crop-chem-docs/corpus/epa_ppls/100-1313.md

# QUADRIS TOP FUNGICIDE

- EPA Reg No: **100-1313**
- Registrant: SYNGENTA CROP PROTECTION, LLC
- Signal word: Caution
- Active ingredients: Azoxystrobin (18.2%); Difenoconazole (11.4%)
- Label accepted: 2019-12-16
- Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000100-01313-20191216.pdf

---
December 16, 2019
Subject:
Dear Mr. Kyaw:
Fast Track Label Acceptable v.20150320
OFFICE OF CHEMICAL SAFETY
AND POLLUTION PREVENTION
The amended label referred to above, submitted in connection with registration under the Federal 
Insecticide, Fungicide and Rodenticide Act, as amended, is acceptable. This approval does not 
affect any conditions that were previously imposed on this registration. You continue to be 
subject to existing conditions on your registration and any deadlines connected with them.
A stamped copy of your labeling is enclosed for your records. This labeling supersedes all 
previously accepted labeling. You must submit one copy of the final printed labeling before you 
release the product for shipment with the new labeling. In accordance with 40 CFR 152.130(c), 
you may distribute or sell this product under the previously approved labeling for 18 months 
from the date of this letter. After 18 months, you may only distribute or sell this product if it 
bears this new revised labeling or subsequently approved labeling. “To distribute or sell” is 
defined under FIFRA section 2(gg) and its implementing regulation at 40 CFR 152.3.
Ricky Kyaw
Regulatory Product Manager
Syngenta Crop Protection, Inc. 
P. O. Box 18300
Greensboro, NC 27419
Label Amendment - Add Optional Language, to the Cranberry and Watercress 
Specific Directions for Use section
Product Name: Quadris® Top Fungicide
EPA Registration Number: 100-1313
Application Date: 02-04-2019
Decision Number: 548713
Should you wish to add/retain a reference to the company’s website on your label, then please be 
aware that the website becomes labeling under the Federal Insecticide Fungicide and Rodenticide 
Act and is subject to review by the Agency. If the website is false or misleading, the product 
would be misbranded and unlawful to sell or distribute under FIFRA section 12(a)(1)(E). 40 
CFR 156.10(a)(5) list examples of statements EPA may consider false or misleading. In addition, 
regardless of whether a website is referenced on your product’s label, claims made on the 
website may not substantially differ from those claims approved through the registration process. 
Therefore, should the Agency find or if it is brought to our attention that a website contains false 
or misleading statements or claims substantially differing from the EPA approved registration, 
the website will be referred to the EPA’s Office of Enforcement and Compliance.
w
UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 
WASHINGTON, DC 20460

Enclosure
Shaja B. Joyner, Product Manager 20 
Fungicide-Herbicide Branch
Registration Division 7505P
Your release for shipment of the product constitutes acceptance of these conditions. If these 
conditions are not complied with, the registration will be subject to cancellation in accordance 
with FIFRA section 6. If you have any questions, please contact Manjula Unnikrishnan by phone 
at 703-347-8520, or via email at unnikrishnan.maniula@epa.gov .
Page 2 of 2
EPAReg. No. 100-1313
Decision No. 548713

ACCEPTED
GROUP
Quadris Top® Fungicide
KEEP OUT OF REACH OF CHILDREN.
CAUTION
See additional precautionary statements and directions for use inside booklet.
EPA Reg. No. 100-1313
EPA Est.
_____gallons
Net Contents
Quadris Top Fungicide 
Page 1
11
3
*CAS No. 131860-33-8 
**CAS No. 119446-68-3
AZOXYSTROBIN
DIFENOCONAZOLE GROUP
FUNGICIDE
FUNGICIDE
..18.2%
..11.4%
70.4%
100.0%
Quadris Top Fungicide is formulated as a suspension concentrate (SC) containing 1.67 
lb of azoxystrobin active ingredient and 1.05 lb of difenoconazole active ingredient per 
gallon.
Active Ingredients; 
Azoxystrobin*.......
Difenoconazole**..
Other Ingredients: 
Total:
12/16/2019
LntUr th* Pederai Insecllcidt, Fungicide 
and Rxjdenrwde Act as amnded. far die 
pesticide registered under
100-1313

If swallowed
If on skin
If in eyes
PRECAUTIONARY STATEMENTS
Hazards to Humans and Domestic Animals
CAUTION
Personal Protective Equipment (PPE)
Applicators and other handlers must wear:
• Long-sleeved shirt and long pants
• Shoes plus socks
• Waterproof gloves
Have the produc 
doctor, or going for treatment.
Harmful if swallowed or absorbed through skin. Causes moderate eye irritation. Avoid 
contact with skin, eyes or clothing. Wear protective eyewear. Wash thoroughly with 
soap and water after handling and before eating, drinking, chewing gum. using tobacco, 
or using the toilet. Remove and wash contaminated clothing before reuse.
________________FIRST AID_____________________________
• Call a poison control center or doctor immediately for treatment 
advice.
• Have person sip a glass of water if able to swallow.
• Do not induce vomiting unless told to by a poison control center 
or doctor.
• Do not give anything by mouth to an unconscious person._____
• Take off contaminated clothing.
• Rinse skin immediately with plenty of water for 15-20 minutes.
• Call a poison control center or doctor for treatment advice.
• Hold eye open and rinse slowly and gently with water for 15-20 
minutes. Remove contact lenses, if present, after the first 5 
minutes, then continue rinsing eye.
• Call a poison control center or doctor for treatment advice. 
container or label with you when calling a poison control center or
QuadrisTop Fungicide
Page 2
HOT LINE NUMBER
For 24-Hour Medical Emergency Assistance (Human or Animal)
Or Chemical Emergency Assistance (Spill. Leak. Fire or Accident)
Call
1-800-888-8372

User Safety Requirements
Engineering Controls
User Safety Recommendations
Users should:
Environmental Hazards
Follow manufacturer’s instructions for cleaning/maintaining PRE. If no such instructions 
for washables exist, use detergent and hot water. Keep and wash PRE separately from 
other laundry.
Azoxystrobin is toxic to freshwater and estuarine/marine fish and aquatic invertebrates. 
Azoxystrobin can be persistent for several months or longer.
Difenoconazole is toxic to fish, mammals and aquatic invertebrates. Drift and runoff 
may be hazardous to estuarine/marine organisms in water adjacent to treated area.
When handlers use closed systems, enclosed cabs, or aircraft in a manner that meets 
the requirements listed in the Worker Protection Standard (WPS) for agricultural 
pesticides [40 CFR 170.240(d)(4-6)]. the handler PPE requirements may be reduced or 
modified as specified in the WPS. Human flagging is prohibited.
For terrestrial uses: Do not apply directly to water, or to areas where surface water is 
present or to intertidal areas below the mean high water mark. Drift and runoff may be 
hazardous to aquatic organisms in water adjacent to treated areas. Do not contaminate 
water when disposing of equipment washwater or rinsate.
• Remove clothing/PPE immediately if pesticide gets inside. Then wash thoroughly 
and put on clean clothing.
• Remove PPE immediately after handling this product. Wash the outside of gloves 
before removing. As soon as possible, wash thoroughly and change into clean 
clothing.
QuadrisTop Fungicide
Page 3

Groundwater Advisory
Surface Water Advisory
This product may impact surface water quality due to runoff of rain water. This is 
especially true for poorly draining soils and soils with shallow ground water. This 
product is classified as having a high potential for reaching surface water via runoff for 
several months or more after application. A level, well-maintained vegetative buffer 
strip between areas to which this product is applied and surface water features such as 
ponds, streams, and springswill reduce the potential loading of Azoxystrobin and a 
degradate of Azoxystrobin from runoff water and sediment. Runoff of this product will 
be reduced by avoiding applications when rainfall or irrigation is expected to occur 
within 48 hours.
Notify State and/or Federal authorities and Syngenta immediately if you observe any 
adverse environmental effects due to use of this product.
Azoxystrobin and a degradate of azoxystrobin are known to leach through soil into 
groundwater under certain conditions as a result of label use. This chemical may leach 
into groundwater if used in areas where soils are permeable, particularly where the 
water table is shallow.
QuadrisTop Fungicide
Page 4

DIRECTIONS FOR USE
AGRICULTURAL USE REQUIREMENTS
J
PRODUCT INFORMATION
Do not enter or allow worker entry into treated areas during the restricted-entry 
interval (REI) of 12 hours.
Quadris Top Fungicide is a broad-spectrum product containing two fungicides. It has 
preventative, systemic and curative properties and is specified for the control of many 
important plant diseases. Quadris Top Fungicide provides excellent disease control of 
many leaf spots and powdery mildews. Quadris Top Fungicide is applied as a foliar 
spray and can be used in block, alternating spray or tank-mix programs with other crop 
protection products. All applications need to be made according to the use directions 
that follow.
It is a violation of Federal Law to use this product in a manner inconsistent with its 
labeling.
Do not apply this product in a way that will contact workers or other persons, either 
directly or through drift. Only protected handlers may be in the area during application. 
For any requirements specific to your State or Tribe, consult the agency responsible for 
pesticide regulation.
Use this product only in accordance with its labeling and with the Worker Protection 
Standard, 40 CFR Part 170. This Standard contains requirements for the protection of 
agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of 
agricultural pesticides. It contains requirements for training, decontamination 
notification, and emergency assistance. It also contains specific instructions and 
exceptions pertaining to the statements on this label about personal protective 
equipment (PPE) and restricted-entry interval. The requirements in this box only apply 
to uses of this product that are covered by the Worker Protection Standard.
• Coveralls
• Chemical-resistant gloves made of any waterproof materials such as polyvinyl 
chloride, nitrile rubber or butyl rubber.
• Shoes plus socks
PPE required for early entry to treated areas that is permitted under the Worker 
Protection Standard and that involves contact with anything that has been treated, such 
as plants, soil, or water is:
Quadris Top Fungicide
Page 5

USE PRECAUTIONS AND RESTRICTIONS
ATTENTION
Quadris Top Fungicide is extremely phytotoxic to certain apple varieties.
DO NOT spray Quadris Top Fungicide where spray drift may reach apple trees.
AVOIDING SPRAY DRIFT IS THE RESPONSIBILITY OF THE APPLICATOR.
USE INFORMATION
AVOID SPRAY DRIFT. Extreme care must be used to prevent injury to apple trees 
(and apple fruit).
Application; Thorough coverage is necessary to provide good disease control. Make 
no more spray solution than is needed for application. Avoid spray overlap, as crop 
injury may occur.
Use of Adjuvants; Under certain weather conditions (particularly high temperatures) 
Quadris Top Fungicide in combination with high rates of silicone-based or oil containing 
(petroleum or crop) additives or adjuvants may cause injury. Do not exceed 0.125% 
adjuvant (v/v). Consult a Syngenta representative for more information concerning 
additives or adjuvants.
DO NOT use spray equipment which has been previously used to apply Quadris Top 
Fungicide to spray apple trees. Even trace amounts can cause unacceptable 
phytotoxicity to certain apple and crabapple varieties.
POLLINATOR ADVISORY STATEMENT; This product may adversely impact the forage 
and habitat of local pollinators, including the monarch butterfly (and its larvae), birds, or 
bats if reaches non-target areas. Protect pollinators by following label directions to 
minimize spray drift.
Adjuvants: When an adjuvant is to be used with this product, the use of an adjuvant 
that meets the standards of the Chemical Producers and Distributors Association 
(CPDA) adjuvant certification program is advised.
DO NOT spray when conditions favor drift beyond area intended for application. 
Conditions which may contribute to drift include thermal inversion, wind speed and 
direction, sprayer nozzle/pressure combinations, spray droplet size. etc. Contact your 
State Extension Agent for spray drift prevention guidelines in your area.
FAILURE TO FOLLOW DIRECTIONS AND PRECAUTIONS ON THIS LABEL MAY 
RESULT IN CROP INJURY, POOR DISEASE CONTROL, AND/OR ILLEGAL 
RESIDUES.
Quadris Top Fungicide 
Page 6

Precaution: A tank mixture with Dimethoate may cause crop injury.
Resistance Management
To delay fungicide resistance, take one or more of the following steps:
On fresh market tomatoes, do not use adjuvants or tank mix Quadris Top Fungicide with 
any EC product.
11
3
Efficacy: Under certain conditions conducive to extended infection periods, use 
another registered fungicide for additional applications if the maximum amount of 
Quadris Top Fungicide has been used. If resistant isolates to Group 3 or Group 11 
fungicides are present, efficacy can be reduced for certain diseases. The higher rates 
in the rate range and/or shorter spray intervals may be required under conditions of 
heavy infection pressure, with highly susceptible varieties, or when environmental 
conditions are conducive to disease.
For resistance management, please note that Quadris Top Fungicide contains both 
azoxystrobin, a strobilurin fungicide in Group 11 and difenoconazole, a triazole fungicide 
in Group 3. Any fungal population may contain individuals naturally resistant to either or 
both of the active ingredients in Quadris Top Fungicide and other Group 11 or Group 3 
fungicides. A gradual or total loss of pest control may occur over time if these 
fungicides are used repeatedly in the same fields. Appropriate resistance-management 
strategies need to be followed.
• Apply a maximum of 4 sprays during one crop cycle.
• Apply no more than 2 sequential applications unless otherwise stated in the crop 
section.
• Rotate the use of Quadris Top Fungicide or other Group 11 and 3 fungicides within a 
growing year sequence with different groups that control the same pathogens.
• Use tank mixtures with fungicides from a different group that are equally effective on 
the target pest when such use is permitted. Use at least the minimum application rate
AZOXYSTROBIN 
DIFENOCONAZOLE
GROUP
GROUP
FUNGICIDE
FUNGICIDE
Quadris Top Fungicide 
Page 7
Integrated Pest Management (IPM): Quadris Top Fungicide needs to be integrated 
into an overall disease and pest management strategy whenever the use of a fungicide 
is required. Cultural practices known to reduce disease development need to be 
followed. Consult your local agricultural authorities for additional IPM strategies 
established for your area. Quadris Top Fungicide may be used in State Agricultural 
Extension advisory (disease forecasting) programs which specifies application timing 
based on environmental factors favorable for disease development.

QuadrisTop Fungicide
Page 8
as labeled by the manufacturer.
• Adopt an integrated disease management program for fungicide use that includes 
scouting, uses historical information related to pesticide use, and crop rotation, and 
which considers host plant resistance, impact of environmental conditions on disease 
development, disease thresholds, as well as cultural, biological and other chemical 
control practices.
• Where possible, make use of predictive disease models to effectively time fungicide 
applications. Note that using predictive models alone is not sufficient to manage 
resistance.
• Monitor treated fungal populations for resistance development.
• Contact your local extension specialist or certified crop advisor for any additional 
pesticide resistance-management and/or IPM directions for specific crops and 
pathogens.
• For further information or to report suspected resistance contact Syngenta Crop 
Protection at 1-866-796-4368. You can also contact your pesticide distributor or 
university extension specialist to report resistance.

Rotational Crops: Please see the following table for the crop rotational restrictions:
0 days
30 days
Crop Resistance: Plant resistance has been found to be acceptable for all crops on 
the label, however, not all possible tank-mix combinations have been tested under all
Planting Time From Last 
Quadris Top Fungicide Application
QuadrisTop Fungicide
Page 9
365 days
60 days
Rotational Crops____________________
Artichoke, Globe
Bean and Pea, Dried Shelled Subgroup 6C
Berry, Bushberry Subgroup 13-07B
Berry, Low Growing, Subgroup 13-07G 
Brassica (Cole) Leafy Vegetables 
Bulb Vegetables, bulb onion Subgroup 3-
07A and green onion Subgroup 3-07B
Carrots
Chickpeas
Citrus fruit Crop Group 10-10
Cotton Subgroup 20C
Cucurbit Vegetables Crop Group 9
Fruit, small, vine climbing Subgroup 13- 
07F, except fuzzy kiwifruit
Fruiting Vegetables Crop Group 8-10
Ginseng
Guava
Papaya
Pepper
Potatoes
Rice
Soybeans
Stone fruit Crop Group 12-12
Strawberries
Sugar Beets
Tree nuts Crop Group 14-12
Tomatoes
Tuberous & Corm Vegetable Subgroup 1C
Watercress
Wild rice____________________________
Cereals (Wheat, Barley, Triticale)
Oats
Rye
Root and Tuber Vegetables, Crop Group 1 
(except Carrot, Sugar Beet, and Tuberous
Corm Vegetable Subgroup 1C)__________
Buckwheat
Millet_______________________________
All Other Crops Intended for Food and Feed

SPRAY DRIFT MANAGEMENT
MANDATORY SPRAY DRIFT
Aerial Applications
Groundboom Applications
QuadrisTop Fungicide
Page 10
conditions. When possible, it is advised to test the combinations on a small portion of 
the crop to ensure that a phytotoxic response will not occur as a result of application. 
See USE PRECAUTIONS AND RESTRICTIONS regarding apple phytotoxicity.
Greenhouse Use: For resistance management, do not use Quadris Top Fungicide for 
transplant production.
• User must only apply with the release height recommended by the manufacturer, but 
no more than 4 feet above the ground or crop canopy.
• Applicators are required to use a medium or coarser droplet size (ASABE S572.1).
• Do not apply when wind speeds exceed 15 miles per hour at the application site.
• Do not apply during temperature inversions.
To avoid spray drift, do not apply when conditions favor drift beyond the target area. 
The interaction of many equipment and weather related factors determine the potential 
for spray drift. AVOIDING SPRAY DRIFT AT THE APPLICATION SITE IS THE 
RESPONSIBILITY OF THE APPLICATOR AND THE GROWER. More information on 
managing spray drift can be found on the Syngenta Crop Protection website under 
Stewardship (http://www.svngenta-us.com/practicing-stewardship/responsible-pesticide- 
application).
• Do not release spray at a height greater than 10 ft above the ground or crop canopy, 
unless a greater application height is necessary for pilot safety.
• Applicators are required to select nozzles that deliver medium to coarse spray 
droplets in accordance with ASABE Standard S572.1.
• Do not apply when wind speeds exceed 15 mph at the application site. If the 
windspeed is greater than 10 mph, the boom length must be 65% or less of the 
wingspan for fixed wing aircraft and 75% or less of the rotor diameter for helicopters. 
Otherwise, the boom length must be 75% or less of the wingspan for fixed-wing 
aircraft and 90% or less of the rotor diameter for helicopters.
• Applicators must use % swath displacement upwind at the downwind edge of the 
field.
• Do not apply during temperature inversions.

SPRAY DRIFT ADVISORIES
IMPORTANCE OF DROPLET SIZE
Controlling Droplet Size - Groundboom
Controlling Droplet Size - Aircraft
BOOM HEIGHT - Ground Boom
RELEASE HEIGHT - Aircraft
• Higher release heights increase the potential for spray drift.
SHIELDED SPRAYERS
• For ground equipment, the boom should remain level with the crop and have 
minimal bounce.
THE APPLICATOR IS RESPONSIBLE FOR AVOIDING OFF-SITE SPRAY 
DRIFT.
BE AWARE OF NEARBY NON-TARGET SITES AND ENVIRONMENTAL 
CONDITIONS.
QuadrisTop Fungicide
Page 11
• An effective way to reduce spray drift is to apply large droplets. Use the largest 
droplets that provide target pest control. While applying larger droplets will 
reduce spray drift, the potential for drift will be greater if applications are made 
improperly or under unfavorable environmental conditions.
• Shielding the boom or individual nozzles can reduce spray drift. Consider using 
shielded sprayers. Verify that the shields are not interfering with the uniform 
deposition of the spray on the target area.
• Adjust Nozzles - Follow nozzle manufacturers recommendations for setting up 
nozzles. Generally, to reduce fine droplets, nozzles should be oriented parallel 
with the airflow in flight.
• Volume - Increasing the spray volume so that larger droplets are produced will 
reduce spray drift. Use the highest practical spray volume for the application. If a 
greater spray volume is needed, consider using a nozzle with a higher flow rate.
• Pressure - Use the lowest spray pressure recommended for the nozzle to 
produce the target spray volume and droplet size.
• Spray Nozzle - Use a spray nozzle that is designed for the intended application. 
Consider using nozzles designed to reduce drift.

TEMPERATURE AND HUMIDITY
TEMPERATURE INVERSIONS
WIND
MIXING AND APPLICATION METHODS
Spray Equipment
Nozzles
Pump
(1)
• Use a pump with capacity to: 
Maintain 35-40 psi at nozzles.
• When making applications in hot and dry conditions, use larger droplets to 
reduce effects of evaporation.
• Drift potential is high during a temperature inversion. Temperature inversions are 
characterized by increasing temperature with altitude and are common on nights 
with limited cloud cover and light to no wind. The presence of an inversion can be 
indicated by ground fog or by the movement of smoke from a ground source or 
an aircraft smoke generator. Smoke that layers and moves laterally in a 
concentrated cloud (under low wind conditions) indicates an inversion, while 
smoke that moves upward and rapidly dissipates indicates good vertical air 
mixing. Avoid applications during temperature inversions.
• Equip sprayers with nozzles that provide accurate and uniform application.
• Use the same size nozzles uniformly spaced across the boom.
• Calibrate sprayer before use.
• Use screens to protect the pump and to prevent nozzles from clogging.
• On suction side of pump use screens that are 16-mesh or coarser.
• Do not place a screen in the recirculation line.
• Use 50-mesh or coarser screens between the pump and boom, and where required, 
at the nozzles.
• Check nozzle manufacturer’s directions.
• Drift potential increases at wind speeds. AVOID APPLICATIONS DURING
GUSTY WIND CONDITIONS.
• Applicator need to be familiar with local wind patterns and terrain that could affect 
spray drift.
QuadrisTop Fungicide
Page 12

(2)
Mixing Instructions
Quadris Top Fungicide Alone (No Tank Mix)
Mixing in the Spray Tank
• Add %-% of the required amount of water to the spray or mixing tank.
Quadris Top Fungicide 
Page 13
For more information on spray equipment and calibration, consult sprayer 
manufacturer’s and state directions. For specific local directions and spray schedules, 
consult the current state agricultural directions.
Tank Mixtures: All directions for use, crops/sites, use rates, dilution rates, precautions, 
and limitations which appear on the tank-mix product label must be observed. The label 
dosage for the tank-mix partner is not to be exceeded, and the most restrictive label 
precautions and limitations are to be followed.
• Add of the required amount of water to the spray or mixing tank.
• With the agitator running, add Quadris Top Fungicide to the tank.
• Continue agitation while adding the remainder of the water.
• Begin application of the spray solution after Quadris Top Fungicide has completely 
dispersed into the mix water.
• Maintain agitation until all of the mixture has been sprayed.
Provide sufficient agitation in tank to keep mixture in suspension - this 
requires recirculation of 10% of tank volume per minute.
• Use a jet agitator or liquid sparge tube for agitation.
• Do not air sparge.
• Quadris Top Fungicide is a suspension concentrate (SC) formulation.
• Prepare no more spray mixture than is required for the immediate operation.
• Thoroughly clean spray equipment before using this product.
• Agitate the spray solution before and during application.
• Rinse spray tank thoroughly with clean water after each day’s use and dispose of 
pesticide rinsate by application to an already treated area.
Quadris Top Fungicide + Tank Mixtures: Quadris Top Fungicide is usually 
compatible with tank-mix partners listed on this label. To determine the physical 
compatibility of Quadris Top Fungicide with other products, use a jar test. Using a quart 
jar, add the proportionate amounts of the products to 1 qt of water. Add wettable 
powders and water dispersible granular products first, then liquid flowables, and 
emulsifiable concentrates last. After thoroughly mixing, let stand for at least 5 minutes. 
If the combination remains mixed or can be remixed readily, it is physically compatible. 
Once compatibility has been proven, use the same procedure for adding required 
ingredients to the spray tank.

Application Instructions
Ground Application
Aerial Application
QuadrisTop Fungicide
Page 14
Quadris Top Fungicide may be applied with many types of spray equipment commonly 
used for making ground and aerial applications. Proper adjustments and calibration of 
spraying equipment to give good canopy penetration and coverage is essential for good 
disease control.
• With the agitator running, add the tank-mix partner(s) into the tank in the same order 
as described above.
• Allow the material to completely dissolve and disperse into the mix water. Continue 
agitation while adding the remainder of the water and Quadris Top Fungicide to the 
spray tank.
• Allow Quadris Top Fungicide to completely disperse.
• Spray the mixture with the agitator running.
• Observe all directions for use, crops/sites, use rates, dilution ratios, precautions, and 
limitations which appear on the tank mix product label.
• Label dosage rate must not be exceeded, and the most restrictive label precautions 
and limitations must be followed.
• This product must not be mixed with any product which prohibits such mixing.
• It is the pesticide user’s responsibility to ensure that all products are registered for 
the intended use. Read and follow the applicable restrictions and limitations and 
directions for use on all product labels involved in tank mixing. Users must follow the 
most restrictive directions for use and precautionary statements of each product in 
the tank mixture.
• Use only on crops where aerial applications are indicated.
• Thorough coverage is necessary to provide good disease control.
• Apply in a minimum of 5 gallons of water per acre unless specified otherwise.
• DO NOT apply under conditions when uniform coverage cannot be obtained or when 
excessive spray drift may occur.
• DO NOT apply directly to humans or animals.
• DO NOT apply through any ultra-low volume (ULV) spray system.
• Apply in a minimum of 10 gal of water per acre, unless specified otherwise.
• DO NOT apply through any ultra-low volume (ULV) spray system.
• Thorough coverage is necessary to provide good disease control.

ATTENTION
Quadris Top Fungicide is extremely phytotoxic to certain apple varieties.
Extreme care must be used to prevent injury to apple trees (and apple fruit).
DO NOT spray Quadris Top Fungicide where spray drift may reach apple trees.
Application Through Irrigation Systems (Chemigation)
Operating Instructions
1.
2.
3.
The system must contain a functional check-valve, vacuum relief valve, and low 
pressure drain appropriately located on the irrigation pipeline to prevent water­
source contamination from backflow.
The pesticide injection pipeline must also contain a functional, normally closed, 
solenoid-operated valve located on the intake side of the injection pump and
DO NOT use spray equipment which has been previously used to apply Quadris Top 
Fungicide to spray apple trees. Even trace amounts can cause unacceptable 
phytotoxicity to certain apple and crabapple varieties.
DO NOT spray when conditions favor drift beyond area intended for application. 
Conditions which may contribute to drift include thermal inversion, wind speed and 
direction, sprayer nozzle/pressure combinations, spray droplet size, etc. Contact your 
State Extension Agent for spray drift prevention guidelines in your area.
The pesticide injection pipeline must contain a functional, automatic, quick­
closing check-valve to prevent the flow of fluid back toward the injection pump.
• Use only on crops for which chemigation is specified on this label.
• Apply this product only through center pivot, solid set, hand move, or moving wheel 
irrigation systems. DO NOT apply this product through any other type of irrigation 
system.
• Crop injury, lack of effectiveness, or illegal pesticide residues in the crop can result 
from non-uniform distribution of treated water.
• Apply in 0.1-0.25 inches/acre. Excessive water may reduce efficacy.
• If you have questions about calibration, you must contact State Extension Service 
specialists, equipment manufacturers, or other experts.
• DO NOT connect an irrigation system (including greenhouse systems) used for 
pesticide application to a public water system, unless the pesticide label-prescribed 
safety devices for public water systems are in place.
• A person knowledgeable of the chemigation system and responsible for its 
operation, or under the supervision of the responsible person, shall shut the system 
down and make necessary adjustments if the need arise.
Quadris Top Fungicide 
Page 15

4.
5.
6.
7.
Center Pivot Irrigation Equipment
QuadrisTop Fungicide
Page 16
The system must contain functional interlocking controls to automatically shut off 
the pesticide injection pump when the water pump motor stops.
The irrigation line or water pump must include a functional pressure switch which 
will stop the water pump motor when the water pressure decreases to the point 
where pesticide distribution is adversely affected.
connected to the system interlock to prevent fluid from being withdrawn from the 
supply tank when the irrigation system is either automatically or manually shut 
down.
Notes: (1) Use only with drive systems which provide uniform water distribution. 
(2) DO NOT use end guns when chemigating Quadris Top Fungicide through center 
pivot systems because of non-uniform application.
Systems must use a metering pump, such as a positive displacement injection 
pump (e.g., diaphragm pump), effectively designed and constructed of materials 
that are compatible with pesticides and capable of being fitted with a system 
interlock.
DO NOT apply when wind speed favors drift beyond the area intended for 
treatment.
• Determine the size of the area to be treated.
• Determine the time required to apply 78-% inch of water over the area to be treated 
when the system and injection equipment are operated at normal pressures as 
directed by the equipment manufacturer. When applying Quadris Top Fungicide 
through irrigation equipment use the lowest obtainable water volume while 
maintaining uniform distribution. Run the system at 80-95% of the manufacturer’s 
rated capacity.
• Using water, determine the injection pump output when operated at normal line 
pressure.
• Determine the amount of Quadris Top Fungicide required to treat the area covered 
by the irrigation system.
• Add the required amount of Quadris Top Fungicide and sufficient water to meet the 
injection time requirements to the solution tank.
• Make sure the system is fully charged with water before starting injection of the 
Quadris Top Fungicide solution. Time the injection to last at least as long as it takes 
to bring the system to full pressure.

Solid Set, Hand Move, and Moving Wheel Irrigation Equipment
QuadrisTop Fungicide
Page 17
• Maintain constant solution tank agitation during the injection period.
• Continue to operate the system until the Quadris Top Fungicide solution has cleared 
the sprinkler head.
• Determine the acreage covered by the sprinklers.
• Fill injector solution tank with water and adjust flow rate to use the contents over a
20- to 30-minute interval. When applying Quadris Top Fungicide through irrigation 
equipment use the lowest obtainable water volume while maintaining uniform 
distribution.
• Determine the amount of Quadris Top Fungicide required to treat the area covered 
by the irrigation system.
• Add the required amount of Quadris Top Fungicide into the same quantity of water 
used to calibrate the injection period.
• Operate the system at the same pressure and time interval established during the 
calibration.
• Stop injection equipment after treatment is completed. Continue to operate the 
system until the Quadris Top Fungicide solution has cleared the last sprinkler head.

SPECIFIC INSTRUCTIONS FOR PUBLIC WATER SYSTEMS
1.
2.
3.
4.
5.
6.
7.
QuadrisTop Fungicide
Page 18
The system must contain functional interlocking controls to automatically shut off 
the pesticide injection pump when the water pump motor stops, or in cases 
where there is no water pump, when the water pressure decreases to the point 
where pesticide distribution is adversely affected.
DO NOT apply when wind speed favors drift beyond the area intended for 
treatment.
The pesticide injection pipeline must contain a functional, normally closed, 
solenoid-operated valve located on the intake side of the injection pump and 
connected to the system interlock to prevent fluid from being withdrawn from the 
supply tank when the irrigation system is either automatically or manually shut 
down.
Chemigation systems connected to public water systems must contain a 
functional, reduced-pressure zone, back-flow preventer (RPZ) or the functional 
equivalent in the water supply line upstream from the point of pesticide 
introduction. As an option to the RPZ. the water from the public water system 
needs to be discharged into a reservoir tank prior to pesticide introduction. There 
shall be a complete physical break (air gap) between the outlet end of the fill pipe 
and the top or overflow rim of the reservoir tank of at least twice the inside 
diameter of the fill pipe.
Public water system means a system for the provision to the public of piped 
water for human consumption if such system has at least 15 service connections 
or regularly serves an average of at least 25 individuals daily at least 60 days out 
of the year.
The pesticide injection pipeline must contain a functional, automatic, quick­
closing check valve to prevent the flow of fluid back toward the injection pump.
Systems must use a metering pump, such as a positive displacement injection 
pump (e.g., diaphragm pump) effectively designed and constructed of materials 
that are compatible with pesticides and capable of being fitted with a system 
interlock.

SPECIFIC DIRECTIONS FOR USE
Anthracnose 
{Colletotrichum 
acutatum}
Shot Hole
{Wilsonomyces 
carpophilus')
Blossom Blight 
{Monilinia spp.)
Leaf Blight 
{Seimatosporium 
lichenicola)
Leaf Rust 
{Tranzschelia
discolor)
QuadrisTop Fungicide
Page 19
If monitoring or history indicates the presence of 
Alternaria, apply 14 fl oz/A of Quadris Top Fungicide 
in the late spring (mid-April to beginning of May) and 
then repeat the treatment 2-3 weeks later.
The addition of a spreading/penetrating type adjuvant 
such as a non-ionic based surfactant or crop oil 
concentrate or blend is advised.
[Optional language if label has a rate range". If 
disease pressure is high, use the highest rate.]
For all other diseases, begin applications prior to 
disease onset when conditions are conducive for 
disease. Apply Quadris Top Fungicide on a 14- to 21- 
day schedule making no more than 2 sequential 
applications before alternating to another fungicide 
with a non-Qol (Group 11) mode of action.
[Optional language if label has a single rate and 
interval range: If disease pressure is high, use the 
shortest interval.]
_________________Use Directions________________
For blossom blight, begin applications at early bloom 
and continue through petal fall. Make no more than 2 
sequential applications before alternating to another 
fungicide with a different mode of action.
[Optional language if label has a rate range and 
interval range". If disease pressure is high, use the 
_____________________________I___________ shortest interval and highest rate.]_________________ 
*8 fl oz product/A contains 0.10 lb azoxystrobin/A and 0.07 lb difenoconazole/A.
*12 fl oz product/A contains 0.16 lb azoxystrobin/A and 0.10 lb difenoconazole/A
*14 fl oz product/A contains 0.18 lb azoxystrobin/A and 0.11 lb difenoconazole/A._________________
Application: For best results, sufficient water volume must be used to provide thorough coverage. 
Quadris Top Fungicide can be applied by ground or aerial application. Use a minimum of 15 gal/A of 
water for ground applications. For aerial applications, use a minimum of 10 gal/A of water.
Scab
{Venturia 
carpophilia)
Use Rate 
fl oz 
product/A
8-14*
Crop 
Almonds
Target Diseases
Alternaria Leaf 
Spot 
{A. alternate)

Specific Use Restrictions:
1) Maximum Single Application Rate: Do not exceed the maximum rate listed in the table.
2) Minimum Application Interval: 14 days
3) Do not apply more than 4 applications per year at the highest rate.
4) Do not apply more than 56 fl oz/A/year of Quadris Top Fungicide (0.73 lb azoxystrobin and 0.46 
lb difenoconazole).
5) Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
6) Do not apply more than 1.5 lb ai/A/year of azoxystrobin-containing products.
7) Do not apply within 28 days of harvest (28-day PHI).
____________Use Directions___________ 
Begin applications prior to disease onset 
when conditions are conducive for 
disease. Apply Quadris Top Fungicide on 
a 14-day schedule making no more than 2 
sequential applications before alternating 
to another fungicide with a different mode 
of action._____________________________
*10 fl oz product/A contains 0.13 lb azoxystrobin/A and 0.08 lb difenoconazole/A. 
*14 fl oz product/A contains 0.18 lb azoxystrobin/A and 0.11 lb difenoconazole/A._________________
Application: For best results, sufficient water volume must be used to provide thorough coverage. 
Quadris Top Fungicide can be applied by ground, chemigation, or aerial application. For ground 
applications, apply in 50-200 gallons of water per acre to obtain coverage without excessive runoff. 
For aerial applications, use a minimum of 10 gal/A of water. For chemigation, apply in 0.1-0.25 
inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy.__________
Specific Use Restrictions:
1) Maximum Single Application Rate: Do not exceed the maximum rate listed in the table.
2) Minimum Application Interval: 14 days
3) Do not apply more than 4 applications per year at the highest rate.
4) Do not apply more than 56 fl oz/A/year of Quadris Top Fungicide (0.73 lb azoxystrobin and 0.46 
lb difenoconazole).
5) Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
6) Do not apply more than 1.5 lb ai/A/year of azoxystrobin-containing products.
7) Do not apply Quadris Top Fungicide within 3 days of harvest (3-day PHI).
Quadris Top Fungicide 
Page 20
______ Crop 
Artichoke, Globe
Target Diseases
Ramularia Leaf Spot 
Ramularia Bud Spot 
(R cynarae)
Use Rate 
fl oz 
product/A
10-14*

See complete list 
below
____________Use Directions___________
Begin applications prior to disease onset 
when conditions are conducive for 
disease. Apply Quadris Top Fungicide on 
a 14-day schedule making no more than 2 
sequential applications before alternating 
to another fungicide with a different mode 
of action.
To be grown for 
bean, dried seed 
only.
See specific
directions for
soybeans and
chickpea__________ ____________________|_________________________________________________
*12 fl oz product/A contains 0.16 lb azoxystrobin/A and 0.10 lb difenoconazole/A
*14 fl oz product/A contains 0.18 lb azoxystrobin/A and 0.11 lb difenoconazole/A._________________
Application: For best results, sufficient water volume must be used to provide thorough coverage. 
Quadris Top Fungicide can be applied by ground, chemigation, or aerial application. Use a minimum 
of 15 gal/A of water for ground applications. For aerial applications, use a minimum of 10 gal/A of 
water. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may 
lead to a decrease in efficacy.______________________________________________________________
Complete List of Bean and Pea, dried shelled (except soybean) - Subgroup 6C: Dried cultivars 
of bean (Lupinus); bean (Phaseolus) (includes field bean, kidney bean, lima bean, navy bean, pinto 
bean, tepary bean); bean (Vigna) (includes adzuki bean, blackeyed pea, catjang, cowpea, crowder 
pea, moth bean, mung bean, rice bean, southern pea, urd bean); broad bean; guar; lablab bean; 
lentil; pea (Pisum) (includes field pea); pigeon pea___________ ________________________________
Specific Use Restrictions:
1) Maximum Single Application Rate: Do not exceed the maximum rate listed in the table.
2) Minimum Application Interval: 14 days
3) Do not apply more than 4 applications per year at the highest rate.
4) Do not apply more than 56 fl GzJNye&r of Quadris Top Fungicide (0.73 lb azoxystrobin and 0.46 
lb difenoconazole).
5) Do not apply more than 28 fl ozJNye&r of Quadris Top Fungicide (0.23 lb difenoconazole/A/year) 
for pea vines and hay.
6) Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
7) Do not apply more than 1.3 lb ai/A/year of azoxystrobin-containing products.
8) Do not feed or harvest cowpeas forage and hay.
9) Do not apply Quadris Top Fungicide within 14 days of harvest (14-day PHI).
Quadris Top Fungicide 
Page 21
Phaseolus 
Vigna 
Pisum 
Lupinus
______ Crop_____ 
Bean and Pea, 
Dried Shelled 
(except soybean) 
Subgroup 6C
Target Diseases
Anthranose 
{Colletotrichum 
lindemuthianum)
Alternaria leaf spot 
(A. alternata) 
Alternaria blight 
{Alternaria spp.) 
Ascochyta leaf and 
pod spot 
{Ascochyta spp.) 
Ascochyta blight 
{Mycosphaerella 
pinodes}
Cercospora leaf spot 
{Cercospora 
cruenta}
Use Rate 
fl oz 
product/A
12-14*

Blueberry For Monilinia and mummyberry, apply at or 
near flower bud swell and again at leaf bud 
swelling.
[Optional language if label has a single 
rate and interval range: If disease 
pressure is high, use the shortest interval.]
Apply Quadris Top Fungicide on a 7- to 
14-day schedule making no more than 2 
sequential applications before alternating 
to another fungicide with a different mode 
of action.
For other diseases, apply during early 
bloom.
[Optional language if label has a rate 
range'. If disease pressure is high, use the 
highest rate.]
____________Use Directions__________
Begin applications prior to disease onset 
when conditions are conducive for 
disease.
[Optional language if label has a rate 
range and interval range: If disease 
pressure is high, use the shortest interval
_______________________________________I___________ and highest rate.]______________________ 
*10 fl oz product/A contains 0.13 lb azoxystrobin/A and 0.08 lb difenoconazole/A.
*12 fl oz product/A contains 0.16 lb azoxystrobin/A and 0.10 lb difenoconazole/A 
*14 fl oz product/A contains 0.18 lb azoxystrobin/A and 0.11 lb difenoconazole/A.__________________
Application: For best results, sufficient water volume must be used to provide thorough coverage. 
Quadris Top Fungicide can be applied by ground or aerial application. Use a minimum of 15 gal/A of 
water for ground applications. For aerial applications, use a minimum of 10 gal/A of water.__________
Complete List of Bushberry Subgroup: Aronia berry; blueberry, highbush; blueberry, lowbush; 
buffalo currant: Chilean guava; cranberry, highbush; currant, black; currant, red; elderberry; European 
barberry; gooseberry; honeysuckle, edible; huckleberry; jostaberry; Juneberry (Saskatoon berry); 
lingonberry; native currant; salal; sea buckthorn; cultivars, varieties, and/or hybrids of these._________
Specific Use Restrictions:
1) Maximum Single Application Rate: Do not exceed the maximum rate listed in the table.
2) Minimum Application Interval: 7 days
3) Do not apply more than 4 applications per year at the highest rate.
4) Do not apply more than 56 fl oz/A/year of Quadris Top Fungicide (0.73 lb azoxystrobin and 0.46 
lb difenoconazole).
5) Do not apply more than 0.75 lb ai/A/year of azoxystrobin-containing products.
6) Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
7) Do not apply Quadris Top Fungicide within 7 days of harvest (7-day PHI).
Quadris Top Fungicide 
Page 22
______Crop_____
Berry,
Bushberry 
Subgroup 13-07B
Target Diseases 
Powdery mildew 
{Microsphaera alni) 
Anthracnose 
{Colletotrichum 
spp.)
Septoria leaf spot 
(S. albopunctata) 
Alternaria leaf spot 
{A.tenuissima}
Leaf rust 
{Pucciniastrum 
vaccinii} 
Monilinia blight and 
Mummyberry blight 
(A4. vaccinii- 
corymbosis}
Use Rate 
fl oz 
product/A
10-14*

QuadrisTop Fungicide
Page 23

strawberry
1)
2)
3)
4)
See complete list of 
low growing berries 
below.
5)
6)
7)
Powdery Mildew 
{Sphaerotheca 
macularis)
The addition of a spreading/penetrating 
type adjuvant such as a non-ionic based 
surfactant or crop oil concentrate or blend 
is advised.
___________Use Directions___________
Begin applications prior to disease onset 
when conditions are conducive for 
disease. Apply Quadris Top Fungicide on 
a 7- to 14-day schedule making no more 
than 2 sequential applications before 
alternating to another fungicide with a 
different mode of action.
[Optional language if label has a single 
rate and interval range: If disease 
pressure is high, use the shortest 
interval.]
Including all cultivars 
and/or hybrids of 
these
See separate 
instructions for 
cranberry.
Leaf Rust
{Phragmidium 
potentillae)
[Optional language if label has a rate 
range: If disease pressure is high, use 
the highest rate.]
Quadris Top Fungicide 
Page 24
Leaf Spot 
{Cercospora 
fragariae)
Use Rate 
fl oz 
product/ 
A
8-14*
_______ Crop_______ 
Berry, Low Growing, 
Subgroup 13-07G
Target Diseases
Anthracnose
{Colletotrichum
spp.)
[Optional language if label has a rate
range and interval range: If disease 
pressure is high, use the shortest interval
________________________________________I__________ and highest rate.]_____________________ 
*8 fl oz product/A contains 0.10 lb azoxystrobin/A and 0.07 lb difenoconazole/A.
*12 fl oz product/A contains 0.16 lb azoxystrobin/A and 0.10 lb difenoconazole/A 
*14 fl oz product/A contains 0.18 lb azoxystrobin/A and 0.11 lb difenoconazole/A._________________
Application: For best results, sufficient water volume must be used to provide thorough coverage. 
Quadris Top Fungicide can be applied by ground, chemigation, or aerial application. Use a minimum 
of 15 gal/A of water for ground applications. For aerial applications, use a minimum of 10 gal/A of 
water. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may 
lead to a decrease in efficacy.______________________________________________________________
Complete List of Additional Low Growing Berries: Bearberry; Bilberry; Blueberry, lowbush; 
Cloudberry; Lingonberry; Muntries; Partridgeberry; Strawberry; cultivars, varieties, and/or hybrids of 
these.___________________________________________________________________________________
Specific Use Restrictions:
Maximum Single Application Rate: Do not exceed the maximum rate listed in the table.
Minimum Application Interval: 7 days
Do not apply more than 4 applications per year at the highest rate.
Do not apply more than 56 fl oz/A/year of Quadris Top Fungicide (0.73 lb azoxystrobin and 0.46 
lb difenoconazole).
Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
Do not apply more than 1.0 lb ai/A/year of azoxystrobin-containing products.
Quadris Top Fungicide may be applied the day of harvest (0-day PHI).

QuadrisTop Fungicide
Page 25

Including all 
cultivars and/or 
hybrids of these
See additional 
crops below.
Anthracnose
{Colletotrichum 
higginsianum)
Powdery Mildew 
{Erysiphe polygoni}
The addition of a spreading/penetrating 
type adjuvant such as a non-ionic 
based surfactant or crop oil 
concentrate or blend is advised.
[Optional language if label has a single 
rate and interval range: If disease 
pressure is high, use the shortest 
interval.]
__________Use Directions_________
Begin applications prior to disease 
onset when conditions are conducive 
for disease. Apply Quadris Top 
Fungicide on a 7- to 14-day schedule, 
making no more than 1 application 
before alternating to another fungicide 
with a non-Qol (Group 11) mode of 
action.
[Optional language if label has a rate 
range and interval range'. If disease
pressure is high, use the shortest
________________________________________I_______________ interval and highest rate.]____________ 
*8 fl oz product/A contains 0.10 lb azoxystrobin/A and 0.07 lb difenoconazole/A.
*12 fl oz product/A contains 0.16 lb azoxystrobin/A and 0.10 lb difenoconazole/A
*14 fl oz product/A contains 0.18 lb azoxystrobin/A and 0.11 lb difenoconazole/A.____________________
Application: For best results, sufficient water volume must be used to provide thorough coverage.
Quadris Top Fungicide can be applied by ground, chemigation, or aerial application. Use a minimum of 
15 gal/A of water for ground applications. For chemigation, apply in 0.1-0.25 inches/A of water.
Chemigation with excessive water may lead to a decrease in efficacy.______________________________
Complete List of Brassica Leafy Vegetables: Broccoli; broccoli, Chinese (gai Ion); broccoli raab 
(rapini); Brussels sprouts; cabbage; cabbage, Chinese (bok choy); cabbage, Chinese (napa); cabbage, 
Chinese mustard(gai choy); cauliflower; cavalo broccolo; collards; kale; kohlrabi; mizuna; mustard 
greens; mustard spinach; rape greens; turnip greens____________________________________________
Specific Use Restrictions:
1) Maximum Single Application Rate: Do not exceed the maximum rate listed in the table.
2) Minimum Application Interval: 7 days
3) Do not apply more than 4 applications per year at the highest rate.
4) Do not apply more than 56 fl oz/A/year of Quadris Top Fungicide (0.73 lb azoxystrobin and 0.46 
lb difenoconazole).
5) Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
6) Do not apply more than 0.75 lb ai/A/year of azoxystrobin-containing products.
7) Do not apply within 1 day of harvest (1-day PHI).
Cercospora Leaf Spot 
(C. brassicicola)
[Optional language if label has a rate 
range'. If disease pressure is high, use 
the highest rate.]
Quadris Top Fungicide 
Page 26
Broccoli
Brussels Sprouts
Cabbage 
Cauliflower 
Collards
Kale
Mustard Greens
Use Rate 
fl oz 
product/A
8-14*
Target Diseases 
Alternaria Diseases 
{Alternaria spp.)
_____ Crop
Brassica (Cole) 
Leafy 
Vegetables 
Crop Group 5

QuadrisTop Fungicide
Page 27

Powdery Mildew
{Leveillula taurica)
Purple Blotch
{Alternaria porri)
The addition of a spreading/penetrating type 
adjuvant such as a non-ionic based surfactant or 
crop oil concentrate or blend is advised.
[Optional language if label has a rate range: If 
disease pressure is high, use the highest rate.]
______________Use Directions____________
Begin applications prior to disease onset when 
conditions are conducive for disease. Apply 
Quadris Top Fungicide on a 7- to 14-day 
schedule, making no more than 1 application 
before alternating to another fungicide with a 
non-Qol (Group 11) mode of action.
[Optional language if label has a single rate and 
interval range: If disease pressure is high, use 
the shortest interval.]
Crop
Bulb 
Vegetables
Cercospora Leaf
Spot
(C. duddiae)
Leaf Blotch
{Cladosporium allii- 
cepae)
Quadris Top Fungicide 
Page 28
Stemphyllium Leaf
Blight
(S. vesica hum}
Onion, Bulb 
Subgroup 3- 
07A
Garlic
Shallot
Onion, Green
Subgroup 3- 
07B
Leek 
Welsh
Onion Tops
Target Diseases 
Botrytis Leaf Blight 
(6. squamosa)
[Optional language if label has a rate range and 
interval range: If disease pressure is high, use 
the shortest interval and highest rate.]_________
*8 fl oz product/A contains 0.10 lb azoxystrobin/A and 0.07 lb difenoconazole/A
*12 fl oz product/A contains 0.16 lb azoxystrobin/A and 0.10 lb difenoconazole/A 
*14 fl oz product/A contains 0.18 lb azoxystrobin/A and 0.11 lb difenoconazole/A._________________
Application: For best results, sufficient water volume must be used to provide thorough coverage.
Quadris Top Fungicide can be applied by ground, chemigation, or aerial application. Use a minimum 
of 15 gal/A of water for ground applications. For chemigation, apply in 0.1-0.25 inches/A of water.
Chemigation with excessive water may lead to a decrease in efficacy.___________________________
Bulb onion subgroup 3-07A: Daylily, bulb; fritillaria, bulb; garlic, bulb; garlic, great-headed, 
bulb; garlic, serpent, bulb; lily, bulb; onion, bulb; onion, Chinese, bulb; onion, pearl; onion, 
potato, bulb; shallot, bulb; cultivars, varieties, and/or hybrids of these.
Green onion subgroup 3-07B: Chive, fresh leaves; chive, Chinese, fresh leaves; elegans 
hosta; fritillaria, leaves; kurrat; lady’s leek; leek; leek, wild; onion, Beltsville bunching; onion, 
fresh; onion, green; onion, macrostem; onion, tree, tops; onion, Welsh, tops; shallot, fresh 
leaves; cultivars, varieties, and/or hybrids of these.________________________________________
Specific Use Restrictions:
1) Maximum Single Application Rate: Do not exceed the maximum rate listed in the table.
2) Minimum Application Interval: 7 days
3) Do not apply more than 3 applications per year at the highest rate for green onions.
4) For green onions, do not apply more than 42 fl oz/A/year of Quadris Top Fungicide (0.55 lb 
azoxystrobin and 0.34 lb difenoconazole).
5) For green onions, do not apply more than 0.34 lb ai /A/year of difenoconazole-containing 
products.
6) Do not apply more than 4 applications per year at the highest rate for dry bulb onions.
7) For dry bulb onions, do not apply more than 56 fl oz/A/year of Quadris Top Fungicide (0.73 lb 
azoxystrobin and 0.46 lb difenoconazole).
8) For dry bulb onions, do not apply more than 0.46 lb ai/A/year of difenoconazole-containing
Use Rate 
fl oz 
product/A
8-14*

1)
2)
3)
4)
5)
6)
7)
Southern Blight 
{Sclerotium rolfsii)
Powdery Mildew 
{Erysiphe spp.)
products.
9) For the bulb vegetable crop group, do not apply more than 1.5 lb ai/A/year of azoxystrobin- 
containing products.
10) Do not apply within 7 days of harvest (7-day PHI).
The addition of a spreading/penetrating type 
adjuvant such as a non-ionic based surfactant or 
crop oil concentrate or blend is advised.
[Optional language if label has a rate range". If 
disease pressure is high, use the highest rate.]
______________Use Directions____________
Begin applications prior to disease onset when 
conditions are conducive for disease. Apply 
Quadris Top Fungicide on a 7- to 10-day 
schedule making no more than 2 sequential 
applications before alternating to another 
fungicide with a different mode of action.
[Optional language if label has a single rate and 
interval range: If disease pressure is high, use 
the shortest interval.]
[Optional language if label has a rate range and 
interval range". If disease pressure is high, use 
the shortest interval and highest rate.]
__________________________________I___________ For southern blight (white mold) use 14 fl oz/A. 
*8 fl oz product/A contains 0.10 lb azoxystrobin/A and 0.07 lb difenoconazole/A.
*12 fl oz product/A contains 0.16 lb azoxystrobin/A and 0.10 lb difenoconazole/A 
*14 fl oz product/A contains 0.18 lb azoxystrobin/A and 0.11 lb difenoconazole/A._________________
Application: For best results, sufficient water volume must be used to provide thorough coverage. 
Quadris Top Fungicide can be applied by ground, chemigation, or aerial application. Use a minimum 
of 15 gal/A of water for ground applications. For aerial applications, use a minimum of 10 gal/A of 
water. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may 
lead to a decrease in efficacy.______________________________________________________________
Specific Use Restrictions:
Maximum Single Application Rate: Do not exceed the maximum rate listed in the table.
Minimum Application Interval: 7 days
Do not apply more than 4 applications per year at the highest rate.
Do not apply more than 56 fl oz/A/year of Quadris Top Fungicide (0.73 lb azoxystrobin and 
0.46 lb difenoconazole).
Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
Do not apply more than 2.0 lb ai/A/year of azoxystrobin-containing products.
Do not apply within 7 days of harvest (7-day PHI).
Cercospora Leaf
Spot
{Cercospora 
carotae)
Quadris Top Fungicide 
Page 29
Use Rate 
fl oz 
product/A
8-14*
Crop 
Carrots
Target Diseases
Alternaria Leaf Blight 
{Alternaria dauci)

1)
2)
3)
4)
5)
6)
7)
Powdery Mildew 
(Leveillula tauhca)
QuadrisTop Fungicide
Page 30
The addition of a spreading/penetrating type 
adjuvant such as a non-ionic based surfactant or 
crop oil concentrate or blend is advised.
[Optional language if label has a rate range: If 
disease pressure is high, use the highest rate.]
______________Use Directions____________
Begin applications prior to disease onset when 
conditions are conducive for disease. Apply 
Quadris Top Fungicide on a 14-day schedule 
making no more than 2 sequential applications 
before alternating to another fungicide with a 
different mode of action.
*8 fl oz product/A contains 0.10 lb azoxystrobin/A and 0.07 lb difenoconazole/A. 
*14 fl oz product/A contains 0.18 lb azoxystrobin/A and 0.11 lb difenoconazole/A._________________
Application: For best results, sufficient water volume must be used to provide thorough coverage. 
Quadris Top Fungicide can be applied by ground, chemigation, or aerial application. Use a minimum 
of 15 gal/A of water for ground applications. For chemigation, apply in 0.1-0.25 inches/A of water. 
Chemigation with excessive water may lead to a decrease in efficacy.___________________________
Specific Use Restrictions:
Maximum Single Application Rate: Do not exceed the maximum rate listed in the table.
Minimum Application Interval: 14 days
Do not apply more than 4 applications per year at the highest rate.
Do not apply more than 56 fl oz/A/year of Quadris Top Fungicide (0.73 lb azoxystrobin and 
0.46 lb difenoconazole).
Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
Do not apply more than 1.5 lb ai/A/year of azoxystrobin-containing products.
Do not apply within 14 days of harvest (14-day PHI).
Rust
(Uromyces ciceris-
arietini)
Ascochyta Blight 
(A. rabiei)
Use Rate 
fl oz 
product/A
8-14*
Crop
Chickpea 
(garbanzo 
bean)
Target Diseases 
Alternaria Blight 
{A. alternate)

10-15.4*
Including all 
cultivars and/or 
hybrids of these
Alternaria Leaf and 
Fruit Spot 
(Alternaria citri)
Greasy Spot Rind 
Blotch
Black Spot 
{Guignardia 
citricarpa)
See complete list 
of citrus fruit crops 
below.
The addition of a spreading/penetrating type 
adjuvant such as a non-ionic based
surfactant or crop oil concentrate or blend is 
advised.
[Optional language if label has a rate range". 
If disease pressure is high, use the highest 
rate.]
[Optional language if label has a rate range". 
If disease pressure is high, use the highest 
rate.]
Make no more than 2 sequential applications 
before alternating to another fungicide with a 
non-Qol (Group 11) different mode of action. 
Do not make more than 4 applications of 
Quadris Top Fungicide or other Group 11 
fungicides per year.______________________
Quadris Top Fungicide applications must 
begin prior to disease development and 
continue throughout the year on 7- to 21-day 
intervals following the resistance 
management guidelines. Applications may 
be made by ground or air. An adjuvant may 
be added at specified rates. A horticultural 
spray oil needs to be used to improve 
control of greasy spot.
_____________Use Directions____________
Quadris Top Fungicide applications must 
begin prior to disease development and 
continue throughout the year on 7- to 21-day 
intervals following the resistance 
management guidelines. Applications may 
be made by ground or air. An adjuvant may 
be added at specified rates. A horticultural 
spray oil needs to be used to improve 
control of greasy spot.
[Optional language if label has a single rate 
and interval range: If disease pressure is 
high, use the shortest interval.]
[Optional language if label has a rate range 
and interval range". If disease pressure is 
high, use the shortest interval and highest 
rate.]
Grapefruit
Lemon 
Lime
Orange (Sour and
Sweet)
Tangerine
Anthracnose
{Colletotrichum 
spp.)
Quadris Top Fungicide 
Page 31
Target Diseases
Greasy Spot
(Mycosphaerella 
citri)
______Crop______
Citrus Fruit 
Crop Group 10-10
Use Rate 
fl oz 
product/A
10-15.4*

Phomopsis Stem-
End Rot
{Phomopsis citrii)
Make no more than 2 sequential applications 
before alternating to another fungicide with a 
non-Qol (Group 11) different mode of action.
Melanose
(Diaporthe citri)
Post-Bloom Fruit
Drop (PFD) 
(Colletotrichum 
acutatum) The addition of a spreading/penetrating type 
adjuvant such as a non-ionic based 
surfactant or crop oil concentrate or blend is 
advised.
[Optional language if label has a single rate 
and interval range: If disease pressure is 
high, use the shortest interval.]
[Optional language if label has a rate range 
and interval range: If disease pressure is 
high, use the shortest interval and highest 
rate.]
Scab
____________________(Elsinoe fawcettii)
*10 fl oz product/A contains 0.13 lb azoxystrobin/A and 0.08 lb difenoconazole/A. 
*15.4 fl oz product/A contains 0.20 lb azoxystrobin/A and 0.13 lb difenoconazole/A.________________
Application: For best results, sufficient water volume must be used to provide thorough coverage.
Quadris Top Fungicide can be applied by ground or aerial application. Use a minimum of 15 gal/A of 
water for ground applications. For aerial applications, use a minimum of 10 gal/A of water.__________
Complete List of Citrus Fruit Crops: Australian desert lime; Australian finger lime; Australian round 
lime; Brown River finger lime; Calamondin; Citron; Citrus hybrids {Citrus spp., Eremocitrus spp., 
Fortunella spp.. Microcitrus spp., and Poncirus spp).; Grapefruit; Japanese summer grapefruit; 
Kumquat; Lemon; Lime; Mediterranean mandarin; Mount White lime; New Guinea wild lime; Orange, 
sour; Orange, sweet; Pummelo; Russell River lime; Satsuma mandarin; Sweet lime; Tachibana 
orange; Tahiti lime; Tangelo; Tangerine (Mandarin); Tangor; Trifoliate orange; Uniq fruit; cultivars, 
varieties and/or hybrids of these.____________________________________________________________
Specific Use Restrictions:
1) Maximum Single Application Rate: Do not exceed the maximum rate listed in the table.
2) Minimum Application Interval: 7 days
3) Do not apply more than 3 applications per year at the highest rate.
4) Do not use Quadris Top Fungicide in citrus plant propagation nurseries.
5) Do not apply more than 61.5 fl oz/A/year of Quadris Top Fungicide (0.80 lb azoxystrobin and
0.50 lb difenoconazole).
6) Do not apply more than 0.5 lb ai/A/year of difenoconazole-containing products.
7) Do not apply more than 1.5 lb ai/A/year of azoxystrobin-containing products.
8) Do not make more than 4 applications of Quadris Top Fungicide or other Group 11 fungicides 
per year.
9) May be applied the day of harvest (0-day PHI).
(Mycosphaerella
citri)
Quadris Top Fungicide
Page 32

Make no more than two sequential applications 
before alternating to a fungicide with a different 
mode of action.
For foliar disease control, the first application 
needs to be targeted approximately at pin-head 
square to first bloom or when conditions are 
conducive for disease development. For best 
control of target spot, adjust the GPA to ensure 
coverage of upper and lower leaves.
Subsequent applications may be made on a 14- 
21 day interval.
______________Use Directions_____________
For best activity, apply Quadris Top Fungicide 
prior to or early in the disease development. An 
adjuvant may be added at specified rates.
Quadris Top Fungicide
Page 33
Crop
Cotton 
Subgroup
20C
Target Diseases
Alternaria leaf spot
(Alternaria spp)
Anthracnose
{Glomerella gossypn)
Aerolate mildew
{Ramularia gossypii)
Ascochyta blight
{A. gossypii)
Boll rots
{Ascochyta gossypii,
Alternaria spp.,
Diplodia spp., Phoma
spp.)
Cotton rust
(Puccinia
schedonnardi)
Diplodia boll rot
{Diplodia spp.)
Hardlock
{Fusarium
verticillioides)
Leafspots and blights
{Alternaria spp.,
Ascochyta gossypii,
Cercospora spp.,
Stemphyllium spp.)
Southwesterrn cotton
rust
{Puccina cacabata,
Puccinia spp.)
Stemphyllium leaf spot
{Stemphyllium spp.)
Target spot
(Cornyespora
cassiicola)_________
*8 fl oz product/A contains 0.10 lb azoxystrobin/A and 0.07 lb difenoconazole/A.
*11.6 fl oz product/A contains 0.095 lb difenoconazole/A and 0.15 lb azoxystrobin/A._____________
Application: For best results, sufficient water volume must be used to provide thorough coverage. 
Quadris Top Fungicide can be applied by ground, chemigation, or aerial application. For aerial 
applications, use a minimum of 5 gal/A of water. For chemigation, apply in 0.1-0.25 inches/A of 
water. Chemigation with excessive water may lead to a decrease in efficacy. Applicators must use 
care in making applications near non-target aquatic habitats.
Use Rate 
fl oz 
product/A
8-11.6*

1)
2)
3)
4)
5)
6)
7)
Make no more than two sequential 
applications before alternating to a 
fungicide with a different mode of action.
[Not for use in 
California.]
____________Use Directions__________
For best activity, apply Quadris Top
Fungicide prior to or early in the disease 
development. An adjuvant may be added 
at specified rates. Apply on a 7-14 day 
interval.
Specific Use Restrictions:
Maximum Single Application Rate: Do not exceed the maximum rate listed in the table.
Minimum Application Interval: 14 days
Do not apply more than 3 applications per year at the highest rate.
Do not apply more than 34.8 fl oz/A/year of Quadris Top Fungicide (0.45 lb azoxystrobin and 0.29 
lb difenoconazole).
Do not apply more than 0.45 lb ai/A/year of azoxystrobin-containing products.
Do not apply more than 0.34 lb ai/A/year of difenoconazole-containing products.
Do not apply Quadris Top Fungicide within 45 days of harvest (45-day PHI).
Quadris Top Fungicide 
Page 34
Target Diseases
Bitter rot
{Colletotrichum
gloeosporioides)
Blotch rot
{Physalospora
vaccinia)
Cottonball
{Moniiinia
oxycocci)
Fruit Rots
{Physalospora
vaccinia)
{Glomerella
ci ng uI ata)
{Coleophoma
empetri)
Leaf rust
{Pucciniastrum
vaccinii)
Lophodermium
Twig Blight
{Lophodermium
spp.)
Ripe rot
{Coleophoma
empetri)_______
*10 fl oz product/A contains 0.13 lb azoxystrobin/A and 0.08 lb difenoconazole/A. 
*14 fl oz product/A contains 0.18 lb azoxystrobin/A and 0.11 lb difenoconazole/A.____________
Application: For best results, sufficient water volume must be used to provide thorough 
coverage. Quadris Top Fungicide can be applied by ground, chemigation, or aerial application. 
For aerial applications, apply in a minimum of 5 gal/A of water. For chemigation, apply in 0.1 -
0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy.
Applicators must use care in making applications near non-target aquatic habitats.
_____ Crop
Cranberry
Use Rate 
fl oz 
product/A
10-14*

Anthracnose 
{Colletotrichum 
orbiculare)
Gummy Stem Blight 
{Didymella bryoniae)
Downy Mildew 
{Pseudoperonospora
cubensis)
Myrothecium Canker
(M. roridum)
Phoma Blight 
{P. exigua)
Cantaloupe 
Cucumber 
Honeydew 
Muskmelon 
Watermelon
Pumpkin
Squash 
Zucchini
Belly Rot
{Rhizoctonia solani)
The addition of a spreading/penetrating type 
adjuvant such as a non-ionic based surfactant 
or crop oil concentrate or blend is advised.
For belly rot control, the first application needs 
to be made at the 1- to 3-leaf crop stage with a 
second application just prior to vine tip or 10- 
14 days later, whichever occurs first.
Alternaria Leaf Spot 
{A. al tern ata}
[Optional language if label has a rate range : If 
disease pressure is high, use the highest rate.]
Specific Use Restrictions:
1) Maximum Single Application Rate: Do not exceed the maximum rate listed in the table.
2) Minimum Application Interval: 7 days
3) Do not apply more than 3 applications per year at the highest rate.
4) Do not apply more than 42 fl oz/A/year of Quadris Top Fungicide (0.55 lb azoxystrobin and 
0.34 lb difenoconazole).
5) Do not apply more than 0.34 lb ai/A/year of difenoconazole-containing products.
6) Do not apply more than 1.5 lb ai/A/year of azoxystrobin-containing products.
7) Do not allow release of irrigation or flood water to non-target aquatic habitat for at least 14 
days after the last application.
8) Do not apply when weather conditions favor drift from treated areas to non-target aquatic 
habitat.
9) Do not treat fields used for aquaculture of fish or crustacean.
10) Do not drain water from treated fields into ponds used for aquaculture offish or crustacean.
11) Do not use water drained from treated field to irrigate other crops.
12) Do not apply to flooded crop.
13) Do not apply Quadris Top Fungicide within 30 days of harvest (30-day PHI).
______________Use Directions_____________
Begin applications prior to disease onset when 
conditions are conducive for disease. Apply 
Quadris Top Fungicide on a 7- to 14-day 
schedule, making no more than 1 application 
of a Qol containing fungicide before alternating 
to another fungicide with a different mode of 
action.
[Optional language if label has a single rate 
and interval range: If disease pressure is high, 
use the shortest interval.]
[Optional language if label has a rate range 
and interval range: If disease pressure is high, 
use the shortest interval and highest rate.]
Including 
cultivars 
and/or 
hybrids of 
these
See 
additional 
cucurbit 
crops below.
Cercospora Leaf Spot 
(C. citrulline}
Use Rate 
fl oz 
product/A
10-14*
Quadris Top Fungicide 
Page 35
Crop 
Cucurbit 
Vegetables 
Crop Group 
9
Target Diseases
Alternaria Leaf Blight 
(A. cucumerina}

Plectosporium Blight 
{P. tabacinum)
Powdery Mildew 
{Sphaerotheca 
fuliginea, Erysiphe 
cichoracearum)
Phyllosticta Leaf Spot 
{P. cucurbitacearum)
Septoria Leaf Blight
_______________(S. cucurbitacearum) |____________________________________________________
*10 fl oz product/A contains 0.13 lb azoxystrobin/A and 0.08 lb difenoconazole/A.
*12 fl oz product/A contains 0.16 lb azoxystrobin/A and 0.10 lb difenoconazole/A
*14 fl oz product/A contains 0.18 lb azoxystrobin/A and 0.11 lb difenoconazole/A.__________________
Application: For best results, sufficient water volume must be used to provide thorough coverage. 
Quadris Top Fungicide can be applied by ground, chemigation, or aerial application. Use a minimum 
of 15 gal/A of water for ground applications (20 for gummy stem blight). For chemigation, apply in
0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy. 
Complete List of Cucurbit Vegetables: Chayote (fruit); Chinese waxgourd (Chinese preserving 
melon); citron melon; cucumber; gherkin; gourd, edible (includes hyotan, cucuzza, hechima, Chinese 
okra); Momordica spp. (includes balsam apple, balsam pear, bittermelon, Chinese cucumber); 
muskmelon (includes cantaloupe); pumpkin; squash, summer; squash, winter (includes butternut 
squash, caiabaza, hubbard squash, acorn squash, spaghetti squash); watermelon________________
Specific Use Restrictions:
1) Maximum Single Application Rate: Do not exceed the maximum rate listed in the table.
2) Minimum Application Interval: 7 days
3) Do not apply more than 4 applications per year at the highest rate.
4) Do not apply more than 56 fl oz/A/year of Quadris Top Fungicide (0.73 lb azoxystrobin and 0.46 lb 
difenoconazole).
5) Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
6) Do not apply more than 1.5 lb ai/A/year of azoxystrobin-containing products.
7) Do not apply within 1 day of harvest (1-day PHI).
Quadris Top Fungicide 
Page 36

1)
2)
3)
4)
5)
6)
Zi
The addition of a spreading/penetrating type 
adjuvant such as a non-ionic based surfactant or 
crop oil concentrate or blend is advised.
[Optional language if label has a rate range: If 
disease pressure is high, use the highest rate.]
______________Use Directions____________
Begin applications prior to disease onset when 
conditions are conducive for disease. Apply 
Quadris Top Fungicide on a 14- to 21-day 
schedule making no more than 2 sequential 
applications before alternating to another 
fungicide with a non-Qol (Group 11) different 
mode of action.
[Optional language if label has a single rate and 
interval range: If disease pressure is high, use 
the shortest interval.]
[Optional language if label has a rate range and 
interval range: If disease pressure is high, use
__________________________________I___________the shortest interval and highest rate.]__________
*12 fl oz product/A contains 0.16 lb azoxystrobin/A and 0.10 lb difenoconazole/A.
*14 fl oz product/A contains 0.18 lb azoxystrobin/A and 0.11 lb difenoconazole/A._________________
Application: For best results, sufficient water volume must be used to provide thorough coverage.
Quadris Top Fungicide can be applied by ground or aerial application. Use a minimum of 15 gal/A of 
water for ground applications. For aerial applications, use a minimum of 10 gal/A of water._________
Specific Use Restrictions:
Maximum Single Application Rate: Do not exceed the maximum rate listed in the table.
Minimum Application Interval: 14 days
Do not apply more than 4 applications per year at the highest rate.
Do not apply more than 56 fl oz/A/year of Quadris Top Fungicide (0.73 lb azoxystrobin and
0.46 lb difenoconazole).
Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
Do not apply more than 1.2 lb ai/A/year of azoxystrobin-containing products. 
Do not apply within 45 days of harvest (45-day PHI).
Use Rate 
fl oz 
product/A
12-14*
Quadris Top Fungicide 
Page 37
Target Diseases 
Eastern Filbert Blight 
{Anisogramma 
anomala)
Crop
Filberts 
(Hazelnuts)

See complete list of 
peppers and other 
fruiting vegetables 
below.
Gray Leaf Spot 
(Stemphyllium 
solani)
Powdery Mildew
(Oidiopsis 
sicula)
The addition of a spreading/penetrating 
type adjuvant such as a non-ionic based 
surfactant or crop oil concentrate or blend is 
advised.
____________Use Directions__________
Begin applications prior to disease 
development and continue throughout the 
year on a 7- to 10-day interval. Make no 
more than 2 consecutive applications 
before switching to another effective 
fungicide with a different mode of action.
[Optional language if label has a single rate 
and interval range: If disease pressure is 
high, use the shortest interval.]
[Optional language if label has a rate range : 
If disease pressure is high, use the highest 
rate.]
Cercospora Leaf
Spot
(C. capsid)
[Optional language if label has a rate range 
and interval range: If disease pressure is 
high, use the shortest interval and highest 
rate.]
The addition of a spreading/penetrating
_________________________________________________type adjuvant may enhance efficacy._______
*8 fl oz product/A contains 0.10 lb azoxystrobin/A and 0.07 lb difenoconazole/A.
*14 fl oz product/A contains 0.18 lb azoxystrobin/A and 0.11 lb difenoconazole/A.__________________
Application: For best results, sufficient water volume must be used to provide thorough coverage.
Quadris Top Fungicide can be applied by ground or aerial application. Use a minimum of 15 gal/A of 
water for ground applications. For aerial applications, use a minimum of 10 gal/A of water._________
Complete List of Peppers and Other Fruiting Vegetables: African eggplant; Bell pepper;
Eggplant; Martynia; Non-bell pepper; Okra; Pea eggplant; Pepino; Roselle; Scarlet eggplant; 
cultivars, varieties; and/or hybrids of these.___________________________________________________
Specific Use Restrictions:
1) Maximum Single Application Rate: Do not exceed the maximum rate listed in the table.
2) Minimum Application Interval: 7 days
3) Do not apply more than 3 applications per year at the highest rate.
4) Do not apply more than 55.3 fl oz/A/year of Quadris Top Fungicide (0.72 lb azoxystrobin and 0.45 
lb difenoconazole).
5) Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
6) Do not apply more than 1.0 lb ai/A/year of azoxystrobin-containing products.
7) May be applied the day of harvest (0-day PHI).
Including all cultivars 
and/or hybrids of 
these
See Tomatoes 
section for specific 
directions.
Peppers
Bell Pepper
Non-Bell Pepper 
Sweet Non-Bell 
Eggplant
Quadris Top Fungicide 
Page 38
Target Diseases
Anthracnose
(Colletotrichum
spp.)
Use Rate 
fl oz 
product/A
8-14*
_______ Crop______ 
Fruiting Vegetables 
Crop Group 8-10 A 
and B

1)
2)
3)
4)
5)
6)
7)
Powdery Mildew 
(Erysiphe spp.)
____________Use Directions___________
Begin applications prior to disease onset 
when conditions are conducive for 
disease. Apply Quadris Top Fungicide on 
a 7- to 14-day schedule making no more 
than 2 sequential applications before 
alternating to another fungicide with a 
different mode of action.________________
*10 fl oz product/A contains 0.13 lb azoxystrobin/A and 0.08 lb difenoconazole/A. 
*14 fl oz product/A contains 0.18 lb azoxystrobin/A and 0.11 lb difenoconazole/A._________________
Application: For best results, sufficient water volume must be used to provide thorough coverage. 
Quadris Top Fungicide can be applied by ground, chemigation, or aerial application. Use a minimum 
of 15 gal/A for ground applications. For aerial applications, use a minimum of 10 gal/A of water. For 
chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with excessive water may lead to a 
decrease in efficacy.______________________________________________________________________
Specific Use Restrictions:
Maximum Single Application Rate: Do not exceed the maximum rate listed in the table.
Minimum Application Interval: 7 days
Do not apply more than 4 applications per year at the highest rate.
Do not apply more than 56 fl oz/A/year of Quadris Top Fungicide (0.73 lb azoxystrobin and 0.46 
lb difenoconazole).
Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
Do not apply more than 2.0 lb ai/A/year of azoxystrobin-containing products.
Quadris Top Fungicide may be applied the day of harvest (0-day PHI).
Quadris Top Fungicide 
Page 39
______ Crop 
Ginseng
Target Diseases 
Alternaria Blight 
(A.panax)
Use Rate 
fl oz 
product/A
10-14*

Angular Leaf Spot 
{Mycosphearella 
angulata}
Septoria Leaf Spot 
(S. ampelina}
Black Rot
{Guignarda bidwellii)
Downy Mildew 
{Plasmopara
viticola}
Powdery Mildew 
{Uncinula necator)
QuadrisTop Fungicide
Page 40
Anthracnose
{Elsinoe ampelina)
Rotbrenner
{Pseudopezicula 
tracheiphila)
PRECAUTION: Avoid rates of 
methylated or ethylated vegetable 
oil/organosilicone adjuvants over
0.125% with Quadris Top Fungicide as 
grape leaf injury may occur. 
PRECAUTION: On V. labrusca, V. 
labrusca hybrids and other non- 
viniferea hybrids where sensitivity is 
not known, the use of Quadris Top 
Fungicide by itself or in tank
For black rot, begin when shoot length 
is 1-3 inches and continue on a 10-day 
interval.
Suppression only: 
Botrytis Bunch Rot 
(S. cinerea)
For all other diseases, begin 
applications prior to disease onset 
when conditions are conducive for 
disease. Apply Quadris Top Fungicide 
on a 10- to 14-day schedule, making no 
more than 2 sequential applications 
before alternating to another fungicide 
with a non-Qol (Group 11) mode of 
action.
For Phomopsis diseases, apply at bud 
break before shoots are 0.5 inches in 
length, and then again when shoots are 
5-6 inches in length.
__________Use Directions________
For powdery mildew, begin at bud 
break and apply on a 10- to 21-day 
interval, making no more than 2 
sequential applications before 
alternating to another fungicide with a 
non-Qol (Group 11) mode of action.
(Fruit, small, 
vine 
climbing, 
except fuzzy 
kiwifruit- 
subgroup 
13-07F)
See 
additional 
crops in this 
subgroup 
below.
Leaf Blight
{Pseudocercospora
vitis)
Use Rate 
fl oz 
product/A
10-14*
[Optional language if label has a rate 
range'. If disease pressure is high, use 
the highest rate.]
[Optional language if label has a single 
rate and interval range: If disease 
pressure is high, use the shortest 
interval.]
[Optional language if label has a rate 
range and interval range'. If disease 
pressure is high, use the shortest 
interval and highest rate.]
Crop
Grapes 
(except 
Concord, 
Concord 
Seedless, 
and 
Thomcord. 
See 
Precaution 
under Use 
Directions.)
Phomopsis Cane and
Leaf Spot
(P. viticola)
Target Diseases
Al tern a ria Rot 
(A. alternate)

ATTENTION
1)
2)
3)
4)
5)
6)
7)
QuadrisTop Fungicide
Page 41
mixtures with materials that may 
increase uptake (adjuvants, foliar 
fertilizers) may result in leaf burning 
or other phytotoxic effects.
Quadris Top Fungicide is extremely
phytotoxic to certain apple varieties. 
Refer to caution in Use Precautions 
___________________________________I___________and Restrictions section of label. 
*10 fl oz product/A contains 0.13 lb azoxystrobin/A and 0.08 lb difenoconazole/A. 
*12 fl oz product/A contains 0.16 lb azoxystrobin/A and 0.10 lb difenoconazole/A 
*14 fl oz product/A contains 0.18 lb azoxystrobin/A and 0.11 lb difenoconazole/A.___________
Complete list of small fruit vine climbing, except fuzzy kiwifruit, subgroup 13-07F: 
Amur river grape; gooseberry; grape; kiwifruit, hardy; maypop: schisandra berry; cultivars, 
varieties, and/or hybrids of these_____________________________________________________
Application: For best results, sufficient water volume must be used to provide thorough 
coverage. Quadris Top Fungicide can be applied by ground or aerial application. Use a 
minimum of 15 gal/A of water for ground applications. For aerial applications, use a minimum 
of 10 gal/A of water.________________________________________________________________
Specific Use Restrictions:
Maximum Single Application Rate: Do not exceed the maximum rate listed in the 
table.
Minimum Application Interval: 10 days
Do not apply more than 4 applications per year at the highest rate.
Do not apply more than 56 fl oz/A/year of Quadris Top Fungicide (0.73 lb azoxystrobin 
and 0.46 lb difenoconazole).
Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products. 
Do not apply more than 1.5 lb ai/A/year of azoxystrobin-containing products. 
Do not apply within 14 days of harvest (14-day PHI).

1)
2)
3)
4)
5)
6)
Zi
Make no more than two sequential 
applications before alternating to a 
fungicide with a different mode of action.
Anthracnose
{Colletotrichum 
gloeosporioides)
____________Use Directions__________
For best activity, apply Quadris Top
Fungicide prior to or early in the disease 
development. An adjuvant may be added 
at specified rates. Apply on 10-14 day 
interval.
Quadris Top Fungicide 
Page 42
Suppression
Rust
__________________(Puccinia psidii)
*10 fl oz product/A contains 0.13 lb azoxystrobin/A and 0.08 lb difenoconazole/A. 
*14 fl oz product/A contains 0.18 lb azoxystrobin/A and 0.11 lb difenoconazole/A.____________
Application: For best results, sufficient water volume must be used to provide thorough 
coverage. Quadris Top Fungicide can be applied by ground, chemigation, or aerial application. 
For aerial applications, apply in a minimum of 10 gal/A of water. For chemigation, apply in 0.1 - 
0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy. 
Applicators must use care in making applications near non-target aquatic habitats.___________
Specific Use Restrictions:
Maximum Single Application Rate: Do not exceed the maximum rate listed in the table. 
Minimum Application Interval: 10 days
Do not apply more than 4 applications per year at the highest rate.
Do not apply more than 56 fl oz/A/year of Quadris Top Fungicide (0.73 lb azoxystrobin and 
0.46 lb difenoconazole).
Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
Do not apply more than 1.5 lb ai/A/year of azoxystrobin-containing products. 
Quadris Top Fungicide may be applied the day of harvest (0-day PHI).
_____ Crop 
Guava
Target Diseases
Alternaria Fruit 
Rot
Use Rate 
fl oz 
product/A
10-14*

1)
2)
3)
4)
5)
6)
7)
Powdery Mildew 
{Oidium spp.)
Make no more than two sequential 
applications before alternating to a 
fungicide with a different mode of action.
____________Use Directions__________
For best activity, apply Quadris Top
Fungicide prior to or early in the disease 
development. An adjuvant may be added 
at specified rates. Apply on 10-14 day 
interval.
Alternaria fruit 
spot 
(A. alternata)
Quadris Top Fungicide 
Page 43
_____ Crop 
Papaya
Target Diseases 
Blossom blight 
and fruit rot 
{Colletotrichum 
gloeosporioides)
Use Rate 
fl oz 
product/A
10-14*
Brown Spot
{Corynespora
__________________cassicola)________________________________________________________
*10 fl oz product/A contains 0.13 lb azoxystrobin/A and 0.08 lb difenoconazole/A.
*14 fl oz product/A contains 0.18 lb azoxystrobin/A and 0.11 lb difenoconazole/A.____________
Application: For best results, sufficient water volume must be used to provide thorough 
coverage. Quadris Top Fungicide can be applied by ground, chemigation, or aerial application. 
For aerial applications apply in a minimum of 10 gal/A of water. For chemigation, apply in 0.1- 
0.25 inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy. 
Applicators must use care in making applications near non-target aquatic habitats.___________
Specific Use Restrictions:
Maximum Single Application Rate: Do not exceed the maximum rate listed in the table. 
Minimum Application Interval: 10 days
Do not apply more than 4 applications per year at the highest rate.
Do not apply more than 56 fl QzJKIyear of Quadris Top Fungicide (0.73 lb azoxystrobin and 
0.46 lb difenoconazole).
Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
Do not apply more than 1.5 lb ai/A/year of azoxystrobin-containing products. 
Quadris Top Fungicide may be applied the day of harvest (0-day PHI).

1)
2)
3)
4)
5)
6)
7)
Vein Spot
{Gnomomia 
nerviseda)
Liver Spot
{Gnomonia caryae 
pv pecanae)
Powdery Mildew 
{Microsphaera 
penicillata)
QuadrisTop Fungicide
Page 44
The addition of a spreading/penetrating type 
adjuvant such as a non-ionic based surfactant or 
crop oil concentrate or blend is specified.
[Optional language if label has a rate range: If 
disease pressure is high, use the highest rate.]
Crop 
Pecans
______________Use Directions____________
Begin applications prior to disease onset when 
conditions are conducive for disease. Apply 
Quadris Top Fungicide on a 14- to 21-day 
schedule, making no more than 2 sequential 
applications before alternating to another 
fungicide with a non-Qol (Group 11) mode of 
action.
[Optional language if label has a single rate and 
interval range: If disease pressure is high, use 
the shortest interval.]
[Optional language if label has a rate range and 
interval range: If disease pressure is high, use 
the shortest interval and highest rate.]
Zonate Leaf Spot
{Grovesinia
_______________pyramidalis)
*8 fl oz product/A contains 0.10 lb azoxystrobin/A and 0.07 lb difenoconazole/A. 
*14 fl oz product/A contains 0.18 lb azoxystrobin/A and 0.11 lb difenoconazole/A._________________
Application: For best results, sufficient water volume must be used to provide thorough coverage.
Quadris Top Fungicide can be applied by ground or aerial application. Use a minimum of 15 gal/A of 
water for ground applications. For aerial applications, use a minimum of 10 gal/A of water._________
Specific Use Restrictions:
Maximum Single Application Rate: Do not exceed the maximum rate listed in the table.
Minimum Application Interval: 14 days
Do not apply more than 4 applications per year at the highest rate.
Do not apply more than 56 fl oz/A/year of Quadris Top Fungicide (0.73 lb azoxystrobin and
0.46 lb difenoconazole).
Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
Do not apply more than 1.2 lb ai/A/year of azoxystrobin-containing products.
Do not apply within 45 days of harvest (45-day PHI).
Pecan Scab 
{Cladosporium 
caryigenum)
Target Diseases
Downy Spot 
{Mycosphaerella 
caryigena}
Use Rate 
fl oz 
product/A
8-14*

1)
2)
3)
4)
5)
6)
7)
Septoria Leaf Spot 
(S. pistaciarum)
The addition of a spreading/penetrating type 
adjuvant such as a non-ionic based surfactant or 
crop oil concentrate or blend is specified.
[Optional language if label has a rate range: If 
disease pressure is high, use the highest rate.]
______________Use Directions____________
Begin applications prior to disease onset when 
conditions are conducive for disease. Apply 
Quadris Top Fungicide on a 14- to 21-day 
schedule, making no more than 2 sequential 
applications before alternating to another 
fungicide with a non-Qol (Group 11) mode of 
action.
[Optional language if label has a single rate and 
interval range: If disease pressure is high, use 
the shortest interval.]
[Optional language if label has a rate range and 
interval range: If disease pressure is high, use
 I the shortest interval and highest rate.]__________ 
*10 fl oz product/A contains 0.13 lb_azoxystrobin/A and 0.08 lb difenoconazole/A.
*12 fl oz product/A contains 0.16 lb azoxystrobin/A and 0.10 lb difenoconazole/A
*14 fl oz product/A contains 0.18 lb azoxystrobin/A and 0.11 lb difenoconazole/A._________________
Application: For best results, sufficient water volume must be used to provide thorough coverage.
Quadris Top Fungicide can be applied by ground or aerial application. Use a minimum of 15 gal/A of 
water for ground applications. For aerial applications, use a minimum of 10 gal/A of water._________
Specific Use Restrictions:
Maximum Single Application Rate: Do not exceed the maximum rate listed in the table.
Minimum Application Interval: 14 days
Do not apply more than 4 applications per year at the highest rate.
Do not apply more than 56 fl oz/A/year of Quadris Top Fungicide (0.73 lb azoxystrobin and
0.46 lb difenoconazole).
Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
Do not apply more than 1.5 lb ai/A/year of azoxystrobin-containing products. 
Do not apply within 14 days of harvest (14-day PHI).
Quadris Top Fungicide 
Page 45
Panicle and Shoot 
Blight
{Botryosphaeria 
dothidea)
Crop 
Pistachios
Target Diseases 
Alternaria Late Blight 
{Alternaria spp.)
Use Rate 
fl oz 
product/A
10-14*

1)
2)
3)
4)
5)
6)
7)
Brown Spot 
(Alternaria 
alternata)
Early Blight 
(Alternaria solani)
Powdery Mildew 
(Erysiphe
cichoracearum)
QuadrisTop Fungicide
Page 46
Septoria Leaf Spot 
(S. lycopersici)
The addition of a spreading/penetrating type 
adjuvant such as a non-ionic based surfactant or 
crop oil concentrate or blend is advised.
[Optional language if label has a rate range: If 
disease pressure is high, use the highest rate.]
______________Use Directions______________
Begin applications prior to disease development 
and continue throughout the year on a 7- to 14- 
day interval. Make no more than 2 consecutive 
applications before switching to another 
effective fungicide with a different mode of 
action.
[Optional language if label has a rate range and 
interval range: if disease pressure is high, use 
the shortest interval and highest rate.]
[Optional language if label has a single rate and 
interval range: If disease pressure is high, use 
the shortest interval.]
Crop 
Potatoes
The addition of a spreading/penetrating type
__________________________________I___________ adjuvant may enhance efficacy._____________
*8 fl oz product/A contains 0.10 lb azoxystrobin/A and 0.07 lb difenoconazole/A.
*14 fl oz product/A contains 0.18 lb azoxystrobin/A and 0.11 lb difenoconazole/A.________________
Application: For best results, use sufficient water volume to provide thorough coverage. Quadris
Top Fungicide may be applied by ground, chemigation, or aerial application._____________________
Specific Use Restrictions:
Maximum Single Application Rate: Do not exceed the maximum rate listed in the table.
Minimum Application Interval: 7 days
Do not apply more than 3 applications per year at the highest rate.
Do not apply more than 55.3 fl oz/A/year of Quadris Top Fungicide (0.72 lb azoxystrobin and 
0.45 lb difenoconazole).
Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
Do not apply more than 2.0 lb ai/A/year of azoxystrobin-containing products
Do not apply within 14 days of harvest (14-day PHI).
Use Rate 
fl oz 
product/A
8-14*
Target Diseases
Black Dot 
(Colletotrichum 
coccodes)

15
For hybrids/varieties with partial resistance to 
sheath blight, the lower rate of 10 fl oz/A may 
be used.
Quadris Top Fungicide may be applied to a 
ratooned crop for control of Sheath blight.
Crop
Rice
Suppression of: 
False smut
{Ustilaginoidea virens) 
Panicle Blast
{Pyricularia grises)
______________Use Directions_____________
Apply 11.25-15 fl oz/A when disease is less 
than 4 inches above water line usually between 
panicle differentiation (PD) +5 days to PD +10 
days or at initial sign of disease. Under heavy 
disease pressure and conditions favorable for 
disease development, use 15 fl oz/A rate and a 
second application may be applied. Minimum 
re-treatment interval is 14 days.
Quadris Top Fungicide must be applied as a 
preventative treatment for blast control and 
applied prior to favorable conditions for blast 
development. For panicle blast, an application 
needs to be applied at mid-boot to boot-split but 
prior to full head emergence. A second 
application needs to be applied when panicles 
are approximately 60-90% emerged from the 
boot (Minimum 14 days later).________________
*10 fl oz product/A contains 0.13 lb azoxystrobin/A and 0.08 lb difenoconazole/A. 
*15 fl oz product/A contains 0.196 lb azoxystrobin/A and 0.123 lb difenoconazole/A._______________
Application: For best results, sufficient water volume must be used to provide thorough coverage. 
Quadris Top Fungicide can be applied by ground or aerial application. For aerial applications, use a 
minimum of 5 gal/A of water. Applicators must use care in making applications near non-target 
aquatic habitats.
Quadris Top Fungicide 
Page 47
Target Diseases
Sheath Blight 
{Rhizoctonia solani)
Aggregate Sheath Spot 
{Rhizoctonia oryzae- 
sativae)
Black Sheath Rot 
{Gaeumannomyces
graminis var.
graminis)
Sheath Spot 
{Rhizoctonia oryzae) 
Stem Rot 
(Sclerotium oryzae)
Brown Leaf spot 
{Cochliobolus 
miyabeanus)
Leaf Smut 
{Entyloma oryzae) 
Narrow Brown Leaf 
spot
{Cercospora oryzae) 
Kernel Smut
{Neovossia 
barclayana)
Use Rate 
fl oz 
product/A
10-15*

QuadrisTop Fungicide
Page 48
Specific Use Restrictions:
1) Maximum Single Application Rate: Do not exceed the maximum rate listed in the table.
2) Minimum Application Interval: 14 days
3) Do not apply more than 4 applications per year at the highest rate.
4) Do not treat rice fields used for aquaculture offish or crustacean.
5) Do not apply when weather conditions favor drift from treated areas to non-target aquatic habitat.
6) Do not allow release of irrigation or flood water for at least 14 days after the last application.
7) Do not apply more than 30 fl oz/A/year of Quadris Top Fungicide (0.39 lb azoxystrobin and 0.25 
lb difenoconazole).
8) Do not apply more than 0.7 lb ai/A/year of azoxystrobin-containing products.
9) Do not apply more than 0.244 lb ai/A/year of difenoconazole-containing products.
10) Do not apply Quadris Top Fungicide within 28 days of harvest (28-day PHI).
11) Do not drain water from treated rice fields into ponds used for aquaculture of fish or crustacean.
12) Do not use water drained from treated field to irrigate other crops.

1)
2)
3)
4)
5)
6)
7)
Anthracnose
{Colletotrichum 
truncatum)
Cercospora Blight 
and Leaf Spot 
(C. kikuchii}
Frogeye Leaf Spot 
{Cercospora sojina)
Pod and Stem Blight 
{Diaporthe
phaseolorum}
Alternaria Leaf Spot 
{Alternaria spp.)
Brown Spot
{Septoria glycines)
Powdery Mildew 
{Microsphaera 
diffusa)
The addition of a spreading/penetrating type 
adjuvant such as a non-ionic based surfactant or 
crop oil concentrate or blend is advised.
[Optional language if label has a rate range: If 
disease pressure is high, use the highest rate.]
______________Use Directions____________
Begin applications prior to disease onset when 
conditions are conducive for disease. Apply 
Quadris Top Fungicide on a 7- to 10-day 
schedule making no more than 2 sequential 
applications before alternating to another 
fungicide with a different mode of action.
[Optional language if label has a single rate and 
interval range: If disease pressure is high, use 
the shortest interval.]
[Optional language if label has a rate range and 
interval range: If disease pressure is high, use 
the shortest interval and highest rate.]
Rust
_______________{Phakopsora spp.) |_____________________________________________________
*8 fl oz product/A contains 0.10 lb azoxystrobin/A and 0.07 lb difenoconazole/A.
*14 fl oz product/A contains 0.18 lb azoxystrobin/A and 0.11 lb difenoconazole/A.________________
Application: For best results, sufficient water volume must be used to provide thorough coverage. 
Quadris Top Fungicide can be applied by ground, chemigation, or aerial application. For aerial 
applications, use a minimum of 2 gal/A of water. For chemigation, apply in 0.1-0.25 inches/A of 
water. Chemigation with excessive water may lead to a decrease in efficacy.____________________
Specific Use Restrictions:
Maximum Single Application Rate: Do not exceed the maximum rate listed in the table.
Minimum Application Interval: 7 days
Do not apply more than 1 application per year at the highest rate.
Do not apply more than 26.5 fl oz/A/year of Quadris Top Fungicide (0.35 lb azoxystrobin and 
0.22 lb difenoconazole).
Do not apply more than 0.22 lb ai/A/year of difenoconazole-containing products.
Do not apply more than 1.5 lb ai/A/year of azoxystrobin-containing products.
Do not feed soybean hay, forage and silage to livestock.
Do not apply within 14 days of harvest (14-day PHI).
Quadris Top Fungicide 
Page 49
Crop 
Soybean
Target Diseases
Aerial Blight
{Rhizoctonia solan!)
Use Rate 
fl oz 
product/A
8-14*

Including all 
cultivars and/or 
hybrids of these
The addition of a spreading/penetrating type 
adjuvant such as a non-ionic based surfactant 
or crop oil concentrate or blend is advised.
For all other diseases, follow the brown rot 
blossom blight schedule. Make additional 
applications on a 10- to 14-day interval from 
the end of petal fall to harvest.
[Optional language if label has a rate range". If 
disease pressure is high, use the highest rate.]
For brown rot on fruit, apply as needed a 
maximum of two sprays during the pre-harvest 
period up to the day of harvest (minimum of a 
7-day retreatment interval). If high inoculum 
and severe disease conditions persist, apply a 
registered fungicide that is non-Group 11 or 
non-Group 9.
[Optional language if label has a single rate 
and interval range: If disease pressure is 
high, use the shortest interval.]
_____________Use Directions________
For brown rot blossom blight, begin 
applications at early bloom and continue 
through petal fall.
QuadrisTop Fungicide
Page 50
_____Crop_____
Stone Fruit,
Crop Group 12- 
12
Apricots 
Cherries, Sweet 
Cherries, Tart 
Nectarines
Peaches 
Plums 
Plumcot 
Prunes
Target Diseases 
Alternaria Spot 
and Fruit Rot 
{A. alternate)
Anthracnose 
{Colletotrichum
spp.)
Brown Rot 
Blossom Blight 
and Fruit Rot 
{Monilinia 
fructicola,
M. laxa)
Leaf Rust 
{Tranzschelia 
discolor) 
Powdery Mildew 
{Sphaerotheca 
pannosa,
Podosphaera 
clandestine)
Scab 
{Cladosporium 
carpophilum)
Shot Hole 
{Wilsonomyces 
carpophilus)
Use Rate 
fl oz 
product/A
8-14*
[Optional language if label has a rate range 
and interval range". If disease pressure is 
high, use the shortest interval and highest 
_____________________________I_________ rate.]_____________________________
*8 fl oz product/A contains 0.10 lb azoxystrobin/A and 0.07 lb difenoconazole/A.
*12 fl oz product/A contains 0.16 lb azoxystrobin/A and 0.10 lb difenoconazole/A
*14 fl oz product/A contains 0.18 lb azoxystrobin/A and 0.11 lb difenoconazole/A._________________
Application: For best results, sufficient water volume must be used to provide thorough coverage. 
Quadris Top Fungicide can be applied by ground or aerial application. Stone fruit diseases are most 
effectively controlled by ground applications. Use a minimum of 15 gal/A of water for ground 
applications. For aerial applications, use a minimum of 10 gal/A of water.________________________
Complete List of Stone Fruit Crops: Apricot; apricot, Japanese; capulin; cherry, black; cherry, 
Nanking; cherry, sweet; cherry, tart; Jujube, Chinese; nectarine; peach; plum; plum, American; plum, 
beach; plum, Canada; plum, cherry; plum, Chickasaw; plum, Damson; plum, Japanese; plum,
Klamath; plum, prune; plumcot; sloe; cultivars, varieties, and/or hybrids of these.

Powdery Mildew 
{Erysiphe polygoni)
______________Use Directions______________
Begin applications prior to disease development 
and continue throughout the year on a 10- to 21- 
day interval. Make no more than 2 consecutive 
applications before switching to another 
effective fungicide with a different mode of 
action.
Crop 
Sugar beets
Specific Use Restrictions:
1) Maximum Single Application Rate: Do not exceed the maximum rate listed in the table.
2) Minimum Application Interval: 7 days
3) Do not apply more than 4 applications per year at the highest rate.
4) Do not apply more than 56 fl oz/A/year of Quadris Top Fungicide (0.73 lb azoxystrobin and 
0.46 lb difenoconazole).
5) Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
6) Do not apply more than 1.5 lb ai/A/year of azoxystrobin-containing products.
7) Quadris Top Fungicide may be applied on the day of harvest (0-day PHI).
[Optional language if label has a rate range". If 
disease pressure is high, use the highest rate.]
[Optional language if label has a single rate and 
interval range: If disease pressure is high, use 
the shortest interval.]
[Optional language if label has a rate range and 
interval range". If disease pressure is high, use 
the shortest interval and highest rate.]
The addition of a spreading/penetrating type 
adjuvant such as a non-ionic surfactant or crop 
oil concentrate or blend is advised when
__________________________________I___________ applying by ground or air.___________________
*10 fl oz product/A contains 0.13 lb azoxystrobin/A and 0.08 lb difenoconazole/A.
*14 fl oz product/A contains 0.18 lb azoxystrobin/A and 0.11 lb difenoconazole/A.________________
Application: For best results, use sufficient water volume to provide thorough coverage. Quadris 
Top Fungicide may be applied by ground, chemigation, or aerial application._____________________
Specific Use Restrictions:
1) Maximum Single Application Rate: Do not exceed the maximum rate listed in the table.
2) Minimum Application Interval: 10 days
3) Do not apply more than 3 applications per year at the highest rate.
4) Do not apply more than 55.3 fl oz/A/year of Quadris Top Fungicide (0.72 lb azoxystrobin and 
0.45 lb difenoconazole).
5) Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
6) Do not apply more than 2.0 lb ai/A/year of azoxystrobin-containing products.
7) Do not apply within 7 days of harvest (7-day PHI).
Target Diseases
Cercospora Leaf 
Spot 
(C. beticola)
Quadris Top Fungicide 
Page 51
Use Rate 
fl oz 
product/A
10-14*

7.5-8*
Tomatillo
Gray Leaf Spot 
(Stemphylium 
botryosum)
Septoria Leaf Spot 
fS. lycopersici)
Target Spot 
(Corynespora 
cassiicola)
Powdery Mildew 
(LeveiHula taurica)
A tank mixture with Dimethoate may cause crop 
injury.
Early Blight
(Alternaria solani)
Use of Adjuvants: Under certain weather 
conditions (particularly high temperatures) 
Quadris Top Fungicide in combination with high 
rates of silicone-based or oil containing 
(petroleum or crop) additives or adjuvants may 
cause injury. Do not exceed 0.125% adjuvant 
(v/v). Consult a Syngenta representative for 
more information concerning additives or 
adjuvants.
Leaf Mold 
(Fulvia fulva)
Black Mold 
(A. al tern ata)
______________Use Directions______________
Begin applications prior to disease development 
and continue throughout the year on a 7- to 10- 
day interval. Make no more than 2 consecutive 
applications before switching to another 
effective fungicide with a different mode of 
action.
[Optional language if label has a rate range: If 
disease pressure is high, use the highest rate.]
[Optional language if label has a single rate and 
interval range: If disease pressure is high, use 
the shortest interval.]
[Optional language if label has a rate range and 
interval range: If disease pressure is high, use 
the shortest interval and highest rate.]
On fresh market tomatoes, do not use adjuvants
or tank mix Quadris Top Fungicide with any EC 
__________________________________I___________ product.___________________________________
*7.5 fl oz product/A contains 0.09 lb azoxystrobin/A and 0.06 lb difenoconazole/A. 
*8 fl oz product/A contains 0.10 lb azoxystrobin/A and 0.07 lb difenoconazole/A.___________________
Application: For best results, use sufficient water volume to provide thorough coverage. Quadris
Top Fungicide may be applied by ground, chemigation, or aerial application.______________________
Complete List of Tomato Crops: Bush tomato; Cocona; Currant tomato; Garden huckleberry; Goji 
berry; Groundcherry; Naranjilla; Sunberry; Tomatillo; Tomato; Tree tomato; cultivars, varieties, and/or 
hybrids of these.__________________________________________________________________________
Specific Use Restrictions:
1) Maximum Single Application Rate: Do not exceed the maximum rate listed in the table.
2) Minimum Application Interval: 7 days
3) Do not apply more than 5 applications per year at the highest rate.
4) Do not apply more than 47 fl oz/A/year of Quadris Top Fungicide (0.6 lb azoxystrobin and 0.39 lb 
difenoconazole).
5) Do not apply until 21 days after transplanting or 35 days after seeding.
See 
complete list 
of tomato 
crops below.
Use Rate 
fl oz 
product/A
Quadris Top Fungicide 
Page 52
Including all 
cultivars 
and/or 
hybrids of 
these
Target Diseases
Anthracnose 
(Colletotrichum
spp.)
Crop 
Tomatoes

6) Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
7) Do not apply more than 0.6 lb ai/A/year of azoxystrobin-containing products.
8) May be applied the day of harvest (0-day PHI).
The addition of a spreading/penetrating type 
adjuvant such as a non-ionic based surfactant or 
crop oil concentrate or blend is advised.
Target Diseases
Foliar Diseases
______________Use Directions____________
Begin applications prior to disease onset when 
conditions are conducive for disease. Apply 
Quadris Top Fungicide on a 14- to 21-day 
schedule making no more than 2 sequential 
applications before alternating to another 
fungicide with a non-Qol (Group 11) mode of 
action.
[Optional language if label has a rate range: If 
disease pressure is high, use the highest rate.]
[Optional language if label has a single rate and 
interval range: If disease pressure is high, use 
the shortest interval.]
[Optional language if label has a rate range and 
interval range: If disease pressure is high, use
__________________________________I___________the shortest interval and highest rate.]__________ 
*10 fl oz product/A contains 0.13 lb azoxystrobin/A and 0.08 lb difenoconazole/A.
*12 fl oz product/A contains 0.16 lb azoxystrobin/A and 0.10 lb difenoconazole/A 
*14 fl oz product/A contains 0.18 lb azoxystrobin/A and 0.11 lb difenoconazole/A._________________
Application: For best results, sufficient water volume must be used to provide thorough coverage.
Quadris Top Fungicide can be applied by ground or aerial application. Use a minimum of 15 gal/A of 
water for ground applications. For aerial applications, use a minimum of 10 gal/A of water._________
Complete List of Tree Nut Crops: African nut-tree; almond; beechnut; Brazil nut; Brazilian pine; 
bunya; bur oak; butternut; Cajou nut; candlenut; cashew; chestnut; chinquapin; coconut; coquito nut; 
dika nut; ginkgo; Guiana chestnut; hazelnut (filbert); heartnut; hickory nut; Japanese horse-chestnut; 
macadamia nut; mongongo nut; monkey-pot; monkey puzzle nut; Okari nut; Pachira nut; peach palm 
nut; pecan; pequi; Pili nut; pine nut; pistachio; Sapucaia nut; tropical almond; walnut, black; walnut, 
English; yellowhorn; cultivars, varieties, and/or hybrids of these.________________________________
Specific Use Restrictions:
1) Maximum Single Application Rate: Do not exceed the maximum rate listed in the table.
2) Minimum Application Interval: 14 days
3) Do not apply more than 4 applications per year at the highest rate.
4) Do not apply more than 56 fl oz/A/year of Quadris Top Fungicide (0.73 lb azoxystrobin and 0.46 
lb difenoconazole).
5) Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
6) Do not apply more than 1.2 lb ai/A/year of azoxystrobin-containing products.
7) Do not apply within 45 days of harvest (45-day PHI).
Quadris Top Fungicide 
Page 53
See specific 
Directions for 
Almonds 
Filberts 
Pecans 
Pistachios
Crop
Tree Nuts, 
Crop Group 
14-12 
Beechnut 
Brazil Nut 
Butternut 
Cashew 
Chestnut 
Macadamia 
Walnut
Use Rate 
fl oz 
product/A
10-14*

QuadrisTop Fungicide
Page 54

Early Blight
(Alternaria spp.)
Brown Spot 
(Alternaria 
alternate)
Powdery Mildew 
(Erysiphe
cichoracearum)
The addition of a spreading/penetrating type 
adjuvant such as a non-ionic based surfactant or 
crop oil concentrate or blend is advised.
[Optional language if label has a rate range: If 
disease pressure is high, use the highest rate.]
For listing of 
crops in this 
group, see 
below.
______________Use Directions______________
Begin applications prior to disease development 
and continue throughout the year on a 7- to 14- 
day interval. Make no more than 2 consecutive 
applications before switching to another 
effective fungicide with a different mode of 
action.
[Optional language if label has a rate range and 
interval range: If disease pressure is high, use 
the shortest interval and highest rate.]
[Optional language if label has a single rate and 
interval range: If disease pressure is high, use 
the shortest interval.]
Crop 
Vegetables, 
Tuberous 
and Corm, 
Subgroup 
1C
Rust 
(Uromyces betae, 
Puccinia helianthi)
Black Dot 
(Colletotrichum
coccodes)
QuadrisTop Fungicide
Page 55
See
Potatoes for 
specific use 
directions.
Septoria Leaf Spot
_______________(Septoria spp.)_____|______________________________________________________
*8 fl oz product/A contains 0.10 lb azoxystrobin/A and 0.07 lb difenoconazole/A.
*14 fl oz product/A contains 0.18 lb azoxystrobin/A and 0.11 lb difenoconazole/A.__________________
Application: For best results, sufficient water volume must be used to provide thorough coverage.
Quadris Top Fungicide can be applied by ground or aerial application. Use a minimum of 15 gal/A of 
water for ground applications. For aerial applications, use a minimum of 10 gal/A of water._________
Complete List of Vegetables, Tuberous and Corm Subgroup 1C: Arracacha, Arrowroot,
Artichoke (Chinese and Jerusalem), Canna (Edible), Cassava (bitter and sweet), Chayote (root), 
Chufa, Dasheen , Ginger, Leren, Sweet Potato, Tanier, Tumeric, Yam (bean and true)._____________
Specific Use Restrictions:
1) Maximum Single Application Rate: Do not exceed the maximum rate listed in the table.
2) Minimum Application Interval: 7 days
3) Do not apply more than 3 applications per year at the highest rate.
4) Do not apply more than 55.3 fl oz/A/year of Quadris Top Fungicide (0.72 lb azoxystrobin and 0.45 
lb difenoconazole).
5) Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.
6) Do not apply more than 2.0 lb ai/A/year of azoxystrobin-containing products.
7) Do not apply within 14 days of harvest (14-day PHI).
Target Diseases 
Ascochyta Leaf Spot 
(A. cynarae)
Use Rate 
fl oz 
product/A
8-14*

1)
2)
3)
4)
5)
6)
7)
8)
[Not for use in 
California.]
______ Crop
Watercress
____________Use Directions__________
For best activity, apply Quadris Top 
Fungicide prior to or early in the disease 
development. An adjuvant may be added 
at specified rates. Apply on a 7-14 day 
interval. For applications made to 
watercress, production fields must be 
drained of water at least 24 hours prior to 
application and water must not be 
reapplied to the field for a minimum of 24 
hours following the application.
Make no more than two sequential 
applications before alternating to a 
_______________________________________I___________fungicide with a different mode of action.
*10 fl oz product/A contains 0.13 lb azoxystrobin/A and 0.08 lb difenoconazole/A.
*14 fl oz product/A contains 0.18 lb azoxystrobin/A and 0.11 lb difenoconazole/A.________________
Application: For best results, sufficient water volume must be used to provide thorough coverage. 
Quadris Top Fungicide can be applied by ground, chemigation, or aerial application. For aerial 
applications, use a minimum of 5 gal/A of water. Applicators must use care in making applications 
near non-target aquatic habitats.__________________________________________________________
Specific Use Restrictions:
Maximum Single Application Rate: Do not exceed the maximum rate listed in the table.
Minimum Application Interval: 7 days
Do not apply more than 4 applications per year at the highest rate.
Do not apply directly to water and do not allow water in a treated field for at least 24 hours. 
Do not apply more than 56 fl QzJNyear of Quadris Top Fungicide (0.73 lb azoxystrobin and 0.46 
lb difenoconazole).
Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products. 
Do not apply more than 1.5 lb ai/A/year of azoxystrobin-containing products.
Do not apply more than 0.75 lb ai of azoxystrobin-containing products per acre per cutting. 
Do not apply Quadris Top Fungicide within 30 days of harvest (30-day PHI).
Target Diseases 
Cercospora leafspot 
{Cercospora spp.)
Quadris Top Fungicide 
Page 56
Use Rate 
fl oz 
product/A
10-14*

Quadris Top Fungicide Rate Conversion Table for Food Use
1)
2)
3)
4)
5)
6)
7)
Brown Spot
{Bipolaris spp.)
______________Use Directions___________
Apply 15 fl oz/A at both booting and heading. 
Minimum re-treatment interval is 14 days.
8)
9)
10) Do not apply Quadris Top Fungicide within 28 days of harvest (28-day PHI).
11) Do not drain water from treated rice fields into ponds used for aquaculture of fish or crustacean.
12) Do not use water drained from treated field to irrigate other crops.
*15 fl oz product/A contains 0.123 lb difenoconazole/A and 0.196 lb azoxystrobin/A._______________
Application: For best results, sufficient water volume must be used to provide thorough coverage. 
Quadris Top Fungicide can be applied by ground or aerial application. For aerial applications, use a 
minimum of 5 gal/A of water. Applicators must use care in making applications near non-target 
aquatic habitats._________________________________________________________________________
Specific Use Restrictions:
Maximum Single Application Rate: Do not exceed the maximum rate listed in the table.
Minimum Application Interval: 14 days
Do not apply more than 2 applications per year at the highest rate.
Do not treat rice fields used for aquaculture offish or crustacean.
Do not apply when weather conditions favor drift from treated areas to non-target aquatic habitat. 
Do not allow release of irrigation or flood water for at least 14 days after the last application. 
Do not apply more than 30 fl oz/A/year of Quadris Top Fungicide (0.39 lb azoxystrobin and 0.25 
lb difenoconazole).
Do not apply more than 0.7 lb ai/A/year of azoxystrobin-containing products.
Do not apply more than 0.244 lb ai/A/year of difenoconazole-containing products.
Quadris Top Fungicide 
Page 57
Crop 
Wild Rice
Target Diseases 
Helminthosporium 
leaf blight
Fl oz product/acre
________7.5 
________8________
10 ________
11.6
12________
14 ________
15 ________
15.4
Lb ai azoxystrobin 
________0.09 
________0.10 
________0.13 
________0.15 
________0.16
_______0.18 
_______0.19
0.20
Lb ai difenoconazole 
________0.06_________ 
________0.07_________ 
________0.08_________
_______0.09________
_______0.10 ________ 
_______0J1________ 
_______0.12________
0.13
Use Rate 
fl oz 
product/A
15*

CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY
1
NOTICE: Read the entire Directions for Use and Conditions of Sale and Limitation of 
Warranty and Liability before buying or using this product. If the terms are not 
acceptable, return the product at once, unopened, and the purchase price will be 
refunded.
The Directions for Use of this product must be followed carefully. It is impossible to 
eliminate all risks inherently associated with the use of this product. Crop injury 
ineffectiveness or other unintended consequences may result because of such factors 
as manner of use or application, weather or crop conditions, presence of other materials 
or other influencing factors in the use of the product, which are beyond the control of 
SYNGENTA CROP PROTECTION. LLC or Seller. To the extent permitted by 
applicable law. Buyer and User agree to hold SYNGENTA and Seller harmless for any 
claims relating to such factors.
SYNGENTA and Seller offer this product, and Buyer and User accept it. subject to the 
foregoing Conditions of Sale and Limitation of Warranty and Liability, which may not be 
modified except by written agreement signed by a duly authorized representative of 
SYNGENTA.
To the extent permitted by applicable law. in no event shall SYNGENTA be liable for 
any incidental, consequential or special damages resulting from the use or handling of 
this product. TO THE EXTENT PERMITTED BY APPLICABLE LAW, THE
EXCLUSIVE REMEDY OF THE USER OR BUYER, AND THE EXCLUSIVE LIABILITY 
OF SYNGENTA AND SELLER FOR ANY AND ALL CLAIMS, LOSSES, INJURIES 
OR DAMAGES (INCLUDING CLAIMS BASED ON BREACH OF WARRANTY, 
CONTRACT, NEGLIGENCE, TORT, STRICT LIABILITY OR OTHERWISE)
RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, SHALL BE THE 
RETURN OF THE PURCHASE PRICE OF THE PRODUCT OR, AT THE ELECTION 
OF SYNGENTA OR SELLER, THE REPLACEMENT OF THE PRODUCT.
SYNGENTA warrants that this product conforms to the chemical description on the label 
and is reasonably fit for the purposes stated in the Directions for Use. subject to the 
inherent risks referred to above, when used in accordance with directions under normal 
use conditions. To the extent permitted by applicable law: (1) this warranty does not 
extend to the use of this product contrary to label instructions, or under conditions not 
reasonably foreseeable to or beyond the control of Seller or SYNGENTA, and. (2) Buyer 
and User assume the risk of any such use. TO THE EXTENT PERMITTED BY 
APPLICABLE LAW. SYNGENTA MAKES NO WARRANTIES OF MERCHANTABILITY 
OR OF FITNESS FOR A PARTICULAR PURPOSE NOR ANY OTHER EXPRESS OR 
IMPLIED WARRANTY EXCEPT AS WARRANTED BY THIS LABEL.
QuadrisTop Fungicide
Page 58

STORAGE AND DISPOSAL
Do not contaminate water, food, or feed by storage or disposal.
Pesticide Storage
Pesticide Disposal
J
Container Handling [less than or equal to 5 gallons]
Container Handling [greater than 5 gallons]
Pesticide wastes may be toxic. Improper disposal of unused pesticide, spray mixture 
or rinse water is a violation of Federal Law. If these wastes cannot be used according 
to label instructions, contact your State Pesticide or Environmental Control Agency, or 
the Hazardous Waste Representative at the nearest EPA Regional Office for guidance 
in proper disposal methods.
Non-refillable container. Do not reuse or refill this container. Triple rinse container (or 
equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining 
contents into application equipment or a mix tank. Fill the container % full with water. 
Replace and tighten closures. Tip container on its side and roll it back and forth, 
ensuring at least one complete revolution, for 30 seconds. Stand the container on its 
end and tip it back and forth several times. Turn the container over onto its other end 
and tip it back and forth several times. Empty the rinsate into application equipment or 
a mix tank or store rinsate for later use or disposal. Repeat this procedure two more 
times. Then offer for recycling if available or puncture and dispose of in a sanitary 
landfill, or by incineration, or by other procedures approved by state and local 
authorities.
Container Handling [greater than 5 gallons]
Non-refillable container. Do not reuse or refill this container. Triple rinse container (or 
equivalent) promptly after emptying. Triple rinse as follows: empty the remaining 
contents into application equipment or a mix tank and drain for 10 seconds after the flow 
begins to drip. Fill the container % full with water and recap. Shake for 10 seconds. 
Pour rinsate into application equipment or a mix tank or store rinsate for later use or 
disposal. Drain for 10 seconds after the flow begins to drip. Repeat this procedure two 
more times. Then offer for recycling if available or puncture and dispose of in a sanitary 
landfill, or by incineration, or by other procedures approved by state and local 
authorities.
Store in original container only. Store in a cool, dry and well-ventilated place. Protect 
from excessive heat. Keep container closed when not in use. Do not store near food or 
feed.
QuadrisTop Fungicide
Page 59

CONTAINER IS NOT SAFE FOR FOOD, FEED, OR DRINKING WATER.
©20XX Syngenta
Quadris Top® and the SYNGENTA Logo are Trademarks of a Syngenta Group 
Company
Quadris Top Fungicide 
Page 60
QUADRIS TOP 1313 MAS 0218 AMEND-D 0219 - sb - 12/10/19 
000100-01313.20190201 D.QUADRIS TOP-AMEND-021 9
For non-emergency (e.g., current product information), call 
Syngenta Crop Protection at 1-800-334-9481.
Refillable container. Refill this container with pesticide only. Do not reuse the container 
for any other purpose. Cleaning the container before final disposal is the responsibility of 
the person disposing of the container. Cleaning before refilling is the responsibility of the 
person refilling. To clean container before final disposal, empty the remaining contents 
from this container into application equipment or mix tank. Fill the container about 10 
percent full with water. Agitate vigorously or recirculate water with the pump for 2 
minutes. Pour or pump rinsate into application equipment or rinsate collection system. 
Repeat this rinsing procedure two more times. Then offer for recycling if available or 
puncture and dispose of in a sanitary landfill, or by incineration, or by other procedures 
approved by state and local authorities.
Manufactured for:
Syngenta Crop Protection, LLC
P.O. Box 18300
Greensboro, North Carolina 27419-8300