crop-chem-docs/corpus/epa_ppls/264-989.md

TRIFLOXYSTROBIN FLOWABLE FUNGICIDE

• EPA Reg No: 264-989
• Registrant: BAYER CROPSCIENCE, LLC
• Signal word: Caution
• Active ingredients: Trifloxystrobin (22%)
• Label accepted: 2023-05-11
• Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000264-00989-20230511.pdf

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UNITED STATES ENVIRONMENTAL PROTECTION AGENCY WASHINGTON, DC 20460

OFFICE OF CHEMICAL SAFETY AND POLLUTION PREVENTION

May 11, 2023

Megan Mader Regulatory Affairs Manager, Fruits and Vegetables Bayer CropScience LP 800 N. Lindbergh Blvd. St. Louis, MO 63167

Subject: Registration Review Label Mitigation for Trifloxystrobin Product Name: TRIFLOXYSTROBIN FLOWABLE FUNGICIDE EPA Registration Number: 264-989 Application Date: July 12, 2022 Decision Number: 555162

Dear Megan Mader:

The Agency, in accordance with the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA), as amended, has completed reviewing all the information submitted with your application to support the Registration Review of the above referenced product in connection with the Trifloxystrobin Interim Decision, and has concluded that your submission is acceptable. The label referred to above, submitted in connection with registration under FIFRA, as amended, is acceptable.

Should you wish to add/retain a reference to the company’s website on your label, then please be aware that the website becomes labeling under the Federal Insecticide Fungicide and Rodenticide Act and is subject to review by the Agency. If the website is false or misleading, the product would be misbranded and unlawful to sell or distribute under FIFRA section 12(a)(1)(E). 40 CFR 156.10(a)(5) list examples of statements EPA may consider false or misleading. In addition, regardless of whether a website is referenced on your product’s label, claims made on the website may not substantially differ from those claims approved through the registration process. Therefore, should the Agency find or if it is brought to our attention that a website contains false or misleading statements or claims substantially differing from the EPA approved registration, the website will be referred to the EPA’s Office of Enforcement and Compliance.

A stamped copy of your labeling is enclosed for your records. This labeling supersedes all previously accepted labeling. You must submit one copy of the final printed labeling before you release the product for shipment with the new labeling. In accordance with 40 CFR 152.130(c), you may distribute or sell this product under the previously approved labeling for 12 months from the date of this letter. After 12 months, you may only distribute or sell this product if it bears this new revised labeling or subsequently approved labeling. “To distribute or sell” is defined under FIFRA section 2(gg) and its implementing regulation at 40 CFR 152.3.

Page 2 of 2 EPA Reg. No. 264-989 Decision No. 555162

If you have any questions about this letter, please contact DeMariah Koger by phone at (202)- 566-2288, or via email at koger.demariah@epa.gov.

S i n c e r e l y ,

       Linda Arrington, Branch Chief Risk Management and Implementation Branch 4 Pesticide Re-Evaluation Division Office of Pesticide Programs

Enclosure

1 TRIFLOXYSTROBIN Flowable Fungicide ACTIVE INGREDIENT: Trifloxystrobin..................................................................................................................................................................22% OTHER INGREDIENTS: ................................................................................................................................................78% TOTAL 100% Contains 2 pounds trifloxystrobin per gallon. EPA Reg. No. 264-989 EPA Est. KEEP OUT OF REACH OF CHILDREN CAUTION For MEDICAL And TRANSPORTATION Emergencies ONLY Call 24 Hours A Day 1-800-334-7577 For PRODUCT USE Information Call 1-866-99BAYER (1-866-992-2937) See [Back][Side] Panel for First Aid Instructions and [Leaflet][Booklet] for Complete Precautionary Statements and Directions for Use. (Note to reviewer : Location of additional precautionary statements, directions for use will vary between those listed, depending on container type/size.) FIRST AID IF IN EYES: x Hold eye open and rinse slowly and gently with water for 15-20 minutes. x Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye. x Call a poison control center or doctor for treatment advice. IF ON SKIN OR CLOTHING: x Take off contaminated clothing. x Rinse skin immediately with plenty of water for 15-20 minutes. x Call a poison control center or doctor for treatment advice. IF SWALLOWED: x Call a poison control center or doctor immediately for treatment advice. x Have person sip a glass of water if able to swallow. x Do not induce vomiting unless told to do so by a poison control center or doctor. x Do not give anything by mouth to an unconscious person. IF INHALED x Move person to fresh air. x If person is not breathing, call 911 or an ambulance, th en give artificial respiration, preferably mouth-to - mouth, if possible. x Call a poison control center or doctor for further treatment advice. In case of emergency call toll free the Bayer CropScience Emergency Response Telephone No. 1-800-334-7577. Have the product label with you when calling a poison control center or doctor, or going for treatment. TRIFLOXYSTROBIN GROUP 11 FUNGICIDE May 11, 2023 264-989

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PRECAUTIONARY STATEMENTS CAUTION HAZARDS TO HUMANS AND DOMESTIC ANIMALS Causes moderate eye irritation. Harmful if absorbed through skin. Prolonged or frequently repeated skin contact may cause allergic reactions in some individuals. Avoid contact with eyes, skin, or clothing. Wash thoroughly with soap and water after handling. PERSONAL PROTECTIVE EQUIPMENT (PPE) Applicators and other handlers must wear: x Long-sleeved shirt and long pants x Socks plus shoes x Waterproof gloves x Protective eyewear Engineering Controls: When handlers use closed systems in a manner that me ets the requirements listed in the Worker Protection Standard (WPS) for agricultural pesticides [40 CFR 170.607 (d)(e)(f) ], the handler PPE requirements may be reduced or modified as specified in the WPS. USER SAFETY RECOMMENDATIONS Users should: Wash hands before eating, drinking, chewing gum, using to bacco or using the toilet. Users should remove clothing immediately if pesticide gets inside. Then wash thoroughly and put on clean clothing. ENVIRONMENTAL HAZARDS This pesticide is toxic to fish and aquatic invertebrates. Applying this product when rain is not predicted for the next 24 hours will help reduce potential risk to aquatic invertebrates by reducing pesticide runoff from the treatment area into water bodies. Do not apply directly to water, or to areas where surface water is present or to intertidal areas below the mean high water mark. Do not contaminate water when disposing of equipment washwaters. Drift or run-off from treated areas is hazardous to fish and aquatic organisms in water adjacent to treated areas. Treated seed exposed on the soil surface may be hazardous to wildlife. Cover or collect seeds spilled during loading. DIRECTIONS FOR USE It is a violation of Federal law to use this product in a manner inconsistent with its labeling. Do not apply this product in a way that will contact workers or other persons, either directly or through drift. Only protected handlers may be in the area during application. Not for use on agricultural establishments in hopper-box, planter-box, slurry-box or other seed treatment applications at or immediately before planting. For any requirements specific to your State or Tribe, consult the agency respons ible for pesticide regulation. STORAGE AND DISPOSAL Do not contaminate water, food or feed by storage or disposal. PESTICIDE STORAGE Store in a cool, dry place and in such a manner as to prevent cross contamination with other pesticides, fertilizers, food, and feed. Store in original container and out of the reach of children, preferably in a locked storage area. Handle and open container in a manner as to prevent spillage. If container is leaking, invert to prevent leakage. If the container is leaking or material is spilled for any reason or cause, carefully dam up spilled material to prevent runoff. Refer to Precautionary Statements on label for hazards associated with the handling of this material. Do not walk through spilled material. Absorb spilled material with absorbing type compounds and dispose of as directed for pesticides below. In spill or leak incidents, keep unauthorized people away. You may contact the Bayer CropScience Emergency Response Team for decontamination procedures or any other assistance that may be necessary. The Bayer CropScience Emergency Response Telephone No. is 1-800-334-7577. PESTICIDE DISPOSAL Wastes resulting from the use of this product may be disposed of on site or at an approved waste disposal facility. CONTAINER DISPOSAL Rigid, Non-refillable containers small enough to shake (i.e., with capacities equal to or less than 5 gallons). Non-refillable container. Do not reuse or refill this container. Offer for recycling, if available. Triple rinse or pressure rinse container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank and drain for 10 seconds after the flow begins to drip. Fill the container ¼ full with water and recap. Shake for 10 seconds. Pour rinsate into application equipment or a mix tank or store rinsate for later use or disposal. Drain for 10 seconds after the flow begins to drip. Repeat this procedure two more times.

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Pressure rinse as follows: Empty the remaining contents into application equipment or a mix tank and continue to drain for 10 seconds after the flow begins to drip. Hold container upside down over application equipment or mix tank or collect rinsate for later use or disposal. Insert pressure rinsing nozzle in the side of the container, and rinse at about 40 PSI for at least 30 seconds. Drain for 10 seconds after the flow begins to drip.

Once container is rinsed, offer for recycling if available, or puncture and dispose of in a sanitary landfill.

Rigid Non-refillable containers that are too large to shake (i.e., with capacities greater than 5 gallons or 50 lbs) Non-refillable containers - Do not reuse or refill this container. After emptying product from container, either return container to Bayer CropScience per instructions from Bayer CropScience Customer Service Center (1-800-527-4781), or rinse and either recycle or dispose of the container as follows:

Bottom Discharge IBC (e.g. – Schuetz Caged IBC or Snyder Square Stackable) Pressure rinsing the container before final disposal is the responsibility of the person disposing of the container. To pressure rinse the container before final disposal, empty the remaining contents from the IBC into application equipment or mix tank. Raise the bottom of the IBC by 1.5 inches on the side which is opposite of the bottom discharge valve to promote more complete product removal. Completely remove the top lid of the IBC. Use water pressurized to at least 40 PSI to rinse all interior portions. Continuously pump or drain rinsate into application equipment or rinsate collection system while pressure rinsing. Continue pressure rinsing for 2 minutes or until rinsate becomes clear. Replace the lid and close bottom valve.

Top Discharge IBC, Drums, Kegs (e.g.– Snyder 120 Next Gen, Bonar B120, Drums, and Kegs). Triple rinsing the container before final disposal is the responsibility of the person disposing of the container. To triple rinse the container before final disposal, empty the remaining contents from this container into application equipment or mix tank. Fill the container at least 10 percent full with water. Agitate vigorously or recirculate water with the pump for 2 minutes. Rinse all interior surfaces. Pour or pump rinsate into application equipment or rinsate collection system. Repeat this procedure two more times.

Once container is rinsed, offer for recycling if available or puncture and dispose of in a sanitary landfill.

Refillable Containers Refillable container. Refill this container with pesticide only. Do not reuse this container for any other purpose. After emptying product from container, either return container to Bayer CropScience per instructions from Bayer CropScience Customer Service Center (1-800-527-4781) or rinse and either recycle or dispose of the container as follows:

Bottom Discharge IBC (e.g. – Schuetz Caged IBC or Snyder Square Stackable) Pressure rinsing the container before final disposal is the responsibility of the person disposing of the container. Cleaning before refilling is the responsibility of the refiller. To pressure rinse the container before final disposal, empty the remaining contents from the IBC into application equipment or mix tank. Raise the bottom of the IBC by 1.5 inches on the side which is opposite of the bottom discharge valve to promote more complete product removal. Completely remove the top lid of the IBC. Use water pressurized to at least 40 PSI to rinse all interior portions. Continuously pump or drain rinsate into application equipment or rinsate collection system while pressure rinsing. Continue pressure rinsing for 2 minutes or until rinsate becomes clear. Replace the lid and close bottom valve.

Top Discharge IBC, Drums, Kegs (e.g. – Snyder 120 Next Gen, Bonar B120, Drums, and Kegs). Triple rinsing the container before final disposal is the responsibility of the person disposing of the container. Cleaning before refilling is the responsibility of the refiller. To triple rinse the containers before final disposal, empty the remaining contents from this container into application equipment or mix tank. Fill the container at least 10 percent full with water. Agitate vigorously or recirculate water with the pump for 2 minutes. Rinse all interior surfaces. Pour or pump rinsate into application equipment or rinsate collection system. Repeat this procedure two more times.

Once container is rinsed, offer for recycling if available or puncture and dispose of in a sanitary landfill.

Refillable Containers End users are authorized to remove tamper evident cables as required to remove the product from the container unless the container is equipped with one way valves and refilling or returning is planned. If this is the case, end users are not authorized to remove tamper evident cables, one way valves or clean container. See Container Disposal instructions under Storage and Disposal.

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LABELING OF TREATED SEED Seed commercially treated with TRIFLOXYSTROBIN Flowable Fungicide must be labeled in accordance with all applicable requirements of the Federal Seed Act. All bags containing treated seed must be labeled or tagged as follows: x This seed has been treated with trifloxystrobin. x Do not use for feed, food or oil processing. x Store away from feeds and other foodstuffs. x When opening this bag or loading/pouring the treated seed, wear a long-sleeved shirt, long pants, shoes, socks, and chemical resistant gloves. After the seeds have been planted, do not enter or allow worker entry into treated areas during the restricted entry interval of 12 hours. Exception: Once the seeds are planted in so il or other planting media, the Worker Protection Standard all ows workers to enter the treated area without restriction if there will be no worker contact with the treated seeds in the soil or planting media.

FUNGICIDE RESISTANCE MANAGEMENT (FRAC) RECOMMENDATIONS For resistance management, please note that TRIFLOXYSTROBIN Fl owable Fungicide contains a Group 11 fungicide. Any fungal population may contain individuals naturally resistant to TRIFL OXYSTROBIN Flowable Fungicide and other Group 11 fungicides. A gradual or total loss of pest control may occur over time if thes e (fungicides) are used repeatedly in the same fields. Appropr iate resistance-management strategies should be followed. To delay fungicide resistance, take one or more of the following steps: x Adopt an integrated disease management program for fungicide use th at includes scouting, uses historical information related to pesticide use, and crop rotation, and which considers host plant resistance, impact of environmental conditions on disease development, disease thresholds, as well as cultural, biological and other chemical control practices. x Monitor treated fungal populations for resistance development. x Contact your local extension specialist or certified crop advi sor for any additional pesticide resistance-management and/or IPM recommendations for specific crops and pathogens. x For further information or to report suspected resistance contact Bayer CropScience at 1-866-99BAYER (1-866-992- 2937). You can also contact your pesticide distributor or university extension specialist to report resistance.

GENERAL INFORMATION TRIFLOXYSTROBIN Flowable Fungicide provides seed and seedling protection against seedborne fungi, Alternaria spp., Aspergillus spp, Cladosporium spp., and Penicillium spp. causing seed decay and soilborne pathogens, Rhizoctonia solani and Fusarium spp. Apply as a seed treatment using standard slurry or mist-type seed treatment equipment. Uniform application of seed is necessary to en sure seed safety and best disease protection. Seed should be sound and well cured prior to treatment. Product should be diluted with sufficient water to ensure complete seed coverage. Consult a seed treatment specialist regarding slurry rates recommended for the crop to be treated with TRIFLOXYSTROBIN Flowable Fungicide. The length of control will vary depending on the rate used.

USE RESTRICTION Do not use treated seed for food, feed, or oil processing.

USE PRECAUTION When using formulations that do not contain dye (like this pr oduct), to comply with 40 CFR 153.155, all seed treated with an ec onomic poison must be colored to distinguish it and prevent subsequent inadvertent use as a food for man or feed for animals. Alfalfa: Apply at a product rate of 0.96 fl oz per 100 lbs of seed. Canola, cotton, Cucurbit vegetable group, Fruiting vegetable group, Field corn, Mustardseed, Rapeseed, Popcorn, Rice, Sorghum, Sugar beet, Wheat, Potato (seed-piece), Peanut, Turf grass, Conifer, and Ornamental flowers: Apply at a product rate of 0.32 – 0.64 fl.oz. per 100 lbs. of seed. Soybean, Adzuki Bean, Asparagus Bean, Broad Bean (Succulent or Dry), Catjang Bean, Chinese Longbean, Field Bean, Guar Bean, Jackbean, Kidney Bean, Lablab Bean, Lima Bean (Succulent or Dry), Moth Bean, (Succulent or Dry), Mung Bean, Navy Bean, Pinto Bean, Rice Bean, Runner Bean, Snap Bean, Sword Bean, Tepary Bean, Urd Bean, Wax Bean, Yardlong Bean, Blackeyed Pea (Succulent or Dry), Chickpea, Cowpea (Succulent or Dry), Crowder Pea, Dwarf P ea, Edible-Pod Pea, English Pea, Field Pea, Garden Pea, Green Pea, Pigeon Pea (Succulent or Dry), Snow Pea, Southern Pea (Succ ulent or Dry), Sugar Snap Pea, Grain Lupin, Sweet Lupin, White Sweet Lupin, Lentil: Apply at a product rate of 0.32 fl. Oz. per 100 lbs. of seed. Sweet Corn: Apply at a product rate of 0.32 – 0.96 fl. Oz. per 100 lbs. of seed.

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Cotton For seed and seedling protection: apply Trifloxystrobin Flowable Fungicide as a seed treatment: Application Rates* Number of cottonseed per pound fl oz per 100 pounds of seed mg ai/ seed fl oz/ 100,000 unit of seed 3600 0.32 - 0.64 0.0063 - 0.0126 0.08 - 0.17 4400 0.32 - 0.64 0.0051 - 0.0103 0.07 - 0.14 5200 0.32 - 0.64 0.0044 - 0.0088 0.06 - 0.12 6000 0.32 - 0.64 0.0038 - 0.0076 0.05 - 0.10

• Do not apply more than 0.0013 lbs of active ingredient trifloxystrobin as a seed treatment per planted cotton acre

Field Corn For seed and seedling protection: apply Trifloxystrobin Flowable Fungicide as a seed treatment: Application Rates* Number of corn seed per pound fl oz per 100 pounds of seed mg ai/ seed fl oz/ 80,000 unit of seed 1200 0.32 - 0.64 0.0189 - 0.0378 0.213 - 0.426 1600 0.32 - 0.64 0.0142 - 0.0284 0.160 - 0.320 2000 0.32 - 0.64 0.0114 - 0.0227 0.128 - 0.256 2400 0.32 - 0.64 0.0095 - 0.0189 0.106 - 0.213

Soybean For seed and seedling protection: apply Trifloxystrobin Flowable Fungicide as a seed treatment: Application Rates* Number of soybean seed per pound fl oz per 100 pounds of seed mg ai/ seed fl oz / 140,000 unit of seed 2000 0.32 0.0114 0.224 2400 0.32 0.0095 0.187 2800 0.32 0.0081 0.160 3200 0.32 0.0071 0.140 3600 0.32 0.0063 0.124

• Do not apply more than 0.0027 lbs of active ingredient trifloxystrobin as a seed treatment per planted soybean acre

ROTATIONAL CROP RESTRICTION Areas planted with treated seed may be replanted immediately with any crop for which a tolerance exists for trifloxystrobin. Do not plant any crop without trifloxystrobin tolerances until 30 days after planting trifloxystrobin treated seed.

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IMPORTANT: READ BEFORE USE Read the entire Directions for Use, Conditions, Disclaimer of Warranties and Limitations of Liability before using this product. If terms are not acceptable, return the unopened product container at once. By using this product, user or buyer accepts the following Conditions, disclaimer of Warranties and Limitations of Liability. Treatment of highly mechanically damaged seed, or seed of known lo w vigor and poor quality, may result in reduced germination a nd/or reduction of seed and seedling vigor. Treat and conduct germination tests on a small portion of seed before committing the tota l seed lot to a selected chemical treatment. Due to seed quality conditions beyond the control of Bayer CropScience, no claims are made to guarantee germination of carry-over seed. CONDITIONS: The directions for use of this product are believed to be adequate and must be followed carefully. However, it is impossible to eliminate all risks associated with the use of this product. Crop injury, ineffectiveness or other unintended consequences m ay result because of such factors as weather conditions, presence of other materials, or the manner of use or application, all of which are beyond the control of Bayer CropScience LP. All such risks shall be assumed by the user or buyer. DISCLAIMER OF WARRANTIES: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER CROPSCIENCE LP MAKES NO OTHER WARRANTIES, EXPRESS OR IMPLIE D, OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE OR OTHERWISE, THAT EXTEND BEYOND THE STATEMENTS MADE ON THIS LABEL. No agent of Bayer CropScience LP is authorized to make any warranties beyond those contained herein or to modi fy the warranties contained herein. TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER CROPSCIENCE LP DISCLAIMS ANY LIABILITY WHATSOEVER FOR SPECIAL, INCIDENTAL OR CONSEQUENTIAL DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT. LIMITATIONS OF LIABILITY: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE USER OR BUYER FOR ANY AND ALL LOSSES, INJURIES OR DAMAG ES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, WHETHER IN CONTRACT, WARRANTY, TORT, NEGLIGENCE, STRICT LIABILITY OR OTHERWISE, SHALL NOT EXCEED THE PURCHASE PRICE PAID, OR AT BAYER CROPSCIENCE’S ELECTION, THE REPLACEMENT OF PRODUCT.

NET CONTENTS:

Produced for

Bayer CropScience LP 800 N. Lindbergh Blvd. St. Louis, MO 63167 1-866-99BAYER (1-866-992-2937)

TRIFLOXYSTROBIN FLOWABLE FUNGICIDE (PENDING) 09/09/2019, 09/10/2019, 07/12/2022, 04/18/2023