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crop-chem-docs/corpus/epa_ppls/100-1469.md
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Image rebuild (skip scrape) / build (push) Failing after 1h37m12s
docker: production image + Gitea Actions for monthly refresh
Dockerfile: self-contained image with corpus + Chroma + BM25 baked
in. Drawbar's compose pulls + runs without volume mounts. Built from
sources.json (labels schema), PRODUCT_NAME=crop_chem by default,
HYBRID_SEARCH=true (always-on for production quality). RERANK_URL +
OLLAMA_URL get set at compose time.

.gitea/workflows/refresh.yml: monthly cron (1st @ 06:00 UTC) does
full scrape → reindex → image push. Scrapes Bayer (~30 min) +
EPA PPLS row-crop filtered (~7h). Skips reindex+push if no corpus
diff. Tags pushed: :latest, :<sha12>, :corpus-<YYYY.MM.DD>.

.gitea/workflows/image-only.yml: on-demand or auto on code-only
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Dockerfile, sources.json). Reindexes from committed corpus, builds
image, pushes. ~10 min vs ~9h full refresh.

.gitignore: corpus/ now COMMITTED (4,159 labels, 265 MB of .md +
sidecars). Lets image-only.yml rebuild indexes without re-scraping.
chroma/ + bm25/ still gitignored (regenerable binary indexes).

.dockerignore: drops venv, eval results, PLAN/README/CLAUDE.md,
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explicitly NOT in dockerignore (those go INTO the image).

Co-Authored-By: Claude Opus 4.7 (1M context) <noreply@anthropic.com>
2026-05-24 12:32:41 -04:00

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# AFLA-GUARD GR
- EPA Reg No: **100-1469**
- Registrant: SYNGENTA CROP PROTECTION, LLC
- Signal word: Caution
- Active ingredients: Aspergillus flavus NRRL 21882 (0.0094%)
- Label accepted: 2021-03-16
- Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000100-01469-20210316.pdf
---
UNITED STATES ENVIRONMENTAL PROTECTION AGENCY
WASHINGTON, D.C. 20460
OFFICE OF CHEMICAL SAFETY
AND POLLUTION PREVENTION
March 16, 2021
Charles Levey
US Regulatory Team Lead Insecticides
Syngenta Crop Protection, LLC
P.O. Box 18300
Greensboro, NC 27519
Subject: Non-Pesticide Registration Improve ment Act (PRIA) Labeling Amendment Add
Organic Production Language and OMRI Logo
Product Name: Afla-Guard GR
EPA Registration Number: 100-1469
Application Date: October 9, 2020
OPP Case Number: 00144417
Dear Mr. Levey:
The amended labeling referred to above, submitted in connection with registration under the Federal
Insecticide, Fungicide, and Rodenticide Act (FIFRA), as amended, is acceptable under FIFRA section
3(c)(5).
You must submit and/or cite all data required for registration or registration review of your product
when the U.S. Environmental Protection Agency (EPA) requires all registrants of similar products to
submit such data.
A stamped copy of your labeling is enclosed for your records. This labeling supersedes all previously
accepted labeling. You must submit one (1) copy of the final printed labeling before you release this
product for shipment with the new labeling. In accordance with 40 CFR § 152.130(c), you may
distribute or sell this product under the previously approved labeling for 18 months from the date of this
letter. After 18 months, you may only distribute or sell this product if it bears this new revised labeling
or subsequently approved labeling. “To distribute or sell” is defined under FIFRA section 2(gg) and its
implementing regulation at 40 CFR § 152.3.
Should you wish to add/retain a reference to your companys website on your label, then please be
aware that the website becomes labeling under FIFRA and is subject to review by the EPA. If the
website is false or misleading, the product will be considered to be misbranded and sale or distribution
of the product is unlawful under FIFRA section 12(a)(1)(E). 40 CFR § 156.10(a)(5) lists examples of
statements the EPA may consider false or misleading. In addition, regardless of whether a website is
referenced on your products label, claims made on the website may not substantially differ from those
Page 2 of 2
EPA Reg. No. 100-1469
OPP Case No. 00144417
claims approved through the registration process. Therefore, should the EPA find or if it is brought to
our attention that a website contains false or misleading statements or claims substantially differing from
the EPA-approved registration, the website will be referred to the EPAs Office of Enforcement and
Compliance Assurance.
Your release for shipment of this product constitutes acceptance of these terms. If these terms are not
complied with, this registration will be subject to cancellation in accordance with FIFRA section 6.
If you have any questions, please contact Daniel Schoeff by phone at (703) 347-0143 or via email at
schoeff.daniel@epa.gov.
Sincerely,
Alexandra Boukedes, Risk Manager
Microbial Pesticides Branch
Biopesticides and Pollution
Prevention Division (7511P)
Office of Pesticide Programs
Enclosure
Afla-Guard GR
Page 1
[Master]
Afla-Guard® GR
For agricultural use to displace aflatoxin-producing fungi in almonds, peanuts,
pistachios, and corn
[OMRI Listed][For Use in Organic Production][For Organic Production]
Active Ingredient:
Aspergillus flavus NRRL 21882* ........................................................................ 0.0094%
Other Ingredients: …………………………………………………………………... 99.9906%
Total: 100.0000%
*Contains a minimum of 1.2 x 108 CFU/lb of product
KEEP OUT OF REACH OF CHILDREN
CAUTION
See additional precautionary statements and directions for use on the container label [to
the right].
EPA Reg. No. 100-1469
EPA Est.
Manufactured for:
Syngenta Crop Protection, LLC
P. O. Box 18300
Greensboro, North Carolina 27419-8300
Not for sale or use after __________ [Date stamped/placed on labeling will be 4 months
after the date of manufacture.]
Lot No.: ________________________
______ Pounds
Net Weight
Mar 16, 2021
100-1469
Afla-Guard GR
Page 2
FIRST AID
If in eyes x Hold eye open and rinse slowly and gently with water for 15-20
minutes.
x Remove contact lenses, if present, after the first 5 minutes, then
continue rinsing eye.
x Call a poison control center or doctor for treatment advice.
If on skin or
clothing
x Take off contaminated clothing.
x Rinse skin immediately with plenty of water for 15-20 minutes.
x Call a poison control center or doctor for treatment advice.
If swallowed x Call a poison control center or doctor immediately for treatment
advice.
x Have person sip a glass of water if able to swallow.
x Do not induce vomiting unless told to do so by a poison control
center or doctor.
x Do not give anything by mouth to an unconscious person.
If inhaled x Move person to fresh air.
x If person is not breathing, call 911 or an ambulance, then give
artificial respiration, preferably by mouth-to-mouth, if possible.
x Call a poison control center or doctor for treatment advice.
Have the product container or label with you when calling a poison control center or
doctor, or going for treatment.
HOTLINE NUMBER
For 24-Hour Medical Emergency Assistance (Human or Animal) or
Chemical Emergency Assistance (Spill, Leak, Fire, or Accident),
Call
1-800-888-8372
PRECAUTIONARY STATEMENTS
Hazards to Humans and Domestic Animals
CAUTION
Causes moderate eye irritation. Harmful if absorbed through skin, swallowed, or
inhaled. Prolonged or frequently repeated skin contact may cause allergic reactions in
some individuals. Avoid contact with skin, eyes, or clothing. Avoid breathing dust.
Wash thoroughly with soap and water after handling and before eating, drinking,
chewing gum, using tobacco, or using the toilet. Remove and wash contaminated
clothing before reuse.
Afla-Guard GR
Page 3
Personal Protective Equipment (PPE)
Applicators, mixers, loaders and other handlers must wear:
x Long-sleeved shirt and long pants
x Waterproof gloves
x Shoes plus socks
x Goggles
Mixers/loaders and applicators must wear a NIOSH-approved particulate respirator with
any N, R or P filter with NIOSH approval number prefix TC-84A; or a NIOSH-approved
powered air purifying respirator with an HE filter with NIOSH approval number prefix
TC-21C. Repeated exposure to high concentrations of microbial proteins can cause
allergic sensitization.
Follow the manufacturers instructions for cleaning/maintaining PPE. If no instructions
are available, use detergent and hot water for washables. Keep and wash PPE
separately from other laundry.
User Safety Recommendations
Users should:
x Remove clothing/PPE immediately if pesticide gets inside. Then wash
thoroughly and put on clean clothing.
x Remove PPE immediately after handling this product. Wash the outside of
gloves before removing. As soon as possible, wash thoroughly and change
into clean clothin
g.
Environmental Hazards
For terrestrial uses: Do not apply directly to water, or to areas where surface water is
present, or to intertidal areas below the mean highwater mark. Do not contaminate
water by cleaning equipment or disposal of equipment washwater or rinsate.
DIRECTIONS FOR USE
It is a violation of Federal law to apply this product in a manner inconsistent with its
labeling. Do not apply this product in a way that will contact workers or other persons,
either directly or through drift. Only protected handlers may be in the area during
application. Do not apply in the vicinity of schools, daycares, nursing homes and
residential areas. For any requirements specific to your State or Tribe, consult the State
or Tribal agency responsible for pesticide regulation.
Afla-Guard GR
Page 4
PRODUCT INFORMATION
Afla-Guard GR is a biological control agent for displacing the strains of Aspergillus
flavus (A. flavus). The active ingredient in Afla-Guard GR is a nontoxigenic strain of A.
flavus (NRRL 21882). Afla-Guard GR acts by competitively displacing toxigenic,
aflatoxin-producing strains of A. flavus on labeled crops. Afla-Guard GR is for use on
[almonds, peanuts, pistachios, and corn (field and popcorn)] only.
AGRICULTURAL USE REQUIREMENTS
Use this product only in accordance with the Worker Protection Standard, 40 CFR
Part 170. This Standard contains requirements for the protection of agricultural
workers on farms, forests, nurseries, and greenhouses, and, handlers of agricultural
pesticides. It contains requirements for training, decontamination, notification, and
emergency assistance. It also contains specific instructions and exceptions
pertaining to the statement on this label about personal protective equipment (PPE),
and restricted-entry interval. The requirements in this box only apply to uses of this
product that are covered by the Worker Protection Standard.
Do not enter or allow worker entry into treated areas during the restricted entry
interval (REI) of 4 hours.
PPE required for early entry to treated areas (that is permitted under the Worker
Protection Standard and that involves contact with anything that has been treated,
such as plants, soil, or water), is:
x Coveralls
x Waterproof gloves
x Shoes plus socks
x
A NIOSH-approved particulate respirator wi th any N, R or P filter with NIOSH
approval number prefix TC-84A; or a NIOSH- approved powered air purifying
respirator with an HE filter with NIOSH approval number prefix TC-21C
x Goggles
USE DIRECTIONS
For aerial applications: Avoiding drift at the application site is the responsibility of the
applicator. The interaction of many equipment- and weather-related factors determine
the potential for drift. The applicator and treatment coordinator are responsible for
considering all these factors when making decisions.
Peanuts
Ground Application: Apply Afla-Guard GR at 20 lb/Acre (A) in a band over crop rows
by using a tractor-mounted Gandy box or by broadcast application. Apply at full canopy
(40-80 days after planting). At the time of application, the width of a peanut row
(measured from the outer edges of the foliage canopy) is ideally about 18 inches.
Afla-Guard GR
Page 5
Aerial Application: Apply by air at 20 lb/A broadcast. Apply as soon as practical after
closure of the peanut canopy, within 90 days after planting.
Do not exceed 20 lb/A per growing season.
Corn (field corn and popcorn)
Ground and Aerial Application: Apply Afla-Guard GR from growth stage V7 to R1
(the V7 growth stage is when there are 7 visible leaf collars present and the R1 growth
stage is the onset of silking) using broadcast application equipment. Cultivation or other
mechanical operations that may move soil so that it covers the Afla-Guard GR grain
may preclude maximum performance. Therefore, DO NOT APPLY AFLA-GUARD GR
UNTIL ALL CULTIVATION OR OTHER MECHANICAL OPERATIONS ARE
COMPLETED.
Do not exceed 20 lb/A per growing season.
Apply Afla-Guard GR at a use rate of 10-20 lb/A.
Under environmental conditions that promote severe aflatoxin levels or when historically
high levels of aflatoxin have occurred in the past in your area, use the 20 lb/A rate.
Rescue treatment: If an initial rate of 10 lb/A was applied, a rescue treatment of 10 lb/A
may follow if environmental conditions are anticipated to reduce the efficacy of Afla-
Guard GR (i.e. flooding), or when higher than usual levels of aflatoxin are expected.
Almond and Pistachio
Ground Application:
1. Apply Afla-Guard GR to the surface of the soil under the plant canopy with a
granular applicator. DO NOT COVER THE APPLIED PRODUCT WITH SOIL.
2. Adjust the applicator to optimize delivery of Afla-Guard GR under the canopy and
to minimize delivery of Afla-Guard GR to areas that do not get wet.
3. Afla-Guard GR has been shown to be effective when applied in Pistachio from
late May through early July, and in Almond from late May through early July.
4. Rain or irrigation within 3 days after application of Afla-Guard GR will improve
results.
5. Use 10 lb of Afla-Guard GR per acre.
6. Do not apply more than once per year.
7. Do not apply to almonds in bloom.
STORAGE AND DISPOSAL
Do not contaminate water, food, or feed by storage or disposal.
Pesticide Storage: Store in a dry, cool place out of direct sunlight and away from heat
sources. Keep from overheating. Storage temperatures are not to exceed 90ºF. Do
not use product more than 4 months after purchase or save product for use in the
subsequent season.
Afla-Guard GR
Page 6
Pesticide Disposal: To avoid waste, use all material in this container by application
according to label directions. If waste cannot be avoided, offer remaining products to a
waste disposal facility or pesticide disposal program (often such programs are run by
state or local governments or by industry).
Container Handling: Nonrefillable container. Do not reuse or refill this container.
Completely empty bag into application equipment by shaking and tapping the sides and
bottom to loosen clinging particles. Then dispose of empty bag in a sanitary landfill or
by incineration, or if allowed by state and local authorities, by burning. If burned, stay
out of smoke. Do not rec
ycle.
CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY
NOTICE: Read the entire Directions for Use and Conditions of Sale and Limitation of
Warranty and Liability before buying or using this product. If the terms are not
acceptable, return the product at once, unopened, and the purchase price will be
refunded.
The Directions for Use of this product must be followed carefully. It is impossible to
eliminate all risks inherently associated with the use of this product. Crop injury,
ineffectiveness or other unintended consequences may result because of such factors
as manner of use or application, weather or crop conditions, presence of other materials
or other influencing factors in the use of the product, which are beyond the control of
SYNGENTA CROP PROTECTION, LLC (hereafter SYNGENTA) or Seller. To the
extent permitted by applicable law, Buyer and User agree to hold SYNGENTA and
Seller harmless for any claims relating to such factors.
SYNGENTA warrants that this product conforms to the chemical description on the label
and is reasonably fit for the purposes stated in the Directions for Use, subject to the
inherent risks referred to above, when used in accordance with directions under normal
use conditions. To the extent permitted by applicable law: (1) this warranty does not
extend to the use of the product contrary to label instructions, or under conditions not
reasonably foreseeable to or beyond the control of Seller or SYNGENTA, and (2) Buyer
and User assume the risk of any such use. TO THE EXTENT PERMITTED BY
APPLICABLE LAW, SYNGENTA MAKES NO WARRANTIES OF MERCHANTABILITY
OR OF FITNESS FOR A PARTICULAR PURPOSE NOR ANY OTHER EXPRESS OR
IMPLIED WARRANTY EXCEPT AS WARRANTED BY THIS LABEL.
To the extent permitted by applicable law, in no event shall SYNGENTA be liable for
any incidental, consequential or special damages resulting from the use or handling of
this product. TO THE EXTENT PERMITTED BY APPLICABLE LAW, THE
EXCLUSIVE REMEDY OF THE USER OR BUYER, AND THE EXCLUSIVE LIABILITY
OF SYNGENTA AND SELLER FOR ANY AND ALL CLAIMS, LOSSES, INJURIES
OR DAMAGES (INCLUDING CLAIMS BASED ON BREACH OF WARRANTY,
CONTRACT, NEGLIGENCE, TORT, STRICT LIABILITY OR OTHERWISE)
RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, SHALL BE THE
RETURN OF THE PURCHASE PRICE OF THE PRODUCT OR, AT THE ELECTION
OF SYNGENTA OR SELLER, THE REPLACEMENT OF THE PRODUCT.
SYNGENTA and Seller offer this product, and Buyer and User accept it, subject to the
foregoing Conditions of Sale and Limitation of Warranty and Liability, which may not be
Afla-Guard GR
Page 7
modified except by written agreement signed by a duly authorized representative of
SYNGENTA.
Afla-Guard®, The ALLIANCE FRAME, the SYNGENTA Logo, and the PURPOSE ICON
are Trademarks of a Syngenta Group Company
Afla-Guard GR 1469 MAS 0920-AMEND-B-1020-CL em 3/9/2021
000100-01469.20201001.AFLA-GUARD_GR-AMEND-B-1020-CL.pdf