40 KiB
CRUISER VIBRANCE QUATTRO
- EPA Reg No: 100-1527
- Registrant: SYNGENTA CROP PROTECTION, LLC
- Signal word: Caution
- Active ingredients: Thiamethoxam (5.75%); Fludioxonil (0.72%); Metalaxyl-M (0.86%); Difenoconazole (3.45%); Sedaxane (1.44%)
- Label accepted: 2026-06-23
- Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000100-01527-20260623.pdf
June 23, 2026 Patsy Laird Regulatory Manager, Seedcare Syngenta Crop Protection, LLC P.O. Box 18300 Greensboro, NC 27419 Subject: Label Amendment - Registration Review Mitigation for Sedaxane Product Name: Cruiser® Vibrance® Quattro EPA Registration Number: 100-1527 Application Date: February 13, 2026 Case Number: 684988 Dear Mrs. Patsy Laird: The Agency, in accordance with the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), as amended, has completed reviewing all the information submitted with your application to support the Registration Review of the above referenced product in connection with the Sedaxane Interim Decision, and has concluded that your submission is acceptable. The label referred to above, submitted in connection with registration under FIFRA, as amended, is acceptable. Should you wish to add/retain a reference to the company’s website on your label, then please be aware that the website becomes labeling under the Federal Insecticide, Fungicide, and Rodenticide Act and is subject to review by the Agency. If the website is false or misleading, the product would be misbranded and unlawful to sell or distribute under FIFRA section 12(a)(1)(E). 40 CFR 156.10(a)(5) list examples of statements EPA may consider false or misleading. In addition, regardless of whether a website is referenced on your product’s label, claims made on the website may not substantially differ from those claims approved through the registration process. Therefore, should the Agency find or if it is brought to our attention that a website contains false or misleading statements or claims substantially differing from the EPA approved registration, the website will be referred to the EPA’s Office of Enforcement and Compliance Assurance.
Page 2 of 2 EPA Reg. No. 100-1527 Decision No. 684988 A stamped copy of your labeling is enclosed for your records. This labeling supersedes all previously accepted labeling and must be used at your next label printing. You must submit one copy of the final printed labeling before you release the product for shipment with the new labeling. In accordance with 40 CFR 152.130(c), you may distribute or sell this product under the previously approved labeling for 12 months from the date of this letter. After 12 months, you may only distribute or sell this product if it bears this new revised labeling or subsequently approved labeling. “To distribute or sell” is defined under FIFRA section 2(gg) and its implementing regulation at 40 CFR 152.3. If you have any questions about this letter, please contact Samantha Carter by phone at 202-566-1179, or via email at [email protected]. Sincerely, Marianne Walters, Team Lead Risk Management and Implementation Branch 3 Pesticide Re-Evaluation Division Office of Pesticide Programs ENCLOSURE: Stamped label
(Master Label) THIAMETHOXAM GROUP4A INSECTICIDE DIFENOCONAZOLE GROUP3 FUNGICIDE MEFENOXAM GROUP4 FUNGICIDE SEDAXANE GROUP 7 FUNGICIDE FLUDIOXONIL GROUP12 FUNGICIDE Cruiser®Vibrance®Quattro A seed treatment product for protection against damage from certain insects and diseases of small grain cereals. Active Ingredient: Thiamethoxam1. ...................................................................................................... 5.75% Difenoconazole2: ..................................................................................................... 3.45% Mefenoxam3: ........................................................................................................... 0.86% Fludioxonil4: ............................................................................................................. 0.72% Sedaxane5............................................................................................................... 1.44% Other Ingredients: 87.78% Total: 100.00% 1CAS No. 153719-23-4 2CAS No. 119446-68-3 3CAS Nos. 70630-17-0 and 69516-34-3 4CAS No. 131341-86-1 5CAS No. 874967-67-6 Cruiser Vibrance Quattro contains 0.51 lb. thiamethoxam, 0.31 lb. difenoconazole, 0.08 lb. mefenoxam, 0.06 lb. fludioxoniln and 0.13 lb. sedaxane per gallon. KEEP OUT OF REACH OF CHILDREN. CAUTION See additional precautionary statements and directions for use in booklet [on label]. EPA Reg. No. 100-1527 EPA Est. No. XXXXX Net Contents 6/23/2026 100-1527
-2- FIRST AID Have the product container with you when calling a poison control center or doctor, or going for treatment. HOTLINE NUMBER For 24-Hour Medical Emergency Assistance (Human or Animal) or Chemical Emergency Assistance (Spill, Leak, Fire, or Accident), Call 1-800-888-8372 PRECAUTIONARY STATEMENTS Personal Protective Equipment (PPE)
Mixers, loaders, applicators and other handlers must wear: Long-sleeved shirt and long pants Shoes plus socks Chemical-resistant gloves made of polyvinyl chloride (PVC) , nitrile rubber , butyl rubber , barrier laminate, neoprene rubber , natural rubber , polyethylene, or Viton™
Follow manufacturer’s instructions for cleaning/maintaining PPE. If no such instructions for washables exist, use detergent and hot water. Keep and wash PPE separately from other laundry.
Engineering Control Statements
When handlers use closed systems in a manner that meets the requirements listed in the Worker Protection Standard (WPS) for agricultural pesticides (40 CFR 170.607 (d) and (e)), the handler PPE requirements may be reduced or modified as specified in the WPS.
User Safety Recommendations Users should: Wash hands before eating, drinking, chewing gum, using tobacco, or using the toilet. Remove clothing/PPE immediately if pesticides get inside. Then wash thoroughly and put on clean clothing. Remove PPE immediately after handling this product. Wash the outside of gloves before removing. As soon as possible, wash thoroughly and change into clean clothing.
-3- Environmental Hazards This product is toxic to wildlife, freshwater and estuarine/marine fish and highly toxic to aquatic invertebrates. Runoff may be hazardous to aquatic organisms in neighboring areas. Exposed treated seed may be hazardous to wildlife. Do not contaminate water when disposing of equipment washwater or rinsate.
Pollinator Precautions Thiamethoxam is highly toxic to bees, and effects are possible as a result of exposure to translocated residues in blooming crops.
If treated seed is spilled outdoors or in areas accessible to birds, promptly clean up or bury to prevent ingestion.
Groundwater Advisory Mefenoxam is known to leach through soil into groundwater under certain conditions as a result of agricultural use. Use of this chemical in areas where soils are permeable, particularly where the water table is shallow, may result in groundwater contamination.
Thiamethoxam has properties and characteristics associated with chemicals detected in groundwater. This chemical may leach into the groundwater if used in areas where soils are permeable, particularly where the water table is shallow.
-4- CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY NOTICE: Read the entire Directions for Use and Conditions of Sale and Limitation of Warranty and Liability before buying or using this product. If the terms are not acceptable, return the product at once, unopened, and the purchase price will be refunded. The Directions for Use of this product must be followed carefully. It is impossible to eliminate all risks inherently associated with the use of this product. Crop injury, ineffectiveness or other unintended consequences may result because of such factors as manner of use or application, weather or crop conditions, presence of other materials or other influencing factors in the use of the product, which are beyond the control of SYNGENTA CROP PROTECTION, LLC or Seller. To the extent permitted by applicable law, Buyer and User agree to hold SYNGENTA and Seller harmless for any claims relating to such factors.
SYNGENTA warrants that this product conforms to the chemical description on the label and is reasonably fit for the purposes stated in the Directions for Use, subject to the inherent risks referred to above, when used in accordance with directions under normal use conditions. To the extent permitted by applicable law: (1) this warranty does not extend to the use of the product contrary to label instructions or under conditions not reasonably foreseeable to or beyond the control of Seller or SYNGENTA, and (2) Buyer and User assume the risk of any such use. To the extent permitted by applicable law, SYNGENTA MAKES NO WARRANTIES OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE NOR ANY OTHER EXPRESS OR IMPLIED WARRANTY EXCEPT AS WARRANTED BY THIS LABEL.
To the extent permitted by applicable law, in no event shall SYNGENTA be liable for any incidental, consequential or special damages resulting from the use or handling of this product. TO THE EXTENT PERMITTED BY APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE USER OR BUYER, AND THE EXCLUSIVE LIABILITY OF SYNGENTA AND SELLER FOR ANY AND ALL CLAIMS, LOSSES, INJURIES OR DAMAGES (INCLUDING CLAIMS BASED ON BREACH OF WARRANTY, CONTRACT, NEGLIGENCE, TORT, STRICT LIABILITY OR OTHERWISE) RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, SHALL BE THE RETURN OF THE PURCHASE PRICE OF THE PRODUCT OR, AT THE ELECTION OF SYNGENTA OR SELLER, THE REPLACEMENT OF THE PRODUCT.
SYNGENTA and Seller offer this product, and Buyer and User accept it, subject to the foregoing Conditions of Sale and Limitation of Warranty and Liability, which may not be modified except by written agreement signed by a duly authorized representative of SYNGENTA.
-5- DIRECTIONS FOR USE For commercial or on-farm use. It is a violation of federal law to use this product in a manner inconsistent with its labeling. Do not apply this product in a way that will contact workers or other persons, either directly or through drift. Only protected handlers may be in the area during application. For any requirements specific to your State or Tribe, consult the agency responsible for pesticide regulation.
FAILURE TO FOLLOW DIRECTIONS AND PRECAUTIONS ON THIS LABEL MAY RESULT IN CROP INJURY, POOR DISEASE CONTROL, AND/OR ILLEGAL RESIDUES.
Treatment of highly mechanically scarred or damaged seed, or seed known to be of low vigor and poor quality, except for the purpose of curative control of existing disease pests, may result in reduced germination and/or reduction of seed and seedling vigor. Treat using equipment similar to that planned for treating the total seed lot. Conduct germination tests on a small portion of seed before committing the total seed lot to a selected seed treatment. Due to seed quality and seed storage conditions beyond the control of Syngenta, no claims are made to guarantee the germination of carry-over treated seed.
Maximum usage when applying both metalaxyl- and mefenoxam-containing products to the same crop within the same season: Do not apply more than the maximum yearly total application rate for the active ingredient as stated on the label of the product containing the lowest yearly total on that crop.
AGRICULTURAL USE REQUIREMENTS Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR part 170. This Standard contains requirements for the protection of agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of agricultural pesticides. It contains requirements for training, decontamination, notification, and emergency assistance. It also contains specific instructions and exceptions pertaining to the statements on this label about personal protective equipment (PPE), notifications to workers, and restricted-entry interval. The requirements in this box only apply to uses of this product that are covered by the Worker Protection Standard. Do not enter or allow worker entry into treated areas during the restricted-entry interval (REI) of 48 hours.Exception: If the seed is treated with the product and the treated seed is soil-injected or soil-incorporated, the Worker Protection Standard, under certain circumstances, allows workers to enter the treated area if there will be no contact with anything that has been treated.
-6- PPE required for early entry to treated areas that is permitted under the Worker Protection Standard and that involves contact with anything that has been treated, such as plants, soil, or water is: Coveralls Chemical-resistant gloves made of polyvinyl chloride [PVC] , nitrile rubber , butyl rubber , barrier laminate, neoprene rubber mils, natural rubber , polyethylene, or Viton Shoes plus socks USE RESTRICTIONS Do not use for food, feed, or oil purposes. Store treated seed away from food and feedstuffs. Wear long-sleeved shirt, long pants and chemical-resistant gloves when handling treated seed. Treated seed exposed on soil surface may be hazardous to wildlife. Cover or collect treated seed spilled during loading and planting (such as in row ends). Do not allow children, pets, or livestock to have access to treated seed. Do not contaminate water bodies when disposing of planting equipment wash waters. Dispose of seed packaging in accordance with local requirements. Treated seed must be planted into the soil at a depth greater than 0.5 inch. For seed treated with Cruiser Vibrance Quattro, do not graze or feed livestock on treated areas for 45 days after planting. In the event of a crop failure or harvest of a crop grown from Cruiser Vibrance Quattro treated seed, the field may be replanted immediately to canola, soybean, barley, oat, rye triticale and wheat, sweet corn, and chickpea. Alfalfa, Brassica (cole) leafy vegetables, buckwheat, corn (except sweet corn), pearl millet, proso millet, popcorn, rice (dry-seeded), sorghum, teosinte, wild rice, cotton, cucurbit vegetables, dry bulb onions, fruiting vegetables, leafy vegetables, legume vegetables (except chickpea), mint (peppermint and spearmint), oil seed crops (black mustard seed, borage seed, crambe seed, field mustard seed, flax seed, Indian mustard seed, Indian rapeseed seed, peanuts, rapeseed seed, and safflower seed), root vegetables, strawberry, sunflowers, tobacco, and tuberous and corm vegetables may be planted 30 days from the date the Cruiser Vibrance Quattro treated seed was planted. For any other crop, the minimum plant back interval is 120 days from the date the Cruiser Vibrance Quattro treated seed was planted. A cover crop other than the crops listed above that is planted for erosion control or soil improvement may be planted sooner than the 120-day interval; however, the crop may not be grazed or harvested for food or feed. Do not make any soil or foliar application of products containing thiamethoxam to crops grown from seed treated with Cruiser Vibrance Quattro.
-7- Do not use at a rate that will result in more than 0.05 lb thiamethoxam per acre (22.7 grams ai/A) per year as a seed treatment application.
PRODUCT INFORMATION Cruiser Vibrance Quattro is a seed treatment product containing one insecticide active ingredient (thiamethoxam) and four fungicide active ingredients (difenoconazole, mefenoxam, fludioxonil and sedaxane). Cruiser Vibrance Quattro seed treatment protects against damage from certain early-season insects and certain seed- and soil- borne diseases of cereal crops. Difenoconazole provides protection against several seed, seedling and certain foliar disease including bunts and smuts. Mefenoxam protects against damping-off caused by Pythium. Fludioxonil provides protection against certain soil-borne and seed-borne diseases and is active against Fusarium, Rhizoctonia, and weakly pathogenic fungi such as Aspergillus and Penicillium. Sedaxane protects against Rhizoctonia and loose smuts (Ustilago). Thiamethoxam is a systemic seed treatment insecticide belonging to the neoticotinoid class of chemistry. Thiamethoxam in Cruiser Vibrance Quattro protects against aphids, wireworm and European chafer.
Cruiser Vibrance Quattro may be applied in tank mixes, or sequentially with other EPA- registered seed treatment pesticide products. If using Cruiser Vibrance Quattro in a tank mixture with other seed treatment products, observe all directions for use, crops/sites, use rates, dilution ratios, precautions, and limitations which appear on the tank-mix partner label(s). Do not exceed any label dosage and follow the most restrictive label precautions and limitations. This product must not be mixed with any product which prohibits such mixing.
MIXING INSTRUCTIONS Important:Always re-circulate Cruiser Vibrance Quattro thoroughly before using. Apply Cruiser Vibrance Quattro as a water-based slurry utilizing standard slurry seed treatment equipment which provides uniform seed coverage. Uneven or incomplete seed coverage may not give the desired level of insect and disease control.
Consult the manufacturer of the application equipment you plan to employ for suitability for this application and for instructions on operation and calibration of the equipment. Follow the manufacturer application instructions for the seed treatment equipment being used.
Continuous agitation or mixing of the slurry mixture is necessary to prevent settling out of the solution.
-8- Allow seed to dry before bagging. Follow planter manufacturer specifications for use of talc or other hopper box additives at planting. Seed must be completely dry before adding to planter.
Required Dye Statement: Seed treated with this product must be visually identifiable from untreated seed by the use of an approved colorant or dye to prevent accidental use of treated seed as food for humans or feed for animals. Refer to 21 CFR, Part 2.25. Any colorant or dye added to treated seed must be cleared for use in accordance with 40 CFR, Part 153.155(c).
-9- SEED BAG LABEL REQUIREMENTS Use of On-Farm Treated Seed (when treated seed are not for sale or distribution) Treated seed sold or distributed for a use not permitted by the following labeling does not qualify as an exempted treated article under 40 CFR 152.25(a) and is therefore sale or distribution of an unregistered pesticide, pursuant to FIFRA section 12. Store treated seed away from food and feedstuffs. DO NOTallow children, pets, or livestock to have access to treated seed. Treated seed are for planting purposes only. DO NOT use for food, feed, or oil purposes. DO NOT use treated seed for fuel or ethanol production purposes. Wear long-sleeved shirt, long pants, shoes, socks, and chemical-resistant gloves when handling treated seed. DO NOT plant treated seed by broadcasting to the soil surface. Ensure that all planted seeds are thoroughly incorporated by the planter during planting. Additional incorporation may be required to thoroughly cover exposed seeds. Treated seed exposed on the soil surface may be hazardous to wildlife. Cover or collect treated seed spilled during loading and planting (such as in row ends). Treated seed must be planted into the soil at a depth greater than 0.5 inch. Manage excess treated seed (e.g., spilled, unused, or expired treated seed) by one or more of the following methods: o Collect excess treated seed for reuse for planting. o Bury excess treated seed (only allowed if totaling 1 pound or less) at least 30 feet away from bodies of water at a depth of 6 inches or double the planting depth, whichever is greater. o Dispose of excess treated seed by placing them in a landfill in accordance with applicable laws in your state. o Return excess treated seed to the supplier if permitted by the state. DO NOTcontaminate bodies of water when disposing of equipment wash water. Advisory Dust-Reducing Technique:The use of seed flow lubricants or polymer coatings may help decrease the amount of dust released during planting. Follow the recommendations of the planter manufacturer regarding the use of seed flow lubricants.
-10- Seed Treatment in Commercial Facilities or Seed Treatment on Farm (when treated seed are to be sold or distributed) – Seed Bag Labeling Requirements The Federal Seed Act requires that bags containing treated seed shall be labeled with the following statements: This seed has been treated with difenoconazole, fludioxonil ,mefenoxam, and sedaxane fungicides and thiamethoxam insecticide. Do not use for food, feed, or oil purposes. The U.S. Environmental Protection Agency requires that bags containing treated seed shall be labeled with the following statements. Any seed treated with Cruiser Vibrance Quattro that is sold or distributed without these statements or that is sold or distributed for a use not permitted by the following labeling does not qualify as an exempted treated article under 40 CFR 152.25(a) and is therefore sale or distribution of an unregistered pesticide, pursuant to FIFRA section 12(a)(1)(A).
This seed has been treated with Cruiser Vibrance Quattro (EPA Reg No. 100-1527) containing difenoconazole, fludioxonil, mefenoxam, sedaxane, and thiamethoxam. Any seed treated with Cruiser Vibrance Quattro that is sold or distributed for a use not permitted by the following labeling does not qualify as an exempted treated article under 40 CFR 152.25(a) and is therefore sale or distribution of an unregistered pesticide, pursuant to FIFRA section 12(a)(1)(A). The contents of this bag are for planting purposes only. DO NOT use for food, feed, or oil purposes. DO NOT use for fuel or ethanol production purposes. Store treated seed away from food and feedstuffs. DO NOT allow children, pets, or livestock to have access to treated seed. DO NOT plant treated seed by broadcasting to the soil surface. Ensure that all planted seed are thoroughly incorporated by the planter during planting. Additional incorporation may be required to thoroughly cover exposed seed. Wear long-sleeved shirt, long pants and chemical-resistant gloves when handling treated seed. Treated seed exposed on soil surface may be hazardous to wildlife. Cover or collect treated seed spilled during loading and planting (such as in row ends). Do not contaminate water bodies when disposing of planting equipment wash waters. Dispose of seed packaging in accordance with local requirements. Treated seed must be planted into the soil at a depth greater than 0.5 inch. Manage excess treated seed (e.g., spilled, unused, or expired treated seed) by one or more of the following methods: o Collect excess treated seed for reuse for planting. o Bury excess treated seed (only allowed if totaling 1 pound or less) at least 30 feet away from bodies of water at a depth of 6 inches or double the planting depth, whichever is greater. o Dispose of excess treated seed by placing them in a landfill in accordance with applicable laws in your state.
-11- o Return excess treated seed to the supplier if permitted by the state. For seed treated with Cruiser Vibrance Quattro, do not graze or feed livestock on treated areas for 45 days after planting. In the event of a crop failure or harvest of a crop grown from Cruiser Vibrance Quattro treated seed, the field may be replanted immediately to canola, soybean, barley, oat, rye triticale, wheat, sweet corn, and chickpea. Alfalfa, Brassica(Cole) leafy vegetables, buckwheat, corn (except sweet corn), pearl millet, Proso millet, popcorn, rice (dry-seeded), sorghum, teosinte, wild rice, cotton, Cucurbit vegetables, dry bulb onions, fruiting vegetables, leafy vegetables, Legume vegetables (except chickpea), mint (peppermint and spearmint), oil seed crops (black mustard seed, borage seed, crambe seed, field mustard seed, flax seed, Indian mustard seed, Indian rapeseed seed, peanuts, rapeseed seed, and safflower seed), root vegetables, strawberry, sunflowers, tobacco, and tuberous and corm vegetables may be planted 30 days from the date the Cruiser Vibrance Quattro treated seed was planted. For any other crop, the minimum plant back interval is 120 days from the date the Cruiser Vibrance Quattro treated seed was planted. A cover crop other than the crops listed above that is planted for erosion control or soil improvement may be planted sooner than the 120-day interval; however, the crop may not be grazed or harvested for food or feed. Regardless of type of application (seed treatment, soil or foliar), do not apply more than 0.46 lb/A (208.7 g ai/A) difenoconazole per calendar year. Do not make any soil or foliar application of products containing thiamethoxam to crops grown from seed treated with Cruiser Vibrance Quattro. Do not apply more than 0.05 lb/A (22.7 g ai/A) thiamethoxam, 0.097 lb/A (44.0 g ai/A) mefenoxam- or metalaxyl, or 0.016 lb ai/A (7.1 g ai/A) sedaxane per year as a seed treatment application. This seed has been treated with 0.008 mg ai thiamethoxam per seed assuming an average seed size of 12,000 seeds per pound. Pollinator Precaution: Thiamethoxam is highly toxic to bees, and effects are possible as a result of exposure to translocated residues in blooming crops. Groundwater Advisory: Mefenoxam is known to leach through soil into groundwater under certain conditions as a result of agricultural use. Use of this chemical in areas where soils are permeable, particularly where the water table is shallow, may result in groundwater contamination. Thiamethoxam has properties and characteristics associated with chemicals detected in groundwater. This chemical may leach into the groundwater if used in areas where soils are permeable, particularly where the water table is shallow. Advisory Dust-Reducing Technique: The use of seed flow lubricants or polymer coatings may help decrease the amount of dust released during planting. Follow the recommendations of the planter manufacturer regarding the use of seed flow lubricants. [All seed bag tags must be legible and set in at least 8-point font size.]
-12- CROP USE PRECAUTIONS DIFENOCONAZOLE GROUP3 FUNGICIDE MEFENOXAM GROUP4 FUNGICIDE SEDAXANE GROUP 7 FUNGICIDE FLUDIOXONIL GROUP12 FUNGICIDE Fungicide Resistance Management For resistance management, please note that Cruiser Vibrance Quattro contains Group 3/difenoconazole, Group 4/mefenoxam, Group 7/sedaxane, and Group 12/fludioxonil fungicides. Any fungal population may contain individuals naturally resistant to Cruiser Vibrance Quattro and other Group 3, Group 4, Group 7, or Group 12 fungicides. A gradual or total loss of pest control may occur over time if these fungicides are used repeatedly in the same fields. Appropriate resistance-management strategies should be followed.
Difenoconazole belongs to the triazole class of chemistry and is a demethylation inhibitor of sterol biosynthesis (DMI) which disrupts membrane synthesis of the fungal cell. Mefenoxam belongs to the phenylamide class of chemistry which interferes with fungal RNA synthesis. Sedaxane is a succinate dehydrogenase inhibitor (SDHI) and belongs to the carboxamide class of chemistry which disrupts cellular respiration and energy generation. Fludioxonil belongs to the phenylpyrrole class of chemistry which interferes with osmotic signal transduction.
To delay fungicide resistance, take one or more of the following steps:
Rotate the use of Cruiser Vibrance Quattro or other Group 3, Group 4, Group 7, or Group 12 fungicides within a growing season sequence with different groups that control the same pathogens. Use tank mixtures with fungicides from a different group that are equally effective on the target pest when such use is permitted. Use at least the minimum application rate as labeled by the manufacturer. Adopt an integrated disease management program for fungicide use that includes scouting, uses historical information related to pesticide use, and crop rotation, and which considers host plant resistance, impact of environmental conditions on disease development, disease thresholds, as well as cultural, biological and other chemical control practices. Where possible, make use of predictive disease models to effectively time fungicide application. Note that using predictive models alone is not sufficient to manage resistance. Monitor treated fungal populations for resistance development.
-13- Contact your local extension specialist or certified crop advisor for any additional pesticide resistance-management and/or IPM recommendations for specific crops and pathogens. For further information or to report suspected resistance contact Syngenta at 1- 866-SYNGENT(A) (866-796-4368). You can also contact your pesticide distributor or university extension specialist to report resistance. Syngenta encourages responsible product stewardship to ensure effective long term control of the fungal diseases on this label. THIAMETHOXAM GROUP4A INSECTICIDE Insecticide Resistance Management For resistance management, note that Cruiser Vibrance Quattro contains a Group 4A insecticide (thiamethoxam, belonging to the neonicotinoid class of chemistry). Any insect population may contain individuals naturally resistant to Cruiser Vibrance Quattro and other Group 4A insecticides. The resistant individuals may dominate the insect population if these insecticides are used repeatedly in the same fields. Appropriate resistance-management strategies should be followed.
To delay insecticide resistance, take the following steps: Rotate the use of Cruiser Vibrance Quattro or other Group 4A insecticides within a growing season, or among growing seasons, with different groups that control the same pests. Use tank mixtures with insecticides from a different group that are equally effective on the target pest when such use is permitted. Do not rely on the same mixture repeatedly for the same pest population. Consider any known cross-resistance issues (for the targeted pests) between the individual components of a mixture. In addition, consider the following recommendations provided by the Insecticide Resistance Action Committee (IRAC): o Individual insecticides selected for use in mixtures should be highly effective and be applied at the rates at which they are individually registered for use against the target species. o Mixtures with components having the same IRAC mode of action classification are not recommended for insect resistance management. o When using mixtures, consider any known cross-resistance issues between the individual components for the targeted pest(s). o Mixtures become less effective if resistance is already developing to one or both active ingredients, but they may still provide pest management benefits. o The insect resistance management benefits of an insecticide mixture are greatest if the two components have similar periods of residual insecticidal activity. Mixtures of insecticides with unequal periods of residual insecticide activity may offer an insect resistance management benefit only for the period where both insecticides are active.
-14- Adopt an integrated pest management program for insecticide use that includes scouting, uses historical information related to pesticide use, crop rotation, record keeping, and which considers cultural, biological and other chemical control practices. Monitor after application for unexpected target pest survival. If the level of survival suggests the presence of resistance, consult with your local university specialist or certified pest control advisor. Contact your local extension specialist or certified crop advisors for any additional pesticide resistance-management and/or IPM recommendations for the specific site and pest problems in your area. For additional information on Insect Resistance Management: Contact your local extension specialist, certified crop advisor and/or product manufacturer for additional insect resistance management recommendations. Visit the Insecticide Resistance Action Committee (IRAC) on the web at: http://www.irac-online.org/.
-15- CROP USE DIRECTIONS Crop Protection Against the following Insects Use Rate Fluid Ounces per 100 lb seed Barley Aphids1 European Chafer Wireworms1 5 fluid oz Crop Protection Against the Following Diseases Use Rate Fluid Ounces per 100 lb seed Barley General Seed Rots2 Seedling Blight, Root Rot, and Damping-Off caused by seed- and soil-borne Fusarium . or Rhizoctonia Seedling Blight, Root Rot, and Damping-Off caused by soil-borne Pythium Seed-borne Septoria Covered Smut False Loose Smut True Loose Smut 5 fluid oz Crop Diseases Suppressed3 Use Rate Fluid Ounces per 100 lb seed Barley Common Root Rot (Cochliobolus ) Fusarium Crown and Foot Rot Take-All 5 fluid oz Crop Protection Against the following Insects Use Rate Fluid Ounces per 100 lb seed Oats Aphids1 European Chafer Wireworms1 5 fluid oz Crop Protection Against the Following Diseases Use Rate Fluid Ounces per 100 lb seed Oats General Seed Rots2 Seedling Blight, Root Rot, and Damping-Off caused by seed- and soil-borne Fusarium or Rhizoctonia Seedling Blight, Root Rot, and Damping-Off caused by soil-borne Pythium Seed-borne Septoria Covered Smut Loose Smut 5 fluid oz Crop Diseases Suppressed3 Use Rate
-16- Fluid Ounces per 100 lb seed Oats Common Root Rot (Cochliobolus) 5 fluid oz Crop Protection Against the following Insects Use Rate Fluid Ounces per 100 lb seed Rye Aphids1 European Chafer Wireworms1 5 fluid oz Crop Protection Against the Following Diseases Use Rate Fluid Ounces per 100 lb seed Rye General Seed Rots2 Seedling Blight, Root Rot, and Damping-Off caused by seed- and soil-borne Fusarium or Rhizoctonia Seedling Blight, Root Rot, and Damping-Off caused by soil-borne Pythium Seed-borne Septoria Common Bunt4 Dwarf Bunt4 5 fluid oz Crop Diseases Suppressed3 Use Rate Fluid Ounces per 100 lb seed Rye Common Root Rot (Cochliobolus) Fusarium Crown and Foot Rot Take-All 5 fluid oz Crop Protection Against the following Insects Use Rate Fluid Ounces per 100 lb seed Winter Wheat Aphids1 European Chafer Wireworms1 5 fluid oz Crop Protection Against the Following Diseases Use Rate Fluid Ounces per 100 lb seed Winter Wheat and Triticale General Seed Rots2 Seedling Blight, Root Rot, and Damping-Off caused by seed- and soil-borne Fusarium or Rhizoctonia Seedling Blight, Root Rot, and Damping-Off caused by soil-borne Pythium Seed-borne Septoria SeptoriaLeaf Blotch5 Common Bunt4 Flag Smut Fusarium Seed Scab 5 fluid oz
-17- Dwarf Bunt4 Karnal Bunt Loose Smut PythiumDamping Off Crop Diseases Suppressed3 Use Rate Fluid Ounces per 100 lb seed Winter Wheat and Triticale Common Root Rot (Cochliobolus) Fusarium Crown and Foot and Root Rot Take-All 5 fluid oz Crop Protection Against the following Insects Use Rate Fluid Ounces per 100 lb seed Spring Wheat Aphids1 European Chafer Wireworms1 5 fluid oz Crop Protection Against the Following Diseases Use Rate Fluid Ounces per 100 lb seed Spring Wheat General Seed Rots2 Seedling Blight, Root Rot, and Damping-Off caused by seed- and soil-borne Fusarium or Rhizoctonia Seedling Blight, Root Rot, and Damping-Off caused by soil-borne Pythium Seed-borne Septoria Fusarium Seed Scab Common Bunt4 Karnal Bunt Loose Smut Pythium Damping Off 5 fluid oz Crop Diseases Suppressed3 Use Rate Fluid Ounces per 100 lb seed Spring Wheat Common Root Rot (Cochliobolus ) Fusarium Crown and Foot and Root Rot Take-All 5 fluid oz 1The 5 fluid oz/100 lbs rate of Cruiser Vibrance Quattro provides suppression of wireworm activity, aphids and aphid vectored barley yellow dwarf virus. If pressure is moderate or high or control is required, apply up to 0.8 fl. oz. additional Cruiser 5FS. 2Protection against general seed rots. This includes rots caused by Fusarium , Pythium , Rhizoctonia , Penicillium and Aspergillus . 3Suppression means consistent protection at a level which is not optimal but is still of commercial benefit. 4Protects against both seed- and soil-borne bunts (common, dwarf). 5Early season foliar disease protection for first 4 weeks after planting. For full season protection, apply a foliar fungicide according to label directions.
-18- STORAGE AND DISPOSAL Do not contaminate water, food or feed by storage and disposal. Pesticide Storage Store in original containers only. Keep container closed when not in use. Do not store near food or feed. In case of spill on floor or paved surfaces, mop and remove to chemical waste storage area until proper disposal can be made if product cannot be used according to the label. Pesticide Disposal Pesticide wastes are toxic. Improper disposal of excess pesticide, spray mixture, or rinsate is a violation of Federal law. If these wastes cannot be disposed of by use according to label instructions, contact your State Pesticide or Environmental Control Agency, or the Hazardous Waste representative of the nearest EPA Regional Office for guidance. Container Handling [(less than 5 gallons)] Non-refillable container. Do not reuse or refill this container. Offer for recycling if available. Triple rinse container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank and drain for 10 seconds after the flow begins to drip. Fill the container ¼ full with water and recap. Shake for 10 seconds. Pour rinsate into application equipment or a mix tank or store rinsate for later use and disposal. Drain for 10 seconds after the flow beings to drip. Repeat this procedure two more times. Then offer for recycling if available or puncture and dispose of in a sanitary landfill, or by incineration, or by other procedures allowed by state and local authorities. Container Handling [(greater than 5 gallons)] Non-refillable container. Do not reuse or refill this container. Offer for recycling if available. Triple rinse container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank. Fill the container ¼ full with water. Replace and tighten closures. Tip container on its side and roll it back and forth, ensuring at least one complete revolution, for 30 seconds. Stand the container on its end and tip it back and forth several ties. Turn the container over onto its other end and tip it back and forth several times. Empty the rinsate into application equipment or a mix tank or store rinsate for later use or disposal. Repeat this procedure two more times. Then offer for recycling if available or puncture and dispose of in a sanitary landfill, or by incineration, or by other procedures allowed by state and local authorities. Container Handling [(greater than 5 gallons)] Refillable container. Refill this container with pesticide only. Do not use this container for any other purpose. Cleaning the container before final disposal is the responsibility of the person disposing of the container. Cleaning before refilling is the responsibility of the refiller. To clean container before final disposal, empty the remaining contents from this
-19- container into application equipment or mix tank. Fill the container about 10 percent full with water. Agitate vigorously or recirculate water with the pump for 2 minutes. Pour or pump rinsate into application equipment or rinsate collection system. Repeat this rinsing procedure two more times. Then offer for recycling if available or puncture and dispose of in a sanitary landfill, or by incineration, or by other procedures allowed by state and local authorities. CONTAINER IS NOT SAFE FOR FOOD, FEED OR DRINKING WATER. Cruiser®, Vibrance®, the ALLIANCE FRAME, the SYNGENTA Logo and the PURPOSE ICON are Trademarks of a Syngenta Group Company Viton™ is a trademark of The Chemours Company FC, LLC © 20XX Syngenta For non-emergency (e.g., current product information) call Syngenta Crop Protection at 1-866-796-4368. Manufactured for: Syngenta Crop Protection, LLC P.O. Box 18300 Greensboro, North Carolina 27419-8300
Cruiser Vibrance Quattro 1527 MAS 0919 AMEND-B FEB2026-CL – jeb – 05/18/2026 000100-01527.20260216B.Cruiser Vibrance Quattro.AMEND.FEB2026-CL.PDF