crop-chem-docs/corpus/epa_ppls/100-1352.md

# MAXIM QUATTRO

- EPA Reg No: **100-1352**
- Registrant: SYNGENTA CROP PROTECTION, LLC
- Signal word: Caution
- Active ingredients: Thiabendazole (26.5%); Fludioxonil (3.32%); Metalaxyl-M (2.65%); Azoxystrobin (1.33%)
- Label accepted: 2025-12-03
- Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000100-01352-20251203.pdf

---
December 3rd, 2025 
 
Ricky Kyaw 
Regulatory Product Manager 
Syngenta Crop Protection, Inc. 
P.O Box 18300 
Greensboro, NC 27419 
 
Subject: Label Amendment - Registration Review Mitigation for Thiabendazole 
 Product Name: Maxim Quattro 
 EPA Registration Number: 100-1352 
Case Number: 482812 
Application Dates: 12/14/2020 
 
Dear Ricky Kyaw: 
 
The Agency, in accordance with the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), 
as amended, has completed reviewing all the information submitted with your application to 
support the Registration Review of the above referenced product in connection with the 
Thiabendazole Interim Decision, and has concluded that your submission is acceptable. The 
label referred to above, submitted in connection with registration under FIFRA, as amended, is 
acceptable. 
 
Should you wish to add/retain a reference to the company’s website on your label, then please 
be aware that the website becomes labeling under the Federal Insecticide, Fungicide, and 
Rodenticide Act and is subject to review by the Agency. If the website is false or misleading, the 
product would be misbranded and unlawful to sell or distribute under FIFRA section 12(a)(1)(E). 
40 CFR 156.10(a)(5) list examples of statements EPA may consider false or misleading. In 
addition, regardless of whether a website is referenced on your product’s label, claims made on 
the website may not substantially differ from those claims approved through the registration 
process. Therefore, should the Agency find or if it is brought to our attention that a website 
contains false or misleading statements or claims substantially differing from the EPA approved 
registration, the website will be referred to the EPA’s Office of Enforcement and Compliance 
Assurance.

Page 2 of 2 
EPA Reg. No. 100-1352 
Case No. 482812 
 
A stamped copy of your labeling is enclosed for your records. This labeling supersedes all 
previously accepted labeling and must be used at your next label printing. You must submit one 
copy of the final printed labeling before you release the product for shipment with the new 
labeling. In accordance with 40 CFR 152.130(c), you may distribute or sell this product under 
the previously approved labeling for 12 months from the date of this letter. After 12 months, 
you may only distribute or sell this product if it bears this new revised labeling or subsequently 
approved labeling. “To distribute or sell” is defined under FIFRA section 2(gg) and its 
implementing regulation at 40 CFR 152.3. 
 
If you have any questions about this letter, please contact Nicholas Barnett by phone at 513-
569-7643, or via email at barnett.nicholas@epa.gov. 
 
 Sincerely, 
 
 
 
 
Maryam K. Muhammad-Perch, Team Lead 
Risk Management and Implementation Branch 4 
Pesticide Re-Evaluation Division 
Office of Pesticide Programs 
 
 
 
 
 
ENCLOSURE: Stamped Label

THIABENDAZOLE GROUP 1 FUNGICIDE
MEFENOXAM GROUP 4 FUNGICIDE
AZOXYSTROBIN GROUP 11 FUNGICIDE
FLUDIOXONIL GROUP 12 FUNGICIDE
Maxim® Quattro
Fungicide
A seed treatment for the control of listed fungal diseases of field corn, sweet corn and 
popcorn.
Active Ingredients:
Fludioxonil*:............................................................................................................. 3.32%
Mefenoxam**:.......................................................................................................... 2.65%
Azoxystrobin***: ...................................................................................................... 1.33%
Thiabendazole****: ................................................................................................ 26.50%
Other Ingredients: 66.20%
Total: 100.00%
*CAS No. 131341-86-1
**CAS Nos. 70630-17-0 and 69516-34-3
***CAS No. 131860-33-8
****CAS No. 148-79-8
Maxim Quattro is a flowable concentrate for seed treatment containing 0.31 lb 
fludioxonil, 0.25 lb mefenoxam, 0.12 lb azoxystrobin and 2.50 lb thiabendazole per 
gallon.
KEEP OUT OF REACH OF CHILDREN.
CAUTION
[See additional precautionary statements and directions for use inside booklet].
EPA Reg. No. 100-1352
EPA Est. No.
15 gallons
30 gallons
110 gallons
265 gallons
Net Contents
12/03/2025
100-1352

Maxim Quattro
Page 2
FIRST AID
If in eyes x Hold eye open and rinse slowly and gently with water for 15-20
minutes.
x Remove contact lenses, if present, after the first 5 minutes, then 
continue rinsing eye.
x Call a poison control center or doctor for treatment advice.
If on skin or 
clothing
x Take off contaminated clothing.
x Rinse skin immediately with plenty of water for 15-20 minutes.
x Call a poison control center or doctor for treatment advice.
If swallowed x Call a poison control center or doctor immediately for treatment 
advice.
x Have person sip a glass of water if able to swallow.
x Do not induce vomiting unless told to do so by a poison control 
center or doctor.
x Do not give anything by mouth to an unconscious person.
Have the product container with you when calling a poison control center or doctor, or 
going for treatment.
HOT LINE NUMBER
For 24-Hour Medical Emergency Assistance (Human or Animal) or 
Chemical Emergency Assistance (Spill, Leak, Fire, or Accident), 
Call 
1-800-888-8372
PRECAUTIONARY STATEMENTS
Hazards to Humans and Domestic Animals
CAUTION
Causes moderate eye irritation. Harmful if absorbed through skin. Harmful if 
swallowed. Avoid contact with eyes, skin, or clothing. Prolonged or frequently repeated 
skin contact may cause allergic reactions in some individuals. Wash thoroughly with 
soap and water after handling and before eating, drinking, chewing gum, using tobacco
or using the toilet. Remove and wash contaminated clothing before reuse.
Personal Protective Equipment (PPE)
Mixers, loaders, applicators and other handlers must wear:
x Long-sleeved shirt and long pants
x Chemical-resistant gloves made of barrier laminate, butyl rubber t14 mils, nitrile 
rubber t14 mils, neoprene rubber t14 mils, polyvinyl chloride (PVC) t14 mils, or 
Viton® t14 mils
x Shoes plus socks

Maxim Quattro
Page 3
Follow manufacturer’s instructions for cleaning/maintaining PPE. If no such instructions 
for washables exist, use detergent and hot water. Keep and wash PPE separately from 
other laundry.
Engineering Controls
When handlers use closed systems in a manner that meets the requirements listed in 
the Worker Protection Standard (WPS) for agricultural pesticides [40 CFR 170.240(d)(4-
6)], the handler PPE requirements may be reduced or modified as specified in the WPS.
User Safety Recommendations
Users should:
x Wash hands before eating, drinking, chewing gum, using tobacco, or using the toilet.
x Remove clothing/PPE immediately if pesticides get inside. Then wash thoroughly 
and put on clean clothing.
x Remove PPE immediately after handling this product. Wash the outside of gloves 
before removing. As soon as possible, wash thoroughly and change into clean 
clothing.
Environmental Hazards
This product is toxic to fish, aquatic invertebrates, oysters and shrimp. Do not apply 
directly to water, or to areas where surface water is present, or to intertidal areas below 
the mean high water mark. Do not contaminate water when disposing of equipment 
washwater or rinsate.
Non-Target Organism Advisory Statement
This product may adversely impact non-target organisms feeding on treated seeds. 
Protect the non-target organisms by following label directions intended to minimize 
availability of treated seed to non-target organisms.
x Cover or collect treated seeds spilled during loading and planting in areas (such
as in row ends).
x Dispose of all excess treated seed by burying seed away from bodies of water.
Groundwater Advisory
Azoxystrobin, Mefenoxam and a degradate of Azoxystrobin are known to leach through 
soil into groundwater under certain conditions as a result of label use. Fludioxonil has 
properties and characteristics associated with chemicals detected in groundwater. 
These chemicals may leach into groundwater if used in areas where soils are 
permeable, particularly where the water table is shallow.

Maxim Quattro
Page 4
CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY
NOTICE: Read the entire Directions for Use and Conditions of Sale and Limitation of 
Warranty and Liability before buying or using this product. If the terms are not 
acceptable, return the product at once, unopened, and the purchase price will be 
refunded.
The Directions for Use of this product must be followed carefully. It is impossible to 
eliminate all risks inherently associated with the use of this product. Crop injury, 
ineffectiveness or other unintended consequences may result because of such factors 
as manner of use or application, weather or crop conditions, presence of other materials 
or other influencing factors in the use of the product, which are beyond the control of 
SYNGENTA CROP PROTECTION, LLC or Seller. To the extent permitted by 
applicable law, Buyer and User agree to hold SYNGENTA and Seller harmless for any 
claims relating to such factors.
SYNGENTA warrants that this product conforms to the chemical description on the label 
and is reasonably fit for the purposes stated in the Directions for Use, subject to the 
inherent risks referred to above, when used in accordance with directions under normal 
use conditions. To the extent permitted by applicable law: (1) this warranty does not 
extend to the use of this product contrary to label instructions or under conditions not 
reasonably foreseeable to or beyond the control of Seller or SYNGENTA, and (2) Buyer
and User assume the risk of any such use. To the extent permitted by applicable law, 
SYNGENTA MAKES NO WARRANTIES OF MERCHANTABILITY OR OF FITNESS 
FOR A PARTICULAR PURPOSE NOR ANY OTHER EXPRESS OR IMPLIED 
WARRANTY EXCEPT AS WARRANTED BY THIS LABEL.
To the extent permitted by applicable law, in no event shall SYNGENTA be liable for 
any incidental, consequential or special damages resulting from the use or handling of 
this product. TO THE EXTENT PERMITTED BY APPLICABLE LAW, THE 
EXCLUSIVE REMEDY OF THE USER OR BUYER, AND THE EXCLUSIVE LIABILITY 
OF SYNGENTA AND SELLER FOR ANY AND ALL CLAIMS, LOSSES, INJURIES 
OR DAMAGES (INCLUDING CLAIMS BASED ON BREACH OF WARRANTY, 
CONTRACT, NEGLIGENCE, TORT, STRICT LIABILITY OR OTHERWISE) 
RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, SHALL BE THE 
RETURN OF THE PURCHASE PRICE OF THE PRODUCT OR, AT THE ELECTION 
OF SYNGENTA OR SELLER, THE REPLACEMENT OF THE PRODUCT.
SYNGENTA and Seller offer this product, and Buyer and User accept it, subject to the 
foregoing Conditions of Sale and Limitation of Warranty and Liability, which may not be 
modified except by written agreement signed by a duly authorized representative of 
SYNGENTA.

Maxim Quattro
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DIRECTIONS FOR USE
It is a violation of Federal law to use this product in a manner inconsistent with its 
labeling.
For Commercial Use only. Do not use in hopper box, planter box, slurry box, or other 
farmer-applied applications.
Maxim Quattro must be used only in accordance with recommendations on this label or 
in separately published Syngenta supplemental labeling approved by EPA for this 
product.
Do not apply this product in a way that will contact workers or other persons, either 
directly or through drift. Only protected handlers may be in the area during application. 
For any requirements specific to your State or Tribe, consult the agency responsible for 
pesticide regulation.
Maximum usage when applying both metalaxyl- and mefenoxam-containing 
products to the same crop within the same season: Do not apply more than the 
maximum yearly total application rate for the active ingredient as stated on the label of 
the product containing the lowest yearly total on that crop.
FAILURE TO FOLLOW DIRECTIONS AND PRECAUTIONS ON THIS LABEL MAY 
RESULT IN CROP INJURY, POOR DISEASE CONTROL, AND/OR ILLEGAL
RESIDUES.
Treatment of highly mechanically scarred or damaged seed, or seed known to be of low 
vigor and poor quality, except for the purpose of curative control of existing disease 
pests, may result in reduced germination and/or reduction of seed and seedling vigor. 
Treat using equipment similar to that planned for treating the total seed lot. Conduct 
germination tests on a small portion of seed before committing the total seed lot to a 
selected seed treatment. Due to seed quality and seed storage conditions beyond the 
control of Syngenta, no claims are made to guarantee the germination of carry-over 
treated seed.
PRODUCT INFORMATION
Maxim Quattro seed treatment fungicide is a broad-spectrum fungicide that consists of 
four fungicide active ingredients (fludioxonil, azoxystrobin, mefenoxam and 
thiabendazole). All the active ingredients have a different mode of action against fungal 
pathogens. This fungicide seed treatment is recommended for control of many 
important fungal plant diseases. Maxim Quattro may be applied in tank mixes, or 
sequentially with other EPA-registered seed treatment pesticide products such as 
Cruiser® brand insecticides and Avicta® brand nematicides. If using Maxim Quattro in 
a tank mixture with other seed treatment products, observe all directions for use, 
crops/sites, use rates, dilution ratios, precautions, and limitations which appear on the 
tank-mix partner label(s). Do not exceed any label dosage and the most restrictive label

Maxim Quattro
Page 6
precautions and limitations must be followed. This product must not be mixed with any 
product which prohibits such mixing.
All applications must be made according to the use directions that follow. Apply Maxim 
Quattro as a seed treatment following the guidelines specified in the Directions for Use 
section of this label.
RESISTANCE MANAGEMENT
THIABENDAZOLE GROUP 1 FUNGICIDE
MEFENOXAM GROUP 4 FUNGICIDE
AZOXYSTROBIN GROUP 11 FUNGICIDE
FLUDIOXONIL GROUP 12 FUNGICIDE
For resistance management, please note that Maxim Quattro contains thiabendazole, a 
Group 1 fungicide; mefenoxam, a Group 4 fungicide; azoxystrobin, a Group 11 
fungicide; and fludioxonil, a Group 12 fungicide. Any fungal population may contain 
individuals naturally resistant to Maxim Quattro, and other Group 1, Group 4, Group 11, 
or Group 12 fungicides. A gradual or total loss of pest control may occur over time if 
these fungicides are used repeatedly in the same fields. Appropriate resistance-
management strategies should be followed. 
Thiabendazole belongs to the methyl-benzimidazole carbamate class of chemistry 
which disrupts ß-tubulin assembly in mitosis. Mefenoxam belongs to the phenylamide 
class of chemistry which interferes with fungal RNA synthesis. Azoxystrobin belongs to 
the strobilurin class of chemistry which disrupts cellular respiration and energy 
generation. Fludioxonil belongs to the phenylpyrrole class of chemistry which interferes 
with osmotic signal transduction.
To delay fungicide resistance, take one or more of the following steps:
x Rotate the use of Maxim Quattro or other Group 1, Group 4, Group 11, or Group 12 
fungicides within a growing season sequence with different groups that control the 
same pathogens.
x Use tank mixtures with fungicide from a different group that are equally effective on 
the target pest when such use is permitted. Use at least the minimum application 
rate as labeled by the manufacturer.
x Adopt an integrated disease management program for fungicide use that includes 
scouting, uses historical information related to pesticide use, and crop rotation, and 
which considers host plant resistance, impact of environmental conditions on 
disease development, disease thresholds, as well as cultural, biological and other 
chemical control practices.
x Where possible, make use of predictive disease models to effectively time fungicide 
applications. Note that using predictive models alone is not sufficient to manage 
resistance.
x Monitor treated fungal populations for resistance development.

Maxim Quattro
Page 7
x Contact your local extension specialist or certified crop advisor for any additional 
pesticide resistance-management and/or IPM recommendations for specific crop 
and pathogens.
x For further information or to report suspected resistance contact Syngenta at 1-866-
Syngent(a) (866-796-4368). You can also contact your pesticide distributor or 
university extension specialist to report resistance.
MIXING PROCEDURES
Apply Maxim Quattro as a water-based slurry using seed treatment application 
equipment that will provide uniform coverage on the seed surface. Consult the 
manufacturer of the application equipment being used for calibration and operation 
procedures.
Maxim Quattro mixes easily with water and other water-based seed treatments 
manufactured by Syngenta. When mixing with products from other manufacturers, the 
compatibility should be tested prior to use by conducting a jar test: mix all intended seed 
treatments with the appropriate amount of water in a clear glass container. Mix well and 
allow mixture to sit for one hour. Remix and observe for incompatibility.
Mixing Maxim Quattro with tank-mix partners: Add ½ of the required water to the mix 
tank and turn on the agitation. Mechanical agitation is preferred. If using wettable 
powders, add them first to clean water allowing them to completely disperse prior to 
adding Maxim Quattro or other products. Allow each tank-mix partner to completely 
disperse before adding the next product. Add the remaining amount of water and 
agitate. Maintain agitation until the entire slurry mixture has been used. 
x Treater must ensure an EPA-approved dye or colorant has been used that imparts 
an unnatural color to the seed as stated in 40 CFR 153.155(c).
x Allow seed to dry prior to bagging.
SEED CONTAINER LABEL REQUIREMENTS
The Federal Seed Act requires that containers of treated seeds shall be labeled with the 
following statements:
x This seed has been treated with fludioxonil, mefenoxam, azoxystrobin and 
thiabendazole fungicides. 
x Do not use for feed, food, or oil purposes. 
In addition, include the following statements on containers of seeds treated with Maxim 
Quattro:
x Non-Target Organism Advisory Statement: This product may adversely impact 
non-target organisms feeding on treated seeds. Protect the non-target organisms

Maxim Quattro
Page 8
by following label directions intended to minimize availability of treated seed to 
non-target organisms.
o Cover or collect treated seeds spilled during loading and planting in areas 
(such as in row ends).
o Dispose of all excess treated seed by burying seed away from bodies of 
water.
x Ground Water Advisory: Mefenoxam is known to leach through soil into 
groundwater under certain conditions as a result of label use. This chemical may 
leach into groundwater if used in areas where soils are permeable, particularly 
where the water table is shallow.
x Store away from feeds and foodstuffs. 
x Do not allow children, pets, or livestock to have access to treated seed.
x Wear long-sleeved shirt, long pants and chemical-resistant gloves when handling 
treated seed.
x Treated seed must be planted into the soil at a depth greater than 1 inch.
x Do not contaminate water bodies when disposing of planting equipment 
washwaters.
x Dispose of seed packaging in accordance with local requirements.
x Excess treated seed may be used for ethanol production only if:
(1) By-products are not used for livestock feed, and
(2) No measurable residues of pesticide remain in the ethanol by-products 
that are used in agronomic practice.
x In the event of crop failure or harvest of a crop grown from seed treated with 
Maxim Quattro, crops may be replanted according to the following schedule:
Immediate Plantback Interval Table
Alfalfa
Cereal Grains: Barley, Corn, Oat, Rye, Triticale and Wheat
Cucurbit Vegetables Crop Group 9
Head and Stem Brassica Crop Subgroup 5A
Onion, Bulb, Crop Subgroup 3-07A
Peas, Dried Shelled: Chickpea (Garbanzo Bean), Field Pea, Lentil, and Pigeon Pea
Root Vegetables (Except Sugarbeet) Crop Subgroup 1B
Soybean
Spinach
Sweet Potato

Maxim Quattro
Page 9
x For any other crops the minimum plantback interval is 30 days from the date 
seeds treated with Maxim Quattro were planted.
x Corn forage may not be grazed until 30 days after planting.

Maxim Quattro
Page 10
DIRECTIONS FOR USE
Crop
Target 
Diseases
Use Rate
(mg active 
ingredient 
per kernel*)
Use Rate
(fl oz/80,000 
kernel count) Remarks
Corn
Field
Pop
Sweet
(includes 
seed 
production)
Seed-borne and 
soil-borne fungi 
causing decay, 
damping-off, and 
seedling blight.
Seed-borne 
head smut 
(Sporisorium 
reilianum
)
Seedling 
damping-off 
(Rhizoctonia
spp., Penicillium
spp., Pythium
spp and 
Fusarium spp.)
0.0544 –
0.0736 mg
0.39 – 0.53 fl 
oz
With a target rate of 
0.064 mg active 
ingredient per kernel,
the following rates for 
the active ingredient 
components (mg active 
ingredient per kernel)
will be applied:*
0.0025 mg azoxystrobin
0.0065 mg fludioxonil
0.005 mg mefenoxam
0.05 mg thiabendazole
Treated sweet corn 
should be planted and 
not carried over to the 
following year.
See Apron® XL label for 
control of systemic 
downy mildew protection 
in sweet corn.

Maxim Quattro
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STORAGE AND DISPOSAL
Do not contaminate water, food, or feed by storage or disposal.
Pesticide Storage
Store in a cool, dry place.
Pesticide Disposal
Pesticide wastes may be toxic. Improper disposal of unused pesticide, spray mixture, 
or rinse water is a violation of Federal law. If these wastes cannot be used according to 
label instructions, contact your State Pesticide or Environmental Control Agency, or the 
Hazardous Waste Representative at the nearest EPA Regional Office for guidance in 
proper disposal methods.
For minor spills, leaks, etc., follow all precautions indicated on this label and clean up 
immediately. Take special care to avoid contamination of equipment and facilities during 
cleanup procedures and disposal of wastes. In the event of a major spill, fire, or other 
emergency call 1-800-888-8372, day or night.
Container Handling [less than or equal to 5 gallons]
Non-refillable container. Do not reuse or refill this container. Triple rinse container (or 
equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining 
contents into application equipment or a mix tank and drain for 10 seconds after the flow 
begins to drip. Fill the container ¼ full with water and recap. Shake for 10 seconds. 
Pour rinsate into application equipment or a mix tank or store rinsate for later use and
disposal. Drain for 10 seconds after the flow begins to drip. Repeat this procedure two 
more times. Then offer for recycling if available or puncture and dispose of in a sanitary 
landfill, or by incineration, or by other procedures approved by state and local 
authorities.
Container Handling [greater than 5 gallons – mini-bulk]
Non-refillable container. Do not reuse or refill this container. Triple rinse container (or 
equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining 
contents into application equipment or a mix tank. Fill the container ¼ full with water. 
Replace and tighten closures. Tip container on its side and roll it back and forth, 
ensuring at least one complete revolution, for 30 seconds. Stand the container on its 
end and tip it back and forth several times. Turn the container over onto its other end 
and tip it back and forth several times. Empty the rinsate into application equipment or 
a mix tank or store rinsate for later use or disposal. Repeat this procedure two more 
times. Then offer for recycling if available or puncture and dispose of in a sanitary 
landfill, or by incineration, or by other procedures approved by state and local 
authorities

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Container Handling [greater than 5 gallons - bulk]
Refillable container. Refill this container with pesticide only. Do not reuse this container 
for any other purpose. Cleaning the container before final disposal is the responsibility 
of the person disposing of the container. Cleaning before refilling is the responsibility of 
the person refilling. To clean container before final disposal, empty the remaining 
contents from this container into application equipment or mix tank. Fill the container 
about 10 percent full with water. Agitate vigorously or recirculate water with the pump 
for 2 minutes. Pour or pump rinsate into application equipment or rinsate collection 
system. Repeat this rinsing procedure two more times. Then offer for recycling if 
available or puncture and dispose of in a sanitary landfill, or by incineration, or by other 
procedures approved by state and local authorities.
CONTAINER IS NOT SAFE FOR FOOD, FEED, OR DRINKING WATER.
Maxim®, Apron® XL, Avicta®, Cruiser®, the ALLIANCE FRAME, 
the SYNGENTA Logo and the PURPOSE ICON
are Trademarks of a Syngenta Group Company
Viton® trademark of E. I. du Pont de Nemours and Company
©20XX Syngenta
For non-emergency (e.g., current product information) call
Syngenta Crop Protection at 1-800-334-9481.
Manufactured for:
Syngenta Crop Protection, LLC
P.O. Box 18300
Greensboro, North Carolina 27419-8300
Maxim Quattro 1352 MAS 0919 AMEND 1220-CL – jeb – 12/08/2020
000100-01352.20201211.MAXIM-QUATTRO-AMEND-1220-CL.pdf