crop-chem-docs/corpus/epa_ppls/100-1385.md

# FLEXSTAR GT 3.5 HERBICIDE

- EPA Reg No: **100-1385**
- Registrant: SYNGENTA CROP PROTECTION, LLC
- Signal word: Caution
- Active ingredients: Sodium salt of fomesafen (5.88%); Glyphosate (22.4%)
- Label accepted: 2019-09-20
- Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000100-01385-20190920.pdf

---
UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 
 WASHINGTON, DC 20460 
 OFFICE OF CHEMICAL SAFETY 
AND POLLUTION PREVENTION 
September 20, 2019 
O
dette Alexander- Watkins 
Senior Regulatory Product Manager 
Syngenta Crop Protection, LLC 
P.O.Box 18300 
Greensboro, NC 27419 
S
ubject: Registration Review Label Mitigation for Fomesafen 
Product Name: FLEXSTAR® GT 3.5 HERBICIDE 
E
PA Registration Number: 100-1385 
A
pplication Date: 06/26/2018 
Decision Number: 555241 
Dear Ms. Alexander-Watkins: 
The Agency, in accordance with the Federal Insecticide, Fungicide and Rodenticide Act 
(FIFRA), as amended, has completed reviewing all of the information submitted with your 
application to support the Registration Review of the above referenced product in connection 
with the Fomesafen Interim Decision, and has concluded that your submission is acceptable. The 
label referred to above, submitted in connection with registration under FIFRA, as amended, is 
acceptable. 
Should you wish to add/retain a reference to the company’s website on your label, then please be 
aware that the website becomes labeling under the Federal Insecticide Fungicide and Rodenticide 
Act and is subject to review by the Agency. If the website is false or misleading, the product 
would be misbranded and unlawful to sell or distribute under FIFRA section 12(a)(1)(E). 40 
CFR 156.10(a)(5) list examples of statements EPA may consider false or misleading. In addition, 
regardless of whether a website is referenced on your product’s label, claims made on the 
website may not substantially differ from those claims approved through the registration process. 
Therefore, should the Agency find or if it is brought to our attention that a website contains false 
or misleading statements or claims substantially differing from the EPA approved registration, 
the website will be referred to the EPA’s Office of Enforcement and Compliance. 
A copy of your label stamped “Accepted” is enclosed. Products shipped after 12 months from the 
date of this amendment must bear the new revised label. Your release for shipment of the 
product bearing the amended label constitutes acceptance of these conditions. If these conditions 
are not complied with, the registration will be subject to cancellation in accordance with FIFRA 
section 6. 
Reg Review Label Acceptable v.20151230

Page 2 of 2 
EPA Reg. No. 100-1385 
Decision No. 555241 
If you have any questions about this letter, please contact Srijana Shrestha by phone at 703-305-
6471, or via email at Shrestha.srijana@epa.gov. 
S
incerely, 
L
inda Arrington, Branch Chief 
Risk Management and Implementation Branch 4 
Pesticide Re-Evaluation Division 
Office of Pesticide Programs 
E
nclosure

Flexstar GT 3.5 
Page 1 
[Master Label] 
Flexstar® GT 3.5 
 
Herbicide 
For Control of Certain Weeds in Cotton and Soybeans 
Active Ingredients: 
Sodium Salt of Fomesafen: ..................................................................................... 5.88% 
Glyphosate: ........................................................................................................... 22.40% 
Other Ingredients: 71.72% 
Total: 100.00% 
Flexstar GT 3.5 is formulated as a soluble liquid. 
Flexstar GT 3.5 contains 0.56 pounds of fomesafen and 2.26 pounds of glyphosate expressed as 
acid equivalent per gallon. 
 
KEEP OUT OF REACH OF CHILDREN. 
 
CAUTION 
See additional precautionary statements and directions for use inside booklet. 
EPA Reg. 100-1385 
EPA Est. 
____ gallons 
Net Contents 
GLYPHOSATE GROUP 9 HERBICIDE 
FOMESAFEN GROUP 14 HERBICIDE 
Sep 20, 2019
100-1385

Page 2 
 
 
FIRST AID 
If in eyes x Hold eye open and rinse slowly and gently with water for 15-20 
minutes. 
x Remove contact lenses, if present, after the first 5 minutes, then 
continue rinsing. 
x Call a poison control center or doctor for treatment advice. 
If swallowed x Call a poison control center or doctor immediately for treatment 
advice. 
x Have person sip a glass of water if able to swallow. 
x Do not induce vomiting unless told to by a poison control center 
or doctor. 
x Do not give anything by mouth to an unconscious person. 
If on skin or 
clothing 
x Take off contaminated clothing. 
x Rinse skin immediately with plenty of water for 15-20 minutes. 
x Call a poison control center or doctor for treatment advice. 
If inhaled x Move person to fresh air. 
x If person is not breathing, call 911 or an ambulance, then give 
artificial respiration, preferably mouth-to-mouth, if possible. 
x Call a poison control center or doctor for further treatment 
advice. 
Have the product container or label with you when calling a poison control center or 
doctor or going for treatment. 
HOTLINE NUMBER 
For 24-Hour Medical Emergency Assistance (Human or Animal) 
Or Chemical Emergency Assistance (Spill, Leak, Fire or Accident) 
Call 
1-800-888-8372 
 
 
PRECAUTIONARY STATEMENTS 
 
Hazards to Humans and Domestic Animals 
 
CAUTION 
 
Causes moderate eye irritation. Avoid contact with eyes or clothing. Wash thoroughly with soap and 
water after handling and before eating, drinking, chewing gum, using tobacco, or using the toilet. 
 
Personal Protective Equipment (PPE) 
 
Applicators and other handlers must wear: 
x Long-sleeved shirt and long pants 
x Shoes plus socks 
x Chemical-resistant gloves: barrier laminate, butyl rubber >14 mils, nitrile rubber >14 mils, 
neoprene rubber >14 mils, polyvinyl chloride (PVC) >14 mils, or Viton® >14 mils.

Page 3 
 
 
User Safety Requirements 
 
Follow manufacturer's instructions for cleaning/maintaining PPE. If no such instructions for 
washables exist, use detergent and hot water. Keep and wash PPE separately from other laundry. 
 
Engineering Controls 
 
When handlers use closed systems, enclosed cabs, or aircraft in a manner that meets the 
requirements listed in the Worker Protection Standard (WPS) for agricultural pesticides [40 CFR 
170.240(d)(4-6)], the handler PPE requirements may be reduced or modified as specified in the WPS. 
 
 
User Safety Recommendations 
 
Users should: 
 
x Wash hands thoroughly with soap and water after handling and before eating, 
drinking, chewing gum, using tobacco or using the toilet. 
x Remove clothing/PPE immediately if pesticide gets inside. Then wash thoroughly 
and put on clean clothing. 
x Remove PPE immediately after handling this product. Wash the outside of gloves 
before removing. As soon as possible, wash thoroughly and change into clean 
clothing. 
 
 
Environmental Hazards 
 
Non-target Organism Advisory 
 
This product is toxic to plants and may adversely impact the forage and habitat of non-target 
organisms, including pollinators, in areas adjacent to the treated site. Protect the forage and habitat 
of non-target organisms by following label directions intended to minimize spray drift. 
 
For Terrestrial Uses: Do not apply directly to water, or to areas where surface water is present, or to 
intertidal areas below the mean high water mark. Do not contaminate water when disposing of 
equipment washwater or rinsate. Do not apply when weather conditions favor drift from target area. 
 
Drift and runoff may be hazardous to aquatic organisms in water adjacent to treated areas.

Page 4 
 
 
Groundwater Advisory 
 
Fomesafen is known to leach through soil into groundwater under certain conditions as a result of 
label use. This chemical may leach into groundwater if used in areas where soils are permeable, 
particularly where the water table is shallow. 
 
Surface Water Advisory 
 
This product may impact surface water quality due to spray drift and runoff of rain water. This is 
especially true for poorly draining soils and soils with shallow ground water. This product is classified 
as having high potential for reaching surface water via runoff for several months after application. A 
level, well-maintained vegetative buffer strip between areas to which this product is applied and 
surface water features such as ponds, streams, and springs will reduce the potential loading of 
fomesafen from runoff water and sediment. Runoff of this product will be reduced by avoiding 
applications when rainfall is forecasted to occur within 48 hours. See the manual for “Conservation 
Buffers to Reduce Pesticide Losses” at the following internet address: 
http://www.wsi.nrcs.usda.gov/products/W2Q/pest/core4.html. 
 
Physical and Chemical Hazards 
 
Do not store, mix or apply this product or spray solutions of this product in unlined steel (except 
stainless steel), galvanized steel containers, or sprayer tanks. This product or spray solutions of this 
product will react with these containers and tanks and produce hydrogen gas which may form a highly 
combustible mixture. This gas mixture could flash or explode, causing serious personal injury, if 
ignited by spark, open flame, lighted cigarette, welder torch, or other ignition source. 
 
Spray solutions of this product must be mixed, stored and applied using only stainless steel, 
fiberglass, plastic, or plastic-lined steel containers.

Page 5 
 
 
DIRECTIONS FOR USE 
 
It is a violation of Federal Law to use this product in a manner inconsistent with its labeling. 
 
Do not apply this product in a way that will contact workers or other persons, either directly or through 
drift. Only protected handlers may be in the area during application. For any requirements specific to 
your State or Tribe, consult the agency responsible for pesticide regulation. 
 
 
AGRICULTURAL USE REQUIREMENTS 
 
Use this product only in accordance with its labeling and with the Worker Protection 
Standard, 40 CFR part 170. This Standard contains requirements for the protection of 
agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of 
agricultural pesticides. It contains requirements for training, decontamination, 
notification, and emergency assistance. It also contains specific instructions and 
exceptions pertaining to the statements on this label about personal protective 
equipment (PPE), and restricted-entry interval. The requirements in this box only apply 
to uses of this product that are covered by the Worker Protection Standard. 
 
Do not enter or allow worker entry into treated areas during the restricted-entry 
interval (REI) of 24 hours. 
 
PPE required for early entry to treated areas that is permitted under the Worker 
Protection Standard and that involves contact with anything that has been treated, 
such as plants, soil, or water, is: 
 
x Coveralls 
x Shoes plus socks 
x Chemical-resistant gloves: barrier laminate, butyl rubber >14 mils, nitrile rubber 
>14 mils, neoprene rubber >14 mils, polyvinyl chloride (PVC) >14 mils, or Viton 
>14 mils.

Page 6 
 
 
PRODUCT INFORMATION 
 
Flexstar GT 3.5 may be applied as a preplant or preemergence burndown application in cotton or as 
a postemergence directed application in glyphosate-tolerant (GT) cotton* and as a preplant or 
preemergence burndown in soybeans or as a postemergence over-the-top application in glyphosate-
tolerant (GT) soybeans** to control labeled broadleaf, grass and sedge weeds. 
 
 *Flexstar GT 3.5 may be used on the following glyphosate-tolerant cotton: Roundup Ready Flex 
Cotton, Bollgard II XtendFlex Cotton 
 
**Flexstar GT 3.5 may be used on the following glyphosate-tolerant soybeans: all Roundup Ready 
soybeans including Roundup Ready Soybean, Roundup Ready 2 Yield Soybean, Roundup Ready 
2 Xtend Soybean 
 
Environmental and Agronomic Conditions 
 
Always apply Flexstar GT 3.5 under favorable environmental conditions that promote active weed 
growth. Avoid applying Flexstar GT 3.5 to weeds which are under stress from drought, extreme 
temperatures, excessive water, low humidity, low soil fertility, mechanical or chemical injury as 
reduced weed control and/or increased crop injury may result. 
 
Preplant Surface, Preemergence or Postemergence Applications 
 
Flexstar GT 3.5 will control or partially control certain germinating broadleaf weeds and sedges by soil 
residual activity from either preplant surface, preemergence or postemergence applications that come 
in contact with the soil. Moisture is necessary to activate Flexstar GT 3.5 in soil for residual weed 
control. Dry weather following applications of Flexstar GT 3.5 may reduce effectiveness. When 
adequate moisture is not received within 7 days after a Flexstar GT 3.5 application, weed control may 
be improved by overhead irrigation with at least a ¼ inch of water. 
 
Cultivation 
 
Cultivation prior to postemergence application is not recommended. Weeds may be put under stress 
by cultivation thus reducing weed control. Timely cultivation 2-3 weeks after applying Flexstar GT 3.5 
may assist weed control. 
 
Adjuvants 
 
When an adjuvant is to be used with this product, the use of an adjuvant that meets the standards of 
the Chemical Producers and Distributors Association (CPDA) adjuvant certification program is 
recommended.

Page 7 
 
 
RESISTANT WEED MANAGEMENT 
 
 
 
 
Flexstar GT 3.5 contains the active ingredients glyphosate which inhibits 5-enolpyruvylshikimate-3-
phosphate synthase (EPSPS, Site of Action Group 9) and fomesafen which inhibits the enzyme 
protoporphyrinogen oxidase (PPO or PROTOX, Site of Action Group 14). Some naturally occurring 
weed populations have been identified as resistant to Group 9 and Group 14 herbicides. Selection of 
resistant biotypes, through repeated use of these herbicides or lower than recommended use rates in 
the same field, may result in weed control failures. A resistant biotype may be present where poor 
performance cannot be attributed to adverse environmental conditions or improper application 
methods. 
Contact your local Syngenta representative, retailer, crop advisor or extension agent to determine if 
weeds resistant to modes of action contained in this product are present in your area. If resistant 
biotypes have been reported, use the full labeled rate of this product, apply at the labeled timing, and 
tank-mix with a different mode of action product so there are multiple effective modes of application 
for each suspected resistant weed. 
 
Principles of Herbicide Resistant Weed Management 
Scout and know your field 
• Know weed species present in the field to be treated through scouting and field history. An 
understanding of weed biology is useful in designing a resistance management strategy. 
Ensure the weed management program will control all weeds present. 
• Fields should be scouted prior to application to determine species present and growth stage. 
Always apply this herbicide at the full labeled rate and correct timing for the weeds present in 
the field. 
Utilize non-herbicidal practices to add diversity 
• Use diversified management tactics such as cover crops, mechanical weed control, harvest 
weed seed control, and crop rotation as appropriate. 
 
Use good agronomic practices, start clean and stay clean 
• Use good agronomic practices that enhance crop competitiveness. 
• Plant into weed-free fields utilizing tillage or an effective burndown herbicide for control of 
emerged weeds. 
• Sanitize farm equipment to avoid spreading seed or vegetative propagules prior to leaving 
fields. 
Difficult to control weeds 
• Fields with difficult to control weeds should be planted in rotation with crops that allow the use 
of herbicides with an alternative mode of action or different management practices. 
GLYPHOSATE GROUP 
9 HERBICIDE 
FOMESAFEN GROUP 14 HERBICIDE

Page 8 
 
 
• Difficult to control weeds may require sequential applications, such as a broad spectrum 
preemergence herbicide followed by one or more postemergence herbicide applications. 
Utilize herbicides containing different modes of action effective on the target weeds in 
sequential applications. 
Do not overuse the technology 
• Do not use more than two applications of this or any other herbicide with the same mode of 
action in a single growing season unless mixed with an herbicide with a different mode of 
action which provides overlapping spectrum for the difficult to control weeds. 
Scout and inspect fields following application 
• Prevent an influx of weeds into the field by controlling weeds in field borders. 
• Scout fields after application to verify that the treatment was effective. 
 
• Suspected- herbicide resistant weeds may be identified by these indicators 
• Failure to control a weed species normally controlled by the herbicide at the dose 
applied, especially if control is achieved on adjacent weeds; 
• A spreading patch of non-controlled plants of a particular weed species; and 
• Surviving plants mixed with controlled individuals of the same species. 
• Report non-performance of this product to your Syngenta retailer, Syngenta representative, or 
call 1-866-Syngent (
866-796-4368). If resistance is suspected ensure weed escapes are 
controlled using an herbicide with an effective mode of action and/or use non-chemical means 
to prevent further seed production. 
Prevent weed escapes before, during, and after harvest 
• Do not allow weed escapes to produce seed or vegetative structures such as tubers or stolons 
which contribute to spread and survival. Consider harvest weed seed management and 
control weeds post-harvest to prevent seed production.

Page 9 
 
 
 SPRAY DRIFT MANAGEMENT 
 
SPRAY DRIFT 
Aerial Applications: 
 
x Do not release spray at a height greater than 10 ft above the vegetative canopy, 
unless a greater application height is necessary for pilot safety. 
x For applications prior to the emergence of crops and target weeds, applicators 
are required to use a Coarse or coarser droplet size (ASABE S572.1). 
x For all other applications, applicators are required to use a Medium or coarser 
droplet size (ASABE S572.1). 
x For aerial applications: Do not apply when wind speeds exceed 15 mph at the 
application site. If the wind speed is greater than 10 mph, the boom length must 
be 65% or less of the wingspan for fixed wing aircraft and 75% or less of the rotor 
blade diameter for helicopters. Otherwise, the boom length must be 75% or less 
of the wingspan for fixed wing aircraft and 90% or less of the rotor blade diameter 
for helicopters. Applicators must use ½ swath displacement upwind at the 
downwind edge of the field. 
x Nozzles must be oriented so the spray is directed toward the back of the aircraft. 
x Do not apply when wind speeds exceed 15 miles per hour at the application site. 
x Do not apply during temperature inversions. 
 
 
SPRAY DRIFT 
Ground Boom Applications: 
 
x User must only apply with the nozzle height recommended by the manufacturer, 
but no more than 3 feet above the ground or crop canopy unless making a turf, 
pasture, or rangeland application, in which case applicators may apply with a 
nozzle height no more than 4 feet above the ground. 
x For applications prior to the emergence of crops and target weeds, applicators 
are required to use a Coarse or coarser droplet size (ASABE S572.1). 
x For all other applications, applicators are required to use a Medium or coarser 
droplet size (ASABE S572.1). 
x Do not apply when wind speeds exceed 15 miles per hour at the application site. 
x Do not apply during temperature inversions. 
 
 
SPRAY DRIFT ADVISORIES 
 
THE APPLICATOR IS RESPONSIBLE FOR AVOIDING OFF-SITE SPRAY DRIFT. 
BE AWARE OF NEARBY NON-TARGET SITES AND ENVIRONMENTAL CONDITIONS.

Page 10 
 
 
IMPORTANCE OF DROPLET SIZE 
An effective way to reduce spray drift is to apply large droplets. Use the largest droplets that provide 
target pest control. While applying larger droplets will reduce spray drift, the potential for drift will be 
greater if applications are made improperly or under unfavorable environmental conditions. 
 
Controlling Droplet Size – Ground Boom 
x Volume - Increasing the spray volume so that larger droplets are produced will reduce spray 
drift. Use the highest practical spray volume for the application. If a greater spray volume is 
needed, consider using a nozzle with a higher flow rate. 
x Pressure - Use the lowest spray pressure recommended for the nozzle to produce the target 
spray volume and droplet size. 
x Spray Nozzle - Use a spray nozzle that is designed for the intended application. Consider 
using nozzles designed to reduce drift. 
 
Controlling Droplet Size – Aircraft 
x Adjust Nozzles - Follow nozzle manufacturer’s recommendations for setting up nozzles. 
Generally, to reduce fine droplets, nozzles should be oriented parallel with the airflow in flight. 
 
BOOM HEIGHT – Ground Boom 
Use the lowest boom height that is compatible with the spray nozzles that will provide uniform 
coverage. For ground equipment, the boom should remain level with the crop and have minimal 
bounce. 
 
RELEASE HEIGHT - Aircraft 
Higher release heights increase the potential for spray drift. 
 
SHIELDED SPRAYERS 
Shielding the boom or individual nozzles can reduce spray drift. Consider using shielded sprayers. 
Verify that the shields are not interfering with the uniform deposition of the spray on the target area. 
 
TEMPERATURE AND HUMIDITY 
When making applications in hot and dry conditions, use larger droplets to reduce effects of 
evaporation. 
 
TEMPERATURE INVERSIONS 
Drift potential is high during a temperature inversion. Temperature inversions are characterized by 
increasing temperature with altitude and are common on nights with limited cloud cover and light to 
no wind. The presence of an inversion can be indicated by ground fog or by the movement of smoke 
from a ground source or an aircraft smoke generator. Smoke that layers and moves laterally in a 
concentrated cloud (under low wind conditions) indicates an inversion, while smoke that moves 
upward and rapidly dissipates indicates good vertical air mixing. Avoid applications during 
temperature inversions.

Page 11 
 
 
WIND 
Drift potential generally increases with wind speed. AVOID APPLICATIONS DURING GUSTY WIND 
CONDITIONS. 
 
Applicators need to be familiar with local wind patterns and terrain that could affect spray drift. 
 
APPLICATION DIRECTIONS 
 
Spray Adjuvants 
 
Flexstar GT 3.5 is specifically formulated with the ISOLINK™ Technology II that minimizes the need 
for additional spray adjuvants. Under certain conditions, burndown and postemergence activity may 
be improved by adding one or more of the following spray adjuvants: 
 
Ammonium Sulfate (AMS) at 8.5 to 17 lb/100 gallons of water should be added in areas where 
commonly used with glyphosate-containing products. Liquid formulations of AMS may be used at an 
equivalent rate. 
 
Urea Ammonium Nitrate (UAN) (28-32% liquid nitrogen solution) may be added at 1-2.5% v/v (1-2.5 
gallons/100 gallons) of finished spray volume. If AMS is being added, UAN is generally not required. 
UAN can improve weed control but may reduce crop tolerance. 
 
One of the following spray adjuvants can be added for difficult to control weeds or under 
adverse environmental conditions: 
 
Crop Oil Concentrate (COC) or Methylated Seed Oil (MSO): Use a nonphytotoxic COC or MSO 
containing 15-20% approved emulsifier at 0.5-1% v/v (2-4 quarts/100 gallons) of finished spray 
volume. COC or MSO can improve weed control but may reduce crop tolerance. 
 
Nonionic Surfactant (NIS): Use NIS containing at least 80% active ingredient at 0.25-0.5% v/v (1-2 
quarts/100 gallons) of finished spray volume. 
 
Recommended Tank Mixing Order 
 
1. Fill the spray tank with ½ to Ҁ the required amount of water and begin agitation. 
2. Add AMS (if used). 
3. Add dry pesticide formulations (WP, DF, etc.). 
4. Add liquid pesticide formulations (EC, SC, etc.). 
5. Add Flexstar GT 3.5. 
6. Add COC, MSO or NIS (if used). 
7. Add the remaining water and maintain agitation throughout the spray operation. 
 
Be sure to allow each tank-mix component to fully disperse before adding the next.

Page 12 
 
 
Tank-Mix Compatibility Test 
 
A jar test is recommended prior to tank mixing to ensure compatibility of Flexstar GT 3.5 with mixture 
partners. 
 
x Conduct a jar test using a 1 pt to 1 qt container with lid by adding water or other intended carrier 
such as a liquid fertilizer to the jar. 
x Next, add the appropriate amount of pesticide(s) or tank-mix partner(s) in their relative proportions 
based on label rates. Add tank-mix components separately in the order described in the tank-
mixing section. After each addition, shake or stir gently to thoroughly mix. 
x After all ingredients have been added, put the lid on the jar, tighten and invert the jar 10 times to 
mix. 
x After mixing, let the mixture stand 15 – 30 minutes and then examine for signs of incompatibility 
such as obvious separation, large flakes, precipitates, gels or heavy oily film on the jar. 
x If the mixture remains mixed or can be remixed readily, it is physically compatible and can be 
used. 
x If the mixture is incompatible, repeat the test using a compatibility agent at the label rate. Or, if 
applicable, slurry dry formulations in water before adding to the jar. If incompatibility is still 
observed after following these procedures, do not use the mixture. 
x After compatibility testing is complete, dispose of any pesticide wastes in accordance with the 
storage and disposal section of this label. 
 
APPLICATION INSTRUCTIONS 
 
Ground Application 
 
Use sufficient spray volume and pressure to ensure complete coverage of the target. A spray volume 
of 15-20 gallons per acre and 30-60 psi at the nozzle tip is recommended. When foliage is dense, use 
a minimum of 20 gallons per acre to ensure adequate coverage. 
 
The use of flat fan nozzles will result in the most effective postemergence application of Flexstar GT 
3.5. Use nozzles that are set up to deliver medium quality spray (ASAE Standard S-572). 
 
Aerial Application 
 
Use sufficient spray volume and pressure to ensure complete coverage of the target. A minimum of 5 
gallons per acre of spray mixture should be applied with a maximum of 40 psi pressure. When 
foliage is dense, use a minimum of 10 gallons per acre to ensure coverage of weed foliage.

Page 13 
 
 
 
RESTRICTIONS 
 
x DO NOT APPLY THIS PRODUCT THROUGH ANY TYPE OF IRRIGATION SYSTEM. 
 
x DO NOT USE FLOOD TYPE OR OTHER SPRAY NOZZLES WHICH DELIVER LARGE 
DROPLET SPRAYS. 
 
x A maximum of 5.3 pt of Flexstar GT 3.5 (or a maximum of 0.375 lb ai/A of fomesafen from any 
product containing fomesafen) may be applied per acre per year in Region 1 (see Regional Use 
Map). 
 
x A maximum of 5.3 pt of Flexstar GT 3.5 (or a maximum of 0.375 lb ai/A of fomesafen from any 
product containing fomesafen) may be applied per acre in ALTERNATE years in Region 2 (see 
Regional Use Map). 
 
x A maximum of 4.5 pt of Flexstar GT 3.5 (or a maximum of 0.315 lb ai/A of fomesafen from any 
product containing fomesafen) may be applied per acre in ALTERNATE years in Region 3 (see 
Regional Use Map). 
 
x A maximum of 3.5 pt of Flexstar GT 3.5 (or a maximum of 0.25 lb ai/A of fomesafen from any 
product containing fomesafen) may be applied per acre in ALTERNATE years in Region 4 (see 
Regional Use Map). 
 
x A maximum of 3.5 pt of Flexstar GT 3.5 (or a maximum of 0.25 lb ai/A of fomesafen from any 
product containing fomesafen) may be applied per acre in ALTERNATE years in Region 4a 
(see Regional Use Map). Apply only to soybeans in Region 4a. Do not make a Flexstar GT 3.5 
application later than June 20
th. Cumulative rainfall plus overhead irrigation must total 15 inches 
from the period of Flexstar GT 3.5 application to soybean crop maturity to allow planting of 
rotational crops listed in this label (refer to Rotational Crop Restrictions section). If the soybean 
crop is lost or the required cumulative rainfall plus irrigation is not received as outlined above, 
plant only soybeans the following growing season. 
 
x A maximum of 2.68 pt of Flexstar GT 3.5 (or a maximum of 0.1875 lb ai/A of fomesafen from 
any product containing fomesafen) may be applied per acre in ALTERNATE years in Region 5 
(see Regional Use Map).

Page 14 
 
 
PRECAUTIONS 
 
x Thoroughly clean the spray system with water and a commercial tank cleaner before and after 
each use. 
 
x Tank mixes of Flexstar GT 3.5 with other pesticides, fertilizers or any other additives except as 
specified on this label or other Syngenta labeling or recommendations made by Syngenta Crop 
Protection, may result in tank-mix incompatibility, unsatisfactory performance or unacceptable 
crop injury. 
 
x Avoid overlapping spray swaths, as injury may occur in crop or to rotational crops. 
 
x Heavy rainfall or irrigation shortly after application may reduce performance. 
 
x Optimum coverage will occur when the ground speed does not exceed 10 mph during application. 
 
x Do not apply when wind velocity exceeds 15 mph. 
 
x Do not spray if conditions of thermal inversion exist, or if wind direction and speed may cause 
spray to drift onto adjacent nontarget areas. Drift minimization is the responsibility of the 
applicator. Consult with local and State agricultural authorities for information on avoiding or 
minimizing spray drift. 
 
x Flexstar GT 3.5 is not volatile and cannot move as vapor after application onto nontarget 
vegetation. 
 
x Severe damage or destruction may be caused by contact of Flexstar GT 3.5 to any desirable crop 
or plant to which treatment is not intended. 
 
x Spray solutions of Flexstar GT 3.5 must be mixed, stored and applied using only plastic, plastic-
lined steel, stainless steel, or fiberglass containers. Concentrate must not be stored in galvanized, 
carbon steel, aluminum or unlined steel containers. 
 
x The use of deposition (drift control) agents that impact droplet size and coverage may reduce 
weed control.

Page 15 
 
 
Replanting 
If replanting is necessary in fields previously treated with Flexstar GT 3.5, the field may be replanted 
to cotton, dry beans, potatoes, snap beans or soybeans. 
 
RESTRICTION: DO NOT APPLY A SECOND APPLICATION OF FLEXSTAR GT 3.5 OR OTHER 
FOMESAFEN-CONTAINING PRODUCT AS CROP INJURY OR ILLEGAL RESIDUES MAY 
OCCUR IN HARVESTED CROPS. 
 If tank-mix combinations were used, refer to product labels for any additional replanting instructions. 
 
The following rotational crops may be planted after applying Flexstar GT 3.5 at recommended rates: 
 
Rotational Crops 
Planting Time From Last 
Flexstar GT 3.5 Application 
Bean, Dry 
Bean, Snap 
Cotton 
Potato 
Soybean 
Soybean, Succulent (edamame) 
0 months 
Bean, Lima 
Pea, Succulent 
Small Grains including Wheat, Barley, Rye 
4 months 
Corn, Field 
Corn, Seed 
Corn, Sweet
5 
Peanut 
Pepper (transplanted)
1 
Popcorn4 
Pumpkin2 
Rice 
Tomato (transplanted)
1 
Watermelon2 
10 months 
Bean, Succulent (other than edamame, snap bean and 
 lima bean) 
Cantaloupe
2 
Cucumber2 
Edible-podded beans and peas not otherwise specified 
 in this table 
Eggplant 
Pea, Dry 
Pepper (direct-seeded) 
Squash
2 
Sunflower 
Sweet Potato 
Tomato (direct-seeded) 
12 months 
Sorghum3 18 months 
All other crops not listed above 18 months 
1 4 months in Region 1 
2 8 months in Region 1

Page 16 
 
 
3 10 months in Region 1 
4 12 months in the states of Ohio, Kentucky, Illinois, Indiana, Iowa, and Region 4 and 
 4a when applied at rates of 3.5 pints per acre or more 
5 18 months in the states of Connecticut, Maine, Massachusetts, New Hampshire, New 
 York, Rhode Island, Vermont and Region 5 
 
Restriction: Do not graze rotated small grain crops or harvest forage or straw for livestock. 
 
 
Cover Crops 
 
A cover crop can be an important tool for the overall farm cropping system. Cover crops are planted 
for conservation purposes, soil erosion control, soil health improvement, water quality improvement 
and weed management. A cover crop can be a single crop or a combination of crops, including 
grasses and/or broadleaf crops. After harvest of a Flexstar GT 3.5 treated crop, planting of a cover 
crop is allowed provided the cover crop is not grazed or fed to livestock nor harvested for food. 
Terminate the cover crop through natural causes such as frost or intentional termination by herbicide 
application, crimping, rolling, tillage or cutting. All possible cover crops or cover crop combinations 
have not been tested for tolerance to this product. Before planting the cover crop, determine the level 
of tolerance for the intended cover crops by conducting a field bioassay. Refer to the Field Bioassay 
for Cover Crops section for instructions on how to conduct a field bioassay. 
 
Field Bioassay for Cover Crops 
 
A field bioassay is a method of determining if herbicide residues are present in the soil at 
concentrations high enough to adversely affect crop growth. Conduct the field bioassay by planting 
several strips of the desired cover crop across the field which has been previously treated with 
Flexstar GT 3.5. Plant the cover crop strips perpendicular to the direction of the product application. 
Locate the strips so that all the different field conditions are encountered, including differences in field 
terrain, soil texture, organic matter, pH, and drainage. If the cover crop does not show adverse effects 
such as crop injury and/or stand reduction, the field can be planted to this cover crop. If injury and/or 
stand reduction are visible, wait two to four weeks for further herbicide degradation to occur and 
repeat the bioassay. Alternatively, select a different cover crop and repeat the bioassay. Only plant 
cover crops that show acceptable tolerance in the field bioassay.

Page 17 
 
 
USE RATES AND WEEDS CONTROLLED 
 
REFER TO MAP FOR DEFINITION OF SPECIFIED 
GEOGRAPHIC REGIONS 
 
FLEXSTAR GT 3.5 REGIONAL USE MAP 
 
 
 
 
Refer to crop specific application directions in this label for specific application information for each 
crop in each region including the maximum yearly application rate, maximum number of applications, 
pre-harvest and retreatment interval.

Page 18 
 
 
 
REGION 1 
(Maximum Rate 5.3 pt/A per year) 
 
 
 
 
Includes the following states or portion of states where Flexstar GT 3.5 may be applied: 
 
 
 
 
 
 
Region 1 
Alabama All areas. 
Arkansas All areas. 
Florida All areas except for Miami-Dade County. 
Georgia All areas. 
Louisiana All areas. 
Mississippi All areas. 
Missouri Counties of Bollinger, Butler, Cape Giradeau, Dunklin, Madison, 
Mississippi, New Madrid, Pemiscot, Perry, Ripley, Scott, Stoddard and 
Wayne. 
North Carolina All areas. 
Oklahoma All areas East of U.S. Highway 75 and East of Indian Nation Parkway. 
South Carolina All areas. 
Tennessee All areas. 
Texas All areas East of U.S. Highway 77 to State Road 239, including all of 
Calhoun County. 
Refer to crop specific application directions in this label for specific application information for each crop in 
each region including the maximum yearly application rate, maximum number of applications, pre-harvest 
interval and retreatment interval.

Page 19 
 
 
 
REGION 2 
(Maximum Rate 5.3 pt/A, Alternate Years) 
 
 
 
 
Includes the following states or portion of states where Flexstar GT 3.5 may be applied: 
 
 
 
 
Region 2 
Delaware All areas. 
Illinois All areas South of Interstate 70. 
Indiana All areas South of Interstate 70. 
Kentucky All areas. 
Maryland All areas. 
Ohio All areas South of Interstate 70. 
Pennsylvania All areas South of Interstate 80 to the intersection of U.S. Highway 15 and 
East of U.S. Highway 15 and U.S. Highway 522. 
Virginia All areas. 
West Virginia All areas. 
Refer to crop specific application directions in this label for specific application information for each crop in 
each region including the maximum yearly application rate, maximum number of applications, pre-harvest 
interval and retreatment interval.

Page 20 
 
 
REGION 3 
(Maximum Rate 4.5 pt/A, Alternate Years) 
 
 
 
Includes the following states or portion of states where Flexstar GT 3.5 may be applied: 
 
 
 
 
 
 
 
Region 3 
Connecticut All areas. 
Illinois All areas North of Interstate 70. 
Indiana All areas North of Interstate 70. 
Iowa All areas. 
Maine All areas. 
Massachusetts All areas. 
Missouri All counties except for those listed in Region 1. 
Ohio All areas North of Interstate 70. 
New 
Hampshire 
All areas. 
New Jersey All areas. 
New York All areas. 
Pennsylvania All areas except those listed in Region 2. 
Rhode Island All areas. 
Vermont All areas. 
Wisconsin All areas South of U.S. Highway 18 between Prairie Du Chien and 
Madison, and South of Interstate 94 between Madison and Milwaukee. 
Refer to crop specific application directions in this label for specific application information for each crop in 
each region including the maximum yearly application rate, maximum number of applications, pre-harvest 
interval and retreatment interval.

Page 21 
 
 
REGION 4 
(Maximum Rate 3.5 pt/A, Alternate Years) 
 
 
 
Includes the following states or portion of states where Flexstar GT 3.5 may be applied: 
 
 
 
 
 
 
 
Region 4 
Kansas All counties east of or intersected by U.S. Highway 281. 
Michigan Southern Peninsula. 
Minnesota All areas south of Interstate 94. 
Nebraska All counties east of or intersected by U.S. Highway 281. 
North Dakota All areas east of Interstate 29 from Fargo south to the South Dakota state 
line. 
South Dakota All areas east of Interstate 29 from the North Dakota state line to 
Watertown, all areas east of Highway 81 from Watertown to Madison and 
all areas east and south of State Road 34 and U.S. Highway 281 to the 
Nebraska state line. 
Wisconsin All areas south of Interstate 94 (except those in Region 3) from Minnesota 
state line to Eau Claire and south of U.S. Highway 29 from Eau Claire to 
Green Bay plus Barron, Burnett, Chippewa, Clark, Door, Dunn, Eau Claire, 
Langlade, Lincoln, Kewaunee, Marathon, Marinette, Menominee, Oconto, 
Polk, Price, Rusk, Sawyer, Shawano, St. Croix, Taylor, and Washburn 
counties. The following counties are excluded: Adams, Marquette, 
Portage, Waupaca, Waushara and Wood. 
Refer to crop specific application directions in this label for specific application information for each crop in 
each region including the maximum yearly application rate, maximum number of applications, pre-harvest 
interval and retreatment interval.

Page 22 
 
 
 
REGION 4a 
(Maximum Rate 3.5 pt/A, Alternate Years*) 
 
 
 
 
 
 
Includes the following portions of states where Flexstar GT 3.5 may be applied: 
Region 
4a 
Kansas All areas west of U.S. Highway 281 to the Colorado state line. 
Nebraska All areas that intersect west of U.S. Highway 281 and east of U.S. Highway 
83. 
Refer to crop specific application directions in this label for specific application information for each crop in 
each region including the maximum yearly application rate, maximum number of applications, pre-harvest 
interval and retreatment interval. 
 
*Note: Refer to the Restrictions section for additional requirements that must be followed to 
use Flexstar GT 3.5 in Region 4a.

Page 23 
 
 
 
REGION 5 
(Maximum Rate 2.68 pt/A, Alternate Years) 
 
 
 
 
 
 
 
Includes the following states or portion of states where Flexstar GT 3.5 may be applied: 
 
 
Region 5 
Minnesota All areas south of U.S. Highway 2 (except those areas in Region 4), plus 
Betrami, Clearwater, Lake of the Woods, Kittson, Marshall, Pennington, 
Polk, Red Lake, and Roseau. 
North Dakota All areas east of U.S. Highway 281, except those areas in Region 4. 
South Dakota All areas east of U.S. Highway 281, except those areas in Region 4. 
Refer to crop specific application directions in this label for specific application information for each crop in 
each region including the maximum yearly application rate, maximum number of applications, pre-harvest 
interval and retreatment interval.

Page 24 
 
 
 
WEEDS CONTROLLED 
 
Table 1. Weeds controlled or partially controlled* by preplant surface or preemergence 
application of Flexstar GT 3.5 at 3.5 to 5.3 pt/A
1. 
 
Broadleaf Weeds Controlled Soil Texture
Organic 
Matter 
Amaranth, Palmer Amaranthus palmeri All soil types Up to 5% 
Croton, tropic2 Croton glandulosus 
Eclipta Eclipta prostrata 
Galinsoga species Galinsoga spp. 
Lambsquarters, common Chenopodium album 
Morningglory, smallflower Jacquemontia tamnifolia 
Nightshade, black Solanum nigrum 
Nightshade, eastern black Solanum ptychanthum 
Pigweed, redroot Amaranthus retroflexus 
Pigweed, smooth Amaranthus hybridus 
Poinsettia, wild Euphorbia heterophylla 
Purslane, common Portulaca oleracea 
Ragweed, common2 Ambrosia artemisiifolia 
Sida, prickly2 Sida spinosa 
Starbur, bristly Acanthospermum hispidum 
Broadleaf Weeds Partially Controlled* 
Anoda, spurred Anoda cristata 
Cocklebur, common Xanthium strumarium 
Morningglory, entireleaf Ipomoea hederacea var. 
integriuscula 
 
Morningglory, ivyleaf Ipomoea hederacea 
Morningglory, pitted (small white) Ipomoea lacunosa 
Morningglory, red (scarlet) Ipomoea coccinea 
Morningglory, tall (common) Ipomoea purpurea 
Nightshade, hairy Solanum physalifolium 
Ragweed, giant Ambrosia trifida 
Waterhemp species Amaranthus spp. 
Sedges Partially Controlled* 
Nutsedge, yellow Cyperus esculentus 
 
*Partial control means significant activity, but not always at a level considered acceptable for 
commercial weed control. 
1Use the higher end of the rate range when heavy weed populations are anticipated. 
2Rates less than 5.3 pt/A will provide only partial control of this weed.

Flexstar GT 3.5 
Page 25 
 
 
Table 2. Broadleaf weeds controlled by postemergence application of Flexstar GT 3.5 
 
 
 Flexstar GT 3.5 Rate (pt/A) 
Maximum Growth Stage Controlled At 
Broadleaf Weeds 
Controlled1 Scientific Name 
3.5 pt/A 
Maximum 
Height (inches) 
4.5 pt/A 
Maximum Height 
(inches) 
5.3 pt/A 
Maximum 
Height (inches) 
Amaranth, Palmer 
(glyphosate susceptible) 
Amaranthus palmeri 4 4 6 
Amaranth, Palmer 
(glyphosate resistant)1 
Amaranthus palmeri 1 2 3 
Amaranth, spiny Amaranthus 
spinosus 
2 2 4 
Anoda, spurred Anoda cristata 4 6 8 
Buttercup species3 Ranunculus spp. 6 8 10 
Carpetweed Mollugo verticillata 6" Diameter Multi-leaf 
6" Diameter 
Unlimited Size 
Chickweed, common Stellaria media 6 8 10 
Chickweed, mouseear Cerastium fontanum 
ssp. vulgare 
6 8 10 
Citronmelon Citrullus lanatus 2 4 6 
Cocklebur, common Xanthium 
strumarium 
4 6 8 
Copperleaf, 
hophornbeam 
Acalypha ostryifolia 2 2 4 
Copperleaf, Virginia Acalypha virginica 2 2 4 
Crotalaria, showy Crotalaria 
spectabilis 
4 6 8 
Croton, tropic Croton glandulosus 2 4 6 
Cucumber, volunteer Cucumis sativas 2 4 6 
Deadnettle, purple Lamium purpureum 4 6 8 
Eclipta Eclipta prostrata 6 8 10 
Eveningprimrose, cutleaf Oenothera laciniata 4 6 8 
Groundcherry, cutleaf Physalis angulata 4 6 6 
Henbit Lamium 
amplexicaule 
4 6 8 
Jimsonweed Datura stramonium 4 6 8 
Lambsquarters, common Chenopodium album 4 8 10 
Morningglory, 
cypressvine 
Ipomoea quamoclit 4 4 6 
Morningglory, entireleaf 
var. 
Ipomoea hederacea 
var. integriuscula 
3 3 4 
Morningglory, ivyleaf Ipomoea hederacea 3 3 4 
Morningglory, purple 
moonflower 
Ipomoea turbinata 3 4 4 
Morningglory, red 
(scarlet) 
Ipomoea coccinea 3 3 4 
Morningglory, 
smallflower 
Jacquemontia 
tamnifolia 
3 3 4

Page 26 
 
 
 
 Flexstar GT 3.5 Rate (pt/A) 
Maximum Growth Stage Controlled At 
Broadleaf Weeds 
Controlled1 Scientific Name 
3.5 pt/A 
Maximum 
Height (inches) 
4.5 pt/A 
Maximum Height 
(inches) 
5.3 pt/A 
Maximum 
Height (inches) 
Morningglory, pitted 
(Small white) 
Ipomoea lacunosa 4 4 4 
Morningglory, tall 
(common) 
Ipomoea purpurea 3 3 4 
Morningglory, palmleaf 
(willowleaf) 
Ipomoea wrightii 3 3 4 
Mustard, wild Sinapis arvensis 6 8 10 
Nightshade, black Solanum nigrum 4 6 8 
Pigweed, redroot Amaranthus 
retroflexus 
4 6 6 
Pigweed, smooth Amaranthus 
hybridus 
4 4 6 
Poinsettia, wild Euphorbia 
heterophylla 
4 6 8 
Purslane, common Portulaca oleracea Multi-Leaf 
4" Diameter 
Multi-Leaf 
6" Diameter 
Multi-Leaf 
8" Diameter 
Pusley, Florida Richardia scabra 4 6 8 
Ragweed, common 
(glyphosate susceptible) 
Ambrosia 
artemisiifolia 
4 5 6 
Ragweed, common 
(glyphosate resistant)1 
Ambrosia 
artemisiifolia 
2 4 5 
Ragweed, giant 
(glyphosate susceptible) 
Ambrosia trifida 4 6 8 
Ragweed, giant 
(glyphosate resistant)1,2 
Ambrosia trifida 2 2 4 
Redweed Melochia 
corchorifolia 
4 6 8 
Sesbania, hemp Sesbania exaltata 6 8 10 
Shepherdspurse Capsella bursa-
pastoris 
6 8 10 
Sicklepod Senna obtusifolia 2 3 4 
Sida, prickly Sida spinosa 2 3 4 
Smartweed, ladysthumb Polygonum 
persicaria 
4 6 8 
Smartweed, 
Pennsylvania 
Polygonum 
pennsylvanicum
4 6 8 
Spurge, prostrate Chamaesyce 
humistrata 
4 6 8 
Spurge, spotted Chamaesyce 
maculata 
4 6 8 
Starbur, bristly Acanthospermum 
hispidum 
4 6 8 
Sunflower, common Helianthus annuus 4 6 8 
Velvetleaf Abutilon theophrasti 4 6 8 
Venice mallow Hibiscus trionum 4 4 6

Page 27 
 
 
 
 Flexstar GT 3.5 Rate (pt/A) 
Maximum Growth Stage Controlled At 
Broadleaf Weeds 
Controlled1 Scientific Name 
3.5 pt/A 
Maximum 
Height (inches) 
4.5 pt/A 
Maximum Height 
(inches) 
5.3 pt/A 
Maximum 
Height (inches) 
Waterhemp species 
(glyphosate susceptible) 
Amaranthus spp. 2 4 6 
Waterhemp species 
(glyphosate resistant)1 
Amaranthus spp. 2 3 4 
Yellow rocket Barbarea vulgaris 6 8 10 
 
*Partial control means significant activity, but not always at a level considered acceptable for commercial weed 
control. 
1Weed biotypes that have multiple resistances to both glyphosate and protoporphyrinogen oxidase inhibitor 
herbicides, will not be controlled by Flexstar GT 3.5 - see your local Syngenta representative and/or state 
university extension recommendations for control programs. 
2Partial control* of glyphosate resistant giant ragweed - see your local Syngenta representative and/or state 
university extension recommendations for control programs. 
3Control will be reduced at the button stage.

Flexstar GT 3.5 
Page 28 
 
 
Table 3. Grasses controlled by postemergence application of Flexstar GT 3.5 
 
 
Flexstar GT 3.5Rate (pt/A) 
Maximum Growth Stage Controlled At 
Grass Weeds 
Controlled1 Scientific Name 
3.5 pt/A 
Maximum 
Height 
(inches) 
4.5 pt/A 
Maximum 
Height 
(inches) 
5.3 pt/A 
Maximum 
Height 
(inches) 
Barley, volunteer Hordeum vulgare 24 
Barnyardgrass Echinochloa crus-galli 6 10 12 
Bluegrass, annual Poa annua 12 
Corn, volunteer 
(glyphosate 
susceptible) 
Zea mays 24 
Crabgrass species Digitaria spp. 12 
Foxtail species Setaria spp. 18 
Goosegrass Eleusine indica 6 8 12 
Johnsongrass, 
seedling1 Sorghum halepense 
12 18 
Oats, volunteer Avena sativa 18 
Oats, wild Avena fatua 18 
Panicum, browntop Panicum fasciculatum 10 18 
Panicum, fall Panicum 
dichotomiflorum 
6 10 
Panicum, Texas Panicum texanum 10 18 
Red Rice Oryza sativa 3 
Rye, volunteer Secale cereale 12 18 
Ryegrass, Italian 
(annual)1 
Lolium multiflorum 8 10 
Shattercane Sorghum bicolor 12 16 
Sprangletop species Leptochloa spp. 18 
Signalgrass, 
broadleaf Brachiaria platyphylla 
8 10 
Wheat, volunteer Triticum aestivum 18 
Wild proso millet Panicum miliaceum 12 16 
Witchgrass Panicum capillare 12 
Woolly cupgrass Eriochloa villosa 12 
 
1Flexstar GT 3.5 will not control glyphosate-resistant seedling johnsongrass and Italian ryegrass 
biotypes or other glyphosate resistant grass species.

Flexstar GT 3.5 
Page 29 
 
COTTON 
 
Burndown and Residual Weed Control Applications 
 
Flexstar GT 3.5 can provide burndown of emerged weeds and residual control of certain 
germinating broadleaf weeds and sedges in cotton. 
 
Application to Coarse-Textured Soils 
 
Apply Flexstar GT 3.5 from 3.5 to 5.3 pt/A as preplant surface or preemergence 
application to coarse-textured soils (sandy loam, loamy sand, sandy 
clay loam) only. 
 
Refer to Table 1 for use rates and weeds controlled by preplant surface or 
preemergence applications and Tables 2 and 3 for use rates, weed growth stages and 
weeds controlled by postemergence applications. 
 
Application to Medium or Fine-Textured Soils 
 
Apply Flexstar GT 3.5 at 3.5 pt/A as a preplant surface application to medium or fine-
textured soils (i.e., soil types heavier than coarse-textured soils) up to 
21 days prior to planting cotton. Apply after the last tillage operation is completed. 
 
Refer to Table 1 for weeds controlled by preplant surface applications and Tables 2 and 
3 for weed growth stages and weeds controlled by postemergence applications. 
 
Do not exceed 3.5 pt/A of Flexstar GT 3.5 on medium or fine-textured soils. Also, to 
avoid severe crop injury, the following use directions must be followed when 
applications are made to medium or fine-textured soils: 
 
x After Flexstar GT 3.5 application, a minimum of 0.5 inch of rainfall or overhead 
irrigation must occur before planting cotton. 
x Cotton must be planted at least 0.75 inch in depth. 
x Avoid overlapping spray swaths. 
x Do not disturb or re-work the seedbed following application. 
 
The use of an in-furrow or seed applied fungicide will generally assist with seedling 
establishment and development. 
 
Use Directions for Burndown and Residual Weed Control Applications 
 
Emerged weeds must have thorough spray coverage for effective control. Refer to the 
Spray Adjuvants section for directions on spray adjuvants for postemergence weed 
control.

Page 30 
 
 
Moisture is necessary to activate Flexstar GT 3.5 in soil for residual weed control. Dry 
weather following application of Flexstar GT 3.5 may reduce residual activity. When 
adequate moisture is not received within 7 days after a Flexstar GT 3.5 application, 
residual weed control may be improved with at least a ¼ inch of overhead irrigation. 
 
Cotton plants are tolerant to Flexstar GT 3.5 when applied at specified rates and 
application use directions. Some crinkling or spotting of cotton foliage or stunting may 
occur but cotton plants normally outgrow these effects and develop normally. 
 
Tank Mixes for Burndown and Residual Weed Control Applications 
 
Flexstar GT 3.5 can be applied in a tank mix with the following products: Caparol®, 
Cotoran®, Dicamba, Direx®, Glyphosate products (such as Roundup® brands), 
Karmex®, Prowl® H
2O, Solicam®, and Staple®. 
 
It is the pesticide user’s responsibility to ensure that all products are registered for the 
intended use. Read and follow the applicable restrictions and limitations and directions 
for use on all product labels involved in tank mixing. Users must follow the most 
restrictive directions for use and precautionary statements of each product in the tank 
mixture. 
 
Post-Directed Application in Roundup Ready Flex Cotton 
 
Apply Flexstar GT 3.5 in emerged Roundup Ready Flex cotton as a post-directed 
treatment using precision post-directed, hooded or shielded application equipment to 
provide complete coverage of emerged weeds. Apply Flexstar GT 3.5 at 3.5 pt/A in a 
minimum of 15 gallons spray solution per acre. Applications may be made broadcast or 
banded. Post-directed applications of Flexstar GT 3.5 will provide contact control of 
labeled weeds and residual preemergence control of labeled weeds (once activated by 
rainfall or irrigation). Refer to Table 1 for weeds controlled or partially controlled through 
residual activity and Tables 2-3 for weeds controlled by postemergence activity. Do not 
exceed 3.5 pt/A as a post-directed application in Roundup Ready Flex cotton. 
 
Cotton foliage is not tolerant to Flexstar GT 3.5 applications. Avoid contact to cotton 
foliage as unacceptable injury will occur. Calibrate application equipment (spray 
pressure, nozzle type and configuration, and orifice size) to avoid fine spray droplets 
contacting green cotton stems and foliage. 
 
Post-Directed Application Timing in Roundup Ready Flex Cotton 
 
Flexstar GT 3.5 may be applied as a post-directed application to Roundup Ready Flex 
cotton when cotton is at least 6 inches in height through layby. Keep all post-directed 
applications from contacting any green non-barked parts of the cotton plant or foliage as 
unacceptable injury will occur. Follow the application timing recommendations below for 
post-directed applications in Roundup Ready Flex cotton.

Page 31 
 
 
Shielded and Hooded Applications 
 
Make a precision post-directed Flexstar GT 3.5 application to the base of the 
cotton plant avoiding contact with the cotton stem or foliage when cotton is at 
least 6 inches in height to avoid cotton injury. Use only hooded or shielded spray 
equipment to apply Flexstar GT 3.5 in cotton that is 6 inches in height. Adjust 
nozzles to provide full coverage of emerged target weeds. 
 
Layby Applications 
 
Make a post-directed Flexstar GT 3.5 application to the base of the cotton plant 
avoiding contact with any non-barked portion of the cotton plant or foliage. Use 
precision post-directed equipment or hooded or shielded sprayers on cotton that 
has developed a minimum of 4 inches of brown bark through layby. Application 
equipment should be configured to provide full coverage of emerged target 
weeds. 
 
Tank Mixes for Post-Directed Applications 
 
Flexstar GT 3.5 can be applied in a tank mix with most cotton herbicides which are 
labeled for post-directed, hooded or shielded applications. Refer to individual product 
labels for precautionary statements, restrictions, rates and a list of weeds controlled. 
 
Use Restrictions - Cotton 
 
Refer to Flexstar GT 3.5 Regional Use Map for the maximum rate of Flexstar GT 3.5 
(or other fomesafen containing products) that may be applied in each geographic 
region. 
 
Do not apply more than the maximum rate and number of applications of Flexstar GT 
3.5 to cotton in each geographic region (refer to the Flexstar GT 3.5 Regional Use 
Map) specified in the following table. 
 
x DO NOT apply Flexstar GT 3.5 over the top of cotton as plant death will occur. 
x Do not exceed 5.3 pints of Flexstar GT 3.5 per acre in any one year and also adhere 
to the maximum rate that may be applied in each geographic region (refer to the 
Flexstar GT 3.5 Regional Use Map). 
x Do not exceed 3.5 pints of Flexstar GT 3.5 per acre as a preplant surface application 
to medium or fine-textured soil. 
x Do not exceed 3.5 pints of Flexstar GT 3.5 per acre as a post-directed application.

Page 32 
 
 
Use Restrictions for Cotton 
Region Soil Texture 
Maximum Single 
Application 
Flexstar GT 3.5 Rate 
(pt/A) 
Maximum Number 
Applications 
Minimum 
PHI (days) 
1 
Coarse 5.3 
1 per year 70 
Medium to Fine 3.5 
2 
Coarse 5.3 1 every other year 
70 
Medium to Fine 3.5 
3 
Coarse 4.5 1 every other year 
70 
Medium to Fine 3.5 
4 
Coarse 
3.5 
1 every other year 
70 
Medium to Fine 
4a 
 
Not allowed 
 
 
5 
 
Not allowed 
 
 
 
SOYBEANS 
 
Burndown and Residual Weed Control Applications - Glyphosate-Tolerant and 
Non-Glyphosate-Tolerant Soybeans 
 
Flexstar GT 3.5 can provide burndown of emerged weeds and residual control of certain 
germinating broadleaf weeds and sedges from either a preplant surface or 
preemergence application in soybeans. 
 
Refer to Table 1 for rates and weeds controlled by preplant surface or preemergence 
applications and Tables 2 and 3 for rates, weed growth stages and weeds controlled by 
postemergence applications. 
 
Emerged weeds must have thorough spray coverage for effective control. Refer to the 
Spray Adjuvants section for directions on spray adjuvants for postemergence weed 
control. 
 
Moisture is necessary to activate Flexstar GT 3.5 in soil for residual weed control. Dry 
weather following application of Flexstar GT 3.5 may reduce effectiveness of residual 
activity. When adequate moisture is not received within 7 days after a Flexstar GT 3.5 
application, residual weed control may be improved with at least a ¼ inch of overhead 
irrigation.

Page 33 
 
 
Preplant Surface or Preemergence Tank-Mix Applications - Soybeans 
 
Flexstar GT 3.5 can be tank mixed with the following products for preplant surface or 
preemergence applications in glyphosate-tolerant and non-glyphosate-tolerant 
soybeans: 2,4-D, Dicamba, Glyphosate products (such Roundup brands). 
 
It is the pesticide user’s responsibility to ensure that all products are registered for the 
intended use. Read and follow the applicable restrictions and limitations and directions 
for use on all product labels involved in tank mixing. Users must follow the most 
restrictive directions for use and precautionary statements of each product in the tank 
mixture. 
 
Postemergence Over-The-Top Applications in Glyphosate-Tolerant Soybeans 
 
Flexstar GT 3.5 can provide postemergence control of a broad spectrum of grass and 
broadleaf weeds as an over-the-top application in glyphosate-tolerant soybeans. Refer 
to Tables 2 and 3 for specific directions on weed growth stages, rates and weeds 
controlled. Emerged weeds must have thorough spray coverage for effective control. 
Refer to the Spray Adjuvants section for directions on spray adjuvants for 
postemergence weed control. 
 
Postemergence, in-crop applications of Flexstar GT 3.5 that come in contact with soil 
may control or partially control certain germinating broadleaf weeds and sedges. 
 
Some bronzing, crinkling or spotting of soybean leaves may occur following 
postemergence applications, but soybeans soon outgrow these effects and develop 
normally. 
 
Postemergence Split Application Program for Glyphosate-Tolerant Soybeans in 
Regions 1 and 2 
 
A postemergence split application of Flexstar GT 3.5 may be applied in Regions 1 and 
2. Apply Flexstar GT 3.5 at 2.65 pt/A with methylated seed oil (MSO) adjuvant at 1% 
v/v when weeds are 1 to 2 inches in height followed by a second application of Flexstar 
GT 3.5 at 2.65 pt/A with MSO at 1% v/v when re-growth or newly emerged weeds are 1 
to 2 inches in height (approximately 10-14 days after the first application). The total 
amount of Flexstar GT 3.5 in the split application program cannot exceed 5.3 pt/A. 
 
Special Postemergence Use Rate for Specific Weed Control Situations for 
Glyphosate-Tolerant Soybeans in Regions 1, 2, 3 and 4. 
 
Flexstar GT 3.5 may be applied at 2.8 pt/A in Regions 1, 2, 3 and 4 as a postemergence 
application to control non-glyphosate resistant weeds including difficult to control weeds 
such as morningglory, velvetleaf and black nightshade in glyphosate-tolerant soybeans. 
Apply when weeds are 1-4 inches in height.

Page 34 
 
 
Special Postemergence Use Rate for Specific Weed Control Situations for 
Glyphosate-Tolerant Soybeans in Region 5. 
 
Flexstar GT 3.5 may be applied at 2.68 pt/A in Region 5 as a postemergence 
application to control non-glyphosate resistant weeds including difficult to control weeds 
such as velvetleaf and black nightshade in glyphosate-tolerant soybeans. Apply when 
weeds are 1-3 inches in height. 
 
Postemergence Over-The-Top Tank-Mix Applications - Glyphosate-Tolerant 
Soybeans Only 
 
Flexstar GT 3.5 can be tank mixed with the following products for postemergence 
applications in glyphosate-tolerant soybeans: Dual Magnum®, Fusilade® DX, Fusion®, 
and Glyphosate products (such as Roundup brands). 
 
It is the pesticide user’s responsibility to ensure that all products are registered for the 
intended use. Read and follow the applicable restrictions and limitations and directions 
for use on all product labels involved in tank mixing. Users must follow the most 
restrictive directions for use and precautionary statements of each product in the tank 
mixture. 
 
Use Restrictions - Soybeans 
 
x DO NOT apply Flexstar GT 3.5 as an over-the-top application to non-glyphosate-
tolerant soybeans as plant death will occur. 
x Refer to Flexstar GT 3.5 Regional Use Map for the maximum rate of Flexstar GT 3.5 
(or other fomesafen-containing products) that may be applied in each geographic 
region. Do not apply to any field in Regions 2, 3, 4, or 5 more than once every other 
year. 
x Do not exceed 5.3 pints of Flexstar GT 3.5 per acre in any one year and also adhere 
to the maximum rate that may be applied in each geographic region (refer to the 
Flexstar GT 3.5 Regional Use Map). 
 
 
Flexstar GT 3.5 Herbicide Use Restrictions for Soybeans 
 
 
 
Region 
 
Maximum Single Application 
Flexstar GT 3.5 Rate (pt/A) 
 
Maximum 
Number 
Applications at Maximum Single Application 
Rate 
 
 
PHI 
(days) 
1 5.3 1 per year 45 
2 5.3 1 every other year 45 
3 4.5 1 every other year 45 
4 3.5 1 every other year 45 
4a 3.5 1 every other year 45 
5 2.68 1 every other year 45 
x In Region 4a, do not make a Flexstar GT 3.5 application later than June 20th. Cumulative rainfall plus overhead irrigation 
must total 15 inches from the period of Flexstar GT 3.5 application to soybean crop maturity to allow planting of rotational 
crops listed in this label (refer to Rotational Crop Restrictions section). If the soybean crop is lost or the required 
cumulative rainfall plus irrigation is not received as outlined above, plant only soybeans the following growing season. 
x Do not graze treated areas or harvest for forage or hay.

Page 35 
 
 
STORAGE AND DISPOSAL 
 
Do not contaminate water, food or feed by storage or disposal. 
 
Pesticide Storage 
 
Store above 10°F. If product freezes, return to room temperature and agitate to 
reconstitute. Keep container closed when not in use. Do not store near food or feed. In 
case of spill or leak on floor or paved surfaces, soak up with sand, earth or synthetic 
absorbent. Remove to chemical waste area. 
 
Pesticide Disposal 
 
Pesticide wastes are acutely hazardous. Improper disposal of excess pesticide, spray 
mixture or rinsate is a violation of Federal Law. If these wastes cannot be disposed of 
by use according to label instructions, contact your State Pesticide or Environmental 
Control Agency or the Hazardous Waste Representative at the nearest EPA Regional 
Office for guidance. 
 
Container Handling [less than or equal to 5 gallons] 
 
Non-refillable container. Do not reuse or refill this container. Triple rinse container (or 
equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining 
contents into application equipment or a mix tank and drain for 10 seconds after the flow 
begins to drip. Fill the container ¼ full with water and recap. Shake for 10 seconds. 
Pour rinsate into application equipment or a mix tank or store rinsate for later use or 
disposal. Drain for 10 seconds after the flow begins to drip. Repeat this procedure two 
more times. Then offer for recycling if available or puncture and dispose of in a sanitary 
landfill, or by incineration, or by other procedures approved by state and local 
authorities. 
 
Container Handling [greater than 5 gallons] 
 
Non-refillable container. Do not reuse or refill this container. Triple rinse container (or 
equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining 
contents into application equipment or a mix tank. Fill the container ¼ full with water. 
Replace and tighten closures. Tip container on its side and roll it back and forth, ensuring 
at least one complete revolution, for 30 seconds. Stand the container on its end and tip 
it back and forth several times. Turn the container over onto its other end and tip it back 
and forth several times. Empty the rinsate into application equipment or a mix tank or 
store rinsate for later use or disposal. Repeat this procedure two more times. Then offer 
for recycling if available or puncture and dispose of in a sanitary landfill, or by incineration, 
or by other procedures approved by state and local authorities.

Page 36 
 
 
Container Handling [greater than 5 gallons] 
 
Refillable container. Refill this container with pesticide only. Do not reuse this 
container for any other purpose. Cleaning the container before final disposal is the 
responsibility of the person disposing of the container. Cleaning before refilling is the 
responsibility of the person refilling. To clean container before final disposal, empty the 
remaining contents from this container into application equipment or mix tank. Fill the 
container about 10 percent full with water. Agitate vigorously or recirculate water with 
the pump for 2 minutes. Pour or pump rinsate into application equipment or rinsate 
collection system. Repeat this rinsing procedure two more times. Then offer for 
recycling if available or puncture and dispose of in a sanitary landfill, or by incineration, 
or by other procedures approved by state and local authorities. 
 
For minor spills, leaks, etc., follow all precautions indicated on this label and clean up 
immediately. Take special care to contain spills, leaks, and other accidents to prevent 
further exposure of facilities and equipment. Absorb spilled product with absorbing 
materials and dispose of in an approved waste disposal facility. In the event of a major 
spill, fire, or other emergency, call 1-800-888-8372, day or night. 
 
CONTAINER IS NOT SAFE FOR FOOD, FEED OR DRINKING WATER.

Page 37 
 
 
 
CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY 
 
NOTICE: Read the entire Directions for Use and Conditions of Sale and Limitation of 
Warranty and Liability before buying or using this product. If the terms are not 
acceptable, return the product at once, unopened, and the purchase price will be 
refunded. 
 
The Directions for Use of this product must be followed carefully. It is impossible to 
eliminate all risks inherently associated with the use of this product. Crop injury, 
ineffectiveness or other unintended consequences may result because of such factors 
as manner of use or application, weather or crop conditions, presence of other materials 
or other influencing factors in the use of the product, which are beyond the control of 
SYNGENTA CROP PROTECTION, LLC or Seller. To the extent permitted by 
applicable law, Buyer and Use agree to hold SYNGENTA and Seller harmless for any 
claims relating to such factors. 
 
SYNGENTA warrants that this product conforms to the chemical description on the label 
and is reasonably fit for the purposes stated in the Directions for Use, subject to the 
inherent risks referred to above, when used in accordance with directions under normal 
use conditions. To the extent permitted by applicable law: (1) this warranty does not 
extend to the use of the product contrary to label instructions or under conditions not 
reasonably foreseeable to or beyond the control of Seller or SYNGENTA, and, (2) 
Buyer and User assume the risk of any such use. TO THE EXTENT PERMITTED BY 
APPLICABLE LAW, SYNGENTA MAKES NO WARRANTIES OF MERCHANTABILITY 
OR OF FITNESS FOR A PARTICULAR PURPOSE NOR ANY OTHER EXPRESS OR 
IMPLIED WARRANTY EXCEPT AS WARRANTED BY THIS LABEL. 
 
To the extent permitted by applicable law, in no event shall SYNGENTA be liable for 
any incidental, consequential or special damages resulting from the use or handling of 
this product. TO THE EXTENT PERMITTED BY APPLICABLE LAW, THE 
EXCLUSIVE REMEDY OF THE USER OR BUYER, AND THE EXCLUSIVE LIABILITY 
OF SYNGENTA AND SELLER FOR ANY AND ALL CLAIMS, LOSSES, INJURIES 
OR DAMAGES (INCLUDING CLAIMS BASED ON BREACH OF WARRANTY, 
CONTRACT, NEGLIGENCE, TORT, STRICT LIABILITY OR OTHERWISE) 
RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, SHALL BE THE 
RETURN OF THE PURCHASE PRICE OF THE PRODUCT OR, AT THE ELECTION 
OF SYNGENTA OR SELLER, THE REPLACEMENT OF THE PRODUCT. 
 
SYNGENTA and Seller offer this product, and Buyer and User accept it, subject to the 
foregoing Conditions of Sale and Limitation of Warranty and Liability, which may not be 
modified except by written agreement signed by a duly authorized representative of 
SYNGENTA.

Page 38 
 
 
Caparol®, Dual Magnum®, Flexstar® GT 3.5, Fusilade® DX, Fusion®, ISOLINK™ 
Technology II, Solicam®, Touchdown®, the ALLIANCE FRAME the SYNGENTA Logo 
and the PURPOSE ICON are Trademarks of a Syngenta Group Company 
 
Cotoran® trademark of Makhteshim Agan of North America, Inc. 
 
Direx®, Karmex®, Staple®, and Viton® trademarks of E. I. du Pont de Nemours and 
Company 
 
Prowl® trademark of BASF Ag Products 
 
Roundup® and Roundup Ready® trademarks of Monsanto Company 
 
©201_ Syngenta 
 
 
For non-emergency (e.g., current product information) call 
Syngenta Crop Protection at 1-800-334-9481 
 
 
Manufactured for: 
Syngenta Crop Protection, LLC 
P. O. Box 18300 
Greensboro, North Carolina 27419-8300 
 
FLEXSTAR GT 3.5 1385 MAS 0415 AMEND MAY2018-Ver B– mar – 9/17/18 
000100-01385.20180529B.FLEXSTAR_GT_3.5_AMEND-MAY2018.pdf 
 
FLEXSTAR GT 3.5 1385 MAS 0415 AMEND MAY2018-Ver B-HI– mar – 9/17/18 
000100-01385.20180529B.FLEXSTAR_GT_3.5_AMEND-MAY2018-HI.pdf 
 
FLEXSTAR GT 3.5 1385 MAS 0415 AMEND MAY2018-HI– mar – 05/29/18 
000100-01385.20180529.FLEXSTAR_GT_3.5_AMEND-MAY2018-HI.pdf 
 
FLEXSTAR GT 3.5 1385 MAS 0415 AMEND MAY2018-Ver C– dlk – 9/19/19 
000100-01385.20180529C.FLEXSTAR_GT_3.5_AMEND-MAY2018.pdf