crop-chem-docs/corpus/epa_ppls/100-1690.md

CruiserMaxx(R) APX

• EPA Reg No: 100-1690
• Registrant: SYNGENTA CROP PROTECTION, LLC
• Signal word: Caution
• Active ingredients: Picarbutrazox (0.82%); Thiamethoxam (16.3%); Fludioxonil (0.82%); Metalaxyl-M (2.45%); Sedaxane (0.82%)
• Label accepted: 2021-09-30
• Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000100-01690-20210930.pdf

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Registration Notice Unconditional v.20150320

U.S. ENVIRONMENTAL PROTECTION AGENCY Office of Pesticide Programs Registration Division (7505P) 1200 Pennsylvania Ave., N.W. Washington, D.C. 20460

EPA Reg. Number:

100-1690

Date of Issuance:

9/30/21 NOTICE OF PESTICIDE: X Registration Reregistration

Term of Issuance: Unconditional (under FIFRA, as amended) Name of Pesticide Product: CruiserMaxx® APX

Name and Address of Registrant (include ZIP Code): Syngenta Crop Protection, LLC P.O. Box 18300 Greensboro, NC 27419

Note: Changes in labeling differing in substance from that accepted in connection with this registration must be submitted to and accepted by the Registration Division prior to use of the label in commerce. In any correspondence on this product always refer to the above EPA registration number.

On the basis of information furnished by the registrant, the above named pesticide is hereby registered under the Federal Insecticide, Fungicide and Rodenticide Act.

Registration is in no way to be construed as an endorsement or recommendation of this product by the Agency. In order to protect health and the environment, the Administrator, on his motion, may at any time suspend or cancel the registration of a pesticide in accordance with the Act. The acceptance of any name in connection with the registration of a product under this Act is not to be construed as giving the registrant a right to exclusive use of the name or to its use if it has been covered by others.

This product is unconditionally registered in accordance with FIFRA section 3(c)(5) provided that you:

1. Submit and/or cite all data required for registration/reregistration/registration review of your product when the Agency requires all registrants of similar products to submit such data.

2. The data requirements for storage stability and corrosion characteristics (Guidelines 830.6317 and 830.6320) are not satisfied. A one year study is required to satisfy these data requirements. You have 18 months from the date of registration to provide these data.

Signature of Approving Official:

Shaja B. Joyner, Product Manager 20 Fungicide-Herbicide Branch Registration Division 7505P

Date:

9/30/21 EPA Form 8570-6

Page 2 of 2 EPA Reg. No. 100-1690 Decision No. 572165

3. Make the following label changes before you release the product for shipment:

• Revise the EPA Registration Number to read, “EPA Reg. No. 100-1690.”

4. Submit one copy of the revised final printed label for the record before you release the product for shipment.

Should you wish to add/retain a reference to the company’s website on your label, then please be aware that the website becomes labeling under the Federal Insecticide Fungicide and Rodenticide Act and is subject to review by the Agency. If the website is false or misleading, the product would be misbranded and unlawful to sell or distribute under FIFRA section 12(a)(1)(E). 40 CFR 156.10(a)(5) list examples of statements EPA may consider false or misleading. In addition, regardless of whether a website is referenced on your product’s label, claims made on the website may not substantially differ from those claims approved through the registration process. Therefore, should the Agency find or if it is brought to our attention that a website contains false or misleading statements or claims substantially differing from the EPA approved registration, the website will be referred to the EPA’s Office of Enforcement and Compliance.

If these conditions are not complied with, the registration will be subject to cancellation in accordance with FIFRA section 6. Your release for shipment of the product constitutes acceptance of these conditions. A stamped copy of the label is enclosed for your records. Please also note that the record for this product currently contains the following CSFs:

• Basic CSF dated 01/25/2021 • Alternate CSFs 1 – 3 dated 01/25/2021

If you have any questions, please contact Lindsay DeMers via email at demers.lindsay@epa.gov.

Enclosure

CruiserMaxx APX Page 1 (Master label) THIAMETHOXAM GROUP 4A INSECTICIDE MEFENOXAM GROUP 4 FUNGICIDE SEDAXANE GROUP 7 FUNGICIDE FLUDIOXONIL GROUP 12 FUNGICIDE PICARBUTRAZOX GROUP U17 FUNGICIDE CruiserMaxx® APX [Alternate Brand Names: CruiserMaxx® APX Uncolored, Golden Harvest Preferred Seed Treatment] Engineered Fungicide-Insecticide Premix A seed treatment product for protection against early-season damage from listed insects, seed-borne diseases, and seedling diseases on soybean. Active Ingredients: Thiamethoxam 1 .....................................................................................................16.30% Mefenoxam2 ............................................................................................................2.45% Picarbutrazox3 .........................................................................................................0.82% Fludioxonil4 ..............................................................................................................0.82% Sedaxane5 ...............................................................................................................0.82% Other Ingredients: 78.79% Total: 100.00% 1CAS No. 153719-23-4 2CAS No. 70630-17-0 and CAS No. 69516-34-3 3CAS No. 500207-04-5 4CAS No. 131341-86-1 5CAS No. 874967-67-6 CruiserMaxx APX is a flowable concentrate for seed treatment containing 1.52 lb thiamethoxam, 0.23 lb mefenoxam, 0.08 lb picarbutrazox 0.08 lb fludioxonil and 0.08 lb sedaxane per gallon. KEEP OUT OF REACH OF CHILDREN. CAUTION See additional precautionary statements and directions for use in booklet. EPA Reg. No. 100- EPA Est. No.

Net Contents [Batch Code: _____ ] (For nonrefillables only.) 09/30/2021 100-1690

CruiserMaxx APX Page 2 TABLE OF CONTENTS 1.0 FIRST AID 2.0 PRECAUTIONARY STATEMENTS 2.1 Hazards to Humans and Domestic Animals 2.2 Personal Protective Equipment (PPE) 2.3 User Safety Requirements 2.4 Engineering Controls 2.5 User Safety Recommendations 2.6 Environmental Hazards 2.6.1 Groundwater Advisory 2.6.2 Pollinator Precautions 2.7 Physical or Chemical Hazards DIRECTIONS FOR USE 3.0 PRODUCT INFORMATION 3.1 Resistance Management 4.0 APPLICATION DIRECTIONS 4.1 Mixing Directions 4.1.1 Tank-Mix Precautions 4.1.2 Tank-Mix Compatibility 5.0 ROTATIONAL CROP RESTRICTIONS 6.0 RESTRICTIONS AND PRECAUTIONS 6.1 Use Restrictions 7.0 SEED CONTAINER LABEL REQUIREMENTS 8.0 CROP USE DIRECTIONS 8.1 Soybean 9.0 STORAGE AND DISPOSAL 10.0 CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY

CruiserMaxx APX Page 3 1.0 FIRST AID FIRST AID If swallowed x Call a poison control center or doctor immediately for treatment advice. x Have person sip a glass of water if able to swallow. x Do not induce vomiting unless told to do so by a poison control center or doctor. x Do not give anything by mouth to an unconscious person. If on skin or clothing x Take off contaminated clothing. x Rinse skin immediately with plenty of water for 15-20 minutes. x Call a poison control center or doctor for treatment advice. Have the product container or label with you when calling a poison control center or doctor, or going for treatment. HOTLINE NUMBER For 24-Hour Medical Emergency Assistance (Human or Animal) or Chemical Emergency Assistance (Spill, Leak, Fire, or Accident), Call 1-800-888-8372 2.0 PRECAUTIONARY STATEMENTS 2.1 Hazards to Humans and Domestic Animals CAUTION Harmful if swallowed or absorbed through the skin. Avoid contact with skin, eyes or clothing. Remove and wash contaminated clothing before reuse. Wash thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco or using the toilet. 2.2 Personal Protective Equipment (PPE) Applicators and other handlers must wear: x Long-sleeved shirt and long pants x Chemical-resistant gloves made of: EDUULHUODPLQDWHEXW\OUXEEHU•PLOVQLWULOHUXEEHU •PLOVQHRSUHQHUXEEHU•PLOVSRO\YLQ\OFKORULGH39&•PLOV9LWRQŠ•PLOV x Shoes plus socks 2.3 User Safety Requirements Follow the manufacturer’s instructions for cleaning/maintaining PPE. If no such instructions for washables exist, use detergent and hot water. Keep and wash PPE separately from other laundry.

CruiserMaxx APX Page 4 2.4 Engineering Controls When handlers use closed systems in a manner that meets the requirements listed in the Worker Protection Standard (WPS) for agricultural pesticides [40 CFR 170.240(d)(4-6)], the handler PPE requirements may be reduced or modified as specified in the WPS. 2.5 User Safety Recommendations Users should: x Wash hands before eating, drinking, chewing gum, using tobacco, or using the toilet. x Remove clothing/PPE immediately if pesticide gets inside. Then wash thoroughly and put on clean clothing. x Remove PPE immediately after handling this product. Wash the outside of gloves before removing. As soon as possible, wash thoroughly and change into clean clothing. 2.6 Environmental Hazards This product is toxic to wildlife, freshwater and estuarine/marine fish, oysters, and shrimp and highly toxic to aquatic invertebrates. Runoff may be hazardous to aquatic organisms in neighboring areas. Exposed treated seed may be hazardous to wildlife. Cover or collect treated seed spilled during loading and planting. DO NOT contaminate water when disposing of equipment washwater or rinsate. 2.6.1 Groundwater Advisory Mefenoxam is known to leach through soil into ground water under certain conditions as a result of label use. This chemical may leach into groundwater if used in areas where soils are permeable, particularly where the water table is shallow, and may result in groundwater contamination. Fludioxonil has properties and characteristics associated with chemicals detected in groundwater. This chemical may leach into groundwater if used in areas where soils are permeable, particularly where the water table is shallow, and may result in groundwater contamination. Thiamethoxam has properties and characteristics associated with chemicals detected in groundwater. This chemical may leach into groundwater if used in areas where soils are permeable, particularly where the water table is shallow, and may result in groundwater contamination. 2.6.2 Pollinator Precautions Thiamethoxam is highly toxic to bees and other pollinating insects, and effects are possible as a result of exposure to translocated residues in blooming crops.

CruiserMaxx APX Page 5 2.7 Physical or Chemical Hazards DO NOT use, pour, spill or store near heat or open flame. DO NOT store near or use with oxidizing agents. DO NOT mix or allow coming in contact with oxidizing agents. Hazardous chemical reaction may occur. DIRECTIONS FOR USE It is a violation of Federal Law to use this product in a manner inconsistent with its labeling. For use in commercial seed treatment facilities. Use is also permitted as an end-use seed treatment on agricultural establishments at planting, or immediately before planting, as specified in the Crop Use Directions. DO NOT apply this product in a way that will contact workers or other persons, either directly or through drift. Only protected handlers may be in the area during application. For any requirements specific to your State or Tribe, consult the State or Tribal agency responsible for pesticide regulation. DO NOT use for at-plant applications (including hopper box, planter box, etc.). This product is to be used in liquid or slurry treaters only. FAILURE TO FOLLOW THE DIRECTIONS FOR USE AND PRECAUTIONS ON THIS LABEL MAY RESULT IN CROP INJURY, POOR INSECT AND/OR DISEASE CONTROL, AND/OR ILLEGAL RESIDUES. AGRICULTURAL USE REQUIREMENTS Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR part 170. This Standard contains requirements for the protection of agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of agricultural pesticides. It contains requirements for training, decontamination, notification, and emergency assistance. It also contains specific instructions and exceptions pertaining to the statements on this label about personal protective equipment (PPE) and restricted- entry interval. The requirements in this box only apply to uses of this product that are covered by the Worker Protection Standard. DO NOT enter or allow worker entry into treated areas during the restricted-entry interval (REI) of 48 hours. Exception: If the seed is treated with the product and the treated seed is soil-injected or soil-incorporated, the Worker Protection Standard, under certain circumstances, allows workers to enter the treated area if there will be no contact with anything that has been treated. PPE required for early entry to treated areas that is permitted under the Worker Protection Standard and that involves contact with anything that has been treated, such as plants, soil, or water is: x Coveralls x Chemical-resistant gloves: EDUULHUODPLQDWHEXW\OUXEEHU•PLOVQLWULOHUXEEHU• PLOVQHRSUHQHUXEEHU•PLOVSRO\YLQ\OFKORULGH39&•PLOV9LWRQ•PLOV x Shoes plus socks

CruiserMaxx APX Page 6 Treatment of highly mechanically scarred or damaged seed or seed known to be of low vigor and poor quality may result in reduced germination and/or reduction of seed and seedling vigor. Treat a quantity of seed using equipment similar to that planned for treating the total seed lot. Prior to treatment, conduct germination tests on a portion of seed before committing the total seed lot to a selected seed treatment. Due to seed quality, crop or variety sensitivity, and seed storage conditions beyond the control of Syngenta, no claims are made to guarantee the germination of seed or propagating material for all crop seed when treated with CruiserMaxx APX. 3.0 PRODUCT INFORMATION CruiserMaxx APX is a seed treatment product containing the active ingredients thiamethoxam (insecticide) and fludioxonil, mefenoxam, picarbutrazox and sedaxane (fungicides). CruiserMaxx APX protects against damage from listed early-season insects, soil-borne and seed-borne diseases. Thiamethoxam is a systemic seed treatment insecticide belonging to the neonicotinoid class of chemistry. Thiamethoxam protects against listed chewing and sucking insects through contact and ingestion. Mefenoxam fungicide is active against Pythium, Phytophthora and systemic downy mildew. Picarbutrazox fungicide is active against Pythium and Phytophthora causing seed rot and damping-off. Fludioxonil fungicide is active against Fusarium and Rhizoctonia, and suppresses seed-borne Sclerotinia as well as provides protection from seed-borne Diaporthe-Phomopsis disease complex sometimes referred to as pod and stem blight (Phomopsis spp. & Diaporthe spp.). Fludioxonil also protects against Helminthosporium, and weakly pathogenic fungi such as Aspergillus and Penicillium. Sedaxane fungicide is active against seed decay, seedling blight and damping-off caused by Rhizoctonia species. 3.1 Resistance Management THIAMETHOXAM GROUP 4A INSECTICIDE For resistance management, CruiserMaxx APX contains thiamethoxam, a Group 4A insecticide. Any insect population may contain individuals naturally resistant to CruiserMaxx APX and other Group 4A insecticides. The resistant individuals may dominate the insect

CruiserMaxx APX Page 7 population if this group of insecticides are used repeatedly in the same fields. Appropriate resistance-management strategies should be followed. Thiamethoxam is a systemic insecticide belonging to the neonicotinoid class of chemistry which includes nicotinic acetylcholine receptor (nAChR) agonists. In order to maintain susceptibility to this class of chemistry: x Use products at their full, specified doses. x Use appropriate, well-maintained equipment. Use specified water volumes and apply at optimal temperatures in order to obtain optimal treatment. x When rate ranges are given, use the higher rate within the listed rate range when insect pressure is expected to be high. x Avoid using a single active ingredient or mode of action (same insecticide group) exclusively for season long control of insect species with more than one generation per crop season. x For insect species with successive or overlapping generations, use a treatment window approach. A treatment window is a period of time defined by the stage of crop development and the biology of the pests of concern. Within the treatment window, depending on the length of residual activity, single or consecutive applications may be made using seed, in-furrow, or foliar treatments unless otherwise excluded by product labels. DO NOT exceed the maximum amount of this insecticide’s mode of action allowed per growing season. x Following a treatment window of this insecticide’s mode of action, rotate to a treatment window of effective products with a different mode of action before making additional applications of this insecticide. Syngenta encourages responsible product stewardship to ensure effective long-term protection from the insect pests on this label. For additional information on Insect Resistance Management: x Contact Syngenta representatives at 1-800-334-9481. x Contact your local Cooperative Extension Service specialist, pest control advisor, or certified crop advisor. x Visit the Insecticide Resistance Action Committee (IRAC) on the web at: http://www.irac- online.org. MEFENOXAM GROUP 4 FUNGICIDE SEDAXANE GROUP 7 FUNGICIDE FLUDIOXONIL GROUP 12 FUNGICIDE PICARBUTRAZOX GROUP U17 FUNGICIDE For resistance management, please note that CruiserMaxx APX contains Group 4/mefenoxam, Group 7/sedaxane, Group 12/fludioxonil and Group U17/picarbutrazox fungicides. Any fungal population may contain individuals naturally resistant to CruiserMaxx APX and other Group 4, Group 7, Group 12 and Group U17 fungicides. A gradual or total loss of pest control may occur over time if these fungicides are used repeatedly in the same fields. Appropriate resistance-management strategies should be followed.

CruiserMaxx APX Page 8 To delay fungicide resistance, take one or more of the following steps: x Rotate the use of CruiserMaxx APX or other Group 4, Group 7, Group 12 or Group U17 fungicides within a growing season sequence with different groups that control the same pathogens. x Use tank mixtures with fungicides from a different group that are equally effective on the target pest when such use is permitted. Use at least the minimum application rate as labeled by the manufacturer. x Adopt an integrated disease management program for fungicide use that includes scouting, uses historical information related to pesticide use, and crop rotation, and which considers host plant resistance, impact of environmental conditions on disease development, disease thresholds, as well as cultural, biological and other chemical control practices. x Where possible, make use of predictive disease models to effectively time fungicide applications. Note that using predictive models alone is not sufficient to manage resistance. x Monitor treated fungal populations for resistance development. x Contact your local extension specialist or certified crop advisor for any additional pesticide resistance-management and/or IPM recommendations for specific crop and pathogens. x For further information or to report suspected resistance contact Syngenta at 1-866- Syngent(a) (866-796-4368). You can also contact your pesticide distributor or university extension specialist to report resistance. Syngenta encourages responsible product stewardship to ensure effective long-term control of the fungal diseases on this label. For additional information on Fungicide Resistance Management: x Contact Syngenta representatives at 1-800-334-9481. x Contact your local extension specialist or certified crop advisor. x Visit the Fungicide Resistance Action Committee (FRAC) on the web at: http://www.frac.info . 4.0 APPLICATION DIRECTIONS 4.1 Mixing Directions Important: Always re-circulate CruiserMaxx APX thoroughly before using. The typical density of CruiserMaxx APX is 9.35 pounds per gallon. Consult the manufacturer of the application equipment you plan to use for suitability for this application and for instructions on operation and calibration of the equipment. Follow the manufacturer application instructions for the seed treatment equipment being used. Apply CruiserMaxx APX as a water-based slurry utilizing standard slurry seed treatment equipment which provides uniform seed coverage. Uneven or incomplete seed coverage may not give the desired level of disease control. Thoroughly mix the specified amount of

CruiserMaxx APX Page 9 CruiserMaxx APX into the required amount of water or liquid inoculant for the slurry treater and dilution rate to be used. Certain crops require addition of inoculants when the seed is treated or planted. CruiserMaxx APX is compatible with several liquid inoculant products. Consult the maker of the inoculant product and a Syngenta representative for directions before applying CruiserMaxx APX with inoculants. The total application volume must be sufficient to provide desired level of coverage. Dilution is typically done with water or liquid inoculants. The minimum slurry volume to achieve adequate coverage is 4.0 fluid ounces per 100 pounds of seed. More diluent may be required to obtain complete coverage. Continuous agitation or mixing of the slurry mixture is necessary to prevent settling out of the solution. Allow seed to dry before bagging. Follow planter manufacturer specifications for use of talc or other hopper box additives at planting. Seed must be completely dry before adding to planter. Use an EPA approved dye/colorant that imparts an unnatural color to the seed as required in 40CFR 153.155(c). 4.1.1 Tank-Mix Precautions Mixing CruiserMaxx APX with tank-mix partners: Add 1/2 of the required water to the mix tank and turn on the agitation. Mechanical agitation is preferred. Follow WALES method for mixing order of seed treatment products. Allow each tank-mix partner to completely disperse before adding the next product. Add the remaining amount of water and agitate. Maintain agitation until the entire slurry mixture has been used. Continuous agitation or mixing of the slurry mixture is necessary to prevent settling out of the solution. Clean out any unused product from the treater after treating or maintain constant agitation if the leftover slurry will be maintained overnight. It is the pesticide user’s responsibility to ensure that all products are registered for the intended use. Read and follow the applicable restrictions and limitations and directions for use on all product labels involved in tank mixing. Users must follow the most restrictive directions for use and precautionary statements of each product in the tank mixture. 4.1.2 Tank-Mix Compatibility When mixing CruiserMaxx APX with other seed treatment products, test the compatibility prior to use by conducting a jar test: mix all intended seed treatments with the appropriate amount of water in a clear glass container. Mix well and allow mixture to sit for one hour. Remix and observe for incompatibility.

CruiserMaxx APX Page 10 5.0 ROTATIONAL CROP RESTRICTIONS x In the event of crop failure or harvest of a crop grown from seed treated with CruiserMaxx APX, the field may be replanted according to the following schedule: Plantback Interval Table Immediate Plantback Minimum 30-Day Plantback Interval Corn (Field, Pop, Sweet) Soybean Alfalfa Canola Cereal Grains Crop Group 15 Cotton Cucurbit Vegetables Crop Group 9 Dried Shelled Pea and Bean (except soybean) Crop Group 6C Fruiting Vegetables Crop Group 8 Head and Stem Brassica Crop Subgroup 5A Leafy Brassica Greens Crop Subgroup 5B Leafy Vegetables Crop Group 4 Legume Vegetables (Succulent or Dried) Crop Group 6 Mint: Peppermint and Spearmint Oilseeds: Borage, Crambe, Flax Seed, and Mustard Seed Onion, Dry Bulb Peanut Potato Root Vegetables Crop Subgroup 1A Safflower Strawberry Sugarbeet Sunflower Tobacco Tuberous and Corm Vegetables (Except Potato) Crop Subgroup 1D

CruiserMaxx APX Page 11 x For any other crops the minimum plant back interval is 120 days from the date the soybean seeds treated with CruiserMaxx APX were planted. A cover crop other than the crops listed above that is planted for erosion control or soil improvement may be planted sooner than the 120-day interval; however, the crop may not be grazed or harvested for food or feed. 6.0 RESTRICTIONS AND PRECAUTIONS 6.1 Use Restrictions Maximum usage when applying both metalaxyl- and mefenoxam-containing products to the same crop within the same season: DO NOT apply more than the maximum seasonal total for the active ingredient as stated on the label of the product containing the lowest seasonal total on that crop. DO NOT use at a rate that will result in more than 0.266 lb thiamethoxam per acre (120 grams ai/A) per calendar year, regardless of type of application (seed treatment and/or foliar). DO NOT use at a rate that will result in more than 0.083 lb thiamethoxam per acre (37.8 grams ai/A) per calendar year as a seed treatment application. This seed has been treated with 0.0756 mg ai thiamethoxam per seed. DO NOT apply more than 0.004 lb (2.0 g) of fludioxonil per acre per calendar year as a seed treatment. This seed has been treated with 0.0039 mg ai fludioxonil per seed. DO NOT apply more than 0.013 lb (5.7 g) of mefenoxam per acre per calendar year as a seed treatment. This seed has been treated with 0.0114 mg ai mefenoxam per seed. DO NOT apply more than 0.004 lb (2.0 g) of sedaxane per acre per calendar year as a seed treatment. This seed has been treated with 0.0039 mg ai sedaxane per seed. DO NOT apply more than 0.004 lb (2.0 g) of picarbutrazox per acre per calendar year as a seed treatment. This seed has been treated with 0.0039 mg ai picarbutrazox per seed. DO NOT plant more than 250,000 soybean seed per acre. DO NOT apply a neonicotinoid insecticide within 45 days of planting seed treated with CruiserMaxx APX. This treated seed may be planted on the same acres up to 2 times per year. DO NOT use for feed, food, or oil purposes. Use an EPA approved dye/colorant that imparts an unnatural color to the seed as required in 40CFR 153.155(c). DO NOT allow children, pets, or livestock to have access to treated seed. Store away from feed and foodstuffs.

CruiserMaxx APX Page 12 Treated seed must be planted into the soil at a depth greater than 1 inch. Excess treated seed may be used for ethanol production only if (1) by-products are not used for livestock feed and (2) no measurable residues of pesticide remain in the ethanol by- products that are used in agronomic practice. 7.0 SEED CONTAINER LABEL REQUIREMENTS The Federal Seed Act requires that bags containing treated seeds shall be labeled with the following statements: x This seed has been treated with thiamethoxam insecticide and fludioxonil, mefenoxam, picarbutrazox and sedaxane fungicides. x DO NOT use for feed, food, or oil purposes. x User is responsible for ensuring that the seed bag meets all requirements under the Federal Seed Act. x Use an EPA approved dye/colorant that imparts an unnatural color to the seed as required in 40CFR 153.155(c). In addition, the U.S. Environmental Protection Agency requires the following statements on bags containing seeds treated with CruiserMaxx APX: x Ground Water Advisory: Mefenoxam is known to leach through soil into ground water under certain conditions as a result of agricultural use. Fludioxonil and Thiamethoxam have properties and characteristics associated with chemicals detected in ground water. Mefenoxam, Fludioxonil, and Thiamethoxam may leach into groundwater if used in areas where soils are permeable, particularly where the water table is shallow. x Pollinator Precautions: Thiamethoxam is highly toxic to bees and other pollinating insects, and effects are possible as a result of exposure to translocated residues in blooming crops. x Excess treated seed may be used for ethanol production only if (1) by-products are not used for livestock feed and (2) no measurable residues of pesticide remain in the ethanol by-products that are used in agronomic practice. x DO NOT allow children, pets, or livestock to have access to treated seed. x Store away from feed and foodstuffs. x Wear long-sleeved shirt, long pants and chemical resistant gloves when handling treated seed. x Treated seeds exposed on soil surface may be hazardous to wildlife. Cover or collect treated seeds spilled during loading. x Treated seed must be planted into the soil at a depth greater than 1 inch. x Dispose of all excess treated seed. Leftover treated seed may be double sown around the headland or buried away from water sources in accordance with local requirements. x DO NOT contaminate water bodies when disposing of planting equipment wash waters. x Dispose of seed packaging in accordance with local requirements. x In the event of crop failure or harvest of a crop grown from seed treated with CruiserMaxx APX, the field may be replanted according to the following schedule:

CruiserMaxx APX Page 13 Plantback Interval Table Immediate Plantback Minimum 30-Day Plantback Interval Corn (Field, Pop, Sweet) Soybean Alfalfa Canola Cereal Grains Crop Group 15 Cotton Cucurbit Vegetables Crop Group 9 Dried Shelled Pea and Bean (except soybean) Crop Group 6C Fruiting Vegetables Crop Group 8 Head and Stem Brassica Crop Subgroup 5A Leafy Brassica Greens Crop Subgroup 5B Leafy Vegetables Crop Group 4 Legume Vegetables (Succulent or Dried) Crop Group 6 Mint: Peppermint and Spearmint Oilseeds: Borage, Crambe, Flax Seed, and Mustard Seed Onion, Dry Bulb Peanut Potato Root Vegetables Crop Subgroup 1A Safflower Strawberry Sugarbeet Sunflower Tobacco Tuberous and Corm Vegetables (Except Potato) Crop Subgroup 1D x For any other crops the minimum plant back interval is 120 days from the date the seeds treated with CruiserMaxx APX were planted. A cover crop other than the crops listed above that is planted for erosion control or soil improvement may be planted sooner than the 120-day interval; however, the crop may not be grazed or harvested for food or feed. x DO NOT use at a rate that will result in more than 0.266 lb thiamethoxam per acre (120 grams ai/A) per calendar year, regardless of type of application (seed treatment and/or foliar). DO NOT use at a rate that will result in more than 0.083 lb thiamethoxam per acre (37.8 grams ai/A) per calendar year as a seed treatment

CruiserMaxx APX Page 14 application. DO NOT apply more than 0.004 lb (2.0 g) of fludioxonil per acre per calendar year as a seed treatment. DO NOT apply more than 0.013 lb (5.7 g) of mefenoxam per acre per calendar year as a seed treatment. DO NOT apply more than 0.004 lb (2.0 g) of sedaxane per acre per calendar year as a seed treatment. DO NOT apply more than 0.004 lb (2.0 g) of picarbutrazox per acre per calendar year as a seed treatment. x This seed has been treated with 0.0756 mg ai thiamethoxam, 0.0039 mg ai fludioxonil, 0.0114 mg ai mefenoxam, 0.0039 mg ai sedaxane, and 0.0039 mg ai picarbutrazox per seed. x DO NOT plant more than 250,000 soybean seed per acre. x DO NOT apply a neonicotinoid insecticide within 45 days of planting seed treated with CruiserMaxx APX. This treated seed may be planted on the same acres up to 2 times per year. 8.0 CROP USE DIRECTIONS When applied according to the CruiserMaxx APX Rate Table, CruiserMaxx APX provides early season protection against injury by aphids, bean leaf beetle, grape colaspis, leaf miners, leaf hoppers, Mexican bean beetle, seed corn maggot, three-cornered alfalfa hopper, thrips, white grubs, and wireworm. CruiserMaxx APX also provides protection against damping-off and seed borne rots due to Pythium, Phytophthora, Fusarium, Rhizoctonia species and early season Phytophthora root rot as well as Anthracnose on soybean caused by seed-borne Colletotrichum spp. CruiserMaxx APX also provides protection from seed-borne Diaporthe-Phomopsis disease complex sometimes referred to as pod and stem blight (Phomopsis spp. & Diaporthe spp.), Helminthosporium, and weakly pathogenic fungi such as Aspergillus and Penicillium. Additional Apron XL® or similar fungicide may be necessary for high levels of Phytophthora or Pythium. Read and follow all label direction for Apron XL use. It is the pesticide user's responsibility to ensure that all products in a tank mix are registered for the intended use. Users must follow the most restrictive directions and precautionary language of the products of the mixture (for example, first aid from one product, REI from another).

CruiserMaxx APX Page 15 8.1 Soybean CruiserMaxx APX Rate Table Crop Rate of CruiserMaxx APX Soybean fl oz per 100 lb seed1 or fl oz per 140,000 seeds1 grams ai per 100 kg seed mg ai per seed 4.18 fl oz per 100 lb seed or 1.95 fl oz per 140,000 seeds Thiamethoxam 50 gm Picarbutrazox 2.6 gm Mefenoxam 7.5 gm Fludioxonil 2.6 gm Sedaxane 2.6 gm Total = 65.3 gm Total of all active ingredients = 0.0983 mg 1The mg ai per seed, fl oz CruiserMaxx APX per 100 lb seed, and fl oz CruiserMaxx APX per 140,000 seeds rates are based on 3,000 soybean seeds per pound. STORED GRAIN PROTECTION When treated according to the directions for post-planting protection against listed pests, CruiserMaxx APX will also provide protection during post treatment storage of the seed listed on this label against damage from the following stored grain insects: Indian Meal Moth (Plodia interpunctella), Rice Weevil (Sitophilus oryza), Red Flour Beetle (Tribolium castaneum), and Lesser Grain Borer (Rhizopertha dominica). If the seed to be treated has existing infestations of stored grain insects, fumigate the seed with a registered product approved for such use prior to treating with CruiserMaxx APX and bagging. 9.0 STORAGE AND DISPOSAL STORAGE AND DISPOSAL DO NOT contaminate water, food, or feed by storage or disposal. Pesticide Storage Store in the original container and only in a cool, dry, secure place. Store between a range of 32°F to 100°F. For minor spills, leaks, etc., follow all precautions indicated on this label and clean up immediately. Take special care to avoid contamination of equipment and facilities during cleanup procedures and disposal of wastes.

CruiserMaxx APX Page 16 Pesticide Disposal Wastes resulting from the use of this product must be disposed of on site or at an approved waste disposal facility. If these wastes cannot be disposed of by use according to label instructions, contact your State Pesticide or Environmental Control Agency, or the Hazardous Waste Representative at the nearest EPA Regional Office for guidance. Container Handling [less than or equal to 5 gallons] Non-refillable container. DO NOT reuse or refill this container. Triple rinse container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank and drain for 10 seconds after the flow begins to drip. Fill the container ¼ full with water and recap. Shake for 10 seconds. Pour rinsate into application equipment or a mix tank or store rinsate for later use or disposal. Drain for 10 seconds after the flow begins to drip. Repeat this procedure two more times. Then offer for recycling if available or puncture and dispose of in a sanitary landfill, or by incineration, or by other procedures approved by state and local authorities. Container Handling [greater than 5 gallons] Non-refillable container. DO NOT reuse or refill this container. Triple rinse container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank. Fill the container ¼ full with water. Replace and tighten closures. Tip container on its side and roll it back and forth, ensuring at least one complete revolution, for 30 seconds. Stand the container on its end and tip it back and forth several times. Turn the container over onto its other end and tip it back and forth several times. Empty the rinsate into application equipment or a mix tank or store rinsate for later use or disposal. Repeat this procedure two more times. Then offer for recycling if available or puncture and dispose of in a sanitary landfill, or by incineration, or by other procedures approved by state and local authorities. Container Handling [greater than 5 gallons] Refillable container. Refill this container with pesticide only. DO NOT reuse this container for any other purpose. Cleaning the container before final disposal is the responsibility of the person disposing of the container. Cleaning before refilling is the responsibility of the person refilling. To clean container before final disposal, empty the remaining contents from this container into application equipment or mix tank. Fill the container about 10 percent full with water. Agitate vigorously or recirculate water with the pump for 2 minutes. Pour or pump rinsate into application equipment or rinsate collection system. Repeat this rinsing procedure two more times. Then offer for recycling if available or puncture and dispose of in a sanitary landfill, or by incineration, or by other procedures approved by state and local authorities. CONTAINER IS NOT SAFE FOR FOOD, FEED, OR DRINKING WATER.

CruiserMaxx APX Page 17 10.0 CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY NOTICE: Read the entire Directions for Use and Conditions of Sale and Limitation of Warranty and Liability before buying or using this product. If the terms are not acceptable, return the product at once, unopened, and the purchase price will be refunded. The Directions for Use of this product must be followed carefully. It is impossible to eliminate all risks inherently associated with the use of this product. Crop injury, ineffectiveness or other unintended consequences may result because of such factors as manner of use or application, weather or crop conditions, presence of other materials or other influencing factors in the use of the product, which are beyond the control of SYNGENTA CROP PROTECTION, LLC or Seller. To the extent permitted by applicable law, Buyer and User agree to hold SYNGENTA and Seller harmless for any claims relating to such factors. SYNGENTA warrants that this product conforms to the chemical description on the label and is reasonably fit for the purposes stated in the Directions for Use, subject to the inherent risks referred to above, when used in accordance with directions under normal use conditions. To the extent permitted by applicable law: (1) this warranty does not extend to the use of the product contrary to label instructions, or under conditions not reasonably foreseeable to or beyond the control of Seller or SYNGENTA, and (2) Buyer and User assume the risk of any such use. TO THE EXTENT PERMITTED BY APPLICABLE LAW, SYNGENTA MAKES NO WARRANTIES OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE NOR ANY OTHER EXPRESS OR IMPLIED WARRANTY EXCEPT AS WARRANTED BY THIS LABEL. To the extent permitted by applicable law, in no event shall SYNGENTA be liable for any incidental, consequential or special damages resulting from the use or handling of this product. TO THE EXTENT PERMITTED BY APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE USER OR BUYER, AND THE EXCLUSIVE LIABILITY OF SYNGENTA AND SELLER FOR ANY AND ALL CLAIMS, LOSSES, INJURIES OR DAMAGES (INCLUDING CLAIMS BASED ON BREACH OF WARRANTY, CONTRACT, NEGLIGENCE, TORT, STRICT LIABILITY OR OTHERWISE) RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, SHALL BE THE RETURN OF THE PURCHASE PRICE OF THE PRODUCT OR, AT THE ELECTION OF SYNGENTA OR SELLER, THE REPLACEMENT OF THE PRODUCT. SYNGENTA and Seller offer this product, and Buyer and User accept it, subject to the foregoing Conditions of Sale and Limitation of Warranty and Liability, which may not be modified except by written agreement signed by a duly authorized representative of SYNGENTA. Apron XL®, CruiserMaxx®, the ALLIANCE FRAME, the SYNGENTA Logo, and the PURPOSE ICON are Trademarks of a Syngenta Group Company Viton® trademark of E. I. du Pont de Nemours & Company, Inc.

CruiserMaxx APX Page 18 ©20XX Syngenta For non-emergency (e.g. current product information), call Syngenta Crop Protection at 1-800-334-9481. Manufactured for: Syngenta Crop Protection, LLC P.O. Box 18300 Greensboro, North Carolina 27419-8300 CruiserMaxx APX NEW C FEB2021 – CL – jeb – 09/28/2021 000100-XXXXX.20210205C.CRUISERMAXX_APX_NEW_0221-CL.pdf