crop-chem-docs/corpus/epa_ppls/100-1145.md

# Mefenoxam 2E

- EPA Reg No: **100-1145**
- Registrant: SYNGENTA CROP PROTECTION, LLC
- Signal word: Warning
- Active ingredients: Metalaxyl-M (25.1%)
- Label accepted: 2023-06-21
- Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000100-01145-20230621.pdf

---
UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 
 WASHINGTON, DC 20460 
OFFICE OF CHEMICAL SAFETY 
AND POLLUTION PREVENTION 
New Use PRIA Unconditional v.20220527 
 
June 21, 2023 
 
Nestor Algarin 
Regulatory Product Manager 
Syngenta Crop Protection, LLC 
P.O. Box 18300 
Greensboro, NC 27419 
 
Subject: PRIA Label Amendment – Mefenoxam: Crop group conversions/revisions for 
Cottonseed, subgroup 20C; Leaf petiole subgroup 22B; Leafy vegetable, Crop 
Group 4-16 (except spinach); Vegetable, Brassica, head and stem, group 5-16; 
Vegetable, fruiting, group 8-10; Vegetable, legume, bean, succulent shelled, 
subgroup 6-22C; Vegetable, legume, pea, succulent shelled, subgroup 6-22D; 
Vegetable, stalk and stem, subgroup 22A; Plant back Interval – 30 days for 
sugarcane 
 
 Product Name: Mefenoxam 2E 
 EPA Registration Number: 100-1145 
 Application Dates: 11/23/2021, 11/24/2021 
 Petition Numbers: 1F8970, 1F8971 
 Decision Numbers: 580474, 580481, 580471, 580479 
 
Dear Nestor Algarin: 
 
The application referred to above, submitted under the Federal Insecticide, Fungicide, and 
Rodenticide Act (FIFRA), as amended, is acceptable under FIFRA section 3(c)(5). 
 
You must submit and/or cite all data required for registration/reregistration/registration review of 
your product when the Agency requires all registrants of similar products to submit such data. 
 
A stamped copy of your labeling is enclosed for your records. This labeling supersedes all 
previously accepted labeling. You must submit one (1) copy of the final printed labeling before 
you release the product for shipment with the new labeling. In accordance with 40 CFR 
152.130(c), you may distribute or sell this product under the previously approved labeling for 18 
months from the date of this letter. After 18 months, you may only distribute or sell this product 
if it bears this new revised labeling or subsequently approved labeling. “To distribute or sell” is 
defined under FIFRA section 2(gg) and its implementing regulation at 40 CFR 152.3. 
 
Should you wish to add/retain a reference to the company’s website on your label, then please be 
aware that the website becomes labeling under FIFRA and is subject to review by the Agency. If 
the website is false or misleading, the product would be misbranded and unlawful to sell or

Page 2 of 2 
EPA Reg. No. 100-1145 
Decision No. 580474, 580481, 580471, 580479 
 
distribute under FIFRA section 12(a)(1)(E). 40 CFR 156.10(a)(5) lists examples of statements 
EPA may consider false or misleading. In addition, regardless of whether a website is referenced 
on your product’s label, claims made on the website may not substantially differ from those 
claims approved through the registration process. Therefore, should the Agency find or if it is 
brought to our attention that a website contains false or misleading statements or claims 
substantially differing from the EPA approved registration, the website will be referred to the 
EPA’s Office of Enforcement and Compliance. 
 
Your release for shipment of the product constitutes acceptance of these conditions. If these 
conditions are not complied with, the registration will be subject to cancellation in accordance 
with FIFRA section 6. 
 
If you have any questions, please contact Stephanie Suarez at 202-566-2918 or at 
Suarez.Stephanie@epa.gov. 
 
 
 S i n c e r e l y , 
 
 C y n t h i a G i l e s - P a r k e r , C h i e f 
 Fungicide Branch 
 Registration Division (7505T) 
 
 
Enclosure – stamped “accepted” label

Mefenoxam 2E 
 
FUNGICIDE 
 
For the control of certain diseases in listed crops caused by Oomycetes 
 
Active Ingredient: 
Mefenoxam* ........................................................................................................................ 25.1% 
Other Ingredients: 74.9% 
Total: 100.0% 
 
 *CAS No. 70630-17-0 and 69516-34-3 
 
Contains petroleum distillate 
 
Mefenoxam 2E is formulated as a soluble concentrate and contains 2.0 lb active ingredient 
per gallon. 
 
 
KEEP OUT OF REACH OF CHILDREN. 
 
WARNING/AVISO 
 
Si usted no entiende la etiqueta, busque a alguien para que se la explique a usted en detalle. 
(If you do not understand the label, find someone to explain it to you in detail.) 
 
See additional Precautionary Statements and Directions for Use inside booklet. 
 
EPA Reg. No. 100-1145 
EPA Est. 
 
__________ 
Net Contents 
 
[Batch Code: _____] (For nonrefillables only.) 
MEFENOXAM GROUP 4 FUNGICIDE 
06/21/2023
100-1145

TABLE OF CONTENTS 
 
1.0 FIRST AID 
2.0 PRECAUTIONARY STATEMENTS 
2.1 Hazards to Humans and Domestic Animals 
2.2 Personal Protective Equipment (PPE) 
2.2.1 USER SAFETY REQUIREMENTS 
2.2.2 ENGINEERING CONTROLS 
2.2.3 USER SAFETY RECOMMENDATIONS 
2.3 Environmental Hazards 
2.3.1 GROUNDWATER ADVISORY 
2.4 Physical or Chemical Hazards 
DIRECTIONS FOR USE 
3.0 PRODUCT INFORMATION 
3.1 Integrated Pest Management (IPM) 
3.2 Resistance Management 
4.0 APPLICATION DIRECTIONS 
4.1 Methods of Application 
4.1.1 BAND APPLICATION 
4.1.2 IN-FURROW APPLICATION 
4.2 Application Equipment 
4.2.1 NOZZLES 
4.2.2 PUMP 
4.3 Application Volume and Spray Coverage 
4.4 Mixing Directions 
4.4.1 MEFENOXAM 2E ALONE 
4.4.2 TANK-MIX PRECAUTIONS 
4.4.3 TANK-MIX COMPATIBILITY TEST 
4.4.4 MEFENOXAM 2E IN TANK MIXTURES 
4.5 Application through Irrigation Systems (Chemigation) 
4.5.1 CHEMIGATION RESTRICTIONS 
4.5.2 OPERATING INSTRUCTIONS FOR PUBLIC WATER SYSTEMS 
4.5.3 SPECIFIC INSTRUCTIONS FOR PUBLIC WATER SYSTEMS 
4.5.4 APPLICATION DIRECTIONS FOR IRRIGATION SYSTEMS 
5.0 REPLANT AND ROTATIONAL CROP RESTRICTIONS 
5.1 Replanting 
5.2 Rotational Crop Restrictions 
6.0 RESTRICTIONS AND PRECAUTIONS 
6.1 Use Restrictions 
6.2 Use Precautions 
6.3 Spray Drift Management 
6.4 Spray Drift Advisory 
6.4.1 IMPORTANCE OF DROPLET SIZE

6.4.2 CONTROLLING DROPLET SIZE – GROUND BOOM 
6.4.3 CONTROLLING DROPLET SIZE – AIRCRAFT 
6.4.4 BOOM HEIGHT – GROUND BOOM 
6.4.5 RELEASE HEIGHT - AIRCRAFT 
6.4.6 SHIELDED SPRAYERS 
6.4.7 TEMPERATURE AND HUMIDITY 
6.4.8 TEMPERATURE INVERSIONS 
6.4.9 WIND 
7.0 CROP USE DIRECTIONS 
7.1 Alfalfa 
7.2 Apple 
7.3 Artichoke 
7.4 Avocado 
7.5 Berry and Small Fruit 
7.5.1 BUSHBERRY, CROP SUBGROUP 13-07B 
7.5.2 CANEBERRY, CROP SUBGROUP 13-07A 
7.5.3 CRANBERRY 
7.5.4 SMALL FRUIT VINE CLIMBING (EXCEPT GRAPE), CROP SUBGROUP 13-07E 
7.5.5 STRAWBERRY 
7.6 Brassica Head and Stem Vegetables, Crop Group 5-16 
7.7 Brassica Leafy Greens, Crop Subgroup 4-16B 
7.8 Bulb Vegetables, Crop Group 3-07 
7.9 Cacao 
7.10 Citrus Fruit, Crop Group 10 
7.11 Clover 
7.12 Cotton, Crop Subgroup 20C 
7.13 Cucurbit Vegetables, Crop Group 9 
7.14 Fruiting Vegetables, Crop Group 8-10 
7.15 Grapes 
7.16 Grass Forage, Fodder, and Hay, Crop Group 17 
7.17 Herbs (fresh and dried), Crop Subgroup 19A 
7.18 Hops 
7.19 Leafy Greens, Crop Subgroup 4-16A 
7.20 Spinach 
7.21 Legume Vegetables, Crop Group 6-22 
7.22 Succulent Shelled Beans, Crop Subgroup 6-22C 
7.23 Succulent Shelled Peas, Crop Subgroup 6-22D 
7.24 Peanut 
7.25 Pineapple, Crown Dip 
7.26 Root and Tuber Vegetables 
7.26.1 CARROT 
7.26.2 GINSENG 
7.26.3 POTATO 
7.26.4 ROOT AND TUBER VEGETABLES, CROP GROUP 1 (EXCEPT CARROT, GINSENG, 
AND POTATO)

7.27 Soybean 
7.28 Celtuce 
7.29 Fennel 
7.30 Kohlrabi 
7.31 Leaf Petiole Vegetables, Crop Subgroup 22B 
7.32 Stalk and Stem Vegetables, Crop Subgroup 22A 
7.33 Stone Fruits, Crop Group 12 
7.34 Tobacco 
7.35 Tree Nuts, Crop Group 14-12 
7.36 Tropical and Subtropical Fruit 
7.36.1 MEDIUM TO LARGE FRUIT, SMOOTH PEEL 
7.36.2 MEDIUM TO LARGE FRUIT, ROUGH OR HAIRY PEEL 
7.37 Wasabi 
8.0 STORAGE AND DISPOSAL 
9.0 CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY 
10.0 APPENDIX 
10.1 [Optional] Mefenoxam 2E Use Summary Table

1 
1.0 FIRST AID 
 
FIRST AID 
If in eyes  Hold eye open and rinse slowly and gently with water for 15-20 
minutes. 
 Remove contact lenses, if present, after the first 5 minutes, then 
continue rinsing eye. 
 Call a poison control center or doctor for treatment advice. 
If on skin or 
clothing 
 Take off contaminated clothing. 
 Rinse skin immediately with plenty of water for 15-20 minutes. 
 Call a poison control center or doctor for treatment advice. 
If swallowed  Call a poison control center or doctor immediately for treatment 
advice. 
 DO NOT give any liquid to the person. 
 DO NOT induce vomiting unless told to do so by the poison 
control center or doctor. 
 DO NOT give anything by mouth to an unconscious person. 
If inhaled  Move person to fresh air. 
 If person is not breathing, call 911 or an ambulance, then give 
artificial respiration, preferably by mouth-to-mouth, if possible. 
 Call a poison control center or doctor fo r treatment advice. 
NOTE TO PHYSICIAN 
Contains petroleum distillate – vomiting may cause aspiration pneumonia. Treat 
symptomatically. 
Have the product container or label with you when calling a poison control center or 
doctor, or going for treatment. 
HOTLINE NUMBER 
For 24-Hour Medical Emergency Assistance (Human or Animal) 
or Chemical Emergency Assistance (Spill, Leak, Fire, or Accident) 
Call 
1-800-888-8372 
 
2.0 PRECAUTIONARY STATEMENTS 
2.1 Hazards to Humans and Domestic Animals 
WARNING/AVISO 
 
Causes substantial but temporary eye injury. DO NOT get in eyes. Wear safety glasses, 
goggles, or a face shield. Wash thoroughly with soap and water after handling and before 
eating, drinking, chewing gum, using tobacco, or using the toilet. Harmful if swallowed or 
absorbed through skin. Avoid contact with skin or clothing. Remove contaminated clothing 
and wash before reuse.

2 
 
 
2.2 Personal Protective Equipment (PPE) 
Applicators and other handlers must wear: 
 Protective eyewear 
 Long-sleeved shirt and long pants 
 Chemical-resistant gloves made of barrier laminate, butyl rubber ≥ 14 mils, nitrile 
rubber ≥ 14 mils, neoprene rubber ≥ 14 mils, polyvinyl chloride (PVC) ≥ 14 mils, or 
Viton™ ≥ 14 mils 
 Shoes plus socks 
 
2.2.1 USER SAFETY REQUIREMENTS 
Discard clothing and other absorbent materials that have been drenched or heavily 
contaminated with this product’s concentrate. DO NOT reuse them. Follow manufacturer’s 
instructions for cleaning/maintaining PPE. If no such instructions for washables exist, use 
detergent and hot water. Keep and wash PPE separately from other laundry. 
2.2.2 ENGINEERING CONTROLS 
When handlers use closed systems, enclosed cabs, or aircraft in a manner that meets the 
requirements listed in the Worker Protection Standard (WPS) for agricultural pesticides (40 
CFR 170.240(d)(4-6)), the handler PPE requirements may be reduced or modified as 
specified in the WPS. 
 
2.2.3 USER SAFETY RECOMMENDATIONS 
User Safety Recommendations 
Users should: 
 Remove clothing/PPE immediately if pesti cide gets inside. Then wash thoroughly 
and put on clean clothing. 
 Remove PPE immediately after handling th is product. Wash the outside of gloves 
before removing. As soon as possible, wash thoroughly and change into clean 
clothing. 
 
2.3 Environmental Hazards 
DO NOT apply directly to water, to areas where surface water is present, or to intertidal areas 
below the mean high-water mark. DO NOT contaminate water when disposing of equipment 
washwater or rinsate.

3 
 
2.3.1 GROUNDWATER ADVISORY 
Mefenoxam is known to leach through soil into groundwater under certain conditions as a 
result of label use. This chemical may leach into groundwater if used in areas where soils 
are permeable, particularly where the water table is shallow. 
2.4 Physical or Chemical Hazards 
DO NOT use or store near heat or open flame. 
 
DIRECTIONS FOR USE 
It is a violation of federal law to use this product in a manner inconsistent with its labeling. 
 
DO NOT apply this product in a way that will contact workers or other persons, either directly 
or through drift. Only protected handlers may be in the area during application. For any 
requirements specific to your state or tribe, consult the agency responsible for pesticide 
regulation. 
 
FAILURE TO FOLLOW DIRECTIONS AND PRECAUTIONS ON THIS LABEL MAY 
RESULT IN CROP INJURY, POOR DISEASE CONTROL, OR ILLEGAL RESIDUES. 
 
AGRICULTURAL USE REQUIREMENTS 
Use this product only in accordance with its labeling and with the Worker Protection 
Standard, 40 CFR Part 170. This Standard contains requirements for the protection of 
agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of 
agricultural pesticides. It contains requirements for training, decontamination, notification, 
and emergency assistance. It also contains specific instructions and exceptions pertaining 
to the statements on this label about personal protective equipment (PPE), restricted-entry 
interval, and notification to workers (as applicable). The requirements in this box only apply 
to uses of this product that are covered by the Worker Protection Standard (WPS). 
 
DO NOT enter or allow worker entry into treated areas during the restricted-entry 
interval (REI) of 48 hours. 
 
Exception: If the product is soil-injected or soil-incorporated, the Worker Protection 
Standard, under certain circumstances, allows workers to enter the treated area 
immediately if there will be no contact with anything that has been treated.

4 
PPE required for early entry to treated areas that is permitted under the Worker Protection 
Standard and that involves contact with anything that has been treated, including plants, 
soil, or water, is: 
 Protective eyewear 
 Coveralls 
 Chemical-resistant gloves made of barrier laminate, butyl rubber ≥ 14 mils, nitrile rubber 
≥ 14 mils, neoprene rubber ≥ 14 mils, polyvinyl chloride (PVC) ≥ 14 mils, or Viton ≥ 14 
mils 
 Shoes plus socks 
 
 
3.0 PRODUCT INFORMATION 
Mefenoxam 2E is a systemic fungicide for use on selected crops to control certain diseases 
caused by Oomycetes. 
 
 
To ensure maximum activity on soilborne pathogens, Mefenoxam 2E must be moved into the 
seed or root zone of the plant. Placement in the seed or root zone includes in-furrow sprays, 
soil injections, and crown dips. Incorporation includes preplant incorporated applications, soil 
drenches, or shank applications. 
 
For soil surface sprays, rainfall will move the fungicide into the seed or root zone, but if rain is 
not expected within 24 hours after application, mechanically incorporate (before planting) or 
sprinkler irrigate (after planting) with ½ to 1 inch of water. 
 
Under conditions conducive to severe disease pressure, additional fungicide applications 
may be applied using an alternate fungicide registered for the crop/disease appearing on this 
label. 
 
Where rate ranges are specified on this label, use the higher specified rate when heavy 
disease pressure is expected and the lower specified rate when disease pressure is expected 
to be light, unless otherwise noted. 
 
EFFICACY 
Under certain conditions conducive to extended infection periods, use another registered 
fungicide for additional applications if maximum amount of Mefenoxam 2E has been used. If 
resistant isolates to Group 4 fungicides are present, efficacy can be reduced. Under high 
disease pressure, use the highest specified rate and shortest specified interval when needed. 
 
CROP TOLERANCE 
Plant tolerance has been found acceptable for all crops on the label; however, not all possible 
tank-mix combinations have been tested under all conditions. When possible, test the 
combinations on a small portion of the crop to ensure a phytotoxic response will not occur as 
a result of application.

5 
3.1 Integrated Pest Management (IPM) 
Integrate Mefenoxam 2E into an overall disease and pest management strategy (IPM) 
whenever the use of a fungicide is required. Follow cultural practices known to reduce 
disease development. Consult your local agricultural authorities for additional IPM strategies 
established for your area. 
 
3.2 Resistance Management 
 
 
For resistance management, Mefenoxam 2E contains a Group 4 fungicide. Any fungal 
population may contain individuals naturally resistant to Mefenoxam 2E and other Group 4 
fungicides. A gradual or total loss of pest control may occur over time if these fungicides are 
used repeatedly in the same fields. Appropriate resistance-management strategies must be 
followed. 
To delay fungicide resistance, take one or more of the following steps: 
 Rotate the use of Mefenoxam 2E or other Group 4 fungicides within a growing season 
sequence with different groups that control the same pathogens. 
 Use tank mixtures with fungicide from a di fferent group that are equally effective on the 
target pest when such use is permitted. Use at least the minimum application rate as 
labeled by the manufacturer. 
 Adopt an integrated diseas e management program for fungicide use that includes 
scouting, uses historical information related to pesticide use and crop rotation, and which 
considers host plant resistance, impact of environmental conditions on disease 
development, disease thresholds, as well as cultural, biological and other chemical control 
practices. 
 Where possible, make use of predictive di sease models to effectively time fungicide 
applications. Note that using predictive models alone is not sufficient to manage 
resistance. 
 Monitor treated fungal populati ons for resistance development. 
 Contact your local extension specialist or ce rtified crop advisor for any additional pesticide 
resistance-management and/or IPM guidance for specific crops and pathogens. 
 For further information or to report suspected resistance, contact Syngenta at 1-866-
Syngent(a) (866-796-4368). You can also contact your pesticide distributor or university 
extension specialist to report resistance. 
 
4.0 APPLICATION DIRECTIONS 
4.1 Methods of Application

6 
Applications with Mefenoxam 2E are permitted by ground, by air, and via chemigation as 
specified in Section 7.0 unless otherwise restricted in Section 6.1. Ground application 
includes broadcast sprays, soil incorporation, banded and in-furrow applications, as well as 
soil injections and crown dips. Incorporation includes preplant incorporated, soil drenches, 
and shank applications. 
 
For band applications, refer to Section 4.1.1 to calculate the amount of Mefenoxam 2E and 
water volume needed. For in-furrow applications, refer to Section 4.1.2 for the amount of 
product to use with common row spacings. Refer to Section 4.5 for details of application by 
chemigation. 
 
4.1.1 BAND APPLICATION 
Application rates in Section 7.0 are expressed as an amount per acre which refers to the 
total crop area to be treated. If rates are expressed as amount per acre and banded 
applications are used, then the correct amount of pesticide used per acre will be 
proportionately less because the area to be treated is actually the area covered by the band, 
not the total cropland planted. Use the following formula to calculate the amount of 
Mefenoxam 2E needed per acre of crop when banded applications are made. 
 
band width in inches X broadcast rate = amount needed 
row spacing in inches per acre per acre of field 
 
4.1.2 IN-FURROW APPLICATION 
 The following table provides common row spacing and the amount of Mefenoxam 2E to 
apply per acre for applications in Cotton, Peanut, Potato, and Soybean ONLY. 
 
Use Rate 
fl oz/1,000 row 
feet 
(oz ai/1,000 row 
feet) 
 Mefenoxam 2E 
fl oz/A 
20 
inch 
rows 
22 
inch 
rows 
24 
inch 
rows 
30 
inch 
rows 
32 
inch 
rows 
34 
inch 
rows 
36 
inch 
rows 
38 
inch 
rows 
40 
inch 
rows 
0.15 
(0.038) 
4.0 3.6 3.2 2.6 2.5 2.3 2.2 2.1 2.0 
0.3 
(0.075) 
7.8 7.0 6.5 5.2 5.0 4.6 4.3 4.1 4.0 
0.56 
(0.14) 
14.5 13.3 12.2 9.8 9.1 8.5 8.1 7.7 7.3

7 
0.84 
(0.21) 
22.0 20.0 18.3 14.5 13.7 13.0 12.2 11.6 11.0 
20” = 26,136 row ft/A, 22" = 23,760 row ft/A, 24” = 21,780 row ft/A, 30" = 17,424 row ft/A, 32" = 
16,315 row ft/A, 34" = 15,374 row ft/A, 36" = 14,520 row ft/A, 38" = 13,754 row ft/A, 40" = 
13,068 row ft/A 
 
 
4.2 Application Equipment 
 Arrange spray equipment configuration to pr ovide accurate application and minimize the 
potential for spray drift. 
 To ensure accuracy, calibrate sprayer before each use. 
 For information on spray equipment and calibration, consult spray equipment 
manufacturers and/or state guidance. 
 All ground/aerial/chemigation application equipment must be properly maintained and 
calibrated using appropriate carriers. 
 
4.2.1 NOZZLES 
 Equip sprayers with nozzles that provide accurate and uniform application. 
 Use same size nozzles and uniform spacing across the boom. 
 Use screens to protect the pump and to prevent nozzles from clogging. 
 Screens placed on suction side of pump must be 16-mesh or coarser. 
 DO NOT place a screen in the recirculation line. 
 Use 50-mesh or coarser screens between the pump and boom, and where required, at 
the nozzles. 
 Check nozzle manufacturer’s specifications. 
 
 
4.2.2 PUMP 
 Use a pump with capacity to: 
o Maintain 35-40 psi at nozzles. 
o Provide sufficient agitation in tank to keep mixture in suspension - this requires 
recirculation of 10% of tank volume per minute. 
 Use a jet agitator or liquid sparger tube for agitation. 
 DO NOT air sparge. 
 
For more information on spray equipment and calibration, consult sprayer manufacturers and 
state guidance. For specific local directions and spray schedules, consult the current state 
agricultural guidance.

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4.3 Application Volume and Spray Coverage 
 
 Apply by ground or air in sufficient water or li quid fertilizer to provide uniform coverage of 
the soil surface. 
 For maximum effectiveness, Mefenoxam 2E must be moved into the seed or root zone of 
the plant. 
 For in-furrow application, apply as an in-furrow spray in 3-7 gallons of water per acre at 
planting. Mount the spray nozzle so the spray is directed into the furrow just before the 
seed is covered. 
 For ground broadcast application, apply in a mi nimum of 20 gallons of water per acre, 
unless specified otherwise. If rain is not expected within 24 hours after application, 
mechanically incorporate (before planting) or sprinkler irrigate (after planting) with ½ to 1 
inch of water. 
 For aerial application, apply in a minimum of 3 gallons of water per acre, unless specified 
otherwise. Avoid application when uniform coverage cannot be obtained or when 
excessive spray drift may occur. 
 
 
 
4.4 Mixing Directions 
1. Thoroughly clean spray equipment before using this product. 
2. Prepare no more spray mixture than is needed for the immediate operation. 
3. Keep product container tight ly closed when not in use. 
4. Agitate the spray solution before and during application. 
5. DO NOT let the spray mixture stand overnight in the spray tank. 
6. Rinse the spray equipment thoroughly a fter each day’s use and dispose of pesticide 
rinsate by application to an already treated area. 
 
4.4.1 MEFENOXAM 2E ALONE 
1. Add ¼ - ½ of the requi red amount of water to the spray or mixing tank. 
2. With the agitator running, add Mefenoxam 2E to the tank. 
3. Continue agitation while adding the remainder of the water. 
4. Begin application of the spray solution after Mefenoxam 2E has completely dispersed into 
the mix water. 
5. Maintain agitation until all of the mixture has been sprayed. 
 
4.4.2 TANK-MIX PRECAUTIONS 
 It is the pesticide user’s responsibility to ens ure that all products are registered for their 
intended use. Read and follow the applicable restrictions and limitations and directions for 
use on all product labels involved in tank mixing. Users must follow the most restrictive 
directions for use and precautionary statements for each product in the tank mixture. 
 Tank mixes of Mefenoxam 2E with other pestici des, fertilizers, or any other additives not 
specifically labeled for use with Mefenoxam 2E may result in tank-mix incompatibility or 
unsatisfactory performance. In such cases, always check tank-mix compatibility by 
conducting a jar test according to guidance in Section 4.4.3 before actual tank mixing.

9 
 
4.4.3 TANK-MIX COMPATIBILITY TEST 
 Conduct a jar test using a 1 pt to 1 qt cont ainer with lid by adding water or other intended 
carrier (e.g., a liquid fertilizer) to the jar. 
 Next, add the appropriate amount of pesticide(s) or tank-mix partner(s) in their relative 
proportions based on specified label rates. Add tank-mix components separately in the 
order described in Section 4.4.4. After each addition, shake or stir gently to thoroughly 
mix. 
 After all ingredients have been added, put the lid on the jar, tighten and invert the jar 10 
times to mix. 
 After mixing, let the mixture stand 15 – 30 minutes and then examine for signs of 
incompatibility including obvious separation, large flakes, precipitates, gels, or heavy oily 
film on the jar. 
 If the mixture remains mixed or can be remixed readily, it is physically compatible and can 
be used. 
 If the mixture is incompatible , repeat the test using a compatibility agent at the directed 
rate. Or, if applicable, slurry dry formulations in water before adding to the jar. If 
incompatibility is still observed after following these procedures, DO NOT use the mixture. 
 After compatibility testing is complete, dispose of any pesticide wastes in accordance with 
Section 8.0. 
 
4.4.4 MEFENOXAM 2E IN TANK MIXTURES 
1. Add ¼ - ½ of the requi red amount of water to the spray or mixing tank. 
2. With the agitator running, add the tank-mix pa rtner(s) into the tank in the following order: 
a. wettable powders 
b. water dispersible granular products 
c. liquid flowables 
d. emulsifiable concentrates 
3. Allow the material to completely di ssolve and disperse into the mix water. 
4. Continue agitation while adding the remain der of the water and Mefenoxam 2E to the 
spray tank. 
5. Allow Mefenoxam 2E to completely disperse. 
6. Spray the mixture with the agitator running. 
7. Follow the precautions and limit ations of the most restricted product in the tank mixture. 
 
 
4.5 Application through Irrigation Systems (Chemigation) 
4.5.1 CHEMIGATION RESTRICTIONS 
 Use only on crops for which chemigat ion is specified on this label. 
 Apply Mefenoxam 2E only through center pivot, solid set, hand move, moving wheel, 
micro-sprinkler, micro-emitter, or drip irrigation systems. DO NOT apply this product 
through any other type of irrigation system.

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 Crop injury, lack of effectiveness, or illegal pe sticide residues in the crop can result from 
non-uniform distribution of treated water. 
 If you have questions about calibration, contact your State Extension Service specialists, 
equipment manufacturers, or other experts. 
 DO NOT connect an irrigation system (including greenhouse systems) used for pesticide 
application to a public water system unless the pesticide label-prescribed safety devices 
for public water systems are in place. 
 A person knowledgeable of the chemigation system and responsible for its operation, or 
under the supervision of the responsible person, shall shut the system down and make 
necessary adjustments if the need arises. 
 Mefenoxam 2E must be applied on the schedul e specified in the specific crop use 
directions, not according to the irrigation schedule. 
 
Note: Mefenoxam 2E can affect many seal materials and must not be used at full strength. 
Leather seals are best; EPDM or silicone rubber seals can be used, but must be checked and 
replaced once a year if needed. DO NOT use Viton, Buna-N, Neoprene, or PVC seals. 
 
4.5.2 OPERATING INSTRUCTIONS FOR PUBLIC WATER SYSTEMS 
1. The system must contain a functional check va lve, vacuum relief valve, and low pressure 
drain appropriately located on the irrigation pipeline to prevent water-source 
contamination from backflow. 
2. The pesticide injection pipeline must contai n a functional, automatic, quick-closing check 
valve to prevent the flow of fluid back toward the injection pump. 
3. The pesticide injection pipeline must also contain a functional, normally closed, solenoid-
operated valve located on the intake side of the injection pump and connected to the 
system interlock to prevent fluid from being withdrawn from the supply tank when the 
irrigation system is either automatically or manually shut down. 
4. The system must contain functional interlo cking controls to automatically shut off the 
pesticide injection pump when the water pump motor stops. 
5. The irrigation line or water pump must include a functional pressure switch which will stop 
the water pump motor when the water pressure decreases to the point where pesticide 
distribution is adversely affected. 
6. Systems must use a metering pump, includ ing a positive displacement injection pump 
(e.g., diaphragm pump), effectively designed and constructed of materials that are 
compatible with pesticides and capable of being fitted with a system interlock. 
7. DO NOT apply when wind speed favors drift beyond the area intended for treatment. 
 
 
4.5.3 SPECIFIC INSTRUCTIONS FOR PUBLIC WATER SYSTEMS 
 
1. Public water system means a system for t he provision to the public of piped water for 
human consumption if such system has at least 15 service connections or regularly 
serves an average of at least 25 individuals daily at least 60 days out of the year. 
2. Chemigation systems connect ed to public water systems must contain a functional, 
reduced-pressure zone (RPZ) backflow preventer or the functional equivalent in the 
water supply line upstream from the point of pesticide introduction. As an option to the

11 
RPZ, the water from the public water system must be discharged into a reservoir tank 
prior to pesticide introduction. There shall be a complete physical break (air gap) 
between the outlet end of the fill pipe and the top or overflow rim of the reservoir tank of 
at least twice the inside diameter of the fill pipe. 
3. The pesticide injection pipeline must cont ain a functional, automatic, quick-closing check 
valve to prevent the flow of fluid back toward the injection pump. 
4. The pesticide injection pipeline must c ontain a functional, normally closed, solenoid-
operated valve located on the intake side of the injection pump and connected to the 
system interlock to prevent fluid from being withdrawn from the supply tank when the 
irrigation system is either automatically or manually shut down. 
5. The system must contain functional interlo cking controls to automatically shut off the 
pesticide injection pump when the water pump motor stops, or, in cases where there is 
no water pump, when the water pressure decreases to the point where pesticide 
distribution is adversely affected. 
6. Systems must use a metering device, includ ing a positive displacement injection pump 
(e.g., diaphragm pump), effectively designed and constructed of materials that are 
compatible with pesticides and capable of being fitted with a system interlock. 
7. DO NOT apply when wind speed favors drift beyond the area intended for treatment. 
 
4.5.4 APPLICATION DIRECTIONS FOR IRRIGATION SYSTEMS 
 Apply Mefenoxam 2E only through center pivot, solid set, hand move, moving wheel, 
micro-sprinkler, micro-emitter, or drip irrigation systems. DO NOT apply this product 
through any other type of irrigation system. 
 DO NOT inject Mefenoxam 2E at full strength or deterioration of seals may occur. Use a 
dilution ratio of at least 15 parts water to 1 part Mefenoxam 2E in the tank-mix. 
 Thoroughly clean the chemical tank and inje ctor system. Flush system with clean water. 
 Maintain good agitation during the entire application period. 
 Uniform coverage is required for good control. 
 
5.0 REPLANT AND ROTATIONAL CROP RESTRICTIONS 
5.1 Replanting 
If replanting is necessary, additional applications of Mefenoxam 2E may be made, provided 
that the total amount of active ingredient in Mefenoxam 2E applied does not exceed the 
maximum allowed for the specific crop.

12 
 
5.2 Rotational Crop Restrictions 
 The following crops may be planted at the specified interval following application of 
Mefenoxam 2E. 
 
 
Crop, Crop Group, or Crop Subgroup 
Replant/Plant-Back 
Interval 
Alfalfa 
Apple 
Artichoke, globe 
Birdsfoot trefoil 
Brassica Head and Stem Vegetables, Crop Group 5-16 
Brassica Leafy Greens, Crop Subgroup 4-16B 
Bulb Vegetables, Crop Group 3-07 
Clover 
Corn 
Cotton, Crop Subgroup 20C 
Cucurbit Vegetables, Crop Group 9 
Fruiting Vegetables, Crop Group 8-10 
 
Grass Forage, Fodder, and Hay, Crop Group 17 
Herbs (fresh and dried), Crop Subgroup 19A 
Hops 
Leafy Greens, Crop Subgroup 4-16A 
Legume Vegetables, Crop Group 6-22 
Peanut 
Pineapple 
Root and Tuber Vegetables, Crop Group 1 
Soybean 
Stalk, Stem, and Leaf Petiole Vegetables, Crop Subgroups 22A and 22B 
Strawberry 
Succulent Shelled Beans, Crop Subgroup 6-22C 
Succulent Shelled Peas, Crop Subgroup 6-22D 
Sunflower 
Tobacco 
Wasabi 
 
 
0 days 
Cereal grains (except corn) 14 days 
Sugarcane 30 days 
Crops not intended for food or feed 0 days 
All other crops intended for food and feed 365 days 
 
6.0 RESTRICTIONS AND PRECAUTIONS 
See Section 7.0 for crop-specific Restrictions and Precautions. 
6.1 Use Restrictions 
 DO NOT use in greenhouses or other structures including lath houses, float houses, and 
hydroponic facilities, unless specified on this label. 
 DO NOT use for disease control in bedding plants, transplant trays, or nurseries except 
where specifically allowed in certain crop sections. 
 DO NOT use as a foliar application unless specified on this label.

13 
 DO NOT dip plants or roots, spray bare roots, or use a transplant water treatment with 
solutions containing Mefenoxam 2E except where specifically allowed in certain crop 
sections. 
 Maximum usage when applying both mefenox am- and metalaxyl-containing products to 
the same crop within the same season: DO NOT apply more than the maximum yearly 
total application rate for the active ingredient as stated on the label of the product 
containing the lowest yearly total on that crop. 
 Maximum application rates included for all uses in Section 7.0. 
 
6.2 Use Precautions 
 Avoid spray overlap as crop injury may occur. 
 
6.3 Spray Drift Management 
 AVOIDING SPRAY DRIFT AT THE APPLICAT ION SITE IS THE RESPONSIBILITY OF 
THE APPLICATOR AND THE GROWER. 
 To avoid spray drift, DO NOT apply when conditions favor drift beyond the target area. 
 The interaction of many equipment and weathe r-related factors determine the potential for 
spray drift. 
 
6.4 Spray Drift Advisory 
THE APPLICATOR IS RESPONSIBLE FOR AVOIDING OFF-SITE SPRAY DRIFT. BE 
AWARE OF NEARBY NON-TARGET SITES AND ENVIRONMENTAL CONDITIONS. 
6.4.1 IMPORTANCE OF DROPLET SIZE 
 An effective way to reduce spray drift is to apply large droplets. Use the largest droplets 
that provide target pest control. 
 While applying larger droplets will reduce spray dr ift, the potential for drift will be greater if 
applications are made improperly or under unfavorable environmental conditions. 
 
6.4.2 CONTROLLING DROPLET SIZE – GROUND BOOM 
 Volume-Increasing the spray volume so that larger droplets are produced will reduce 
spray drift. Use the highest practical spray volume for the application. If a greater spray 
volume is needed, consider using a nozzle with a higher flow rate. 
 Pressure-Use the lowest spray pressure specified for the nozzle to produce the target 
spray volume and droplet size. 
 Spray Nozzle-Use a spray nozzle that is designed for the intended application. Consider 
using nozzles designed to reduce drift. 
 
6.4.3 CONTROLLING DROPLET SIZE – AIRCRAFT 
 Adjust Nozzles-Follow nozzle manufacturer’s specifications for setting up nozzles. To 
reduce fine droplets, nozzles must be oriented parallel with the airflow in flight.

14 
 
6.4.4 BOOM HEIGHT – GROUND BOOM 
 Use the lowest boom height that is compat ible with the spray nozzles that will provide 
uniform coverage. For ground equipment, the boom must remain level with the crop and 
have minimal bounce. 
 
6.4.5 RELEASE HEIGHT - AIRCRAFT 
 Higher release heights increase the potential for spray drift. When applying aerially to 
crops, DO NOT spray at a height greater than 10 ft above the crop canopy, unless a 
greater application height is necessary for pilot safety. 
 
6.4.6 SHIELDED SPRAYERS 
 Shielding the boom or individual nozzles can reduce spray drift. Consider using shielded 
sprayers. 
 Verify that the shields are not interfering with the uniform deposition of the spray on the 
target area. 
 
6.4.7 TEMPERATURE AND HUMIDITY 
 When making applications in hot and dry conditi ons, use larger droplets to reduce effects 
of evaporation. 
 
6.4.8 TEMPERATURE INVERSIONS 
 Drift potential is high during a temperature inversion. 
 Temperature inversions are characterized by increasing temperature with altitude and are 
common on nights with limited cloud cover and light to no wind. 
 The presence of an inversion can be indica ted by ground fog or by the movement of 
smoke from a ground source or an aircraft smoke generator. 
 Smoke that layers and moves laterally in a concentrated cloud (under low wind 
conditions) indicates an inversion, while smoke that moves upward and rapidly dissipates 
indicates good vertical air mixing. 
 Avoid applications duri ng temperature inversions. 
 
6.4.9 WIND 
 Drift potential increases with wind speed. 
 AVOID APPLICATIONS DURING GUSTY WIND CONDITIONS. 
 Applicators need to be familiar with local wind patterns and terrain that could affect spray 
drift.

15 
 
7.0 CROP USE DIRECTIONS 
7.1 Alfalfa 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Alfalfa 
Birdsfoot trefoil 
Target Disease 
Rate 
pt/A 
(lb ai) Application Timing Use Directions 
Damping off 
(Pythium spp.) 
Root rot 
(Phytophthora 
 spp.) 
0.50 – 1.0 
(0.125-
0.25) 
At planting Soil Spray (broadcast): Apply as a 
broadcast soil surface spray. 
 
If alfalfa seed was previously treated with 
mefenoxam or metalaxyl as a seed dressing, 
or if an application was made while inter-
seeding into existing stands for renovation, 
use the 0.50 pt/A (0.125 lb ai) rate. 
 
 
 
 
0.50 
(0.125) 
 
 
Established 
plantings 
 
 
Soil Spray (broadcast): Apply as a 
broadcast soil surface spray when inter-
seeding into existing stands for renovation. 
 
Resistance Management: 
 Refer to Section 3.2. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 1.0 pt/A (equivalent to 0.25 lb ai/A mefenoxam) 
3) Minimum Application Interval: NA 
4) Maximum Annual Application Rate: 1.0 pt/A/year (equivalent to 0.25 lb ai/A/year mefenoxam) 
a) DO NOT exceed 0.25 lb ai/A/year of mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 1 application at the maximum application rate per year. 
6) DO NOT feed green forage or cut hay for 60 days following application. 
7) Pre-harvest Interval (PHI): 60 days

16 
 
7.2 Apple 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Apple, bearing trees Apple, non-bearing trees 
Target Disease 
Rate 
(lb ai) Application Timing Use Directions 
Collar rot 
Crown rot 
Root rot 
 (Phytophthora 
spp.) 
8.0 pt/A 
(2.0) 
or 
3.0 fl oz/1000 
sq ft 
Apply in the early spring 
before growth begins 
(established plantings) 
and in the fall after 
harvest but before the 
ground freezes. 
Soil Spray (broadcast, band, or via 
drip/micro-sprinkler irrigation): Apply 
to soil beneath the tree canopy or apply 
through irrigation water. 
 
The treated area is based on the area 
under the tree canopy or the area of the 
sprayed row. 
 
Use sufficient water volume to obtain 
thorough coverage of the soil. 
 
To calculate the rate as a band 
application, see Section 4.1.1. 
 
Diluted 
mixture: 1.0 
pt in 100 gal 
water 
(0.25) 
Apply in early spring 
before growth starts and 
in the fall after harvest, 
but before the ground 
freezes. 
On new plantings, delay 
the first application until 2 
weeks after planting. 
NOTE: Apply before 
symptoms appear. 
Soil Drench: Apply the diluted mixture 
around the trunk of each tree. 
Use the amount of diluted mixture based 
upon the following tree parameters: 
 
Trunk diameter at 
12 inches above 
the soil line 
Quantity of 
diluted mixture 
(lb ai) 
<1 inch 1 qt (0.00063) 
1-3 inches 3 qt (0.0019) 
4 inches 3.5 qt (0.0022) 
5 inches 4 qt (0.0025) 
 
Use Mefenoxam 2E in conjunction with 
good cultural practices and rootstocks 
that are most tolerant to disease. 
Resistance Management: 
 Refer to Section 3.2. 
Precaution: 
 Mefenoxam 2E will not revitalize trees showing moderate to severe disease symptoms. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 8.0 pt/A (equivalent to 2.0 lb ai/A mefenoxam) 
3) Minimum Application Interval: 90 days 
4) Maximum Annual Application Rate: 16.0 pt/A/year (equivalent to 4.0 lb ai/A/year mefenoxam)

17 
a) DO NOT exceed 4.0 lb ai/A/year of mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 2 applications at the maximum application rate per year. 
6) DO NOT graze or feed cover crops in treated orchards. 
7) Pre-harvest Interval (PHI): NA 
 
7.3 Artichoke 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Artichoke, globe 
Target Disease 
Rate 
pt/A 
(lb ai) Application Timing Use Directions 
Damping off 
 (Pythium spp.) 
Root rot 
(Phytophthora 
spp.) 
2.0 – 4.0 
(0.50-1.0) 
At planting Soil Spray (broadcast): Apply as a 
broadcast soil surface spray. 
 
Resistance Management: 
 Refer to Section 3.2. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 4.0 pt/A (equivalent to 1.0 lb ai/A mefenoxam) 
3) Minimum Application Interval: NA 
4) Maximum Annual Application Rate: 4.0 pt/A/year (equivalent to 1.0 lb ai/A/year mefenoxam) 
a) DO NOT exceed 1.0 lb ai/A/year of mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 1 application at the maximum application rate per year. 
6) Pre-harvest Interval (PHI): 200 days

18 
 
7.4 Avocado 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Avocado 
Target Disease 
Rate 
(lb ai) Application Timing Use Directions 
Root rot 
(Phytophthora 
spp.) 
Diluted mixture: 
0.50 fl oz in 18 
gal water 
 
At transplanting Sleeve Drench: Drench the roots inside 
the sleeve with 1 qt of the diluted mixture 
per tree. 
 
Sleeve drench does not replace other 
soil applications for long-term control of 
root rot. 
 
2.0 – 8.0 pt/A 
(0.5-2.0) 
 
or 
 
1.0 – 2.0 fl 
oz/1000 gal 
water 
(3.9-7.8 ppm) 
Start of the growing season 
at transplanting or when soil 
tests detect the presence of 
Phytophthora. 
 
Two additional applications 
may be made at 3-month 
intervals. 
 
 
Irrigation: Apply via the irrigation 
system (drip, micro-emitter, or 
sprinkler). 
 
 
Use 2.0 pt/A if the trees have a canopy 
diameter of 2 ft. Increase the rate as the 
canopy diameter increases. For canopy 
diameters of 15 ft or more, use the 
8.0 pt/A rate. 
 
 
Soil Spray: Apply to the soil directly 
under/over the drip emitter. Use 
irrigation to incorporate the material into 
the soil. If there is more than one 
emitter, distribute the amount of 
Mefenoxam 2E among the emitters. 
 
 
For new plantings, use Phytophthora-
resistant rootstocks. 
 
Resistance Management: 
 Refer to Section 3.2. 
Precaution: 
 Mature trees in moderate to advanced sta ge of decline cannot be cured with Mefenoxam 2E. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 8.0 pt/A (equivalent to 2.0 lb ai/A mefenoxam) 
3) Minimum Application Interval: 90 days 
4) Maximum Annual Application Rate: 24.0 pt/A/year (equivalent to 6.0 lb ai/A/year mefenoxam) 
a) DO NOT exceed 6.0 lb ai/A/year of soil-applied mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 3 applications at the maximum application rate per year. 
6) Pre-harvest Interval (PHI): 28 days

19 
7.5 Berry and Small Fruit 
7.5.1 BUSHBERRY, CROP SUBGROUP 13-07B 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Aronia berry 
Blueberry, highbush 
Blueberry, lowbush 
Buffalo currant 
Chilean guava 
Currant, black 
Currant, red 
Elderberry 
European barberry 
Gooseberry 
Highbush cranberry 
Honeysuckle, edible 
Huckleberry 
 
Jostaberry 
Juneberry (Saskatoon Berry) 
Lingonberry 
Native currant 
Salal 
Sea buckthorn 
 
Target Disease 
Rate 
pt/A 
(lb ai) Application Timing Use Directions 
Root rot 
 (Phytophthora spp.) 
7.2 
(1.8) 
 
 
 
New Plantings: 
Apply at time of planting. 
 
 
Soil Application (broadcast, band, 
or via drip/micro-sprinkler 
irrigation): 
Make one application at planting and 
reapply once during a period 
favorable for root rot. 
 
For band applications, use an 18-inch 
band. To calculate the rate as a band 
application, see Section 4.1.1. 
 
 
 
 
 
Established Plantings: 
Apply before the plants 
start to grow in the spring. 
 
One additional application 
may be made to coincide 
with the period most 
favorable for root rot 
development. 
 
Make a soil-directed application 
towards the base of the plant in a 3-ft 
band over the row or via the drip 
irrigation. 
 
To calculate the rate as a band 
application, see Section 4.1.1. 
 
 
 
Use Mefenoxam 2E in conjunction 
with good cultural practices to 
minimize disease. 
Resistance Management: 
 Refer to Section 3.2. 
Precaution: 
 Mefenoxam 2E will not revitalize plants showin g moderate to severe root rot symptoms. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 7.2 pt/A (equivalent to 1.8 lb ai/A mefenoxam) 
3) Minimum Application Interval: 90 days 
4) Maximum Annual Application Rate: 14.4 pt/A/year (equivalent to 3.6 lb ai/A/year mefenoxam) 
a) DO NOT exceed 3.6 lb ai/A/year of soil-applied mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 2 applications at the maximum application rate per year. 
6) Pre-harvest Interval (PHI): 0 days

20 
 
7.5.2 CANEBERRY, CROP SUBGROUP 13-07A 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Blackberry 
Loganberry 
Raspberry, black 
Raspberry, red 
Raspberry, wild 
Target Disease 
Rate 
pt/A 
(lb ai) Application Timing Use Directions 
Root rot 
(Phytophthora 
spp.) 
7.2 
(1.8) 
New Plantings: Apply at time 
of planting. 
Soil Application (broadcast, band, 
or via drip/micro-sprinkler 
irrigation): 
Make one application at planting and 
reapply once during a period 
favorable for root rot. 
 
For band applications, use an 18-
inch band. To calculate the rate as a 
band application, see Section 4.1.1. 
 
 Established plantings: Apply 
before the plants start to grow 
in the spring. 
 
One additional application may 
be made to coincide with the 
period most favorable for root 
rot development. 
Make a soil-directed application 
towards the base of the plant in a 3-
ft band over the row or via the drip 
irrigation. 
 
To calculate the rate as a band 
application, see Section 4.1.1. 
 
 
 
Use Mefenoxam 2E in conjunction 
with good cultural practices to 
minimize disease. 
Resistance Management: 
 Refer to Section 3.2. 
Precaution: 
 Mefenoxam 2E will not revitalize plants showin g moderate to severe root rot symptoms. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 7.2 pt/A (equivalent to 1.8 lb ai/A mefenoxam) 
3) Minimum Application Interval: 90 days 
4) Maximum Annual Application Rate: 14.4 pt/A/year (equivalent to 3.6 lb ai/A/year mefenoxam) 
a) DO NOT exceed 3.6 lb ai/A/year of soil-applied and 0.2 lb ai/A/year of foliar-applied mefenoxam- and 
metalaxyl-containing products. 
5) DO NOT use an adjuvant. 
6) DO NOT make more than 2 applications at the maximum application rate per year. 
7) Pre-harvest Interval (PHI): 45 days

21 
 
7.5.3 CRANBERRY 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Cranberry 
Target Disease 
Rate 
pt/A 
(lb ai) Application Timing Use Directions 
Root rot 
(Phytophthora spp.) 
2.0 – 3.5 
(0.5-0.875) 
 
Make 3 applications: 
Make the first 
application in the fall 
after harvest, the 
second application in 
the spring, and the final 
application up to, but 
no later than, 45 days 
before harvest. 
Soil Spray (broadcast): 
Apply as a soil spray by ground or via 
chemigation (Section 4.5) equipment. 
 
 
Resistance Management: 
 Refer to Section 3.2. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 3.5 pt/A (equivalent to 0.875 lb ai/A mefenoxam) 
3) Minimum Application Interval: 90 days 
4) Maximum Annual Application Rate: 10.5 pt/A/year (equivalent to 2.625 lb ai/A/year mefenoxam) 
a) DO NOT exceed 2.625 lb ai/A/year of soil-applied mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 3 applications at the maximum application rate per year. 
6) DO NOT apply by air. 
7) Pre-harvest Interval (PHI): 45 days

22 
 
7.5.4 SMALL FRUIT VINE CLIMBING (EXCEPT GRAPE), CROP SUBGROUP 13-07E 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Amur river grape 
Gooseberry 
Kiwifruit, fuzzy 
Kiwifruit, hardy 
Maypop 
Schisandra berry 
Target Disease 
Rate 
(lb ai) Application Timing Use Directions 
Root and Crown rot 
(Pythium and 
Phytophthora spp.) 
11.2 – 22.4 fl 
oz/40 gal 
water 
(0.175-0.35) 
 
Make the first application 
in the fall after harvest or 
in February or early 
March. 
 
Make a second 
application in the spring 
or approximately 60 days 
after the February or 
March application. 
 
Soil Drench: Apply 1.0 qt of 
Mefenoxam 2E solution as a soil 
drench in a one square foot area 
around the base of each vine. 
 
At the labeled rate of 11.2-22.4 fl 
oz/40 gallons of water, this will apply 
0.175-0.350 lb ai/A if the planting 
density is 160 vines per acre. 
 
22.4 fl oz/A 
(0.35) 
 
Make the first application 
in April and follow with 
two additional 
applications on 30-day 
intervals. Make the 
fourth application in 
September and the final 
application approximately 
30 days later, which must 
be at least 7 days before 
harvest. 
Banded Soil Application: Make up 
to five applications as a spray toward 
the soil in a 2- to 3-ft band on each 
side of the row. 
 
To calculate the rate as a band 
application, see Section 4.1.1. 
Resistance Management: 
 Refer to Section 3.2. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 22.4 fl oz/A (equivalent to 0.35 lb ai/A mefenoxam) 
3) Minimum Application Interval: 30 days 
4) Maximum Annual Application Rate: 7.0 pt/A/year (equivalent to 1.75 lb ai/A/year mefenoxam) 
a) DO NOT exceed 1.75 lb ai/A/year of soil-applied mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 5 applications at the maximum application rate per year. 
6) Pre-harvest Interval (PHI): 7 days

23 
 
7.5.5 STRAWBERRY 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Strawberry 
Strawberry, field nursery 
Target Disease 
Rate 
pt/A 
(lb ai) Application Timing Use Directions 
Leather rot 
(Phytophthora 
cactorum) 
Red stele 
(Phytophthora 
fragariae) 
Vascular collapse 
(Phytophthora 
cactorum) 
2.0 
(0.5) 
Annual plantings: Apply up to 
3 times per crop. Make the first 
application after transplanting. 
Make the second application 30 
days before the beginning of 
harvest or at fruit set. Make the 
third application during harvest, 
depending on disease pressure 
and environmental conditions. 
 
 
For ANNUAL AND ESTABLISHED 
PLANTINGS only 
 
Soil Application: Ground (banded), 
drip, or overhead chemigation 
(Section 4.5). 
 
 
When applying through drip 
irrigation, calculate the rate as a 
band application (Section 4.1.1) with 
a band width equal to the root zone 
width. Inject Mefenoxam 2E into the 
irrigation water. 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Mefenoxam 2E may be applied the 
day of harvest. 
 
Established plantings: Apply 
up to 3 times per crop. Make 
the first application in the spring 
after the ground thaws and 
before first bloom. Make the 
second application after harvest 
in the fall. For control of 
leather rot, make an additional 
application during the growing 
season at fruit set. 
 Apply to young plants in field 
nurseries. 
For FIELD NURSERY application 
only 
 
Soil Application: Ground (banded), 
drip, or overhead chemigation 
(Section 4.5). 
 
When applying through drip 
irrigation, calculate the rate as a 
band application (Section 4.1.1) with 
a band width equal to the root zone 
width. Inject Mefenoxam 2E into the 
irrigation water. 
Resistance Management: 
 Refer to Section 3.2.

24 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 2.0 pt/A (equivalent to 0.5 lb ai/A mefenoxam) 
3) Minimum Application Interval: 30 days 
4) Maximum Annual Application Rate: 6.0 pt/A/year (equivalent to 1.5 lb ai/A/year mefenoxam) except 
for field nursery: 4.0 pt/A/year (equivalent to 1.0 lb ai/A/year mefenoxam) 
a) DO NOT exceed 1.5 lb ai/A/year of soil-applied mefenoxam- and metalaxyl-containing products. 
b) For field nursery use only, DO NOT exceed 1.0 lb ai/A/per plant production cycle of mefenoxam- 
and metalaxyl-containing products. 
5) DO NOT make more than 3 applications per crop except when used in a field nursery setting, then only 
make 2 applications per plant production cycle. 
6) DO NOT use in strawberry field nurseries east of the Rocky Mountains. 
7) Pre-harvest Interval (PHI): 0 days 
 
 
7.6 Brassica Head and Stem Vegetables, Crop Group 5-16 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Broccoli 
Brussels sprouts 
Cabbage 
Cabbage, Chinese, napa 
Cauliflower 
 
 
Target Disease 
Rate 
pt/A 
(lb ai) 
Application Timing Use Directions 
Basal stem rot 
 (Phytophthora 
spp.) 
2.0 – 4.0 
(0.5-1.0) 
Preplant incorporated 
 
 
 
 
 
 
 
At planting 
Preplant Incorporated (broadcast or 
band): 
 Apply in water or liquid fertilizer and 
incorporate in the top 2 inches of soil. 
 
 
 
 
Soil Spray (broadcast or band): 
 Apply in water or liquid fertilizer at 
planting. 
 
 
For banded applications, use a 7-inch 
band. To calculate the rate as a band 
application, see Section 4.1.1. 
 
 
Injection (drip irrigation): Inject 
Mefenoxam 2E into the irrigation water 
at the labeled rates. 
 
 
Damping off 
 ( Pythium spp.) 
0.5 – 1.0 
(0.125-0.25) 
 
Preplant incorporated Preplant Incorporated (broadcast or 
band): 
Apply in water or liquid fertilizer and 
incorporate in the top 2 inches of soil. 
 
For banded applications, use a 7-inch 
band. To calculate the rate as a band 
application, see Section 4.1.1.

25 
Downy mildew 
 ( Peronospora 
parasitica) 
0.25 – 0.5 
(0.063-
0.125) 
 
Apply when conditions are 
favorable for disease but 
before infection on a 14-
day schedule. 
Foliar Application: Apply as a foliar 
spray by ground or air. 
 
Mefenoxam 2E must be used in a 
tank-mix with other fungicides 
registered for control of downy mildew. 
Apply with the full label rate of the 
tank-mix partner fungicide. 
 
 
Resistance Management: 
 Refer to Section 3.2. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 
a) Soil: 4.0 pt/A (equivalent to 1.0 lb ai/A mefenoxam) 
b) Foliar: 0.5 pt/A (equivalent to 0.125 lb ai/A mefenoxam) 
3) Minimum Application Interval: 
a) Soil: NA 
b) Foliar: 14 days 
4) Maximum Annual Application Rate: Soil: 4.0 pt/A/year (equivalent to 1.0 lb ai/A/year mefenoxam) 
Foliar: 2.0 pt/A/year (equivalent to 0.50 lb ai/A/year mefenoxam) 
a) DO NOT exceed 1.0 lb ai/A/year of soil-applied and 0.50 lb ai/A/year of foliar-applied mefenoxam- 
and metalaxyl-containing products. 
5) DO NOT apply foliar sprays of Mefenoxam 2E without a labeled tank-mix partner. 
6) DO NOT apply Mefenoxam 2E mixture in fields where downy mildew is already established. 
7) DO NOT make more than 1 soil-applied application and 4 foliar-applied applications at the maximum 
application rate per year. 
8) Pre-harvest Interval (PHI): 7 days 
7.7 Brassica Leafy Greens, Crop Subgroup 4-16B 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Arugula 
Broccoli, Chinese 
Broccoli raab 
Cabbage, Abyssinian 
Cabbage, Chinese, bok choy 
Cabbage, seakale 
Collards 
Cress, garden 
Cress, upland 
Hanover salad 
Kale 
Maca, leaves 
Mizuna 
Mustard greens 
Radish, leaves 
Rape greens 
Rocket, wild 
Shepherd’s purse 
Turnip greens (greens only) 
Watercress* 
 
Target Diseases Rate 
(lb ai) Application Timing Use Directions 
Basal stem rot 
 (Phytophthora 
spp.) 
 
 
 
2.0 – 4.0 pt/A 
(0.50-1.0) 
Preplant incorporated 
 
 
 
 
 
 
At planting 
Preplant Incorporated (broadcast 
or band): 
Apply in water or liquid fertilizer and 
incorporate in the top 2 inches of 
soil. 
 
 
Soil Spray (broadcast or band): 
Apply in water or liquid fertilizer at 
planting. 
 
For banded applications, use a 7-
inch band. To calculate the rate as a 
band application, see Section 4.1.1.

26 
 
Injection (drip irrigation): Inject 
Mefenoxam 2E into the irrigation 
water at the labeled rates. 
 
 
Damping off 
 ( Pythium spp.) 
0.50 – 1.0 pt/A 
(0.125-0.25) 
Preplant incorporated Preplant Incorporated (broadcast 
or band): 
Apply in water or liquid fertilizer and 
incorporate in the top 2 inches of 
soil. 
 
For banded applications, use a 7-
inch band. To calculate the rate as a 
band application, see Section 4.1.1. 
 
Downy mildew 
 ( Peronospora 
parasitica) 
0.25 – 0.50 
pt/A 
(0.063-0.125) 
 
Apply when conditions are 
favorable for disease but 
before infection on a 14-day 
schedule. 
Foliar Application: Apply as a foliar 
spray by ground or air. 
 
Mefenoxam 2E must be used in a 
tank-mix with other fungicides 
registered for control of downy 
mildew. Apply with the full label rate 
of the tank-mix partner fungicide. 
 
 
NOTE: Foliar applications to turnip 
plants may not be made to dual 
purpose turnip cultivars or varieties 
which produce a harvestable root. 
 
Arugula and Cress 
ONLY 
Damping off 
 (Pythium spp.) 
2.0 – 4.0 pt/A 
(0.50-1.0) 
Preplant incorporated 
 
 
 
 
 
 
At planting 
Preplant Incorporated (broadcast 
or band): 
Apply in water or liquid fertilizer and 
incorporate in the top 2 inches of 
soil. 
 
 
Soil Spray (broadcast or band): 
Apply in water or liquid fertilizer at 
planting. 
 
 
 
For banded applications, use a 7-
inch band. To calculate the rate as a 
band application, see Section 4.1.1. 
 
 
Injection (drip irrigation): Inject 
Mefenoxam 2E into the irrigation 
water at the labeled rates.

27 
 Transplant 
water: 
 
0.50-1.0 pt 
/100–200 gal 
water/A 
 
(0.125-0.25) 
At transplant or immediately 
following planting. 
 
Apply in transplant water or 
immediately following planting via 
soil drench. 
 
Apply in at least 100 gallons of 
transplant water per acre. 
 
*Not for use in California. 
Resistance Management: 
 Refer to Section 3.2. 
Precautions: 
 There is a risk of plant injury with transplant water application: 
o Crop injury is more likely when applied in le ss than 100 gallons/acre. Injury is temporary and 
typically disappears within three weeks. 
o Pre-mixing Mefenoxam 2E in a t ank separate from the transplant water source tank will help to 
prevent incompatibility with fertilizers or other pesticides in the transplant water solution. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 
a) Soil: 4.0 pt/A (equivalent to 1.0 lb ai/A mefenoxam) 
b) Foliar: 0.50 pt/A (equivalent to 0.125 lb ai/A mefenoxam) 
3) Minimum Application Interval: 
a) Soil: NA 
b) Foliar: 14 days 
4) Maximum Annual Application Rate: Soil: 4.0 pt/A/year (equivalent to 1.0 lb ai/A/year mefenoxam) 
Foliar: 2.0 pt/A/year (equivalent to 0.5 lb ai/A/year mefenoxam) 
a) DO NOT exceed 1.0 lb ai/A/year of soil-applied and 0.50 lb ai/A/year of foliar-applied mefenoxam- 
and metalaxyl-containing products. 
5) DO NOT make more than 1 soil-applied application and 4 foliar-applied applications at the maximum 
application rate per year. 
6) DO NOT apply foliar sprays of Mefenoxam 2E without a labeled tank-mix partner for downy mildew. 
7) DO NOT apply Mefenoxam 2E mixture in fields where downy mildew is already established. 
8) DO NOT apply to dual purpose turnip cultivars or varieties which produce a harvestable root. 
9) Pre-harvest Interval (PHI): 7 days

28 
 
7.8 Bulb Vegetables, Crop Group 3-07 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Onion, Bulb Onion, Green 
Daylily,bulb 
Fritillaria, bulb 
Garlic, bulb 
Garlic, great-headed, 
bulb 
Garlic, serpent, bulb 
 
Lily, bulb 
Onion, bulb 
Onion, Chinese, bulb 
Onion, pearl 
Onion, potato, bulb 
Shallot, bulb 
Chive, fresh leaves 
Chive, Chinese, fresh 
leaves 
Elegans hosta 
Fritillaria, leaves 
Kurrat 
Lady’s leek 
Leek 
Leek, wild 
 
Onion, Beltsville 
bunching 
Onion, fresh 
Onion, green 
Onion, macrostem 
Onion, tree, tops 
Onion, Welsh, tops 
Shallots, fresh leaves 
Target Disease 
Rate 
pt/A 
(lb ai) Application Timing Use Directions 
Damping off 
(Pythium spp.) 
1.0-2.0 
(0.25-0.5) 
Preplant incorporated 
 
 
 
 
 
At planting 
Preplant Incorporated (broadcast or 
band): 
Apply in water or liquid fertilizer and 
mechanically incorporate in the top 2 
inches of soil. 
 
Soil Spray (broadcast or band): 
Apply in water or liquid fertilizer at 
planting. 
 
For banded applications, use a 7-inch 
band. To calculate the rate as a band 
application, see Section 4.1.1. 
Resistance Management: 
 Refer to Section 3.2. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 2.0 pt/A (equivalent to 0.5 lb ai/A mefenoxam) 
3) Minimum Application Interval: NA 
4) Maximum Annual Application Rate: 4.0 pt/A/year (equivalent to 1.0 lb ai/A/year mefenoxam) 
a) For onions (bulb): DO NOT exceed 1.0 lb ai/A/year of soil-applied and 0.5 lb ai/A/year of foliar-
applied mefenoxam- and metalaxyl-containing products. 
b) For onions (green): DO NOT exceed 1.0 lb ai/A/year of soil-applied and 0.3 lb ai/A/year of foliar-
applied mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 2 applications at the maximum application rate per year. 
6) Pre-harvest Interval (PHI): NA

29 
7.9 Cacao 
 
7.10 Citrus Fruit, Crop Group 10 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Calamondin 
Citrus citron 
Citrus hybrids 
chironja 
tangelo 
 tangor 
Grapefruit 
Kumquat 
Lemon 
Lime 
Mandarin (tangerine) 
Orange, sour 
Orange, sweet 
Pummelo 
Satsuma mandarin 
 
Target Disease 
Rate 
(lb ai) Application Timing Use Directions 
Brown rot 
Citrus foot rot 
Gummosis 
Root rot 
Trunk canker 
(Phytophthora spp.) 
 
NOTE: for best 
Phytophthora 
control, use a 
combination of 
cultural practices, 
fungicides with 
Broadcast 
4.0 pt/A 
(1.0) 
 
Irrigation 
1.0 pt/grove 
acre 
(0.25) 
 
 
California only: 
Broadcast 
4.0 – 8.0 pt/A 
Citrus Resets or New 
Plantings: Make the 
first application after 
planting. Make two or 
three applications per 
year (spring + summer, 
summer + fall, or spring 
+ summer + fall). 
Spray Boom: Apply to soil beneath 
the tree canopy. If rain is not 
expected within 24 hours after 
application, sprinkler irrigate with ½ 
to 1 inch of water to move product 
into root zone. 
 
Irrigation: Mefenoxam 2E can be 
applied through irrigation water 
(micro-sprinkler or drip). 
Crops (Including all cultivars, varieties, and/or hybrids of these) 
Cacao 
Target Disease 
Rate 
fl oz/A 
(lb ai) 
Application Timing Use Directions 
Black pod rot 
 (Phytophthora spp.) 
0.64 
(0.01) 
Make the first 
application prior to 
disease development, 
and additional 
applications on a 21-
day schedule. 
Foliar/Pod Spray: Apply in mixture 
with a copper fungicide. 
Apply in sufficient volume of water to 
ensure complete coverage of the 
canopy and developing pods. 
Precaution: 
 Make no more than two consecutive applications of Mefenoxam 2E or other Group 4 fungicides before 
alternating with a fungicide that is not in Group 4. 
Resistance Management: 
 Refer to Section 3.2. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 0.64 fl oz/A (equivalent to 0.01 lb ai/A mefenoxam) 
3) Minimum Application Interval: 21 days 
4) Maximum Annual Application Rate: 2.56 fl oz/A/year (equivalent to 0.04 lb ai/A/year mefenoxam) 
a) DO NOT exceed 0.04 lb ai/A/year of mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 4 applications at the maximum application rate per year. 
6) Pre-Harvest Interval (PHI): 30 days

30 
different modes of 
action, and resistant 
varieties. 
(1.0-2.0) 
 
Irrigation 
1.0 – 2.0 
pt/grove acre 
(0.25-0.50) 
 
Water Ring 
Drench 
2.0 – 3.0 fl 
oz/100 gal water 
(0.03-0.05) 
 
Water Ring Drench: Apply 5 
gallons of the mix around the base 
of each tree within the watering ring 
of resets or new plantings. 
Newly planted to 
6 months: 
1.0 fl oz/20 trees 
(0.016) 
 
 
 
 
 
Trees 
>6months: 
2.0-3.0 fl oz/20 
trees 
(0.03-0.05) 
Individual Tree 
Treatment for 
Resets/New Plantings: 
Newly planted to 6 
months 
 
 
 
 
Trees >6 months 
Mix desired amount of Mefenoxam 
2E in a water solution. Apply as a 
directed spray to individual trees (8-
12 fl oz solution/tree) around the 
base of the tree and outwards to 
cover the fibrous root system. 
 
Follow with sprinkler irrigation to 
move product into the root zone. 
 
 
 
May be tank mixed with other 
approved pesticides. 
Broadcast 
2.0 – 4.0 pt/A 
(0.5-1.0) 
 
Irrigation 
1.0 – 2.0 
pt/grove acre 
(0.25-0.50) 
 
 
California only: 
Broadcast 
2.0 – 12.0 pt/A 
(0.5-3.0) 
 
Established Plantings: 
Begin applications 
during the spring root 
flush period. 
 
One or two additional 
applications may be 
made to coincide with 
flushes of root growth. 
 
Time the applications as 
in the Citrus Resets or 
New Plantings section 
above. 
 
Spray Boom: Apply to soil beneath 
the tree canopy. If rain is not 
expected within 24 hours after 
application, sprinkler irrigate with ½ 
to 1 inch of water to move product 
into root zone. 
 
Irrigation: Mefenoxam 2E can be 
applied through irrigation water 
(micro-sprinkler or drip). 
 
 
 
Consult local extension bulletins for 
additional use directions. 
4 pt in 3 gal 
water 
(1.0) 
 
Florida only: 
4 pt in 10 gal 
water 
(1.0) 
Trunk Spray for 
Gummosis: 
Apply up to 3 times per 
year. 
Spray the trunks to thoroughly wet 
the cankers. 
 
 
 
 
 
 
 
 
 
 
Resistance Management: 
 Refer to Section 3.2. 
USE RESTRICTIONS

31 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 12.0 pt/A (equivalent to 3.0 lb ai/A mefenoxam) 
3) Minimum Application Interval: 90 days 
4) Maximum Annual Application Rate: 24.0 pt/A/year (equivalent to 6.0 lb ai/A/year mefenoxam) 
a) DO NOT exceed 6.0 lb ai/A/year of mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 3 applications at the maximum application rate per year. 
6) DO NOT apply to bare roots. 
7) DO NOT apply to citrus in field or greenhouse nurseries. 
8) DO NOT make trunk gummosis sprays and soil applications to the same tree in the same cropping 
season. 
9) DO NOT apply rates higher than 4.0 pt/A (1.0 lb ai) to citrus resets or new plantings (less than 5 years 
old) in FL, PR, or TX to prevent potential phytotoxicity. 
10) DO NOT use on the highly Phytophthora susceptible sweet orange rootstock in FL. 
11) DO NOT apply tank mixes of Mefenoxam 2E and pre-emergent herbicides to trees less than 3 years 
old. Apply the herbicide first; then wait 3-4 weeks to apply Mefenoxam 2E. 
12) Pre-harvest Interval (PHI): 0 days 
 
 
7.11 Clover 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Clover 
Target Disease 
Rate 
pt/A 
(lb ai) Application Timing Use Directions 
Damping off 
(Pythium spp.) 
Root rot 
(Phytophthora 
spp.) 
 
0.5-1.0 
(0.125-0.25) 
At planting Soil Spray (broadcast): Apply as a 
broadcast soil surface spray. 
 
If the clover seed was previously 
treated with mefenoxam or metalaxyl 
as a seed dressing, use the 0.5 pt/A 
(0.125 lb ai) rate. 
Resistance Management: 
 Refer to Section 3.2. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 1.0 pt/A (equivalent to 0.25 lb ai/A mefenoxam) 
3) Minimum Application Interval: NA 
4) Maximum Annual Application Rate: 1.0 pt/A/year (equivalent to 0.25 lb ai/A/year mefenoxam) 
a) DO NOT exceed 0.25 lb ai/A/year of soil-applied mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 1 application at the maximum application rate per year. 
6) DO NOT feed or cut hay for 90 days following application. 
7) Pre-harvest Interval (PHI): 90 days

32 
 
7.12 Cotton, Crop Subgroup 20C 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Cotton 
Target Disease 
Rate 
(lb ai) Application Timing Use Directions 
Root rot 
(Phytophthora 
spp.) 
Seed rot 
(Pythium ultimum) 
Seedling blight 
(Pythium 
aphanidermatum) 
0.15-0.30 fl 
oz/1000 row ft 
(0.03-0.063) 
 
 
Equivalent to 2.2 
– 4.4 fl oz/A for 
38-inch 
rowspacing 
At planting Apply as an in-furrow spray in water 
or liquid fertilizer. Direct the spray into 
the furrow over the seed just before 
the seeds are covered. 
 
 
To calculate the rate as an in-furrow 
application, see Section 4.1.2. 
Resistance Management: 
 Refer to Section 3.2. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 0.30 fl oz/1000 row ft (equivalent to 0.063 lb ai/A mefenoxam) 
3) Minimum Application Interval: NA 
4) Maximum Annual Application Rate: 0.30 fl oz/1000 row ft/year (equivalent to 0.063 lb ai/A/year 
mefenoxam) 
a) DO NOT exceed 0.125 lb ai/A/year of soil-applied mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 1 application at the maximum application rate per year. 
6) Pre-harvest Interval (PHI): NA

33 
 
7.13 Cucurbit Vegetables, Crop Group 9 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Chayote (fruit) 
Chinese waxgourd (Chinese 
preserving melon) 
Citron melon 
Cucumber 
Gherkin 
Gourd, edible 
Hyotan 
Cucuzza 
Hechima 
Chinese okra 
Momordica spp. 
Balsam apple 
Balsam pear 
Bitter melon 
Chinese cucumber 
Muskmelon 
Cantaloupe 
Casaba 
Crenshaw melon 
Golden pershaw melon 
Honeydew melon 
Honey balls 
Mango melon 
Persian melon 
Pineapple melon 
Santa Claus melon 
Snake melon 
True cantaloupe 
Pumpkin 
Squash, summer 
Crookneck squash 
Scallop squash 
Straightneck squash 
Vegetable marrow 
Zucchini 
Squash, winter 
Acorn squash 
Butternut squash 
Calabaza 
Hubbard squash 
Spaghetti squash 
Watermelon 
Target Disease 
Rate 
 
(lb ai) Application Timing Use Directions 
Damping off/Root rot 
(Pythium spp.) 
 
Suppression: 
Phytophthora blight 
(Phytophthora 
capsici) 
 
2.0 – 4.0 
pt/A 
(0.5-1.0) 
 
 
Preplant incorporated 
 
 
 
 
 
At planting 
Preplant Incorporated (broadcast 
or band): Apply in water or liquid 
fertilizer and incorporate in the top 2 
inches of soil. 
 
 
Soil Spray (broadcast or band): 
Apply in water or liquid fertilizer at 
planting. 
 
 
For banded applications, use a 7-
inch band. To calculate the rate as a 
band application, see Section 4.1.1. 
 
 
Injection (drip irrigation): Inject 
Mefenoxam 2E into the irrigation 
water at the labeled rates. 
 
 
 0.50 – 0.8 
pt/A 
(0.125-0.20) 
 
 
 
Subsequent 
applications: If soil 
applications were made 
at planting, two additional 
applications may be 
made at 20- to 30-day 
intervals. 
Soil Spray (directed): Direct the 
spray to the base of the plants and 
cover 6-8 inches of the soil on either 
side of the plants. 
 
Incorporate mechanically or 
sprinkler-irrigate to move 
Mefenoxam 2E into the root zone.

34 
Injection (drip irrigation): Inject 
Mefenoxam 2E into the irrigation 
water at the labeled rates. 
Suppression: 
Phytophthora blight 
(Phytophthora 
capsici) 
 
Transplant 
water: 
 
 0.50-1.0 
pt/100 – 200 
gal water/A 
 
(0.125-0.25) 
At transplant 
 
In fields with a history of 
Phytophthora capsici 
blight, make a follow-up 
drip application of 
Mefenoxam 2E 14-21 
days after transplanting. 
Apply in transplant water or 
immediately following planting via 
soil drench. 
 
Apply in at least 100 gallons of 
transplant water per acre. 
Resistance Management: 
 Refer to Section 3.2. 
Precautions: 
 There is a risk of plant injury with transplant water application. 
o Crop injury is more likely when applied in less than 100 gallons/acre. Injury is temporary and 
typically disappears within three weeks. 
o Pre-mixing Mefenoxam 2E in a t ank separate from the transplant water source tank will help to 
prevent incompatibility with fertilizers or other pesticides in the transplant water solution. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 4.0 pt/A (equivalent to 1.0 lb ai/A mefenoxam) 
3) Minimum Application Interval: 20 days unless following transplant water application: 14 days 
4) Maximum Annual Application Rate: Soil: 4.0 pt/A/year (equivalent to 1.0 lb ai/A/year mefenoxam) 
Foliar: 1.6 pt/A/year (equivalent to 0.4 lb ai/A/year mefenoxam) 
a) DO NOT exceed 1.0 lb ai/A/year of soil-applied and 0.5 lb ai/A/year of foliar-applied mefenoxam- 
and metalaxyl-containing products. 
5) DO NOT make more than 1 soil-applied application and 2 soil-directed (foliar) applications at the 
maximum application rate per year OR 1 soil-applied application and 3 soil-directed (foliar) 
applications at the minimum application rate per year. 
6) Pre-harvest Interval (PHI): 5 days

35 
 
7.14 Fruiting Vegetables, Crop Group 8-10 
 
Crops (including all cultivars, varieties, and/or hybrids of these) 
African eggplant 
Bush tomato 
Bell pepper 
Cocona 
Currant tomato 
Eggplant 
Garden huckleberry 
 
Goji berry 
Groundcherry 
Martynia 
Naranjilla 
Okra 
Pea eggplant 
Pepino 
 
Nonbell pepper 
Roselle 
Scarlet eggplant 
Sunberry 
Tomatillo 
Tomato 
Tree tomato 
Target Disease 
Rate 
(lb ai) Application Timing Use Directions 
Damping off 
(Pythium spp.) 
 
Suppression: 
Crown rot 
(Phytophthora 
capsici) 
2.0 pt/A 
(0.5) 
Preplant or at planting 
 
For direct seeded peppers, 
apply preplant or prior to 
emergence. 
 
 
Soil Spray (broadcast or band): 
Apply in water or liquid fertilizer 
preplant or at planting. 
 
 
For banded applications, use a 
12- to 16-inch band. To calculate 
the rate as a band application, see 
Section 4.1.1. 
 
Injection (drip irrigation): Inject 
Mefenoxam 2E into the irrigation 
water. 
 
Post Planting: Make 2 post-
directed applications at 30-
day intervals following 
planting. 
 
 
For crown rot, apply before 
the plants are infected to 
obtain satisfactory control. 
 
 
Soil Spray (band): 
Direct the spray to the base of the 
plants and cover 6-8 inches of the 
soil on either side of the plants. 
 
Incorporate mechanically or 
sprinkler-irrigate to move 
Mefenoxam 2E into the root zone. 
 
Shank Application: Apply in 
liquid fertilizer, shanked in as a 
banded treatment to either side of 
the plant. 
 
Injection (drip irrigation): Inject 
Mefenoxam 2E into the irrigation 
water. 
 
Suppression: 
Crown rot 
 (Phytophthora 
capsici) 
 Transplant 
water: 
 
0.50 – 1.0 pt 
/100 – 200 
gal water/A 
 
 
In transplant water or 
immediately following 
planting. 
 
 
 
 
Apply in transplant water or 
immediately following planting via 
soil drench. 
 
Apply in at least 100 gallons of 
transplant water per acre.

36 
(0.125-0.25) 14-21 days after transplanting 
in fields with a history of 
Phytophthora capsici blight. 
In fields with a history of 
Phytophthora capsici blight, make 
the follow up application by drip 
irrigation. 
TOMATO ONLY 
 
Damping off 
(Pythium spp.) 
 
Fruit rot 
(Phytophthora 
spp.) 
 
Root rot 
(Pythium spp.) 
2.0 – 4.0 
pt/A 
(0.5-1.0) 
At planting Soil Spray (broadcast or band): 
Apply in water or liquid fertilizer. 
 
For banded applications, use a 7-
inch band. To calculate the rate as 
a band application, see Section 
4.1.1. 
 
2.0 pt/A 
(0.5) 
Subsequent applications: 
Following soil application at 
planting, make up to two 
applications 4-6 weeks apart. 
 
 
Soil Spray (broadcast or band) 
or Injection (drip irrigation): 
Apply as a directed soil surface 
spray under the vines or injected 
into the beds with water or liquid 
fertilizer. 
 
Make subsequent applications by 
drip irrigation according to the 
application timing schedule. 
 
 
For injected applications, base 
rate calculations on a 7-inch band. 
To calculate the rate as a band 
application, see Section 4.1.1. 
Resistance Management: 
 Refer to Section 3.2. 
Precautions: 
 Plants already infected with Phytophthora capsici cannot be cured with Mefenoxam 2E. 
 The foliar blight phase of Phytophthora cannot be cured with Mefenoxam 2E. 
 Application of Mefenoxam 2E may cause some yellowing of pepper leaves. 
 There is a risk of plant injury with transplant water application: 
o Crop injury is more likely when applied in less than 100 gallons/acre. Injury is temporary and 
typically disappears within three weeks. 
o Pre-mixing Mefenoxam 2E in a t ank separate from the transplant water source tank will help to 
prevent incompatibility with fertilizers or other pesticides in the transplant water solution. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 2.0 pt/A (equivalent to 0.5 lb ai/A mefenoxam) except for 
Tomato: 4.0 pt/A (equivalent to 1.0 lb ai/A mefenoxam) 
3) Minimum Application Interval: 30 days unless following transplant water application, then 14 
days; except for Tomato: 28 days 
4) Maximum Annual Application Rate: 6.0 pt/A/year (equivalent to 1.5 lb ai/A/year mefenoxam) 
a) DO NOT exceed 1.5 lb ai/A/year of soil-applied and 0.5 lb ai/A/year of foliar-applied mefenoxam- 
and metalaxyl-containing products. 
5) DO NOT make more than 3 applications at the maximum application rate per year except for 
Tomato: DO NOT make more than 2 applications at the maximum application rate per year OR 3 
applications at the minimum application rate per year. 
6) Pre-harvest Interval (PHI): 7 days

37 
 
 
 
7.15 Grapes 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Grapes 
Target Disease 
Rate 
(lb ai) Application Timing Use Directions 
Crown rot 
Root rot 
(Phytophthora 
spp.) 
7.2 pt/A 
(1.8) 
 
 
Drip Irrigation: 
1.0 – 2.0 fl 
oz/1000 gal 
water 
 
or 
 
 0.5 pt/1000 
linear feet of 
row 
Apply in the spring before 
plants start growing. 
 
Two additional applications 
may be made to coincide with 
periods most favorable for root 
rot development. 
 
 
Soil Spray (broadcast, band, or 
drip): Apply using sufficient water 
to provide uniform coverage. 
 
 
For banded applications, use a 3-
ft band at the base of the plants. 
 
Calculate the correct amount 
based on 7.2 pt/A using the 
instructions in Section 4.1.1. 
 
For drip irrigation, apply at 
the beginning of the growing 
season (bud break) or at 
transplanting. 
 
Two additional drip irrigation 
applications may be made at 
3-month intervals. 
 
Applications are not needed 
during the winter dormancy 
period. 
Injection (drip irrigation): Inject 
Mefenoxam 2E into the irrigation 
water. 
Resistance Management: 
 Refer to Section 3.2. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 7.2 pt/A (equivalent to 1.8 lb ai/A mefenoxam) 
3) Minimum Application Interval: 90 days 
4) Maximum Annual Application Rate: 21.6 pt/A/year (equivalent to 5.4 lb ai/A/year mefenoxam) 
a) DO NOT exceed 5.4 lb ai/A/year of soil-applied and 0.4 lb ai/A/year of foliar-applied mefenoxam- 
and metalaxyl-containing products. 
5) DO NOT make more than 3 applications at the maximum application rate per year. 
6) Pre-harvest Interval (PHI): 60 days

38 
 
7.16 Grass Forage, Fodder, and Hay, Crop Group 17 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Forage, fodder, stover, and hay of any grass, Gramineae/Poaceae family (either green or cured) 
except for sugarcane and those included in the cereal grains group, including: 
Bermudagrass 
Bromegrass 
Fescue 
Bluegrass 
Orchardgrass 
Sudangrass 
Reed Canarygrass 
Timothy 
Ryegrass 
Target Disease 
Rate 
pt/A 
(lb ai) Application Timing Use Directions 
Seedling diseases 
 (Pythium spp.) 
 
0.50 – 2.0 
(0.125-
0.5) 
At planting Soil Spray (broadcast): Apply as a 
broadcast soil surface spray. 
 
If the grass seed was previously treated 
with mefenoxam or metalaxyl as a seed 
dressing, use the 0.50-1.0 pt/A (0.125-0.25 
lb ai) rate. 
 
 
 Resistance Management: 
 Refer to Section 3.2. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 2.0 pt/A (equivalent to 0.5 lb ai/A mefenoxam) 
3) Minimum Application Interval: NA 
4) Maximum Annual Application Rate: 2.0 pt/A/year (equivalent to 0.5 lb ai/A/year mefenoxam) 
a) DO NOT exceed 0.50 lb ai/A/year of mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 1 application at the maximum application rate per year. 
6) DO NOT apply to range grasses. 
7) DO NOT graze, feed green forage, or cut hay for 60 days following application. 
8) Pre-harvest Interval (PHI): 60 days

39 
7.17 Herbs (fresh and dried), Crop Subgroup 19A 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Angelica, balm 
Basil 
Borage 
Burnet 
Chamomile 
Catnip 
Chervil (dried) 
Chive 
Chive, Chinese 
Clary 
Coriander (leaf) 
Costmary 
Culantro (leaf) 
Curry (leaf) 
Dillweed 
Horehound 
Hyssop 
Lavender 
Lemongrass 
Lovage (leaf) 
Marigold 
Marjoram 
Nasturtium 
Parsley (dried) 
Pennyroyal 
Rosemary 
Rue 
Sage 
Savory, summer and winter 
Sweet bay 
Tansy 
Tarragon 
Thyme 
Wintergreen 
Woodruff 
Wormwood 
Target Disease 
Rate 
pt/A 
(lb ai) Application Timing Use Directions 
Damping off 
 (Pythium spp.) 
 
2.0 – 4.0 
(0.5-1.0) 
Preplant incorporated Preplant Incorporated (broadcast or 
band): 
Apply in water or liquid fertilizer and 
mechanically incorporate in the top 2 
inches of soil. 
 
 
Soil Spray (broadcast or band): 
Apply in sufficient water to provide 
uniform coverage. 
 
For banded applications, use a 7-inch 
band. To calculate the rate as a band 
application, see Section 4.1.1. 
 
 Subsequent 
applications or 
established plantings 
Soil Spray (band): Apply as a soil-
directed spray 28 days after planting or 
after the first cutting. Direct the spray 
toward the base of the plants and cover 
6-8 inches on each side of the plants (12- 
to 16-inch band width/row). 
To calculate the rate as a band 
application, see Section 4.1.1. 
 
Resistance Management: 
 Refer to Section 3.2. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 4.0 pt/A (equivalent to 1.0 lb ai/A mefenoxam) 
3) Minimum Application Interval: 28 days 
4) Maximum Annual Application Rate: 8.0 pt/A/year (equivalent to 2.0 lb ai/A/year mefenoxam) 
a) DO NOT exceed 2.0 lb ai/A/year of soil-applied mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 2 applications at the maximum application rate per year. 
6) Pre-harvest Interval (PHI): 21 days

40 
 
7.18 Hops 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Hops 
Target Disease 
Rate 
pt/A 
(lb ai) Application Timing Use Directions 
Downy mildew 
 (Pseudoperonospora 
humuli) 
 
1.0 
(0.25) 
 
 
 
 
 
 
 
Soil Application: Apply 
after pruning but before 
training when shoots are 6 
inches or less. 
 
 
Foliar Application: At the 
first sign of a secondary 
infection (primary infection 
persists after the soil 
drench and/or there is 
evidence of foliar infection). 
 
Make up to two applications 
at least 14 days apart. 
Soil Application (drench or via 
drip/micro-sprinkler irrigation): 
Apply as a drench in water or liquid 
fertilizer to the soil over the crowns. 
 
 
Foliar Application: Apply by ground with 
a minimum of 50 gallons of water per acre. 
 
 
Mefenoxam 2E must be tank mixed with 
another fungicide (for example, a copper 
fungicide) labeled for downy mildew that 
has a different mode of action. 
Resistance Management: 
 Refer to Section 3.2. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 1.0 pt/A (equivalent to 0.25 lb ai/A mefenoxam) 
3) Minimum Application Interval: 
a) Soil: NA 
b) Foliar: 14 days 
4) Maximum Annual Application Rate: Soil: 1.0 pt/A/year (equivalent to 0.25 lb ai/A/year mefenoxam) 
Foliar: 2.0 pt/A/year (equivalent to 0.5 lb ai/A/year mefenoxam) 
a) DO NOT exceed 0.25 lb ai/A/year of soil-applied and 0.5 lb ai/A/year of foliar-applied mefenoxam- and 
metalaxyl-containing products. 
5) DO NOT make more than 1 soil-applied application and 2 foliar-applied applications at the maximum 
application rate per year. 
6) DO NOT apply foliar sprays of Mefenoxam 2E without a labeled tank-mix partner for downy mildew. 
7) Pre-harvest Interval (PHI): 45 days

41 
 
7.19 Leafy Greens, Crop Subgroup 4-16A 
Crops (including all cultivars, varieties, and/or hybrids of these) 
See Section 7.20 for separate Spinach directions. 
 
Amaranth, Chinese 
Amaranth, leafy 
Aster, Indian 
Blackjack 
Cat’s whiskers 
Cham-chwi 
Cham-na-mul 
Chervil, fresh leaves 
Chipilin 
Chrysanthemum, garland 
Cilantro, fresh leaves 
Corn salad 
Cosmos 
 
Dandelion, leaves 
Dang-gwi, leaves 
Dillweed 
Dock 
Dol-nam-mul 
Ebolo 
Endive 
Escarole 
Fameflower 
Feather cockscomb 
Good King Henry 
Huauzontle 
Jute, leaves 
 
Lettuce, bitter 
Lettuce, head 
Lettuce, leaf 
Orach 
Parsley, fresh leaves 
Plantain, buckhorn 
Primrose, English 
Purslane, garden 
Purslane, winter 
Radicchio 
Swiss chard 
Violet, Chinese, leaves 
Target Disease 
Rate 
(lb ai) Application Timing Use Directions 
Damping off 
(Pythium spp.) 
2.0 – 4.0 pt/A 
(0.5-1.0) 
Preplant incorporated 
 
 
 
 
 
At planting 
Preplant Incorporated (broadcast 
or band): 
Apply in water or liquid fertilizer and 
mechanically incorporate in the top 
2 inches of soil. 
 
Soil Spray (broadcast or band): 
Apply in water or liquid fertilizer at 
planting. 
 
 
For banded applications, use a 7-
inch band. To calculate the rate as 
a band application, see Section 
4.1.1. 
 
Make no more than one soil 
application. 
 Transplant 
water: 
 0.50 – 1.0 
pt/100-200 
gal water/A 
(0.125-0.25) 
 
At transplant or 
immediately following 
planting. 
 
Apply in transplant water or 
immediately following planting via 
soil drench. 
 
Apply in at least 100 gallons of 
transplant water per acre. 
LETTUCE, HEAD 
AND LEAF ONLY 
Downy mildew 
 (Bremia lactucae) 
 
0.25 – 0.5 
pt/A 
(0.063-0.125) 
Apply when conditions 
are favorable for disease 
but before infection on a 
14-day schedule. 
Foliar Spray (ground or air): 
Mefenoxam 2E must be used in a 
tank-mix with other fungicides 
registered for control of downy 
mildew.

42 
Apply with the full label rate of the 
tank-mix partner fungicide. 
 
Resistance Management: 
 Refer to Section 3.2. 
Precautions: 
 There is a risk of plant injury with transplant water application: 
o Crop injury is more likely when applied in less than 100 gallons/acre. Injury is temporary and 
typically disappears within three weeks. 
o Pre-mixing Mefenoxam 2E in a t ank separate from the transplant water source tank will help to 
prevent incompatibility with fertilizers or other pesticides in the transplant water solution. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 4.0 pt/A (equivalent to 1.0 lb ai/A mefenoxam) 
3) Minimum Application Interval: 
a) Soil: NA 
b) Foliar (Lettuce only): 14 days 
4) Maximum Annual Application Rate: Soil: 4.0 pt/A/year (equivalent to 1.0 lb ai/A/year mefenoxam) 
Foliar (Lettuce only): 1.6 pt/A/year (equivalent to 0.4 lb ai/A/year mefenoxam) 
a) DO NOT exceed 1.0 lb ai/A/year of soil-applied mefenoxam- and metalaxyl-containing 
products. 
b) For lettuce only, DO NOT exceed 1.0 lb ai/A/year of soil-applied and 0.4 lb ai/A/year of foliar-
applied mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 1 soil application per crop year. 
6) DO NOT apply foliar sprays of Mefenoxam 2E without a labeled tank-mix partner. 
7) DO NOT apply the Mefenoxam 2E mixture in fields where downy mildew is already established. 
8) For lettuce only, DO NOT make more than 4 foliar applications per crop. 
9) Pre-harvest Interval (PHI): 7 days

43 
 
7.20 Spinach 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Spinach 
Spinach, Malabar 
Spinach, New Zealand 
Spinach, Tanier 
 
 
Target Disease 
Rate 
(lb ai) Application Timing Use Directions 
Damping off 
(Pythium spp.) 
2.0 – 4.0 pt/A 
(0.5-1.0) 
Preplant incorporated 
 
 
 
 
 
 
 
At planting 
Preplant Incorporated (broadcast or 
band): 
Apply in water or liquid fertilizer and 
mechanically incorporate in the top 2 
inches of soil. 
 
 
 
Soil Spray (broadcast or band): 
Apply in water or liquid fertilizer at 
planting. 
 
For banded applications, use a 7-inch 
band. To calculate the rate as a band 
application, see Section 4.1.1. 
 
 
Make no more than one soil 
application. 
Transplant 
water: 
0.50-1.0 
pt/100-200 gal 
water/A 
(0.125-0.25) 
 
At transplant or 
immediately following 
planting. 
 
Apply in transplant water or 
immediately following planting via soil 
drench. 
 
Apply in at least 100 gallons of 
transplant water per acre. 
White rust 
 ( Albugo 
occidentalis) 
 
Downy mildew 
(Peronospora 
effusa and 
Peronospora 
farinosa) 
 
 
0.50 pt/A 
(0.125) 
21 days after planting 
or after the first 
cutting. 
 
A second application 
may be shanked in 
after the second 
cutting. 
 
Applications may be 
made on a 21-day 
interval. 
Shank in Mefenoxam 2E according to 
the application timing schedule. 
 
A total of 2 shanked applications may 
be made to spinach. 
Resistance Management: 
 Refer to Section 3.2. 
Precautions: 
 There is a risk of plant injury with transplant water application: 
o Crop injury is more likely when applied in less than 100 gallons/acre. Injury is temporary and 
typically disappears within three weeks. 
o Pre-mixing Mefenoxam 2E in a t ank separate from the transplant water source tank will help to 
prevent incompatibility with fertilizers or other pesticides in the transplant water solution.

44 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 4.0 pt/A (equivalent to 1.0 lb ai/A mefenoxam) 
3) Minimum Application Interval: 21 days 
4) Maximum Annual Application Rate: 5.6 pt/A/year (equivalent to 1.4 lb ai/A/year mefenoxam) 
a) DO NOT exceed 1.0 lb ai/A/year of soil-applied mefenoxam- and metalaxyl-containing 
products at planting followed by either: 
i. No more than 0.25 lb ai/A/year of post-planting shanked-in applications of 
mefenoxam- and metalaxyl-containing products or 
ii. No more than 0.4 lb ai/A/year of foliar-applied mefenoxam- and metalaxyl-
containing products 
5) DO NOT apply the Mefenoxam 2E mixture in fields where downy mildew is already established. 
6) DO NOT make more than 1 soil application and 2 shank applications per crop year. 
7) Pre-harvest Interval (PHI): 3 days only if soil application does not exceed 1.0 lb ai/A/year and 
foliar application does not exceed 0.25 lb ai/A/year of mefenoxam- and metalaxyl-containing 
products. Otherwise, the PHI is 21 days. 
 
 
7.21 Legume Vegetables, Crop Group 6-22 
 
Crops (including all cultivars, varieties, and/or hybrids of these) 
African yam bean 
American potato bean 
Bean (Lupinus spp.) 
including but not limited to: 
Adean lupin 
Blue lupin 
Grain lupin 
Sweet lupin 
White lupin 
White sweet lupin 
Yellow lupin 
Bean (Phaseolus spp.) 
including but not limited to: 
Black bean 
Cranberry bean 
Dry bean 
Field bean 
French bean 
Garden bean 
Great Northern bean 
Green bean 
Kidney bean 
Lima bean 
Navy bean 
Pink bean 
Pinto bean 
Red bean 
Runner bean 
Snap bean 
Tepary bean 
Wax bean 
Yellow bean 
Bean (Vigna spp.) 
including but not limited to: 
Adzuki bean 
Asparagus bean 
Blackeyed pea 
Catjang bean 
Chinese longbean 
Cowpea 
Crowder pea 
Moth bean 
Mung bean 
Rice bean 
Southern pea 
Urd bean 
Yardlong bean 
Pea (Pisum spp.) 
including but not limited to: 
Dry pea 
Dwarf pea 
 
English pea 
Field pea 
Garden pea 
Green pea 
Marrowfat pea 
Snap pea 
Snow pea 
Sugar snap pea 
Wrinkled pea 
Yellow pea 
 
Broad bean (fava bean) 
Chickpea (garbanzo bean) 
Goa bean (asparagus pea and 
winged bean) 
Grass pea 
Guar bean 
Horse gram 
Jackbean 
Lablab bean (hyacinth bean) 
Lentil 
Morama bean 
Pigeon pea 
Sword bean 
Vegetable soybean (edamame) 
Velvetbean 
Winged pea

45 
Target Disease 
Rate 
pt/A 
(lb ai) Application Timing Use Directions 
Damping off 
Root rot 
(Pythium spp.) 
1.0 – 2.0 
(0.25-0.5) 
Preplant incorporated 
 
 
 
 
 
At planting 
Preplant Incorporated (broadcast or 
band): 
Apply in water or liquid fertilizer and 
mechanically incorporate in the top 2 
inches of soil. 
 
Soil Spray (broadcast or band): 
Apply in water or liquid fertilizer at 
planting. 
 
 
For banded applications, use a 7-inch 
band. To calculate the rate as a band 
application, see Section 4.1.1. 
Resistance Management: 
 Refer to Section 3.2. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 2.0 pt/A (equivalent to 0.5 lb ai/A mefenoxam) 
3) Minimum Application Interval: NA 
4) Maximum Annual Application Rate: 2.0 pt/A/year (equivalent to 0.5 lb ai/A/year mefenoxam) 
a) DO NOT exceed 0.5 lb ai/A/year of soil-applied mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 1 application at the maximum application rate per year. 
6) Pre-harvest Interval (PHI): NA 
 
7.22 Succulent Shelled Beans, Crop Subgroup 6-22C 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Bean (Phaseolus spp.) including 
but not limited to: 
Lima bean 
Scarlet Runner bean 
Wax bean 
Bean (Vigna spp.) including but 
not limited to: 
Blackeyed pea 
Catjang bean 
Cowpea 
Crowder pea 
Moth bean 
Southern pea 
 
Bean (Lupinus spp.) including 
but not limited to: 
Andean lupin 
Blue lupin 
Grain lupin 
Sweet lupin 
White lupin 
White sweet lupin 
Yellow lupin 
 
Broad bean (fava bean) 
Jackbean 
Goa bean 
Lablab bean (hyacinth bean) 
Vegetable soybean (edamame) 
Velvetbean 
 
 
 
Target Disease 
Rate 
pt/A 
(lb ai) Application Timing Use Directions 
Downy mildew 
 (Phytophthora 
parasitica) 
0.25 – 0.4 
(0.063-0.1) 
Apply when conditions are 
favorable for disease but 
before infection on a 14-
day schedule. 
Foliar Spray (ground or air): 
Mefenoxam 2E must be used in a tank-mix 
with other fungicides registered for control 
of downy mildew.

46 
Apply with the full label rate of the tank-mix 
partner fungicide. 
Resistance Management: 
 Refer to Section 3.2. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 
a) Foliar: 0.4 pt/A (equivalent to 0.1 lb ai/A mefenoxam) 
3) Minimum Application Interval: 14 days 
4) Maximum Annual Application Rate: Foliar: 1.6 pt/A/year (equivalent to 0.4 lb ai/A/year mefenoxam) 
a) DO NOT exceed 0.5 lb ai/A/year of soil-applied and 0.4 lb ai/A/year of foliar-applied mefenoxam- 
and metalaxyl-containing products. 
5) DO NOT make more than 1 soil-applied application and 4 foliar-applied applications at the maximum 
application rate per year. 
6) For use only on succulent beans east of the Mississippi River. 
7) Pre-harvest Interval (PHI): 3 days 
 
7.23 Succulent Shelled Peas, Crop Subgroup 6-22D 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Chickpea 
Lentil 
Pigeon pea 
Pea (Pisum spp.) including but not limited to: 
English pea 
Garden pea 
Green pea 
Target Disease 
Rate 
pt/A 
(lb ai) Application Timing Use Directions 
Downy mildew 
 (Phytophthora 
parasitica) 
0.25 – 0.4 
(0.063-0.1) 
Apply when conditions are 
favorable for disease but 
before infection on a 14-
day schedule. 
Foliar Spray (ground or air): 
Ridomil Gold SL must be used in a tank-mix 
with other fungicides registered for control 
of downy mildew. 
 
Apply with the full label rate of the tank-mix 
partner fungicide. 
Resistance Management: 
 Refer to Section 3.2. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 
a) Foliar: 0.4 pt/A (equivalent to 0.1 lb ai/A mefenoxam) 
3) Minimum Application Interval: 14 days 
4) Maximum Annual Application Rate: Foliar: 1.6 pt/A/year (equivalent to 0.4 lb ai/A/year mefenoxam) 
a) DO NOT exceed 0.5 lb ai/A/year of soil-applied and 0.4 lb ai/A/year of foliar-applied mefenoxam- 
and metalaxyl-containing products. 
5) DO NOT make more than 1 soil-applied application and 4 foliar-applied applications at the maximum 
application rate per year. 
6) For use only on succulent beans east of the Mississippi River. 
7) Pre-harvest Interval (PHI): 3 days

47 
7.24 Peanut 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Peanut 
Target Disease 
Rate 
pt/A 
(lb ai) Application Timing Use Directions 
Pythium root rot 
 (Pythium spp.) 
 
0.50 
(0.125) 
At planting In-furrow Spray: 
Position the spray so the fungicide is 
mixed with the soil covering the seed. 
 
Avoid spraying the seed directly or 
crop injury may occur. 
 
To calculate the rate as an in-furrow 
application, see Section 4.1.2. 
 
Soil Spray (banded): 
Apply over the row. Use a 7-inch 
band. To calculate the rate as a band 
application, see Section 4.1.1. 
 
Pod rot 
 (Pythium spp.) 
1.0 – 2.0 
(0.25-
0.50) 
At pegging to early pod set Apply at early pod set as a soil-
directed spray or at pegging through 
foliar (overhead irrigation). 
Resistance Management: 
 Refer to Section 3.2. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 
a) Soil (at planting): 0.50 pt/A (equivalent to 0.125 lb ai/A mefenoxam) 
b) Foliar: 2.0 pt/A (equivalent to 0.5 lb ai/A mefenoxam) 
3) Minimum Application Interval: NA 
4) Maximum Annual Application Rate: Soil: 0.50 pt/A/year (equivalent to 0.125 lb ai/A/year 
mefenoxam) Foliar: 2.0 pt/A/year (equivalent to 0.50 lb ai/A/year mefenoxam) 
a) DO NOT exceed 0.125 lb ai/A/year of soil-applied and 0.50 lb ai/A/year of foliar-applied 
mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 1 soil-applied application and 1 soil-directed (foliar) application at the 
maximum application rate per year. 
6) Pre-harvest Interval (PHI): NA

48 
 
 
7.25 Pineapple, Crown Dip 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Pineapple 
Target Disease 
Rate 
pt 
(lb ai) Application Timing Use Directions 
Heart rot disease 
(Phytophthora 
spp.) 
1.0 – 2.0 
in 100 gal 
water 
(0.25-
0.50) 
Crown dip before planting The amount of dip solution per acre 
will depend on crown size, plant 
density, and dipping techniques. 
 
Use 75-100 gallons of the mixture per 
acre for dipping. 
Resistance Management: 
 Refer to Section 3.2. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 2.0 pt/100 gal water/A (equivalent to 0.5 lb ai/A mefenoxam) 
3) Minimum Application Interval: NA 
4) Maximum Annual Application Rate: 2.0 pt/100 gal water/A/year (equivalent to 0.5 lb ai/A/year 
mefenoxam) 
a) DO NOT exceed 0.5 lb ai/A/year of mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 1 application at the maximum application rate per year. 
6) If there is a crop failure within one year of planting treated crowns, DO NOT harvest plant material for 
animal feed. 
7) Pre-harvest Interval (PHI): NA 
 
7.26 Root and Tuber Vegetables 
7.26.1 CARROT 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Carrot 
Target Disease 
Rate 
pt/A 
(lb ai) Application Timing Use Directions 
Cavity spot 
Damping off 
Root dieback 
(Pythium spp.) 
1.0 – 2.6 
(0.25-0.65) 
Preplant incorporated 
 
 
 
 
 
At planting or prior to 
emergence 
Preplant Incorporated (broadcast 
or band): Apply in water or liquid 
fertilizer and mechanically incorporate 
in the top 2 inches of soil. 
 
 
Soil Spray (broadcast or band): 
Apply in water or liquid fertilizer. 
 
 
For banded applications, use a 7-inch 
band. To calculate the rate as a band 
application, see Section 4.1.1.

49 
 
NOTE: If post-planting applications 
are planned, see notes below for 
guidance on maximum rates for soil 
and foliar applications. 
 
 
0.5 – 2.0 
(0.125-0.5) 
 
 
 
Post-planting: Apply 
28-50 days after 
planting. Apply on a 
14- to 21-day interval. 
 
 
 
Soil-Directed Spray, Chemigation 
(Section 4.5), or Shank Application: 
All ground applications must be 
followed by irrigation with one inch of 
water to promote movement of 
product into the root zone. 
 
 
 
Directed spray: Make 
up to 4 applications 
beginning 40-60 days 
after planting. Apply on 
a 14- to 21-day interval. 
 
 
Soil-Directed Spray (broadcast or 
band): Apply as a spray directed to 
the base of the plant. Use sufficient 
water to provide uniform coverage of 
soil. 
 
For banded applications, use a 7-inch 
band. To calculate the rate as a band 
application, see Section 4.1.1. 
 
For irrigation, inject Mefenoxam 2E 
into the irrigation water. 
 
For best control of cavity spot, use a 
preventive disease control program 
that incorporates an at-planting or 
seed treatment use of mefenoxam 
followed by one or more additional 
applications. 
 
Resistance Management: 
 Refer to Section 3.2. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 2.6 pt/A (equivalent to 0.65 lb ai/A mefenoxam) 
3) Minimum Application Interval: 14 days 
4) Maximum Annual Application Rate: 5.6 pt/A/year (equivalent to 1.4 lb ai/A/year mefenoxam) 
a) DO NOT exceed a total of 1.4 lb ai/A/year of mefenoxam- and metalaxyl-containing products. 
b) DO NOT exceed 0.65 lb ai/A/year of soil-applied and 0.75 lb ai/A/year of foliar-applied metalaxyl- 
and mefenoxam-containing products. 
5) DO NOT make more than 1 soil-applied application and 1 soil-directed (foliar) application at the 
maximum application rate per year OR 4 soil-directed (foliar) applications not exceeding 0.35 lb 
ai/A/application. 
6) DO NOT use a soil application if a seed treatment containing mefenoxam or metalaxyl is used. 
7) Pre-harvest Interval (PHI): 7 days

50 
 
7.26.2 GINSENG 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Ginseng 
Target Disease 
Rate 
pt/A 
(lb ai) Application Timing Use Directions 
Phytophthora root 
rot 
(Phytophthora 
cactorum) 
1.5 
(0.375) 
Apply in the spring before 
plants start growing. 
For stand establishment, apply 
uniformly as a soil drench to the soil 
surface. Apply in 100-400 gallons of 
water per acre. 
 
Follow with additional applications of 
Ridomil Gold® GR (EPA Reg.#100-
798, mefenoxam). 
Resistance Management: 
 Refer to Section 3.2. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 1.5 pt/A (equivalent to 0.375 lb ai/A mefenoxam) 
3) Minimum Application Interval: NA 
4) Maximum Annual Application Rate: 1.5 pt/A/year (equivalent to 0.375 lb ai/A/year mefenoxam) 
a) DO NOT exceed 0.375 lb ai/A/year of soil-applied and 1.125 lb ai/A/year of foliar-applied 
mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 1 application of Mefenoxam 2E per year. 
6) Pre-harvest Interval (PHI): NA 
 
7.26.3 POTATO 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Potato 
Target Disease 
Rate 
(lb ai) Application Timing Use Directions 
Pink rot 
(Phytophthora 
erythroseptica) 
 
Pythium leak 
(Pythium spp.) 
 
Pythium seedling 
disease 
(Pythium spp.) 
0.84 fl 
oz/1000 
row ft 
 
Equiva-
lent to 
12.2 fl 
oz/A on 
36-inch 
row 
spacing 
(0.19) 
At planting 
 
 
 
 
 
 
 
 
A follow up application 
may be needed at tuber 
initiation. 
In-furrow spray: 
Apply directly over the seed pieces in-
furrow as a 6- to 8-inch band prior to 
row closure or use markout application 
method (incorporated). 
 
To calculate the rate as an in-furrow 
application, see Section 4.1.2. 
 
If needed, follow this in-furrow 
application with a Mefenoxam 2E 
prepack or tank-mix foliar application at 
tuber initiation: 
 
 When conditions are conducive for 
disease development. 
 When the variety is susceptible or 
moderately susceptible to pink 
rot/pythium leak.

51 
 In areas with a long growing 
season. 
 
Mefenoxam 2E may be impregnated on 
dry fertilizer or applied in combination 
with liquid fertilizers. 
 6.4 fl oz/A 
(0.1) 
Foliar Application: At 
tuber initiation when the 
largest tubers are the 
size in diameter of a 
nickel; this usually 
coincides with initiation of 
flowering. 
 
Make a second 
application 14 days later 
and, if the field has a 
history of storage rot 
problems, a third 
application 14 days after 
the second application. 
Broadcast or Soil-Directed (air, 
ground, or chemigation). 
 
If the field has a history of storage rot 
problems, make a third application. 
 
If foliar diseases are expected, then a 
tank-mix with a labeled rate of 
mancozeb or chlorothalonil products is 
required. 
 
Use in conjunction with other 
management practices including crop 
rotation and resistant varieties. 
Resistance Management: 
 Refer to Section 3.2. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 
a) Soil: 0.84 fl oz/1000 row ft (equivalent to 0.19 lb ai/A mefenoxam) 
b) Foliar: 6.4 fl oz/A (equivalent to 0.1 lb ai/A mefenoxam) 
3) Minimum Application Interval: 14 days 
4) Maximum Annual Application Rate: Soil: 0.84 fl oz/1000 row ft (equivalent to 0.19 lb ai/A/year 
mefenoxam) Foliar: 19.2 fl oz/A/year (equivalent to 0.3 lb ai/A/year mefenoxam) 
a) DO NOT exceed 0.34 lb ai/A/year of soil-applied and 0.40 lb ai/A/year of foliar-applied 
mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 1 soil-applied application and 3 foliar-applied applications at the maximum 
application rate per year. 
6) DO NOT use the “dribble” application method. 
7) Pre-harvest Interval (PHI): 14 days

52 
 
7.26.4 ROOT AND TUBER VEGETABLES, CROP GROUP 1 (EXCEPT CARROT, 
GINSENG, AND POTATO) 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Arracacha 
Arrowroot 
Artichoke, Chinese 
Artichoke, Jerusalem 
Beet, garden 
Burdock, edible 
Canna, edible 
Cassava, bitter 
Cassava, sweet 
Celeriac (celery root) 
Chayote (root) 
Chervil, turnip-rooted 
Chicory 
Chufa 
Dasheen (taro) 
Ginger 
Horseradish 
Leren 
Parsley, turnip-rooted 
Parsnip 
Radish 
Radish, oriental (daikon) 
Rutabaga 
Salsify (oyster plant) 
Salsify, black 
Salsify, Spanish 
Skirret 
Sugar Beet 
Sweet potato 
Tanier (cocoyam) 
Turmeric 
Turnip 
Yam bean (jicama, manoic pea) 
Yam, true 
Target Disease 
Rate 
pt/A 
(lb ai) Application Timing Use Directions 
Pythium root rot 
(Pythium spp.) 
Phytophthora root rot 
(Phytophthora spp.) 
 
2.0 – 4.0 
(0.5-1.0) 
Preplant incorporated 
 
 
 
 
 
 
 
 
At planting 
Preplant Incorporated (broadcast 
or band): 
Apply in water or liquid fertilizer and 
mechanically incorporate in the top 
2 inches of soil. Use sufficient 
water to provide uniform coverage 
of soil. 
 
 
Soil Spray (broadcast or band): 
Apply in water or liquid fertilizer at 
planting. 
 
 
For banded applications, use a 7-
inch band. To calculate the rate as 
a band application, see Section 
4.1.1. 
Resistance Management: 
 Refer to Section 3.2. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 4.0 pt/A (equivalent to 1.0 lb ai/A mefenoxam) 
3) Minimum Application Interval: NA 
4) Maximum Annual Application Rate: 4.0 pt/A/year (equivalent to 1.0 lb ai/A/year mefenoxam) 
a) DO NOT exceed 1.0 lb ai/A/year of mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 1 application at the maximum application rate per year. 
6) Pre-harvest Interval (PHI): NA

53 
7.27 Soybean 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Soybean 
Target Disease 
Rate 
(lb ai) Application Timing Use Directions 
Phytophthora root 
and stem rot 
 (Phytophthora 
megasperma) 
 
Pythium damping off 
(Pythium spp.) 
0.16-0.56 fl 
oz/1000 row 
ft 
(0.0025-
0.0087) 
At seeding 
 
In-furrow Spray: Apply in water or 
liquid fertilizer. Position the spray so 
the fungicide is mixed with the soil 
covering the seed. 
 
To calculate the rate as an in-furrow 
application, see Section 4.1.2. 
 
Use the higher specified rate for full-
season control. Use 0.16-0.30 fl oz 
(0.0025-0.0047 lb ai) for early- to mid-
season control. 
0.74-2.5 
pt/A 
(0.18-0.625) 
At seeding Soil Spray (broadcast or band): 
Apply in water or liquid fertilizer. Use 
the higher specified rate for full-season 
control. Use 0.74-1.50 pt (0.18-0.375 lb 
ai) for early- to mid-season control. 
 
For banded applications, use a 7-inch 
band. To calculate the rate as a band 
application, see Section 4.1.1. 
 
For best results, use soybean varieties 
that have some degree of resistance to 
the races of Phytophthora present in 
the field. 
 
Use the higher specified rate in areas 
with a history of heavy Phytophthora 
damage. 
Resistance Management: 
 Refer to Section 3.2. 
Precautions: 
 Avoid spraying the seed directly with an in-furrow spray or crop injury may occur. 
 Under heav y late-season Phytophthora pressure, Mefenoxam 2E may not provide complete control. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 2.5 pt/A (equivalent to 0.625 lb ai/A mefenoxam) 
3) Minimum Application Interval: NA 
4) Maximum Annual Application Rate: 2.5 pt/A/year (equivalent to 0.625 lb ai/A/year mefenoxam) 
a) DO NOT exceed 0.625 lb ai/A/year of mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 1 application at the maximum application rate per year. 
6) Pre-harvest Interval (PHI): NA

54 
7.28 Celtuce 
Crops (including cultivars, varieties, and/or hybrids of these) 
Celtuce 
Target Diseases Rate 
(lb ai) Application Timing Use Directions 
Damping off 
 ( Pythium spp.) 
 
2.0 – 4.0 pt/A 
(0.50-1.0) 
Preplant incorporated 
 
 
 
 
 
 
At planting 
Preplant Incorporated (broadcast or 
band): 
Apply in water or liquid fertilizer and 
mechanically incorporate in the top 2 
inches of soil. 
 
 
Soil Spray (broadcast or band): 
Apply in water or liquid fertilizer at 
planting. 
 
For banded applications, use a 7-inch 
band. To calculate the rate as a band 
application, see Section 4.1.1. 
 
Transplant 
water: 
 
0.50-1.0 pt/100-
200 gal water/A 
 
(0.125-0.25) 
At transplant or 
immediately following 
planting 
 
Apply in transplant water or 
immediately following planting via soil 
drench. 
 
Apply in at least 100 gallons of 
transplant water per acre. 
Resistance Management: 
 Refer to Section 3.2. 
Precautions: 
 There is a risk of plant injury with transplant water application: 
o Crop injury is more likely when applied in less t han 100 gallons/acre. Injury is temporary and typically 
disappears within three weeks. 
o Pre-mixing Mefenoxam 2E in a tank separate from the transplant water source tank will help to prevent 
incompatibility with fertilizers or other pesticides in the transplant water solution. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 4.0 pt/A (equivalent to 1.0 lb ai/A mefenoxam) 
3) Minimum Application Interval: NA 
4) Maximum Annual Application Rate: 4.0 pt/A/year (equivalent to 1.0 lb ai/A/year mefenoxam) 
a) DO NOT exceed 1.0 lb ai/A/year of soil-applied mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 1 application at the maximum application rate per year. 
6) Pre-harvest Interval (PHI): 7 days

55 
 
7.29 Fennel 
Crops (including cultivars, varieties, and/or hybrids of these) 
Fennel, Florence, fresh leaves and stalk 
Target Diseases Rate 
(lb ai) Application Timing Use Directions 
Damping off 
 ( Pythium spp.) 
 
2.0 – 4.0 pt/A 
(0.50-1.0) 
Preplant incorporated 
 
 
 
 
 
 
At planting 
Preplant Incorporated (broadcast or 
band): 
Apply in water or liquid fertilizer and 
mechanically incorporate in the top 2 
inches of soil. 
 
 
Soil Spray (broadcast or band): 
Apply in water or liquid fertilizer at 
planting. 
 
For banded applications, use a 7-inch 
band. To calculate the rate as a band 
application, see Section 4.1.1. 
 
Transplant 
water: 
 
0.50-1.0 pt/100-
200 gal water/A 
 
(0.125-0.25) 
At transplant or 
immediately following 
planting 
 
Apply in transplant water or 
immediately following planting via soil 
drench. 
 
Apply in at least 100 gallons of 
transplant water per acre. 
Resistance Management: 
 Refer to Section 3.2. 
Precautions: 
 There is a risk of plant injury with transplant water application: 
o Crop injury is more likely when applied in less t han 100 gallons/acre. Injury is temporary and typically 
disappears within three weeks. 
o Pre-mixing Mefenoxam 2E in a tank separate from the transplant water source tank will help to prevent 
incompatibility with fertilizers or other pesticides in the transplant water solution. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 4.0 pt/A (equivalent to 1.0 lb ai/A mefenoxam) 
3) Minimum Application Interval: NA 
4) Maximum Annual Application Rate: 4.0 pt/A/year (equivalent to 1.0 lb ai/A/year mefenoxam) 
a) DO NOT exceed 1.0 lb ai/A/year of soil-applied mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 1 application at the maximum application rate per year. 
6) Pre-harvest Interval (PHI): 7 days

56 
 
7.30 Kohlrabi 
Crops (including cultivars, varieties, and/or hybrids of these) 
Kohlrabi 
Target Diseases 
Rate 
pt/A 
(lb ai) 
Application Timing Use Directions 
Basal stem rot 
(Phytophthora 
spp.) 
 
 
 
2.0 – 4.0 
(0.50-1.0) 
 
Preplant incorporated 
 
 
 
 
 
At Planting 
Preplant Incorporated (broadcast or 
band): Apply in water or liquid fertilizer 
and incorporate in the top 2 inches of 
soil. 
 
 
Soil Spray (broadcast or band): 
Apply in water or liquid fertilizer at 
planting. 
 
For banded applications, use a 7-inch 
band. To calculate the rate as a band 
application, see Section 4.1.1. 
 
Injection (drip irrigation): Inject 
Mefenoxam 2E into the irrigation water 
at the labeled rates. 
 
Damping off 
(Pythium spp.) 
0.50 – 1.0 
(0.125-0.25) 
Preplant incorporated Preplant Incorporated (broadcast or 
band): 
Apply in water or liquid fertilizer and 
incorporate in the top 2 inches of soil. 
 
For banded applications, use a 7-inch 
band. To calculate the rate as a band 
application, see Section 4.1.1. 
 
Downy mildew 
 ( Peronospora 
parasitica) 
 
0.25 – 0.50 
(0.063-0.125) 
Apply when conditions are 
favorable for disease but 
before infection on a 14-
day schedule. 
 
Foliar Spray (ground or air): 
Mefenoxam 2E must be used in a 
tank-mix with other fungicides 
registered for control of downy mildew. 
Apply with the full label rate of the 
tank-mix partner fungicide. 
 
 
 
Resistance Management: 
 Refer to Section 3.2. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 
a) Soil: 4.0 pt/A (equivalent to 1.0 lb ai/A mefenoxam) 
b) Foliar: 0.5 pt/A (equivalent to 0.125 lb ai/A mefenoxam) 
3) Minimum Application Interval: 
a) Soil: NA 
b) Foliar: 14 days

57 
4) Maximum Annual Application Rate: Soil: 4.0 pt/A/year (equivalent to 1.0 lb ai/A/year mefenoxam) 
Foliar: 2.0 pt/A/year (equivalent to 0.5 lb ai/A/year mefenoxam) 
a) DO NOT exceed 1.0 lb ai/A/year of soil-applied and 0.5 lb ai/A/year of foliar-applied mefenoxam- and 
metalaxyl-containing products. 
5) DO NOT make more than 1 soil-applied application at the maximum application rate per year. 
6) DO NOT make more than 4 foliar-applied applications at the maximum application rate per year. 
7) DO NOT apply foliar sprays of Mefenoxam 2E without a labeled tank-mix partner. 
8) DO NOT apply the Mefenoxam 2E mixture in fields where downy mildew is already established. 
9) Pre-harvest Interval (PHI): 7 days 
 
7.31 Leaf Petiole Vegetables, Crop Subgroup 22B 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Cardoon 
Celery 
Celery, Chinese 
Fuki 
Rhubarb 
Udo 
Zuiki 
Target Disease 
Rate 
(lb ai) Application Timing Use Directions 
Damping off 
(Pythium spp.) 
2.0 – 4.0 pt/A 
(0.50-1.0) 
Preplant incorporated 
 
 
 
 
 
 
At planting 
Preplant Incorporated (broadcast 
or band): 
Apply in water or liquid fertilizer and 
incorporate in the top 2 inches of 
soil. 
 
 
Soil Spray (broadcast or band): 
Apply in water or liquid fertilizer at 
planting. 
 
For banded applications, use a 7-
inch band. To calculate the rate as 
a band application, see Section 
4.1.1. 
Transplant water: 
 
0.50-1.0 pt/100-
200 gal water/A 
 
(0.125-0.25) 
At transplant or 
immediately following 
planting 
 
Apply in transplant water or 
immediately following planting via 
soil drench. 
 
Apply in at least 100 gallons of 
transplant water per acre. 
Resistance Management: 
 Refer to Section 3.2. 
Precautions: 
 There is a risk of plant injury with transplant water application: 
o Crop injury is more likely when applied in less than 100 gallons/acre. Injury is temporary and 
typically disappears within three weeks. 
o Pre-mixing Mefenoxam 2E in a t ank separate from the transplant water source tank will help to 
prevent incompatibility with fertilizers or other pesticides in the transplant water solution. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 4.0 pt/A (equivalent to 1.0 lb ai/A mefenoxam) 
3) Minimum Application Interval: NA 
4) Maximum Annual Application Rate: 4.0 pt/A/year (equivalent to 1.0 lb ai/A/year mefenoxam) 
a) DO NOT exceed 1.0 lb ai/A/year of soil-applied mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 1 soil-applied application at the maximum application rate per year.

58 
6) Pre-harvest Interval (PHI): NA 
 
7.32 Stalk and Stem Vegetables, Crop Subgroup 22A 
Crops (including cultivars, varieties, and/or hybrids of these) 
See Sections 7.28, 7.29, and 7.30 for separate Celtuce, Fennel, and Kohlrabi directions, respectively. 
Agave 
Aloe vera 
Asparagus 
Bamboo shoots 
Fern, edible, fiddlehead 
Kale, sea 
Palm hearts 
Prickly pear, pads 
Prickly pear, Texas, pads 
 
Target Diseases 
Rate 
pt/A 
(lb ai) 
Application Timing Use Directions 
Crown rot 
Spear rot 
(Phytophthora spp.) 
2.0 
(0.50) 
Cutting beds: Apply 30 to 
60 days before the first 
cutting. 
 
Apply again just before the 
beginning of harvest. 
 
New plantings: Apply 
after planting seedlings or 
after covering one-year old 
crowns. 
Soil Spray (broadcast or band): 
Apply as a soil spray (broadcast 
or band). 
 
To calculate the rate as a band 
application, see Section 4.1.1. 
Resistance Management: 
 Refer to Section 3.2. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 2.0 pt/A (equivalent to 0.5 lb ai/A mefenoxam) 
3) Minimum Application Interval: 30 days 
4) Maximum Annual Application Rate: 4.0 pt/A/year (equivalent to 1.0 lb ai/A/year mefenoxam) 
a) DO NOT exceed 1.0 lb ai/A/year of soil-applied mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 2 applications at the maximum application rate per year. 
6) Pre-harvest Interval (PHI): 1 day

59 
 
7.33 Stone Fruits, Crop Group 12 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Apricot 
Cherry, sweet 
Cherry, tart 
Nectarine 
Peach 
Plum 
Plum, Chickasaw 
Plum, Damson 
Plum, Japanese 
Plumcot 
Prune 
Target Disease 
Rate 
(lb ai) Application Timing Use Directions 
Collar rot 
Crown rot 
Root rot 
(Phytophthora 
spp.) 
 
8.0 pt/A 
(2.0) 
 
or 
 
3.0 fl oz/1000 
sq ft 
Two weeks after planting 
(new plantings) or in the 
spring before growth begins 
(established plantings). 
 
Additional applications may 
be made at 2- to 3-month 
intervals, depending on 
disease pressure. 
 
 
Apply before symptoms 
appear. 
Soil Spray (broadcast, band, or 
irrigation): 
Apply to soil beneath the tree canopy 
or apply through irrigation water 
(micro-sprinkler or drip) to cover the 
root zone. 
 
 
For intensive plantings (2-3 times the 
normal planting rate), apply on a per 
area basis (1,000 sq ft). 
 
 
To calculate the rate as a band 
application, see Section 4.1.1. 
Resistance Management: 
 Refer to Section 3.2. 
Precaution: 
 Mefenoxam 2E will not revitalize trees showing moderate to severe disease symptoms. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 8.0 pt/A (equivalent to 2.0 lb ai/A mefenoxam) 
3) Minimum Application Interval: 60 days 
4) Maximum Annual Application Rate: 24.0 pt/A/year (equivalent to 6.0 lb ai/A/year mefenoxam) 
a) DO NOT exceed 6.0 lb ai/A/year of soil-applied mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 3 applications per year. 
6) DO NOT concentrate spray around tree trunks. 
7) DO NOT apply to trees under stress. 
8) In CA, DO NOT apply to newly planted trees within 45 days of planting. On some varieties, chlorosis may 
occur on leaf margins. 
9) DO NOT graze livestock in treated areas. 
10) DO NOT graze or feed cover crops grown in treated orchards. 
11) Pre-harvest Interval (PHI): 0 days

60 
 
7.34 Tobacco 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Tobacco 
Target Disease 
Rate 
(lb ai) Application Timing Use Directions 
Damping off 
(Pythium spp.) 
 
1.0 – 2.0 pt/A 
(0.25-0.5) 
 
or 
 
0.50 – 1.0 fl 
oz/150 sq yd 
Preplanting or at time of 
planting 
Soil Spray (broadcast): Apply as a 
preplant soil application before or at 
time of planting. Use the higher 
specified application rate on 
broadleaf tobacco. 
 
Use 65 gallons of water per acre (2 
gallons water/150 sq yd). 
 
Move into soil as described in 
Section 4.3. 
Blue mold 
(Peronospora 
tabacina) 
 
Broadcast 
1.0 – 2.0 pt/A 
(0.25-0.5) 
 
For no-till 
tobacco: 
1.0 – 2.0 pt/A 
(0.25-0.5) 
Prior to transplanting Soil Spray (broadcast): Apply as a 
broadcast soil application and 
incorporate in the top 2-4 inches of 
soil before forming beds. For 
additional control, make a second 
application at layby or at the last 
cultivation. 
 
Use the lower specified rate for low 
disease pressure or early-season 
control. 
 
Use the higher specified rate for high 
disease pressure, extended control, 
and on burley and other tobacco 
types other than flue-cured. 
 
1.0 pt/A 
(0.25) 
 
For no-till 
tobacco: 
1.0 – 2.0 pt/A 
(0.25-0.5) 
 
 
Layby or Last cultivation 
 
Soil Spray (band): Position the 
nozzles so the spray is deposited 
under the plants and is covered by 
the soil in cultivation. 
 
To calculate the rate as a band 
application, see Section 4.1.1. 
Black shank 
(Phytophthora 
parasitica var. 
nicotianae) 
Broadcast 
2.0 – 6.0 pt/A 
(0.5-1.5) 
 
For no-till 
tobacco: 
1.0 – 2.0 pt/A 
(0.25-0.5) 
 
 
 
 
Prior to transplant 
 
Make at least one 
subsequent application of 
Mefenoxam 2E at first 
cultivation and/or layby if 
necessary. 
 
Soil Spray (broadcast): Apply to 
the soil within a week of planting and 
incorporate in the top 2-4 inches of 
soil. Use the higher specified rate if 
disease epidemic is expected to be 
severe. 
 
In FL and GA, use 6.0 pt/A (1.5 lb ai) 
where black shank is severe. 
 
Move into soil as described in 
Section 4.3.

61 
 
 
Transplant 
water: 
0.50 – 1.0 pt 
/200 gal water 
 
(0.125-0.25) 
 
 
At transplant (followed by 
additional application at first 
cultivation or layby). 
 
 
 
 
 
 
 
 
 
Transplant water: Apply in 
transplant furrow while planting 
tobacco seedlings. Apply 0.50-1.0 
pt (0.125-0.25 lb ai) in at least 200 
gallons of transplant water per acre. 
Use the highest specified rate if the 
disease epidemic is expected to be 
severe. 
 
Pre-mixing Mefenoxam 2E in a tank 
separate from the transplant water 
source tank will help to prevent 
incompatibility with fertilizers or other 
pesticides in the transplant water 
solution. 
 
 
 2.0 – 4.0 pt/A 
(0.5-1.0) 
 
 
For no-till 
tobacco: 
1.0 – 2.0 pt/A 
(0.25-0.5) 
First Cultivation and/or 
layby 
Soil Spray (broadcast or band): 
Position the nozzles so the spray is 
deposited under the plants and 
covered with soil by the cultivator. 
To calculate the rate as a band 
application, see Section 4.1.1. 
Apply preventatively for effective 
black shank control. If black shank is 
expected early in the season, apply 
as near as possible to transplanting 
followed by sequential application. 
Consult local extension bulletins for 
additional use directions. 
 
For best results against black shank, 
use tobacco varieties that have high 
resistance to black shank and 
practice crop rotation. 
 
In fields with a history of severe 
black shank, use the highest 
specified rate and plant variety 
resistant to the race of Phytophthora 
present (Burley L8 hybrids are 
resistant to only Phytophthora Race 
0). 
 
 
 
 
Resistance Management: 
 Refer to Section 3.2.

62 
Precautions: 
 There is a risk of plant injury with transplant water application, especially when applied in less than 
200 gallons of carrier volume per acre. Crop injury is more likely when applied in less than 100 
gallons/acre. Injury is temporary and typically disappears within three weeks. 
 Failure to adequately control nematodes in fields treated with Mefenoxam 2E may result in poor 
control of black shank. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 6.0 pt/A (equivalent to 1.5 lb ai/A mefenoxam) 
3) Minimum Application Interval: 14 days 
4) Maximum Annual Application Rate: 6.0 pt/A/year (equivalent to 1.5 lb ai/A/year mefenoxam) 
a) DO NOT exceed 1.5 lb ai/A/year of mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 1 application at the maximum application rate per year OR 3 applications at 
the minimum application rate. 
6) DO NOT use in high black shank areas on highly susceptible flue-cured varieties. 
7) DO NOT use Mefenoxam 2E for black shank control in PA. 
8) DO NOT apply to stressed seedlings or during hot and dry conditions due to injury potential. 
9) Pre-harvest Interval (PHI): NA

63 
 
 
7.35 Tree Nuts, Crop Group 14-12 
Crops (including all cultivars, varieties, and/or hybrids of these) 
African nut-tree 
Almond 
Beechnut 
Brazil nut 
Brazilian pine 
Bunya 
Bur oak 
Butternut 
Cajou nut 
Candlenut 
Cashew 
Chestnut 
Chinquapin 
Coconut 
Coquito nut 
Dika nut 
Ginkgo 
Guiana chestnut 
Hazelnut (Filbert) 
Heartnut 
Hickory nut 
Japanese horse-
chestnut 
Macadamia nut 
Mongongo nut 
Monkey-pot 
Monkey puzzle nut 
Okari nut 
Pachira nut 
Peach palm nut 
Pecan 
Pequi nut 
Pili nut 
Pine nut 
Pistachio 
Sapucaia nut 
Tropical almond 
Walnut, black 
Walnut, English 
Yellowhorn 
Target Disease 
Rate 
(lb ai) Application Timing Use Directions 
Collar rot 
Crown rot 
Root rot 
(Phytophthora spp.) 
 
8.0 pt/A 
(2.0) 
 
or 
 
3.0 fl 
oz/1000 
sq ft 
2 weeks after planting (new 
plantings) or in the spring 
before growth begins 
(established plantings). 
 
Additional applications may be 
made at 2- to 3-month intervals, 
depending on disease 
pressure. 
 
 
Apply before symptoms appear. 
Soil Spray (broadcast, band, or 
irrigation): 
Apply to soil beneath the tree or apply 
through irrigation water (micro-sprinkler 
or drip) to cover the root zone. 
 
For intensive plantings (2-3 times the 
normal planting rate), apply on a per 
area basis (1,000 sq ft). 
 
To calculate the rate as a band 
application, see Section 4.1.1. 
Resistance Management: 
 Refer to Section 3.2. 
Precaution: 
 Mefenoxam 2E will not revitalize trees showing moderate to severe disease symptoms. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 8.0 pt/A (equivalent to 2.0 lb ai/A mefenoxam) 
3) Minimum Application Interval: 60 days 
4) Maximum Annual Application Rate: 24.0 pt/A/year (equivalent to 6.0 lb ai/A/year mefenoxam) 
a) DO NOT exceed 6.0 lb ai/A/year of soil-applied mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 3 applications per year. 
6) DO NOT concentrate spray around tree trunks. 
7) DO NOT apply to trees under stress. 
8) In CA, DO NOT apply to newly planted trees within 45 days of planting. On some varieties, chlorosis may 
occur on leaf margins. 
9) DO NOT graze livestock in treated areas. 
10) DO NOT graze or feed cover crops grown in treated orchards. 
11) Pre-harvest Interval (PHI): 30 days

64 
7.36 Tropical and Subtropical Fruit 
7.36.1 MEDIUM TO LARGE FRUIT, SMOOTH PEEL 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Canistel 
Mango 
Papaya 
 
Sapote, black 
Star apple 
Target Disease 
Rate 
pt/A 
(lb ai) Application Timing Use Directions 
Damping off 
(Pythium spp.) 
Root rot 
(Phytophthora 
spp.) 
 
3.0 – 6.0 
(0.75-1.5) 
Two applications may be 
made per season. 
 
Make the first application 
after transplanting or in the 
spring at root growth flush. 
 
Make a second application at 
least 1 day before harvest. 
Soil Drench: 
Add Mefenoxam 2E to water or a liquid 
fertilizer solution. Apply this solution to 
the base of the plants to deliver 
approximately 5 gallons per plant. 
 
Resistance Management: 
 Refer to Section 3.2. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 6.0 pt/A (equivalent to 1.5 lb ai/A mefenoxam) 
3) Minimum Application Interval: 90 days 
4) Maximum Annual Application Rate: 12.0 pt/A/year (equivalent to 3.0 lb ai/A/year mefenoxam) 
a) DO NOT exceed 3.0 lb ai/A/year of mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 2 applications per year. 
6) Pre-harvest Interval (PHI): 1 day 
 
7.36.2 MEDIUM TO LARGE FRUIT, ROUGH OR HAIRY PEEL 
Crops (including all cultivars, varieties, and/or hybrids of these) 
Atemoya 
Biriba 
Cherimoya 
Custard apple 
Ilama 
Sapodilla 
Sapote, mamey 
Starfruit 
Soursop 
Sugar apple 
Target Disease 
Rate 
pt/A 
(lb ai) Application Timing Use Directions 
Crown rot 
Damping off 
Pythium root rot 
(Pythium spp.) 
Crown rot 
Phytophthora root rot 
(Phytophthora spp.) 
 
3.0 – 6.0 
(0.75-1.5) 
Two applications may be 
made per season. 
 
Make the first application 
after transplanting or in the 
spring at root growth flush. 
 
Make a second application 
at least 30 day before 
harvest. 
Soil Drench: 
Add Mefenoxam 2E to water or a liquid 
fertilizer solution. Make applications to 
the soil surface under the canopy of the 
trees delivering approximately 5 gallons 
per plant.

65 
Resistance Management: 
 Refer to Section 3.2. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 6.0 pt/A (equivalent to 1.5 lb ai/A mefenoxam) 
3) Minimum Application Interval: 90 days 
4) Maximum Annual Application Rate: 12.0 pt/A/year (equivalent to 3.0 lb ai/A/year mefenoxam) 
a) DO NOT exceed 3.0 lb ai/A/year of mefenoxam- and metalaxyl-containing products. 
5) DO NOT make more than 2 applications per year. 
6) Pre-harvest Interval (PHI): 30 days 
 
7.37 Wasabi 
 
 
Crops (Including all cultivars, varieties, and/or hybrids of these) 
Wasabi (greenhouse) 
Target 
Disease 
Rate 
(lb ai) 
Application Timing Use Directions 
Root rot 
(Pythium spp.) 
1.0 – 3.0 
pt/A 
(0.25-0.75) 
Equivalent 
to 0.0012 – 
0.014 lb 
ai/ft3 
Make the first 
application prior to 
disease onset and 
subsequent applications 
on a 7-day interval. 
Greenhouse foliar mist application only: 
Apply only via automatic foliar misting 
system in 400-1500 gal/A. 
DO NOT apply more than 2 sequential 
applications of Mefenoxam 2E or other 
Group 4 fungicides before alternating with 
a fungicide that is not in Group 4. 
Resistance Management: 
 Refer to Section 3.2. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 3.0 pt/A (equivalent to 0.75 lb ai/A mefenoxam) 
3) Minimum Application Interval: 7 days 
4) Maximum Annual Application Rate: 18.0 pt/A (equivalent to 4.5 lb ai/A/year mefenoxam) 
a) DO NOT exceed 4.5 lb ai/A/year of mefenoxam- and metalaxyl-containing products. 
5) Applications may only be made via automatic foliar misting system. No workers or handlers may be 
present in the greenhouse during application. 
6) DO NOT make more than 6 applications per year. 
7) Pre-Harvest Interval (PHI): 7 days

66 
 
 
8.0 STORAGE AND DISPOSAL 
Storage and Disposal 
DO NOT contaminate water, food, or feed by storage or disposal. 
 
Pesticide Storage 
 DO NOT use or store near heat or open flame. Store in original containers only. Keep 
container closed when not in use. DO NOT store near food or feed. In case of spill on floor 
or paved surfaces, mop and remove to chemical waste storage area until proper disposal can 
be made if product cannot be used according to label. 
 
 
Pesticide Disposal 
Pesticide wastes are acutely toxic. Improper disposal of excess pesticide, spray mixture, or 
rinsate is a violation of federal law. If these wastes cannot be disposed of by use according 
to label instructions, contact your State Pesticide or Environmental Control Agency, or the 
Hazardous Waste representative at the nearest EPA Regional Office. 
 
Container Handling [(less than or equal to 5 gallons)] 
Non-refillable container. DO NOT reuse or refill this container. Triple rinse container (or 
equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents 
into application equipment or a mix tank and drain for 10 seconds after the flow begins to 
drip. Fill the container ¼ full with water and recap. Shake for 10 seconds. Pour rinsate into 
application equipment or a mix tank or store rinsate for later use or disposal. Drain for 10 
seconds after the flow begins to drip. Repeat this procedure two more times. Then offer for 
recycling (if available), or puncture and dispose of in a sanitary landfill, or by other 
procedures approved by state and local authorities. 
 
Container Handling [(greater than 5 gallons)] 
Non-refillable container. DO NOT reuse or refill this container . Triple rinse container (or 
equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents into 
application equipment or a mix tank. Fill the container ¼ full with water. Replace and tighten 
closures. Tip container on its side and roll it back and forth, ensuring at least one complete 
revolution, for 30 seconds. Stand the contai ner on its end and tip it back and forth several 
times. Turn the container over onto its other end and tip it back and forth several times. Empty 
the rinsate into application equipment or a mix tank or store rinsat e for later use or disposal. 
Repeat this procedure two more times. Then offer for recycling (if available), or puncture and 
dispose of in a sanitary landfill or by other procedures approved by state and local authorities. 
 
Container Handling [(greater than 5 gallons)] 
Refillable container. Refill this container with pesticide only. DO NOT reuse this container 
for any other purpose. Cleaning the container befor e final disposal is the responsibility of the

67 
person disposing of the container. Cleaning before refilling is the responsibility of the person 
refilling. To clean container before final dis posal, empty the remaining contents from this 
container into application equipment or mix tank. Fill the container abo ut 10 percent full with 
water. Agitate vigorously or recirculate wate r with the pump for 2 minutes. Pour or pump 
rinsate into application equipment or rinsate collection system. Repeat this rinsing procedure 
two more times. Then offer for recycling (if available), or puncture and dispose of in a sanitary 
landfill or by other procedures approved by state and local authorities. 
 
 
CONTAINER IS NOT SAFE FOR FOOD, FEED, OR DRINKING WATER. 
 
9.0 CONDITIONS OF SALE AND LIMITATION OF WARRANTY 
AND LIABILITY 
 
NOTICE: Read the entire Directions for Use and Conditions of Sale and Limitation of 
Warranty and Liability before buying or using this product. If the terms are not acceptable, 
return the product at once, unopened, and the purchase price will be refunded. 
 
The Directions for Use of this product must be followed carefully. It is impossible to eliminate 
all risks inherently associated with the use of this product. Crop injury, ineffectiveness or 
other unintended consequences may result because of such factors as manner of use or 
application, weather or crop conditions, presence of other materials or other influencing 
factors in the use of the product, which are beyond the control of SYNGENTA CROP 
PROTECTION, LLC or Seller. To the extent permitted by applicable law, Buyer and User 
agree to hold SYNGENTA and Seller harmless for any claims relating to such factors. 
 
SYNGENTA warrants that this product conforms to the chemical description on the label and 
is reasonably fit for the purposes stated in the Directions for Use, subject to the inherent risks 
referred to above, when used in accordance with directions under normal use conditions. To 
the extent permitted by applicable law: (1) this warranty does not extend to the use of the 
product contrary to label instructions, or under conditions not reasonably foreseeable to or 
beyond the control of Seller or SYNGENTA, and (2) Buyer and User assume the risk of any 
such use. TO THE EXTENT PERMITTED BY APPLICABLE LAW, SYNGENTA MAKES NO 
WARRANTIES OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE 
NOR ANY OTHER EXPRESS OR IMPLIED WARRANTY EXCEPT AS WARRANTED BY 
THIS LABEL. 
 
To the extent permitted by applicable law, in no event shall SYNGENTA be liable for any 
incidental, consequential or special damages resulting from the use or handling of this 
product. TO THE EXTENT PERMITTED BY APPLICABLE LAW, THE EXCLUSIVE 
REMEDY OF THE USER OR BUYER, AND THE EXCLUSIVE LIABILITY OF SYNGENTA 
AND SELLER FOR ANY AND ALL CLAIMS, LOSSES, INJURIES OR DAMAGES 
(INCLUDING CLAIMS BASED ON BREACH OF WARRANTY, CONTRACT, 
NEGLIGENCE, TORT, STRICT LIABILITY OR OTHERWISE) RESULTING FROM THE 
USE OR HANDLING OF THIS PRODUCT, SHALL BE THE RETURN OF THE PURCHASE

68 
PRICE OF THE PRODUCT OR, AT THE ELECTION OF SYNGENTA OR SELLER, THE 
REPLACEMENT OF THE PRODUCT. 
 
SYNGENTA and Seller offer this product, and Buyer and User accept it, subject to the 
foregoing Conditions of Sale and Limitation of Warranty and Liability, which may not be 
modified except by written agreement signed by a duly authorized representative of 
SYNGENTA. 
 
 
10.0 APPENDIX 
10.1 [Optional] Mefenoxam 2E Use Summary Table 
[Start of Optional Text] 
IMPORTANT: The table below is a summary of the Crop Use Directions for Mefenoxam 2E. 
However, it is important for the user to read and follow the complete instructions contained 
within this label. 
 
Crop or Crop 
Group/Subgroup with 
examples 
Maximum Single 
Application Rate 
(lb ai/A) 
Maximum 
Annual 
Application Rate 
(lb ai/A/year) 
Minimum 
Application 
Interval 
(days) 
Pre-Harvest 
Interval (PHI, 
days) 
Alfalfa 0.25 
 
0.25 NA 60 
Apple 2.0 4.0 90 NA 
Artichoke 1.0 1.0 NA 200 
Avocado 2.0 6.0 90 28 
Berry and Small Fruit: 
Bushberry, Crop 
Subgroup 13-07B 
Blueberry, Highbush 
1.8 3.6 90 0 
Berry and Small Fruit: 
Caneberry, Crop 
Subgroup 13-07A 
Blackberry 
Raspberry 
1.8 Soil: 3.6 
Foliar: 0.2 
90 45 
Berry and Small Fruit: 
Cranberry 
0.875 2.625 90 45 
Berry and Small Fruit: 
Small fruit vine 
climbing (except 
grape), Crop Subgroup 
13-07E 
Kiwifruit, fuzzy 
Gooseberry 
0.35 1.75 30 7 
Berry and Small Fruit: 
Strawberry 
Strawberry, field nursery 
0.5 1.5 
 
except for field 
nursery: 1.0 
 
30 0 
Brassica Head and 
Stem Vegetables, Crop 
Group 5-16 
Broccoli 
Soil: 1.0 
Foliar: 0.125 
Soil: 1.0 
Foliar: 0.50 
Soil: NA 
Foliar: 14 
7

69 
Crop or Crop 
Group/Subgroup with 
examples 
Maximum Single 
Application Rate 
(lb ai/A) 
Maximum 
Annual 
Application Rate 
(lb ai/A/year) 
Minimum 
Application 
Interval 
(days) 
Pre-Harvest 
Interval (PHI, 
days) 
Cauliflower 
Brassica Leafy 
Greens, Crop 
Subgroup 4-16B 
Mustard Greens 
Soil:1.0 
 Foliar: 0.125 
Soil: 1.0 
 Foliar: 0.50 
Soil: NA 
Foliar: 14 
7 
Bulb Vegetables, Crop 
Group 3-07 
Onion, bulb 
Onion, green 
0.5 
 
For onions 
(bulb): 
Soil: 1.0 
Foliar: 0.5 
 
 
For onions 
(green): 
Soil: 1.0 
Foliar: 0.3 
NA NA 
Cacao 0.01 0.04 21 30 
Citrus Fruit, Crop 
Group 10 
Sweet Orange, 
Lemon 
3.0 
 
 
6.0 
 
 
90 0 
Clover 0.25 0.25 NA 90 
Cotton, Crop 
Subgroup 20C 
0.063 for 38-inch 
row centers (0.15 
fl oz/1000 row ft) 
0.125 NA NA 
Cucurbit Vegetables, 
Crop Group 9 
Cucumber, 
Muskmelon, and 
Summer Squash 
1.0 Soil: 1.0 
Foliar: 0.5 
20 
 unless following 
transplant water 
application: 14 
5 
Fruiting Vegetables, 
Crop Group 8-10 
 
Pepper, 
Tomato 
0.5 
 
except for 
Tomato: 1.0 
Soil: 1.5 
Foliar: 0.5 
30 
unless following 
transplant water 
application: 14 
 
except for Tomato: 
28 
7 
Grapes 1.8 Soil: 5.4 
Foliar: 0.4 
90 
 
60 
Grass Forage, Fodder, 
and Hay, Crop Group 
17 
Bluegrass, 
Fescue 
0.5 0.5 NA 60 
Herbs (fresh and 
dried), Crop Subgroup 
19A 
Basil, 
Chive 
1.0 2.0 28 21 
Hops 0.25 Soil: 0.25 
Foliar: 0.5 
Soil: NA 
Foliar: 14 
45 
Leafy Vegetables: 
Leafy Greens, Crop 
Subgroup 4-16A 
Head Lettuce 
1.0 Soil: 1.0 
 
except for 
Lettuce: 
Soil: NA 
Foliar (lettuce 
only): 14 
7

70 
Crop or Crop 
Group/Subgroup with 
examples 
Maximum Single 
Application Rate 
(lb ai/A) 
Maximum 
Annual 
Application Rate 
(lb ai/A/year) 
Minimum 
Application 
Interval 
(days) 
Pre-Harvest 
Interval (PHI, 
days) 
Leaf Lettuce 
 
Soil: 1.0 
Foliar: 0.4 
 
 
 
Spinach 1.0 Soil: 1.0 at 
planting followed 
by either: 
 
Shanked: 0.25 
 
or 
 
 Foliar: 0.4 
21 3 only if soil 
application does 
not exceed 1.0 
lb ai/A/year and 
foliar application 
does not exceed 
0.25 lb 
ai//A/year 
 
otherwise: 21 
 
Legume Vegetables, 
Crop Group 6-22 
0.5 0.5 NA NA 
Succulent Shelled 
Beans, Crop Subgroup 
6-22C 
 
Soil: 0.5 
Foliar: 0.1 
Soil: 0.5 
Foliar: 0.4 
14 3 
Succulent Shelled 
Peas, Crop Subgroup 
6-22D 
 
Soil: 0.5 
Foliar: 0.1 
Soil: 0.5 
Foliar: 0.4 
14 3 
Peanut Soil: 0.125 
Foliar: 0.5 
Soil: 0.125 
Foliar: 0.50 
NA NA 
Pineapple, Crown Dip 0.50 0.50 NA NA 
Root and Tuber 
Vegetables: 
Carrot 
0.65 Total: 1.4 
 
or 
 
Soil: 0.65 
Foliar: 0.75 
 
14 7 
Root and Tuber 
Vegetables: 
Ginseng 
 
0.375 Soil: 0.375 
Foliar: 1.125 
 
NA NA 
Root and Tuber 
Vegetables: 
Potato 
Soil: 0.19 (based 
on a 36-inch row 
spacing) 
Foliar: 0.1 
Soil: 0.34 
Foliar: 0.40 
14 14 
Root and Tuber 
Vegetables, Crop 
Group 1 (except 
Carrot, Ginseng, and 
Potato) 
Sugar Beet, 
Radish 
 
1.0 1.0 NA NA 
Soybean 0.625 0.625 NA NA 
Celtuce 1.0 1.0 NA 7

71 
Fennel 1.0 1.0 NA 7 
Kohlrabi Soil: 1.0 
Foliar: 0.125 
Soil: 1.0 
Foliar: 0.5 
Soil: NA 
Foliar: 14 
7 
Leaf Petiole 
Vegetables, Crop 
Subgroup 22B 
Celery, 
Rhubarb, 
Udo 
1.0 1.0 NA NA 
Stalk and Stem 
Vegetables, Crop 
Subgroup 22A 
Asparagus, 
Aloe Vera 
0.5 
 
1.0 
 
30 
 
 
1 
 
Stone Fruits, Crop 
Group 12 
Sweet Cherry 
Peach 
Plum 
2.0 6.0 60 0 
Tobacco 1.5 1.5 14 NA 
Tree Nuts, Crop Group 
14-12 
Almond 
Pecan 
2.0 6.0 60 30 
Tropical and 
Subtropical Fruit: 
Medium to Large Fruit, 
Smooth Peel 
Mango 
Papaya 
1.5 3.0 90 1 
Tropical and 
Subtropical Fruit: 
Medium to Large Fruit, 
Rough or Hairy Peel 
Atemoya 
Sugar apple 
1.5 3.0 90 30 
Wasabi 0.75 4.5 7 7 
 
[ End of Optional Text]

72 
 
Ridomil Gold®, the ALLIANCE FRAME, the Syngenta Logo, and the PURPOSE ICON are 
trademarks of a Syngenta Group Company 
 
Viton™ is a trademark of The Chemours Company FC, LLC 
 
©20XX Syngenta 
 
For non-emergency (e.g., current product information), call 
Syngenta Crop Protection at 1-800-334-9481. 
 
 
Manufactured for: 
Syngenta Crop Protection, LLC 
P.O. Box 18300 
Greensboro, North Carolina 27419-8300 
 
Mefenoxam 2E 1145 MAS 0507 AMEND-B 1021-CL - JVB - 05/11/2023 
000100-01145.20211015B.MEFENOXAM-2E.AMEND.OCT2021-CL.pdf