crop-chem-docs/corpus/epa_ppls/264-1176.md

MELOCON WP

• EPA Reg No: 264-1176
• Registrant: BAYER CROPSCIENCE, LLC
• Signal word: Caution
• Active ingredients: Purpureocillium lilacinum strain 251 (40%)
• Label accepted: 2012-01-12
• Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/072444-00003-20120112.pdf

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UNlf" STATES ENVIRONMENTAL PROTECTl(" \GENCY Mr. William F. Stoneman jy^ | £ 2012 Agent for PROPHYTA Biologischer Pflanzenschutz GmbH W.F. Stoneman Company LLC P.O. Box 465 McFarland, WI 53558-0465 Re: PROPHYTA Biologischer Pflanzenschutz GmbH; MeloCon® WP EPA Registration No. 72444-3 Minor Label ("Fast Track") Amendment Submissions dated 07/19/2010, 09/13/2011, 12/12/2011, and 01/11/2012 Decision No. 437874 Dear Mr. Stoneman: The U.S. Environmental Protection Agency (EPA) reviewed your request to amend the subject product registration, which included the following changes to the product label:

1. Correction of minor formatting inconsistencies and typographical errors.
2. Modification of a phase on the front panel of the label from "For agricultural use to suppress plant parasitic nematodes in the soil" to "For control of plant-parasitic nematodes in the soil."
3. Addition of "side" to the reference statement found on the front panel of the label (i.e., "See side/back panel for additional precautionary statements").
4. Removal of specific distributor information (name and address) and addition of placeholders ("Distributed by . . ." and "Manufactured for . . .") for future distributors.
5. Modification of the Net Contents/Net Weight statement from "Net Contents" to "Net Weight" given MeloCon® WP's formulation type (i.e., wettable powder).
6. Revision of the Hazards to Humans and Domestic Animals section to align with MeloCon® WP's product-specific Toxicity Categories.
7. Modification of "chemical resistant gloves" to "waterproof gloves" in the Personal Protective Equipment section.
8. Modification of the following statement in the Personal Protective Equipment section (changes emphasized): "Mixers/loaders .and applicators must wear a dust/mist filtering respirator meeting NIOSH standards of at least N-95. R-95 or P-95."
9. Removal of reference to aircraft applications in the Engineering Controls section.
10. Removal of "cleaning equipment or" from the second statement in the Environmental Hazards section to comport with Chapter 8, Section III(A) of the Label Review Manual. CONCURRENCES SYMBOL ^ SURNAME ^ DATE ^ Iffi/P ifh.T1. il W(T""!" v * <— T* e./^ieil "l^ltf .../LJBA....V
    EPA Form 1320-1 A (1/90) rj — .3S.ii£... | In* \ i .tt^yi..« Printed on Recycled Paper OFFICIAL FILE COPY

• U.S. Government Printing Office: 2005 206-899 (mac)

William F. Stoneman EPA Registration No. 72444-3 11) Addition of a Worker Protection Standard exception (i.e., "EXCEPTION: If the product is soil incorporated or soil injected, the Worker Protection Standard, under certain circumstances, allows works to enter the treated area if there will be no contact with anything that has been treated.") and a requirement for "protective eyewear" personal protective equipment to the Agricultural Use Requirements box. 12) Modification of "chemical resistant gloves" to "waterproof gloves" in the Agricultural Use Requirements box. 13) Clarification and enhancement of the Directions for Use section, including the following notable changes: a) addition of certain nematode pests (e.g., awl nematodes (Dolichodorus species) and citrus nematode (Tylenchulus semipenetrans))', b) addition of specific instructions for tank mixing; c) modification of crop names to align with information presented in 40 C.F.R. § 180.41; d) addition of certain crop groups and commodities (e.g., artichoke, herbs and spices, berries, pome fruits, and avocado); e) revision of specific instructions that outline application types, timing, methods, rates, and frequency; and f) revision of the chemigation instructions (e.g., inclusion of micro-irrigation). 14) Modification of the Container Handling section per Pesticide Registration Notice 2007-4 and Chapter 13 of the Label Review Manual. All the changes referred to above, submitted in connection with registration under section 3(c)(5) of the Federal Insecticide, Fungicide, and Rodenticide Act, are acceptable provided that you submit two (2) copies of your final printed labeling before you release the product for shipment. Refer to the A-79 enclosure for a further description of final printed labeling. Your release for shipment of the product bearing the amended labeling constitutes acceptance of these conditions. If you have any questions regarding this letter, please contact Ms. Jeannine Kausch by telephone (703-347.-8920) or email (kausch.jeannine@epa.gov). . A stamped copy of the label is enclosed for your records. Sincerely, Sheryl K. Reilly, Ph.D.>Oiief Microbial Pesticides Branch Biopesticides and Pollution Prevention Division (751 IP) Enclosures: (1) MeloCon® WP Accepted Label (2) A-79 Enclosure

r r V^ M ACCEPTED JAN 1 2 2012 U*ter the Federal Insecticide, fungicide, Rodenttekte Art, as amended, for Alternate Brand Names: BioAct® WP and NemOut™WP Biological Nematicide For control of plant-parasitic nematodes in the soil Active Ingredient: Paecilomyces lilacinus strain 25 1 * ................................................. 40.0% Other Ingredients : .......................................................................................... 60.0% Total: .................................................................................... ...................... 100.0%

• Contains a minimum of 1 x 1011 viable spores/gram KEEP OUT OF REACH OF CHILDREN CAUTION registered under FIRST AID If swallowed: If on skin or clothing: If inhaled: If in eyes: • Call a poison control center or doctor immediately for treatment advice. • Have person sip a glass of water if able to swallow. • Do not induce vomiting unless told to do so by a poison control center or doctor. • Do not give anything by mouth to an unconscious person. • Take off contaminated clothing. • Rinse skin immediately with plenty of water for 1 5-20 minutes. • Call a poison control center or doctor for treatment advice. • Move person to fresh air. • If person is not breathing, call 911 or an ambulance, then give artificial respiration, preferably mouth-to-mouth if possible. • Call a poison control center or doctor for further treatment advice. • Hold eye open and rinse slowly and gently with water for 15-20 minutes. Remove contact lenses, if present, after the first 5 minutes, then continue rinsing. • Call a poison control center or doctor for treatment advice. Hot Line Number Have the product container or label with you when calling a poison control center or doctor, or going for treatment. For emergency information, call a local poison control center at 1-800-222-1222. If appropriate: See side/back panel for additional precautionary statements EPA Reg. No. 72444-3 • EPA Est. No. 72444-DEU-001 Manufactured by: PROPHYTA Biologischer Pflanzenschutz GmbH Inselstrasse 12 D-23999 Malchow/Poel, Germany Net Weight: Distributed by: Name and Address of respective distributor Page lof 12

f (PRECAUTIONARY STATEMENTS HAZARDS TO HUMANS AND DOMESTIC ANIMALS: CAUTION. Harmful if swallowed, absorbed through skin or inhaled. Causes moderate eye irritation. Avoid contact with skin, eyes or clothing. Avoid breathing dust or spray mist. Wear protective eyewear. Wash thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco or using the toilet. Remove and wash contaminated clothing before reuse. PERSONAL PROTECTIVE EQUIPMENT (PPE): Applicators and other handlers must wear: • Long-sleeved shirt and long pants • Waterproof gloves • Shoes plus socks • Protective eyewear Mixers/loaders and applicators must wear a dust/mist filtering respirator meeting NIOSH standards of at least N-95, R-95 or P- 95. Repeated exposure to high concentrations of microbial proteins can cause allergic sensitization. Follow manufacturer's instructions for cleaning/maintaining PPE. If no such instructions for washables, use detergent and hot water. Keep and wash PPE separately from other laundry. ENGINEERING CONTROLS: When handlers use closed systems or enclosed cabs in a manner that meets the requirements listed in the Worker Protection Standard (WPS) for agricultural pesticides [40 CFR 170.240(d)(4-5)], the handler PPE requirements may be reduced or modified as specified in the WPS. IMPORTANT: When reduced PPE is worn because a closed system is being used, handlers must be provided all PPE specified above for "applicators and other handlers" and have such PPE immediately available for use in an emergency, such as a spill or equipment breakdown. USER SAFETY RECOMMENDATIONS Users should: • Remove clothing/PPE immediately if pesticide gets inside. Then wash thoroughly and put on clean clothing. • Remove PPE immediately after handling this product. Wash the outside of gloves before removing, soon as possible, wash thoroughly and change into clean clothing. As ENVIRONMENTAL HAZARDS: For terrestrial uses: Do not apply directly to water, or to areas where surface water is present or to intertidal areas below the mean high water mark. Do not contaminate water when disposing of equipment wash waters or rinsate. Page 2 of 12

( DIRECTIONS FOR USE It is a violation of Federal law to use this product in a manner inconsistent with its labeling. Do not apply this product in a way that will contact workers or other persons, either directly or through drift. Only protected handlers may be in the area during application. For any requirements specific to your State or Tribe, consult the State or Tribal agency responsible for pesticide regulation. Read the entire label before using. AGRICULTURAL USE REQUIREMENTS Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR Part 170. This Standard contains requirements for the protection of agricultural workers on farms, forests, nurseries and greenhouses, and handlers of agricultural pesticides. It contains requirements for training, decontamination, notification and emergency assistance. It also contains specific instructions and exceptions pertaining to the statements on this label about personal protective equipment (PPE) and restricted-entry interval. The requirements in this box only apply to uses of this product that are covered by the Worker Protection Standard. Do not enter or allow worker entry into treated areas during the restricted-entry interval (REI) of 4 hours. EXCEPTION: If the product is soil incorporated or soil injected, the Worker Protection Standard, under certain circumstances, allows workers to enter the treated area if there will be no contact with anything that has been treated. PPE required for early entry to treated areas (that is permitted under the Worker Protection Standard and that involves contact with anything that has been treated, such as plants, soil, or water) is: • Coveralls • Waterproof gloves • Shoes plus socks • Protective eyewear NON-AGRICULTURAL USE REQUIREMENTS The requirements in this box apply to uses of this product that are NOT within the scope of the Worker Protection Standard (WPS) for agricultural pesticides (40 CFR Part 170). The WPS applies when this product is used to produce agricultural plants on farms, forests, nurseries or greenhouses. Keep unprotected persons out of treated areas until sprays have dried. PRODUCT INFORMATION: MeloCon* WP is a water dispersible powder containing spores of a soil fungus that parasitizes many species of plant-parasitic nematodes. MeloCon® WP is intended for use as part of an Integrated Pest Management (IPM) system. When used as part of a complete pest management program, MeloCon WP reduces crop damage by plant-parasitic nematodes. FOR CONTROL OF CROP DAMAGE CAUSED BY THE FOLLOWING PESTS: Awl nematodes (Dolichodons species) Burrowing nematode (Radopholus similis) Citrus nematode (Tylenchulus semipenetrans) Cyst nematodes (Heterodera and Globodera species) False root-knot nematodes (Naccobus species) Lance nematodes (Hoplolaimus species) Lesion nematodes (Pratylenchus species) Needle nematodes (Longidorus and Paralongidorus species) Reniform nematode (Rotylenchulus reniformis) Ring nematodes (Criconemoides, Criconemella and Mesocriconema species) Root-knot nematodes (Meloidogyne species) Spiral nematodes (Helicotylenchus and Rotylenchus species) Stem nematode (Ditylenchus dipsaci) Sting nematode (Belonolaimus longicaudatus) Stubby root nematodes (Trichodorus and Paratrichodorus species) Stunt nematodes (Tylenchorhynchus species) Page 3 of 12

MIXING DIRECTIONS: • Determine the total volume of water needed for application according to the application tables below. • Fill the spray tank to approximately % (three-fourths) of the desired volume with clean water and begin agitation. • Add the specified amount of MeloCon® WP to the tank (consult application tables below). Do not allow spray mixture to stand overnight or for prolonged periods. Finish filling the tank to the desired volume that provides maximum coverage. • Maintain agitation throughout the mixing and application process. • Do not use screens finer than 50 mesh in sprayers or other pressurized application systems. • For best results, prepare the mixture immediately before use. Tank Mixing: • Application efficiency may be enhanced by inclusion of a soil wetting agent to help the spores penetrate soil into the root zone. • Do NOT mix MeloCon® WP with chlorothalonil, mancozeb, triazole or strobilurin fungicides. • Do not mix with strong acids, bases, or other caustic materials. Maintain a neutral or slightly acidic pH (6-7) in the spray tank. • Mix MeloCon® WP only with products for which such mixing is permitted by the label for that product. Test the physical compatibility of unfamiliar mixtures by combining small amounts of the products in the intended proportions and mix order before actual use ("jar test"). Observe the most restrictive of the labeling limitations and precautions of all products used in mixtures. • For information on which adjuvants and pesticides can be mixed with MeloCon® WP without harming the beneficial fungus it contains, contact your Technical Sales Representative or the Manufacturer. • For preparation of a tank mix, add the other products first. If the other products are likely to cause foaming, however, add them after filling up the tank to the desired volume of water. Then add MeloCon* WP. Page 4 of 12

(Use Directions Crop group, crop or use site Application type/timing Application rates and instructions Fruiting vegetables, including Tomato, Tomatillo, Peppers (all types) and Eggplant Leafy vegetables, including Arugula, Head and Leaf Lettuce, Spinach (all types), Celery (all types), Corn salad (Mache), Cress (all types), Endive, Radicchio and Rhubarb Brassica (cole) leafy vegetables, including Broccoli (all types), Brussels Sprouts, Cabbage (all types), Cauliflower, Collards, Kale and Mustard Greens (all types) Cucurbit vegetables, including Watermelon, Cantaloupe, Muskmelon (including Honeydew Melon and other melons), Cucumbers (including pickling), Edible Gourds, Pumpkins and Squash (all types) Strawberry, Artichoke, Pineapple Tobacco, Herb & spice crops Indoor- or outdoor-grown cut flowers and ornamental bulbs Application to field soils before planting or transplanting Apply 0.2 to 0.4 pound of MeloCon* WP per acre. Application can be made by the following methods: • Drenching, drip (trickle) or sprinkler application (see "Instructions for MeloCon* WP Application through Irrigation Systems"). To enhance penetration of spores into the root zone, consider mixing MeloCon* WP with a soil wetting agent. • Surface spray on moist soil with 40-100 gallons water per acre followed by incorporation using light tillage. • Surface spray with 20 - 40 gallons water per acre followed by overhead irrigation. Use enough irrigation water to wet the soil into the root zone. • Direct injection to anticipated root depth using shank or other soil injection equipment. Apply with 30 - 40 gallons water per acre. Pre-plant application may be either broadcast over an entire field or concentrated (banded) into planting rows. Apply when soil temperature at 4-inch depth is 60°F or higher. Bioactivity of MeloCon* WP is greatest at soil temperatures between 70° and 90°F. Apply to nematode-infested (non-fumigated) soil up to 14 days before planting or transplanting. Follow up with applications on the field soil at or after planting or transplanting (see third section below). If the soil has been fumigated recently (within 2 weeks), make the initial MeloCon* WP application to transplants just before transplanting into the field, as described in the section that follows. Alternatively, apply MeloCon* WP to fumigated soil at or after planting or transplanting (see third section below). Application to transplants just before transplanting into the field Mix 0.8 ounce (% cup) of MeloConWP with 5 gallons of water, and apply as a drench spray to 100 cubic feet of soil or other growth media in transplant flats, pots or other rooting containers. Follow the application with sufficient additional water (such as by drenching or overhead irrigation) to saturate the soil or rooting medium. As needed, follow up with applications at 4- to 6 -week intervals at or after transplanting, as described in the section that follows. Application to field soils at or after planting or transplanting Apply 0.2 to 0.4 pound of MeloConWP per acre by one of the following methods: • Drip (trickle) application (see "Instructions for MeloCon* WP Application through Irrigation Systems"). • Banded spray 4" to 6" wide, in-furrow at planting (over or under the seed line). Apply sufficient water during or immediately after applications to thoroughly wet the soil into the root zone. MeloCon* WP can also be mixed with water and injected directly into the rooting zone using a shank or other injection equipment, preferably on both sides of the plant row. Repeat applications at 4- to 6-week intervals as needed to control plant-parasitic nematode populations during the crop period. To enhance penetration of spores into the root zone, consider mixing MeloCon* WP with a soil wetting agent Page 5 of 12

Crop group, crop or use site Application type/timing Application rates and instructions Root and tuber vegetables, including Beets (except Sugar Beet), Carrot, Cassava, Ginger, Horseradish, Parsnips, Radish, Rutabaga, Taro, Yams and Turnip Onions, Garlic and other Bulb vegetables Application to field soils before planting or transplanting Apply 0.2 to 0.4 pound of MeloConWP per acre. Applications can be made by the following methods: • Drenching, drip (trickle) or sprinkler application (see "Instructions for MeloCon WP Application through Irrigation Systems"). To enhance penetration of spores into the root zone, consider mixing MeloCon® WP with a soil wetting agent. • Surface spray on moist soil with 40 - 100 gallons water per acre followed by incorporation using light tillage. • Surface spray with 20 - 40 gallons water per acre followed by overhead irrigation. Use enough irrigation water to wet the soil into the root zone. • Direct injection to anticipated root depth using shank or other soil injection equipment. Apply with 30 - 40 gallons water per acre. Pre-plant applications may be either broadcast over an entire field or concentrated (banded) into planting rows. Apply when soil temperature at 4-inch depth is 60°F or higher. Bioactivity of MeloCon* WP is greatest at soil temperatures between 70° and 90°F. Apply to nematode-infested (non-fumigated) soil up to 14 days before planting or transplanting. Follow up with applications on the field soil at planting or transplanting (see third section below). If the soil has been fumigated recently (within 2 weeks), make the initial MeloCon® WP application to transplants just before transplanting into the field, as described in the section that follows. Alternatively, apply MeloCon* WP to fumigated soil at planting or transplanting (see third section below). Application to transplants just before transplanting into the field Mix 0.8 ounce ('/< cup) of MeloCon* WP with 5 gallons of water, and apply as a drench spray to 100 cubic feet of soil or other growth media in transplant flats, pots or other rooting containers. Follow the application with sufficient additional water (such as by drenching or overhead irrigation) to saturate the soil or rooting medium. Application to field soils at planting or transplanting Apply 0.2 to 0.4 pound of MeloConWP per acre by one of the following methods: • Drip (trickle) application (see "Instructions for MeloCon WP Application through Irrigation Systems"). • Banded spray 4" to 6" wide, in-fiirrow at planting (over or under the seed row). Apply sufficient water during or immediately after applications to thoroughly wet the soil into the root zone. MeloCon® WP can also be mixed with water and injected directly into the rooting zone using a shank or other injection equipment, preferably on both sides of the plant row. To enhance penetration of spores into the root zone, consider mixing MeloCon* WP with a soil wetting agent. Page 6 of 12

( Crop group, crop or use site Application type/timing Application rates and instructions Grapevines (Wine Grapes, Table Grapes and Raisins) Berries, including Blackberries, Blueberries, Cranberry, Currants, Elderberry, Gooseberry, Huckleberry, Loganberry, Lingonberry and Raspberries Citrus fruits Pome fruits, including Apple, Loquat, Pear and Quince Stone fruits, including Apricot, Cherries, Nectarine, Peach, Plums and Plumcot Tree nuts, including Almond, Beech Nut, Cashew, Chestnut, Hazelnut, Macadamia Nut, Pecan and Walnut Avocado, Coffee, Pistachio, Pomegranate For multiple trees or vines (full or partial orchard or vineyard application) Apply 0.2 to 0.4 pound of MeloCon8 WP per acre by one of the following methods: • Drip (trickle) application (see "Instructions for MeloCon® WP Application through Irrigation Systems"). • Micro-irrigation application (see "Instructions for MeloCon* WP Application through Irrigation Systems"). Apply through micro-irrigation only when the irrigation is soil directed, the heights of the nozzles are below the canopy and irrigation water does not come into contact with aboveground harvestable food commodities. DO NOT use mist sprayers, which produce small droplets likely to drift. • Injection with 30 - 40 gallons water per acre directly into the root zone using a shank or other injection equipment. • Soil-directed spray with 30-100 gallons per acre from stem to drip line (outer reaches of the branches or vines), ensuring foliage and aboveground harvestable food commodities are not contacted by the spray. Apply sufficient water during or immediately after application to thoroughly wet the soil into the root zone. Alternatively, applications can be made before or during rainfall to assist in movement to the roots. To enhance penetration of spores into the root zone, consider mixing MeloCon* WP with a soil wetting agent. Repeat applications every 2-4 months or during root flush, as needed. For individual trees or vines Mix 0.5 ounce (3 tablespoons) of MeIoConWP in 5 gallons of water, and apply as a drench spray to the soil from stem to drip line (outer reaches of the branches or vines), ensuring foliage and aboveground harvestable food commodities are not contacted by the spray. Five gallons of mix will treat up to 500 square feet of soil, or the area under approximately 5 mature trees or vines. Apply sufficient water during or immediately after application to thoroughly wet the soil into the root zone. Alternatively, applications can be made before or during rainfall to assist in movement to the roots. To enhance penetration of spores into the root zone, consider mixing MeloCon WP with a soil wetting agent. Repeat applications every 2-4 months or during root flush, as needed. Banana and Plantain At planting For 250 plants: Mix 1.6 ounces (V, cup) of MeloCon* WP in water (20 - 100 gallons per acre), and apply as a drench or coarse spray in the planting hole just before placing the plant in the hole and then around the base of each plant immediately after planting. Use conventional ground application equipment, backpack sprayers or hand-held dippers for these soil-directed applications. Water in with standard (quantity and equipment) irrigation to wet the soil into the root zone, or apply before rainfall. To enhance penetration of spores into the root zone, consider mixing MeloCon® WP with a soil wetting agent. Established plants, every 4 months For 250 plants: Mix 1.6 ounces ('/, cup) of MeloCon* WP in water (20 - 100 gallons per acre). Apply suspension in a 6-inch radius to the soil around daughter suckers using conventional ground application equipment or backpack sprayers. Alternatively, apply through micro-irrigation (see "Instructions for MeloCon* WP Application through Irrigation Systems"). Apply through micro-irrigation only when the irrigation is soil directed, the heights of the nozzles are below the canopy and irrigation water does not come into contact with aboveground harvestable food commodities. DO NOT use mist sprayers, which produce small droplets likely to drift. Water in with standard (quantity and equipment) irrigation to wet the soil into the root zone, or apply before rainfall. To enhance penetration of spores into the root zone, consider mixing MeloCon® WP with a soil wetting agent. Paee7ofl2

Crop group, crop or use site Application type/timing Application rates and instructions Sugar beet ^ffiyO.6—Q9pcundcflvffcGtrfc WP in a minimum of 20 gallons of water per acre into the seed furrow and cover with soil. plating Peanut (Choose the most appropriate treatment method to fit your operation and management!) irtxipcralicn pricr to bed fearing —Q6pcxnicfrvHcCirf WP in a minimum of 20 gallons of water per acre to moist soil (if soil is not moist, apply prior to rainfall or pre-plant irrigation) prior to bed forming. Follow up with a pre-pegging application as described below. Pre-planting bed treatment In-furrow application At minimum tillage: Post-plant irrigation or rainfall drench Post- planting (pre-pegging) drench Apply 0.3 - 0.6 pound of MeloCon® WP in a minimum of 20 gallons of water per acre in a 6- to 8-inch band on top of the row (on double row peanuts, in a 14- to 16-inch band) and incorporate thoroughly into the top 6 to 8 inches of moist soil (if soil is not moist, apply prior to rainfall or pre-plant irrigation). Follow up with a pre-pegging application as described below. Apply 0.3 - 0.6 pound of MeloCon* WP in a minimum of 20 gallons of water per acre into the seed furrow and cover with soil. If possible, apply prior to an at-planting irrigation. To enhance penetration of spores into the root zone, consider mixing MeloCon* WP with a soil wetting agent. MeloCon* WP may be applied in conjunction with liquid peanut inoculants. Follow up with a pre-pegging application as described below. Apply 0.3 - 0.6 pound of MeloCon* WP in a minimum of 20 gallons of water per acre to moist soil. Water in the product immediately after planting. To enhance penetration of spores into the root zone, consider mixing MeloCon* WP with a soil wetting agent. Follow up with a pre-pegging application as described below. Apply 0.3 - 0.6 pound of MeloCon* WP in a minimum of 20 gallons of water per acre. Spray prior to rainfall or irrigation, prior to pegging, and at the base of the plants. The application is only to be soil directed. To enhance penetration of spores into the root zone, consider mixing MeloCon* WP with a soil wetting agent. Page 8 of 12

Crop group, crop or use site Application type/timing ! Application rates and instructions u Cotton (Choose the most appropriate treatment method to fit your operation and management!) Pre-plant incorporation prior to bed forming Apply 0.15 - 0.3 pound of MeloCon® WP in a minimum of 20 gallons of water per acre to moist (if soil is not moist, apply prior to rainfall or pre-plant irrigation) soil prior to bed forming. Follow up with a post-emergent drench as described below. In-furrow treatment Apply 0.15 - 0.3 pound of MeloCon® WP in a minimum of 20 gallons of water per acre into the furrow prior to planting cotton. Apply into the seed furrow and cover with soil. If possible, apply prior to an at-planting irrigation. To enhance penetration of spores into the root zone, consider mixing MeloCon* WP with a soil wetting agent. Follow up with a post-emergent drench as described below. At minimum tillage: Post-plant irrigation or rainfall drench Apply 0.15-0.3 pound of MeloCon® WP in a minimum of 20 gallons of water per acre to moist soil and water in the product immediately after planting. To enhance penetration of spores into the root zone, consider mixing MeloCon® WP with a soil wetting agent. Follow up with a post-emergent drench as described below. Post-emergence application at the 6th to 7* true leaf stage Apply 0.15 - 0.3 pound of MeloCon® WP in 30 - 40 gallons of water per acre to cotton using shank or other soil injection equipment. Apply when cotton is in the 6th to 7m true leaf stage of growth by placing into the soil alongside the seed furrow. Application equipment can have either one or two coulters and knives per row. To enhance penetration of spores into the root zone, consider mixing MeloCon* WP with a soil wetting agent. This treatment will extend the suppression of nematode populations when applied during the growing season and after the pre-plant application of a soil fumigant, at- plant application of a contact nematicide or use of a seed treatment nematicide. Potato / Sweet potato (Choose the most appropriate treatment method to fit your operation and management!) Pre-planting application Apply 0.6 - 0.9 pound of MeloCon* WP per acre to potatoes / sweet potatoes planted in 42- to 48-inch rows. Apply in a 14-inch banded or broadcast spray of 20 - 40 gallons water per acre while forming the rows / planting hills and incorporate thoroughly into the top 4-10 inches of moist soil. Can be applied up to 21 days prior to potato / sweet potato transplant. Drench at transplanting Apply 0.6 - 0.9 pound of MeloCon® WP per acre. Disperse product entirely in a supply tank and add it to transplant water. Apply with at least 30 gallons transplant water per acre. To enhance penetration of spores into the root zone, consider mixing MeloCon* WP with a soil wetting agent. Turf Established turf, every 2 months Apply 0.7 ounce (4 tablespoons) of MeloCon® WP in minimum of 5 gallons of water on 1,000 square feet of turf using conventional ground application equipment; follow immediately (while leaves are still wet from application) by overhead irrigation, drenching the product into the root zone with at least 0.5 inches of water. Alternatively, apply the product through an overhead irrigation system. If irrigation is not available, apply the product suspension prior to or during rainfall. To enhance penetration of spores into the root zone, consider mixing MeloCon* WP with a soil wetting agent. Page 9 of 12

INSTRUCTIONS FOR MeloCon® WP APPLICATION THROUGH IRRIGATION SYSTEMS Applications through Drip (Trickle) or Sprinkler Irrigation: Apply MeloCon® WP only through sprinkler, including center pivot, lateral move, end tow, side (wheel) roll, traveler, big gun, solid set, or handmove, and drip (trickle), including micro-irrigation, systems and either before planting or to the planted crop/use site at the appropriate rates indicated in the previous table. If applied in this manner, irrigate with enough water to saturate the soil to the depth of the root zone. Addition of an approved soil wetting agent at the manufacturer's recommended mix rate may enhance penetration of spores to the rooting zone. For information on which adjuvants and pesticides can be mixed with MeloCon® WP without harming the beneficial fungus it contains, contact your Technical Sales Representative or the Manufacturer. Do not apply MeloCon® WP through any irrigation systems other than those specified above. Crop injury or lack of effectiveness can result from non-uniform distribution of treated water. If you have questions about calibration of your irrigation systems, you should contact State Extension Service specialists, equipment manufacturers or other experts. Do not connect an irrigation system (including greenhouse systems) used for pesticide application to a public water system unless the pesticide label-prescribed safety devices for public water systems are in place. A person knowledgeable of the pesticide application system and responsible for its operation, or under the supervision of the responsible person, shall shut the system down and make necessary adjustments should the need arise. Pesticide Application Using Public Water Systems:

1. Public water system means a system for the provision to the public of piped water for human consumption if such system has at least 15 service connections or regularly serves an average of at least 25 individuals daily at least 60 days out of the year.

2. Pesticide application systems connected to public water systems must contain a functional, reduced-pressure zone, back flow preventer (RPZ) or the functional equivalent in the water supply line upstream from the point of pesticide introduction. As an option to the RPZ, the water from the public water system should be discharged into a reservoir tank prior to pesticide introduction. There shall be a complete physical break (air gap) between the flow outlet end of the fill pipe and the top or overflow rim of the reservoir tank of at least twice the inside diameter of the fill pipe.

3. The pesticide injection pipeline must contain a functional, automatic, quick-closing check valve to prevent the flow of fluid back toward the injection pump.

4. The pesticide injection pipeline must contain a functional, normally closed, solenoid-operated valve located on the intake side of the injection pump and connected to the system interlock to prevent fluid from being withdrawn from the supply tank when the irrigation system is either automatically or manually shut down.

5. The system must contain functional interlocking controls to automatically shut off the pesticide injection pump when the water pump motor stops, or in cases where there is no water pump, when the water pressure decreases to the point where pesticide distribution is adversely affected.

6. Systems must use a metering pump, such as a positive displacement injection pump (e.g., diaphragm pump) effectively designed and constructed of materials that are compatible with pesticides and capable of being fitted with a system interlock.

7. Do not apply when wind speed favors drift beyond the area intended for treatment.

8. Apply the entire treatment during the first 1/3 of the total irrigation.

9. Mix MeloCon® WP in the supply tank to a concentration appropriate to cover the area to be treated.

10. Agitation is required for mixing and maintaining the suspension of the spores of the active agent in the injection solution. Apply all MeloCon® WP within 24 hours after mixing with water. Pesticide Application Using Drip (Trickle) Irrigation:

11. The system must contain a functional check valve, vacuum relief valve, and low pressure drain appropriately located on the irrigation pipeline to prevent water source contamination from back flow.

12. The pesticide injection pipeline must contain a functional, automatic, quick-closing check valve to prevent the flow of fluid back toward the injection pump.

13. The pesticide injection pipeline must also contain a functional, normally closed, solenoid-operated valve located on the intake side of the injection pump and connected to the system interlock to prevent fluid from being withdrawn from the supply tank when the irrigation system is either automatically or manually shut down.

14. The system must contain functional interlocking controls to automatically shut off the pesticide injection pump when the water pump motor stops.

15. The irrigation line or water pump must include a functional pressure switch, which will stop the water pump motor when the water pressure decreases to the point where pesticide distribution is adversely affected. Page 10 of 12

16. Systems must use a metering pump, such as a positive displacement injection pump (e.g., diaphragm pump) effectively designed and constructed of materials that are compatible with pesticides and capable of being fitted with a system interlock.

17. Apply the entire treatment during the first 1/3 of the total irrigation.

18. Mix MeloCon® WP in the supply tank to a concentration appropriate to cover the area to be treated.

19. Agitation is required for mixing and maintaining the suspension of the spores of the active agent in the injection solution. Apply all MeloCon® WP within 24 hours after mixing with water. Pesticide Application Using Sprinkler Irrigation:

20. The system must contain a functional check valve, vacuum relief valve, and low pressure drain appropriately located on the irrigation pipeline to prevent water source contamination from back flow.

21. The pesticide injection pipeline must contain a functional, automatic, quick-closing check valve to prevent the flow of fluid back toward the injection pump.

22. The pesticide injection pipeline must also contain a functional, normally closed, solenoid-operated valve located on the intake side of the injection pump and connected to the system interlock to prevent fluid from being withdrawn from the supply tank when the irrigation system is either automatically or manually shut down.

23. The system must contain functional interlocking controls to automatically shut off the pesticide injection pump when the water pump motor stops.

24. The irrigation line or water pump must include a functional pressure switch, which will stop the water pump motor when the water pressure decreases to the point where pesticide distribution is adversely affected.

25. Systems must use a metering pump, such as a positive displacement injection pump (e.g., diaphragm pump) effectively designed and constructed of materials that are compatible with pesticides and capable of being fitted with a system interlock.

26. Do not apply when wind speed favors drift beyond the area intended for treatment.

27. Apply the entire treatment during the first 1/3 of the total irrigation.

28. Mix MeloCon® WP in the supply tank to a concentration appropriate to cover the area to be treated.

29. Agitation is required for mixing and maintaining the suspension of the spores of the active agent in the injection solution. Apply all MeloCon® WP within 24 hours after mixing with water. Pesticide Application Using Micro-irrigation:

30. The system must contain a functional check valve, vacuum relief valve, and low pressure drain appropriately located on the irrigation pipeline to prevent water source contamination from back flow.

31. The pesticide injection pipeline must contain a functional, automatic, quick-closing check valve to prevent the flow of fluid back toward the injection pump.

32. The pesticide injection pipeline must also contain a functional, normally closed, solenoid-operated valve located on the intake side of the injection pump and connected to the system interlock to prevent fluid from being withdrawn from the supply tank when the irrigation system is either automatically or manually shut down.

33. The system must contain functional interlocking controls to automatically shut off the pesticide injection pump when the water pump motor stops.

34. The irrigation line or water pump must include a functional pressure switch, which will stop the water pump motor when the water pressure decreases to the point where pesticide distribution is adversely affected.

35. Systems must use a metering pump, such as a positive displacement injection pump (e.g., diaphragm pump) effectively designed and constructed of materials that are compatible with pesticides and capable of being fitted with a system interlock.

36. Apply only when the irrigation is soil directed, the heights of the nozzles are below the canopy and irrigation water does not come into contact with aboveground harvestable food commodities.

37. Apply the entire treatment during the first 1/3 of the total irrigation.

38. Mix MeloCon® WP in the supply tank to a concentration appropriate to cover the area to be treated.

39. Agitation is required for mixing and maintaining the suspension of the spores of the active agent in the injection solution. Apply all MeloCon® WP within 24 hours after mixing with water. Page 11 of 12

STORAGE AND DISPOSAL Do not contaminate water, food or feed by storage and disposal. PESTICIDE STORAGE Store in a cool, dry place (at 35 - 40°F or below), out of direct sunlight, and away from heat sources for up to 6 months. Product is stable for up to 12 months when stored frozen. Keep from overheating. PESTICIDE DISPOSAL To avoid wastes, use all material in this container by application according to label directions. If wastes cannot be avoided, offer remaining product to a waste disposal facility or pesticide disposal program (often such programs are run by state or local governments or by industry). CONTAINER HANDLING Nonrefillable container. Do not reuse or refill this container. Completely empty bag into application equipment. Then offer for recycling if available or dispose of empty bag in a sanitary landfill or by incineration. Do not burn, unless allowed by state and local ordinances. If burned, stay out of smoke. If outer box is contaminated, dispose of it in the same manner as required for the bag. Manufactured for (name of respective distributor) by PROPHYTA Biologischer Pflanzenschutz GmbH, Inselstrasse 12, D-23999 Malchow/Poel, GERMANY WARRANTY - PROPHYTA Biologischer Pflanzenschutz GmbH warrants that this product conforms to the description on this label and is reasonably fit for the purposes set forth on this label, when used according to directions under normal use conditions. Neither this warranty nor any other warranty of merchantability or fitness for a particular purpose, expressed or implied, extends to the use of this product contrary to the label instructions; the buyer assumes the risk of any such uses. Batch N°: Phyla Tel.: +49 (O) 3S425 -23-0 Insslstrasse 12 G.ST Fa..: +49 (O) 3S425 - 23 23 D-23999 Malcboiv / Poel E-Mail: info@propbyta.com Germany Pace 12 of 12