crop-chem-docs/corpus/epa_ppls/100-942.md

# ADAGE 70WS INSECTICIDE

- EPA Reg No: **100-942**
- Registrant: SYNGENTA CROP PROTECTION, LLC
- Signal word: Caution
- Active ingredients: Thiamethoxam (70%)
- Label accepted: 2000-12-04
- Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000100-00942-20001204.pdf

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C,S. E~'1RONME~'T.-\L PRiOTECTION-AGE~~'C~Y~~~~=E=P=A=R=,g=. =N""'=bc<=, =r=D=.="=o=rho=wn=~===="i1~J I 
Offi~ of Pesticide Programs 
R,g;,tr.ti= "";,;on (H7505C) 100-942 DEC 2fJl) 
401 .~f" St, S.W. 
Washing1on, D.C. 20460 
NOTICE OF PESTICIDE: 
..L Registration 
Tom> orho""",,, Conditional 
Name of Pesticide Product: 
._" FlFRA. "_" Reregistration ( .... tuer as amcnucu) - Adage ™ 70WS Insecticide 
Name and Address of Registrant (include ZIP Codel: 
Syngenta Crop Protection, Inc. 
P.O. Box 18300 
Greensboro, NC 27419-8300 
On the basis of information furnished by the registrant. the above named pesticide is hereby registered/reregistered under the Federal 
Insecticide. Fungicide and Rodenticide Act. 
Registration is in no way to be construed as an endorsement or recommendation of this product by the Agency. In order to protect health 
and the environment, the Administrator. on his motion. may at any time suspend or cancel the registration 01 a pesticide in accordance 
with the Act. The acceptance of any name in connection with the registration of a product under this Act is not to be construed as giving 
the registrant a right to exclusive use of the name or to its use if it has been covered by others. 
This product is conditionally registered in accordance with FIFRA sec. 3(c)(7)(C). provided that you submit 
the following data and label revisions: . 
1. Submit and/or cite all data required for registration/registration review of your product when the Agency 
requires all registrants of similar products to submit such data. 
2. Before you release the product for shipment revise the EPA Registration number to read "EPA Reg. No. 
100-942 ". 
3. Submit the following information to satisfy the data gaps in the data base for Thiamethoxam and its 
metabolite. The following information is required within 15 months of the date of this Notice: 
Residue Chemistry: 
860.1340: 
860.1380: 
860.1480: 
860.1900 
860.1300: 
860.1300: 
Modification of Method AG-675 to add microwave extraction ofliver or a new 
enforcement method for liver; additional radiovalidation data for beef liver 
Storage stability data continued to cover the conditions and intervals that plant and 
animal commodity samples were stored (up to 30 months) 
Reanalysis of the cow liver samples from the feeding study using a microwave extraction 
step 
Reanalysis offield rotational crop samples for metabolite CGA-265307 and description 
of storage conditions for future uses 
Plant metabolism study on a leafy vegetable (Crop Group 4 or 5) 
Poultry metabolism study 
4. Submit the following information to satisfY the data gaps in the data base for Thiamethoxam and its 
metablolite. The follo"ing infonnation is required "ithin two years of the date of this Notice: 
Signature of Approving Official: Date: 
OEC 4 2DOO

2 
EPA fonn 8570-6 (EPA reg. No. 100-942) continued from page 1... 
Toxicology Data: 
870.6300: Developmental neurotoxicity study. 
Ecological Effects 
72-4b: Daphnia chronic study repeated to fulfill guideline requirements 
5. Submit two (2) copies of your final printed label for before your release tbe product for shipment. Please 
refer to the A-79 enclosure for a further description of final printed labeling. 
Iftbese conditions are not complied witb, the registration will be subject to cancellation in accordance 
witb FIFRA section 6(e). Your release for shipment oftbe product bearing amended labeling constitutes 
acceptance of tbese conditions. A stamped copy of tbe label is enclosed for your records. 
A stamped copy of tbe label is enclosed for your records. If you have any questions regarding this action, 
please contact Dani Daniel at 703 305-5409. 
Sincerely, 
Kerry Leifer, Acting Chief 
Insecticide-Rodenticide Branch 
Registration Division (7504C)

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2 
EPA Conn 8570-6 (EPA reg. No.1 00-942) continued from page L. 
Toxicology Data: 
870.6300: Developmental neurotoxicity study. 
Ecological Effects 
72-4b: Daphnia chronic study repeated to fulfill guideline requirements 
5. Submit two (2) copies of your final printed label for before your release the product for shipment. Please 
refer to the A-79 enclosure for a further description of final printed labeling. 
If these conditions are not complied with, the registration "ill be subject to cancellation in accordance 
with FIFRA section 6(e). Your release for shipment of the product bearing amended labeling constitutes 
acceptance of these conditions. A stamped copy of the label is enclosed for your records. 
A stamped copy of the label is enclosed for your records. If you have any questions regarding this action, 
please contact Darti Daniel at 703 305-5409. 
Sincerely, 
Kerry Leifer, Acting Chief 
Insecticide-Rodenticide Branch 
Registration Division (7504C)

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Adage"! 70WS 
INSECTICIDE 
(11/30/00) 
(Water Soluble Bags) 
A seed treatment product for control of certain insects on barley, cotton, sorghum and 
wheat 
Active Ingredient: 
Th,amethoxam: (CAS ?\Io. 153719-23-4) ........................ . . .. 70% 
Other Ingredients: 30% 
Total: 100.00% 
Adage 70WS is packaged in I pound water soluble pouches. 
EPA Reg. '-.'0. 100-
, KEEP OUT OF REACH Of CHILDREN, 
CAUTIO"" 
See storage, disposal. and precautionary statements and directions for use inside booklet. 
L.S Standard \\easure 
:-';CP 
ACCEPTED 
, with COMMENTS 
In EPA Letter Dated: 
I bEe.. -4 .:kDOO 
Vockr l!.e f;-dd·,'.i· Il'._·~,·'.i:idt'. 
Fungicide, UP:: r.~};: .- . .'\, ", 
.. ru:;.:~rrl,·~ :' . . ' ;. ~ 
re,p~kr, . 
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DIRECTIONS FOR USE AND CONDITIONS OF SALE AND LIMITATION OF 
WARRANTY AND LIABILITY 
;liOTleE: Read the entire Directions for Use and Conditions of Sale and Limitation of 
Warranty and LiabilJlY before buying or using this product. If the terms are not acceptable, 
return the product at once, unopened. and the purchase price will be refunded. 
The Directions for l'se of this product should be followed carefully. It is impossible to eliminate 
all flSks inherently associated with the use of this product. Crop inJUry, ineffectiveness or other 
unintended consequences may result because of such factors as manner of use or application. 
weather or crop condJltons. presence of other materials or other influencing factors in the use of 
the product, which are beyond the control of Novartis Crop Protection, Inc. or Seller. All such 
risks shall be assumed by Buyer and User, and Buyer and User agree to hold Novartis and Seller 
harmless for any claims relating to such factors. 
]\;ovartis warrants that this product conforms to the chemical description on the label and is 
reasonably fit for the purposes stated in the Directions for Use, subject to the inherent risks 
referred (0 above. when used in accordance with directions under nonnal use conditions. This 
warranty does not extend to<h~ use of.the product contrary to label instructiMs, or under 
abnoffiJal coo.ditioll&or u~cter cQndition' notn;~onably foreseeabl~ to or be~ond the contro~ of 
.':Selleror Novartis, and BUyer and Uso:r assl\l11etherisk otani' such'!ise: Novarti~ M,;\KES NO 
··WARRANfIES OF MERCHANTABILrrY {)ROF FITNESS FORA PARTICULAR . 
PURPOSE NOR Al\'Y OTHER EXPRESS OR IMPLIED W ARRA:-.ITY EXCEPT AS STA TED 
ABOVE 
In no event shall NO\·artis or Seller be liable for any incidental. consequential or special damages 
resulting from the use or handling of this product. THE EXCLUSIVE REMEDY OF THE USER 
OR BUYER. AND THE EXCLUSIVE LIABILITY OF NOV ARTIS AND SELLER FOR ANY 
AND ALL CLAI~IS. LOSSES, lNJlRlES OR DAMAGES (lNCLUDI:-.IG CLAIMS BASED 
ON BREACH OF WARRANTY. CONTRACT, NEGLIGENCE TORT. STRlCT LIABILITY 
OR OTHERWISE) RESULTING FROM THE USE OR HANDLI:-.IG OF THIS PRODUeT, 
SH.\LL BE THE RETCRt'l OF THE PURCHASE PRlCE OF THE PRODUCT OR. AT THE 
ELECTIO]\; OF NO\·.\RTIS OR SELLER. THE REPLACE\IEl\T OF THE PRODUCT. 
No,ortis and Seller offer this product. and Buyer and Cser accept II. subject to the foreg,'mg 
condilions of sale and limitations of warranty and of liability. ,,·hlch may not be modified except 
by written agreement signed by a duly authorized representative of ~ovartis. 
fJ/rr 
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DIRECTIONS FOR USE 
It is a violation of federal law to use this product in a manner inconsistent with its 
labeling, 
AGRlCUL TURAL USE REQUIREMENTS 
Lse this product only in accordance with its labeling and with the Worker Protection 
Standard, 40 CFR pan 170, This Standard contains requirements for the protection of 
agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of 
agricultural pesticides, It contains requirements for training, decontamination, 
notification, and emergency assistance, It also contains specific instructions and 
exceptions penaining to the statements on this label about persl,nal protective equipment 
(PPE) and restricted-entry interval. The requirements in this box only apply to uses of 
this product that are covered by the Worker Protection Standard, 
Do not enter or allow worker entry into treated areas during I~e restricted entry 
iDterva) (REI) of 1,2 b~urs; Exception; If the s~~d istr\!ated with Ihe product an~ th~ , _ , 
treated seed'is soiT mje'cted onot\ incorporated, the Weirker Protection Standanl, und~r , 
certain circumstances: alieiws workers to enter the treated a'rea if there will 'be no contact 
with anything that has been treated, 
PPE required for early entry to treated areas that is permitted under the Worker Protection 
Standard and that involves contact with anY1hing that has been treated, such as plants. 
I soil. or water is: 
• Coveralls 
• Waterproof gloves 
• Shoes plus soeks 
FAILURE TO fOLLOW THE DIRECTlO\S fOR USE ,~:,\D PRECAUTIONS 
0' THIS LABEL MA Y RESULT IN CROP I:'IIJURY, POOR Ii\SECT AND/OR 
DISEASE CO\TROL, A:'IiD/OR ILLEGAL RESIDUES. 
Treatment of highly mechanically scarred or damaged seed or seed known to be of low 
vigor and poor quality may result in reduced germination and'or reduction of seed and 
seedling vigor. Treat a small quantity of seed using equipment similar to that planned for 
treating the total seed lot. Conduct germination tests on a small ponion 'of seed before 
committmg the total seed lot to a selected seed treatment. Due to seed quality and seed 
swrage conditions beyond the control of\ov'anis, no claims are made to guarantee the 
germination of carry-over seed or propagating material for all crop seed,

GENERAL INFORMA nON 
Adage 70WS is a systemic seed treatment insecticide belonging to the 
neonicotinoid class of chemistry. Adage 70WS controls certain chewing and 
sucking insects following contact and ingestion. When rate ranges are given. use 
higher rates when insect pressure is expected to be high. 
:\lixing Procedures 
Adage 70WS is a wettable powder fonnulated especially for seed treatment uses. Apply 
Adage 70WS as a water based slurry utilizing standard slurry seed treattnent equipment 
which provides unifonn seed coverage. Cneven or incomplete seed coverage may not 
give the desired level of insect control. Thoroughly mix the recommended amount of 
Adage 70WS into the required amount of water for the slurry treater and dilution rate to 
be used. One pound of Adage 70WS displaces II fl. oz of water. Consult the 
manufacturer of the application equipment You plan to use for suitability for this 
application and for Instructions on operati()n and calibration of the equipment. Allow 
. ,seed. to dry. before:bagging. . . . 
' .. ' 
' . .... ". 
Federallaw'"requires 'that'bags'containirtgtreate<.1 ~eed 'shali be 'labeled witli the 
following infonnation: "This seed has been treated WIth thiamethoxam 
insecticide. Do not use for feed. food. or oil purposes. Store away from feed 
and foodstuffs. "Use an EPA·approved dye or colorant that imparts an unnatural 
color to the seed. 
BARLEY 
To provide early season protection of seedlings against injury by bird cherry-oat aphid, 
English grain aphid. Russian wheat aphid. greenbug. HeSSIan fly. and wirewonn and to 
reduce potential spread of barley yellow dwarf virus due to the aphid vectors mentioned 
above. apply Adage 70WS at 0.66-1.2 oz. per 100 Ibs. of seed. 
COTTON (DELINTED ONLY) 
To provide early season protection of seedlings against injury by cotton aphid, western 
flower thrips and tobacco thrips apply Adage 70WS at ~.6 to 6.9 oz .. per 100 Ibs. of seed. 
Plan't Adage treated cotton seed based on Gltes recommended by your state agricultural 
extension agent. In northern cotton grOV\l:1g regions such as ~C and Y.; . or where thrip 
pressure is expected to be severe. use Adage seed treatment followed by foliar sprays of 
Orthene beginning when cotton is at Ihe 1 leaf stage. Follow the Orthene product label 
for rates. use instructions and limitations. 
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SORGHOI 
To provide early season protection of seed I ings against injury by com leaf aphid, yellow 
sugar cane aphid, greenbug, chinch bug, seed com maggot, wireworm, and fire ant apply 
Adage 70WS at 4.6 oz. per 100 Ibs. of seed. 
WHEAT 
To provide early season protection of seedlings against injury by bird cherry-oat aphid, 
English grain aphid, Russian wheat aphid, greenbug, Hessian fly, and wireworm and to 
reduce potential spread of barley yellow dwarf virus due to the aphid wctors mentioned 
above. apply Adage 70WS at 0.66-1.2 oz. per 100 Ibs. of seed. 
Rotational Crops: Treated areas may be replanted Immediately following harvest or as 
soon as practical following the last application with any crop on this label or to cucurbit 
vegetables. fruiting v·egetables. ruberous and corm vegetables and tobacco. For all other 
crops, a I cO-day plantback interval must be observed . . - .. ".' . . 
Pesticide Storage and Disposal 
Store in a cool. dry place. Do not contaminate water. food, or feed by storage, disposal, 
or cleaning of equipment. Wastes resulting from the use' of this product may be disposed 
of on site or at an approv'ed waste disposal facility. If these wastes cannot be used 
according to label instructions, contact your State Pesticide or Env'ironmental Control 
Agency or the Hazardous Waste representative at the ne-arest EPA regional office for 
guidance in proper disposal methods. 
Container Disposal 
Triple rinse (or equiv-alent), then offer for recycling or reconditioning or puncrure and 
dispose of in a sanitary landfill, or by incineration, or by open burning, if allowed by state 
and local authorities. [fburned, keep out of smoke. 
For minor spills, leaks, etc .. follow all pre~autions indicated on this label and clean' up 
immediately. Take special care to avoid cornaminatlon of equipment and facilities during 
cleanup procedures and disposal of wastes. In the e\ ent of a major spIlL fire. or other 
emergency. call \-800-888-8372, day or night. 
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PRECAUTIONARY STATEME:'oITS 
Hazards to Humans and Domestic Animals 
CAl'TIO:'-i 
Hannful if swallowed. inhaled, or absorbed through skin. Avoid contact with eyes, skin. 
or clothing, ' A\'oid breathing dust vapor, or spray mist Wash thoroughly wilh soap and 
water after handling. Remove contammated clothing and wash before reuse, 
First Aid 
If inhaled 
· , 
, . ' 
, , Ifin' eyes· 
If on skin or 
clothing 
If swallowed 
• Y10ve the persc)n to fresh air. 
• [fperson is not breathing. call an ambulance, then gIve aI1ifical 
respiration. preferably mouth to mouth, if possible, 
• . Call a poison,comrol center, doctor,or 1-,8QO-S8&-8372 immediately for, 
treatniefi advice, ' ' ,., ." 
• HQld eye open· and·rinse ·sloWly aoogently M'lh water for 15-20 ' 
minutes. 
• Remove contact lenses, if present, and after the first 5 minutes, then 
continue rinsing eye. 
• Call a poison control center, doctor. or 1-800-888-8372 immediately for 
treatment adyice, 
• Take off contaminated clothing. 
• Rinse skin immediately with plenty of water for 15-20 minutes, 
• Call a poison control center. doctor or 1-800-888-8372 immediately for 
treatment ad\lce. 
• Call a poison control center, doctor. or 1-800-888-8372 immediately for 
treatment ad\'ice, 
• Have person SIp a glass of water if able to swallow. 
• Do not induce \'omiting unless told to do so by the poison control center 
or doctor 
Note to Ph~·siCian: There is no specific antidl)te if Adage 70WS is ingesied Induce 
emesis or la\'age stomach Treat s:mptomatically, 
Personal Protection Equipment 
Applicators and other handlers must wear: 
• Covaalls 
• \\" aterproof gloves 
• Shoes plus socks 
1/11

Follow manufacturer's instructions for cleaning/maintaining PPE. Ifno such instructions 
exist for washables, use detergent and hot water. Keep and wash PPE separately from 
other laundry. 
Engineering Control Statements 
When handlers use closed systems, enclosed cabs, or aircraft in a manner that meets the 
requirements listed in the Worker Protection Standard (WPS) for agricultural pesticides 
[40 CFR l70.240(d)(4-6»). the handler PPE requirements may be reduced or modified as 
specified in the WPS. 
. . 
--Note: Workers must ",:€;ar IQng pants, long sleeve sllirti. an" chemical-resiStant gloves 
;"hen applying Adage 70WS as a seed treatment. 
Surface Water .-\dvisory 
This product may contaminate water through drift of spray in wind. This product has a 
high potential for runoff for several months or more after application. Poorly draining 
soils and soils with shallow water tables are more prone to produce runoff that contains 
this product. A level. well maintained vegetative buffer strip between areas to which this 
product is applied and surface water features such as ponds. streams, and streams. and 
springs will reduce the potential for contamination of water from rainfall runoff(See 
manual at the following internet address: 
http: .. www.nrcs.usda.gO\water-quality.commollipestmgtfiles.core4.html). 
Runoff of this product will be reduced by 3\ aiding applications when rainfall is 
. forecasted .to occur within 48 hours. 
Ground Water Advisory 
Thiarnethoxam has properties and charactenstics associated with chem:cals detected in 
ground water. The use of this chemical in areas where soilS are penneable. particularly 
II here the water table is shallow may result in ground water contamination.

Environmental Hazards 
This pesticide is toxic to fish and aquatic invertebrates. Do not apply directly to \\ater, to 
areas where surface water is present, or to intertidal areas below the mean high water 
mark. Drift or runoff from treated areas may be hazardous to aquatic organisms in 
neighboring areas. Do not contaminate water when disposing of equipment wash\\ aters. 
Spray Drift Advisory 
Do not allow this product to drift. 
Adage T " trademark of Nov art is 
e2000 Novartis 
~ovartis Crop Protection. Inc. 
Seed Treatment Products 
Greensboro. North Carolina 27419 
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