crop-chem-docs/corpus/epa_ppls/100-942.md

ADAGE 70WS INSECTICIDE

• EPA Reg No: 100-942
• Registrant: SYNGENTA CROP PROTECTION, LLC
• Signal word: Caution
• Active ingredients: Thiamethoxam (70%)
• Label accepted: 2000-12-04
• Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000100-00942-20001204.pdf

---

/6J--'/- C,S. E~'1RONME~'T.-\L PRiOTECTION-AGE~~'CY~~~~=E=P=A=R=,g=. =N""'=bc<=, =r=D=.="=o=rho=wn====="i1J I Offi of Pesticide Programs R,g;,tr.ti= "";,;on (H7505C) 100-942 DEC 2fJl) 401 .~f" St, S.W. Washing1on, D.C. 20460 NOTICE OF PESTICIDE: ..L Registration Tom> orho""",,, Conditional Name of Pesticide Product: ." FlFRA. "" Reregistration ( .... tuer as amcnucu) - Adage ™ 70WS Insecticide Name and Address of Registrant (include ZIP Codel: Syngenta Crop Protection, Inc. P.O. Box 18300 Greensboro, NC 27419-8300 On the basis of information furnished by the registrant. the above named pesticide is hereby registered/reregistered under the Federal Insecticide. Fungicide and Rodenticide Act. Registration is in no way to be construed as an endorsement or recommendation of this product by the Agency. In order to protect health and the environment, the Administrator. on his motion. may at any time suspend or cancel the registration 01 a pesticide in accordance with the Act. The acceptance of any name in connection with the registration of a product under this Act is not to be construed as giving the registrant a right to exclusive use of the name or to its use if it has been covered by others. This product is conditionally registered in accordance with FIFRA sec. 3(c)(7)(C). provided that you submit the following data and label revisions: .

1. Submit and/or cite all data required for registration/registration review of your product when the Agency requires all registrants of similar products to submit such data.
2. Before you release the product for shipment revise the EPA Registration number to read "EPA Reg. No. 100-942 ".
3. Submit the following information to satisfy the data gaps in the data base for Thiamethoxam and its metabolite. The following information is required within 15 months of the date of this Notice: Residue Chemistry: 860.1340: 860.1380: 860.1480: 860.1900 860.1300: 860.1300: Modification of Method AG-675 to add microwave extraction ofliver or a new enforcement method for liver; additional radiovalidation data for beef liver Storage stability data continued to cover the conditions and intervals that plant and animal commodity samples were stored (up to 30 months) Reanalysis of the cow liver samples from the feeding study using a microwave extraction step Reanalysis offield rotational crop samples for metabolite CGA-265307 and description of storage conditions for future uses Plant metabolism study on a leafy vegetable (Crop Group 4 or 5) Poultry metabolism study
4. Submit the following information to satisfY the data gaps in the data base for Thiamethoxam and its metablolite. The follo"ing infonnation is required "ithin two years of the date of this Notice: Signature of Approving Official: Date: OEC 4 2DOO

2 EPA fonn 8570-6 (EPA reg. No. 100-942) continued from page 1... Toxicology Data: 870.6300: Developmental neurotoxicity study. Ecological Effects 72-4b: Daphnia chronic study repeated to fulfill guideline requirements 5. Submit two (2) copies of your final printed label for before your release tbe product for shipment. Please refer to the A-79 enclosure for a further description of final printed labeling. Iftbese conditions are not complied witb, the registration will be subject to cancellation in accordance witb FIFRA section 6(e). Your release for shipment oftbe product bearing amended labeling constitutes acceptance of tbese conditions. A stamped copy of tbe label is enclosed for your records. A stamped copy of tbe label is enclosed for your records. If you have any questions regarding this action, please contact Dani Daniel at 703 305-5409. Sincerely, Kerry Leifer, Acting Chief Insecticide-Rodenticide Branch Registration Division (7504C)

------- ...... -.-- 2 EPA Conn 8570-6 (EPA reg. No.1 00-942) continued from page L. Toxicology Data: 870.6300: Developmental neurotoxicity study. Ecological Effects 72-4b: Daphnia chronic study repeated to fulfill guideline requirements 5. Submit two (2) copies of your final printed label for before your release the product for shipment. Please refer to the A-79 enclosure for a further description of final printed labeling. If these conditions are not complied with, the registration "ill be subject to cancellation in accordance with FIFRA section 6(e). Your release for shipment of the product bearing amended labeling constitutes acceptance of these conditions. A stamped copy of the label is enclosed for your records. A stamped copy of the label is enclosed for your records. If you have any questions regarding this action, please contact Darti Daniel at 703 305-5409. Sincerely, Kerry Leifer, Acting Chief Insecticide-Rodenticide Branch Registration Division (7504C)

----------.==--=.-.. ---- ... __ . Adage"! 70WS INSECTICIDE (11/30/00) (Water Soluble Bags) A seed treatment product for control of certain insects on barley, cotton, sorghum and wheat Active Ingredient: Th,amethoxam: (CAS ?\Io. 153719-23-4) ........................ . . .. 70% Other Ingredients: 30% Total: 100.00% Adage 70WS is packaged in I pound water soluble pouches. EPA Reg. '-.'0. 100- , KEEP OUT OF REACH Of CHILDREN, CAUTIO"" See storage, disposal. and precautionary statements and directions for use inside booklet. L.S Standard \easure :-';CP ACCEPTED , with COMMENTS In EPA Letter Dated: I bEe.. -4 .:kDOO Vockr l!.e f;-dd·,'.i· Il'._·,·'.i:idt'. Fungicide, UP:: r.};: .- . .', ", .. ru:;.:rrl,· :' . . ' ;. ~ re,pkr, . ..lOfHW- _

DIRECTIONS FOR USE AND CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY ;liOTleE: Read the entire Directions for Use and Conditions of Sale and Limitation of Warranty and LiabilJlY before buying or using this product. If the terms are not acceptable, return the product at once, unopened. and the purchase price will be refunded. The Directions for l'se of this product should be followed carefully. It is impossible to eliminate all flSks inherently associated with the use of this product. Crop inJUry, ineffectiveness or other unintended consequences may result because of such factors as manner of use or application. weather or crop condJltons. presence of other materials or other influencing factors in the use of the product, which are beyond the control of Novartis Crop Protection, Inc. or Seller. All such risks shall be assumed by Buyer and User, and Buyer and User agree to hold Novartis and Seller harmless for any claims relating to such factors. ];ovartis warrants that this product conforms to the chemical description on the label and is reasonably fit for the purposes stated in the Directions for Use, subject to the inherent risks referred (0 above. when used in accordance with directions under nonnal use conditions. This warranty does not extend to<h~ use of.the product contrary to label instructiMs, or under abnoffiJal coo.ditioll&or ucter cQndition' notn;onably foreseeabl to or beond the contro~ of .':Selleror Novartis, and BUyer and Uso:r assl\l11etherisk otani' such'!ise: Novarti~ M,;\KES NO ··WARRANfIES OF MERCHANTABILrrY {)ROF FITNESS FORA PARTICULAR . PURPOSE NOR Al'Y OTHER EXPRESS OR IMPLIED W ARRA:-.ITY EXCEPT AS STA TED ABOVE In no event shall NO\·artis or Seller be liable for any incidental. consequential or special damages resulting from the use or handling of this product. THE EXCLUSIVE REMEDY OF THE USER OR BUYER. AND THE EXCLUSIVE LIABILITY OF NOV ARTIS AND SELLER FOR ANY AND ALL CLAI~IS. LOSSES, lNJlRlES OR DAMAGES (lNCLUDI:-.IG CLAIMS BASED ON BREACH OF WARRANTY. CONTRACT, NEGLIGENCE TORT. STRlCT LIABILITY OR OTHERWISE) RESULTING FROM THE USE OR HANDLI:-.IG OF THIS PRODUeT, SH.\LL BE THE RETCRt'l OF THE PURCHASE PRlCE OF THE PRODUCT OR. AT THE ELECTIO]; OF NO\·.\RTIS OR SELLER. THE REPLACE\IEl\T OF THE PRODUCT. No,ortis and Seller offer this product. and Buyer and Cser accept II. subject to the foreg,'mg condilions of sale and limitations of warranty and of liability. ,,·hlch may not be modified except by written agreement signed by a duly authorized representative of ~ovartis. fJ/rr " '

DIRECTIONS FOR USE It is a violation of federal law to use this product in a manner inconsistent with its labeling, AGRlCUL TURAL USE REQUIREMENTS Lse this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR pan 170, This Standard contains requirements for the protection of agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of agricultural pesticides, It contains requirements for training, decontamination, notification, and emergency assistance, It also contains specific instructions and exceptions penaining to the statements on this label about persl,nal protective equipment (PPE) and restricted-entry interval. The requirements in this box only apply to uses of this product that are covered by the Worker Protection Standard, Do not enter or allow worker entry into treated areas during Ie restricted entry iDterva) (REI) of 1,2 burs; Exception; If the s~~d istr!ated with Ihe product an~ th~ , _ , treated seed'is soiT mje'cted onot\ incorporated, the Weirker Protection Standanl, undr , certain circumstances: alieiws workers to enter the treated a'rea if there will 'be no contact with anything that has been treated, PPE required for early entry to treated areas that is permitted under the Worker Protection Standard and that involves contact with anY1hing that has been treated, such as plants. I soil. or water is: • Coveralls • Waterproof gloves • Shoes plus soeks FAILURE TO fOLLOW THE DIRECTlO\S fOR USE ,:,\D PRECAUTIONS 0' THIS LABEL MA Y RESULT IN CROP I:'IIJURY, POOR Ii\SECT AND/OR DISEASE CO\TROL, A:'IiD/OR ILLEGAL RESIDUES. Treatment of highly mechanically scarred or damaged seed or seed known to be of low vigor and poor quality may result in reduced germination and'or reduction of seed and seedling vigor. Treat a small quantity of seed using equipment similar to that planned for treating the total seed lot. Conduct germination tests on a small ponion 'of seed before committmg the total seed lot to a selected seed treatment. Due to seed quality and seed swrage conditions beyond the control of\ov'anis, no claims are made to guarantee the germination of carry-over seed or propagating material for all crop seed,

GENERAL INFORMA nON Adage 70WS is a systemic seed treatment insecticide belonging to the neonicotinoid class of chemistry. Adage 70WS controls certain chewing and sucking insects following contact and ingestion. When rate ranges are given. use higher rates when insect pressure is expected to be high. :\lixing Procedures Adage 70WS is a wettable powder fonnulated especially for seed treatment uses. Apply Adage 70WS as a water based slurry utilizing standard slurry seed treattnent equipment which provides unifonn seed coverage. Cneven or incomplete seed coverage may not give the desired level of insect control. Thoroughly mix the recommended amount of Adage 70WS into the required amount of water for the slurry treater and dilution rate to be used. One pound of Adage 70WS displaces II fl. oz of water. Consult the manufacturer of the application equipment You plan to use for suitability for this application and for Instructions on operati()n and calibration of the equipment. Allow . ,seed. to dry. before:bagging. . . . ' .. ' ' . .... ". Federallaw'"requires 'that'bags'containirtgtreate<.1 ~eed 'shali be 'labeled witli the following infonnation: "This seed has been treated WIth thiamethoxam insecticide. Do not use for feed. food. or oil purposes. Store away from feed and foodstuffs. "Use an EPA·approved dye or colorant that imparts an unnatural color to the seed. BARLEY To provide early season protection of seedlings against injury by bird cherry-oat aphid, English grain aphid. Russian wheat aphid. greenbug. HeSSIan fly. and wirewonn and to reduce potential spread of barley yellow dwarf virus due to the aphid vectors mentioned above. apply Adage 70WS at 0.66-1.2 oz. per 100 Ibs. of seed. COTTON (DELINTED ONLY) To provide early season protection of seedlings against injury by cotton aphid, western flower thrips and tobacco thrips apply Adage 70WS at ~.6 to 6.9 oz .. per 100 Ibs. of seed. Plan't Adage treated cotton seed based on Gltes recommended by your state agricultural extension agent. In northern cotton grOV\l:1g regions such as ~C and Y.; . or where thrip pressure is expected to be severe. use Adage seed treatment followed by foliar sprays of Orthene beginning when cotton is at Ihe 1 leaf stage. Follow the Orthene product label for rates. use instructions and limitations. ' ..

SORGHOI To provide early season protection of seed I ings against injury by com leaf aphid, yellow sugar cane aphid, greenbug, chinch bug, seed com maggot, wireworm, and fire ant apply Adage 70WS at 4.6 oz. per 100 Ibs. of seed. WHEAT To provide early season protection of seedlings against injury by bird cherry-oat aphid, English grain aphid, Russian wheat aphid, greenbug, Hessian fly, and wireworm and to reduce potential spread of barley yellow dwarf virus due to the aphid wctors mentioned above. apply Adage 70WS at 0.66-1.2 oz. per 100 Ibs. of seed. Rotational Crops: Treated areas may be replanted Immediately following harvest or as soon as practical following the last application with any crop on this label or to cucurbit vegetables. fruiting v·egetables. ruberous and corm vegetables and tobacco. For all other crops, a I cO-day plantback interval must be observed . . - .. ".' . . Pesticide Storage and Disposal Store in a cool. dry place. Do not contaminate water. food, or feed by storage, disposal, or cleaning of equipment. Wastes resulting from the use' of this product may be disposed of on site or at an approv'ed waste disposal facility. If these wastes cannot be used according to label instructions, contact your State Pesticide or Env'ironmental Control Agency or the Hazardous Waste representative at the ne-arest EPA regional office for guidance in proper disposal methods. Container Disposal Triple rinse (or equiv-alent), then offer for recycling or reconditioning or puncrure and dispose of in a sanitary landfill, or by incineration, or by open burning, if allowed by state and local authorities. [fburned, keep out of smoke. For minor spills, leaks, etc .. follow all pre~autions indicated on this label and clean' up immediately. Take special care to avoid cornaminatlon of equipment and facilities during cleanup procedures and disposal of wastes. In the e\ ent of a major spIlL fire. or other emergency. call -800-888-8372, day or night. " ' , .

-----."., ... ,.,',"'" PRECAUTIONARY STATEME:'oITS Hazards to Humans and Domestic Animals CAl'TIO:'-i Hannful if swallowed. inhaled, or absorbed through skin. Avoid contact with eyes, skin. or clothing, ' A'oid breathing dust vapor, or spray mist Wash thoroughly wilh soap and water after handling. Remove contammated clothing and wash before reuse, First Aid If inhaled · , , . ' , , Ifin' eyes· If on skin or clothing If swallowed • Y10ve the persc)n to fresh air. • [fperson is not breathing. call an ambulance, then gIve aI1ifical respiration. preferably mouth to mouth, if possible, • . Call a poison,comrol center, doctor,or 1-,8QO-S8&-8372 immediately for, treatniefi advice, ' ' ,., ." • HQld eye open· and·rinse ·sloWly aoogently M'lh water for 15-20 ' minutes. • Remove contact lenses, if present, and after the first 5 minutes, then continue rinsing eye. • Call a poison control center, doctor. or 1-800-888-8372 immediately for treatment adyice, • Take off contaminated clothing. • Rinse skin immediately with plenty of water for 15-20 minutes, • Call a poison control center. doctor or 1-800-888-8372 immediately for treatment ad\lce. • Call a poison control center, doctor. or 1-800-888-8372 immediately for treatment ad'ice, • Have person SIp a glass of water if able to swallow. • Do not induce 'omiting unless told to do so by the poison control center or doctor Note to Ph~·siCian: There is no specific antidl)te if Adage 70WS is ingesied Induce emesis or la'age stomach Treat s:mptomatically, Personal Protection Equipment Applicators and other handlers must wear: • Covaalls • \" aterproof gloves • Shoes plus socks 1/11

Follow manufacturer's instructions for cleaning/maintaining PPE. Ifno such instructions exist for washables, use detergent and hot water. Keep and wash PPE separately from other laundry. Engineering Control Statements When handlers use closed systems, enclosed cabs, or aircraft in a manner that meets the requirements listed in the Worker Protection Standard (WPS) for agricultural pesticides [40 CFR l70.240(d)(4-6»). the handler PPE requirements may be reduced or modified as specified in the WPS. . . --Note: Workers must ",:€;ar IQng pants, long sleeve sllirti. an" chemical-resiStant gloves ;"hen applying Adage 70WS as a seed treatment. Surface Water .-\dvisory This product may contaminate water through drift of spray in wind. This product has a high potential for runoff for several months or more after application. Poorly draining soils and soils with shallow water tables are more prone to produce runoff that contains this product. A level. well maintained vegetative buffer strip between areas to which this product is applied and surface water features such as ponds. streams, and streams. and springs will reduce the potential for contamination of water from rainfall runoff(See manual at the following internet address: http: .. www.nrcs.usda.gO\water-quality.commollipestmgtfiles.core4.html). Runoff of this product will be reduced by 3\ aiding applications when rainfall is . forecasted .to occur within 48 hours. Ground Water Advisory Thiarnethoxam has properties and charactenstics associated with chem:cals detected in ground water. The use of this chemical in areas where soilS are penneable. particularly II here the water table is shallow may result in ground water contamination.

Environmental Hazards This pesticide is toxic to fish and aquatic invertebrates. Do not apply directly to \ater, to areas where surface water is present, or to intertidal areas below the mean high water mark. Drift or runoff from treated areas may be hazardous to aquatic organisms in neighboring areas. Do not contaminate water when disposing of equipment wash\ aters. Spray Drift Advisory Do not allow this product to drift. Adage T " trademark of Nov art is e2000 Novartis ~ovartis Crop Protection. Inc. Seed Treatment Products Greensboro. North Carolina 27419 . " . ~ .