crop-chem-docs/corpus/epa_ppls/100-1522.md

# SOYACYST WP PLUS

- EPA Reg No: **100-1522**
- Registrant: SYNGENTA CROP PROTECTION, LLC
- Signal word: Caution
- Active ingredients: Pasteuria nishizawae Pn1 (100%)
- Label accepted: 2021-11-01
- Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000100-01522-20211101.pdf

---
UNI
TED STATES ENVIRONMENTAL PROTECTION AGENCY 
WASHINGTON, D.C. 20460 
OFFICE OF CHEMICAL SAFETY 
AND POLLUTION PREVENTION 
November 1, 2021 
D
avis Daiker 
Syngenta Crop Protection, LLC 
Regulatory Product Manager 
P.O. Box 18300 
Greensboro, NC 27419 
S
ubject: Non-PRIA (Pesticide Registration Improvement Act) Labeling Amendment – Add a Six-
Month Expiration Date on the Label and Make Other Label Changes to Algin with 
Current Label Standards 
Product Name: Soyacyst WP Plus 
EPA Registration Number: 100-1522 
Application Date: 01/24/2020 
Action Code Case Number: 00074853 
D
ear Mr. Daiker: 
T
he amended labeling referred to above, submitted in connection with registration under the Federal 
Insecticide, Fungicide, and Rodenticide Act (FIFRA), as amended, is acceptable. 
T
his approval does not affect any terms or conditions that were previously imposed on this registration. 
You continue to be subject to existing terms or conditions on your registration and any deadlines 
connected with them. 
A
 stamped copy of your labeling is enclosed for your records. This labeling supersedes all previously 
accepted labeling. You must submit one (1) copy of the final printed labeling before you release this 
product for shipment with the new labeling. In accordance with 40 CFR § 152.130(c), you may 
distribute or sell this product under the previously approved labeling for 18 months from the date of this 
letter. After 18 months, you may only distribute or sell this product if it bears this new revised labeling 
or subsequently approved labeling. “To distribute or sell” is defined under FIFRA section 2(gg) and its 
implementing regulation at 40 CFR § 152.3. 
S
hould you wish to add/retain a reference to your company’s website on your label, then please be 
aware that the website becomes labeling under FIFRA and is subject to review by the U.S. 
Environmental Protection Agency (EPA). If the website is false or misleading, the product will be 
considered to be misbranded and sale or distribution of the product is unlawful under FIFRA section 
12(a)(1)(E). 40 CFR § 156.10(a)(5) lists examples of statements the EPA may consider false or 
misleading. In addition, regardless of whether a website is referenced on your product’s label, claims 
made on the website may not substantially differ from those claims approved through the registration 
process. Therefore, should the EPA find or if it is brought to our attention that a website contains false

Page 2 of 2 
EPA Reg. No. 100-1522 
Action Code Case No. 00074853 
or misleading statements or claims substantially differing from the EPA-approved registration, the 
website will be referred to the EPA’s Office of Enforcement and Compliance Assurance. 
Your release for shipment of this product constitutes acceptance of these terms. If these terms are not 
complied with, this registration will be subject to cancellation in accordance with FIFRA section 6. 
If you have any questions, please contact me by phone at (202) 566-1511 or via email at 
boukedes.alexandra@epa.gov. 
Sincerely, 
A
lexandra Boukedes, Acting Senior Regulatory Advisor 
Microbial Pesticides Branch 
Biopesticides and Pollution 
Prevention Division (7511P) 
Office of Pesticide Programs 
E
nclosure

(Master) 
 
SOYACYST™ WP Plus 
[Alternate Brand Name: Clariva® pn WP] 
 
Biological control for use on soybean seed against soybean cyst nematode 
 
Active Ingredient: 
Pasteuria nishizawae – Pn1* .................................................................... 100.0% 
Other Ingredients: 0.0% 
Total: ............................................................... ....................................... 100.0% 
* Contains at least 1 x 1011 spores per gram or 4.5 x 1012 spores per pound of product. 
 
 
KEEP OUT OF REACH OF CHILDREN 
 
CAUTION 
 
FIRST AID 
If inhaled • Move person to fresh air. 
• If person is not breathing, call 911 or an ambulance, then 
give artificial respiration, preferably by mouth-to-mouth if 
possible. 
• Call a poison control center or doctor for treatment 
advice. 
Have the product container or label with you when calling a poison control center 
or doctor, or going for treatment. 
HOTLINE NUMBER 
For 24-Hour Medical Emergency Assistance (Human or Animal) 
Or Chemical Emergency Assistance (Spill, Leak, Fire or Accident) 
Call 
1-800-888-8372 
 
See additional precautionary and first aid statements [on the back panel] [below] 
[on label] [in booklet]. 
 
Net Weight: 10 lbs, 25 lbs, 50 lbs, or 55 lbs (25 kgs) 
 
EPA Reg. No.: 100-1522 
EPA Est. no.: 
 
 
Not for sale or use after [Date stamped/placed on labeling will be 6 months after 
the date of manufacture] 
Batch Code: 
Nov 01, 2021
100-1522

PRECAUTIONARY STATEMENTS 
 
Hazards to Humans and Domestic Animals 
 
CAUTION 
 
Harmful if inhaled. Avoid breathing dust or spray mist. Remove and wash 
contaminated clothing before reuse. 
 
 
Personal Protective Equipment (PPE) 
 
Applicators and other handlers must wear: 
 
• Long-sleeved shirt and long pants 
• Waterproof gloves 
• Shoes plus socks 
 
Mixers/loaders and applicators must wear a NIOSH -approved particulate 
respirator with any N, R or P filter with NIOSH approval number prefix TC -84A; or 
a NIOSH-approved powered air purifying respirator with an HE filter with NIOSH 
approval number prefix TC -21C. Repeated exposure to high concentrati ons of 
microbial proteins can cause allergic sensitization. 
Follow the manufacturer’s instructions for cleaning/maintaining PPE. If no such 
instructions for washables, use detergent and hot water. Keep and wash PPE 
separately from other laundry . 
 
USER SAFETY RECOMMENDATIONS 
Users should: 
 • Wash hands before eating, drinking, chewing gum, using tobacco or using 
the toilet. 
 • Remove clothing/PPE immediately if pesticide gets inside. Then wash 
thoroughly and put on clean clothing. 
 • Remove PPE immediately after handling this product. As soon as possible, 
wash thoroughly and change into clean clothing. 
 
 
Environmental Hazards 
[Environmental hazards statements for the following container sizes: 10 pounds 
and 25 pounds] 
 
For terrestrial uses: Do not apply directly to water, or to areas where surface water 
is present or to intertidal areas below the mean high water mark. Do not 
contaminate water when disposing of equipment washwater or rinsate.

[Environmental hazards statements for the following container sizes: 50 pounds or 
55 pounds (25 kilograms)] 
 
For terrestrial uses: Do not apply directly to water, or to areas where surface water 
is present or to intertidal areas below the mean high water mark. Do not 
contaminate water when disposing of equipment washwater or rinsate. 
 
Do not discharge effluent containing this product into lakes, streams, ponds, 
estuaries, oceans, or other waters unless in accordance with the requirements of a 
National Pollutant Discharge Elimination System (NPDES) permit and the 
permitting authority has been notified in writing prior to discharge. Do not 
discharge effluent containing this product to sewer systems without previously 
notifying the local sewage treatment plant authority. For guidance, contact your 
State Water Board or Regional Office of EPA.

DIRECTIONS FOR USE 
 
It is a violation of Federal law to use this product in a manner inconsistent 
with its labeling. 
 
Do not use this product until you have read the entire label. Do not apply this 
product in a way that will contact workers or other persons, either directly or 
through drift. Only protected handlers may be in the area during application. For 
any requirement specific to your State or Tribe, consult the State or Tribal agency 
responsible for pesticide regulation. 
 
AGRICULTURAL USE REQUIREMENTS 
 
Use this product only in accordance with its labeling and with the Worker 
Protection Standard, 40 CFR part 170. This Standard contains requirements for 
the protection of agricultural workers on farms, forests, nurseries, and 
greenhouses, and handlers of agricultural pesticides. It contains requirements for 
training, decontamination, notification, and emergency assistance. It also contains 
specific instructions and exceptions pertaining to the statements on this label 
about personal protective equipment (PPE) and restricted-entry interval. The 
requirements in this box only apply to uses of this product that are covered by the 
Worker Protection Standard (WPS). 
 
Do not enter or allow worker entry into treated areas during the restricted-
entry interval (REI) of 4 hours. Exception: If the product is soil injected or soil 
incorporated, the Worker Protection Standard, under certain circumstances, allows 
workers to enter the treated area if there will be no contact with anything that has 
been treated. 
For early entry into treated areas that is permitted under the Worker Protection 
Standard and that involves contact with anything that has been treated, such as 
plants, soil, or water, wear: 
• Waterproof gloves 
• Coveralls 
• Shoes plus socks 
 
 
NON-AGRICULTURAL USE REQUIREMENTS 
 
The requirements in this box apply to uses of this product that are NOT within the 
scope of the Worker Protection Standard for agricultural pesticides (40 CFR Part 
170). The WPS applies when this product is used to produce agricultural plants on 
farms, forests, nurseries or greenhouses.

Keep unprotected persons out of treatment areas until seeds have dried or been 
packaged. 
 
 
 
PRODUCT INFORMATION 
 
This product is a biological nematicide for the control of labeled plant-parasitic 
nematodes. Apply the product as a seed treatment prior to planting. The degree of 
control and nematode suppression depends upon the timing, rate, nematode 
species and soil type. Mobility of this product in the soil is influenced by the 
amount of rainfall/irrigation and the soil type. It will only control those nematodes 
that come into contact with the bacterium. This product is for the control of the 
following nematode: 
 
Soybean Cyst Nematode Heterodera glycines 
 
 
FOR USE AS A SEED TREATMENT 
 
Treatment of highly mechanically scarred or damaged seed, or seed known to be 
of low vigor and poor quality, except for the purpose of curative control of existing 
disease pests, may result in reduced germination and/or reduction of seed and 
seedling vigor. Treat a small quantity of seed using equipment similar to that 
planned for treating the total seed lot. Conduct germination tests on a small 
portion of seed before committing the total seed lot to a selected seed treatment. 
Due to seed quality, crop or variety sensitivity, and seed storage conditions 
beyond the control of manufacturer, no claims are made to guarantee the 
germination of carry-over seed or propagating material for all crop seed. 
 
 
FOR USE AS A PRE-PLANT ON FARM SEED TREATMENT 
 
Do not use treated seed for food or feed purposes or process for oil. Treat only 
those seeds needed for immediate use, minimizing the interval between treatment 
and planting. Do not store excess treated seed beyond planting time. 
 
To achieve improved application coverage to the seed, dilute SOYACYST ™ WP 
Plus with water and apply directly to dry seed or mix with inoculants and/or other 
registered seed treatment coatings (e.g., colorants, polymers, etc.), insecticides 
and fungicides. Do not mix SOYACYST WP Plus with any product containing a 
label prohibition against such mixing. When tank -mixing with any other registered 
seed treatment insecticide and/or fungicide, alway s read and follow all use 
directions, restrictions, and precautions of both SOYACYST WP Plus and the tank 
mix partner(s). The resulting tank mix must be in accordance with the more

restrictive label limitations and precautions. Do not exceed label ed application 
rates. 
 
SOYBEAN 
 
For control of soybean cyst nematode, apply 0.09 to 3.5 oz of SOYACYST WP 
Plus per 100 lbs (2.5 to 100 grams per 45.4 kg) of soybean seed. 
 
FOR USE AS A COMMERCIAL SEED TREATMENT 
 
To achieve improved application coverage to the seed, dilute SOYACYST WP 
Plus with water and apply directly to dry seed or mix with inoculants and/or other 
registered seed treatment coatings (e.g., colorants, polymers, etc.), insecticides 
and fungicides. Do not mix SOYACYST WP Plus with any product containing a 
label prohibition against such mixing. When tank-mixing with any other registered 
seed treatment insecticide and/or fungicide, always read and follow all use 
directions, restrictions, and precautions of both SOYACYST WP Plus and the tank 
mix partner(s). The resulting tank mix must be in accordance with the more 
restrictive label limitations and precautions. Do not exceed label dosage rates. 
 
NOTE: This product does not contain dye. All seed treated commercially with this 
product must be colored with an EPA-approved dye or colorant of a suitable color 
to prevent accidental use as food for humans or feed for animals. 
 
The Federal Seed Act requires that bags containing seed treated with this product 
shall be labeled with the following information: “This seed has been treated with 
Pasteuria nishizawae – Pn1. Do not use for food, feed or oil purposes.” 
 
SOYBEAN 
 
For control of soybean cyst nematode, apply 0.09 to 3.5 oz of SOYACYST WP 
Plus per 100 lbs (2.5 to 100 grams per 45.4 kg) of soybean seed.

STORAGE AND DISPOSAL 
 
Do not contaminate water, food, or feed by storage or disposal. 
 
Pesticide Storage 
Store at room temperature . Keep this product tightly closed in its original 
container, when not in use. 
Pesticide Disposal 
To avoid wastes, use all material in this container by application according to label 
directions. If wastes cannot be avoided, offer remaining product to a waste 
disposal facility or pesticide disposal program (often such programs are run by 
state or local governments or by industry). 
 
Container Handling 
Nonrefillable container. Do not reuse or refill this container. Completely empty bag 
into application equipment. Then offer for recycling if available or dispose of empty 
bag in a sanitary landfill, or by incineration. Do not burn, unless allowed by state 
and local ordinances. If burned, stay out of smoke.

CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY 
 
NOTICE: Read the entire Directions for Use and Conditions of Sale and Limitation 
of Warranty and Liability before buying or using this product. If the terms are not 
acceptable, return the product at once, unopened, and the purchase price will be 
refunded. 
 
The Directions for Use of this product must be followed carefully. It is impossible 
to eliminate all risks inherently associated with the use of this product. Crop injury, 
ineffectiveness or other unintended consequences may result because of such 
factors as manner of use or application, weather or crop conditions, presence of 
other materials or other influencing factors in the use of the product, which are 
beyond the control of SYNGENTA CROP PROTECTION, LLC or Seller. To the 
extent permitted by applicable law, Buyer and User agree to hold SYNGENTA and 
Seller harmless for any claims relating to such factors. 
 
SYNGENTA warrants that this product conforms to the chemical description on the 
label and is reasonably fit for the purposes stated in the Directions for Use, subject 
to the inherent risks referred to above, when used in accordance with directions 
under normal use conditions. To the extent permitted by applicable law: (1) this 
warranty does not extend to the use of the product contrary to label instructions, or 
under conditions not reasonably foreseeable to or beyond the control of Seller or 
SYNGENTA, and (2) Buyer and User assume the risk of any such use. TO THE 
EXTENT PERMITTED BY APPLICABLE LAW, SYNGENTA MAKES NO 
WARRANTIES OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR 
PURPOSE NOR ANY OTHER EXPRESS OR IMPLIED WARRANTY EXCEPT AS 
WARRANTED BY THIS LABEL. 
 
To the extent permitted by applicable law, in no event shall SYNGENTA be liable 
for any incidental, consequential or special damages resulting from the use or 
handling of this product. TO THE EXTENT PERMITTED BY APPLICABLE LAW, 
THE EXCLUSIVE REMEDY OF THE USER OR BUYER, AND THE EXCLUSIVE 
LIABILITY OF SYNGENTA AND SELLER FOR ANY AND ALL CLAIMS, 
LOSSES, INJURIES OR DAMAGES (INCLUDING CLAIMS BASED ON 
BREACH OF WARRANTY, CONTRACT, NEGLIGENCE, TORT, STRICT 
LIABILITY OR OTHERWISE) RESULTING FROM THE USE OR HANDLING OF 
THIS PRODUCT, SHALL BE THE RETURN OF THE PURCHASE PRICE OF 
THE PRODUCT OR, AT THE ELECTION OF SYNGENTA OR SELLER, THE 
REPLACEMENT OF THE PRODUCT. 
 
SYNGENTA and Seller offer this product, and Buyer and User accept it, subject to 
the foregoing Conditions of Sale and Limitation of Warranty and Liability, which 
may not be modified except by written agreement signed by a duly authorized 
representative of SYNGENTA.

Soyacyst™ is a trademark of Pasteuria Bioscience, Inc. 
 
Clariva®, the ALLIANCE FRAME, the SYNGENTA Logo, and the PURPOSE 
ICON are Trademarks of a Syngenta Group Company 
 
©20XX Syngenta 
 
 
For non-emergency (e.g., current product information), call 
Syngenta Crop Protection at 1-800-334-9481. 
 
 
Manufactured for: 
Syngenta Crop Protection, LLC 
P.O. Box 18300 
Greensboro, North Carolina, 27419-8300 
 
Soyacyst WP Plus 1522 MAS 0314 AMEND-B 0120-HI – jeb – 08/02/2021 
000100-01522.20200131B.SOYACYST WP PLUS.AMEND.JAN2020-HI