crop-chem-docs/corpus/epa_ppls/264-1126.md

Gem RC Fungicide

• EPA Reg No: 264-1126
• Registrant: BAYER CROPSCIENCE, LLC
• Signal word: Caution
• Active ingredients: Trifloxystrobin (42.6%)
• Label accepted: 2023-08-02
• Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000264-01126-20230802.pdf

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UNITED STATES ENVIRONMENTAL PROTECTION AGENCY WASHINGTON, DC 20460

OFFICE OF CHEMICAL SAFETY AND POLLUTION PREVENTION

August 2, 2023

Megan Mader Regulatory Affairs Manager, Fruits and Vegetables Bayer CropScience LP 800 N. Lindbergh Blvd. St. Louis, MO 63167

Subject: Registration Review La bel Mitigation for TRIFLOXYSTROBIN Product Name: GEM RC FUNGICIDE EPA Registration Number: 264-1126 Application Date: June 7, 2022 Decision Number: 553114

Dear Megan Mader:

The Agency, in accordance with the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA), as amended, has completed reviewing all the information submitted with your application to support the Registration Review of the above referenced product in connection with the Trifloxystrobin Interim Decision, and has concluded that your submission is acceptable. The label referred to above, submitted in connection with registration under FIFRA, as amended, is acceptable.

Should you wish to add/retain a reference to the company’s website on your label, then please be aware that the website becomes labeling under the Federal Insecticide Fungicide and Rodenticide Act and is subject to review by the Agency. If the website is false or misleading, the product would be misbranded and unlawful to sell or distribute under FIFRA section 12(a)(1)(E). 40 CFR 156.10(a)(5) list examples of statements EPA may consider false or misleading. In addition, regardless of whether a website is referenced on your product’s label, claims made on the website may not substantially differ from those claims approved through the registration process. Therefore, should the Agency find or if it is brought to our attention that a website contains false or misleading statements or claims substantially differing from the EPA approved registration, the website will be referred to the EPA’s Office of Enforcement and Compliance.

A stamped copy of your labeling is enclosed for your records. This labeling supersedes all previously accepted labeling. You must submit one copy of the final printed labeling before you release the product for shipment with the new labeling. In accordance with 40 CFR 152.130(c), you may distribute or sell this product under the previously approved labeling for 12 months from the date of this letter. After 12 months, you may only distribute or sell this product if it bears this new revised labeling or subsequently approved labeling. “To distribute or sell” is defined under FIFRA section 2(gg) and its implementing regulation at 40 CFR 152.3.

Page 2 of 2 EPA Reg. No. 264-1126 Decision No. 553114

If you have any questions about this letter, please contact DeMariah Koger by phone at (202)- 566-2288, or via email at koger.demariah@epa.gov.

S i n c e r e l y ,

       Linda Arrington, Branch Chief Risk Management and Implementation Branch 4 Pesticide Re-Evaluation Division Office of Pesticide Programs

Enclosure

1 TRIFLOXYSTROBIN GROUP 11 FUNGICIDE Gem® RC Fungicide For control of certain diseases in potatoes, rice, soybean, and sugar beets. Active Ingredient: Trifloxystrobin, (E,E)-alpha-(methoxyimino)-2-[[[[1-[3-(trifluoromethyl)phenyl] ethylidene]amino]oxy]methyl]-,methylester ............42.6% Other Ingredients: ............................................................................................................................... .......................................... 57.4% Contains 4.17 pounds trifloxystrobin per gallon. 100.0% EPA Reg. No. 264-1126 EPA Est. No. 264-MO-02 STOP - Read the label before use KEEP OUT OF REACH OF CHILDREN CAUTION AVISO Si usted no entiende la etiqueta, busque a alguien para que se la explique a used en detalle. (If you do not understand the label, find someone to explain it to you in detail). For MEDICAL And TRANSPORTATION Emergencies ONLY Call 24 Hours A Day 1-800-334-7577 For PRODUCT USE Information Call 1-866-99BAYER (1-866-992-2937) FIRST AID IF INHALED: x Move person to fresh air. x If person is not breathing, call 911 or an ambulance, then give artificial respiration, preferably mouth-to-mouth if possible. x Call a poison control center or doctor for further treatment advice. IF SWALLOWED: x Immediately call a poison control center or doctor for treatment advice. x Do not induce vomiting unless told to do so by a poison control center or doctor. x Have person sip a glass of water if able to swallow. x Do not give anything by mouth to an unconscious person. IF ON SKIN: x Take off contaminated clothing. x Rinse skin immediately with plenty of water for 15-20 minutes. x Call a poison control center or doctor for treatment advice. IF IN EYES: x Hold eye open and rinse slowly and gently with water for 15-20 minutes. x Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye. x Call a poison control center or doctor for treatment advice. For MEDICAL Emergencies Call 24 Hours A Day 1-800-334-7577. Have the product container or label with you when calling a poison control center or doctor or going for treatment. NOTE TO PHYSICIAN: Treat Symptomatically. Aug 02, 2023 264-1126

2 PRECAUTIONARY STATEMENTS HAZARDS TO HUMANS AND DOMESTIC ANIMALS CAUTION Harmful if swallowed, inhaled, or absorbed through skin. Avoid breathing vapor or spray mist and contact with skin, eyes, or clothing. Wash thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco, or using the toilet. Remove and wash contaminated clothing before reuse. Personal Protective Equipment (PPE): Applicators and other handlers must wear: x Long-sleeved shirt and long pants x Waterproof gloves x Shoes plus socks Follow manufacturer’s instructions for cleaning/maintaining PPE. If no such instructions exist for washables, use detergent and hot water. Keep and wash PPE separately from other laundry. Engineering Control Statements When handlers use closed systems, enclosed cabs, or aircraft in a manner that meets the requirements listed in the Worker Protection Standard (WPS) for agricultural pesticides [40 CFR 170.607 (d)(e)(f)], the handler PPE requirements may be reduced or modified as specified in the WPS. User Safety Recommendations Users should: • Wash hands before eating, drinking, chewing gum, using tobacco, or using the toilet. • Remove clothing immediately if pesticide gets inside. Then wash thoroughly and put on clean clothing. • Wash the outside of gloves before removing. As soon as possible, wash thoroughly and change into clean clothing. ENVIRONMENTAL HAZARDS This pesticide is toxic to fish and aquatic invertebrates. Applying this product when rain is not predicted for the next 24 hours will help reduce potential risk to aquatic invertebrates by reducing pesticide runoff from the treatment area into water bodies. Do not apply directly to water, or to areas where surface water is present, or to intertidal areas below the mean high water mark. Drift and runoff may be hazardous to aquatic organisms in water adjacent to treated areas. Do not contaminate water when disposing of equipment wash water or rinsate. Ground Water Advisory Several trifloxystrobin degradates have properties and characteristics associated with chemicals detected in ground water. The use of this chemical in areas where soils are permeable, particularly where the water table is shallow, may result in ground water contamination. PHYSICAL OR CHEMICAL HAZARDS Do not use, pour, spill, or store near heat or open flame.

3 DIRECTIONS FOR USE It is a violation of federal law to use this product in a manner inconsistent with its labeling. Do not apply this product in a way that will contact workers or other persons, either directly or through drift. Only protected handlers may be in the area during application. For any requirements specific to your State or Tribe, consult the agency responsible for pesticide regulation. Rice paddy water must be held for a minimum of 7 days after application. AGRICULTURAL USE REQUIREMENTS Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR part 170. This Standard contains requirements for the protection of agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of agricultural pesticides. It contains requirements for training, decontamination, notification, and emergency assistance. It also contains specific instructions and exceptions pertaining to the statements on this label about personal protective equipment (PPE) and restricted- entry interval. The requirements in this box only apply to uses of this product that are covered by the Worker Protection Standard. Do not enter or allow worker entry into treated areas during the restricted-entry interval (REI) of 12 hours. PPE required for early entry to treated areas that is permitted under the Worker Protection Standard and that involves contact with anything that has been treated, such as plants, soil, or water is: • Coveralls • Waterproof gloves • Shoes plus socks STORAGE AND DISPOSAL Do not contaminate water, food, or feed by storage or disposal. Pesticide Storage: Store in a cool, dry place and in such a manner as to prevent cross-contamination with other pesticides, fertilizers, food, and feed. Store in original container and out of the reach of children, preferably in a locked storage area. Handle and open container in a manner as to prevent spillage. If the container is leaking or material spilled for any reason or cause, carefully sweep material into a pile. Refer to Precautionary Statements on label for hazards associated with the handling of this material. Do not walk through spilled material. Dispose of pesticide as directed below. In spill or leak incidents, keep unauthorized people away. You may contact the Bayer CropScience Emergency Response Team for decontamination procedures or any other assistance that may be necessary. The Bayer CropScience Emergency Response Telephone No. is 1-800-334-7577. Pesticide Disposal: Pesticide wastes may be toxic. Improper disposal of unused pesticide, spray mixture, or rinse water is a violation of federal law. If these wastes cannot be used according to label instruction, contact your State Pesticide or Environmental Control Agency, or the Hazardous Waste representative at the nearest EPA Regional Office for guidance in proper disposal methods. Container Disposal: Non-refillable container. Do not reuse or refill this container. Triple rinse or pressure rinse container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank and drain for 10 seconds after the flow begins to drip. Fill the container ¼ full with water and recap. Shake for 10 seconds. Pour rinsate into application equipment or a mix tank or store rinsate for later use or disposal. Drain for 10 seconds after the flow begins to drip. Repeat this procedure two more times. Pressure rinse as follows: Empty the remaining contents into application equipment or a mix tank and continue to drain for 10 seconds after the flow begins to drip. Hold container upside down over application equipment or mix tank or collect rinsate for later use or disposal. Insert pressure rinsing nozzle in the side of the container, and rinse at about 40 PSI for at least 30 seconds. Drain for 10 seconds after the flow begins to drip. Offer for recycling, if available. If not recycled, then puncture and dispose of in a sanitary landfill or by incineration, or, if allowed by State and local authorities, by burning. If burned, stay out of smoke. GENERAL INFORMATION Gem® RC Fungicide is a broad spectrum fungicide for the control of certain diseases in potatoes, rice, soybean, and sugar beets. Gem® RC Fungicide works by interfering with respiration in plant pathogenic fungi. Gem® RC Fungicide is a potent inhibitor of spore germination and mycelial growth. UNDER CERTAIN CONDITIONS CONDUCIVE TO EXTENDED INFE CTION PERIODS, ADDITIONAL FUNGICIDE APPLICATIONS BEYOND THE NUMBER ALLOWED BY THIS LABEL MAY BE NEEDED. UNDER THESE CONDITIONS, USE ANOTHER FUNGICIDE REGISTERED FOR THE CROP/DISEASE.

4 FUNGICIDE RESISTANCE MANAGEMENT For resistance management, Gem® RC Fungicide contains a Group 11 fungicide. Any fungal population may contain individuals naturally resistant to Gem® RC Fungicide and other Group 11 fungicides. A gradual or total loss of pest control may occur over time if these fungicides are used repeatedly in the same fields. Appropriate resistance-management strategies should be followed. To delay fungicide resistance, take one or more of the following steps: x Rotate the use of Gem® RC Fungicide or other Group 11 fungicides within a growing season sequence with different groups that control the same pathogens. x Use tank mixtures with fungicide from a different group that are equally effective on the target pest when such use is permitted. Use at least the minimum application rate as labeled by the manufacturer. x Adopt an integrated disease management program for fungicide use that includes scouting, uses historical information related to pesticide use, and crop rotation, and which considers host plant resistance, impact of environmental conditions on disease development, disease thresholds, as well as cultural, biological and other chemical control practices. x Where possible, make use of predictive disease models to effectively time fungicide applications. Note that using predictive models alone is not sufficient to manage resistance. x Contact your local extension specialist or certified crop advisor for any additional pesticide resistance-management and/or IPM recommendations for specific crops and pathogens. x For further information or to report suspected resistance contact Bayer CropScience at 1-866-99BAYER (1-866-992-2937). You can also contact your pesticide distributor or university extension specialist to report resistance. IPM: Applications of fungicides should be integrated into an overall disease and pest management program. Cultural practices known to reduce disease development should be followed. Consult your local extension specialist, certified crop advisor and/or manufacturer representative for additional IPM strategies established for your area. Gem® RC Fungicide may be used in Agricultural Extension advisory (disease forecasting or risk assessment) programs that prescribe application timings based on environmental factors favorable for disease development. Product performance: Monitor efficacy of all fungicides used in the disease management program against the targeted pathogen by recording factors that may influence fungicide performance and/or disease development. If a fungicide appears to be less effective against a pathogen that it previously controlled or suppressed, contact a manufacturer representative, local extension specialist, or certified crop advisor for further investigation. SPRAY EQUIPMENT Thorough coverage is necessary to provide good disease control. Applications using sufficient water volume to provide thorough and uniform coverage generally provide the most effective disease control. For ground application equipment, a minimum of 10 gal./A is prescribed. For aerial application equipment, a minimum of 2 gal./A is prescribed for soybeans, and 5 gal./A for other crops. Not registered for aerial application in New York State. Broadcast Ground Sprayers Equip sprayers with nozzles that provide accurate and uniform application. Be certain that nozzles are the same size and uniformly spaced across the boom. Calibrate the sprayer before use, and replace worn or damaged nozzles. Use a pump with the capacity to: (1) maintain a minimum of 35 psi at nozzles, and (2) provide sufficient agitation in the tank to keep the mixture in suspension – this requires recirculation of 10% of the tank volume per minute. Use jet agitators or a liquid sparge tube for vigorous agitation. Use screens to protect the pump and to prevent nozzles from clogging. Screens placed on the suction side of the pump should be 16- mesh or coarser. Do not place a screen in the recirculation line. Use 50-mesh screens at the nozzles. Check nozzle manufacturer’s recommendations. For information on spray equipment and calibration, consult sprayer manufacturer’s and/or state recommendations. For specific local directions and spray schedules, consult the current state agricultural experiment station recommendations. Aerial Application Avoid application under conditions when uniform coverage cannot be obtained or when excessive spray drift may occur. Do not apply directly to humans or animals. Chemigation: Apply Gem® RC Fungicide through irrigation equipment only to crops and diseases for which the chemigation use is specified. Under preventative or light disease pressures the low rate may be applied. Under moderate disease pressures, apply the highest rate allowed and use the shorter spray intervals. DIRECTIONS FOR USE THROUGH SPRINKLER IRRIGATION SYSTEMS Apply this product only through sprinkler irrigation systems including Hand move, solid set, wheel lines, linear, and center piv ot. Do not apply this product through any other type of irrigation system. Illegal pesticide residues in the crop can result from non-unif orm distribution of treated water. For specific information about calibration, contact State Extensio n Service Specialists, equipment manufacturers or other irrig ation experts. SPRAY PREPARATION: Remove scale, pesticide residues, and other foreign matter from the chemical tank and entire injector system. Flush with clean water.

5 APPLICATION INSTRUCTIONS: First prepare a suspension of Gem ® RC Fungicide in a mix tank. Fill tank with 1/2 to 3/4 the desired amount of water. Start mechanical or hydraulic agitation. Add the required amount of Gem ® RC Fungicide and then the remaining volume of water. Start sprinkler and uniformly inject the suspension of Gem® RC Fungicide into the irrigation water line so as to deliver the desired rate per acre. The suspension of Gem ® RC Fungicide should be injected with a positive displacement pump into the main line ahead of a right angle turn to insure adequate mixing. If you should have any other questions about calibration, you shou ld contact State Extension Service specialists, equipment manufacturers or other experts. NOTE: When treatment with Gem ® RC Fungicide has been completed, further field irrigation over the treated area should be avoided for 24 hours to prevent washing the chemical off the crop. GENERAL PRECAUTIONS FOR APPLICATIONS THROUGH SPRINKLER IRRIGATION SYSTEMS Maintain continuous agitation in mix tank during mixing and application to assure a uniform suspension. Greater accuracy in calibration and distribution will be achieved by injecting a larger volume of a more dilute solution per unit time. The system must contain a functional check valve, vacuum relief valve, and low pressure drain appropriately located on the irrigation pipeline to prevent water source contamination from backflow. The pesticide injection pipeline must contain a functional, automatic, quick-closing check valve to prevent the flow of fluid back toward the injection pump. The pesticide injection pipeline must also contain a functional, normally closed solenoid-operated valve located on the intake side of the injection pump and connected to the system interlock to prevent fluid from being withdrawn from the supply tank when the irrigation system is either automatically or manually shutdown. The system must contain functional interlocking controls to automatically shut off the pesticide injection pump when the water pump motor stops. The irrigation line or water pump must include a functional pressure switch which will stop the water pump motor when the water pressure decreases to the point where pesticide distribution is adversely affected. Systems must use a metering pump, such as a positive displacement injection pump (e.g., diaphragm pump) effectively designed and constructed of materials that are compatible with pesticides and capable of being fitted with a system interlock. Do not apply when wind speed favors drift beyond the area intended for treatment. If you are unsure of wind conditions which result in drift, contact your local extension agent. Do not apply when wind speed favors drift, when system connection or fittings leak, when nozzles do not provide uniform distribution or when lines containing the product must be dismantled and drained. Crop injury, lack of effectiveness, or illegal pesticide residues in the crop may result from non-uniform distribution of treated water. Allow sufficient time for pesticide to be flushed through all lines and all nozzles before turning off irrigation water. A person knowledgeable of the chemigation system and responsible for its operation shall shut the system down and make necessary adjustments should the need arise. Do not connect an irrigation system (including greenhouse systems) used for pesticide application to a public water system unless the label-prescribed safety devices for public water supplies are in place. MIXING PROCEDURES Prepare no more spray mixture than is needed for the immediate o peration. Thoroughly clean spray equipment before using this product. Vigorous agitation is necessary for proper dispersal of the product. Maintain maximum agitation throughout the spraying operation. Do not let the spray mixture stand overnight in the spray tank. Flush the spray equipment thoroughly foll owing each use and apply the rinsate to a previously treated area. Gem® RC Fungicide Alone: Add approximately 1/2 of the required amount of water to the mix tank. With the agitator running, add the Gem® RC Fungicide to the tank. Continue agitation while adding the rema inder of the water. Begin application of the solution after the Gem® RC Fungicide has completely and uniformly dispersed into the mix water. Maintain agitation until all of the mixture has been applied. Gem® RC Fungicide + Tank Mix Partners: Add approximately 1/2 of the required amount of water to the mix tank. Start the agitator running before adding any tank-mix partners. In general, tank-mix partners should be added in this order: products packaged in water- soluble packaging*, wettable powders, wettable granules (dry flowables), liquid flowables such as Gem ® RC Fungicide, liquids, and emulsifiable concentrates. Always allow each tank-mix partner to become fully and uniformly dispersed before adding the next p roduct. Provide sufficient agitation while adding the remainder of the water. Maintain agitation until all of the mixture has been applied. *N o t e : When using Gem® RC Fungicide in tank mixtures, all products in water-soluble packaging should be added to the tank before any other tank mix partner, including Gem ® RC Fungicide. Allow the water-soluble packaging to completely dissolve and the product(s) to completely disperse before adding any other tank-mix partner to the tank. If using Gem ® RC Fungicide in a tank mixture, observe all directions for us e, crop/sites, use rates, dilution ratios, precautions, and limitations which appear on the tank-mix product label. Do not exceed the label ’s dosage rate, and the most restrictive label precautions and limitations must be followed. This product must not be mixed with any product which prohibits such mixing. Tan k mixtures or other applications of products referenced on this label are permitted only in those states in which the referenced p roducts are registered. Gem® RC Fungicide is compatible with most insecticide, fungicide, and foliar nutrient products. However, the physical compatibility of Gem® RC Fungicide with tank-mix partners should be tested before use. To determine the physical compatibility of Gem ® RC Fungicide with other products, use a jar test, as described below. Using a quart jar, add the proportionate amounts of the products to 1 qt. of water. Add wettable powders and water-dispersible granular products first, then liquid flowables, and emulsifiable concentrat es last. After thoroughly mixing, let stand for at least 5 m inutes. If the combination remains mixed or can be remixed readily, it is physically compatible. Once compatibility has been proven, use the same procedure for adding required ingredients to the spray tank.

6 The crop safety of all potential tank mixes including additives and other pestic ides on all crops has not been tested. Before applying any tank mixture not specifically listed on this label, the safety to the target crop must be confirmed. To test for crop safety, apply Gem ® RC Fungicide to the target crop in a small area and in accordance with label instructions for the target crop. SPRAY DRIFT MANAGEMENT Aerial Applications x For aerial applications, do not apply when wind speeds exceed 15 mph at the application site. If the wind speed is greater than 10 mph, the boom length must be 65% or less of the wingspan for fixed wing aircraft and 75% or less of the rotor diameter for helicopters. Otherwise, the boom length must be 75% or less of the wingspan for fixed-wing aircraft and 90% or less of the rotor diameter for helicopters. x Do not release spray at a height greater than 10 ft above the ground or vegetative canopy, unless a greater application height is necessary for pilot safety. x Applicators must use ½ swath displacement upwind at the downwind edge of the field. x Do not apply during temperature inversions. Airblast applications x Sprays must be directed into the canopy. x Do not apply when wind speeds exceed 15 miles per hour at the application site. x User must tum off outward pointing nozzles at row ends and when spraying outer row. x Do not apply during temperature inversions Ground Boom Applications x Apply with the nozzle height recommended by the manufacturer, but no more than 4 feet above the ground or crop canopy. x Applicators are required to use a medium or coarser droplet size (ASABE S572). x Do not apply when wind speeds exceed 15 miles per hour at the application site. x Do not apply during temperature inversions. SPRAY DRIFT ADVISORIES THE APPLICATOR IS RESPONSIBLE FOR AVOIDING OFF-SITE SPRAY DRIFT BE AWARE OF NEARBY NON-TARGET SITES AND ENVIRONMENTAL CONDITIONS. IMPORTANCE OF DROPLET SIZE An effective way to reduce spray drift is to apply large droplets. Use the largest droplets that provide target pest control. While applying larger droplets will reduce spray drift, the potential for drift will be greater if applications are made improperly or under unfavorable environmental conditions. Controlling Droplet Size -Ground Boom x Volume - Increasing the spray volume so that larger droplets are produced will reduce spray drift. Use the highest practical spray volume for the application. If a greater spray volume is needed, consider using a nozzle with a higher flow rate. x Pressure - Use the lowest spray pressure recommended for the nozzle to produce the target spray volume and droplet size. x Spray Nozzle - Use a spray nozzle that is designed for the intended application. Consider using nozzles designed to reduce drift. Controlling Droplet Size –Aircraft x Adjust Nozzles -Follow nozzle manufacturers recommendations for setting up nozzles. Generally, to reduce fine droplets, nozzles should be oriented parallel with the airflow in flight. BOOM HEIGHT-Ground Boom For ground equipment, the boom should remain level with the crop and have minimal bounce. RELEASE HEIGHT – Aircraft Higher release heights increase the potential for spray drift. SHIELDED SPRAYERS Shielding the boom or individual nozzles can reduce spray drift. Consider using shielded sprayers. Verify that the shields are not interfering with the uniform deposition of the spray on the target area. TEMPERATURE AND HUMIDITY When making applications in hot and dry conditions, use larger droplets to reduce effects of evaporation. TEMPERATURE INVERSIONS Drift potential is high during a temperature inversion. Temperature inversions are characterized by increasing temperature with altitude and are common on nights with limited cloud cover and light to no wind. The presence of an inversion can be indicated by ground fog or by the movement of smoke from a ground source or an aircraft smoke generator. Smoke that layers and moves laterally in a

7 concentrated cloud (under low wind conditions) indicates an inversion, while smoke that moves upward and rapidly dissipates indicates good vertical air mixing. Avoid applications during temperature inversions. WIND Drift potential generally increases with wind speed. AVOID APPLICATIONS DURING GUSTY WIND CONDITIONS. Applicators need to be familiar with local wind patterns and terrain that could affect spray drift. Handheld Technology Applications: x Take precautions to minimize spray drift. USE DIRECTIONS FOR SPECIFIC CROPS Gem® RC Fungicide provides control or suppression of several important diseases of potatoes, rice, soybeans, and sugar beets. When reference is made to disease suppression, suppression can mean eith er erratic control from good to fair or consistent control at a level below that obtained with the best commercial disease control products. ROTATIONAL RESTRICTIONS Treated areas may be replanted immediately following harvest with any crop listed on this label. For crops not listed on this label, do not plant back within 30 days of last application. POTATOES Disease Control Rate fl. oz./Acre Application Timing Notes Early Blight (Alternaria solani) 2.9 to 3.8 Begin applications preventively and continue as needed on a 7-t o 1 0 -day spray schedule. Use the higher rates and shorter intervals when disease pressure is severe. Late Blight (Phytophthora infestans) Gem® RC Fungicide Tank Mixture: 3.8 Begin applications preventively. Alternate Gem® RC Fungicide (every other application) with a protectant fungicide for use against late blight on a 7- to 10-day spray schedule. Gem® RC Fungicide should always be applied in tank mixture with a registered protectant fungicide labeled for use on late blight (use 75% of the protectant fungicide labeled rate) and applied on a 7

• to 10- day spray schedule. Use the shorter interval when disease pressure is severe. Restrictions: Do not apply more than 23 fl. oz. of Gem® RC Fungicide per acre per season. Do not apply Gem® RC Fungicide within 7 days of harvest. To limit the potential for development of disease resistance: x Do not make more than one (1) foliar application of Gem ® RC Fungicide for foliar diseases before alternating to a labeled effective non-QoI fungicide with a different mode of action for at least one application. x Do not make more than six (6) applications of Gem® RC Fungicide or other QoI fungicides per season.

8 RICE Disease Control Rate fl. oz./Acre Application Timing Notes Sheath/Stem Diseases: Sheath Blight (Rhizoctonia solani) 3.8 to 4.7 Apply from panicle differentiation to boot split at initial sign of disease. Rate and timing for sheath blight is dependent on rice growth stage, rice variety and disease severity. Consult with your local extension personnel or Bayer CropScience representative to determine if treatment is needed. Use the higher rates when disease pressure is severe. Up to two applications can be made if conditions warrant. Panicle Diseases: Rice Blast (Pyricularia grisea) 3.1 to 4.7 Begin applications prior to disease development. For panicle blast, an application should be applied at mid

boot to 5% heading (tips of panicles just emerging) but prior to full head emergence. If conditions favor neck blast, a second application should be made when panicles are 60 to 90% emerged from the boot (5 to 14 days later). Consult with your local extension personnel or Bay er CropScience representative to determine the best timing for your area. Use the higher rates and shorter intervals when disease pressure is severe. Two applications are usually necessary for maximum control. Restrictions: Do not apply more than 9.4 fl. oz. of Gem® RC Fungicide per acre per crop. Do not apply Gem® RC Fungicide within 35 days of harvest. Do not apply in rice fields where commercial farming of crayfish will be practiced. Do not drain water from treated rice fields into ponds used for commercial catfish farming, to irrigate other crops, or use treated water for livestock. Do not allow release of irrigation or floodwater for at least 7 days after the last application. To limit the potential for development of disease resistance: x Do not make more than two (2) sequential applications of Gem® RC Fungicide. Then alternate to labeled, effective non-QoI fungicides with a different mode of action. x Do not make more than two (2) applications of Gem® RC Fungicide or other QoI fungicides per season.

9 SOYBEAN Disease Control Rate fl. oz/Acre Application Timing Notes Aerial blight (Rhizoctonia solani) Anthracnose (Colletotrichum truncatum) Alternaria leaf spot (Alternaria spp.) Asian soybean rust (Phakopsora spp.) Brown spot (Septoria glycines) Cercospora blight and leaf spot (Cercospora kikuchii) Frogeye leaf spot (Cercospora sojina) Pod & stem blight (Diaporthe phaseolorum) 3.0 to 3.5 Begin broadcast, foliar applications of Gem® RC Fungicide preventatively when conditions are favorable for disease development. Repeat applications on a 10-t o 2 1 -day spray interval if disease monitoring or environmental factors indicate favorable condi tions for continued disease development. Use the higher rates and shorter intervals when disease pressure is severe. Use of adjuvants may enhance performance of Gem® RC Fungicide. If utilized, apply the lowest recommended rate of the spray adjuvant. For control of Asian soybean rust, apply Gem® RC Fungicide prior to infection. If Asian soybean rust is already present in the field, Gem® RC Fungicide must be applied with an EPA-approved triazole fungicide with known curative activity. Applications may be made by ground or air. Apply Gem® RC Fungicide in a minimum for 10 gallons of spray solution per acre by ground sprayer or in a minimum of 2 gallons per acre by aircraft spray equipment. Restrictions: Do not apply more than 10.5 fl. oz. of Gem® RC Fungicide per acre per season. Applications may not be made within 21 days of harvest. Do not apply more than 2 applications of Gem® RC Fungicide or other Group 11 fungicides before alternating with a fungicide that is not in Group 11. Do not graze or feed soybean forage or hay. SUGAR BEETS Disease Control Rate fl. oz./Acre Application Timing Notes Foliar Diseases: Cercospora Leaf Spot (Cercospora beticola) Powdery Mildew (Erysiphe polygoni) 2.9 to 3.6 Begin applications preventively and continue as needed on a 10-t o 1 4 -day spray schedule. Alternate Gem® RC Fungicide after each application with a fungicide that has a different mode of action. Use the higher rates and shorter intervals when disease pressure is severe. May be applied via chemigation for control of powdery mildew. Soilborne Diseases: Disease Suppression Rhizoctonia Stem Canker, Root Rot, Crown Rot (Rhizoctonia solani) Begin either foliar broadcast or banded applications at the 4-leaf to row closure growth stage. Apply as needed on a 10- to 14-day spray schedule. Restrictions: Do not apply more than 10 fl. oz. of Gem® RC Fungicide per acre per season. Do not apply Gem® RC Fungicide within 21 days of harvest. To limit the potential for development of disease resistance: x One application of a Group 11 fungicide may be made up to the 4 leaf stage of plant growth. An additional Group 11 fungicide application may be made after the 4th leaf stage, but it must be alternated with at least one application of a fungicide from a different group before any additional applications of a Group 11 fungicide are allowed. x Do not make more than three (3) applications of Gem® RC Fungicide or other QoI fungicides per season.

10 IMPORTANT: READ BEFORE USE Read the entire Directions for Use, Conditions , Disclaimer of Warranties and Limitations of Liability before using this product . If terms are not acceptable, return the unopened product container at once. By using this product, user or buyer accepts the following Conditions, Disclaimer of Warranties and Limitations of Liability. CONDITIONS: The directions for use of this product are believed to be adequate and must be followed carefully. However, it is impossible to eliminate all risks associated with the use of this product. Crop injury, ineffectiveness or other unintended co nsequences may result because of such factors as weather conditions, presence of other materials, or the manner of use or application, all of which are beyond the control of Bayer CropScience. To the extent consistent with applicable law, a ll such risks shall be assumed by the user or buyer. DISCLAIMER OF WARRANTIES: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER CROPSCIENCE MAKES NO OTHER WARRANTIES, EXPRESS OR IMPLIE D, OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE OR OTHERWISE, THAT EXTEND BEYOND THE STATEMENTS MADE ON THIS LABEL. No agent of Bayer CropScience is authorized to make any warranties beyond those contained herein or to modi fy the warranties contained herein. TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER CROPSCIENCE DISCLAIMS ANY LIABILITY WHATSOEVER FOR SPECIAL, INCIDENTAL OR CONSEQUENTIAL DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT. LIMITATIONS OF LIABILITY: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE USER OR BUYER FOR ANY AND ALL LOSSES, INJURIES OR DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, WHETHER IN CONTRACT, WARRANTY, TORT, NEGLIGENCE, STRICT LIABILITY OR OTHERWISE, SHALL NOT EXCEED THE PURCHASE PRICE PAID, OR AT BAYER CROPSCIENCE’SELECTION, THE REPLACEMENT OF PRODUCT. Gem is a registered trademark of Bayer. NET CONTENTS: 2.5 GALLONS PRODUCED FOR Bayer CropScience LP 800 N. Lindbergh Blvd. St. Louis, MO 63167 1-866-99BAYER (1-866-992-2937) Gem RC Fungicide (PENDING) 06/03/2019, 06/06/2022, 06/14/2022, 05/19/2023, 07/10/2023, 07/12/2023, 07/24/2023