crop-chem-docs/corpus/bayer/prosaro-pro-400-sc.md

# Prosaro Pro 400 SC Fungicide

- **Product class:** fungicide
- **EPA Reg No:** 264-1209
- **Active ingredients:** Tebuconazole, Fluopyram, Prothioconazole
- **Source:** https://www.cropscience.bayer.us/crop-protection/fungicide/prosaro-pro-400-sc-fungicide
- **Label PDF:** https://cs-assets.bayer.com/is/content/bayer/Prosaro_PRO_400_SC_Labelpdf

---

Net Contents:
US87306429A         210819A     09/21
US87306429A (210819A)   PROSARO PRO 400 SC 2.5G ETL
COLORS: CMYK     DATE: 09/07/21
Label Coordinator:  Mark Schmidt
For control of specific diseases on listed crops.
Active Ingredients:
Prothioconazole, 2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]
-1,2-dihydro-3H-1,2,4-triazole-3-thione �����������������������������������������������������������������������17.39%
Tebuconazole, alpha-[2-(4-chlorophenyl)ethyl]-alpha-(1,1-dimethylethyl)-
1H-1,2,4-triazole-1-ethanol ��������������������������������������������������������������������������������������������8.70%
Fluopyram, N-[2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl]-2
(trifluoromethyl)benzamide ��������������������������������������������������������������������������������������������8.70%
Other Ingredients:  ����������������������������������������������������������������������������������������������������65.21%
TOTAL:  100.0%
Contains 1�67 pounds of prothioconazole, 0�84 pounds of tebuconazole, and 0�84 pounds
of fluopyram per U�S� gallon
EPA Reg. No. 264-1209
KEEP OUT OF REACH OF CHILDREN
CAUTION
For MEDICAL and TRANSPORTATION Emergencies ONLY
Call 24 Hours A Day 1-800-334-7577
For PRODUCT USE Information Call 1-866-99BAYER (1-866-992-2937)
See Back Panel for First Aid Instructions and Booklet for Complete
Precautionary Statements and Directions for Use.
Produced for
Bayer CropScience LP
800 N� Lindbergh Blvd�
St� Louis, MO 63167
PROSARO® PRO is a registered trademark of Bayer Group�
©2021 Bayer Group
2.5 Gallons
PROTHIOCONAZOLE GROUP
GROUP
GROUP
3
3
7
FUNGICIDE
FUNGICIDE
FUNGICIDE
TEBUCONAZOLE
FLUOPYRAM
400 SC Fungicide

1
FIRST AID
IF SWALLOWED: • Call a poison control center or doctor immediately for
treatment advice�
• Do not induce vomiting unless told to do so by a poison
control center or doctor�
• Have person sip a glass of water if able to swallow�
• Do not give anything by mouth to an unconscious person�
IF ON SKIN OR
CLOTHING:
• Take off contaminated clothing�
• Rinse skin immediately with plenty of water for 15-20
minutes�
• Call a poison control center or doctor for treatment advice�
IF IN EYES: • Hold eye open and rinse slowly and gently with water for
15-20 minutes�
• Remove contact lenses, if present, after the first 5 minutes,
then continue rinsing eye�
• Call a poison control center or doctor for treatment advice�
IF INHALED: • Move person to fresh air�
• If person is not breathing, call 911 or an ambulance, and
then give artificial respiration, preferably mouth-to-mouth if
possible�
• Call a poison control center or doctor for treatment advice�
For MEDICAL Emergencies Call 24 Hours A Day 1-800-334-7577.
Have the product container or label with you when calling a poison control
center or doctor or going for treatment.
NOTE TO PHYSICIAN: No specific antidote� Treat symptomatically�
PRECAUTIONARY STATEMENTS
HAZARDS TO HUMANS AND DOMESTIC ANIMALS
CAUTION
Harmful if swallowed, inhaled, or absorbed through the skin� Causes moderate
eye irritation� Avoid contact with skin, eyes, and clothing� Avoid breathing vapor or
spray mist� Wash thoroughly with soap and water after handling and before eating,
drinking, chewing gum, or using tobacco, or using the toilet� Remove and wash
contaminated clothing before reuse�
Personal Protective Equipment (PPE)
Applicators and other handlers must wear:
• Long-sleeved shirt and long pants
• Chemical resistant gloves made of any waterproof material
• Shoes plus socks
• protective eyewear
Engineering Control Statements
When handlers use closed systems, enclosed cabs, or aircraft in a manner that
meets the requirements listed in the Worker Protection Standard (WPS) for
agricultural pesticides [40 CFR 170�240(d)(4-6)], the handler PPE requirements
may be reduced or modified as specified in the WPS�
USER SAFETY RECOMMENDATIONS
• Users should remove clothing/PPE immediately if pesticide gets inside� Then
wash thoroughly and put on clean clothing�
• Users should remove PPE immediately after handling this product� Wash the
outside of gloves before removing� As soon as possible, wash thoroughly and
change into clean clothing�

2
USER SAFETY REQUIREMENTS
Follow manufacturer’s instructions for cleaning/maintaining PPE� If no such
instructions for washables exist, use detergent and hot water�  Keep and wash PPE
separately from other laundry�
ENVIRONMENTAL HAZARDS
This product is toxic to mammals, fish, aquatic invertebrates, and freshwater/
estuarine/marine aquatic plants� Do not apply directly to water, or to areas where
surface water is present or to intertidal areas below the mean high water mark�
Runoff may be hazardous to aquatic organisms in neighboring areas� Do not
contaminate water when disposing of equipment washwater or rinsate�
Surface Water Advisory
This product may impact surface water quality due to runoff of rain water� This is
especially true for poorly draining soils and soils with shallow ground water� This
product is classified as having high potential for reaching surface water via runoff for
several months or more after application� A level, well-maintained vegetative buffer
strip between areas to which this product is applied and surface water features such as
ponds, streams, and springs will reduce the potential loading of this product from runoff
water and sediment� Runoff of this product will be reduced by avoiding applications
when rainfall or irrigation is expected to occur within 48 hours� Sound erosion control
practices will reduce this product’s potential to reach aquatic sediment via runoff�
Ground Water Advisory
These chemicals have properties and characteristics associated with chemicals
detected in ground water� These chemicals may leach into groundwater if used
in areas where soils are permeable, particularly where the water table is shallow�
Prothioconazole-desthio (a degradate of prothioconazole) and tebuconazole are
known to leach through soil into ground water under certain conditions as a result
of label use� Use of this chemical in areas where soils are permeable, particularly
where the water table is shallow, may result in ground-water contamination�
CONDITIONS OF SALE AND LIMITATIONS OF WARRANTY AND LIABILITY
Read the entire Directions for Use, Conditions, Disclaimer of Warranties and
Limitations of Liability before using this product�  If terms are not acceptable, return
the unopened product container at once�
By using this product, user or buyer accepts the following Conditions, Disclaimer of
Warranties and Limitations of Liability�
CONDITIONS: The directions for use of this product are believed to be adequate
and must be followed carefully� However, it is impossible to eliminate all risks
associated with the use of this product� Crop injury, ineffectiveness or other
unintended consequences may result because of such factors as weather
conditions, presence of other materials, or the manner of use or application, all of
which are beyond the control of Bayer CropScience�  To the extent consistent with
applicable law, all such risks shall be assumed by the user or buyer�
DISCLAIMER OF WARRANTIES:  TO THE EXTENT CONSISTENT WITH
APPLICABLE LAW, BAYER CROPSCIENCE MAKES NO OTHER WARRANTIES,
EXPRESS OR IMPLIED, OF MERCHANTABILITY OR OF FITNESS FOR A
PARTICULAR PURPOSE OR OTHERWISE, THAT EXTEND BEYOND THE
STATEMENTS MADE ON THIS LABEL� No agent of Bayer CropScience is
authorized to make any warranties beyond those contained herein or to modify the
warranties contained herein� TO THE EXTENT CONSISTENT WITH APPLICABLE
LAW, BAYER CROPSCIENCE DISCLAIMS ANY LIABILITY WHATSOEVER FOR
SPECIAL, INCIDENTAL OR CONSEQUENTIAL DAMAGES RESULTING FROM
THE USE OR HANDLING OF THIS PRODUCT�

3
LIMITATIONS OF LIABILITY:  TO THE EXTENT CONSISTENT WITH
APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE USER OR BUYER FOR
ANY AND ALL LOSSES, INJURIES OR DAMAGES RESULTING FROM THE USE
OR HANDLING OF THIS PRODUCT, WHETHER IN CONTRACT, WARRANTY,
TORT, NEGLIGENCE, STRICT LIABILITY OR OTHERWISE, SHALL NOT
EXCEED THE PURCHASE PRICE PAID, OR AT BAYER CROPSCIENCE’S
ELECTION, THE REPLACEMENT OF PRODUCT�
DIRECTIONS FOR USE
It is a violation of federal law to use this product in a manner inconsistent
with its labeling.
Do not apply this product in a way that will contact workers or other persons,
either directly or through drift� Only protected handlers may be in the area during
application� For any requirements specific to your State or Tribe, consult the
agency responsible for pesticide regulation�
Not for sale, distribution, or use in Nassau and Suffolk counties, New York
AGRICULTURAL USE REQUIREMENTS
Use this product only in accordance with its labeling and with the Worker
Protection Standard, 40 CFR part 170� This Standard contains requirements
for the protection of agricultural workers on farms, forests, nurseries, and
greenhouses, and handlers of agricultural pesticides� It contains requirements
for training, decontamination, notification, and emergency assistance� It also
contains specific instructions and exceptions pertaining to the statements on this
label about personal protective equipment (PPE) and restricted-entry interval
(REI)� The requirements in this box only apply to uses of this product that are
covered by the Worker Protection Standard�
Do not enter or allow worker entry into treated areas during the REI of 12 hours�
PPE required for early entry to treated areas that is permitted under the Worker
Protection Standard and that involves contact with anything that has been treated,
such as plants, soil, or water is:
• coveralls over long-sleeved shirt and long pants
• chemical-resistant gloves made of any waterproof material
• chemical-resistant footwear plus socks
• protective eyewear
PRODUCT INFORMATION
• PROSARO PRO 400 SC FUNGICIDE is a broad-spectrum systemic fungicide
for the control of Ascomycetes, Basidiomycetes and Deuteromycetes diseases in
barley, corn (field corn, field corn grown for seed, popcorn, and sweet corn), and
wheat� Under conditions conducive to extended infection periods or high disease
pressure, another registered fungicide may be needed once this product’s
maximum application rates have been reached� Under these conditions use
another fungicide registered for the crop/disease�
USE RESTRICTIONS
• Observe the following restrictions when spraying in the vicinity of aquatic
areas such as lakes, reservoirs, rivers, permanent streams, marshes or
natural ponds, and estuaries.
o Apply only during alternate years in fields adjacent to aquatic areas listed
above�
o Do not apply by ground or air within 100 feet of aquatic areas listed above�
o Do not cultivate within 10 feet of an aquatic area to allow growth of a vegetative
filter strip�

4
o Spray Drift Management: For aerial applications, the spray boom should be
mounted on the aircraft so as to minimize drift caused by wing tip vortices� The
minimum practical boom length should be used, and must not exceed 75% of
the wingspan or rotor diameter�
o Use the largest droplet size consistent with pest control� Formation of very
small droplets may be minimized by appropriate nozzle selection, by orienting
nozzles away from the air stream as much as possible and by avoiding
excessive spray boom pressure�
o Apply in a minimum of 2 gallons of spray solution by acre by aircraft spray
equipment, unless stated differently in the CROP USE DIRECTIONS�
o Spray should be released at the lowest possible height consistent with good
pest control and flight safety� Applications more than 10 feet above the crop
canopy should be avoided�
o Make aerial or ground applications when wind velocity favors on-target
product deposition (approximately 3 to 10 mph)� Do not apply when wind
velocity exceeds 15 mph� Avoid applications when wind gusts approach 15
mph�
o Risk of exposure to sensitive aquatic areas can be reduced by avoiding
applications when wind direction is toward the aquatic area�
o Low humidity and high temperatures increase the evaporation rate of spray
droplets and therefore the likelihood of spray drift to aquatic areas� Avoid
spraying during conditions of low humidity and/or high temperature�
o Do not make aerial or ground applications during temperature inversions�
Inversions are characterized by stable air and increasing temperatures with
height above the ground� Mist or fog may indicate the presence of an inversion
in humid areas� The applicator may detect the presence of an inversion by
producing smoke and observing a smoke layer near the ground surface�
APPLICATION INSTRUCTIONS
• PROSARO PRO 400 SC FUNGICIDE may be applied by either ground,
aerial and/or chemigation application equipment� Equipment must be properly
calibrated before use�
• Complete coverage and uniform application are essential for the most effective
results, especially when lower spray volumes are applied� If necessary, increase
the spray volume per acre for complete crop coverage�
Aerial Application
Apply in a minimum of 2 gallons of spray solution per acre unless stated differently
in the RESTRICTIONS or the CROP USE DIRECTIONS sections� Avoid application
under conditions when uniform coverage cannot be obtained or when excessive
spray drift may occur� Aerial application is prohibited in New York State�
Check equipment calibration frequently�
Ground Application
Apply in a minimum of 10 gallons of spray solution per acre� Complete coverage
and uniform application are essential for the most effective results, especially when
lower spray volumes are applied� If necessary, increase the spray volume per acre
for complete crop coverage�
CHEMIGATION
Apply PROSARO PRO 400 SC FUNGICIDE through irrigation equipment only to
crops for which chemigation is specified on this label�
PROSARO PRO 400 SC FUNGICIDE alone or in combination with other
pesticides, which are registered for application through irrigation systems, may be
applied through irrigation systems� Apply this product only through center pivot,

5
solid set, hand move, or moving wheel irrigation systems� Do not apply this product
through any other type of irrigation system� Illegal pesticide residues in the crop can
result from nonuniform distribution of treated water� If you have questions about
calibration, you should contact State Extension Service specialists, equipment
manufacturers, or other experts� Do not connect an irrigation system (including
greenhouse systems) used for pesticide application to a public water system,
unless the pesticide label-prescribed safety devices for public water systems are in
place� A person knowledgeable of the chemigation system and responsible for its
operation, or under the supervision of the responsible person, shall shut the system
down and make necessary adjustments should the need arise�
Public water system
Public water system’ means a system for the provision to the public of piped water for
human consumption if such system has at least 15 service connections or regularly
serves an average of at least 25 individuals daily at least 60 days out of the year�
Chemigation systems connected to public water systems must contain a functional,
reduced-pressure zone (RPZ), back flow preventer, or the functional equivalent in the
water supply line upstream from the point of pesticide introduction� As an alternative
to the RPZ, the water from the public water system should be discharged into a
reservoir tank prior to pesticide introduction� There shall be a complete physical
break (air gap) between the flow outlet end of the fill pipe and the top or overflow
rim of the reservoir tank of at least twice the inside diameter of the fill pipe� The
pesticide injection pipeline must contain a functional, automatic, quick-closing check
valve to prevent the flow of fluid back toward the injection pump� Pesticide injection
pipeline must contain a functional, normally closed, solenoid-operated valve located
on the intake side of the injection pump and connected to the system interlock to
prevent fluid from being withdrawn from the supply tank when the irrigation system
is either automatically or manually shut down� The systems must contain functional
interlocking controls, to automatically shut off the pesticide injection pump when the
water pump motor stops, or in cases where there is no water pump, when the water
pressure decreases to the point where pesticide distribution is adversely affected�
Systems must use a metering pump, such as a positive displacement injection pump
(e�g�, diaphragm pump) effectively designed and constructed of materials that are
compatible with pesticides and capable of being fitted with a system interlock�
Operating Instructions
1� The system must contain a functional check-valve, vacuum relief valve, and low-
pressure drain appropriately located on the irrigation pipeline to prevent water-
source contamination from backflow�
2� The pesticide injection pipeline must contain a functional, automatic, quick-
closing check-valve to prevent the flow of fluid back toward the injection pump�
3� The pesticide injection pipeline must also contain a functional, normally closed,
solenoid-operated valve located on the intake side of the injection pump and
connected to the system interlock to prevent fluid from being withdrawn from the
supply tank when the irrigation system is either automatically or manually shut down�
4� The system must contain functional interlocking controls to automatically shut off
the pesticide injection pump when the water pump motor stops�
5� The irrigation line or water pump must include a functional pressure switch, which
will stop the water pump motor when the water pressure decreases to the point
where pesticide distribution is adversely affected�
6� Systems must use a metering pump, such as a positive displacement injection
pump (e�g�, diaphragm pump), effectively designed, and constructed of materials
that are compatible with pesticides and capable of being fitted with a system
interlock�
7� Do not apply when wind speed favors drift beyond the area intended for treatment�

6
Center Pivot Irrigation Equipment
Notes: (1) Use only with drive systems, which provide uniform water distribution�
(2) Do not use end guns when chemigating PROSARO PRO 400 SC FUNGICIDE
through center pivot systems because of non-uniform application�
Determine the size of the area to be treated� Determine the time required to apply
1/8-1/2 inch of water over the area to be treated when the system and injection
equipment are operated at normal pressures as recommended by the equipment
manufacturer� When applying PROSARO PRO 400 SC FUNGICIDE through
irrigation equipment use the lowest obtainable water volume while maintaining
uniform distribution� Run the system at 80-95% of the manufacturer’s rated capacity�
Using water, determine the injection pump output when operated at normal line
pressure� Determine the amount of PROSARO PRO 400 SC FUNGICIDE required
to treat the area covered by the irrigation system� Add the required amount of
PROSARO PRO 400 SC FUNGICIDE and sufficient water to meet the injection
time requirements to the solution tank� Make sure the system is fully charged
with water before starting injection of the PROSARO PRO 400 SC FUNGICIDE
solution� Time the injection to last at least as long as it takes to bring the system to
full pressure� Maintain constant solution tank agitation during the injection period�
Continue to operate the system until the PROSARO PRO 400 SC FUNGICIDE
solution has cleared the sprinkler head�
Solid Set, Hand Move, and Moving Wheel Irrigation Equipment
When applying PROSARO PRO 400 SC FUNGICIDE through irrigation equipment
use the lowest obtainable water volume while maintaining uniform distribution�
Determine the amount of PROSARO PRO 400 SC FUNGICIDE required to treat the
area covered by the irrigation system� Add the required amount of PROSARO PRO
400 SC FUNGICIDE into the same quantity of water used to calibrate the injection
period� Operate the system at the same pressure and time interval established
during the calibration� Stop injection equipment after treatment is completed�
Continue to operate the system until the PROSARO PRO 400 SC FUNGICIDE
solution has cleared the last sprinkler head�
Adjuvants: PROSARO PRO 400 SC FUNGICIDE is recommended to be used
with a registered non-ionic surfactant at the lowest specified labeled rate for
most uses� Refer to the USE DIRECTIONS FOR SPECIFIC CROPS for adjuvant
recommendations on corn�
SPRAY DRIFT DIRECTIONS
Do not make applications when conditions favor drift beyond the target application
area� When drift may be a problem, take measures to reduce drift, including:
1� Do not spray if wind speeds are or become excessive� Do not spray if wind speed
is 15 mph or greater� If non-target crops are located downwind, use caution when
spraying if wind is present� Do not spray if winds are gusty�
2� Use caution when conditions are favorable for drift (high temperatures, drought,
and low relative humidity)�
3� Do not apply when temperature inversion exists� If inversion conditions are
suspected, consult with local weather services before making an application�
COMPATIBILITY TESTING AND TANK MIX PARTNERS
Mixing Procedures
Prepare no more spray mixture than is necessary for the immediate operation�
Thoroughly clean spray equipment before using this product� Maintain maximum
agitation throughout the spray operation� Do not let the spray mixture stand overnight
in the spray tank� Flush the spray equipment thoroughly following each use and
apply the rinsate to the previously treated area or dispose of the rinsate according to
local regulations� Do not tank mix with products containing a prohibition against tank
mixing� Follow the most restrictive labeling requirements of any tank mix product�

7
PROSARO PRO 400 SC FUNGICIDE alone: Add ½ of the required amount of
water to the mix tank� With the agitator running, add the PROSARO PRO 400
SC FUNGICIDE to the tank� Continue agitation while adding the remainder of
the water� Begin application of the solution after the product has completely and
uniformly dispersed into the mix water� Maintain agitation until all of the mixture has
been applied�
PROSARO PRO 400 SC FUNGICIDE + Tank-Mix Partners: Add ½ of the required
amount of water to the mix tank� Start the agitator running before adding any of
the tank-mix partners� In general, tank-mix partners should be added in this order:
products packaged in water-soluble packaging*, wettable powders, wettable
granules (dry flowables), liquid flowables, liquids, and emulsifiable concentrates�
Always allow each tank-mix partner to become fully and uniformly dispersed before
adding the next product� Provide sufficient agitation while adding the remainder of
the water� Maintain agitation until all of the mixture has been applied�
* Note: When using PROSARO PRO 400 SC FUNGICIDE in tank mixtures, all
products in water-soluble packaging should be added to the tank before any other
tank-mix partner, including PROSARO PRO 400 SC FUNGICIDE� Allow the water-
soluble packaging to completely disperse before adding any other tank-mix partner
to the tank�
If using PROSARO PRO 400 SC FUNGICIDE in a tank mixture, observe
all directions for use, crop/sites, use rates, dilution ratios, precautions, and
limitations; which appear on the tank-mix product label� Label dosage rate must
not be exceeded, and the most restrictive label precautions and limitations must
be followed� This product must not be mixed with any product that prohibits such
mixing� Tank mixtures or other applications of products referenced on this label
are permitted only in those states in which the referenced products are registered�
PROSARO PRO 400 SC FUNGICIDE is compatible with most insecticide, fungicide,
herbicide, and foliar nutrient products� However, the physical compatibility of
PROSARO PRO 400 SC FUNGICIDE with tank-mix partners should be tested
before use� To determine the physical compatibility of PROSARO PRO 400 SC
FUNGICIDE with other products, use a jar test, as described below�
Using a quart jar, add the proportionate amounts of the products to 1 qt� of water�
Add wettable powders and water-dispersible granular products first, then liquids
and emulsifiable concentrates last� After thoroughly mixing, let stand for at least 5
minutes� If the combination remains mixed or can be remixed readily, it is physically
compatible� Once compatibility has been proven, use the same procedure for
adding required ingredients to the spray tank� For further information, contact your
local Bayer Crop Science representative�
The crop safety of all potential tank mixes including additives and other pesticides
on all crops has not been tested� Before applying any tank mixture not specified on
this label, the safety to the target crop should be confirmed� To test for crop safety,
apply PROSARO PRO 400 SC FUNGICIDE to the target crop in a small area and
in accordance with label instructions for the target crop�
FUNGICIDE RESISTANCE MANAGEMENT (FRAC) RECOMMENDATIONS
For resistance management, please note that PROSARO PRO 400 SC FUNGICIDE
contains both Group 3 (prothioconazole and tebuconazole) and Group 7
(fluopyram) fungicides� Any fungal population may contain individuals naturally
resistant to PROSARO PRO 400 SC FUNGICIDE and other Group 3 and Group
7 fungicides� A gradual or total loss of pest control may occur over time if these
(fungicides) are used repeatedly in the same fields� Appropriate resistance-
management strategies should be followed�

8
To delay fungicide resistance, take one or more of the following steps:
• Rotate the use of PROSARO PRO 400 SC FUNGICIDE fungicide within a
growing season with other fungicide groups that control the same pathogens�
• Use tank mixtures with fungicide from a different group that are equally effective
on the target pest when such use is permitted�
• Use at least the minimum application rate as labeled by the manufacturer�
• Adopt an integrated disease management program for fungicide use that includes
scouting, uses historical information related to pesticide use, and crop rotation,
and which considers host plant resistance, impact of environmental conditions on
disease development, disease thresholds, as well as cultural, biological and other
chemical control practices�
• Where possible, make use of predictive disease models to effectively time
fungicide applications� Note that using predictive models alone is not sufficient to
manage resistance�
• Monitor treated fungal/bacterial populations for resistance development�
• Contact your local extension specialist or certified crop advisor for any additional
pesticide resistance-management and/or IPM recommendations for specific
crops and pathogens�
• For further information or to report suspected resistance contact Bayer
CropScience at 1-866-99BAYER (1-866-992-2937)� You can also contact your
pesticide distributor or university extension specialist to report resistance�
ROTATIONAL RESTRICTIONS
Treated areas may be replanted with barley, corn (field corn, field corn grown for
seed, and popcorn), dry beans (except cowpea), peanuts, soybeans, triticale, and
wheat as soon as practical after last application� Do not rotate to sweet corn within
30 days of the last application� The following crops can be replanted 120 days after
the last application of PROSARO PRO 400 SC FUNGICIDE�  Do not rotate to crops
other than those listed below:
Additional cereals not listed on this label, Alfalfa, Artichoke, (Globe); Brassica (cole)
leafy vegetables (group 5); Bulb vegetables (group 3-07); Carrot; Citrus (group 10-
10); Cotton (subgroup 20C); Cucurbits (group 9); Dill seed; Fruiting Vegetables
(group 8-10); Ginseng; Grapes and small vines (except fuzzy kiwifruit) (subgroup
13-07F); Herb (subgroup 19A); Hops; Leafy vegetables (except watercress) (group
4); Legume Vegetables (except cowpea and dried peas); Pome fruit (group 11-
10); Potato and other root, tuberous and corm vegetables (except sugarbeet)
(subgroups 1B and 1C); Rapeseed (subgroup 20A); Small Berries (caneberries
and bushberries) (subgroups 13-07A and 13-07B); Stone Fruits (group 12-12);
Strawberry and other low-growing berries, except cranberry (subgroup 13-07G);
Sugarbeet; Sugarcane (Region 3); Sunflower (subgroup 20B); Tobacco; Tree Nuts
(group 14-12)�

9
CROP USE DIRECTIONS
BARLEY
Disease Controlled Product Rate (fl oz/A) Product Instructions
Leaf and Stem Diseases
Net Blotch
(Pyrenophora teres)
Powdery Mildew
(Blumeria graminis f. sp. hordei)
Scald
(Rhynchosporium secalis)
Spot Blotch
(Bipolaris sorokiniana)
Rusts
  (Puccinia spp.)
10.3 – 13.6
(0�134 lbs
prothioconazole/A +
0�067 lbs
tebuconazole/A +
0�067 lbs fluopyram/A
to 0�177 lbs
prothioconazole/A
+ 0�089 lbs
tebuconazole/A +
0�089 lbs fluopyram/A)
Straw cut after harvest may be fed
or used for bedding�
When applied through
chemigation, large carrier volumes
may result in reduced activity
against Fusarium head blight�

Disease Suppressed Product Rate (fl oz/A) Product Instructions
Fusarium Head Blight
   (Fusarium spp.)
10.3 – 13.6
(0�134 lbs
prothioconazole/A +
0�067 lbs
tebuconazole/A +
0�067 lbs fluopyram/A
to 0�177 lbs
prothioconazole/A
+ 0�089 lbs
tebuconazole/A +
0�089 lbs fluopyram/A)
The optimal time to apply PROSARO
PRO 400 SC FUNGICIDE is as a
preventative foliar spray when barley
heads on the main stem are fully
emerged (~ Feekes Growth Stage
10�5)� Spray equipment must be set
to provide good coverage of barley
heads� For thorough coverage of the
barley head using ground application
equipment, use forward, forward
and backward mounted nozzles, or
nozzles that have a two-directional
spray� Nozzles should be operated
within the spray pressure directions
suggested by the manufacturer�
For aerial applications made prior
to heading (prior to Feekes Growth
Stage 10�5), apply a minimum of
2 gpa spray solution� For aerial
applications made at the heading
growth stage or later, apply in a
minimum of 5 gpa spray solution�
Chemigation use is allowed only for
applications made prior to heading�
Higher carrier volumes increase the
likelihood of more complete coverage
of the grain heads�
Restrictions:
• Pre-Harvest Interval (PHI): 32 days
• Do not make more than one application of PROSARO PRO 400 SC FUNGICIDE per year�
• Grazing livestock or feeding of green forage is only permitted 14 or more days after the last
application of PROSARO PRO 400 SC FUNGICIDE�
• Minimum ground application volume: 10 gallons/Acre
• For aerial applications made prior to heading (prior to Feekes Growth Stage 10�5), apply a
minimum of 2 gpa spray solution� For aerial applications made at the heading growth stage or
later, apply in a minimum of 5 gpa spray solution� Chemigation use is allowed only for applications
made prior to heading�
• Maximum PROSARO PRO 400 SC FUNGICIDE allowed per year: 13�6 fluid ounces/Acre (0�177
lbs prothioconazole, 0�089 lbs tebuconazole, 0�089 lbs fluopyram per acre)�
• Regardless of formulation or method of application, do not apply more than 0�293 lbs
prothioconazole per acre per year�
• Regardless of formulation or method of application, do not apply more than 0�113 lbs
tebuconazole per acre per year�
• Regardless of formulation or method of application, do not apply more than 0�223 lbs fluopyram
per acre per year�
• Do not make more than 2 sequential applications of a Group 7 containing product before rotating
to a fungicide from a different group�

10
CORN1
Field Corn, Field Corn Grown For Seed and Popcorn
Disease Controlled Product Rate (fl oz/A) Product Instructions
Anthracnose
   (Colletotrichum graminicola)
Eye spot
   (Aureobasidium zeae)
Gray leaf spot
   (Cercospora zeae-maydis)
Northern corn leaf blight
   (Setosphaeria turcica)*
Northern corn leaf spot
   (Cochliobolus carbonum)*
Rust
   (Puccinia spp.)
Southern corn leaf blight
   (Cochliobolus
heterostrophus)*
Tar spot
   (Phyllachora maydis)
*The above diseases are also
known as Helminthosporium
leaf blights
10.3
(0�134 lbs
prothioconazole/A
+ 0�067 lbs
tebuconazole/A +
0�067 lbs fluopyram/A)
Under some conditions, the
lowest specified labeled rate
of a spray adjuvant may be
tank-mixed with PROSARO PRO
400 SC FUNGICIDE to improve
performance�
Apply PROSARO PRO 400 SC
FUNGICIDE when disease first
appears�

Restrictions:
• Pre-Harvest Interval (PHI) for forage: 21 day(s), Do not allow livestock to graze corn forage
within 21 days of application�
• Pre-Harvest Interval (PHI) for grain or fodder: 36 day(s), Do not allow livestock to graze
corn fodder within 36 days of application�
• Minimum interval between applications: 14 days
• Minimum application volumes: 10 gallons/Acre (Ground); 2 gallons/Acre (Aerial)
• Maximum PROSARO PRO 400 SC FUNGICIDE allowed per year: 41�2 fluid ounces/Acre
(0�538 lbs prothioconazole, 0�270 lbs tebuconazole, 0�270 lbs fluopyram per acre)�
• Do not use adjuvants if PROSARO PRO 400 SC FUNGICIDE is applied between corn
growth stages V8 (8 leaf collar) and VT (lowest branch of the tassel is visible but silks have
not emerged)�
• Do not make more than 2 sequential applications of a Group 7 containing product before
rotating to a fungicide from a different group�
• Regardless of formulation or method of application, do not apply more than 0�713 lbs
prothioconazole per acre per year�
• Regardless of formulation or method of application, do not apply more than 0�675 lbs
tebuconazole per acre per year�
• Regardless of formulation or method of application, do not apply more than 0�446 lbs
fluopyram per acre per year�
1 Not for use on corn in New York�

11
WHEAT
(Spring, Durum, And Winter)
Disease Controlled Product Rate (fl oz/A) Product Instructions
Fusarium Head Blight
   (Fusarium spp.)
Leaf and Stem Diseases
Powdery Mildew
   (Blumeria graminis f. sp. tritici)
Rusts
   (Puccinia spp.)
Septoria Leaf  Blotch
   (Septoria tritici)
Stagonospora Blotch
   (Stagonospora nodorum)
Tan Spot
   (Pyrenophora tritici-repentis)
10.3 – 13.6
(0�134 lbs
prothioconazole/A
+0�067 lbs
tebuconazole/A +
0�067 lbs fluopyram/A
to 0�177 lbs
prothioconazole/A
+ 0�089 lbs
tebuconazole/A +
0�089 lbs fluopyram/A)
Straw may be fed or used for
bedding�
Fusarium Head Blight and Ergot
The optimal time to apply PROSARO
PRO 400 SC FUNGICIDE is as a
preventative foliar spray at early flower
(Feekes Growth Stage 10�51)� Spray
equipment must be set to provide
good coverage to wheat heads� For
thorough coverage of the wheat head
using ground application equipment,
use forward, forward and backward
mounted nozzles, or nozzles that
have a two-directional spray�
Operate nozzles within the spray
pressure directions suggested by the
manufacturer� When applied through
chemigation, large carrier volumes
may result in reduced activity against
Fusarium head blight and ergot�
For aerial application made prior to
early flower (prior to Feekes Growth
Stage 10�51, apply a minimum of
2 gpa spray solution� For aerial
applications made at the early flower
growth stage or later, apply in a
minimum of 5 gpa spray solution�
Chemigation use is allowed only for
applications made prior to early flower�
Higher carrier volumes increase the
likelihood of more complete coverage
of the grain heads�
Leaf and Stem Diseases
Apply PROSARO PRO 400 SC
FUNGICIDE as a preventive foliar
spray when the earliest disease
symptoms appear on the leaves
and stems� Wheat fields should be
observed closely for early disease
symptoms, particularly when
susceptible varieties are planted
and/or under prolonged conditions
favorable for disease development�
Disease Suppressed Product Rate (fl oz/A)
Ergot
(Claviceps purpurea) 10.3 – 13.6
(0�134 lbs
prothioconazole/A
+0�067 lbs
tebuconazole/A +
0�067 lbs fluopyram/A
to 0�177 lbs
prothioconazole/A
+ 0�089 lbs
tebuconazole/A +
0�089 lbs fluopyram/A)
Restrictions:
• Pre-Harvest Interval (PHI): 30 day(s)
• Minimum interval between applications: 14 days
• Do not allow livestock to graze or feed green forage to livestock prior to 14 days after treatment
with PROSARO PRO 400 SC FUNGICIDE�
• Minimum ground application volume: 10 gallons/Acre
• For aerial application made prior to early flower (prior to Feekes Growth Stage 10�51, apply a
minimum of 2 gpa spray solution� For aerial applications made at the early flower growth stage or
later, apply in a minimum of 5 gpa spray solution� Chemigation use is allowed only for applications
made prior to early flower�
• Maximum PROSARO PRO 400 SC FUNGICIDE allowed per year: 13�6 fluid ounces/Acre (0�177
lbs prothioconazole, 0�089 lbs tebuconazole, 0�089 lbs fluopyram per acre)�
• Do not make more than 2 sequential applications of a Group 7 containing product before rotating
to a fungicide from a different group�
• Regardless of formulation or method of application, do not apply more than 0� 293 lbs
prothioconazole per acre per year�
• Regardless of formulation or method of application, do not apply more than 0�113 lbs tebuconazole
per acre per year�
• Regardless of formulation or method of application, do not apply more than 0�223 lbs fluopyram
per acre per year�

12
STORAGE AND DISPOSAL
Do not contaminate water, food, or feed by storage or disposal�
Pesticide storage
Store in a cool, dry place and in such a manner as to prevent cross contamination
with other pesticides, fertilizers, food, and feed� Store in original container and out
of the reach of children, preferably in a locked storage area�
Handle and open container in a manner as to prevent spillage� If container is
leaking, invert to prevent leakage� If the container is leaking or material is spilled
for any reason or cause, carefully dam up spilled material to prevent runoff� Refer
to Precautionary Statements on label for hazards associated with the handling of
this material� Do not walk through spilled material� Absorb spilled material with
absorbing type compounds and dispose of as directed for pesticides below� In spill
or leak incidents, keep unauthorized people away�
Pesticide disposal
Wastes resulting from the use of this product may be disposed of on site or at an
approved waste disposal facility�
Container handling
Non-Refillable Containers
Rigid, Non-refillable containers (equal to or less than 5 gallons)
Non-refillable container� Do not reuse or refill this container� Triple rinse or pressure
rinse container (or equivalent) promptly after emptying� Triple rinse as follows:
Empty the remaining contents into application equipment or a mix tank and drain
for 10 seconds after the flow begins to drip� Fill the container 1/4 full with water and
recap� Shake for 10 seconds� Pour rinsate into application equipment or a mix tank
or store rinsate for later use or disposal� Drain for 10 seconds after the flow begins
to drip� Repeat this procedure two more times�
Pressure rinse as follows: Empty the remaining contents into application equipment
or a mix tank and continue to drain for 10 seconds after the flow begins to drip� Hold
container upside down over application equipment or mix tank or collect rinsate for
later use or disposal� Insert pressure rinsing nozzle in the side of the container, and
rinse at about 40 PSI for at least 30 seconds� Drain for 10 seconds after the flow
begins to drip�
Once container is rinsed, offer for recycling if available or puncture and dispose of
in a sanitary landfill or by incineration�

13

14

15

US87306429A            210819A  09/21
US87306429A (210819A) PROSARO PRO 400 SC 2.5G BASE LABEL
COLORS: CMYK     DATE: 09/07/21
Label Coordinator:  Mark Schmidt
PROTHIOCONAZOLE GROUP
GROUP
GROUP
3
3
7
FUNGICIDE
FUNGICIDE
FUNGICIDE
TEBUCONAZOLE
FLUOPYRAM
FIRST AID
IF SWALLOWED: • Call a poison control center or
doctor immediately for treatment
advice�
• Do not induce vomiting unless
told to do so by a poison control
center or doctor�
• Have person sip a glass of
water if able to swallow�
• Do not give anything by mouth
to an unconscious person�
IF ON SKIN OR
CLOTHING:
• Take off contaminated clothing�
• Rinse skin immediately with
plenty of water for 15-20 minutes�
• Call a poison control center or
doctor for treatment advice�
IF IN EYES: • Hold eye open and rinse slowly
and gently with water for 15-20
minutes�
• Remove contact lenses, if
present, after the first 5 minutes,
then continue rinsing eye�
• Call a poison control center or
doctor for treatment advice�
IF INHALED: • Move person to fresh air�
• If person is not breathing, call 911
or an ambulance, and then give
artificial respiration, preferably
mouth-to-mouth if possible�
• Call a poison control center or
doctor for treatment advice�
For MEDICAL Emergencies Call 24 Hours A Day
1-800-334-7577.
Have the product container or label with you
when calling a poison control center or doctor
or going for treatment.
NOTE TO PHYSICIAN: No specific antidote� Treat
symptomatically�
PRECAUTIONARY STATEMENTS
HAZARDS TO HUMANS AND DOMESTIC ANIMALS
CAUTION
Harmful if swallowed, inhaled, or absorbed through the
skin� Causes moderate eye irritation� Avoid contact
with skin, eyes, and clothing� Avoid breathing vapor or
spray mist� Wash thoroughly with soap and water after
handling and before eating, drinking, chewing gum, or
using tobacco, or using the toilet� Remove and wash
contaminated clothing before reuse�
PROSARO® PRO 400 SC Fungicide
For control of specific diseases on listed crops.
Active Ingredients:
Prothioconazole, 2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]
-1,2-dihydro-3H-1,2,4-triazole-3-thione ������������������������������������������������������������������������������������������������������17.39%
Tebuconazole, alpha-[2-(4-chlorophenyl)ethyl]-alpha-(1,1-dimethylethyl)-
1H-1,2,4-triazole-1-ethanol ���������������������������������������������������������������������������������������������������������������������������8.70%
Fluopyram, N-[2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl]-2
(trifluoromethyl)benzamide ���������������������������������������������������������������������������������������������������������������������������8.70%
Other Ingredients:  �����������������������������������������������������������������������������������������������������������������������������������65.21%
TOTAL:  100.0%
Contains 1�67 pounds of prothioconazole, 0�84 pounds of tebuconazole,
and 0�84 pounds of fluopyram per U�S� gallon
EPA Reg. No. 264-1209
KEEP OUT OF REACH OF CHILDREN
CAUTION
For MEDICAL and TRANSPORTATION Emergencies ONLY Call 24 Hours A Day 1-800-334-7577
For PRODUCT USE Information Call 1-866-99BAYER (1-866-992-2937)
See Back Panel for First Aid Instructions and Booklet for Complete
Precautionary Statements and Directions for Use.
DIRECTIONS FOR USE
It is a violation of federal law to use this product
in a manner inconsistent with its labeling.
STORAGE AND DISPOSAL
Do not contaminate water, food, or feed by storage or
disposal�
Pesticide storage: Store in a cool, dry place and in
such a manner as to prevent cross contamination
with other pesticides, fertilizers, food, and feed� Store
in original container and out of the reach of children,
preferably in a locked storage area�
Handle and open container in a manner as to prevent
spillage� If container is leaking, invert to prevent leakage�
If the container is leaking or material is spilled for any
reason or cause, carefully dam up spilled material to
prevent runoff� Refer to Precautionary Statements on
label for hazards associated with the handling of this
material� Do not walk through spilled material� Absorb
spilled material with absorbing type compounds and
dispose of as directed for pesticides below� In spill or
leak incidents, keep unauthorized people away�
Pesticide disposal: Wastes resulting from the use
of this product may be disposed of on site or at an
approved waste disposal facility�
Container handling: Non-Refillable Containers
Rigid, Non-refillable containers (equal to or less
than 5 gallons)
Non-refillable container� Do not reuse or refill this
container� Triple rinse or pressure rinse container (or
equivalent) promptly after emptying� Triple rinse as
follows:  Empty the remaining contents into application
equipment or a mix tank and drain for 10 seconds after
the flow begins to drip� Fill the container 1/4 full with
water and recap� Shake for 10 seconds� Pour rinsate into
application equipment or a mix tank or store rinsate for
later use or disposal� Drain for 10 seconds after the flow
begins to drip� Repeat this procedure two more times�
Pressure rinse as follows: Empty the remaining contents
into application equipment or a mix tank and continue to
drain for 10 seconds after the flow begins to drip� Hold
container upside down over application equipment or
mix tank or collect rinsate for later use or disposal� Insert
pressure rinsing nozzle in the side of the container, and
rinse at about 40 PSI for at least 30 seconds� Drain for
10 seconds after the flow begins to drip�
Once container is rinsed, offer for recycling if available or
puncture and dispose of in a sanitary landfill or by incineration�
Bayer CropScience LP
800 N� Lindbergh Blvd�
St� Louis, MO 63167
©2021 Bayer Group
NET CONTENTS: 2 1/2 GALLONS