crop-chem-docs/corpus/epa_ppls/100-1648.md

Saltro

• EPA Reg No: 100-1648
• Registrant: SYNGENTA CROP PROTECTION, LLC
• Signal word: Caution
• Active ingredients: Pydiflumetofen (41.7%)
• Label accepted: 2025-07-24
• Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000100-01648-20250724.pdf

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July 24, 2025

Tammy Tyler Team Lead, Federal Regulatory Affairs Syngenta Crop Protection, LLC P.O. Box 18300 Greensboro, NC 27419

Subject: PRIA Label Amendment – a dding seed treatment use on potato Product Name: Saltro® EP A Registration Number: 100-1648 Application Da te: November 15, 2023 Case Number: 494707

Dear Tammy Tyler:

The application referred to above, submitted under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), as amended, is acceptable under FIFRA section 3(c)(5).

You must submit and/or cite all data required for registration/reregistration/registration review of your product when the Agency requires all registrants of similar products to submit such data.

A stamped copy of your labeling is enclosed for your records. This labeling supersedes all previously accepted labeling. You must submit one (1) copy of the final printed labeling before you release the product for shipment with the new labeling. In accordance with 40 CFR 152.130(c), you may distribute or sell this product under the previously approved labeling for 18 months from the date of this letter. After 18 months, you may only distribute or sell this product if it bears this new revised labeling or subsequently approved labeling. “To distribute or sell” is defined under FIFRA section 2(gg) and its implementing regulation at 40 CFR 152.3.

Should you wish to add/retain a reference to the company’s website on your label, then please be aware that the website becomes labeling under FIFRA and is subject to review by the Agency. If the website is false or misleading, the product would be misbranded and unlawful to sell or distribute under FIFRA section 12(a)(1)(E). 40 CFR 156.10(a)(5) lists examples of statements EPA may consider false or misleading. In addition, regardless of whether a website is referenced on your product’s label, claims made on the website may not substantially differ

Page 2 of 2 EPA Reg. No. 100-1648 Case No. 494707

from those claims approved through the registration process. Therefore, should the Agency find or if it is brought to our attention that a website contains false or misleading statements or claims substantially differing from the EPA approved registration, the website will be referred to the EPA’s Office of Enforcement and Compliance.

Your release for shipment of the product constitutes acceptance of these conditions. If these conditions are not complied with, the registration will be subject to cancellation in accordance with FIFRA section 6.

If you have any questions, please contact Elisha Graham at graham.elisha@epa.gov.

S i n c e r e l y ,

C y n t h i a L . G i l e s - P a r k e r , C h i e f F u n g i c i d e B r a n c h R e g i s t r a t i o n D i v i s i o n ( 7 5 0 5 T )

Enclosure -stamped “accepted” label

SUPPLEMENTAL LABELING

Syngenta Crop Protection, LLC P. O. Box 18300 Greensboro, North Carolina 27419-8300

SCP 1648-

PYDIFLUMETOFEN GROUP 7 FUNGICIDE

Saltro®

[Alternate Brand Name: Trebuset®]

Fungicide

ADEPIDYN® Technology*

This supplemental label expires on 07/22/2028 and must not be used or distributed after this date.

Active Ingredient: Pydiflumetofen** ................................ ................................ ................................ ................. 41.7% Other Ingredients: 58.3% Total: 100.0%

*Technology denotes the active ingredient Pydiflumetofen **CAS No. 1228284-64-7

Saltro is a flowable concentrate for seed treatment containing 4.17 lb pydiflumetofen per gallon.

KEEP OUT OF REACH OF CHILDREN.

CAUTION

EPA Reg. No. 100-1648

All applicable directions, restrictions, and precautions on the EPA -registered label are to be followed. Before using Saltro as permitted according to this supplemental label, read and follow all applicable directions, restrictions, and precautions on the EPA- registered label on or attached to the pesticide product container. This Supplemental Labeling contains revised use instructions and/or restrictions that may be different from those that appear on the container label. This Supplemental Labeling must be in the possession of the user at the time of pesticide application. It is a violation of federal law to use this product in a manner inconsistent with its labeling.

07/24/2025 100-1648

Saltro Page 2 DIRECTIONS FOR USE Seed Treatment Directions

Potato Crops [– Not Registered for Use by California] Potato Target Disease/Pest Use Rate fl oz/100 lb of seed mg ai/seed

Fusarium dry rot (Fusarium spp.) Seed-borne silver scurf (Helminthosporium solani)

Suppression only:-

Plant Parasitic Nematodes: Root Knot Nematode (Meloidogyne spp.) Lesion Nematode (Pratylenchus spp.) Stubby Root Nematode (Paratrichodorus spp.) Sting Nematode (Belonolaimus spp.)

0.039 – 0.062 0.71 – 1.13 USE INFORMATION • The mg ai/seed rate provided is based on an average seed weight of 8 potato seed tubers per pound. • Saltro requires dilution prior to atomization and application to potato seed tubers. • A volume of 2 - 4 fl oz of slurry mixture/100 lb of potato seed tubers is recommended. • For best results, calibrate the equipment so that every potato seed tuber is uniformly coated with a fine layer of the slurry mix, without any excess dripping out of the treated seed. Applying excess moisture may predispose the seed to rotting, resulting in poor emergence and stand. • Apply Saltro only in well-ventilated areas. • In high humidity, use drying fans on the treated potato seed pieces. If possible, allow treated tubers to dry during transit and plant the same day as treatment after potatoes have been cut. • Treated Seed Storage: If potato seed pieces must be stored before planting, consult your local Syngenta representative for information on best management practices for handling and storing treated seed potatoes, including the use of an EPA-approved dye or colorant that imparts an unnatural color (green or red is recommended) to the seed as stated in 40 CFR 153.155 (c). • If the treated potato seed tubers need to be stored or held for a few days, then make sure that the treated seed tubers are stored in well-ventilated areas that allow air to move through and out of the treated potato seed tubers. An ideal air temperature for storage is 60°F at a relative humidity of 85 - 90%. Avoid free moisture forming within or around the treated potato seed tubers during storage. Resistance Management: • Refer to Section 3.1. USE RESTRICTIONS • DO NOT exceed 0.33 lb ai/A/year of pydiflumetofen-containing products through any combination of seed and foliar applications. • Sections 4.0, 4.1, 5.0, and 6.0 contain additional product use restrictions. • DO NOT BAG POTATO SEED TUBERS THAT HAVE BEEN TREATED WITH A LIQUID SEED TREATMENT.

ADEPIDYN®, Saltro®, Trebuset®, and the Syngenta logo are trademarks of a Syngenta Group Company © 2025 Syngenta Saltro 1648 MAS 0223 SUPP-D 1123-CL – jeb – 07/22/2025 000100-01648.20231110D.SALTRO_SUPP_NOV2023-CL.pdf

[Master Label]

Saltro® [Alternate Brand Name: Trebuset®] Fungicide

ADEPIDYN® Technology*

Active Ingredient: Pydiflumetofen** ...................................................................................................... 41.7% Other Ingredients: 58.3% Total: 100.0%

*Technology denotes the active ingredient Pydiflumetofen **CAS No. 1228284-64-7

Saltro is a flowable concentrate for seed treatment containing 4.17 lb pydiflumetofen per gallon.

KEEP OUT OF REACH OF CHILDREN.

CAUTION

See additional precautionary statements and directions for use inside booklet.

EPA Reg. No. 100-1648

EPA Est.

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Net Contents

[Batch Code: _____ ] (For nonrefillables only.)

PYDIFLUMETOFEN GROUP 7 FUNGICIDE 07/24/2025 100-1648 07/24/2025 100-1648

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TABLE OF CONTENTS

1.0 FIRST AID 2.0 PRECAUTIONARY STATEMENTS 2.1 Hazards to Humans and Domestic Animals 2.2 Personal Protective Equipment (PPE) 2.2.1 User Safety Requirements 2.2.2 Engineering Controls 2.2.3 User Safety Recommendations 2.3 Environmental Hazards 2.3.1 Groundwater Advisory 2.3.2 Surface Water Advisory 2.4 Physical or Chemical Hazards DIRECTIONS FOR USE 3.0 PRODUCT INFORMATION 3.1 Resistance Management 4.0 APPLICATION DIRECTIONS 4.1 Mixing Directions 4.1.1 Tank-Mix Precautions 4.1.2 Tank Mixtures 5.0 RESTRICTIONS 6.0 SEED CONTAINER LABEL REQUIREMENTS 7.0 Seed Treatment Directions 7.1 Cereals, Small Grain 7.2 Corn 7.3 Cottonseed – Crop Subgroup 20C 7.4 Legume Vegetables (Succulent or Dried) – Crop Group 6 7.5 Peanut 7.6 Potato 7.7 Rapeseed (including Canola) – Crop Subgroup 20A 7.8 Sorghum 7.9 Soybean 8.0 STORAGE AND DISPOSAL 9.0 CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY

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1.0 FIRST AID FIRST AID If swallowed • Call a poison control center or doctor immediately for treatment advice. • Have person sip a glass of water if able to swallow. • Do not induce vomiting unless told to do so by a poison control center or doctor. • Do not give anything by mouth to an unconscious person. If inhaled • Move person to fresh air. • If person is not breathing, call 911 or an ambulance, then give artificial respiration, preferably mouth-to-mouth if possible. • Call a poison control center or doctor for treatment advice. If on skin or clothing • Take off contaminated clothing. • Rinse skin immediately with plenty of water for 15-20 minutes. • Call a poison control center or doctor for treatment advice. Have the product container or label with you when calling a poison control center or doctor, or going for treatment. SYNGENTA HOTLINE NUMBER For 24-Hour Medical Emergency Assistance (Human or Animal) Or Chemical Emergency Assistance (Spill, Leak, Fire or Accident) Call 1-800-888-8372

2.0 PRECAUTIONARY STATEMENTS 2.1 Hazards to Humans and Domestic Animals

CAUTION

Harmful if swallowed. Harmful if absorbed through skin. Harmful if inhaled. Avoid breathing vapor or spray mist. Avoid contact with skin, eyes or clothing. Wash thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco or using the toilet. Remove and wash contaminated clothing before reuse. 2.2 Personal Protective Equipment (PPE) Applicators and other handlers must wear: • Long-sleeved shirt and long pants • Chemical-resistant gloves: barrier laminate, butyl rubber ≥14 mils, neoprene rubber ≥14 mils, nitrile rubber ≥14 mils, polyvinyl chloride (PVC) ≥14 mils, or Viton™ ≥14 mils • Shoes plus socks

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2.2.1 User Safety Requirements Follow manufacturer’s instructions for cleaning/maintaining PPE. If no such instructions for washables exist, use detergent and hot water. Keep and wash PPE separately from other laundry. 2.2.2 Engineering Controls When handlers use closed systems, enclosed cabs, or aircraft in a manner that meets the requirements listed in the Worker Protection Standard (WPS) for agricultural pesticides (40 CFR 170.240(d)(4-6)), the handler PPE requirements may be reduced or modified as specified in the WPS. IMPORTANT: When reduced PPE is worn because a closed system is being used, handlers must be provided all PPE specified above for “applicators and other handlers” and have such PPE immediately available for use in an emergency, such as a spill or equipment breakdown. 2.2.3 User Safety Recommendations Users should: • Wash hands before eating, drinking, chewing gum, using tobacco, or using the toilet. • Remove clothing/PPE immediately if pesticide gets inside. Then wash thoroughly and put on clean clothing. • Remove PPE immediately after handling this product. Wash the outside of gloves before removing. As soon as possible, wash thoroughly and change into clean clothing.

2.3 Environmental Hazards Pydiflumetofen is toxic to wildlife, fish, aquatic invertebrates, and oysters and shrimp. Treated seeds exposed on the soil surface may be hazardous to wildlife. Cover or collect seeds spilled during loading and planting. Do not allow treated seed to remain uncovered on the soil surface. Drift and runoff may be hazardous to aquatic organisms in water adjacent to treated areas. Do not apply directly to water, or to areas where surface water is present, or to intertidal areas below the mean high-water mark. Do not contaminate water when disposing of equipment washwater or rinsate.

2.3.1 Groundwater Advisory This chemical has properties and characteristics associated with chemicals detected in groundwater. This chemical may leach into groundwater if used in areas where soils are permeable, particularly where the water table is shallow. 2.3.2 Surface Water Advisory This product may impact surface water quality due to runoff of rain water. This is especially true for poorly draining soils and soils with shallow groundwater. This product is classified as having a medium potential for reaching both surface water and aquatic sediment via runoff several months or more after application.

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A level, well-maintained vegetative buffer strip between areas to which this product is applied and surface water features such as ponds, streams, and springs will reduce the potential loading of pydiflumetofen from runoff water and sediment. Runoff of this product will be reduced by avoiding applications when rainfall or irrigation is expected to occur within 48 hours. Sound erosion control practices will reduce this product’s potential to reach aquatic sediment via runoff. 2.4 Physical or Chemical Hazards Do not mix or allow to come in contact with oxidizing agents. Hazardous chemical reaction may occur. DIRECTIONS FOR USE It is a violation of federal law to use this product in a manner inconsistent with its labeling. Listed crop uses include crops grown for seed. Do not apply this product in a way that will contact workers or other persons, either directly or through drift. Only protected handlers may be in the area during application. For any requirements specific to your state or tribe, consult the agency responsible for pesticide regulation. Notify state and/or federal authorities and Syngenta immediately if you observe any adverse environmental effects due to use of this product. FAILURE TO FOLLOW DIRECTIONS AND PRECAUTIONS ON THIS LABEL MAY RESULT IN CROP INJURY; POOR DISEASE CONTROL; AND/OR ILLEGAL RESIDUES. AGRICULTURAL USE REQUIREMENTS Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR Part 170. This Standard contains requirements for the protection of agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of agricultural pesticides. It contains requirements for training, decontamination, notification, and emergency assistance. It also contains specific instructions and exceptions pertaining to the statements on this label about personal protective equipment (PPE) and restricted-entry interval. The requirements in this box only apply to uses of this product that are covered by the Worker Protection Standard (WPS). Do not enter or allow worker entry into treated areas during the restricted-entry interval (REI) of 12 hours. Exception: If the seed is treated with the product and the treated seed is soil incorporated, the Worker Protection Standard, under certain circumstances, allows workers to enter the treated area if there will be no contact with anything that has been treated. PPE required for early entry to treated areas that is permitted under the Worker Protection Standard and that involves contact with anything that has been treated, such as plants, soil, or water is: • Coveralls • Chemical-resistant gloves: barrier laminate, butyl rubber ≥14 mils, nitrile rubber ≥14 mils, neoprene rubber ≥14 mils, polyvinyl chloride (PVC) ≥14 mils, or Viton ≥14 mils • Shoes plus socks

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Treatment of highly mechanically scarred or damaged seed or seed known to be of low vigor and poor quality may result in reduced germination and/or reduction of seed and seedling vigor. Treat a quantity of seed using equipment similar to that planned for treating the total seed lot. Then conduct germination tests with a portion of this treated seed before committing the total seed lot to a selected seed treatment. Due to seed quality, crop or variety sensitivity, and seed storage conditions beyond the control of Syngenta, no claims are made to guarantee the germination of seed or propagating material for any crop seed treated with Saltro.

3.0 PRODUCT INFORMATION Saltro is a seed treatment fungicide which provides protection from listed seed- and soil- borne diseases of corn (field, pop, seed, and sweet), cotton, legume vegetables (succulent or dried) crop group 6, peanut, potato, rapeseed (including canola) crop subgroup 20A, small grain cereals (barley, oats, rye, triticale, and wheat), sorghum, and soybean. Saltro is effective against seed and seedling blight or damping-off caused by listed seed- and soil- borne Fusarium spp., including Fusarium virguliforme, the causal organism of Sudden Death Syndrome (SDS) in soybean seed, soil-borne black leg (Leptosphaeria maculens) in canola, cotton root rot (Phymatotrichopsis omnivorum) in cotton (suppression only), Aspergillus crown rot (Aspergillus niger) in peanut (suppression only), and Fusarium dry rot caused by Fusarium spp. and Silver scurf caused by Helminthosporium solani in potato. Saltro also provides activity against listed plant parasitic nematodes. Where rate ranges are shown, use the higher rate when disease pressure is expected to be severe.

Read all label directions for use. All applications must be made according to the use directions that follow.

3.1 Resistance Management For resistance management, note that Saltro contains a Group 7 fungicide. Any fungal population may contain individuals naturally resistant to Saltro and other Group 7 fungicides. A gradual or total loss of pest control may occur over time if these fungicides are used repeatedly in the same fields. Appropriate resistance management strategies should be followed.

Pydiflumetofen belongs to the carboxamide class of chemistry and is a succinate dehydrogenase inhibitor (SDHI) which disrupts cellular respiration and energy generation.

To delay fungicide resistance, take one or more of the following steps:

• Rotate the use of Saltro or other Group 7 fungicides within a growing season sequence with different groups that control the same pathogens. • Use tank mixtures with fungicides from a different group that are equally effective on the target pest when such use is permitted. Use at least the minimum application rate as labeled by the manufacturer.

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• Adopt an integrated disease management program for fungicide use that includes scouting, uses historical information related to pesticide use and crop rotation, and considers host plant resistance, impact of environmental conditions on disease development, and disease thresholds, as well as cultural, biological and other chemical control practices. • Where possible, make use of predictive disease models to effectively time fungicide applications. Note that using predictive models alone is not sufficient to manage resistance. • Monitor treated fungal populations for resistance development. • Contact your local extension specialist or certified crop advisor for any additional pesticide resistance management and/or IPM recommendations for specific crops and pathogens. • For further information or to report suspected resistance contact Syngenta Crop Protection at 1-866-796-4368. You can also contact your university extension specialist to report resistance.

4.0 APPLICATION DIRECTIONS Apply Saltro as a water-based slurry utilizing standard seed treatment equipment which provides uniform seed coverage. Uneven or incomplete seed coverage may not give the desired level of disease control. This product must be used only by commercial seed treatment facilities or with commercial seed treatment equipment on farm subject to the Restrictions listed below and as specified for each crop in the crop specific use instructions on this label. Do not use in hopper-box, planter-box, slurry-box or other seed treatment applications at or immediately before planting.

4.1 Mixing Directions Thoroughly mix the specified amount of Saltro into the required amount of water and other seed treatment products for better application performance. Follow the manufacturer’s application instructions for the seed treatment equipment being used. It’s important to homogenize products prior to use and to maintain constant agitation of the slurry during the treatment. This product does not contain dye and treated seed is not covered by an appropriate tolerance, tolerance exemption, or other clearance under the Federal Food, Drug and Cosmetic Act. To comply with 40 CFR 153.155, therefore, all seed treated commercially with this product must be colored with an EPA-approved dye or colorant of a suitable color to prevent accidental use as food for man or feed for animals. The buyer of Saltro fungicide is responsible for ensuring all seed treated with this product is adequately dyed with a suitable color to prevent accidental use as food for man or feed for animals. Refer to 21 CFR Part 2.25. Allow seed to dry before bagging.

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4.1.1 Tank-Mix Precautions

It is the pesticide user’s responsibility to ensure that all products are registered for the intended use. Read and follow the applicable restrictions and limitations and directions for use on all product labels involved in tank mixing. Users must follow the most restrictive directions for use and precautionary statements of each product in the tank mixture.

4.1.2 Tank Mixtures

Cereals, Small Grain (Barley, Oats, Rye, Triticale, and Wheat): For additional control of certain seed- and/or soil-borne diseases and insect pests, Saltro may be combined with a seed treatment product containing difenoconazole, mefenoxam, sedaxane, and thiamethoxam. Corn (Field, Pop, Seed, and Sweet): For additional control of certain seed- and soil-borne diseases, Saltro may be combined with a seed treatment product containing azoxystrobin, fludioxonil, mefenoxam, sedaxane, and thiabendazole. For insect control, Saltro may be combined with a seed treatment product containing thiamethoxam. Cotton: For additional control of certain seed- and soil-borne diseases, Saltro may be combined with a seed treatment product containing azoxystrobin, fludioxonil, mefenoxam, and sedaxane. Legume Vegetables (Succulent or Dried) Crop Group 6: For additional control of certain seed- and/or soil-borne diseases and insect pests, Saltro may be combined with seed treatment products containing, fludioxonil, mefenoxam, picarbutrazox, sedaxane, thiabendazole, and thiamethoxam. Peanut: For additional control of certain seed- and soil-borne diseases, Saltro may be combined with a seed treatment product containing azoxystrobin, fludioxonil, and mefenoxam. Potato: For additional control of certain seed- and soil-borne pathogens, Saltro may be combined with Vibrance®, Vibrance Ultra Potato, Maxim® 4FS or Maxim PSP. For insect control, Saltro may be tank mixed with Cruiser® 5FS and for both disease and insect control, Saltro may be combined with CruiserMaxx® Potato Insecticide and Fungicide, CruiserMaxx Vibrance Potato. Registered dust-based fungicides with different active ingredients can be applied as a supplemental treatment after the Saltro treatment. If inert dust (fir bark, talc, etc.) or a dust-based fungicide is to be used, apply Saltro before applying the dust. Rapeseed (including canola) Crop Subgroup 20A: For additional control of certain seed- and/or soil-borne diseases, Saltro may be combined with seed treatment products containing difenoconazole, fludioxonil, mefenoxam, and sedaxane. On canola only, Saltro may be combined with a seed treatment product containing thiamethoxam for insect control and/or cyantraniliprole.

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Sorghum: For additional control of certain seed- and soil-borne diseases, Saltro may be combined with seed treatment products containing azoxystrobin, fludioxonil, mefenoxam, and sedaxane. Soybean: For additional control of certain seed-borne and soil-borne diseases and insect pests, Saltro may be combined with CruiserMaxx APX, or other seed treatment products containing azoxystrobin, fludioxonil, mefenoxam, picarbutrazox, sedaxane, thiabendazole, and or thiamethoxam.

5.0 RESTRICTIONS • Store treated seeds away from feed and foodstuffs. • Do not allow children, pets, or livestock to have access to treated seeds. • Wear long-sleeved shirt, long pants, and chemical-resistant gloves when handling treated seed. • Treated seeds exposed on soil surface may be hazardous to wildlife. Cover or collect treated seeds spilled during loading and planting. Do not allow treated seed to remain uncovered on the soil surface. • Dispose of all excess treated seed. Leftover treated seed may be double sown around the headland or buried away from water sources in accordance with local requirements. Do not contaminate water bodies when disposing of planting equipment washwater. • Treated seed must be planted into the soil at a depth of at least 1 inch. Ensure that all planted seeds are thoroughly incorporated by the planter during planting. Additional incorporation may be required to thoroughly cover exposed seeds. • Dispose of seed packaging in accordance with local requirements. • Excess treated seed may be used for ethanol production only if (1) by-products are not used for livestock feed, and (2) no measurable residues of pesticide remain in ethanol by-products that are used for agronomic practice. • Do not use in hopper-box, planter-box, slurry-box or other seed treatment applications at or immediately before planting.

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• In the event of a crop failure or harvest of a crop grown from seed treated with Saltro, the field may be replanted according to the following schedule: Crop, Crop Group, or Crop Subgroup Plant-Back Interval Brassica Head and Stem Vegetable, Crop Group 5-16 Bulb Vegetables, Crop Group 3-07 Cereals, Small Grain (barley, oats, rye, triticale, wheat) Corn (field, pop, seed, sweet) Cottonseed, Crop Subgroup 20C Cucurbit Vegetables, Crop Group 9 Fruiting Vegetables, Crop Group 8-10 Leaf Petiole Vegetables, Crop Subgroup 22B Leafy Greens, Crop Subgroup 4-16A Leaves of Root and Tuber Vegetables, Crop Group 2 Legume Vegetables, Succulent or Dried, Crop Group 6, Except Cowpea Forage and Cowpea Hay Mustard Greens and Brassica Leafy Greens, Crop Subgroup 4-16B Peanut Potato Quinoa Rapeseed (including canola), Crop Subgroup 20A Root Vegetables, Crop Subgroup 1A Soybean, Except Forage, Hay, and Silage Sorghum Strawberry Sunflower, Crop Subgroup 20B Tuberous and Corm Vegetables, Crop Subgroup 1C 0 days Grasses Grown for Seed Non-grass Animal Feeds, Crop Group 18 Rice Tobacco 30 days All other crops Intended for Food and Feed 365 days

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6.0 SEED CONTAINER LABEL REQUIREMENTS The Federal Seed Act requires that bags containing treated seeds shall be labeled with the following statements: • This seed has been treated with pydiflumetofen fungicide. • Do not use for feed, food, or oil purposes.

In addition, the U.S. Environmental Protection Agency requires the following statements on bags containing seed treated with Saltro fungicide: • Store away from feed and foodstuffs. • Do not allow children, pets, or livestock to have access to treated seeds. • Wear long-sleeved shirt, long pants, and chemical-resistant gloves when handling treated seed. • Treated seeds exposed on soil surface may be hazardous to wildlife. Cover or collect treated seeds spilled during loading and planting. Do not allow treated seed to remain uncovered on the soil surface. • Dispose of all excess treated seed. Leftover treated seed may be double sown around the headland or buried away from water sources in accordance with local requirements. Do not contaminate water bodies when disposing of planting equipment washwater. • Groundwater Advisory: Pydiflumetofen has properties and characteristics associated with chemicals detected in groundwater. This chemical may leach into groundwater if used in areas where soils are permeable, particularly where the water table is shallow. • Treated seed must be planted into the soil at a depth of at least 1 inch. Ensure that all planted seeds are thoroughly incorporated by the planter during planting. Additional incorporation may be required to thoroughly cover exposed seeds. • Do not feed or harvest soybean hay, forage, and silage. • Dispose of seed packaging in accordance with local requirements. • Excess treated seed may be used for ethanol production only if (1) by-products are not used for livestock feed, and (2) no measurable residues of pesticide remain in ethanol by-products that are used for agronomic practice. • For Cereals, Small Grain (Barley, Oats, Rye, Triticale, and Wheat): o DO NOT exceed 0.31 lb ai/A/year of pydiflumetofen-containing products through any combination of seed and foliar applications. o DO NOT exceed 0.168 lb ai/A/year of pydiflumetofen-containing products through any combination of seed and foliar applications to forage and hay. • For Corn (Field, Pop, Seed, and Sweet), DO NOT exceed 0.224 lb ai/A/year of pydiflumetofen-containing products through any combination of seed and foliar applications. • For Cottonseed Crop Subgroup 20C, DO NOT exceed 0.224 lb ai/A/year of pydiflumetofen-containing products through any combination of seed and foliar applications. • For Legume Vegetables (Succulent or Dried) Crop Group 6, DO NOT exceed 0.357 lb ai/A/year of pydiflumetofen-containing products through any combination of seed and foliar applications. • For Peanut, DO NOT exceed 0.18 lb ai/A/year of pydiflumetofen-containing products through any combination of seed and foliar applications.

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• For Potato, DO NOT exceed 0.33 lb ai/A/year of pydiflumetofen-containing products through any combination of seed and foliar applications. • For Rapeseed (including canola) Crop Subgroup 20A, DO NOT exceed 0.291 lb ai/A/year of pydiflumetofen-containing products through any combination of seed and foliar applications. • For Sorghum, DO NOT exceed 0.224 lb ai/A/year of pydiflumetofen-containing products through any combination of seed and foliar applications. • For Soybean, DO NOT exceed 0.357 lb ai/A/year of pydiflumetofen-containing products through any combination of seed and foliar applications. • This seed has been treated with X lb of pydiflumetofen per 100 lb seed. • In the event of crop failure or harvest of a crop grown from seed treated with Saltro, crops may be replanted according to the following schedule:

Crop, Crop Group, or Crop Subgroup Plant-Back Interval Brassica Head and Stem Vegetable, Crop Group 5-16 Bulb Vegetables, Crop Group 3-07 Cereals, Small Grain (barley, oats, rye, triticale, wheat) Corn (field, pop, seed, sweet) Cottonseed, Crop Subgroup 20C Cucurbit Vegetables, Crop Group 9 Fruiting Vegetables, Crop Group 8-10 Leaf Petiole Vegetables, Crop Subgroup 22B Leafy Greens, Crop Subgroup 4-16A Leaves of Root and Tuber Vegetables, Crop Group 2 Legume Vegetables, Succulent or Dried, Crop Group 6, Except Cowpea Forage and Cowpea Hay Mustard Greens and Brassica Leafy Greens, Crop Subgroup 4-16B Peanut Potato Quinoa Rapeseed (including canola), Crop Subgroup 20A Root Vegetables, Crop Subgroup 1A Soybean, Except Forage, Hay, and Silage Sorghum Strawberry Sunflower, Crop Subgroup 20B Tuberous and Corm Vegetables, Crop Subgroup 1C 0 days Grasses Grown for Seed Non-grass Animal Feeds, Crop Group 18 Rice Tobacco 30 days All other crops Intended for Food and Feed 365 days

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7.0 Seed Treatment Directions

7.1 Cereals, Small Grain Crops [– Not Registered for Use by California] Barley Oats Rye Triticale Wheat (Durum, Spring, Winter) Target Disease/Pest Use Rate fl oz product/100 lb seed mg ai/1,000 seeds* Seed rot and seedling blight caused by Fusarium spp. and Bipolaris sorokiniana (Cochliobolus sativus)

Early-season tan spot caused by Pyrenophora tritici- repentis

Early-season control of Powdery mildew caused by Blumaria graminis

0.08-0.62

Wheat: 0.76-6.11

Barley: 0.91-7.33

Oats: 0.70-5.59

Rye: 0.73-5.87

Triticale: 0.89-7.19 Suppression only:

Early-season Septoria tritici blotch caused by Zymoseptoria tritici

Fusarium root, crown and foot rot caused by Fusarium spp.

Common root rot caused by Cochliobolus sativus and Pink snow mold caused by Michrodochium nivale

Stagnospora nodorum blotch caused by seed-borne Parastagnospora nodorum

Seed-borne Fusarium head blight (scab) caused by Fusarium spp.

Plant Parasitic Nematodes: Cereal Cyst (Heterodera spp.) Lesion (Pratylenchus spp.) *Based on an average seed weight of: • 15,000 wheat grains/lb • 12,500 barley grains/lb • 16,400 oat grains/lb • 15,600 rye grains/lb • 12,750 triticale grains/lb Resistance Management: • Refer to Section 3.1. USE RESTRICTIONS • DO NOT exceed 0.31 lb ai/A/year of pydiflumetofen-containing products through any combination of seed and foliar applications. • DO NOT exceed 0.168 lb ai/A/year of pydiflumetofen-containing products through any combination of seed and foliar applications to forage and hay. • Sections 4.0, 4.1, 5.0, and 6.0 contain additional product use restrictions.

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7.2 Corn Crops Field Corn [– Not Registered for Use by California] Popcorn [– Not Registered for Use by California] Corn Grown for Seed (Field, Pop, or Sweet) [– Not Registered for Use by California] Sweet Corn [– Not Registered for Use by California] Target Disease/Pest Use Rate fl oz product mg ai/seed*

Seed-borne, soil-borne, and associated early- season seedling infections caused by Fusarium spp.

0.16-1.6 fl oz/100 lb field corn

0.070-0.70 fl oz/80,000 field corn kernels

0.35-3.5 fl oz/100 lb popcorn

0.28-2.8 fl oz/100 lb sweet corn

0.013-0.13

Plant Parasitic Nematodes: Dagger Nematode (Xiphinema spp.) Lance Nematode (Hoplolaimus spp.) Lesion Nematode (Pratylenchus spp.) Needle Nematode (Longidorus spp.) Pin Nematode (Paratylenchus spp.) Ring Nematode (Mesocriconema spp.) Root Knot Nematode (Meloidogyne spp.) Sheath nematode (Hemicycliophora spp.) Spiral Nematode (Helicotylenchus spp.) Sting Nematode (Belonolaimus spp.) Stubby Root Nematode (Paratrichodorus spp.) Stunt Nematode (Tylenchorhynchus spp.)

4.87-6.09 fl oz/100 lb field corn

2.18-2.71 fl oz/80,000 field corn kernels

10.83-13.53 fl oz/100 lb popcorn

8.66-10.83 fl oz/100 lb sweet corn

0.400-0.500 *Based on an average seed weight of: • 1,800 field corn kernels/lb • 4,000 popcorn kernels/lb • 3,200 sweet corn kernels/lb Resistance Management: • Refer to Section 3.1. USE RESTRICTIONS • DO NOT exceed 0.224 lb ai/A/year of pydiflumetofen-containing products through any combination of seed and foliar applications. • Sections 4.0, 4.1, 5.0, and 6.0 contain additional product use restrictions.

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7.3 Cottonseed – Crop Subgroup 20C Crops (Including cultivars, varieties, and/or hybrids of these) [ – Not Registered for Use by California] Cottonseed Target Disease/Pest Use Rate fl oz/100 lb seed mg ai/seed*

Seed-borne Fusarium spp.

Suppression only: Cotton Root-rot (Phymatotrichopsis omnivorum)

Plant Parasitic Nematodes: Lance (Hoplolaimus spp.) Lesion (Pratylenchus spp.) Root Knot (Meloidogyne incognita) Reniform (Rotylenchulus reniformis)

1.53-12.28 0.050-0.403 *Based on an average seed weight of 4,500 cottonseeds/lb Resistance Management: • Refer to Section 3.1. USE RESTRICTIONS • DO NOT exceed 0.224 lb ai/A/year of pydiflumetofen-containing products through any combination of seed and foliar applications. • Sections 4.0, 4.1, 5.0, and 6.0 contain additional product use restrictions.

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7.4 Legume Vegetables (Succulent or Dried) – Crop Group 6 Crops [– Not Registered for Use by California] Bean (Lupinus spp.) Grain Lupin, Sweet Lupin, White Lupin, White Sweet Lupin Bean (Phaseolus spp.) Field Bean, Kidney Bean, Lima Bean, Navy Bean, Pinto Bean, Runner Bean, Snap Bean, Tepary Bean, Wax Bean Bean (Vigna spp.) Adzuki Bean, Asparagus Bean, Blackeyed Pea, Catjang, Chinese Longbean, Cowpea, Crowder Pea, Moth Bean, Mung Bean, Rice Bean, Southern Pea, Urd Bean, Yardlong Bean Pea (Pisum spp.) Dwarf Pea, Edible-pod Pea, English Pea, Field Pea, Garden Pea, Green Pea, Snow Pea, Sugar Snap Pea Broad Bean (fava bean) (Vicia faba) Chickpea (garbanzo bean) (Cicer arietinum) Guar (Cyamopsis tetragonoloba) Jackbean (Canavalia ensiformis) Lablab Bean (hyacinth bean) (Lablab purpureus) Lentil (Lens esculenta) Pigeon Pea (Cajanus cajan) Soybean, (immature seed) (edamame) (Glycine max) Sword Bean (Canavalia gladiata) Target Disease/Pest Use Rate fl oz/100 lb seed mg ai/1,000 seeds* Ascochyta Blight caused by seed-borne Ascochyta spp.

Black root rot caused by Fusarium solani

Botrytis gray mold caused by seed-borne Botrytis cinerea

Fusarium root rot caused by Fusarium spp.

White mold caused by seed-borne Scerotinia sclerotiorum

0.15-1.53 Beans1: 18-181

Peas2: 12-118

Chickpea3: 25-252

Cowpea4: 7-71

Lentil5: 2-21

Suppression only:

Plant Parasitic Nematodes: Lesion (Pratylenchus spp.) Root Knot (Meloidogyne spp.)

*Based on an average seed weight of:

1. 1,250 beans/lb
2. 1,930 peas/lb
3. 900 chickpeas/lb
4. 3,200 cowpeas/lb
5. 10,600 lentils/lb Resistance Management: • Refer to Section 3.1. USE RESTRICTIONS • DO NOT feed or harvest cowpea forage and hay. • DO NOT exceed 0.357 lb ai/A/year of pydiflumetofen-containing products through any combination of seed and foliar applications. • Sections 4.0, 4.1, 5.0, and 6.0 contain additional product use restrictions.

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7.5 Peanut Crops [– Not Registered for Use by California] Peanut Target Disease/Pest Use Rate fl oz/100 lb seed mg ai/seed*

Seed-borne Fusarium spp.

Suppression only: Aspergillus Crown Rot (Aspergillus niger)

0.31-0.61 0.050-0.106 *Based on an average seed weight of 850 peanuts/lb Resistance Management: • Refer to Section 3.1. USE RESTRICTIONS • DO NOT exceed 0.18 lb ai/A/year of pydiflumetofen-containing products through any combination of seed and foliar applications. • Sections 4.0, 4.1, 5.0, and 6.0 contain additional product use restrictions.

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7.6 Potato Crops [– Not Registered for Use by California] Potato Target Disease/Pest Use Rate fl oz/100 lb of seed mg ai/seed

Fusarium dry rot (Fusarium spp.) Seed-borne silver scurf (Helminthosporium solani)

Suppression only:-

Plant Parasitic Nematodes: Root Knot Nematode (Meloidogyne spp.) Lesion Nematode (Pratylenchus spp.) Stubby Root Nematode (Paratrichodorus spp.) Sting Nematode (Belonolaimus spp.)

0.039 – 0.062 0.71 – 1.13 USE INFORMATION • The mg ai/seed rate provided is based on an average seed weight of 8 potato seed tubers per pound. • Saltro requires dilution prior to atomization and application to potato seed tubers. • A volume of 2 - 4 fl oz of slurry mixture/100 lb of potato seed tubers is recommended. • For best results, calibrate the equipment so that every potato seed tuber is uniformly coated with a fine layer of the slurry mix, without any excess dripping out of the treated seed. Applying excess moisture may predispose the seed to rotting, resulting in poor emergence and stand. • Apply Saltro only in well-ventilated areas. • In high humidity, use drying fans on the treated potato seed pieces. If possible, allow treated tubers to dry during transit and plant the same day as treatment after potatoes have been cut. • Treated Seed Storage: If potato seed pieces must be stored before planting, consult your local Syngenta representative for information on best management practices for handling and storing treated seed potatoes, including the use of an EPA-approved dye or colorant that imparts an unnatural color (green or red is recommended) to the seed as stated in 40 CFR 153.155 (c). • If the treated potato seed tubers need to be stored or held for a few days, then make sure that the treated seed tubers are stored in well-ventilated areas that allow air to move through and out of the treated potato seed tubers. An ideal air temperature for storage is 60°F at a relative humidity of 85 - 90%. Avoid free moisture forming within or around the treated potato seed tubers during storage. Resistance Management: • Refer to Section 3.1. USE RESTRICTIONS • DO NOT exceed 0.33 lb ai/A/year of pydiflumetofen-containing products through any combination of seed and foliar applications. • Sections 4.0, 4.1, 5.0, and 6.0 contain additional product use restrictions. • DO NOT BAG POTATO SEED TUBERS THAT HAVE BEEN TREATED WITH A LIQUID SEED TREATMENT.

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7.7 Rapeseed (including Canola) – Crop Subgroup 20A

Crops (Including cultivars, varieties, and/or hybrids of these) [ – Not Registered for Use by California] Borage Canola Crambe Cuphea Echium Flax seed Gold of pleasure Hare’s ear mustard Lesquerella Lunaria Meadowfoam Milkweed Mustard seed Oil radish Poppy seed Rapeseed Sesame Sweet rocket Target Disease/Pest Use Rate fl oz/100 lb seed grams ai/100 kg seed Control of seed- and airborne blackleg caused by Leptosphaeria maculans 1.23 (80 ml/100 kg seed) 40 Resistance Management: • Refer to Section 3.1. USE RESTRICTIONS • DO NOT exceed 0.291 lb ai/A/year of pydiflumetofen-containing products through any combination of seed and foliar applications. • Sections 4.0, 4.1, 5.0, and 6.0 contain additional product use restrictions.

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7.8 Sorghum Crops [– Not Registered for Use by California] Sorghum Target Disease/Pest Use Rate fl oz product /100 lb seed mg ai/seed*

Seed-borne Fusarium spp.

Suppression Only: Plant Parasitic Nematodes: Dagger Nematode (Xiphinema spp.) Lance Nematode (Hoplolaimus spp.) Lesion Nematode (Pratylenchus spp.) Needle Nematode (Longidorus spp.) Pin Nematode (Paratylenchus spp.) Ring Nematode (Mesocriconema spp.) Root Knot Nematode (Meloidogyne spp.) Sheath nematode (Hemicycliophora spp.) Spiral Nematode (Helicotylenchus spp.) Sting Nematode (Belonolaimus spp.) Stubby Root Nematode (Paratrichodorus spp.) Stunt Nematode (Tylenchorhynchus spp.)

0.10-0.88 0.001-0.009 *Based on an average seed weight of 14,500 sorghum grains/lb Resistance Management: • Refer to Section 3.1. USE RESTRICTIONS • DO NOT exceed 0.224 lb ai/A/year of pydiflumetofen-containing products through any combination of seed and foliar applications. • Sections 4.0, 4.1, 5.0, and 6.0 contain additional product use restrictions.

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7.9 Soybean Crops [– Not Registered for Use by California] Soybean Target Disease/Pest Use Rate fl oz product mg ai/seed*

Sudden Death Syndrome (Fusarium virguliforme)

Early-season Septoria Brown Spot (Septoria glycines)

Soybean Charcoal Rot (Macrophomina phaseolina)

Plant Parasitic Nematodes: Soybean Cyst (Heterodera glycines) Root Knot (Meloidogyne incognita) Reniform (Rotylenchulus reniformis) Lesion (Pratylenchus spp.) Lance (Hoplolaimus spp.)

1.52 – 3.04 fl oz/ 100 lbs soybean

0.714 – 1.428 fl oz/ 140,000 soybean seeds

0.075 – 0.150 *Based on an average seed weight of 3,000 soybeans/lb Resistance Management: • Refer to Section 3.1. USE RESTRICTIONS • DO NOT feed or harvest soybean hay, forage, and silage. • DO NOT exceed 0.357 lb ai/A/year of pydiflumetofen-containing products through any combination of seed and foliar applications. • Sections 4.0, 4.1, 5.0, and 6.0 contain additional product use restrictions.

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8.0 STORAGE AND DISPOSAL

STORAGE AND DISPOSAL Do not contaminate water, food or feed by storage or disposal.

Pesticide Storage Keep this product in its tightly closed original container, when not in use. Store in a cool, dry (preferably locked) area that is inaccessible to children and animals.

Pesticide Disposal Pesticide wastes may be hazardous. Improper disposal of excess pesticide, spray mixture, or rinsate is a violation of federal law. If these wastes cannot be disposed of by use according to label instructions, contact your State Pesticide or Environmental Control Agency, or the Hazardous Waste representative of the nearest EPA Regional Office for guidance.

Container Handling [(less than or equal to 5 gallons)] Non-refillable container. Do not reuse or refill this container. Triple rinse container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank and drain for 10 seconds after the flow begins to drip. Add water – at least 2% of the container volume, and up to 1/3 of the volume of water needed to make the proper slurry composition with a maximum of 1/4 of the container volume – and recap. Shake for 30 seconds. Pour rinsate into application equipment or a mix tank or store rinsate for later use or disposal. Drain for 10 seconds after the flow begins to drip. Repeat this procedure two more times. If used in application equipment, adjust the slurry volume application rate to account for any added rinsate water. Then offer for recycling if available or puncture and dispose of in a sanitary landfill or by other procedures approved by state and local authorities.

Container Handling [(greater than 5 gallons)] Non-refillable container. Do not reuse or refill this container. Triple rinse container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank. Add water – at least 2% of the container volume, and up to 1/3 of the volume of water needed to make the proper slurry composition with a maximum of 1/4 of the container volume. Replace and tighten closures. Tip container on its side and roll it back and forth, ensuring at least one complete revolution, for 60 seconds. Stand the container on its end and tip it back and forth several times. Turn the container over onto its other end and tip it back and forth several times. Empty the rinsate into application equipment or a mix tank or store rinsate for later use or disposal. Repeat this procedure two more times. If used in application equipment, adjust the slurry volume application rate to account for any added rinsate water. Then offer for recycling if available or puncture and dispose of in a sanitary landfill or by other procedures approved by state and local authorities.

Container Handling [(greater than 5 gallons)] Refillable container. Refill this container with pesticide only. Do not reuse the container for any other purpose. Cleaning the container before final disposal is the responsibility of the person disposing of the container. Cleaning before refilling is the responsibility of

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the refiller. To clean container before final disposal, empty the remaining contents from this container into application equipment or mix tank. Add water – at least 2% of the container volume, and up to 1/3 of the volume of water needed to make the proper slurry composition with a maximum of 1/4 of the container volume. Replace and tighten closure. Agitate vigorously or recirculate the rinsate with a pump for at least 2 minutes, ensuring that the rinsate rinses the walls of the container. Empty the rinsate into application equipment or rinsate collection system, for later use or disposal. Repeat this procedure two more times. If used in application equipment, adjust the slurry volume application rate to account for any added rinsate water. Then offer for recycling if available or puncture and dispose of in a sanitary landfill, or by incineration, or by other procedures approved by state and local authorities.

CONTAINER IS NOT SAFE FOR FOOD, FEED OR DRINKING WATER.

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9.0 CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY

NOTICE: Read the entire Directions for Use and Conditions of Sale and Limitation of Warranty and Liability before buying or using this product. If the terms are not acceptable, return the product at once, unopened, and the purchase price will be refunded. The Directions for Use of this product must be followed carefully. It is impossible to eliminate all risks inherently associated with the use of this product. Crop injury, ineffectiveness or other unintended consequences may result because of such factors as manner of use or application, weather or crop conditions, presence of other materials or other influencing factors in the use of the product, which are beyond the control of SYNGENTA CROP PROTECTION, LLC or Seller. To the extent permitted by applicable law, Buyer and User agree to hold SYNGENTA and Seller harmless for any claims relating to such factors.

SYNGENTA warrants that this product conforms to the chemical description on the label and is reasonably fit for the purposes stated in the Directions for Use, subject to the inherent risks referred to above, when used in accordance with directions under normal use conditions. To the extent permitted by applicable law: (1) this warranty does not extend to the use of the product contrary to label instructions, or under conditions not reasonably foreseeable to or beyond the control of Seller or SYNGENTA, and (2) Buyer and User assume the risk of any such use. TO THE EXTENT PERMITTED BY APPLICABLE LAW, SYNGENTA MAKES NO WARRANTIES OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE NOR ANY OTHER EXPRESS OR IMPLIED WARRANTY EXCEPT AS WARRANTED BY THIS LABEL.

To the extent permitted by applicable law, in no event shall SYNGENTA be liable for any incidental, consequential or special damages resulting from the use or handling of this product. TO THE EXTENT PERMITTED BY APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE USER OR BUYER, AND THE EXCLUSIVE LIABILITY OF SYNGENTA AND SELLER FOR ANY AND ALL CLAIMS, LOSSES, INJURIES OR DAMAGES (INCLUDING CLAIMS BASED ON BREACH OF WARRANTY, CONTRACT, NEGLIGENCE, TORT, STRICT LIABILITY OR OTHERWISE) RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, SHALL BE THE RETURN OF THE PURCHASE PRICE OF THE PRODUCT OR, AT THE ELECTION OF SYNGENTA OR SELLER, THE REPLACEMENT OF THE PRODUCT.

SYNGENTA and Seller offer this product, and Buyer and User accept it, subject to the foregoing Conditions of Sale and Limitation of Warranty and Liability, which may not be modified except by written agreement signed by a duly authorized representative of SYNGENTA.

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ADEPIDYN®, Cruiser®, CruiserMaxx®, Maxim®, Saltro®, Trebuset®, Vibrance®, the ALLIANCE FRAME the SYNGENTA Logo, and the PURPOSE ICON are Trademarks of a Syngenta Group Company

Viton™ is a trademark of The Chemours Company FC, LLC © 20XX Syngenta

For non-emergency (e.g., current product information), call Syngenta Crop Protection at 1-866-796-4368.

Manufactured for: Syngenta Crop Protection, LLC P.O. Box 18300 Greensboro, North Carolina 27419-8300

Saltro 1648 MAS 0223 AMEND-D 1123-CL – jeb – 06/16/2025 000100-01648.20231110D.SALTRO_AMEND_NOV2023-CL.PDF