crop-chem-docs/corpus/epa_ppls/264-1195.md

#  Osprey Xtra Herbicide

- EPA Reg No: **264-1195**
- Registrant: BAYER CROPSCIENCE, LLC
- Signal word: Caution
- Active ingredients: Thiencarbazone-methyl (1.5%); Mesosulfuron-methyl (4.5%)
- Label accepted: 2024-11-18
- Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000264-01195-20241118.pdf

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November 18, 2024 
 
Gaganpreet Kaur 
Senior Regulatory Affairs Manager 
Bayer CropScience LP 
800 N. Lindbergh Blvd. 
St. Louis, MO 63167 
 
Subject: Label Amendment - Registration Review Mitigation for Mesosulfuron-methyl & 
Thiencarbazone-methyl 
 Product Name: Osprey Xtra Herbicide 
 EPA Registration Number: 264-1195 
Application Dates: January 26, 2020; October 26, 2020; January 26, 2021; & June 
28, 2022 
Decision Numbers: 567263 & 569981 
Case Numbers: 480694 & 476734 
 
Dear Gaganpreet Kaur: 
 
The Agency, in accordance with the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), 
as amended, has completed reviewing all the information submitted with your application to 
support the Registration Review of the above referenced product in connection with the 
Mesosulfuron-methyl and Thiencarbazone-methyl Interim Decisions, and has concluded that 
your submission is acceptable. The label referred to above, submitted in connection with 
registration under FIFRA, as amended, is acceptable. 
 
Should you wish to add/retain a reference to the company’s website on your label, then please 
be aware that the website becomes labeling under the Federal Insecticide, Fungicide, and 
Rodenticide Act and is subject to review by the Agency. If the website is false or misleading, the 
product would be misbranded and unlawful to sell or distribute under FIFRA section 12(a)(1)(E). 
40 CFR 156.10(a)(5) list examples of statements EPA may consider false or misleading. In 
addition, regardless of whether a website is referenced on your product’s label, claims made on 
the website may not substantially differ from those claims approved through the registration 
process. Therefore, should the Agency find or if it is brought to our attention that a website 
contains false or misleading statements or claims substantially differing from the EPA approved 
registration, the website will be referred to the EPA’s Office of Enforcement and Compliance 
Assurance.

Page 2 of 2 
EPA Reg. No. 264-1195 
Decision No. 567263 & 569981 
 
A stamped copy of your labeling is enclosed for your records. This labeling supersedes 
all previously accepted labeling and must be used at your next label printing. You must 
submit one copy of the final printed labeling before you release the product for 
shipment with the new labeling. In accordance with 40 CFR 152.130(c), you may 
distribute or sell this product under the previously approved labeling for 12 months 
from the date of this letter. After 12 months, you may only distribute or sell this 
product if it bears this new revised labeling or subsequently approved labeling. “To 
distribute or sell” is defined under FIFRA section 2(gg) and its implementing regulation 
at 40 CFR 152.3. 
 
If you have any questions about this letter, please contact Caleb Carr by phone at (202) 566-
0636, or via email at carr.caleb@epa.gov. 
 
 Sincerely, 
 
 
 Linda Arrington, Branch Chief 
 Risk Management and Implementation Branch 4 
 Pesticide Re-Evaluation Division 
 Office of Pesticide Programs 
 
 
 
ENCLOSURE: Stamped label

1
OSPREY® Xtra Herbicide
For: The Control of Annual Grass and Broadleaf Weeds in Fall-Sown or Winter Wheat and Fall-Sown Triticale.
ACTIVE INGREDIENT:
Mesosulfuron-Methyl............................................................................................................ ............................................................... 4.50%
Thiencarbazone-Methyl………..……………………………………………………………………………………………………………….. 1.50%
OTHER INGREDIENTS: ............................................................................................................................. ..................................... 94.00%
TOTAL: 100.00% 
This product is a water dispersible granule containing 4.5% of active ingredient, mesosulfuron-methyl and 1.5% of active 
ingredient thiencarbazone-methyl by weight.
EPA Reg. No. 264-1195 EPA Est. 
KEEP OUT OF REACH OF CHILDREN
CAUTION
For MEDICAL and TRANSPORTATION Emergencies ONLY Call 24 Hours a Day 1-800-334-7577
For PRODUCT USE Information Call 1-866-99BAYER (1-866-992-2937)
Please refer to [back panel] [booklet] for additional precautionary statements and directions for use. [Note to 
reviewer: Location of additional precautionary statements and directions for use will vary between those listed, 
depending on container type/size.]
Net Contents: 
[Batch Code:]
PRODUCED FOR
Bayer CropScience LP
800 N. Lindbergh Blvd.
St. Louis, MO 63167
1-866-99BAYER (1-866-992-2937)
MESOSULFURON-METHYL GROUP 2 HERBICIDE
THIENCARBAZONE-METHYL GROUP 2 HERBICIDE
Nov 18, 2024
264-1195

2 
 
FIRST AID 
If Swallowed: x Immediately call a poison control center or doctor for treatment advice. 
x Do not induce vomiting unless told to do so by a poison control center or doctor. 
x Do not give anything by mouth to an unconscious person. 
x Have person sip a glass of water if able to swallow. 
If in Eyes: x Hold eye open and rinse slowly and gently with water for 15-20 minutes. 
x Remove contact lenses, if present, after the first 5 minutes, and then continue rinsing. 
x Call a poison control center or doctor for treatment advice. 
In case of emergency, call the toll-free Bayer CropScience Emergency Response telephone number: 1-800-334-7577. 
Have a product container or label with you when calling a poison control center or doctor, or going for treatment. 
 
 
PRECAUTIONARY STATEMENTS 
 
HAZARDS TO HUMANS AND DOMESTIC ANIMALS 
CAUTION 
x Harmful if swallowed. 
x Causes moderate eye injury. 
x Avoid contact with eyes or clothing. 
x Wash thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco, or using the 
toilet. 
x Remove and wash contaminated clothing before reuse. 
 
PERSONAL PROTECTIVE EQUIPMENT (PPE) 
 
Applicators and other handlers must wear: 
x Long-sleeved shirt and long pants 
x Shoes plus socks 
x Waterproof gloves 
x Protective eyewear (safety glasses) 
 
ENGINEERING CONTROLS 
When handlers use closed systems, enclosed cabs or aircraft in a manner that meets the requirements listed in the Worker Protection 
Standard (WPS) for agricultural pesticides [40 CFR 170.240 (d)(4-6)], the handler PPE requirements may be reduced or modified as 
specified in the WPS. 
 
USER SAFETY REQUIREMENTS 
Follow manufacturer's instructions for cleaning/maintaining PPE. If no such instructions for washables exist, use detergent and hot water. 
Keep and wash PPE separately from other laundry. 
USER SAFETY RECOMMENDATIONS 
x Users should remove clothing/PPE immediately if pesticide gets inside. Then wash thoroughly and put on clean clothing. 
x Users should remove PPE immediately after handling this product. Wash the outside of gloves before removing. As soon as 
possible, wash thoroughly and change into clean clothing. 
 
ENVIRONMENTAL HAZARDS 
For terrestrial uses: Do not apply directly to water, or to areas where surface water is present or to intertidal areas below the mean high 
water mark. Do not contaminate water when disposing of equipment washwater or rinsate. 
 
Groundwater Advisory: This chemical has properties and characteristics associated with chemicals detected in groundwater. This 
chemical may leach into groundwater if used in areas where soils are permeable, particularly where the water table is shallow. 
 
Surface Water Advisory: This product may impact surface water quality due to runoff of rainwater. This is especially true for poorly 
draining soils and soils with shallow groundwater. This product is classified as having high potential for reaching surface water via runoff

3 
 
for several months or more after application. A level, well-maintained vegetative buffer strip between areas to which this product is 
applied and surface water features such as ponds, streams, and springs will reduce the potential loading of mesosulfuron-methyl and 
thiencarbazone-methyl from runoff water and sediment. Runoff of this product will be greatly reduced by avoiding applications when 
rainfall or irrigation is expected to occur within 48 hours. 
Non-Target Organism Advisory: This product is toxic to plants and may adversely impact the forage and habitat of non-target 
organisms, including pollinators, in areas adjacent to the treated site. Protect the forage and habitat of non-target organisms by following 
label directions intended to minimize spray drift. 
Endangered Species Protection Requirements 
It is a Federal offense to use any pesticide in a manner that results in an unauthorized “take” (e.g., kill or otherwise harm) of an 
endangered species, and certain threatened species, under the Endangered Species Act section 9. When using this product, you must 
follow the measures contained in the Endangered Species Protection Bulletin for the area in which you are applying the product. You 
must obtain a Bulletin no earlier than six months before using this product. To obtain Bulletins, consult http://www.epa.gov/espp/, call 1-
844-447-3813, or email ESPP@epa.gov. You must use the Bulletin valid for the month in which you will apply the product. 
 
Reporting Ecological Incidents: 
To report ecological incidents, including mortality, injury, or harm to plants and animals, call 1-866-99BAYER (1-866-992-2937) 
 
To avoid adverse effects on endangered dicot species, the following mitigation measures will be required where endangered species 
occur in Counties listed in the table below. 
 
For ground applications, the applicator must: 
x Apply when there is sustained wind away from native plant communities, OR 
x Use low-pressure nozzles according to manufacturer's specif ications that produce only coarse or very coarse droplets 
x Leave 50 foot untreated buffer between treatment area and native plant communities. 
 
For aerial applications, the applicator must: 
x Apply only when there is sustained wind away from native plant communities 
x Leave 350 foot untreated buffer between treatment area and native plants. 
 
 
State County State County State County 
Idaho Idaho 
Lewis 
Nez Perce 
Oregon Benton 
Clackamas 
Lane
 
Linn 
Marion 
Polk 
Union 
Wallowa 
Washington 
Yamhill 
Washington Asotin 
Chelan 
Cowlitz 
Lewis 
Lincoln 
Spokane 
Whitman 
Montana Flathead 
Lake 
Wyoming Laramie

4 
 
DIRECTIONS FOR USE 
 
It is a violation of Federal law to use this product in a manner inconsistent with its labeling. 
Read the entire label before using this product. 
 
Do not apply this product in a way that will contact workers or other persons, either directly or through drift. Only protected handlers may 
be in the area during application. For any requirements specific to your State or Tribe, consult the agency responsible for pesticide 
regulation. 
 
For Important crop safety information, refer to the Use Directions section under the specific crop. 
 
OSPREY
® Xtra Herbicide is not registered for use in Minnesota. 
 
AGRICULTURAL USE REQUIREMENTS 
Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR part 170. This Standard 
contains requirements for the protection of agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of 
agricultural pesticides. It contains requirements for training, decontamination, and emergency assistance. It also contains specific 
instructions and exceptions pertaining to the statements on this label about personal protective equipment (PPE), notification to 
workers, and restricted-entry interval. The requirements in this box only apply to uses of this product that are covered by the Worker 
Protection Standard. 
 
Do not enter or allow worker entry into treated areas during the restricted entry interval 
(REI) of 4 hours. 
 
PPE required for early entry
 to treated areas (that is permitted under the Worker Protection Standard and that involves 
contact with anything that has been treated, such as plants, soil, or water), is: 
x Coveralls. 
x Socks, shoes 
x Waterproof gloves 
x Protective eyewear 
 
PRODUCT INFORMATION 
OSPREY Xtra Herbicide: 
x Is intended for application as a foliar spray in fall-sown or winter wheat or fall-sown triticale for the control of annual grass and 
broadleaf weeds. Best weed control is obtained when OSPREY Xtra Herbicide is applied to young actively growing weeds in 
vigorously growing fall sown or winter wheat that will shade competitive weeds. 
x Is absorbed through the foliage of plants, rapidly inhibiting growth of susceptible weeds. Visual symptoms progress from 
yellowing to necrosis of the growing point and eventual plant death. Abnormal environmental conditions (excess soil moisture or 
drought, extreme cold weather) can influence crop tolerance and herbicidal activity and may cause temporary damage to the 
crop or reduce levels of weed control. This may result in weed stunting, rather than weed death. However, weed competition 
will be greatly reduced, and should permit normal crop development. Crop response may occur when frost occurs shortly after 
application to actively growing wheat. 
x Is rainfast 4 hours after application to most weed species. Rainfall within 4 hours may result in reduced weed control. 
 
MANDATORY SPRAY DRIFT MANAGEMENT 
 
Aerial Applications: 
x Nozzles must be oriented so the spray is directed toward the back of the aircraft. 
x Do not release spray at a height greater than 10 ft above the ground or vegetative canopy, unless a greater application 
height is necessary for pilot safety. 
x Applicators are required to use a medium or coarser droplet size (ANSI/ASABE S641) for all applications. 
x Applicators must use ½ swath displacement upwind at the downwind edge of the field. 
x Do not apply when wind speeds exceed 10 mph at the application site. The boom length must not exceed 65% of the 
wingspan for airplanes or 75% of the rotor blade diameter for helicopters. 
x Do not apply during temperature inversions. 
 
Ground Boom Applications: 
x Apply with the nozzle height recommended by the manufacturer, but no more than 3 feet above the ground or crop canopy. 
x Applicators are required to use a medium or coarser droplet size (ANSI/ASAE S572.3). 
x Do not apply during temperature inversions. 
x Do not apply when wind speeds exceed 10 miles per hour at the application site.

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Spray Drift Advisories 
THE APPLICATOR IS RESPONSIBLE FOR AVOIDING OFF-SITE SPRAY DRIFT. BE AWARE OF NEARBY NON-
TARGET SITES AND ENVIRONMENTAL CONDITIONS. 
 
Importance Of Droplet Size 
An effective way to reduce spray drift is to apply large droplets. Use the largest droplets that provide target pest control. While applying 
larger droplets will reduce spray drift, the potential for drift will be greater if applications are made improperly or under unfavorable 
environmental conditions. 
 
Ground Boom 
Controlling Droplet Size 
x Volume - Increasing the spray volume so that larger droplets are produced will reduce spray drift. Use the highest practical 
spray volume for the application. If a greater spray volume is needed, consider using a nozzle with a higher flow rate. 
x Pressure - Use the lowest spray pressure recommended for the nozzle to produce the target spray volume and droplet size. 
x Spray Nozzle - Use a spray nozzle that is designed for the intended application. Consider using nozzles designed to reduce 
drift. 
Boom Height 
x For ground equipment, the boom should remain level with the crop and have minimal bounce. 
 
Aircraft 
Controlling Droplet Size 
x Adjust Nozzles - Follow nozzle manufacturer’s recommendations for setting up nozzles. Generally, to reduce fine droplets, 
nozzles should be oriented parallel with the airflow in flight. 
Release Height 
x Higher release heights increase the potential for spray drift. 
 
Shielded Sprayers 
Shielding the boom or individual nozzles can reduce spray drift. Consider using shielded sprayers. Verify that the shields are not 
interfering with the uniform deposition of the spray on the target area. 
 
Temperature And Humidity 
When making applications in hot and dry conditions, use larger droplets to reduce effects of evaporation. 
 
Temperature Inversions 
Drift potential is high during a temperature inversion. Temperature inversions are characterized by increasing temperature with altitude 
and are common on nights with limited cloud cover and light to no wind. The presence of an inversion can be indicated by ground fog or 
by the movement of smoke from a ground source or an aircraft smoke generator. Smoke that layers and moves laterally in a 
concentrated cloud (under low wind conditions) indicates an inversion, while smoke that moves upward and rapidly dissipates indicates 
good vertical air mixing. Avoid applications during temperature inversions. 
 
Wind 
Drift potential generally increases with wind speed. AVOID APPLICATIONS DURING GUSTY WIND CONDITIONS. Applicators need to 
be familiar with local wind patterns and terrain that could affect spray drift. 
 
Windblown Soil Particles 
OSPREY Xtra Herbicide has the potential to move off-site due to wind erosion. Soils that are subject to wind erosion usually have a high 
silt and/or fine to very fine sand fractions and low organic matter content. Other factors which can affects the movement of windblown 
soil include the intensity and direction of prevailing winds, vegetative cover, site slope, rainfall, and drainage patterns. Avoid applying 
OSPREY Xtra Herbicide if prevailing local conditions may be expected to result in off-site movement. 
 
WEED RESISTANCE MANAGEMENT 
For resistance management, OSPREY Xtra Herbicide is a Group 2 herbicide. Any weed population may contain or develop plants 
naturally resistant to OSPREY Xtra Herbicide and other Group 2 herbicides. The resistant biotypes may dominate the weed population if 
these herbicides are used repeatedly in the same field. Appropriate resistance management strategies should be followed. 
To delay herbicide resistance take one or more of the following steps: 
x Rotate the use of OSPREY Xtra Herbicide or other Group 2 he rbicides within a growing season sequence or among growing 
seasons with different herbicide groups that control the same weeds in a field. 
x Use tank mixtures with herbicides from a different group if such use is permitted; where information on resistance in target 
weed species is available, use the less resistance-prone partner at a rate that will control the target weed(s) equally as well as

6 
 
the more resistance-prone partner. Consult your local extension service or certified crop advisor if you are unsure as to which 
active ingredient is currently less prone to resistance. 
x Adopt an integrated weed-management program for herbicide use th at includes scouting and uses historical information related 
to herbicide use and crop rotation, and that considers tillage ( or other mechanical control methods), cultural ( e.g., higher crop 
seeding rates; precision fertilizer application method and timing to favor the crop and not the weeds), biological (weed-
competitive crops or varieties) and other management practices. 
x Scout after herbicide application to monitor weed populations for early signs of resistance development. Indicators of possibl e 
herbicide resistance include: (1) failure to control a weed species normally controlled by the herbicide at the dose applied, 
especially if control is achieved on adjacent weeds; (2) a spreading patch of non-controlled plants of a particular weed species; 
(3) surviving plants mixed with controlled individuals of the same species. If resistance is suspected, prevent weed seed 
production in the affected area by an alternative herbicide from a different group or by a mechanical method such as hoeing or 
tillage. Prevent movement of resistant weed seeds to other fields by cleaning harvesting and tillage equipment when moving 
between fields, and planting clean seed. 
x If a weed pest population continues to progress after treatment with this product, discontinue use of this product, and switch to 
another management strategy or herbicide with a different mode of action, if available. 
x Contact your local extension specialist or certified crop advisors for additional pesticide resistance-management and/or 
integrated weed-management recommendations for specific crops and weed biotypes. 
x For further information or to report suspected resistance co ntact Bayer CropScience at 1-866-99BAYER (1-866-992-2937). You 
can also contact your pesticide distributor or university extension specialist to report resistance. 
 
USE RESTRICTIONS 
x Do not apply OSPREY Xtra Herbicide to crops under sown with grass and legume species. 
x Do not apply when wind causes drift to off-site vegetation as injury may occur. Small amounts of OSPREY Xtra Herbicide via 
drift or tank contamination can cause severe damage to crops other than wheat. Careful management of spray drift and tank 
cleanout is required. 
x Do not apply in combination with Dicamba containing products as grass control will be reduced. 
x Do not apply OSPREY Xtra Herbicide through any type of irrigation system. 
x Do not drain or rinse equipment near desirable vegetation. 
x Do not harvest wheat for grain or straw within 60 days after ap plication in Montana, North Dakota, or South Dakota; and within 
70 days in all other states. 
x Do not apply OSPREY Xtra Herbicide within 30 days of harvesti ng or grazing wheat or triticale forage, and 60 days for hay, 
grain, and straw. 
x Do not apply OSPREY Xtra Herbicide in tank mixture with malathion, mancozeb, Di-Syston or methyl parathion as 
unacceptable crop phytotoxicity may occur. 
x Only make applications of OSPREY Xtra Herbicide in California from emergence to 2-tiller wheat (Feekes 5). 
x Do not apply more than 0.053 pounds of mefenpyr-diethyl per acre per year. 
x Do not make more than one application of OSPREY Xtra Herbicide per year. 
x Do not apply more than 4.75 oz/acre of OSPREY Xtra Herbicide in one fall sown or winter wheat or fall sown triticale growing 
season. 
 
Refer to the specific use directions and restrictions in each Crop Subgroup table. 
 
USE PRECAUTIONS 
x Applications should be made to actively growing weeds. Weed control may be reduced when weeds are under stress due to 
severe weather conditions, drought, very cold temperatures, etc. Weed control may be reduced if the herbicide application is 
made under dry, dusty conditions – especially in the wheel track areas. 
x Applications of ammonium nitrogen fertilizer independent of those made with herbicides are commonly known as top-dress 
applications. Top-dress applications of ammonium nitrogen have been shown on occasion to result in transient leaf burn or 
stunting when applied within 14 days of an OSPREY Xtra Herbicide application. 
x Avoid spray drift from treated areas. Refer to the Spray Dr ift section of this label for additional information. 
x Non-target plants may be adversely affected if the pesticide is allowed to drift from areas of application. To prevent damage to 
crops and other desirable plants, read and follow all directions and precautions on this label before using. 
x Environmental conditions which support vigorous growth of crop and weeds also result in highest herbicidal activity. Following 
application, symptoms of herbicidal activity may develop within several days. Speed of action depends on environmental 
conditions and increases with increasing temperature and moisture. 
x Use adjuvants as specified on this label. 
 
APPLICATION INSTRUCTIONS 
Uniform, thorough spray coverage is important to achieve consistent weed control. The use of nozzles and spray pressure that deliver 
MEDIUM or coarser spray droplets as indicated in the nozzle manufacturer’s catalogs and in accordance with ANSI/ ASAE Standard S-
572.3 are highly recommended for optimum spray coverage and canopy penetration. Do not use flood-jet nozzles, controlled droplet 
application equipment, or cone nozzles. Use of certain nozzle types, as described in the Spray Drift section of this label, may result in 
reduced coverage and weed control.

7 
 
Ground Application 
OSPREY Xtra Herbicide can be applied broadcast in 10 or more gallons of water per acre. For weed control in dense weed canopies, 
use 15 or more gallons of water per acre. Weed infestations should be treated before they become competitive with the crop. 
 
The use of 80-degree or 110-degree flat-fan nozzles is highly recommended for optimum spray coverage and canopy penetration. Use a 
spray pressure of 35 to 40 pounds per square inch (measured at the nozzle). Use screens that are 50 mesh or larger. 
 
Do not apply this product through any type of irrigation system. 
 
Aerial Application 
Calibrate the spray equipment prior to use. OSPREY Xtra Herbicide should be applied in a minimum of 5 gallons of water per broadcast 
acre. The use of nozzles and spray pressure that deliver MEDIUM or COARSER spray droplets as indicated in the nozzle 
manufacturer’s catalogs and in accordance with ANSI/ASABE Standard S641 are highly recommended for optimum spray coverage and 
canopy penetration. DO NOT use raindrop nozzles. Aerial applications with this product should be made at a maximum height of 10 feet 
above the crop with low drift nozzles at a maximum pressure of 40 psi. Avoid application under conditions where uniform coverage 
cannot be obtained or where excessive spray drift may occur. 
 
Flagmen and loaders should avoid inhalation of spray mist and prolonged contact with skin. 
 
See the Spray Drift section of this label for additional information on proper application of OSPREY Xtra Herbicide. 
 
MIXING, COMPATIBILITY TESTING AND TANK MIX PARTNERS 
OSPREY Xtra Herbicide must be applied with clean and properly calibrated equipment. Prior to adding OSPREY Xtra Herbicide to the 
spray tank, ensure that the spray tank, filters, and nozzles have been thoroughly cleaned. 
 
It is the pesticide user’s responsibility to ensure that all products are registered for the intended use. Read and follow the applicable 
restrictions and limitations and directions for use on all product labels involved in tank mixing. Users must follow the most restrictive 
directions for use and precautionary statements of each product in the tank mixture. 
 
Compatibility 
OSPREY Xtra Herbicide is physically and biologically compatible with many registered pesticides and fertilizers or micronutrients. 
However, there is potential for adverse chemical reactions. It is impossible to determine physical, biological, and plant compatibility for all 
scenarios that may be encountered; therefore, it is recommended that users determine the chemical, physical, biological and plant 
compatibility of such mixes prior to making applications on a broad commercial scale. 
 
If OSPREY Xtra Herbicide is to be tank mixed with other products, compatibility should be tested prior to mixing. To test for compatibility, 
use a small container and mix a small amount (0.5 to 1 qt) of spray solution, combining all ingredients in the same ratio as the 
anticipated use. If any indications of physical incompatibility develop, do not use this mixture for spraying. Indications of incompatibility 
usually occur within 5-15 minutes after mixing. Read and follow the label of each tank mix product used for precautionary statements, 
directions for use, geographic and other restrictions. 
 
Order of Mixing 
OSPREY Xtra Herbicide may be used with other recommended pesticides, fertilizers, and micronutrients. The proper mixing procedure 
for OSPREY Xtra Herbicide alone or in tank mix combinations with other pesticides is as follows: 
1. Fill the tank 1/4 to 1/3 full of water. 
2. While agitating, add the required amount of OSPREY
 Xtra Herbicide. 
3. Continue agitation until the OSPREY Xtra Herbicide is fully dispersed, at least 5 minutes. 
4. Once OSPREY Xtra Herbicide is fully dispersed, maintain agitation and continue filling tank with water. OSPREY Xtra Herbicide 
should be fully mixed with water before adding any other material 
5. As the tank is filling, add the required amount of spray adju vant and ammonium nitrogen fertilizer. Add additional pesticide tank 
mix partners, if desired. 
6. Continue agitation during herbicide application to ensure unif orm spray coverage. If the mixture is not continuously agitated, 
settling may occur. If settling occurs, thoroughly re-agitate spray solution for at least 10 minutes before application. Use spray 
solution within 24 hours after mixing. 
 
NOTE: Do not use PVA packets in a tank mix with products that contain boron or release free chlorine. The resultant reaction of PVA 
and boron or free chlorine is a plastic that is not soluble in water or solvents. 
 
RE-SUSPENDING WG PRODUCTS IN SPRAY SOLUTION 
Like other Water Dispersible Granules or suspension concentrates (SCs), OSPREY Xtra Herbicide will settle if left standing without 
agitation. If the spray solution is allowed to settle for one hour or more, re-agitate the spray solution for a minimum of 15 minutes before 
application.

8 
 
Equipment Cleanup Procedures 
1. Drain the tank completely, and then wash out tank , boom and hoses with clean water. Drain again. 
2. Half fill the tank with clean water and add ammonia (i.e., 3% domestic ammonia solution) at a dilution rate of 1% (i.e., 1 gallon 
of domestic ammonia for every 100 gallons of rinsate). Complete filling of the tank with water. Agitate/recirculate and flush 
through boom and hoses. Leave agitation on for 10 minutes. Drain tank completely. 
3. Repeat step 2. 
4. Remove nozzles and screens and soak them in a 1% ammonia solution. Inspect nozzles and screens and remove visible 
residues. 
5. Flush tank, boom, and hoses with clean water. 
6. Inspect tank for visible residues. If present, repeat step 2. 
 
ROTATIONAL CROP RESTRICTIONS 
If a crop is not specified in the following table, conduct a field bioassay as described in the FIELD BIOASSAY section. 
 
 
Crop Rotational Interval 
Wheat 3 Months 
 Triticale 
Soybean 
Rice Bioassay and no less than 3 
months 
Cotton Bioassay and no less than 4 
months Peanuts 
Barley 9 Months 
 
 
 
 
Sunflower 
 Dry Beans 
Lentils 
Chickpea 
Peas 
Corn 
Sorghum 
Sugar Beets 10 Months 
 
 
 
Alfalfa 
Flax 
Mustard 
Canary seed 
Oats, Spring 
Safflower 
Timothy 
Canola 
Leafy Vegetables Bioassay and no less than 10 
months 
Potatoes 18 Months 
All Other Crops Bioassay 
 
 
Field Bioassay / Small Scale Bioassay 
A field bioassay must be completed before rotating to a crop other than those specified in the “Rotational Crop Restrictions” section of 
this label. To conduct an effective field bioassay, grow strips of the crop(s) you intend to grow the following season in a field previously 
treated with Osprey Xtra Herbicide. The test strips should be placed in a controlled area and should include low areas and knolls, and

9 
 
include variations in soil such as type and pH. Crop response to the bioassay will determine if the crop(s) grown in the test strips can be 
grown safely in the areas previously treated with Osprey Xtra Herbicide. 
 
WEEDS CONTROLLED & SUPPRESSED 
OSPREY Xtra Herbicide is a post-emergent herbicide with best results being obtained when applications are made to young actively 
growing weeds. See weed tables for appropriate application timing and weed size. Treat heavy weed infestations before they become 
competitive with the crop. 
 
Rate Tables for Weed Control & Suppression 
Apply OSPREY Xtra Herbicide at a rate of 4.75 ounces per acre in fall sown or winter wheat or fall sown triticale. Weed control at 
selected weed heights and stages is shown in the following tables. 
 
GRASS WEEDS 
Controlled Suppressed 
Common Name 
(Genus/Species) 
Growth Stage/Height 
Common Name 
(Genus/Species) 
Growth Stage/Height 
4.75 oz/Acre 
OSPREY Xtra 
Herbicide 
4.75 oz/Acre 
OSPREY Xtra 
Herbicide 
Blackgrass 
(Alopecurus myosuroides) 1-leaf to 2-tiller Bluegrass, bulbous 
(Poa bulbosa) 1-leaf to prior to boot-stage 
Bluegrass, annual 
(Poa annua) 1-leaf to 2-tiller Brome, soft 
(Bromus hordeaceus) 1-leaf to 2-tiller 
Bluegrass, roughstalk 
(Poa trivialis) 1-leaf to 2-tiller Brome, ripgut 
(Bromus rigidus) 1-leaf to 2-tiller 
Bluegrass, Kentucky 
(Poa pratensis) 1-leaf to 2-tiller Brome, downy 
(Bromus tectorum) 1-leaf to 2-tiller 
Canarygrass, hood,* 
(Phalaris paradoxa) 1-leaf to 2-tiller Brome, Japanese 
(Bromus japonicus) 1-leaf to 2-tiller 
Canarygrass, littleseed,* 
(Phalaris minor) 1-leaf to 2-tiller Cheat 
(Bromus secalinus) 1-leaf to 2-tiller 
Darnel, Persian,* 
(Lolium persicum) 1-leaf to 2-tiller Hairy chess 
(Bromus commutatus) 1-leaf to 2-tiller 
Ryegrass, annual/Italian, 
(Lolium multiflorum) 
1-leaf to 2-tiller Fescue, Rattail 
(Vulpia myuros) 1-leaf to 2-tiller 
Wild oat,* 
(Avena fatua) 1-leaf to 2-tiller Goatgrass, jointed 
(Aegilops cylindrica) 1-leaf to 2-tiller 
Windgrass,* 
(Apera spica-venti 
& Apera interrupta) 
Up to 3 inches Quackgrass 
(Elytrigia repens) 1-leaf to 2-tiller 
 Ventenata 
(Ventenata dubia) 1-leaf to 2-tiller 
*For fields with infestations of wild oat, windgrass, Persian 
darnel, or canarygrass only, 3.2 oz/A of OSPREY Xtra 
Herbicide may be used. 
Suppressed weeds will be stunted in growth and/or be 
reduced in number as compared to non-treated areas but 
performance may not be commercially acceptable.

10 
 
 
 
BROADLEAF WEEDS 
Controlled Suppressed 
Common Name 
(Genus/Species) 
Height 
Common Name 
(Genus/Species) 
Height 
4.75 oz/Acre 
OSPREY Xtra 
Herbicide 
4.75 oz/Acre 
OSPREY Xtra 
Herbicide 
Mustard, tumble 
(Sisymbrium altissimum) 1 - 4 inches Chickweed, common 
(Stellaria media) 1 - 2 inches 
Mustard, wild 
(Brassica kaber) 1 - 2 inches Henbit 
(Lamium amplexicaule) 1 - 2 inches 
Pennycress, field 
(Thlaspi arvense) 1 - 4 inches Pigweed, redroot 
(Amaranthus retroflexus) 1 - 2 inches 
Radish, wild 
(Raphanus raphanistrum) 1 - 2 inches 
Suppressed weeds will be stunted in growth and/or be 
reduced in number as compared to non-treated areas but 
performance may not be commercially acceptable. 
Volunteer Canola 
(Brassica napus 
& Brassica rapa) 
1 - 2 inches 
 
 
SPECIFIC USE DIRECTIONS 
 
 
FALL-SOWN OR WINTER WHEAT & FALL-SOWN TRITICALE 
 
Application Rate and Timing 
Apply OSPREY Xtra Herbicide to fall-sown or winter wheat or fall-sown triticale from emergence up to the jointing stage of growth. 
 
Specific Regional Directions: 
x In California, apply OSPREY Xtra Herbicide fr om emergence to 2-tiller wheat (Feekes 5). 
x In Idaho, Oregon, Washington, and Mont ana, OSPREY Xtra Herbicide may be applied from emergence up to the 2-node stage 
of wheat and fall sown triticale. 
 
Tank Mix Recommendations 
x OSPREY Xtra Herbicide may be tank mixed with the herbicides listed below to provide broad-spectrum weed control. 
x When using OSPREY Xtra Herbicide in tank mix combinations, follow the precautions and directions of the most restrictive 
label. 
x OSPREY Xtra Herbicide contains 0.091 pounds of mefenpyr-diethyl per pound of product. 
x Applying the maximum-labeled rate of OSPREY Xtra Herbicide delivers 0.027 lbs of mefenpyr-diethyl per acre. 
x It is recommended that herbicides not specifically listed on this label for tank mixing with OSPREY Xtra Herbicide be applied 
sequentially, 5 days prior to or 5 days after an OSPREY Xtra Herbicide treatment. 
x Abnormally large temperature fluctuations between daytime highs and nighttime lows at the time of application may influence 
crop tolerance. Frost occurrence the night before or within two days after application may increase crop response. These 
effects can be quite marked when OSPREY Xtra Herbicide is tank mixed with EC (Emulsifiable Concentrate) partners. Consult 
with your Bayer CropScience representative for further guidance concerning tank mixes under these conditions. 
x In Washington, Oregon and Idaho: When tank mixing OSPREY Xtra Herbicide with an EC broadleaf herbicide, reduce the NIS 
rate from 0.5% to 0.25%. 
x Refer to the appropriate label of each tank mix partner for in structions regarding application rates required to control weeds not 
listed on this label. 
 
It is the pesticide user’s responsibility to ensure that all products are registered for the intended use. Read and follow the applicable 
restrictions and limitations and directions for use on all product labels involved in tank mixing. Users must follow the most restrictive 
directions for use and precautionary statements of each product in the tank mixture.

11 
 
Possible Tank Mix Partners for Additional Weed Control 
AffinityTM/Affinity Broadspec Express® Olympus 
Ally®/Ally® EXtra Herbicide Finesse Peak® 
Amber® Harmony®/Harmony® EXtra Herbicide XP Starane™/Starane NXT/Starane Flex 
Buctril® Herbicide1 Huskie® Stinger™ 
Bronate Advanced® Herbicide1 MCP ester/MCP amine2 WideMatch 
Curtail M3 Sentrallas™ 
 
Consult appropriate label of each tank mix partner for exact application rates required to control weeds not listed on this label. 
Tank mixes must be used in accordance with the most restrictive label limitations and precautions. 
1 Equivalent bromoxynil products may be substituted in a tank mix for these products. 
2 Various formulations of MCP Ester/Amine may be tank mixed at manufacturers labeled rates. 
Follow label restrictions for MCPA application and wheat stage of growth. Increased crop response or reduced grass control may occur 
when adding MCP amine to OSPREY Xtra Herbicide. 
3 Curtail M may be tank mixed at manufacturers labels rates. 
 
Tank Mixtures for Disease Control 
OSPREY Xtra Herbicide may be applied in combination with Stratego®, Tilt®, Priaxor™, Trivapro®, or Topsin® M 70WP fungicides for 
weed and disease control. Refer to the specific fungicide label for use directions, application rates, restrictions and a list of diseases 
controlled. 
 
Tank Mixtures for Insect Control 
OSPREY Xtra Herbicide may be applied with Baythroid XL, Warrior® Insecticide with Zeon Technology or Z-Cype 0.8 EC Insecticide. 
Refer to the specific insecticide label for use directions, application rates, restrictions and a list of insects controlled. 
 
Tank Mix Precautions 
Always follow the label instructions of the tank mix partner as well as OSPREY Xtra Herbicide. Check the compatibility of OSPREY Xtra 
Herbicide and the tank mix partner by mixing all components in the order specified in the Order of Mixing section, including adjuvants 
and water, into a small separate container in order to evaluate compatibility prior to adding them to the tank. 
 
Spray Additives 
OSPREY Xtra Herbicide is a water dispersible granule that does not include an adjuvant. A recommended adjuvant must be tank mixed 
with OSPREY Xtra Herbicide according to the guidelines as described in the Order of Mixing section. 
 
Do not use additives that alter the spray solution below 6.0 pH. Best results are obtained at spray solution pH of 6.0 – 8.0. 
 
Organosilicone-based surfactants or crop oil concentrate surfactants are not recommended for use with OSPREY Xtra Herbicide. 
 
Non-ionic Surfactant (NIS) + Ammonium Nitrogen Fertilizer (in water carrier solutions) 
Use a non-ionic surfactant at a concentration of 0.5% v/v (2 qt per 100 gallons of spray solution) with ammonium nitrogen fertilizer. At 
least 80% of the surfactant product must be active non-ionic surfactant. Avoid products that do not accurately define their ingredients. 
Products must contain only EPA-exempt ingredients (40 CFR 1001). 
 
Use a spray grade quality urea ammonium nitrogen fertilizer (20-0-0 to 32-0-0 at 1 – 2 qt/acre) or ammonium sulfate fertilizer (21-0-0-24 
at 1.5 – 3 lbs/acre). 
 
Fluid Fertilizer Carrier Solution Applications 
OSPREY Xtra Herbicide provides consistent performance when applied with water as the spray carrier and a non-ionic surfactant is 
added to the spray solution. However, OSPREY Xtra Herbicide may be applied using a liquid nitrogen solution (28-0-0 or 30-0-0 or 32-0-
0) as the spray carrier. The fertilizer spray solution should not exceed 15% liquid nitrogen (1.5 gallons of liquid nitrogen in 10 gallons of 
spray solution per acre). A non-ionic surfactant at a maximum concentration of 0.25% v/v (1 quart per 100 gallons of spray solution) is 
required in spray solutions containing liquid nitrogen carrier. 
 
Due to the activity of fertilizer on the crop, temporary injury may result when liquid nitrogen is used as a spray carrier. Crop response 
symptoms due to the use of liquid nitrogen as a spray carrier may include discoloration, and leaf burn. 
 
Fluid Fertilizer Carrier Solution Applications: Washington, Oregon and Idaho Only 
Apply OSPREY Xtra Herbicide by ground only from emergence up to the second node of crop development in spray solutions containing 
liquid nitrogen carrier. 
 
Use 3.2 – 4.75 ounces OSPREY Xtra Herbicide /acre by ground in tank mixture with 0.25% v/v non-ionic surfactant up to 3 gallons of 
liquid nitrogen (20-0-0 to 32-0-0) in a minimum 10-gallon mix per acre.

12 
 
STORAGE AND DISPOSAL 
Do not contaminate water, food, or feed by storage or disposal. 
 
Pesticide storage 
Store in a cool, dry place. 
 
Pesticide disposal 
Wastes resulting from the use of this product must be disposed of on site or at an approved waste disposal facility. 
 
Container handling 
 
[Non-Seed Treatment Products in Non-Refillable Containers] 
 
Rigid, Non-refillable containers (equal to or less than 5 gallons) 
Non-refillable container. Do not reuse or refill this container. Offer for recycling, if available. Triple rinse or pressure rinse container (or 
equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank 
and drain for 10 seconds after the flow begins to drip. Fill the container 1/4 full with water and recap. Shake for 10 seconds. Pour 
rinsate into application equipment or a mix tank or store rinsate for later use or disposal. Drain for 10 seconds after the flow begins to 
drip. Repeat this procedure two more times. 
 
Pressure rinse as follows: Empty the remaining contents into application equipment or a mix tank and continue to drain for 10 
seconds after the flow begins to drip. Hold container upside down over application equipment or mix tank or collect rinsate for later 
use or disposal. Insert pressure rinsing nozzle in the side of the container, and rinse at about 40 PSI for at least 30 seconds. Drain for 
10 seconds after the flow begins to drip. 
 
Once container is rinsed, offer for recycling if available or puncture and dispose of in a sanitary landfill. 
 
[OR] 
 
Rigid Non-refillable Containers that are too large to shake (i.e., with capacities greater than 5 gallons or 50 lbs) 
Non-refillable container. Do not reuse or refill this container. Refer to Bottom Discharge IBC or Top Discharge IBC, Drums, Kegs 
information as follows. 
 
Bottom Discharge IBC (e.g. – Schuetz Caged IBC or Snyder Square Stackable) 
Pressure rinsing the container before final disposal is the responsibility of the person disposing of the container. To pressure rinse the 
container before final disposal, empty the remaining contents from the IBC into application equipment or mix tank. Raise the bottom of 
the IBC by 1.5 inches on the side which is opposite of the bottom discharge valve to promote more complete product removal. 
Completely remove the top lid of the IBC. Use water pressurized to at least 40 PSI to rinse all interior portions. Continuously pump or 
drain rinsate into application equipment or rinsate collection system while pressure rinsing. Continue pressure rinsing for 2 minutes or 
until rinsate becomes clear. Replace the lid and close bottom valve. 
 
Top Discharge IBC, Drums, Kegs (e.g.– Snyder 120 Next Gen, Bonar B120, Drums, Kegs) 
Triple rinsing the container before final disposal is the responsibility of the person disposing of the container. To triple rinse the 
container before final disposal, empty the remaining contents from this container into application equipment or mix tank. Fill the 
container at least 10 percent full with water. Agitate vigorously or recirculate water with the pump for 2 minutes. Rinse all interior 
surfaces. Pour or pump rinsate into application equipment or rinsate collection system. Repeat this procedure two more times. 
 
Once container is rinsed, offer for recycling if available or puncture and dispose of in a sanitary landfill or by incineration. 
 
Non-Seed Treatment Products in Non-Refillable Fiber Drums with Liners 
Non-refillable container. Do not reuse or refill this container. Completely empty liner by shaking and tapping sides and bottom to 
loosen clinging particles. Empty residue into application equipment, then offer for recycling if available or dispose of in a sanitary 
landfill or by incineration. If drum is contaminated and cannot be reused, dispose of it in the manner required for its liner. 
 
Non-Seed Treatment Products in Non-Rigid, Non-refillable Containers 
Non-refillable container. Do not reuse or refill this container. Completely empty container into application equipment. Then offer for 
recycling if available or dispose of in a sanitary landfill or by other procedures approved by state and local authorities. 
 
[OR] 
 
[Non-Seed Treatment Products in Refillable Containers] 
 
Refillable container. Refer to Bottom Discharge IBC or Top Discharge IBC, Drums, Kegs information as follows. Refill this container 
with pesticide only. Do not reuse this container for any other purpose. Contact your Ag retailer or Bayer CropScience for container 
return, disposal and recycling information.

13 
 
 
Bottom Discharge IBC (e.g. – Schuetz Caged IBC or Snyder Square Stackable) 
Pressure rinsing the container before final disposal is the responsibility of the person disposing of the container. Cleaning before 
refilling is the responsibility of the refiller. To pressure rinse the container before final disposal, empty the remaining contents from the 
IBC into application equipment or mix tank. Raise the bottom of the IBC by 1.5 inches on the side which is opposite of the bottom 
discharge valve to promote more complete product removal. Completely remove the top lid of the IBC. Use water pressurized to at 
least 40 PSI to rinse all interior portions. Continuously pump or drain rinsate into application equipment or rinsate collection system 
while pressure rinsing. Continue pressure rinsing for 2 minutes or until rinsate becomes clear. Replace the lid and close bottom valve. 
 
Top Discharge IBC, Drums, Kegs (e.g.
– Snyder 120 Next Gen, Bonar B120, Drums, Kegs) 
Triple rinsing the container before final disposal is the responsibility of the person disposing of the container. Cleaning before refilling 
is the responsibility of the refiller. To triple rinse the containers before final disposal, empty the remaining contents from this container 
into application equipment or mix tank. Fill the container at least 10 percent full with water. Agitate vigorously or recirculate water with 
the pump for 2 minutes. Rinse all interior surfaces. Pour or pump rinsate into application equipment or rinsate collection system. 
Repeat this procedure two more times. 
 
Once container is rinsed, offer for recycling if available or puncture and dispose of in a sanitary landfill or by incineration. 
 
End users are authorized to remove tamper evident cables as required to remove the product from the container unless the container 
is equipped with one way valves and refilling or returning is planned. If this is the case, end users are not authorized to remove 
tamper evident cables, one way valves or clean container. 
 
 
CONDITIONS OF SALE AND LIMITATIONS OF WARRANTY AND LIABILITY 
Read the entire Directions for Use, Conditions, Disclaimer of Warranties and Limitations of Liability before using this product. If terms are 
not acceptable, return the unopened product container at once. 
By using this product, user or buyer accepts the following Conditions, Disclaimer of Warranties and Limitations of Liability. 
CONDITIONS: The directions for use of this product are believed to be adequate and must be followed carefully. However, it is impossible 
to eliminate all risks associated with the use of this product. Crop injury, ineffectiveness or other unintended consequences may result 
because of such factors as weather conditions, presence of other materials, or the manner of use or application, all of which are beyond 
the control of Bayer CropScience. To the extent consistent with applicable law, all such risks shall be assumed by the user or buyer. 
DISCLAIMER OF WARRANTIES: 
TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER CROPSCIENCE MAKES 
NO OTHER WARRANTIES, EXPRESS OR IMPLIED, OF MERCHA NTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE OR 
OTHERWISE, THAT EXTEND BEYOND THE STATEMENTS MADE ON THIS LABEL. No agent of Bayer CropScience is authorized to 
make any warranties beyond those contained herein or to modify the warranties contained herein. TO THE EXTENT CONSISTENT 
WITH APPLICABLE LAW, B AYER CROPSCIENCE DISCLAIMS ANY LIABILITY WHATSOEVER FOR SPECIAL, INCIDENTAL OR 
CONSEQUENTIAL DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT. 
LIMITATIONS OF LIABILITY: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE USER 
OR BUYER FOR ANY AND ALL LOSSES, INJURIES OR DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS 
PRODUCT, WHETHER IN CONTRACT, WARRANTY, TORT, NEGLIGENCE, STRICT LIABILITY OR OTHERWISE, SHALL NOT 
EXCEED THE PURCHASE PRICE PAID, OR AT BAYER CROP SCIENCE’S ELECTION, THE REPLACEMENT OF PRODUCT. 
Baythroid XL, Bronate Advanced, Buctril, Huskie, Olympus, Stratego and Varro are registered trademarks of Bayer. 
Affinity, Ally, Ally EXtra Herbicide, Finesse, Express, Harmony EXtra Herbicide, Harmony, and Sentrallas are registered 
trademarks of E.I. DuPont de Nemours Company. 
Topsin is a registered trademark of Cerexagri, Inc. 
Curtail is a registered trademark of Dow AgroSciences LLC. Starane, Starane Flex, Starane NXT, Stinger, and Widematch 
are trademarks of Dow AgroSciences LLC. 
Amber, Tilt, Warrior, Peak, and Trivapro are registered trademarks of Syngenta Crop Protection, Inc. 
Priaxor is a registered trademark of BASF Corporation. 
 
Osprey is a registered trademark of Bayer Group. 
 
 
OSPREY Xtra Herbicide (PENDING) 10/19/2020, 02/25/2021, 02/26/2021, 3/22/2021, 03/30/2021, 04/07/2021, 
01/16/2024, 09/13/2024, 09/27/2024, 10/11/2024, 10/16/2024, 10/18/2024