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554 lines
25 KiB
Markdown
# APRONMAXX RFC
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- EPA Reg No: **100-1195**
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- Registrant: SYNGENTA CROP PROTECTION, LLC
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- Signal word: Caution
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- Active ingredients: Fludioxonil (2.31%); Metalaxyl-M (3.46%)
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- Label accepted: 2026-06-24
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- Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000100-01195-20260624.pdf
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---
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June 24, 2026
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Matthew Flanery
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Regulatory Product Manger
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Syngenta Crop Protection, LLC
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P.O. Box 18300
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Greensboro, NC 27419
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Subject: Label Amendment - Registrati on Review Mitigation for Metalaxyl - M
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Product Name: APRONMAXX RFC
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EP A Registration Number: 100-1195
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Case Number: 482305
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Application Dates: November 20, 2020
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Dear Matthew Flanery:
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The Agency, in accordance with the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA),
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as amended, has completed reviewing all the information submitted with your application to
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support the Registration Review of the above referenced product in connection with the
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Metalaxyl - M Decision, and has concluded that your submission is acceptable. The label
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referred to above, submitted in connection with registration under FIFRA, as amended, is
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acceptable.
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Should you wish to add/retain a reference to the company’s website on your label, then please
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be aware that the website becomes labeling under the Federal Insecticide, Fungicide, and
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Rodenticide Act and is subject to review by the Agency. If the website is false or misleading, the
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product would be misbranded and unlawful to sell or distribute under FIFRA section 12(a)(1)(E).
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40 CFR 156.10(a)(5) list examples of statements EPA may consider false or misleading. In
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addition, regardless of whether a website is referenced on your product’s label, claims made on
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the website may not substantially differ from those claims approved through the registration
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process. Therefore, should the Agency find or if it is brought to our attention that a website
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contains false or misleading statements or claims substantially differing from the EPA approved
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registration, the website will be referred to the EPA’s Office of Enforcement and Compliance
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Assurance.
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A stamped copy of your labeling is enclosed for your records. This labeling supersedes
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all previously accepted labeling and must be used at your next label printing. You must
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submit one copy of the final printed labeling before you release the product for
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Page 2 of 2
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EPA Reg. No. 100-1195
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Case No. 482305
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shipment with the new labeling. In accordance with 40 CFR 152.130(c), you may
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distribute or sell this product under the previously approved labeling for 12 months
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from the date of this letter. After 12 months, you may only distribute or sell this
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product if it bears this new revised labeling or subsequently approved labeling. “To
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distribute or sell” is defined under FIFRA section 2(gg) and its implementing regulation
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at 40 CFR 152.3.
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If you have any questions about this letter, please contact Nick Barnett by phone at 513-276-
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6528, or via email at Barnett.nicholas@epa.gov.
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S i n c e r e l y ,
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Julie Javier, Team Leader
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Risk Mitigation and Implementation Branch 4
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Pesticide Re-Evaluation Division
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Office of Pesticide Programs
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ENCLOSURE: Stamped label
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MEFENOXAM GROUP 4 FUNGICIDE
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FLUDIOXONIL GROUP 12 FUNGICIDE
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ApronMAXX® RFC
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Fungicide
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Broad-spectrum seed treatment fungicide for protection against seed and seed-borne
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diseases.
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Active Ingredients:
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Fludioxonil*:............................................................................................................ 2.31%
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Mefenoxam**:......................................................................................................... 3.46%
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Other Ingredients: 94.23%
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Total: 100.00%
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*CAS No. 131341-86-1
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**CAS Nos. 70630-17-0 and 69516-34-3
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Contains 0.21 pound active ingredient of fludioxonil and 0.31 pound active ingredient of
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mefenoxam per gallon.
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KEEP OUT OF REACH OF CHILDREN.
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CAUTION
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See additional precautionary statements and directions for use inside booklet.
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EPA Reg. No. 100-1195
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________gallons
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Net Contents
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Jun 24, 2026
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100-1195
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-2-
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FIRST AID
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If on skin or
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clothing
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x Take off contaminated clothing.
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x Rinse skin immediately with plenty of water for 15-20 minutes.
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x Call a poison control center or doctor for treatment advice.
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Have the product container or label with you when calling a poison control center or
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doctor, or going for treatment.
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HOTLINE NUMBER
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For 24 Hour Medical Emergency Assistance (Human or Animal) or
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Chemical Emergency Assistance (Spill, Leak, Fire, or Accident),
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Call
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1-800-888-8372
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PRECAUTIONARY STATEMENTS
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Hazards to Humans and Domestic Animals
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CAUTION
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Harmful if absorbed through the skin. Avoid contact with skin, eyes, or clothing. Wash
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thoroughly with soap and water after handling. Prolonged or frequently repeated skin
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contact may cause allergic reactions in some individuals.
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Personal Protective Equipment (PPE)
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Applicators and other handlers must wear:
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x Long-sleeved shirt and long pants
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x Chemical-resistant gloves made of barrier laminate, butyl rubber 14 mils, nitrile
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rubber 14 mils, neoprene rubber 14 mils, or polyvinyl chloride (PVC) 14 mils or
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Viton™ 14 mils
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x Shoes plus socks
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Follow manufacturer’s instructions for cleaning/maintaining PPE. If no such instructions
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for washables exist, use detergent and hot water. Keep and wash PPE separately from
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other laundry.
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-3-
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Engineering Control Statements
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When handlers use closed systems in a manner that meets the requirements listed in
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the Worker Protection Standard (WPS) for agricultural pesticides (40 CFR 170.607 (d)
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and (e)), the handler PPE requirements may be reduced or modified as specified in the
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WPS.
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User Safety Recommendations
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Users should:
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x Wash hands before eating, drinking, chewing gum, using tobacco, or using the toilet.
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x Remove clothing/PPE immediately if pesticide gets inside. Then wash thoroughly
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and put on clean clothing.
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x Remove PPE immediately after handling this product. Wash the outside of gloves
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before removing. As soon as possible, wash thoroughly and change into clean
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clothing.
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Environmental Hazards
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This pesticide is toxic to freshwater and estuarine/marine fish and aquatic invertebrates.
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Do not contaminate water when disposing of equipment washwater or rinsate.
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Groundwater Advisory Statement
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Mefenoxam is known to leach through soil into groundwater under certain conditions as
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a result of agricultural use. Use of this chemical in areas where soils are permeable,
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particularly where the water table is shallow, may result in groundwater contamination.
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-4-
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CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY
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NOTICE: Read the entire Directions for Use and Conditions of Sale and Limitation of
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Warranty and Liability before buying or using this product. If the terms are not
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acceptable, return the product at once, unopened, and the purchase price will be
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refunded.
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The Directions for Use of this product must be followed carefully. It is impossible to
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eliminate all risks inherently associated with the use of this product. Crop injury,
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ineffectiveness or other unintended consequences may result because of such factors
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as manner of use or application, weather or crop conditions, presence of other materials
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or other influencing factors in the use of the product, which are beyond the control of
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SYNGENTA CROP PROTECTION, LLC or Seller. To the extent consistent with
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applicable law, Buyer and User agree to hold Syngenta and Seller harmless for any
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claims relating to such factors.
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SYNGENTA warrants that this product conforms to the chemical description on the label
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and is reasonably fit for the purposes stated in the Directions for Use, subject to the
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inherent risks referred to above, when used in accordance with directions under normal
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use conditions. To the extent consistent with applicable law: (1) this warranty does not
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extend to the use of the product contrary to label instructions or under conditions not
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reasonably foreseeable to or beyond the control of Seller or SYNGENTA, and (2) Buyer
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and User assume the risk of any such use. TO THE EXTENT CONSISTENT WITH
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APPLICABLE LAW, SYNGENTA MAKES NO WARRANTIES OF MERCHANTABILITY
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OR OF FITNESS FOR A PARTICULAR PURPOSE NOR ANY OTHER EXPRESS OR
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IMPLIED WARRANTY EXCEPT AS WARRANTED BY THIS LABEL.
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To the extent consistent with applicable law, in no event shall SYNGENTA be liable for
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any incidental, consequential or special damages resulting from the use or handling of
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this product. TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, THE
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EXCLUSIVE REMEDY OF THE USER OR BUYER, AND THE EXCLUSIVE LIABILITY
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OF SYNGENTA AND SELLER FOR ANY AND ALL CLAIMS, LOSSES, INJURIES
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OR DAMAGES (INCLUDING CLAIMS BASED ON BREACH OF WARRANTY,
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CONTRACT, NEGLIGENCE, TORT, STRICT LIABILITY OR OTHERWISE)
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RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, SHALL BE THE
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RETURN OF THE PURCHASE PRICE OF THE PRODUCT OR, AT THE ELECTION
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OF SYNGENTA OR SELLER, THE REPLACEMENT OF THE PRODUCT.
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SYNGENTA and Seller offer this product, and Buyer and User accept it, subject to the
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foregoing conditions of Sale and Limitation of Warranty and Liability, which may not be
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modified except by written agreement signed by a duly authorized representative of
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SYNGENTA.
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-5-
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DIRECTIONS FOR USE
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It is a violation of federal law to use this product in a manner inconsistent with its
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labeling.
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Do not apply this product in a way that will contact workers or other persons, either
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directly or through drift. Only protected handlers may be in the area during application.
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For any requirements specific to your State or Tribe, consult the agency responsible for
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pesticide regulation.
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Treatment of highly mechanically damaged seed, or seed of known low vigor and poor
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quality, may result in reduced germination and/or reduction of seed and seedling vigor.
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Treat and conduct germination test on a small portion of seed before committing the
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total seed lot to a selected chemical treatment. Due to seed-quality conditions beyond
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the control of Syngenta crop protection, no claims are made to guarantee germination of
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carry-over seed.
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Maximum usage when applying metalaxyl- and mefenoxam- containing products
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to the same crop within the same season: Do not apply more than the maximum
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yearly total application rate for the active ingredient as stated on the label of the product
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containing the lowest yearly total on that crop.
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AGRICULTURAL USE REQUIREMENTS
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Use this product only in accordance with its labeling and with the Worker Protection
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Standard, 40 CFR part 170. This Standard contains requirements for the protection of
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agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of
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agricultural pesticides. It contains requirements for training, decontamination, and
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emergency assistance. It also contains specific instructions and exceptions pertaining
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to the statements on this label about personal protective equipment (PPE) and
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restricted-entry interval. The requirements in this box only apply to uses of this product
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that are covered by the Worker Protection Standard.
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Do not enter or allow worker entry into treated areas during the restricted-entry
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interval (REI) of 48 hours. Exception: If the seed is treated with the product and the
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treated seed is soil-injected or soil-incorporated, the Worker Protection Standard, under
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certain circumstances, allows workers to enter the treated area if there will be no
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contact with anything that has been treated.
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PPE required for early entry to treated areas that is permitted under the Worker
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Protection Standard and that involves contact with anything that has been treated, such
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as plants, soil, or water is:
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x Coveralls
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x Chemical-resistant
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gloves made of barrier laminate, butyl rubber > 14 mils, nitrile
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-6-
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rubber > 14 mils, neoprene rubber > 14 mils, or polyvinyl chloride (PVC) > 14
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mils or Viton > 14 mils
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x Shoes plus socks
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FAILURE TO FOLLOW THE DIRECTIONS FOR USE AND PRECAUTIONS ON THIS
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LABEL MAY RESULT IN CROP INJURY, POOR DISEASE CONTROL, OR ILLEGAL
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RESIDUES.
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GENERAL INFORMATION
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ApronMAXX RFC is a seed treatment fungicide that protects against damping-off and
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seed rots due to Pythium, Phytophthora, Fusarium, Rhizoctonia spp., and early season
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Phytophthora root rot. ApronMAXX RFC also suppresses seed-borne Sclerotinia and
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Phomopsis spp., particularly in soybeans. ApronMAXX RFC contains the active
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ingredient mefenoxam found in Apron XL
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® that provides protection against Pythium and
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early season Phytophthora root rot. ApronMAXX RFC also contains the active
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ingredient fludioxonil found in Maxim
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® 4FS and Maxim 480FS that provides protection
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against the remaining diseases mentioned in this label.
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Resistance Management Recommendations
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MEFENOXAM GROUP 4 FUNGICIDE
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FLUDIOXONIL GROUP 12 FUNGICIDE
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For resistance management, please note that Apron MAXX RFC contains Group 4/
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mefenoxam and Group 12/fludioxonil fungicides. Any fungal population may contain
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individuals naturally resistant to Apron MAXX RFC and other Group 4 or Group 12
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fungicides. A gradual or total loss of pest control may occur over time if these fungicides
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are used repeatedly in the same fields. Appropriate resistance-management strategies
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should be followed.
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Mefenoxam belongs to the phenylamide class of chemistry which interferes with fungal
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RNA synthesis. Fludioxonil belongs to the phenylpyrrole class of chemistry which
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interferes with osmotic signal transduction.
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To delay fungicide resistance, take one or more of the following steps:
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x Rotate the use of Apron MAXX RFC or other Group 4 or Group 12 fungicides within
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a growing season sequence with different groups that control the same pathogens.
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x Use tank mixtures with fungicide from a different group that are equally effective on
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the target pest when such use is permitted. Use at least the minimum application
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rate as labeled by the manufacturer.
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x Adopt an integrated disease management program for fungicide use that includes
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scouting, uses historical information related to pesticide use, and crop rotation, and
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which considers host plant resistance, impact of environmental conditions on
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disease development, disease thresholds, as well as cultural, biological and other
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chemical control practices.
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-7-
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x Where possible, make use of predictive disease models to effectively time fungicide
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applications. Note that using predictive models alone is not sufficient to manage
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resistance.
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x Monitor treated fungal populations for resistance development.
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x Contact your local extension specialist or certified crop advisor for any additional
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pesticide resistance-management and/or IPM recommendations for specific crop
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and pathogens.
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x For further information or to report suspected resistance contact Syngenta at 1-866-
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Syngent(a) (866-796-4368). You can also contact your pesticide distributor or
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university extension specialist to report resistance.
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Make all applications according to the use directions that follow. If a rate range is
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specified, use higher rates of ApronMAXX RFC when the disease pressure is expected
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to be high.
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MIXING INSTRUCTIONS FOR SOYBEANS
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ApronMAXX RFC is especially formulated for on-farm or commercial treatment to be
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used with liquid rhizobia products, using standard mechanical slurry or mist-type seed
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treatment equipment which accurately measures and mixes a flowable seed treatment.
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The equipment must provide uniform coverage of ApronMAXX RFC on the seed.
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Uneven seed coverage may not give the desired level of disease control. ApronMAXX
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RFC must be diluted with either water or liquid inoculants prior to application to
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soybeans. Consult the manufacturer of the application equipment you plan to use for
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suitability for this application and for instructions on operation and calibration of the
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equipment. Do not mix ApronMAXX RFC fungicide with other pesticides unless
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sufficient compatibility, loading rates, and seed and crop safety factors are determined.
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Do not mix with any product that contains a prohibition on mixing. Follow the more
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restrictive labeling of any tank-mix partner.
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In a clean container large enough to contain the entire mixture add the desired amount
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of ApronMAXX RFC. Add half of the required water or liquid inoculant and mix
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thoroughly. Add the remaining amount of water or liquid inoculant and mix again. The
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slurry is ready for application to the soybeans. Mix as needed and do not store diluted
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mixture.
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Additional or continuous agitation or mixing of the slurry mixture may be necessary to
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prevent the ApronMAXX RFC from settling out of solution when using water or liquid
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inoculants.
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ApronMAXX RFC has been found to be compatible with some liquid inoculant products.
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ApronMAXX RFC may be mixed or applied sequentially with approved liquid inoculants.
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Consult the maker of the liquid inoculants and a Syngenta Crop Protection
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representative for directions before applying ApronMAXX RFC with liquid inoculants.
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-8-
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Special Precaution: ApronMAXX RFC is specially formulated to be compatible with
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some liquid inoculants. If water is used to further dilute ApronMAXX RFC when
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rhizobia are present, use only nonchlorinated water. Chlorinated water will kill
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the live rhizobia contained in the inoculant.
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MIXING INSTRUCTIONS FOR OTHER LEGUMES
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Apply ApronMAXX RFC as a water-based slurry utilizing standard slurry seed treatment
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equipment which provides uniform seed coverage. Uneven or incomplete seed
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coverage may not give the desired level of disease protection. Thoroughly mix the
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labeled amount of ApronMAXX RFC into the required amount of water for the slurry
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treater and dilution rate to be used.
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Follow the manufacturer application instructions for the seed treatment equipment being
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used. Maintain constant agitation of the slurry during the treatment. Allow seed to dry
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before bagging.
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-9-
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CROP USE DIRECTIONS
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ApronMAXX RFC contains an EPA-approved/colorant that imparts an unnatural color to
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the seed as required by the Federal Seed Act.
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SEED BAG TAG LABEL REQUIREMENTS
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Federal law requires that bags of treated seed shall be labeled with the following
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information:
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x This seed has been treated with fludioxonil and mefenoxam fungicides.
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x DO NOT use for food, feed or oil purposes.
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The U.S. Environmental Protection Agency requires that bags containing treated seed
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shall be labeled with the following statements.
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x Store treated seed away from food and feedstuffs.
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x DO NOT allow children, pets, or livestock to have access to treated seed.
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x Wear long-sleeved shirt, long pants, and chemical-resistant gloves when handling
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treated seed.
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x Treated seed exposed on soil surface may be hazardous to wildlife. Cover or
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collect treated seed spilled during loading and planting (such as in row ends).
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x Treated seed must be planted into the soil at a depth greater than 1 inch.
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x DO NOT contaminate water bodies when disposing of planting equipment
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washwater.
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x Dispose of seed packaging in accordance with local requirements.
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x Soybean: This seed has been treated with [0.0037] mg fludioxonil and [0.0055]
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mg mefenoxam per seed. [These values are based on a seed weight of 3,000
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seeds/lb of seed. Calculate the actual values based on the seed weight of the
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seed being treated and how much Apron XL (mefenoxam) is added.] DO NOT
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apply more than 0.052 lb ai/A (23 g ai/A) per calendar year of mefenoxam- or
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metalaxyl-containing products as a seed treatment on Soybean.
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x Legume Vegetables: This seed has been treated with _______ mg fludioxonil
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and _______ mg mefenoxam per seed. [Calculate the actual values based on the
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seed weight of the seed being treated and how much Apron XL (mefenoxam) is
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added.] DO NOT apply more than 0.25 lb ai/A (115 g ai/A) per calendar year of
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mefenoxam- or metalaxyl-containing products as a seed treatment on Legume
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Vegetables.
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Soybean
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ApronMAXX RFC provides protection against damping-off and seed rots due to
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Pythium, Phytophthora, Fusarium, Rhizoctonia spp., and early season Phytophthora
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root rot. ApronMAXX RFC also suppresses seed-borne Sclerotinia and Phomopsis spp.
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For these soybean diseases, apply ApronMAXX RFC at the rate specified in the rate
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table, plus water at 3.5 fl oz per 100 lbs. seed. Alternatively, approved liquid rhizobia
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inoculants at rates specified by manufacturer to achieve proper total slurry volumes can
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be used. If the target fields have a history of high Phytophthora pressure, then use
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Apron XL as specified in the rate table. Read and follow all label directions for Apron
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XL use.
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-10-
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Soybean Use Rate*
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ApronMAXX RFC** Additional Apron XL
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1.5 fl oz/100 lb seed**
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or
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0.005 fl oz/1,000 seed
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or
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0.7 fl oz/140,000 seed
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0.16-0.48 fl oz/100 lb seed
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or
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0.0005-0.0016 fl oz/1,000 seed
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or
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0.075-0.224 fl oz/140,000 seed
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0.0037 mg fludioxonil + 0.0055 mg
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mefenoxam = 0.0092 mg total ai/seed
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0.0057 - 0.017 mg mefenoxam/seed
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*Based on 3,000 seeds per pound.
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**Contains 3.75 g of mefenoxam and 2.5 g of fludioxonil/100 kg of seed.
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Use Restriction When Planting Treated Seeds: DO NOT apply more than 0.052 lb
|
||
ai/A (23 g ai/A) per calendar year of mefenoxam- or metalaxyl-containing products as a
|
||
seed treatment on Soybean.
|
||
|
||
Legume Crops
|
||
Bean (Lupinus spp.)
|
||
(grain lupin, sweet lupin, white lupin, white sweet lupin)
|
||
Bean (Phaseolus spp.)
|
||
(field bean, kidney bean, lima bean, navy bean, pinto bean, runner bean, snap bean,
|
||
tepary bean, wax bean)
|
||
Bean (Vigna spp.)
|
||
(adzuki bean, asparagus bean, black-eyed pea, catjang, Chinese longbean, cowpea,
|
||
Crowder pea, moth bean, mung bean, rice bean, southern pea, urd bean, yardlong
|
||
bean)
|
||
Broad bean (fava bean)
|
||
Chickpea (garbanzo bean)
|
||
Guar
|
||
Jackbean
|
||
Lablab bean (hyacinth bean)
|
||
Lentil
|
||
Pea (Pisum spp.)
|
||
(dwarf pea, edible-pod pea, English pea, field pea, garden pea, green pea, snow
|
||
pea, sugar snap pea)
|
||
Pigeon pea
|
||
Sword bean
|
||
|
||
ApronMAXX RFC provides protection against damping-off and seed rots due to
|
||
Pythium, Phytophthora, Fusarium, Rhizoctonia spp., and early season Phytophthora
|
||
root rot. Additional Apron XL may be necessary depending on the type of pathogen and
|
||
the level of disease pressure. Use the table below to determine the appropriate use
|
||
rate of ApronMAXX RFC and Apron XL, if needed. Read and follow all label directions
|
||
for Apron XL use.
|
||
|
||
-11-
|
||
Use Rate
|
||
(fl oz/100 lbs. seed)
|
||
Pathogens ApronMAXX RFC Apron XL
|
||
Pythium (low pressure), Fusarium and
|
||
Rhizoctonia
|
||
1.5 --
|
||
Pythium (high pressure), Fusarium and
|
||
Rhizoctonia
|
||
1.5 0.16
|
||
Pythium (high pressure), Phytophthora,
|
||
Fusarium and Rhizoctonia
|
||
1.5 0.48
|
||
|
||
Use Restriction When Planting Treated Seeds: DO NOT apply more than 0.25 lb ai/A
|
||
(115 g ai/A) per calendar year of mefenoxam- or metalaxyl-containing products as a
|
||
seed treatment on Legume Vegetables.
|
||
|
||
STORAGE AND DISPOSAL
|
||
|
||
Do not contaminate water, food or feed by storage or disposal. Open dumping is
|
||
prohibited.
|
||
|
||
Pesticide Storage
|
||
|
||
Store in the original container and only in a cool, dry, secure place. Keep container
|
||
closed when not in use. Do not store near food or feed. In case of spill on floor or
|
||
paved surfaces, mop and remove to chemical waste storage area until proper disposal
|
||
can be made if product cannot be used according to the label.
|
||
|
||
Pesticide Disposal
|
||
|
||
Pesticide wastes are acutely hazardous. Improper disposal of excess pesticide, spray
|
||
mixture, or rinsate is a violation of federal law. If these wastes cannot be disposed of by
|
||
use according to label instructions, contact your state pesticide or environmental control
|
||
agency, or the hazardous waste representative of the nearest EPA regional office for
|
||
guidance.
|
||
|
||
Container Handling
|
||
|
||
Non-refillable container. Do not reuse or refill this container. Triple rinse container (or
|
||
equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining
|
||
contents into application equipment or a mix tank. Fill the container ¼ full with water.
|
||
Replace and tighten closures. Tip container on its side and roll it back and forth,
|
||
ensuring at least one complete revolution, for 30 seconds. Stand the container on its
|
||
end and tip it back and forth several times. Turn the container over onto its other end
|
||
and tip it back and forth several times. Empty the rinsate into application equipment or
|
||
a mix tank or store rinsate for later use or disposal. Repeat this procedure two more
|
||
times. Then offer for recycling if available or puncture and dispose of in a sanitary
|
||
|
||
-12-
|
||
landfill, or by incineration, or by other procedures approved by state and local
|
||
authorities.
|
||
|
||
CONTAINER IS NOT SAFE FOR FOOD, FEED OR DRINKING WATER.
|
||
|
||
|
||
ApronMAXX
|
||
® RFC, Maxim®, Apron XL® the ALLIANCE FRAME, the Syngenta Logo and
|
||
the PURPOSE ICON are Trademarks of a Syngenta Group Company
|
||
|
||
Viton™ is a trademark of The Chemours Company FC, LLC
|
||
© 20XX Syngenta
|
||
|
||
|
||
For non-emergency (e.g., current product information), call
|
||
Syngenta Crop Protection at 1-866-796-4368.
|
||
|
||
|
||
Manufactured for:
|
||
Syngenta Crop Protection, LLC
|
||
P.O. Box 18300
|
||
Greensboro, North Carolina 27419-8300
|
||
|
||
|
||
APRON MAXX RFC 1195 MAS 0719 AMEND-D OCT2020-CL – jeb– 05/20/2026
|
||
000100-01195.20201022D.APRON_MAXX_RFC.AMEND-OCT2020-CL.PDF
|