crop-chem-docs/corpus/epa_ppls/100-1256.md

# AXIAL XL

- EPA Reg No: **100-1256**
- Registrant: SYNGENTA CROP PROTECTION, LLC
- Signal word: Warning
- Active ingredients: Pinoxaden (5.05%)
- Label accepted: 2022-05-03
- Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000100-01256-20220503.pdf

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UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 
 WASHINGTON, DC 20460 
 
 
 
OFFICE OF CHEMICAL SAFETY 
AND POLLUTION PREVENTION 
 
May 3, 2022 
 
Jordan Moseley 
Regulatory Product Manager 
Syngenta Crop Protection, LLC 
P. O. Box 18300 
Greensboro, NC 27419 
 
Subject: Registration Review Label Mitigation for Pinoxaden 
 Product Name: AXIAL XL 
EPA Registration Number: 100-1256 
 Application Date: December 15, 2020 
Decision Number: 568875 
 
Dear Jordan Moseley: 
 
The Agency, in accordance with the Federal Insecticide, Fungicide and Rodenticide Act 
(FIFRA), as amended, has completed reviewing all the information submitted with your 
application to support the Registration Review of the above referenced product in connection 
with the Pinoxaden Interim Decision, and has concluded that your submission is acceptable. The 
label referred to above, submitted in connection with registration under FIFRA, as amended, is 
acceptable. 
 
Should you wish to add/retain a reference to the company’s website on your label, then please be 
aware that the website becomes labeling under the Federal Insecticide Fungicide and Rodenticide 
Act and is subject to review by the Agency. If the website is false or misleading, the product 
would be misbranded and unlawful to sell or distribute under FIFRA section 12(a)(1)(E). 40 
CFR 156.10(a)(5) list examples of statements EPA may consider false or misleading. In addition, 
regardless of whether a website is referenced on your product’s label, claims made on the 
website may not substantially differ from those claims approved through the registration process. 
Therefore, should the Agency find or if it is brought to our attention that a website contains false 
or misleading statements or claims substantially differing from the EPA approved registration, 
the website will be referred to the EPA’s Office of Enforcement and Compliance. 
 
A stamped copy of your labeling is enclosed for your records. This labeling supersedes 
all previously accepted labeling. You must submit one copy of the final printed labeling 
before you release the product for shipment with the new labeling. In accordance with 40 
CFR 152.130(c), you may distribute or sell this product under the previously approved 
labeling for 12 months from the date of this letter. After 12 months, you may only 
distribute or sell this product if it bears this new revised labeling or subsequently 
approved labeling. “To distribute or sell” is defined under FIFRA section 2(gg) and its 
implementing regulation at 40 CFR 152.3.

Page 2 of 2 
EPA Reg. No. 100-1256 
Decision No. 568875 
 
 
If you have any questions about this letter, please contact Julie Javier by phone at 202-566-2285, 
or via email at javier.julie@epa.gov. 
 
 
 Sincerely, 
 
 
 Linda Arrington, Branch Chief 
 Risk Management and Implementation Branch 4 
 Pesticide Re-Evaluation Division 
 Office of Pesticide Programs 
 
 
Enclosure

[Master Label]
PINOXADEN GROUP 1 HERBICIDE
Axial® XL Herbicide
Postemergence herbicide for control of grass weeds in wheat and barley
Active Ingredient:
Pinoxaden*.............................................................................................................. 5.05%
Other Ingredients: 94.95%
Total: 100.00%
*CAS No. 243973-20-8
Contains petroleum distillates.
Axial XL Herbicide contains 0.42 lb. of pinoxaden active ingredient per gallon.
KEEP OUT OF REACH OF CHILDREN.
WARNING/AVISO
Si usted no entiende la etiqueta, busque a alguien para que se la explique a usted en
detalle. (If you DO NOT understand the label, find someone to explain it to you in 
detail.)
See additional precautionary statements and directions for use inside booklet.
EPA Reg. No. 100-1256
EPA Est. 
___________
Net Contents
May 03, 2022
100-1256

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FIRST AID
If on skin or 
clothing
x Take off contaminated clothing.
x Rinse skin immediately with plenty of water for 15-20 minutes.
x Call a poison control center or doctor for treatment advice.
If in eyes x Hold eye open and rinse slowly and gently with water for 15-20
minutes.
x Remove contact lenses, if present after the first 5 minutes, then 
continue rinsing eye.
x Call a poison control center or doctor for treatment advice.
If swallowed x Immediately call a poison control center or doctor.
x DO NOT induce vomiting unless told to do so by a poison control 
center or doctor.
x DO NOT give any liquid to the person.
x DO NOT give anything by mouth to an unconscious person.
If inhaled x Move person to fresh air.
x If person is not breathing, call 911 or an ambulance, then give 
artificial respiration, preferably by mouth-to-mouth, if possible.
x Call a poison control center or doctor for further treatment 
advice.
Have the product container or label with you when calling a poison control center or 
doctor or going for treatment.
Note to Physician
Contains petroleum distillates – vomiting may cause aspiration pneumonia.
HOT LINE NUMBER
For 24 Hour Medical Emergency Assistance (Human or Animal) or
Chemical Emergency Assistance (Spill, Leak, Fire, or Accident)
Call
1-800-888-8372
PRECAUTIONARY STATEMENTS
Hazards to Humans and Domestic Animals
WARNING/AVISO
Causes skin irritation. DO NOT get on skin or clothing. Causes moderate eye irritation. 
Avoid contact with eyes. Harmful if swallowed or inhaled. Wash thoroughly with soap 
and water after handling and before eating, drinking, chewing gum, or using tobacco. 
Remove and wash contaminated clothing before reuse.

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Personal Protective Equipment (PPE)
Some materials that are chemical resistant to this product are listed below. 
Applicators and other handlers must wear:
x Coveralls worn over short-sleeved shirt and long pants
x Socks and chemical-resistant footwear
x Chemical-resistant gloves, such as barrier laminate, butyl rubber t14 mils, nitrile 
rubber t14 mils, neoprene rubber t14 mils, polyvinyl chloride (PVC) t14 mils, or 
Viton® t14 mils
Follow manufacturer’s instructions for cleaning/maintaining PPE. If no such instructions 
for washables exist, use detergent and hot water. Keep and wash PPE separately from 
other laundry.
When mixing or loading wear a chemical resistant apron. For overhead exposure wear 
chemical-resistant headgear. When cleaning equipment wear a chemical-resistant 
apron.
Engineering Control Statements
When handlers use closed systems, enclosed cabs, or aircraft in a manner that meets the 
requirements listed in the Worker Protection Standard (WPS) for agricultural pesticides 
[40 CFR 170.240(d)(4-6)], the handler PPE requirements may be reduced or modified as 
specified in the WPS.
User Safety Recommendations
Users should:
x Wash hands before eating, drinking, chewing gum, using tobacco, or using the toilet.
x Remove clothing/PPE immediately if pesticide gets inside. Then wash thoroughly and 
put on clean clothing.
x Remove PPE immediately after handling this product. Wash the outside of gloves 
before removing. As soon as possible, wash thoroughly and change into clean 
clothin
g.
Environmental Hazards
This product is toxic to oysters. For terrestrial uses: DO NOT apply directly to water, to 
areas where surface water is present, or to intertidal areas below the mean high water 
mark. DO NOT contaminate water when disposing of equipment wash water or rinsate.
NON-TARGET ORGANISM ADVISORY STATEMENT: This product is toxic to plants 
and may adversely impact the forage and habitat of non-target organisms, including 
pollinators, in areas adjacent to the treated site. Protect the forage and habitat of non-
target organisms by following label directions intended to minimize spray drift.

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Physical or Chemical Hazards
DO NOT use or store near heat or open flame.
CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY
NOTICE: Read the entire Directions for Use and Conditions of Sale and Limitation of 
Warranty and Liability before using this product. If the terms are not acceptable, return 
the product at once, unopened, and the purchase price will be refunded.
The Directions for Use of this product must be followed carefully. It is impossible to 
eliminate all risks inherently associated with the use of this product. Crop injury, 
ineffectiveness or other unintended consequences may result because of such factors
as manner of use or application, weather or crop conditions, presence of other materials 
or other influencing factors in the use of the product, which are beyond the control of 
SYNGENTA CROP PROTECTION, LLC or Seller. To the extent permitted by 
applicable law, Buyer and User agree to hold SYNGENTA and Seller harmless for any 
claims relating to such factors.
SYNGENTA warrants that this product conforms to the chemical description on the label 
and is reasonably fit for the purposes stated in the Directions for Use, subject to the 
inherent risks referred to above, when used in accordance with directions under normal 
use conditions. To the extent permitted by applicable law: (1) this warranty does not 
extend to the use of the product contrary to label instructions or under conditions not 
reasonably foreseeable to or beyond the control of Seller or SYNGENTA, and, (2) Buyer 
and User assume the risk of any such use. TO THE EXTENT PERMITTED BY 
APPLICABLE LAW, SYNGENTA MAKES NO WARRANTIES OF MERCHANTABILITY 
OR OF FITNESS FOR A PARTICULAR PURPOSE NOR ANY OTHER EXPRESS OR 
IMPLIED WARRANTY EXCEPT AS WARRANTED BY THIS LABEL.
To the extent permitted by applicable law, in no event shall SYNGENTA be liable for 
any incidental, consequential or special damages resulting from the use or handling of 
this product. TO THE EXTENT PERMITTED BY APPLICABLE LAW, THE 
EXCLUSIVE REMEDY OF THE USER OR BUYER, AND THE EXCLUSIVE LIABILITY 
OF SYNGENTA AND SELLER FOR ANY AND ALL CLAIMS, LOSSES, INJURIES 
OR DAMAGES (INCLUDING CLAIMS BASED ON BREACH OF WARRANTY, 
CONTRACT, NEGLIGENCE, TORT, STRICT LIABILITY OR OTHERWISE) 
RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, SHALL BE THE 
RETURN OF THE PURCHASE PRICE OF THE PRODUCT OR, AT THE ELECTION 
OF SYNGENTA OR SELLER, THE REPLACEMENT OF THE PRODUCT.
SYNGENTA and Seller offer this product, and Buyer and User accept it, subject to the 
foregoing Conditions of Sale and Limitation of Warranty and Liability, which may not be 
modified except by written agreement signed by a duly authorized representative of 
SYNGENTA.

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DIRECTIONS FOR USE
It is a violation of Federal law to use this product in a manner inconsistent with its labeling.
Axial XL Herbicide may be used only in accordance with directions on this label or in 
separately published Syngenta supplemental labeling directions for this product.
DO NOT apply this product in a way that will contact workers or other persons, either 
directly or through drift. Only protected handlers may be in the area during application. 
For any requirements specific to your State or Tribe, consult the agency responsible for 
pesticide regulation.
AGRICULTURAL USE REQUIREMENTS
Use this product only in accordance with its labeling and with the Worker Protection 
Standard, 40 CFR part 170. This Standard contains requirements for the protection of 
agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of 
agricultural pesticides. It contains requirements for training, decontamination, 
notification, and emergency assistance. It also contains specific instructions and 
exceptions pertaining to the statements on this label about personal protective 
equipment (PPE) and restricted-entry interval. The requirements in this box only apply 
to uses of this product that are covered by the Worker Protection Standard.
DO NOT enter or allow worker entry into treated areas during the restricted-entry 
interval (REI) of 48 hours.
PPE required for early entry to treated areas that is permitted under the Worker 
Protection Standard and that involves contact with anything that has been treated, such 
as plants, soil, or water is:
x Coveralls worn over short-sleeved shirt and long pants
x Socks and chemical-resistant footwear
x Chemical-resistant gloves, such as barrier laminate, butyl rubber t14 mils, nitrile 
rubber t14 mils, neoprene rubber t14 mils, polyvinyl chloride (PVC) t14 mils, or 
Viton t14 mils
FAILURE TO FOLLOW THE DIRECTIONS FOR USE AND PRECAUTIONS ON THIS 
LABEL MAY RESULT IN CROP INJURY AND/OR POOR WEED CONTROL.
PRODUCT INFORMATION
Axial XL Herbicide is a systemic, postemergence herbicide for the control of several grass 
weed species in all varieties of spring wheat (excluding durum), winter wheat, and barley.

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Axial XL Herbicide is rapidly absorbed by weed foliage and translocated to the growing 
points of leaves and stems where it inhibits the acetyl CoA carboxylase (ACCase) 
enzyme. Susceptible weed species generally stop growing within 48 hours of treatment, 
turn yellow within one to three weeks, and are completely controlled within three to five 
weeks. Level and rate of control depend on weed species, growing conditions, crop 
competition, and coverage. Thorough spray coverage of target weeds is essential for 
consistent control.
Although Axial XL Herbicide does not control broadleaf weeds, it can be tank mixed with 
a wide range of broadleaf herbicides to provide broad-spectrum one-pass weed control. 
It can also be tank mixed with Tilt® Fungicide, Quilt® Fungicide, Warrior II with Zeon 
Technology®, and Karate® with Zeon Technology™. See the section entitled Tank 
Mixes of Axial XL Herbicide with Broadleaf Weed Herbicides, Fungicides, 
Insecticides and Liquid Nitrogen Fertilizers. Herbicides not listed on this label for tank 
mixing with Axial XL Herbicide may be applied sequentially. For optimum results, apply 
Axial XL Herbicide first and allow at least 4 days after application of Axial XL Herbicide 
before applying these herbicides sequentially.
Weeds Controlled
Axial XL Herbicide controls green foxtail, yellow foxtail, giant foxtail, wild oat, volunteer 
oat, Persian darnel, Italian (annual) ryegrass, barnyardgrass, canarygrass, wild proso 
millet, and windgrass.
Use Rates
Apply the specified rate of Axial XL Herbicide using ground or aerial equipment, in a 
minimum of 5 gal. of water per acre (see Ground and Aerial Application Procedures
section for additional information).
WEEDS CONTROLLED
A USE RATE
Wild oat, Avena fatua
Volunteer oat, Avena sativa
Green foxtail, Setaria viridis
Yellow foxtail, Setaria glauca
Giant foxtail, Setaria faberi
Italian (annual) ryegrass, Lolium 
multiflorum
Persian darnel, Lolium persicum
Barnyardgrass, Echinochloa crus-galli
Canarygrass, Phalaris spp.
Wild proso millet, Panicum miliaceum
Wind
grass, Apera spp.
Axial XL Herbicide 16.4 fl. oz./A
AWhen tank mixing broadleaf herbicides, refer to Tank Mixes of Axial XL Herbicide 
with Broadleaf Weed Herbicides, Fungicides, Insecticides and Liquid Nitrogen 
Fertilizers section for exceptions and additional information on weeds controlled.

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Resistance Management 
PINOXADEN GROUP 1 HERBICIDE
For resistance management, Axial Herbicide is a Group 1 herbicide (ACCase-inhibitor 
mode of action). Some naturally occurring grass weed populations have been identified 
as resistant to herbicides with the ACCase-inhibitor mode of action. Any weed 
population may contain or develop plants naturally resistant to Axial Herbicide and other 
Group 1 herbicides. Selection of resistant biotypes, through repeated use of these 
herbicides in the same field or lower than labeled use rates, may result in weed control 
failures. The resistant biotypes may dominate the weed population if these herbicides 
are used repeatedly in the same field. Appropriate resistance management strategies 
should be followed. If resistance is suspected, contact your local Syngenta 
representative and/or agricultural advisor for assistance.
Principles of Herbicide Resistant Weed Management
Scout and know your field
x Know weed species present in the field to be treated through scouting and field 
history. An understanding of weed biology is useful in designing a resistance 
management strategy. Ensure the weed management program will control all 
weeds present.
x Fields should be scouted prior to application to determine species present and 
growth stage. Always apply this herbicide at the full labeled rate and correct 
timing for the weeds present in the field. 
Utilize non-herbicidal practices to add diversity
x Use diversified management tactics including cover crops, mechanical weed 
control, harvest weed seed control, and crop rotation as appropriate.
Use good agronomic practices, start clean and stay clean
x Use good agronomic practices that enhance crop competitiveness.
x Plant into weed-free fields utilizing tillage or an effective burndown herbicide for 
control of emerged weeds.
x Sanitize farm equipment to avoid spreading seed or vegetative propagules prior 
to leaving fields.
Difficult to control weeds
x Fields with difficult to control weeds should be planted in rotation with crops that 
allow the use of herbicides with an alternative mode of action or different 
management practices.
x Difficult to control weeds may require sequential applications, for example a 
broad spectrum preemergence herbicide followed by one or more

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postemergence herbicide applications. Utilize herbicides containing different 
modes of action effective on the target weeds in sequential applications. 
DO NOT overuse the technology
x DO NOT use more than two applications of this or any other herbicide with the 
same mode of action in a single growing season unless mixed with an herbicide 
with a different mode of action which provides overlapping spectrum for the 
difficult to control weeds.
Scout and inspect fields following application
x Prevent an influx of weeds into the field by controlling weeds in field borders.
x Scout fields after application to verify that the treatment was effective.
x Suspected- herbicide resistant weeds may be identified by these indicators
• Failure to control a weed species normally controlled by the herbicide at 
the dose applied, especially if control is achieved on adjacent weeds;
• A spreading patch of non-controlled plants of a particular weed species; 
and
• Surviving plants mixed with controlled individuals of the same species.
x Report non-performance of this product to your Syngenta retailer, Syngenta 
representative, or call 1-866-Syngent(a) (866-796-4368). If resistance is 
suspected ensure weed escapes are controlled using an herbicide with an 
effective mode of action and/or use non-chemical means to prevent further seed 
production.
Prevent weed escapes before, during, and after harvest
x DO NOT allow weed escapes to produce seed or vegetative structures for 
example tubers or stolons which contribute to spread and survival. Consider 
harvest weed seed management and control weeds post-harvest to prevent seed 
production. 
Resistant weeds
Contact your local Syngenta representative, retailer, crop advisor or extension agent to 
determine if weeds resistant to the mode of action contained in this product are present 
in your area. Premixes are intended to broaden the spectrum of weeds that are 
controlled. Some weeds may be controlled by only one of the active ingredients in this 
product. If resistant biotypes have been reported, use the full labeled rate of this 
product, apply at the labeled timing, and tank-mix with an additional different mode of 
action product so there are multiple effective modes of application for each suspected 
resistant weed.
Rotational Crop Restrictions
The following crops may be planted at the specified interval following application of 
Axial XL Herbicide.

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Crop Rotational Interval
Wheat (including Durum) and Barley 0 days
Leafy and Root Crops 30 da ys
Other Cereal Grains and All Other Crops 90 da ys
APPLICATION PROCEDURES
Timing of Application
Apply Axial XL Herbicide to all varieties of spring wheat (excluding durum), winter wheat, 
and barley from the 2-leaf stage to pre-boot stage. Refer to the Crop Use Directions
section for grazing and harvest restrictions.
Precaution: DO NOT apply to a crop that is stressed by conditions such as frost, low 
fertility, drought, flooding, disease damage, or insect damage, as crop injury may result.
When tank mixing with a broadleaf herbicide, insecticide or fungicide, always refer to the 
label of the tank-mix partner prior to use.
For optimum results, apply Axial XL Herbicide to actively growing weeds. An early 
application will maximize crop yields by reducing weed competition. Weed control 
following application of Axial XL Herbicide alone or in combination with broadleaf 
herbicides can be reduced or delayed under conditions of stress, such as drought, heat, 
insufficient fertility, flooding, and prolonged cool temperatures. Grass escapes or 
re-tillering may occur if application is made during prolonged conditions of stress. 
Optimum weed control will be obtained if application of Axial XL Herbicide is delayed until 
the conditions of stress have ended and weeds are once again actively growing. Weeds 
emerging after Axial XL Herbicide application will not be controlled.
TIMING OF APPLICATION TO WEEDS
Weed Leaves on Main Stem Tillers
Persian Darnel
Volunteer Oat
Wild Oat
1 to 6-leaf stage on main 
stem
Prior to emergence of the 
4
th tiller.
Giant Foxtail
Green Foxtail
Yellow Foxtail
Italian (Annual) Ryegrass
Barnyardgrass
Canarygrass
Wild Proso Millet
Wind
grass
1 to 5-leaf stage on main 
stem
For optimum control, apply 
prior to emergence of the 
3
rd tiller and while weeds 
are actively growing.

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Rainfastness
Axial XL Herbicide applied alone is not affected by rain falling 30 minutes or more after 
application.
MANDATORY SPRAY DRIFT MANAGEMENT
Aerial Applications:
x Do not release spray at a height greater than 10 ft above the ground or 
vegetative canopy, unless a greater application height is necessary for pilot 
safet
y.
x Applicators are required to use a medium or coarser droplet size (ASABE S572).
x If the windspeed is 10 miles per hour or less, applicators must use ½ swath 
displacement upwind at the downwind edge of the field. When the windspeed is 
between 11-15 miles per hour, applicators must use ¾ swath displacement 
upwind at the downwind ed
ge of the field.
x Do not apply when wind speeds exceed 15 mph at the application site. If the 
windspeed is greater than 10 mph, the boom length must be 65% or less of the 
wingspan for fixed wing aircraft and 75% or less of the rotor diameter for 
helicopters. Otherwise, the boom length must be 75% or less of the wingspan for 
fixed-win
g aircraft and 90% or less of the rotor diameter for helicopters.
x Do not apply during ground level temperature inversions.
Ground Boom Applications:
x User must only apply with the release height recommended by the manufacturer, 
but no more than 4 feet above the ground or crop canopy.
x Applicators are required to use a medium or coarser droplet size (ASABE S572).
x Do not apply when wind speeds exceed 15 miles per hour at the application site.
x Do not apply during temperature inversions.
SPRAY DRIFT ADVISORIES
THE APPLICATOR IS RESPONSIBLE FOR AVOIDING OFF-SITE SPRAY DRIFT. BE 
AWARE OF NEARBY NON-TARGET SITES AND ENVIRONMENTAL CONDITIONS.
IMPORTANCE OF DROPLET SIZE
An effective way to reduce spray drift is to apply large droplets. Use the largest droplets 
that provide target pest control. While applying larger droplets will reduce spray drift, the 
potential for drift will be greater if applications are made improperly or under unfavorable 
environmental conditions.
Controlling Droplet Size – Ground Boom
x Volume - Increasing the spray volume so that larger droplets are produced will 
reduce spray drift. Use the highest practical spray volume for the application. If a 
greater spray volume is needed, consider using a nozzle with a higher flow rate.

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x Pressure - Use the lowest spray pressure recommended for the nozzle to 
produce the target spray volume and droplet size.
x Spray Nozzle - Use a spray nozzle that is designed for the intended application. 
Consider using nozzles designed to reduce drift.
Controlling Droplet Size – Aircraft
x Adjust Nozzles - Follow nozzle manufacturers’ recommendations for setting up 
nozzles. Generally, to reduce fine droplets, nozzles should be oriented parallel 
with the airflow in flight.
BOOM HEIGHT – Ground Boom
For ground equipment, the boom should remain level with the crop and have minimal 
bounce.
RELEASE HEIGHT - Aircraft
Higher release heights increase the potential for spray drift.
SHIELDED SPRAYERS
Shielding the boom or individual nozzles can reduce spray drift. Consider using shielded 
sprayers. Verify that the shields are not interfering with the uniform deposition of the 
spray on the target area.
TEMPERATURE AND HUMIDITY
When making applications in hot and dry conditions, use larger droplets to reduce 
effects of evaporation.
TEMPERATURE INVERSIONS 
Drift potential is high during a temperature inversion. Temperature inversions are 
characterized by increasing temperature with altitude and are common on nights with 
limited cloud cover and light to no wind. The presence of an inversion can be indicated 
by ground fog or by the movement of smoke from a ground source or an aircraft smoke 
generator. Smoke that layers and moves laterally in a concentrated cloud (under low 
wind conditions) indicates an inversion, while smoke that moves upward and rapidly 
dissipates indicates good vertical air mixing. Avoid applications during temperature 
inversions. 
WIND 
Drift potential generally increases with wind speed. AVOID APPLICATIONS DURING 
GUSTY WIND CONDITIONS. 
Applicators need to be familiar with local wind patterns and terrain that could affect 
spray drift.

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Sensitive Areas
This pesticide may only be applied when the potential for drift to adjacent sensitive areas, 
e.g., residential areas, bodies of water, non-target plants is minimal, (i.e., when the wind 
is blowing away from the sensitive area.)
Avoid all direct or indirect contact (such as spray drift) of Axial XL Herbicide with crops 
other than those specified for treatment on this label, since injury may occur.
Chemigation 
DO NOT apply this product through any type of irrigation system.
MIXING PROCEDURES
Mixing Instructions
1. Clean spray tank and half fill with clean wate r. Start agitation or bypass system.
2. If a broadleaf herbicide is to be used, add the product FIRST, prior to adding Axial 
XL Herbicide and agitate for 2-3 minutes.
3. Add correct amount of Axial XL Herbicide and agitate for 2-3 minutes.
4. Add remainder of water and then maintain constant agitation.
5. After any break in spraying operations, agitate thoroughly before spraying again.
6. Use the spray solution as soon as it is prepared.
Sprayer Cleanup
Prior to using Axial XL Herbicide, ensure that the spray tank, lines and screens and 
filters are thoroughly clean.
Thoroughly clean application equipment immediately after spraying Axial XL Herbicide. 
Ensure that all traces of the product are removed. The following directions are 
provided:
1. Drain and flush tank walls, boom, and all hoses for 10 minutes with clean water. 
DO NOT clean the sprayer near desirable vegetation, wells, or other water 
sources. 
2. Remove the nozzles and screens and wash separately. 
3. Dispose of all rinsates in accordance with state and local regulations.
4. If a broadleaf herbicide, insecticide, or fungicide tank-mix partner is used, always 
check tank-mix partner label for any additional cleanup procedures.

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CROP USE DIRECTIONS
Wheat and Barley
Axial XL Herbicide can be used on all varieties of spring wheat (excluding durum), winter 
wheat, and barley. DO NOT allow spray to drift to adjacent fields seeded to crops other 
than wheat or barley. DO NOT treat wheat or barley underseeded to forages.
x Make one application per crop season, not to exceed 16.4 fl. oz. of Axial XL Herbicide 
per acre per 12 consecutive months.
x DO NOT graze livestock or harvest forage for hay from treated wheat and barley for a 
minimum of 30 days following application.
x DO NOT harvest grain for 60 days following application.
x Wheat and barley straw may be fed to livestock 60 days after application.
Tank Mixes of Axial XL Herbicide with Broadleaf Weed Herbicides, Fungicides, 
Insecticides and Liquid Nitrogen Fertilizers 
For broad-spectrum control of annual grass and broadleaf weeds, tank mix Axial XL 
Herbicide with one of the broadleaf herbicides or broadleaf herbicide combinations listed 
in the following table. Consult the label of the tank-mix partner for a list of broadleaf 
weeds controlled, rates, application timing, recropping restrictions, grazing interval 
restrictions, directions for use, and precautions. Use in accordance with the most 
restrictive of label limitations and precautions. DO NOT exceed label dosage rates. This 
product cannot be mixed with any other product whose label prohibits such a mixture.

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Table 1: For control of wild oat, volunteer oat, green foxtail, yellow foxtail, Italian 
(annual) ryegrass, and broadleaf weeds (refer to the broadleaf tank-mix partner label for 
weeds controlled), use Axial XL Herbicide at 16.4 fl. oz./A plus one of the following
single or two-way broadleaf herbicide combinations. Broadleaf herbicide combinations 
other than those listed in the table below are not recommended.
SELECT ONLY ONE BROADLEAF HERBICIDE TANK-MIX COMBINATION LISTED 
IN THE TABLE BELOW
Weeds Controlled by Axial XL Herbicide
at 16.4 fl. oz./A*
Broadleaf HerbicideA Rate
Wild 
Oat
Volunteer 
Oat
Green
Foxtail
Yellow
Foxtail
Italian
Ryegrass
Affinity™ BroadSpecB 0.4-0.6 oz./A C C S C C
Affinity™ TankMixB +
Bronate® Advanced
0.6 oz./A + 0.6-0.8 
pt./A C C -- S C
Affinity TankMixB +
MCPA EsterF
0.6 oz./A + 0.5-0.75 
pt./A C C C C C
Affinity TankMixB +
Starane®
0.6 oz./A +
0.5-0.67 pt./A CCS SC
Affinity TankMixB +
WideMatch™
0.6 oz./A + 1 pt./A CCC CC
Ally® XPB 0.1 oz./A C C -- -- C
Amber®B 0.28-0.47 oz./A C C -- -- C
Bronate AdvancedC 0.6-1.2 pt./A C C C C C
Buctril®D 0.75-1.5 pt./A C C C C C
BuctrilD + MCPA 
EsterF
0.75-1.5 pt./A + 0.5-
0.75 pt./A C C C C C
Curtail™ M 1.75 pt./A C C C -- --
Express® XPB 0.25-0.33 oz./A C C S S C
Express XPB + MCPA 
esterF
0.25-0.33 oz./A + 
0.5-0.75 pt./A CCS SC
Finesse®B 0.2-0.4 oz./A C C -- -- C
Harmony® Extra XPB 0.3-0.6 oz./A C C C C C
Harmony Extra XPB +
MCPA EsterF
0.3-0.5 oz./A +
0.5-0.75 pt./A C C C C C
Harmony® SGB 0.45-0.9 oz./A C C C C C
Harmony SGB,E +
Bronate AdvancedE
0.45-0.75 oz./A + 0.6-
1 pt./A C C -- -- C
Harmony SGB +
Buctril
0.45-0.75 oz./A + 
0.75-1.5 pt./A C C -- -- C
Harmony SGB +
MCPA EsterF
0.45-0.75 oz./A + 0.5-
0.75 pt./A C C C C C
Huskie™B 11-13 fl. oz./A C C C C C
Hat Trick® Threeway 1.5 pt/A C C C C C
MCPA EsterF 0.5-0.75 pt./A C C C C C
Orion™B 17 oz./A C C C C C
OrionB + Buctril 17 oz./A + 1 pt./A C C S C C
OrionB + Starane 17 oz./A + 0.5-0.67 
pt./A CCC CC
OrionB + Stinger® 17 oz./A + 0.33 pt./A C C C C C
Peak®B 0.25-0.5 oz./A C C C C C

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Weeds Controlled by Axial XL Herbicide
at 16.4 fl. oz./A*
Broadleaf HerbicideA Rate
Wild 
Oat
Volunteer 
Oat
Green
Foxtail
Yellow
Foxtail
Italian
Ryegrass
PeakB + Bronate 
Advanced
0.25-0.5 oz./A +
0.6-0.8 pt./A CCS CC
PeakB + MCPA esterF 0.25-0.5 oz./A +
0.5-0.75 pt./A CCC CC
PeakB + Starane 0.25-0.5 oz./A + 0.5-
0.67 pt./A CC -- C
Pulsar™ 8.3-12.5 fl. oz./A C C C C C
Pulsar + Affinity 
TankMixB
8.3-12.5 fl. oz./A + 
0.6 oz./A
CCC CC
Pulsar + AmberB 8.3-12.5 fl. oz./A + 
0.28 oz./A
CCC CC
Pulsar + MCPA 
esterF
8.3-12.5 fl. oz./A + 
8.6 fl. oz./A
CCC CC
Pulsar + PeakB 8.3-12.5 fl. oz./A + 
0.25 oz/A
CCC CC
Starane 0.5-0.67 pt./A C C C C C
Starane + Bronate 
AdvancedC
0.5-0.67 pt./A + 0.6-1
pt./A C C C C C
Starane + Harmony 
Extra XP
B
0.5-0.67 pt./A + 0.3-
0.4 oz./A C C C -- C
Starane + Harmony 
SG
B
0.5-0.67 pt./A + 0.45-
0.75 oz./A CCC CC
Starane® + Sword®G 1.125 pt./A C C C C C
Starane NXT 14 fl. oz./A C C C C C
WideMatch™ 1 pt./A C C C C C
WideMatch + 
Harmony SGB
1 pt./A + 0.45-0.6
oz./A C C C C C
WideMatch + MCPA 
EsterF
1 pt./A + 0.5-0.75 
pt./A C C C C C
*C = Control; S = Suppression (indicates “Partial Control” which means significant activity but not always 
at a level generally considered acceptable for commercial weed control).
AOther products that contain equivalent active ingredient(s) and used at the same active ingredient rate(s) 
as the broadleaf herbicide tank-mix partner listed in this table may be used. 
BAddition of surfactants is not required.
CDO NOT exceed 0.8 pt./A of Bronate Advanced in a tank mix for control of Italian (annual) ryegrass, green 
foxtail, or yellow foxtail.
DDO NOT exceed 1.25 pt./A of Buctril in a tank mix for control of Italian (annual) ryegrass, green foxtail, or 
yellow foxtail.
EDO NOT exceed 0.6 oz./A of Harmony SG + 0.8 pt./A of Bronate Advanced for Italian ryegrass control.
FAssume 3.7 lb. ae/gal. product.
GStarane + Sword Herbicide, EPA Reg. No. 62719-307.

-16-
When tank mixing, add the broadleaf herbicide(s) to the spray tank first followed by 
Axial XL Herbicide.
Precaution: Temporary crop injury may occur with tank mixes under extreme weather 
conditions or when the crop is suffering from stress due to inadequate or abnormally high 
moisture levels or extreme temperatures
.
Note: Tank mixing is not recommended with any chemical additives, pesticides, or 
fertilizers that are not recommended on this label or other Syngenta labeling or 
recommendations made by Syngenta as reduced annual grass control and/or crop injury 
may occur. Herbicides not listed for tank mixing on this Axial XL label, or other Syngenta 
labeling or recommendations made by Syngenta may be applied sequentially. For 
optimum results, apply Axial XL Herbicide first and allow at least 4 days after application 
of Axial XL Herbicide before applying these herbicides sequentially.
Tank-Mix Application with Tilt Fungicide
Axial XL Herbicide may be tank mixed with Tilt Fungicide for annual grass and disease 
control. Apply Axial XL Herbicide at 16.4 fl. oz./A in a tank mix with Tilt Fungicide at 
labeled use rates. Refer to the Tilt Fungicide label for specific use directions, application 
rates, restrictions, and a list of diseases controlled.
Tank-Mix Application with Quilt Fungicide
Axial XL Herbicide may be tank mixed with Quilt Fungicide for annual grass control and 
early season disease suppression. Apply Axial XL Herbicide at 16.4 fl. oz./A in a tank mix 
with Quilt Fungicide at 7 fl. oz./A. Refer to the Quilt Fungicide label for specific use 
directions, restrictions, and a list of diseases suppressed and/or controlled. Note: Under 
certain environmental conditions, tank mixes of Quilt Fungicide plus herbicides may 
cause crop injury.
Tank-Mix Application with Warrior II with Zeon Technology
Axial XL Herbicide may be tank mixed with Warrior II with Zeon Technology for annual 
grass and insect control. Apply Axial XL Herbicide at 16.4 fl. oz./A in a tank mix with 
Warrior II with Zeon Technology at labeled use rates. Refer to the Warrior II with Zeon 
Technology label for specific use directions, application rates, restrictions, and a list of 
insects controlled.
Tank-Mix Application with Karate with Zeon Technology
Axial XL Herbicide may be tank mixed with Karate with Zeon Technology for annual grass 
and insect control. Apply Axial XL Herbicide at 16.4 oz./A in a tank mix with Karate with 
Zeon Technology at labeled use rates. Refer to the Karate with Zeon Technology label 
for specific use directions, application rates, restrictions, and a list of insects controlled.

-17-
Mixtures with Liquid Nitrogen Fertilizers
Axial XL Herbicide may be mixed in a spray solution containing up to 50% liquid nitrogen 
fertilizer. Add Axial XL Herbicide to the water first. Mix thoroughly, then add the liquid 
nitrogen fertilizer in an amount no greater than 50% of the final volume. Note: Under 
certain environmental conditions, mixtures of liquid nitrogen fertilizers as a partial carrier 
may cause crop burn.
When using Axial XL Herbicide with listed herbicide tank-mix partners, consult the label of 
the partner product and follow any additional instructions or restrictions on that label 
which relate to mixture with liquid nitrogen fertilizers.
STORAGE AND DISPOSAL
DO NOT contaminate water, food, or feed by storage or disposal.
Pesticide Storage
Store in a cool, dry place. DO NOT store near seeds, fertilizers, or foodstuffs.
Pesticide Disposal
Pesticide wastes are toxic. Improper disposal of excess pesticides, spray mixture, or 
rinsate is a violation of Federal law. If these wastes cannot be disposed of by use 
according to label instructions, contact your State Pesticide or Environmental Control 
Agency, or the Hazardous Waste representative at the nearest EPA Regional Office for 
guidance.
Container Handling
For containers equal to or less than 5 gallons:
Non-refillable container. DO NOT reuse or refill this container. Offer for recycling if 
available. Triple rinse container (or equivalent) promptly after emptying. Triple rinse as 
follows: empty the remaining contents into application equipment or a mix tank and 
drain for 10 seconds after the flow begins to drip. Fill the container ¼ full with water and 
recap. Shake for 10 seconds. Pour rinsate into application equipment or a mix tank or 
store rinsate for later use or disposal. Drain for 10 seconds after the flow begins to drip. 
Repeat this procedure two more times.
For containers greater than 5 gallons: Refillable container. Refill this container with 
pesticide only. DO NOT use this container for any other purpose. Cleaning the 
container before final disposal is the responsibility of the person disposing of the 
container. Cleaning before refilling is the responsibility of the refiller. To clean 
container before final disposal, empty the remaining contents from this container into 
application equipment or mix tank. Fill the container about 10 percent full with water. 
Agitate vigorously or recirculate water with the pump for 2 minutes. Pour or pump

-18-
rinsate into application equipment or rinsate collection system. Repeat this rinsing 
procedure two more times. Then offer for recycling if available or puncture and dispose 
of in a sanitary landfill, or by incineration, or, if allowed by state and local authorities, by 
burning. If burned, stay out of smoke. If the container is damaged, leaking, or obsolete, 
contact Syngenta Crop Protection, LLC, at 1-800-888-8372. 
For minor spills, leaks, etc., follow all precautions indicated on this label and clean up 
immediately. Take special care to avoid contamination of equipment and facilities during 
cleanup procedures and disposal of wastes. In the event of a major spill, fire, or other 
emergency, call 1-800-888-8372, day or night.
CONTAINER IS NOT SAFE FOR FOOD, FEED, OR DRINKING WATER!
Amber®, Axial®, Discover®, Karate® with Zeon Technology™, Peak®, Pulsar™,
Orion™, Quilt®, Tilt®, Warrior II with Zeon Technology®, the ALLIANCE FRAME, the 
SYNGENTA Logo and the PURPOSE ICON are Trademarks of a Syngenta Group 
Company.
Affinity™, Ally®, Express®, Finesse®, Harmony®, and Viton® trademarks of E.I. du 
Pont de Nemours and Company
Buctril®, Bronate®, and Huskie™ trademarks of Bayer CropScience
Curtail™ M, Starane®, Starane® + Sword®, Stinger® and WideMatch™ trademarks of 
Dow AgroSciences, LLC
Hat Trick® trademark of Loveland Products, Inc.
©20XX Syngenta
For non-emergency (e.g., current product information), call
Syngenta Crop Protection at 1-800-334-9481
Manufactured for:
Syngenta Crop Protection, LLC
P.O. Box 18300
Greensboro, North Carolina 27419-8300
Axial XL 1256 MAS 0813 AMEND-B.DEC2020-CL - di - 4/25/2022
000100-01256.20201215B.Axial_XL.AMEND.DEC2020-CL