a ground source or an aircraft smoke generator. Smoke that layers and moves laterally in a concentrated cloud (under low wind conditions) indicates an inversion, while smoke that moves upward and rapidly dissipates indicates good vertical air mixing. Avoid applications during temperature inversions.

Plentrix 18 WIND Drift potential generally increases with wind speed. AVOID APPLICATIONS DURING GUSTY WIND CONDITIONS. Applicators need to be familiar with local wind patterns and terrain that could affect spray drift.

6.0 ORNAMENTAL USE DIRECTIONS 6.1 Ornamentals – Soil Diseases (Container-Grown Plants) FOLIAGE PLANTS (EXCEPT PHILODRENDRON AND POTHOS) Target Disease Use Rate Application Timing Use Directions Fusarium Root/Stem Rot (Fusarium spp.) Phytophthora Root/Crown Rot (Phytophthora spp.) Pythium Root and Stem Rot (Pythium spp.) Rhizoctonia Root/Stem Rot (Rhizoctonia solani) Southern Blight (Sclerotium rolfsii) Mix 0.5 – 1.3 fl oz per 100 gallons.

Apply 1.5 – 2.0 pt of drench solution per sq ft of surface area.

Apply as a drench at planting and during production. Apply sufficient drench solution to thoroughly wet the root zone of the plants without leaching through the container. FOLIAGE PLANTS – PHILODENDRON Target Disease Use Rate Application Timing Use Directions Fusarium Root/Stem Rot (Fusarium spp.) Phytophthora Root/Crown Rot (Phytophthora spp.) Pythium Root and Stem Rot (Pythium spp.) Rhizoctonia Root/Stem Rot (Rhizoctonia solani) Southern Blight (Sclerotium rolfsii) Mix 1.5 – 2.0 fl oz per 100 gallons.

Apply 1.5 – 2.0 pt of drench solution per sq ft of surface area.

Apply as a drench at planting and during production. Apply sufficient drench solution to thoroughly wet the root zone of the plants without leaching through the container.

Reapply after 4 weeks if needed. FOLIAGE PLANTS – POTHOS Target Disease Use Rate Application Timing Use Directions Fusarium Root/Stem Rot (Fusarium spp.) Phytophthora Root/Crown Rot (Phytophthora spp.) Pythium Root and Stem Rot (Pythium spp.) Rhizoctonia Root/Stem Rot (Rhizoctonia solani) Southern Blight (Sclerotium rolfsii) Mix 0.5 fl oz per 100 gallons.

Apply 1.5 – 2.0 pt of drench solution per sq ft of surface area.

Apply as a drench at planting and during production. Apply sufficient drench solution to thoroughly wet the root zone of the plants without leaching through the container.

Reapply after 3 months if needed. HERBACEOUS PLANTS, FLOWERING PLANTS, FLOWERS GROWN FOR SEED, GROUND COVERS, ORNAMENTAL GRASSES AND SUCCULENTS Target Disease Use Rate Application Timing Use Directions

Plentrix 19 Fusarium Root/Stem Rot (Fusarium spp.) Phytophthora Root/Crown Rot (Phytophthora spp.) Pythium Root and Stem Rot (Pythium spp.) Rhizoctonia Root/Stem Rot (Rhizoctonia solani) Southern Blight (Sclerotium rolfsii) Mix 0.5 fl oz per 100 gallons.

Apply 1 pt drench solution per sq ft of surface area. Apply as a drench at seeding or to young seedlings or liners. Make a single drench application, applying sufficient drench solution to thoroughly wet the root zone of the plants without leaching through the container. Mix 1.0 – 2.0 fl oz per 100 gallons.

Apply 1.0 – 2.0 pt of drench solution per sq ft of surface area. Apply as a drench at planting and during production. Apply sufficient drench solution to thoroughly wet the root zone of the plants without leaching through the container.

Reapply after 4 weeks if needed. Mix 0.25 fl oz/cu yd of media Mix into growing media prior to transplanting. Dilute Plentrix into a sufficient quantity of water which allows thorough mixing of Plentrix into growing media. Downy mildew (such as: Peronospora spp. Plasmopara spp. Bremiella spp. Bremia spp.) Mix 1.0 – 2.0 fl oz per 100 gallons.

Apply 1.0 – 2.0 pt of drench solution per sq ft of surface area. Apply as a drench at planting and during production. Apply sufficient drench solution to thoroughly wet the root zone of the plants without leaching through the container.

Reapply after 4 weeks if needed. Suppression Powdery mildew Rust Mix 1.3 – 2.0 fl oz per 100 gallons.

Apply 1.0 – 2.0 pt of drench solution per sq ft of surface area. Apply as a drench at planting and during production. Apply sufficient drench solution to thoroughly wet the root zone of the plants without leaching through the container.

Reapply after 4 weeks if needed. POT AND BEDDING PLANTS (ANNUALS AND PERENNIALS); BULB, CORM AND TUBER CROPS (EXCEPT EASTER LILY); BREEDING CROPS AND CUT FLOWERS Target Disease Use Rate Application Timing Use Directions Fusarium Root/Stem Rot (Fusarium spp.) Phytophthora Root/Crown Rot (Phytophthora spp.) Pythium Root and Stem Rot (Pythium spp.) Rhizoctonia Root/Stem Rot (Rhizoctonia solani) Southern Blight (Sclerotium rolfsii)

Mix 0.5 fl oz per 100 gallons.

Apply 1 pt of drench solution per sq ft of surface area. Apply as a drench at seeding or to young seedlings or liners. Make a single drench application, applying sufficient drench solution to thoroughly wet the root zone of the plants without leaching through the container. Apply 2.0 fl oz/1,000 sq ft Apply as a soil surface spray after transplanting. Apply as a broadcast or banded spray to the surface of planting media in sufficient water to reach the root zone. Irrigate with ½ inch of water within 24 hours. Mix 1.0 – 2.0 fl oz per 100 gallons.

Apply 1 - 2 pt of drench solution per sq ft of surface area. Apply as a drench at transplanting.

Apply sufficient drench solution to thoroughly wet the root zone of the plants without leaching through the container.

Reapply drench after 4 weeks if needed. Mix 0.25 fl oz/cu yd of media Mix into growing media prior to transplanting. Dilute Plentrix into a sufficient quantity of water which allows thorough mixing of Plentrix into growing media. Downy mildew (such as: Peronospora spp. Plasmopara spp. Mix 0.5 fl oz per 100 gallons.

Apply as a drench at seeding or to young seedlings or liners. Make a single drench application.

Apply sufficient drench solution to thoroughly wet the root zone of the

Plentrix 20 Bremiella spp. Bremia spp.)

Apply 1 pt of drench solution per sq ft of surface area. plants without leaching through the container. Mix 0.5 fl oz per 100 gallons.

Apply 1 pt of drench solution per sq ft of surface area. Apply as a drench at transplanting. Apply sufficient drench solution to thoroughly wet the root zone of the plants without leaching through the container.

Reapply drench after 4 weeks if needed. BULB CROPS – EASTER LILY Target Disease Use Rate Application Timing Use Directions Fusarium Root/Stem Rot (Fusarium spp.) Phytophthora Root/Crown Rot (Phytophthora spp.) Pythium Root and Stem Rot (Pythium spp.) Rhizoctonia Root/Stem Rot (Rhizoctonia solani) Southern Blight (Sclerotium rolfsii) Mix 1.3 – 2.5 fl oz per 100 gallons.

Apply 1.5 – 2 pt of drench solution per sq ft of surface area. Apply as a drench at planting. Make a single drench application.

Apply sufficient drench solution to thoroughly wet the root zone of the plants without leaching through the container. WOODY ORNAMENTALS (EXCEPT AZALEA) AND NON-BEARING FRUIT, NUTS, AND VINES Ornamental trees and shrubs Evergreens (including conifers) Non-bearing fruit trees and plants Non-bearing nut trees Non-bearing vines Palms Target Disease Use Rate Application Timing Use Directions Fusarium Root/Stem Rot (Fusarium spp.) Phytophthora Root/Crown Rot (Phytophthora spp.) Pythium Root and Stem Rot (Pythium spp.) Rhizoctonia Root/Stem Rot (Rhizoctonia solani) Southern Blight (Sclerotium rolfsii) Mix 2.0 – 2.75 fl oz per 100 gallons.

Apply 1.5 – 2 pt of drench solution per sq ft of surface area. Apply as a drench at planting and during production.

Apply sufficient drench solution to thoroughly wet the root zone of the plants without leaching through the container.

Reapply after 2 - 4 months if needed. WOODY ORNAMENTALS – AZALEA Target Disease Use Rate Application Timing Use Directions Fusarium Root/Stem Rot (Fusarium spp.) Pythium Root and Stem Rot (Pythium spp.) Phytophthora Root/Crown Rot (Phytophthora spp.) Rhizoctonia Root/Stem Rot (Rhizoctonia solani) Southern Blight (Sclerotium rolfsii) Mix 1.3 – 2.5 fl oz per 100 gallons.

Apply 1.5 – 2 pt of drench solution per sq ft of surface area. Apply as a drench at planting and during production. Apply sufficient drench solution to thoroughly wet the root zone of the plants without leaching through the container.

Reapply drench after 2 to 4 months if needed. Apply 2.0 fl oz/1,000 sq ft Apply as a soil surface spray after transplanting. Apply as a broadcast or banded spray to the surface of planting media in sufficient water to reach the root zone. Irrigate with ½ inch of water within 24 hours. USE RESTRICTIONS

Plentrix 21

1. Maximum Single Application Rate (Plants Grown Outdoors and Indoors): 26.2 fl oz/A/application (equal to 0.55 lb azoxystrobin and 0.21 lb mefenoxam per acre)
2. Minimum Application Interval: 4 weeks for those ornamentals where re-application may be applied; a minimum of 3 months for Pothos
3. Maximum Annual Rate (Crops Grown Outdoors): 238.8 fl oz/A/year a. Do not apply more than 5.0 lb ai/A/year of azoxystrobin-containing products. b. Do not apply more than 6.0 lb ai/A/year of mefenoxam-containing products.
4. Maximum Annual Rate (Crops Grown Indoors): 238.8 fl oz/A/crop a. Do not apply more than 5.0 lb ai/A/crop of azoxystrobin-containing products. b. Do not apply more than 6.0 lb ai/A/crop of mefanoxam-containing products.

6.2 Ornamentals - Soil Diseases (Plants Grown in Ground) Target Pathogen Use Rate (fl oz/1,000 row feet) Application Timing Use Directions Fusarium spp. Pythium spp. Phytophthora spp. Rhizoctonia solani Sclerotium rolfsii

0.5 fl oz/ 1000 row ft Apply at planting in furrow or banded before the propagated units (seed, seed pieces, bulbs, or corms) are covered by soil. Apply product as an in- furrow or banded application in 3-15 gallons of water per 1,000 row- feet.

Mount the spray nozzle to allow the spray mixture to be applied directly into the furrow.

See Section 4.1.5 for additional information about banded applications. USE RESTRICTIONS

1. Maximum Single Application Rate: 26.2 fl oz/A/application (equal to 0.55 lb azoxystrobin and 0.21 lb mefenoxam per acre) [Note: Maximum single application rate is calculated based on 10” row spacing.]
2. Maximum Annual Rate: 238.8 fl oz/A/year a. Do not apply more than 5.0 lb ai/A/year of azoxystrobin-containing products. b. Do not apply more than 6.0 lb ai/A/year of mefenoxam-containing products.

Plentrix 22

6.3 Ornamentals – Foliar, Crown and Stem Diseases HERBACEOUS ORNAMENTALS Breeding crops Bulb crops (including Calla Lilies, Easter Lilies, Gladiolas and Caladiums) Cut flowers Flowering plants Flowers grown for seed Foliage Plants Ground covers

Ornamental Grasses Pot and bedding plants (annual and perennials) Succulents Target Disease Use Rate Application Timing Use Directions Aerial Blight (Rhizoctonia solani) Downy mildew (such as: Peronospora spp. Plasmopara spp., Bremiella spp. Bremia spp.) Phytophthora spp. (including P. ramorum) 1.0 fl oz per 100 gallons Apply to young seedlings or liners. Spray seedlings or liners thoroughly to ensure good coverage. 1.0 – 2.0 fl oz per 100 gallons

Apply to transplants or established plants during production. Spray plants thoroughly to ensure good coverage.

Apply prior to disease development or at the first indication of disease. WOODY ORNAMENTALS Evergreens (including conifers) Non-bearing fruit trees Non-bearing nut trees Non-bearing vines Ornamental tree and shrubs

Palms Succulents Target Disease Use Rate Application Timing Use Directions Aerial Blight (Rhizoctonia solani) Downy mildew (such as: Peronospora spp. Plasmopara spp., Bremiella spp. Bremia spp.) Phytophthora spp. (including P. ramorum) 2.0 – 2.75 fl oz per 100 gallons Apply to transplants or established plants during production. Spray plants thoroughly to ensure good coverage.

Apply prior to disease development or at the first indication of disease.

USE RESTRICTIONS

1. Maximum Single Application Rate (Plants Grown Outdoors and Indoors): 26.2 fl oz/A/application (equal to 0.55 lb azoxystrobin and 0.21 lb mefenoxam per acre)
2. Minimum Application Interval: 4 weeks for those ornamentals where re-application may be applied; a minimum of 3 months for Pothos
3. Maximum Annual Rate (Crops Grown Outdoors): 238.8 fl oz/A/year a. Do not apply more than 5.0 lb ai/A/year of azoxystrobin-containing products. b. Do not apply more than 6.0 lb ai/A/year of mefenoxam-containing products.
4. Maximum Annual Rate (Crops Grown Indoors): 238.8 fl oz/A/crop a. Do not apply more than 5.0 lb ai/A/crop of azoxystrobin-containing products. b. Do not apply more than 6.0 lb ai/A/crop of mefenoxam-containing products.
5. Maximum application rates for the following foliar applications with liquid products applied by groundboom or chemigation are not to exceed: a. Field-grown or nursery ornamentals – 0.75 lb ai/A.
6. Maximum application rate for products applied with handheld equipment for foliar applications are not to exceed: a. Nursery ornamentals, broadcast applications - 0.0025 lb ai/gal. b. Landscaping (plants, flowers trees, turf) - 0.0025 lb ai/gal.
7. Maximum application rates for products applied with mechanically pressurized handwand with liquid products are not to exceed: a. Greenhouse Ornamentals – 0.0025 lb ai/gal.

Plentrix 23 7.0 CONIFER USE DIRECTIONS 7.1 Conifers in Nurseries Target Disease Use Rate Application Timing Use Directions Phytophthora root and stem diseases 2.5 pt/A or 0.9 fl oz/1000 sq ft Apply to seedbeds and plug-plantings in the spring and again in the fall. Apply as a soil surface spray in at least 50 gallons of water per acre.

For best efficacy, ½ inch irrigation or rainfall is required within 24 hours after application. 5 pt/A or 1.8 fl oz/1000 sq ft

Apply to 2-0 transplants in the spring and again in the fall. Phytophthora foliar diseases 2.0 fl oz/100 gallons Apply to seedbeds and plug-plantings. Apply as a foliar spray until runoff.

For best efficacy, ½ inch irrigation or rainfall is required within 24 hours after application. 2.0 – 2.75 fl oz/100 gallons Apply to 2-0 transplants. USE RESTRICTIONS

1. Maximum Single Application Rate (Plants Grown Outdoors and Indoors): 11.9 fl oz/A/application (equal to 0.25 lb azoxystrobin and 0.11 lb mefenoxam per acre)
2. Minimum Application Interval: 4 weeks
3. Maximum Annual Rate (Crops Grown Outdoors): 95.5 fl oz/A/year a. Do not apply more than 2.0 lb ai/A/year of azoxystrobin-containing products. b. Do not apply more than 6.0 lb ai/A/year of mefenoxam-containing products.
4. Maximum Annual Rate (Crops Grown Indoors): 95.5 fl oz/A/crop a. Do not apply more than 2.0 lb ai/A/crop of azoxystrobin-containing products. b. Do not apply more than 6.0 lb ai/A/crop of mefenoxam-containing products.

Plentrix 24

7.2 Conifers in Plantations and Forestry Production Target Disease Use Rate Application Timing Use Directions Phytophthora root and stem diseases 1.3 – 2.5 pt/A Apply to transplants or established plants during production.

Applications should be made in early spring before growth starts and in the fall before the ground freezes. Apply as a directed soil spray in a minimum of 50 gallons of water, avoiding applications to the foliage.

If applications are banded, see Section 4.1.5 for information. Phytophthora foliar diseases, including those caused by Phytophthora ramorum 2.0 – 4.0 fl oz/100 gallons Apply to transplants or established plants during production. Apply as a foliar spray until runoff. Precautions: x Plentrix should be used in conjunction with good cultural practices. The use of Plentrix will not overcome poor management practices, such as planting on sites that are prone to flooding or are poorly drained. Plentrix fungicide will not revitalize trees showing moderate to severe disease symptoms. USE RESTRICTIONS

1. Maximum Single Application Rate: 11.9 fl oz/A/application (equal to 0.25 lb azoxystrobin and 0.11 lb mefenoxam per acre
2. Minimum Application Interval: 4 weeks
3. Maximum Annual Rate: 95.5 fl oz/A/year a. Do not apply more than 2.0 lb ai/A/year of azoxystrobin-containing products. b. Do not apply more than 6.0 lb ai/A/year of mefenoxam-containing products.
4. Maximum application rate for products applied with handheld equipment for foliar applications with liquid products are not to exceed: a. Christmas tree farm - 0.00125 lb ai/gal.

Plentrix 25

8.0 VEGETABLE PLANT USE DIRECTIONS 8.1 Brassica (Cole) Leafy Vegetables (Crop Group 5) and Turnip Greens Crops (including all cultivars, varieties, and/or hybrids of these) Broccoli Broccoli, Chinese (gai lon) Broccoli raab (rapini) Brussels sprouts Cabbage Cabbage, Chinese (bok choy) Cabbage, Chinese (Napa) Cabbage, Chinese mustard (gai choy) Cauliflower Cavalo broccolo Collards Kale Kohlrabi Mizuna Mustard Greens Mustard Spinach Rape Greens Turnip Greens (greens only) Target Disease Use Rate Application Timing Use Directions Pythium Damping-Off and Root Rots (Pythium spp.) Rhizoctonia Seedling Blight (Rhizoctonia solani) Seedling root rot, basal stem rot (Rhizoctonia solani) 12.0 fl oz/A or 0.25 fl oz/1,000 sq ft Apply after seeding.

Apply as a soil surface spray.

Irrigate lightly after application to move product into the root zone.

Downy Mildew (Peronospora parasitica) 2.0 – 4.0 fl oz/A or 1.5 – 3.0 ml/1000 sq ft

Apply when conditions are favorable for disease but before infection.

Apply as a foliar spray.

Plentrix must be used in a tank mix with other fungicides registered for control of downy mildew. Apply with the full labeled rate of the tank-mix partner fungicide. USE RESTRICTIONS

1. Maximum Single Application Rate (Plants Grown Indoors and Outdoors: 12.0 fl oz/A/application
2. Make only one application per crop.
3. Maximum Annual Rate: a) Do not apply greater than 12 fl oz/A (0.25 lb ai/A of azoxystrobin-containing and 0.10 lb ai/A of mefenoxam- containing products) to a single crop b) When multiple crops are produced in the same production area, do not apply greater than 0.75 lb ai/A/year of azoxystrobin-containing and 1.0 lb ai/A/year of mefenoxam-containing products
4. Pre-Harvest Interval (PHI): 21 days

Plentrix 26

8.2 Bulb Vegetables Bulb Vegetable Crops (including all cultivars, varieties, and/or hybrids of these) Dry Bulb Garlic Onions Shallots Green Onions Leeks Scallions Shallots, fresh leaves Green Onions (cont’d) Spring onions Welsh onions Target Disease Use Rate Application Timing Use Directions Pythium Damping-Off and Root Rots (Pythium spp.) Rhizoctonia Seedling Blight (Rhizoctonia solani) 12.0 fl oz/A or 0.28 fl oz/1,000 sq ft Apply after seeding and before plants are infected. Apply as a soil surface spray.

Irrigate lightly after application to move product into the root zone. USE RESTRICTIONS

1. Maximum Single Application Rate: 12.0 fl oz/A/application
2. Make only one application per crop.
3. Maximum Annual Rate: a. Do not apply greater than 12.0 fl oz/A (0.25 lb ai/A of azoxystrobin-containing and 0.10 lb ai/A of mefenoxam-containing products) to a single crop. b. When multiple crops are produced in the same producti on area, do not apply greater than 1.5 lb ai/A/year of azoxystrobin-containing and 1.0 lb ai/A/year of mefenoxam-containing products.
4. Pre-Harvest Interval (PHI): 7 days

Plentrix 27 8.3 Cucurbit Vegetables, Crop Group 9 Crops (including all cultivars, varieties, and/or hybrids of these) Chayote Chinese waxgourd Citron melon Cucumber Gherkin Gourd, edible Momordica spp. Balsam apple Balsam pear Bitter melon Chinese cucumber Muskmelon Cantaloupe Casaba Crenshaw melon Golden Pershaw melon Honeydew melon Honey balls Mango melon Persian melon Pineapple melon Santa Claus melon Muskmelon (cont’d) Snake melon True cantalouple Pumpkin Squash, summer Squash, winter Watermelon Target Disease Use Rate Application Timing Use Directions Pythium Damping-Off and Root Rots (Pythium spp.) Rhizoctonia Seedling Blight and Root Rot (Rhizoctonia solani) 14.8 fl oz/A or 0.34 fl oz/1,000 sq ft Apply after seeding and before plants are infected. Apply as a soil surface spray or as a soil treatment.

Irrigate lightly after application to move product into the root zone. USE RESTRICTIONS

1. Maximum Single Application Rate: 12.0 fl oz/A/application
2. Make only one application per crop.
3. Maximum Annual Rate: a) Do not apply greater than 12.0 fl oz/A (0.25 lb ai/A of azoxystrobin-containing and 0.10 lb ai/A of mefenoxam- containing products) to a single crop. b) When multiple crops are produced in the same production area, do not apply greater than 1.5 lb ai/A/year of azoxystrobin-containing and 1.0 lb ai/A/year of mefenoxam-containing products.
4. Pre-Harvest Interval (PHI): 7 days

Plentrix 28 8.4 Fruiting Vegetables (except Cucurbits) Crops (including all cultivars, varieties, and/or hybrids of these) African eggplant Eggplant Groundcherry Marynia Okra Pea eggplant Pepino Pepper, bell Pepper, chili Pepper, cooking Pepper, pimento Pepper, sweet Roselle Scarlet eggplant Tomatillo Target Disease Use Rate Application Timing Use Directions Crown Rot (Phytophthora capsici) Damping Off (Pythium spp.) Rhizoctonia seedling rot (Rhizoctonia solani) 1 pt/A or 0.37 fl oz/1,000 sq ft Apply after seeding and before plants are infected. Apply as a soil surface spray.

Irrigate lightly after application to move product into the root zone. Precautions: x May cause some yellowing of pepper leaves. x Plants already infected with Phytophthora cannot be cured with Plentrix. x The foliar blight phase of Phytophthora cannot be controlled with foliar applications of Plentrix. USE RESTRICTIONS

1. Maximum Single Application Rate: 12.0 fl oz/A/application
2. Make only one application per crop.
3. Maximum Annual Rate: a. Do not apply greater than 12 fl oz/A (0.25 lb ai/A of azoxystrobin- containing and 0.10 lb ai/A of mefenoxam-containing products) to a single crop. b. When multiple crops are produced in the same producti on area, do not apply greater than 1.0 lb ai/A/year of azoxystrobin-containing and 1.5 lb ai/A/year of mefenoxam-containing products.
4. Pre-Harvest Interval (PHI): 7 days

Plentrix 29 8.5 Herbs (Fresh and Dried) Crops (including all cultivars and varieties) Angelica Balm Basil Borage Burnet Catnip Chamomile Chervil (dried) Chinese Chive Chive Cilantro (leaf) Clary Coriander (leaf) Costmary Curry (leaf) Dillweed Horehound Hyssop Lavender Lemongrass Lovage (leaf) Marigold Marjoram Nasturtium Parsley (dried) Pennyroyal Rosemary Rue Sage Savory, Summer Savory, Winter Sweet Bay Tansy Tarragon Thyme Wintergreen Woodruff Wormwood Target Disease Use Rate Application Timing Use Directions Damping-Off (Pythium spp.) 12 fl oz /A or 0.28 fl oz/1000 sq ft Apply after seedling emergence and before plants Are infected. Apply as a soil surface spray directed to the base of the plants.

Irrigate lightly after application to move product into the root zone. Basil – Additional Diseased Controlled Basil Downy Mildew (Peronospora belbarhrii) 7.5 fl oz/5,000 sq ft Apply after seedling emergence and before plants are infected Apply as a spray to plug production trays in sufficient water to provide uniform coverage.

Irrigate lightly after application to move the product into growing media profile, but not to the point of leaching. USE RESTRICTIONS

1. Maximum Single Application Rate: 12.0 fl oz/A/application
2. Make only one application per crop.
3. Maximum Annual Rate: a. Do not apply greater than 12.0 fl oz/A (0.25 lb ai/A of azoxystrobin- containing and 0.10 lb ai/A of mefenoxam- containing products) to a single crop. b. When multiple crops are produced in the same producti on area, do not apply greater than 1.5 lb ai/A/year of azoxystrobin-containing and 1.0 lb ai/A/year of mefenoxam-containing products.
4. Pre-Harvest Interval (PHI): 21 days

Plentrix 30 8.6 Leafy Vegetables (except Brassica) Crops (including all cultivars, varieties, and/or hybrids of these) Amaranth Arugula Cardoon Celery Celtuce Chervil Chinese Celery Chrysanthemum (Edible-Leaved) Chrysanthemum (Garland) Corn Salad Cress (Garden) Cress (Upland) Dandelion Dock (Sorrel) Endive (Escarole) Fennel, Florence (Finochio) Lettuce (Head and Leaf) Orach Parsley Purslane (Garden) Purslane (Winter) Radicchio (Red Chicory) Rhubarb Spinach Spinach (New Zealand) Spinach (Vine) Swiss Chard Target Disease Use Rate Application Timing Use Directions Pythium Damping-Off and Root Rots (Pythium spp.)

Rhizoctonia Seedling Blight and Root Rot (Rhizoctonia solani)

Soilborne Diseases Web blight, Bottom rot, Crater rot, Root rot (Rhizoctonia solani) 12.0 fl oz/A or 0.28 fl oz/1,000 sq ft Apply after seeding and before plants are infected. Apply as a soil surface spray.

Irrigate lightly after application to move product into the root zone.

Lettuce (Head and Leaf) – Additional Diseased Controlled Downy Mildew (Bremia lactucae) 2.0 – 4.0 fl oz/A or 0.05 – 0.09 fl oz/1,000 sq ft Apply when conditions are favorable for disease. Apply as a foliar spray.

Plentrix must be used in a tank mix with other fungicides registered for control of downy mildew. Apply with the full label rate of the tank-mix partner fungicide. USE RESTRICTIONS

1. Maximum Single Application Rate (Plants Grown Indoors and Outdoors): 12.0 fl oz/A/application
2. Make only one application per crop.
3. Maximum Annual Rate: a. Do not apply greater than 12.0 fl oz/A (0.25 lb ai/A of azoxystrobin- containing and 0.10 lb ai/A of mefenoxam- containing products) to a single crop. b. When multiple crops are produced in the same producti on area, do not apply greater than 1.5 lb ai/A/year of azoxystrobin- containing and 1.0 lb ai/A/year of mefenoxam-containing products.
4. Pre-Harvest Interval (PHI): 7 days

Plentrix 31 8.7 Tomato Crops (including all cultivars and varieties) Tomato Target Disease Use Rate Application Timing Use Directions Root and Fruit Rot (Phytophthora spp.)

Pythium Damping-Off and Root Rots Pythium spp.) 4.7 fl oz/A or 0.11 fl oz/1,000 sq ft Apply after seeding and before plants are infected. Apply as a soil surface spray.

Irrigate lightly after application to move product into the root zone. USE RESTRICTIONS

1. Maximum Single Application Rate: 4.7 fl oz/A/application
2. Make only one application per crop.
3. Maximum Annual Rate: a. Do not apply greater than 4.7 fl oz/A (0.1 lb ai/A of azoxystrobin- containing and 0.04 lb ai/A of mefenoxam-containing products) to a single crop. b. When multiple crops are produced in the same producti on area, do not apply greater than 0.6 lb ai/A/year of azoxystrobin- containing and 1.5 lb ai/A/year of mefenoxam-containing products
4. Pre-Harvest Interval (PHI): 7 days

Plentrix 32 9.0 STORAGE AND DISPOSAL STORAGE AND DISPOSAL

Do not contaminate water, food, or feed by storage or disposal.

Pesticide Storage Store in original containers only. Store in a cool, dry place. Keep container closed when not in use. Do not store near food or feed. In case of spill on floor or paved surfaces, mop and remove to chemical waste storage area until proper disposal can be made if product cannot be used according to the label.

Pesticide Disposal Pesticide wastes may be hazardous. Improper disposal of excess pesticide, spray mixture, or rinsate is a violation of Federal law. If these wastes cannot be disposed of by use according to label instructions, contact your State Pesticide or Environmental Control Agency, or the Hazardous Waste representative at the nearest EPA Regional Office for guidance in proper disposal methods.

Container Handling [(less than or equal to 5 gallons)] Non-refillable container. Do not reuse or refill this container. Triple rinse container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank and drain for 10 seconds after the flow begins to drip. Fill the container ¼ full with water and recap. Shake for 10 seconds. Pour rinsate into application equipment or a mix tank or store rinsate for later use and disposal. Drain for 10 seconds after the flow begins to drip. Repeat this procedure two more times. Then offer for recycling if available or puncture and dispose of in a sanitary landfill, or by incineration, or by other procedures approved by state and local authorities.

Container Handling [(greater than 5 gallons)]

Non-refillable container. Do not reuse or refill this container. Triple rinse container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank. Fill the container ¼ full with water. Replace and tighten closures. Tip container on its side and roll it back and forth, ensuring at least one complete revolution, for 30 seconds. Stand the container on its end and tip it back and forth several times. Turn the container over onto its other end and tip it back and forth several times. Empty the rinsate into application equipment or a mix tank or store rinsate for later use or disposal. Repeat this procedure two more times. Then offer for recycling if available or puncture and dispose of in a sanitary landfill, or by incineration, or by other procedures approved by state and local authorities.

Container Handling [(greater than 5 gallons)]

Refillable container. Refill this container with pesticide only. Do not reuse this container for any other purpose. Cleaning the container before final disposal is the

Plentrix 33 responsibility of the person disposing of the container. Cleaning before refilling is the responsibility of the person refilling. To clean container before final disposal, empty the remaining contents from this container into application equipment or mix tank. Fill the container about 10 percent full with water. Agitate vigorously or recirculate water with the pump for 2 minutes. Pour or pump rinsate into application equipment or rinsate collection system. Repeat this rinsing procedure two more times. Then offer for recycling if available or puncture and dispose of in a sanitary landfill, or by incineration, or by other procedures approved by state and local authorities.

CONTAINER IS NOT SAFE FOR FOOD, FEED, OR DRINKING WATER.

Plentrix 34

10.0 CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY NOTICE: Read the entire Directions for Use and Conditions of Sale and Limitation of Warranty and Liability before buying or using this product. If the terms are not acceptable, return the product at once, unopened, and the purchase price will be refunded.

The Directions for Use of this product must be followed carefully. It is impossible to eliminate all risks inherently associated with the use of this product. Crop injury, ineffectiveness or other unintended consequences may result because of such factors as manner of use or application, weather or crop conditions, presence of other materials or other influencing factors in the use of the product, which are beyond the control of SYNGENTA CROP PROTECTION, LLC or Seller. To the extent permitted by applicable law, Buyer and User agree to hold SYNGENTA and Seller harmless for any claims relating to such factors.

SYNGENTA warrants that this product conforms to the chemical description on the label and is reasonably fit for the purposes stated in the Directions for Use, subject to the inherent risks referred to above, when used in accordance with directions under normal use conditions. To the extent permitted by applicable law: (1) this warranty does not extend to the use of this product contrary to label instructions or under conditions not reasonably foreseeable to or beyond the control of Seller or SYNGENTA, and (2) Buyer and User assume the risk of any such use. TO THE EXTENT PERMITTED BY APPLICABLE LAW, SYNGENTA MAKES NO WARRANTIES OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE NOR ANY OTHER EXPRESS OR IMPLIED WARRANTY EXCEPT AS WARRANTED BY THIS LABEL.

To the extent permitted by applicable law, in no event shall SYNGENTA be liable for any incidental, consequential or special damages resulting from the use or handling of this product. TO THE EXTENT PERMITTED BY APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE USER OR BUYER, AND THE EXCLUSIVE LIABILITY OF SYNGENTA AND SELLER FOR ANY AND ALL CLAIMS, LOSSES, INJURIES OR DAMAGES (INCLUDING CLAIMS BASED ON BREACH OF WARRANTY, CONTRACT, NEGLIGENCE, TORT, STRICT LIABILITY OR OTHERWISE) RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, SHALL BE THE RETURN OF THE PURCHASE PRICE OF THE PRODUCT OR, AT THE ELECTION OF SYNGENTA OR SELLER, THE REPLACEMENT OF THE PRODUCT.

SYNGENTA and Seller offer this product, and Buyer and User accept it, subject to the foregoing Conditions of Sale and Limitation of Warranty and Liability, which may not be modified except by written agreement signed by a duly authorized representative of SYNGENTA.

Plentrix 35

Plentrix™, the ALLIANCE FRAME, the SYNGENTA Logo and the PURPOSE ICON are Trademarks of a Syngenta Group Company

Viton™ is a trademark of The Chemours Company FC, LLC

©20XX Syngenta

For non-emergency (e.g., current product information), call Syngenta Crop Protection at 1-866-796-4368.

Manufactured for: Syngenta Crop Protection, LLC P.O. Box 18300 Greensboro, North Carolina 27419-8300

Plentrix 1596 MAS 0217 AMEND-C 0519-CL – jab-10/28/25 000100-01596.20190515C.PLENTRIX.AMEND.MAY2019-CL