crop-chem-docs/corpus/epa_ppls/279-3557.md

# TOPGUARD FUNGICIDE

- EPA Reg No: **279-3557**
- Registrant: FMC CORPORATION 
- Signal word: Caution
- Active ingredients: Flutriafol (11.8%)
- Label accepted: 2023-08-18
- Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000279-03557-20230818.pdf

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UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 
 WASHINGTON, DC 20460 
OFFICE OF CHEMICAL SAFETY 
AND POLLUTION PREVENTION 
 
Notification ABN or Label Acceptable v.20220527 
August 18, 2023 
 
Paula Bodey 
Senior Product Registration Manager 
FMC Corporation 
2929 Walnut Street 
Philadelphia, PA 19104 
 
Subject: Notification per PRN 98-10 – add optional language for California 
 Product Name: Topguard Fungicide 
 EPA Registration Number: 279-3557 
 Application Date: 5/25/2022 
 Decision Number: 585374 
 
Dear Paula Bodey: 
 
The Agency is in receipt of your Application for Pesticide Notification under Pesticide Registration 
Notice (PRN) 98-10 for the above referenced product. The Registration Division (RD) has conducted 
a review of this request for its applicability under PRN 98-10 and finds that the action requested falls 
within the scope of PRN 98-10. 
 
Should you wish to add/retain a reference to the company’s website on your label, then please be 
aware that the website becomes labeling under the Federal Insecticide, Fungicide, and Rodenticide 
Act (FIFRA) and is subject to review by the Agency. If the website is false or misleading, the 
product would be misbranded and unlawful to sell or distribute under FIFRA section 12(a)(1)(E). 40 
CFR 156.10(a)(5) lists examples of statements EPA may consider false or misleading. In addition, 
regardless of whether a website is referenced on your product’s label, claims made on the website 
may not substantially differ from those claims approved through the registration process. Therefore, 
should the Agency find or if it is brought to our attention that a website contains false or misleading 
statements or claims substantially differing from the EPA approved registration, the website will be 
referred to the EPA’s Office of Enforcement and Compliance. 
 
If you have any questions, please contact Carmen Swinger at swinger.carmen@epa.gov. 
 
Sincerely, 
 
Nathan Mellor, Product Manager 21 
Fungicide Branch 
Registration Division (7505T) 
Office of Pesticide Programs

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
 1 
 
 
 
 
 
 
FLUTRIAFOL Group 3 Fungicide 
 
TOPGUARD® 
Fungicide 
 
{Alternate Brand Name: TOPGUARD® Fungicide Specialty Crops} 
{When an alternate brand name is used, it will also be used in the body of the label.} 
 
For use on alfalfa, barley, corn (field corn, field corn grown for seed, sweet corn, and 
popcorn); cotton (foliar application only); vegetables, cucurbit, group 9 (excluding 
muskmelons); vegetables, fruiting, group 8-10; grapes (fresh, juice, table, wine, raisin); 
hops, peanut; pome fruit (apple, crabapple, loquat, Mayhaw, pear, oriental pear, 
quince); grain sorghum; soybean; stone fruit; sugar beet; pecan and other tree nuts; 
triticale; wheat (spring and winter). 
 
 
ACTIVE INGREDIENT: 
*Flutriafol 11.8% 
OTHER INGREDIENTS: 88.2% 
TOTAL: 100.0% 
*Contains 1.04 pounds per gallon of the active ingredient flutriafol. 
Suspension concentrate. 
 
Keep Out of Reach of Children 
CAUTION / PRECAUCION 
 
Si usted no entiende la etiqueta, busque a alguien para que se la explique a usted en 
detalle. 
(If you do not understand the label, find someone to explain it to you in detail.) 
 
IN CASE OF A MEDICAL EMERGENCY INVOLVING THIS PRODUCT, CALL 
TOLL FREE, DAY OR NIGHT, 1-800- 331-3148 
 
 – OR – 
 
For MEDICAL 
EMERGENCY 
1-866-331-3148 
For SPILLS 
CHEMTREC 
1-800-424-9300 
 
279-3557
08/18/2023

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
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Notice: Read the entire Directions for Use and Conditions of Sale and Limitation of 
Warranty and Liability before buying or using this product. If the terms are not 
acceptable, return the product at once, unopened, and the purchase price will be 
refunded. 
 
 
Note to PM, the following bracketed statements are individually optional depending on 
the packaging configuration and whether a booklet label design is used: 
 
a. [See First Aid statement on back [label] [panel] [of booklet]]. 
b. [See additional precautionary statements and Directions for Use in booklet.] 
c. [Read the entire label before using this product.] 
d. [See First Aid, Precautionary Statements, and Directions for Use on individual 
packages.] 
 
 
 
EPA Reg. No. 279-3557 EPA Est. No._______ Net Contents: _____ 
 
 
Sold by:
 
FMC Corporation 
2929 Walnut Street 
Philadelphia, PA 19104 
 
 
 
TOPGUARD is a registered trademark of FMC

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
 3 
PRECAUTIONARY STATEMENTS 
 
HAZARDS TO HUMANS AND DOMESTIC ANIMALS 
Caution. Harmful if absorbed through skin. Harmful if swallowed. Causes moderate eye 
irritation. Avoid contact with skin, eyes or clothing. Prolonged or frequently skin contact 
may cause allergic reactions in some individuals. 
 
FIRST AID 
If on skin: 
- Take off contaminated clothing. 
- Rinse skin immediately with plenty of water for 15-20 minutes. 
- Call a poison control center or doctor for treatment advice. 
 
If swallowed: 
- Call a poison control center or doctor immediately for treatment advice. 
- Have person sip a glass of water if able to swallow. 
- Do not induce vomiting unless told to by a poison control center or doctor. 
- Do not give anything by mouth to an unconscious person. 
 
If in eyes: 
- Hold eye open and rinse slowly and gently with water for 15-20 minutes. 
- Remove contact lenses, if present, after the first 5 minutes, then continue rinsing. 
- Call a poison control center or doctor for treatment advice. 
Have the product container or label with you when calling a poison control center or 
doctor, or going for treatment. You may also contact 1-800-331-3148 for emergency 
medical treatment information. 
Note to Physician: No specific antidote. Treat symptomatically. 
 
 
PERSONAL PROTECTIVE EQUIPMENT (PPE) 
Applicators and all other handlers must wear: long-sleeved shirt and long pants, 
chemical-resistant gloves, and shoes plus socks. 
 
Follow manufacturer’s instructions for cleaning/maintaining PPE. If no such instructions 
for washables exist, use detergent and hot water. Keep and wash PPE separately from 
other laundry. 
 
ENGINEERING CONTROLS STATEMENT 
When handlers use closed systems, enclosed cabs, or aircraft in a manner that meets 
the requirements listed in the Worker Protection Standard (WPS) for agricultural 
pesticides [40 CFR 170.240(d)(4-6)], the handler PPE requirements may be reduced or 
modified as specified in the WPS.

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
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ENVIRONMENTAL HAZARDS 
This formulated product is toxic to fish and aquatic invertebrates. Do not apply directly 
to water, or to areas where surface water is present or to intertidal areas below the 
mean high water mark. Do not contaminate water when disposing of equipment 
washwater or rinsate. 
 
Ground Water Advisory: Flutriafol has properties and characteristics associated with 
chemicals detected in ground water. This chemical may leach into ground water if used 
in areas where soils are permeable, particularly where the water table is shallow. 
 
Surface Water Advisory: This product may impact surface water quality due to runoff of 
rain water. This is especially true for poorly draining soils and soils with shallow ground 
water. This product is classified as having a high potential for reaching surface water 
via runoff for several months or more after application. 
 
 
USER SAFETY RECOMMENDATIONS 
Users should: Wash hands before eating, drinking, chewing gum, using tobacco or 
using the toilet. 
Remove clothing/PPE immediately if pesticide gets inside. Then wash thoroughly 
and put on clean clothing. Remove PPE immediately after handling this product. 
Wash the outside of gloves before removing. As soon as possible, wash thoroughly 
and change into clean clothing.

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
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DIRECTIONS FOR USE 
 
It is a violation of Federal law to use this product in any manner inconsistent with its 
labeling. Do not apply this product in a way that will contact workers or other persons, 
either directly or through drift. Only protected handlers may be in the area during 
application. For any requirements specific to your State or Tribe, consult the agency 
responsible for pesticide regulation. 
 
[Note to Reviewer: Below is optional state specific language.] 
 
[Optional language for CA: In California, this product may only be applied to 
fields that are not irrigated, or are irrigated using pressurized irrigation methods 
such as macro-sprinkler, micro-sprinkler, or drip systems.] 
 
[Optional language for NY: Not for sale, distribution, or use in Nassau or Suffolk 
Counties of New York State.] 
 
AGRICULTURAL USE REQUIREMENTS 
Use this product only in accordance with its labeling and with the Workers Protection 
Standard, 40 CFR part 170. This Standard contains requirements for the protection of 
agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of 
agricultural pesticides. It contains requirements for training, decontamination, 
notification and emergency assistance. It also contains specific instructions and 
exceptions pertaining to the statements on this label about Personal Protective 
Equipment (PPE) and restricted-entry interval. The requirements in this box only apply 
to uses of this product that are covered by the Worker Protection Standard. 
 
Do not enter or allow worker entry into treated areas during the restricted entry interval 
(REI). The REI for each crop is located in the use directions for each crop. 
 
PPE required for early entry to treated areas that is permitted under the Worker 
Protection Standard and that involves contact with anything that has been treated, such 
as plants, soil or water, is: coveralls, chemical resistant gloves, and shoes plus socks. 
 
STORAGE AND DISPOSAL 
Do not contaminate water, food or feed by storage or disposal. 
 
Pesticide Storage: Store unused product in original container in a cool, dry, secure 
area. 
 
Pesticide Disposal: Pesticide wastes may be hazardous. Improper disposal of excess 
pesticide, spray mixture or rinsate is a violation of Federal Law. If these wastes cannot 
be disposed of by use according to label instructions, contact your State Pesticide or 
Environmental Control Agency, or the Hazardous Waste Representative at the nearest 
EPA Regional Office for guidance.

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
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Container Handling: 
Nonrefillable container. [equal to or less than 5 gallons] 
Do not reuse or refill this container. Offer for recycling if available or puncture and 
dispose of in a sanitary landfill, or by incineration, or, if allowed by state and local 
authorities, by burning. If burned, stay out of smoke. 
Triple rinse as follows: Empty the remaining contents into application equipment or a 
mix tank and drain for 10 seconds after the flow begins to drip. Fill the container ¼ full 
with water and recap. Shake for 10 seconds. Pour rinsate into application equipment 
or a mix tank or store rinsate for later use or disposal. Drain for 10 seconds after the 
flow begins to drip. Repeat this procedure 2 more times. 
 
Nonrefillable container. [greater than 5 gallons] [and less than 260 gallons] 
Do not reuse or refill this container. Offer for recycling if available, or puncture and 
dispose of in a sanitary landfill, or by incineration, or if allowed by state and local 
authorities, by burning. If burned, stay out of smoke. 
Triple rinse or pressure rinse as follows: 
Triple rinse as follows: Empty the remaining contents into application equipment or mix 
tank. Fill the container ¼ full with water. Replace and tighten closures. Tip container 
on its side and roll it back and forth, ensuring at least one complete revolution, for 30 
seconds. Stand the container on its end and tip it back and forth several times. Turn 
the container over onto its other end and tip it back and forth several times. Empty the 
rinsate into application equipment or a mix tank and store rinsate for later use or 
disposal. Repeat this procedure two more times. 
Pressure rinse as follows: Empty the remaining contents into application equipment or a 
mix tank and continue to drain for 10 seconds after the flow begins to drip. Hold 
container upside down over application equipment or a mix tank or collect rinsate for 
later use or disposal. Insert pressure rinsing nozzle in the side of the container, and 
rinse at about 40 PSI for at least 30 seconds. Drain for 10 seconds after the flow begins 
to drip. 
 
{Note to PM, IBC’s may be nonrefillable or refillable, the container handling section will 
state either Nonrefillable or Refillable.} 
Nonrefillable container. {or} 
Refillable container. 
Bottom discharge IBC. 
Pressure rinsing the container before final disposal is the responsibility of the person 
disposing of the container. To pressure rinse the container before final disposal, empty 
the remaining contents from the IBC into application equipment or mix tank. Raise the 
bottom of the IBC by 1.5 inches on the side which is opposite of the bottom discharge 
valve to promote more complete product removal. Completely remove the top lid of the 
IBC. Use water pressurized to at least 40 PSI to rinse all interior portions. Continuously 
pump or drain rinsate into application equipment or rinsate collection system while 
pressure rinsing. Continue pressure rinsing for 2 minutes or until rinsate becomes 
clear. Replace the lid and close bottom valve.

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
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PRODUCT DIRECTIONS 
 
READ ENTIRE LABEL. USE STRICTLY IN ACCORDANCE WITH 
PRECAUTIONARY STATEMENTS AND DIRECTIONS, AND WITH APPLICABLE 
STATE AND FEDERAL REGULATIONS. 
 
Not for use in greenhouses. 
 
Chemigation: 
 
Application through Irrigation Systems (Chemigation): 
Apply TOPGUARD Fungicide through irrigation to crops at rates and timings specified in 
this label. Chemical tank and injector system must be thoroughly cleaned before and 
after use. Flush system with clean water. 
 
Drip Irrigation: Use TOPGUARD Fungicide for control of diseases at rates and timing as 
specified in this label. Ensure adequate soil moisture prior to utilizing TOPGUARD 
Fungicide in a drip irrigation system. Do not apply TOPGUARD Fungicide through drip 
irrigation that is deeper than 12” below the soil surface. 
 
Discontinue drip irrigation application at fungicide depletion from the main feed supply 
tank or after 6 hours from start, whichever is shorter. Delay subsequent irrigation (water 
only) for at least 24 hours following drip application for best results. 
 
Sprinkler Irrigation: Apply this product through sprinkler irrigation systems including 
center pivot, lateral move, end tow, side (wheel) roll, traveler, big gun, solid set, micro 
sprinkler or hand move irrigation systems. Do not apply this product through any other 
type of irrigation system except as specified on this label. 
 
With Center Pivot irrigation equipment, use TOPGUARD Fungicide only with equipment 
with drive systems that provide uniform water distribution. Do not use end guns for 
chemigation due to the non-uniform application pattern. 
 
Add TOPGUARD Fungicide to the pesticide supply tank containing sufficient water to 
maintain a continuous flow by the injection equipment. Maintain agitation during the 
entire application period. 
 
For continuous-move irrigation systems, apply the labeled rate for that crop in ½ acre-inch 
or less per acre. For stationary or non-continuous moving systems, inject TOPGUARD 
Fungicide spray mixture during the last 20-30 minutes of the set. 
 
Do not apply when winds are greater than 10-15 mph to avoid drift or wind skips. Do not 
apply when wind speed favors drift beyond the area intended for treatment. Crop injury, 
lack of effectiveness, or illegal pesticide residues in the crop can result from non-uniform 
distribution of treated water. Thorough coverage of foliage is required for good control.

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
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If you have questions about calibration you should contact a State Extension Service 
specialist, equipment manufacturer or other expert. 
 
Operating Requirements for Application through Irrigation Systems: 
1. Do not use chemigation when conditions are favorable for drift to non-target areas. 
2. To prevent water-source contamination from backflow, a functional check valve, 
vacuum relief valve, and low-pressure drain should be located on the irrigation 
pipeline. 
3. To prevent backflow back toward the injection pump, the pesticide injection pipeline 
must be equipped with a functional, automatic, quick-closing check valve. 
4. To prevent fluid from being withdrawn from the supply tank when the irrigation system 
is shut down, the pesticide injection pipeline should also be equipped with a 
functional, normally closed, solenoid-operated valve located on the intake side of the 
injection pump and connected to the system interlock. 
5. The system must also contain functional interlocking controls to automatically shut off 
the pesticide injection pump when the water pump motor stops and a functional 
pressure switch to stop the pump motor when water pressure decreases to a point at 
which pesticide distribution is adversely affected. 
6. A metering pump, constructed of materials compatible with pesticides and capable of 
being fitted with a system interlock, such as a positive displacement injection pump 
(e.g., a diaphragm pump), must be included in the system. 
7. A knowledgeable person responsible for the chemigation system should shut the 
system down and turn the irrigation water off, ensuring enough time for the pesticide 
to be flushed through all lines and nozzles. 
8. No irrigation system, including those in greenhouses, used to distribute pesticides can 
be connected to a public water source unless safety measures and devices prescribed 
in the pesticide label for such connection are in place. 
 
Specific Instructions for Public Water Systems: 
1. Public water system means a system that provides piped water for human 
consumption if the system has at least 15 service connections or regularly serves an 
average of at least 25 individuals daily at least 60 days out of the year. 
2. All measures and devices listed in the above section, “Operating Requirements for 
Application through Irrigation Systems”, must be operational for connection to a public 
water system. 
3. Additionally, chemigation systems connected to public water systems must contain a 
functional, reduced-pressure zone, back-flow preventer (RPZ) or the functional 
equivalent in the water supply line upstream from the point of pesticide introduction. 
As an option to the RPZ, the water from the public water system should be discharged 
into a reservoir tank prior to pesticide introduction. There must be a complete physical 
break (air gap) between the outlet end of the fill pipe and the top or overflow rim of the 
reservoir tank of at least twice the inside diameter of the fill pipe. 
 
Rainfastness: TOPGUARD Fungicide is rainfast 2 hours after application. Disease 
control will be reduced if rainfall occurs within 2 hours of application.

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
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Crop Rotation: Fields treated with TOPGUARD Fungicide may be planted to the 
following crops and plant back intervals: 
 
 
Crop Plant back Interval 
Alfalfa, barley, field corn; field corn grown 
for seed; popcorn; sweet corn; cotton; 
cucurbits; fruiting vegetables; grapes; 
hops; Brassica leafy vegetables crop 
group 5; leafy vegetables, except 
Brassica, crop group 4; peanut; pome 
fruit; grain sorghum; soybean; stone fruit; 
strawberry; sugar beet; tomato; tree nuts; 
triticale; or wheat 
Immediately 
Rice 30 days 
All other crops Prohibited 
 
 
RATE EQUIVALENCY TABLE 
Product Rate 
(fl. oz./A) 
Equivalent Active Ingredient Rate 
(lb a.i./A) 
7 0.057 
8 0.065 
10 0.081 
12 0.098 
13 0.106 
14 0.114 
16 0.130 
24 0.20 
30 0.24 
32 0.26 
48 0.39 
 
 
Compatibility Jar Test: TOPGUARD Fungicide is compatible with most products, 
however not all combinations have been tested. Use the following compatibility jar test 
to ensure physical compatibility. 
 
Using a quart jar, add the proportionate amounts of the products to approximately one 
quart of water with agitation. Add wettable powders and water dispersible granular 
products first, next liquid flowables, then emulsifiable concentrates, and last liquid 
soluble products. After thorough mixing, allow this mixture to stand for 5 minutes. If the 
combination remains mixed or can be readily remixed, it is physically compatible. Once 
compatibility has been proven, use the same procedure for adding products to the spray 
tank. Use tank mix combinations on a small number of plants before treating larger

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
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areas. When tank mixing, follow more restrictive labeling of any tank mix partner. Do 
not tank mix with any product that contains a prohibition on tank mixing. 
 
Use of Adjuvants: An adjuvant may be used with TOPGUARD Fungicide unless 
otherwise specified in the crop use directions. TOPGUARD Fungicide is compatible 
with most products, however not all have been tested. Use the compatibility jar test to 
ensure physical compatibility. 
 
Tank Mixing: TOPGUARD Fungicide may be tank mixed with other fungicides, 
herbicides, insecticides, and/or other additives unless prohibited on the label of the 
tank mix partner. Follow more restrictive labeling of any tank mix partner. Although 
TOPGUARD Fungicide is compatible with most products, not all combinations have 
been tested. Use the compatibility jar test to ensure physical compatibility. Before 
applying any tank mixture not specifically recommended on this label, the crop safety 
of the target crop should be confirmed by applying the mixture to a small area of the 
target crop in accordance to the label instructions. It is the pesticide user’s 
responsibility to ensure that all products are registered for the intended use. Read and 
follow the applicable restrictions and limitations and directions for use on all product 
labels involved in tank mixing. Users must follow the most restrictive directions for use 
and precautionary statements of each product in the tank mixture. 
 
Spray Equipment/Volume: TOPGUARD Fungicide should be applied in sufficient 
water volume to ensure thorough coverage as a broadcast foliar application for good 
disease control. 
 
For ground application, use a minimum of 10 gallons of spray solution per acre by 
ground sprayer. For aerial application, use aircraft spray equipment in a minimum of 10 
gallons of spray solution per acre for tree nut crops, 2 gallons of spray solution per acre 
for corn, cotton, grain sorghum, soybean, wheat and triticale, and 5 gallons of spray 
solution per acre for all other crops. 
 
Resistance Management: 
 
For resistance management, TOPGUARD Fungicide contains a Group 3 fungicide 
(Flutriafol.) 
 
Any fungal population may contain individuals naturally resistant to TOPGUARD 
Fungicide and other Group
 3 fungicides. A gradual or total loss of pest control may 
occur over time if these fungicides are used repeatedly in the same fields. 
Appropriate resistance-management strategies should be followed. 
 
To delay fungicide resistance, take one or more of the following steps: 
 
• Rotate the use of TOPGUARD Fungicide or other Group 3 fungicides within a 
growing season sequence with different groups that control the same 
pathogens.

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
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• Use tank mixtures with fungicides from a different group that are equally 
effective on the target pest when such use is permitted. Use at least the 
minimum application rate as labeled by the manufacturer. 
 
• Adopt an integrated disease management program for fungicide use that 
includes scouting, uses historical information related to pesticide use, and crop 
rotation, and which considers host plant resistance, impact of environmental 
conditions on disease development, disease thresholds, as well as cultural, 
biological and other chemical control practices. 
 
• Where possible, make use of predictive disease models to effectively time 
fungicide applications. Note that using predictive models alone is not sufficient 
to manage resistance. 
 
• Monitor treated fungal populations for resistance development. 
 
• Contact your local extension specialist or certified crop advisor for any 
additional pesticide resistance-management and/or IPM recommendations for 
specific crops and pathogens. 
 
• For further information or to report suspected resistance contact your pesticide 
distributor or university extension specialist to report resistance. 
 
High Disease Pressure: Where a range is given, use the higher rate of TOPGUARD 
Fungicide and/or reduced spray interval when disease pressure is high and/or 
conditions are favorable for disease development.

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
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CROP USE DIRECTIONS 
Use Directions for ALFALFA 
[Not for use in CA] 
 
TOPGUARD Fungicide works by forming a protective barrier around the alfalfa root at 
the point of disease infection. Precipitation in the form of rainfall or irrigation is required 
to move the product into the infection zone. The amount of water required will vary with 
soil type, soil moisture, and rainfall or irrigation intensity. 
 
Application Method: 
Apply TOPGUARD Fungicide as a broadcast spray application at a minimum spray 
volume of 10 gallons per acre or 5 gallons by air, or through sprinkler irrigations 
systems designed as described in the Chemigation section of this label. For continuous-
move irrigation systems, apply the labeled rate in ½ acre-inch or more per acre. For 
stationary or non-continuous moving systems, inject TOPGUARD Fungicide spray 
mixture during the first 20-30 minutes of the set to insure fungicide reaches the soil 
surface. Applications should be made postemergence to alfalfa at the timing(s) outlined 
below. 
 
Disease Product Rate 
fl oz/A 
Application Directions 
Texas Root Rot / 
Cotton Root Rot 
(Phymatotrichopsis 
omnivora) 
 
 
30 – 48 fl oz/A 
(0.24 – 0.39 lb 
ai/A) 
Single Application: 
Apply in early spring prior to three (3) inches of new 
growth on the alfalfa OR after first cut of alfalfa when 
alfalfa is between two (2) and three (3) inches 
regrowth. 
 
Use highest specified product rate when field is known 
to have high levels of cotton root rot disease pressure. 
 
First 
application: 
30 – 48 fl oz/A 
(0.24 – 0.39 lb 
ai/A) 
 
Second 
application: 
24 - 30 fl oz/A 
(0.2 – 0.24 lb 
ai/A) 
 
Split Application: 
Apply first application in early spring prior to three (3) 
inches of new growth on the alfalfa 
 
Apply second application after second or third cutting 
of alfalfa when alfalfa is between two (2) and three (3) 
inches regrowth. 
 
Use split application under the following situations: 
• High intensity production practices 
• 2
nd year of established plantings and older 
 
Use highest specified product rate when field is known 
to have high levels of cotton root rot disease pressure.

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
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Restrictions: 
• No single application may exceed 48 fl oz of product (0.39 lb ai)/A 
• Make only one application per cutting 
• Do not apply more than two applications per year. 
• Do not exceed 78 fl oz of product (0.63 lb ai)/A per year. 
• Preharvest Interval (PHI): Do not apply within 14 days of harvest 
• Restricted Entry Interval (REI) is 12 hours

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
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Use Directions for Corn (Field Corn, Field Corn Grown for Seed, Sweet Corn, and 
Popcorn) (Foliar Applications) 
[Not for use in CA] 
 
Diseases Product 
Rate 
(fl oz /A) 
Application Directions Application 
Interval 
(Days) 
Gray Leaf Spot 
 (Cercospora zeae-maydis) 
 
Southern Corn Leaf Blight 
 (Cochlibolus heterostrophus) 
 
Northern Corn Leaf Blight 
 (Setosphaeria turcica) 
 
Rust, Common 
 (Puccinia sorghi) 
 
Southern Rust 
 (Puccinia polysora) 
 
Eyespot 
 (Aureobasidium zeae) 
 
Anthracnose Leaf Blight 
 (Colletotrichum graminicola) 
 
Northern Corn Leaf Spot 
 (Cochliobolus carbonum) 
7 - 14 
 
(0.057-
0.114 lb 
ai/A) 
Apply preventatively or 
when conditions are 
favorable for disease 
development. One 
repeat application may be 
made. 
 
Apply no later than 
growth stage R4 (early 
dough stage). 
 
For aerial application, 
use a minimum of 2 
gallons of spray solution 
per acre. 
 
7 
Restrictions: 
• No single application may exceed 14 fl of product (0.114 lb ai) /A. 
• Do not apply more than 2 applications per year. 
• Do not apply more than 28 fl oz of product (0.228 lb ai)/A per year. 
• Do not apply more than 0.228 lb. ai of flutriafol/A per year. 
• An adjuvant may be used with TOPGUARD Fungicide prior to the V8 corn growth 
stage and after the VT corn growth stage. 
• Restricted Entry Interval (REI): The REI for detasselling field corn and popcorn 
grown for seed is 5 days. The REI for sweet corn is 3 days. The REI for all other 
activities is 12 hours. 
• Preharvest Interval: Zero (0) day of harvest for forage, and 7 days for stover and 
grain of field corn and popcorn.

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
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Use Directions for Corn (Field Corn, Field Corn Grown for Seed, Sweet Corn, and 
Popcorn) (At Planting Applications) 
[Not for use in CA] 
 
Diseases Product 
Rate 
(fl.oz./A) 
Application Directions 
Head Smut (Sphacelotheca 
reiliana) 
 
14 
 
(0.114 lb 
ai/A) 
See table below for rate chart depending 
on row width. 
 
Apply in 3 to 6 gallons of water per acre 
at planting. 
 
Methods of application: 
T-Band Application: Apply TOPGUARD 
Fungicide in a concentrated 3-4 inch 
wide band at planting with the spray tip 
oriented perpendicular to the row 
direction and with spray tip located after 
furrow opening and seed placement but 
prior to furrow closure with press wheel. 
 
In-Furrow / Modified In-Furrow 
Application: Apply in furrow using a 
mechanism that guides the product so 
as not to come into direct contact with 
the seed. 
 
Temporary corn height reductions are 
sometimes noted when TOPGUARD is 
applied in-furrow or by and T-band 
applications. The height reduction is 
temporary and plants will recover over a 
period of 2 to 3 weeks. 
 
Restrictions: 
• No single application may exceed 14 fl oz of product (0.114 lb ai)/A. 
• Do not apply more than 1 at planting and one foliar applications per year. 
• Do not apply more than 28 fl oz of product (0.228 lb ai)/A per year. 
• Do not apply more than 0.228 lb. ai of flutriafol/A per year. 
• Restricted Entry Interval (REI) is 12 hours for at-planting application. 
• Preharvest Interval (PHI): Zero (0) day of harvest for forage, and 7 days for stover 
and grain of field corn and popcorn. 
•

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
 16 
Rate Chart: Product Rate Depending on Row Width 
Row Spacing (inches) 
fl oz of TOPGUARD/1000 ft. of Row 
14 fl oz/A Rate 
20 0.59 
30 0.89 
32 0.91 
36 1.01 
38 1.16 
40 1.07 
20” = 23,760 row ft./A; 30” = 17,424 row ft./A; 32” = 16,315 row ft./A; 34” = 15,374 row ft./A; 36” = 14,520 
row ft./A; 38” = 13,754 row ft./A; 40” = 13,068 row ft./A. 
 
Formula: Selected Use Rate (fl oz/A___ = fl oz of product to be applied per 1000 row ft. 
 [Row ft for row spacing/1000 ft] 
 
Example of 30” row spacing at 14 fl oz/A: 
 14 fl oz/A = 0.59 fl oz of product to be applied per 1000 row ft. 
 [17,424/1000]

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
 17 
Use Directions for Cotton (foliar application only) 
[Not for use in CA] 
 
Diseases Product 
Rate 
(fl oz /A) 
Application Directions Application 
Interval 
(Days) 
Alternaria Leaf Spot, Boll Rot 
 (Alternaria spp.) 
 
Anthracnose, Boll Rot 
 (Glomerella spp.) 
 
Ascochyta Blight, Boll Rot 
 (Ascochyta gossypii) 
 
Cercospora Blight and Leaf 
Spot 
 (Cercospora spp.) 
 
Diplodia Boll Rot 
 (Diplopia spp.) 
 
Fusarium Boll Rot 
 (Fusarium spp.) 
 
Phoma Blight, Boll Rot 
 (Phoma spp.) 
 
Rust (Puccinia spp., 
 Phykopsora spp.) 
 
Stemphyllium Leaf Spot 
 (Stemphyllium spp.) 
 
Target Spot 
 (Corynespora cassiicola) 
7 - 14 
 
(0.057-
0.114 lb 
ai/A) 
Apply preventatively or when 
conditions are favorable for 
disease development. Repeat 
as necessary if conditions are 
favorable for disease 
development. 
 
7 
Restrictions: 
• No single application may exceed 14 fl oz of product (0.114 lb ai)/A. 
• Do not apply more than 2 foliar applications per year. 
• Do not apply more than 28 fl oz of product (0.228 lb ai)/A per year 
• Do not apply more than 0.228 lb ai of flutriafol/A per year (including foliar and soil 
applications.) 
• Restricted Entry Interval (REI): The REI is 12 hours. 
• Preharvest Interval (PHI): Do not apply within 30 days of harvest.

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
 18 
Use Directions for Vegetables, Cucurbit, Group 9 (excluding Muskmelons). 
See below for a list of crops. 
[Not for use in CA] 
 
Diseases Product 
Rate 
(fl oz/A) 
Application Directions Application 
Interval 
(Days) 
Powdery Mildew 
 (Sphaerotheca fuliginea, 
 Erysiphe cichoracearum) 
10 - 14 
 
(0.081-
0.114 lb 
ai/A) 
Apply preventatively or 
when conditions are 
favorable for disease 
development. Repeat as 
necessary if conditions are 
favorable for disease 
development. 
7 
Gummy Stem Blight 
 (Didymella bryoniae) 
 
Target Spot 
 (Corynespora cassiicola) 
 
10 - 14 
 
(0.081-
0.114 lb 
ai/A) 
Apply preventatively or 
when conditions are 
favorable for disease 
development. Repeat as 
necessary if conditions are 
favorable for disease 
development. 
 
Tank mix with KOVERALL 
Fungicide (mancozeb) for 
resistance management. 
 
In fields with known triazole 
resistance, apply 
TOPGUARD Fungicide with 
KOVERALL
® Fungicide or 
alternate fungicide group for 
disease control. 
7 
Soilborne Diseases: 
Charcoal Rot 
 (Macrophomina phaseolina) 
14 
 
(0.114 lb 
ai/A) 
Product is to be applied 
through drip irrigation (see 
Chemigation section). 
Make initial application at 
transplanting. Make a 
second application 30 days 
later. Additional applications 
may be made on a 30 day 
interval, as needed. 
30 
List of Cucurbits: Chayote (Fruit), Chinese Waxgourd, Citron Melon, Cucumber, Gherkin, 
Gourd Edible (Lagenaria spp.) (Hyotan, Cucuzza, Hechima, Chinese Okra), Momordica 
spp. ( Balsam Apple, Balsam Pear, Bittermelon, Chinese Cucumber), Pumpkin, Squash 
(Summer), Squash (Winter –Butternut Squash, Calabaza, Hubbard Squash, Acorn 
Squash, Spaghetti Squash), Watermelon*.

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
 19 
Restrictions: 
• No single application may exceed 14 fl oz of product (0.114 lb ai)/A. 
• Do not apply more than 4 applications per year. 
• Do not apply more than 56 fl oz of product (0.455 lb ai)/A per year. 
• Do not apply more than 0.455 lb ai of flutriafol/A per year. 
• Do not apply in consecutive applications. 
• Use non-ionic surfactants only 
• Restricted Entry Interval (REI) is 12 hours. 
• Preharvest Interval (PHI): May be applied the day of harvest (0 day PHI). 
 
Additional Watermelon only Restrictions: 
• Do not apply more than 2 sequential applications, including soil and foliar 
applications, before rotating with a fungicide from a different FRAC group. 
• Use nonionic surfactants (NIS) only. 
• Do not use organo silicone adjuvants, or crop oil concentrate (COC) surfactants. 
 
*Precaution for watermelon use: Under certain environmental conditions, applications of 
TOPGUARD Fungicide may result in phtyotoxicity symptoms that may reduce watermelon 
yields. FMC recommends the grower and/or user test this product to determine its 
suitability for use in watermelon. FMC provides this product to the grower and/or user 
solely to the extent that the benefit and utility, in the sole opinion of the grower and/or 
user, outweighs the potential of crop phytotoxicity following applications of TOPGUARD 
Fungicide to watermelon. The decision to use or not use TOPGUARD Fungicide
 in 
watermelon must be made by each individual grower and/or user on the basis of possible 
crop phytotoxicity, the severity of disease incidence, the cost of alternative disease control 
options, and other factors.

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
 20 
 
Use Directions for Grapes [(fresh, juice, table, wine, raisin)] 
[Not for use in CA] 
 
 
Diseases 
Product 
Rate 
(fl oz/A) 
 
Application Directions 
Application 
Interval 
(Days) 
Powdery Mildew 
 (Uncinula necator) 
 
8 - 10 
 
(0.065-
0.081 lb 
ai) 
Apply TOPGUARD Fungicide as a 
foliar spray beginning at 6 to 10 
inch shoots. 
 
14 to 21 
Black Rot 
 (Guignardia bidwellii) 
8 - 10 
(0.065-
0.081 lb 
ai) 
Apply preventatively or when 
conditions are favorable for 
disease development. Repeat as 
necessary if conditions are 
favorable for disease 
development. 
 
14 to 21 
Restrictions: 
• No single application may exceed 10 fl oz of product (0.081 lb ai)/A. 
• Do not apply more than 6 applications of product per year. 
• Do not apply more than 60 fl oz of product (0.488 lb ai)/A per year. 
• Do not apply more than 0.488 lb ai of flutriafol/A per year. 
• Restricted Entry Interval (REI): The REI for girdling or turning of grapes is 5 days. The 
REI for all other activities is 12 hours. 
• Preharvest Interval (PHI): Do not apply within 14 days of harvest.

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
 21 
Use Directions for Hops 
[Not for use in CA] 
 
Diseases Product 
Rate 
(fl oz/A) 
Application Directions Application 
Interval 
(Days) 
Powdery Mildew 
(Podosphaera macularis, 
Sphaerotheca macularis) 
 
 
10 – 14 
 
(0.081-
0.114 lb 
ai/A) 
Apply preventatively or 
when conditions are 
favorable for disease 
development. Repeat as 
necessary if conditions are 
favorable for disease 
development. 
 
Apply a minimum of 30 
gallons per acre spray 
volume for ground 
applications and 10 
gallons per acre for aerial 
applications. 
 
14 
Restrictions: 
• No single application may exceed 14 fl oz of product (0.114 lb ai)/A. 
• Do not apply more than 4 applications per year 
• Do not apply more than 56 fl oz of product (0.455 lb ai)/A per year 
• Do not apply more than 0.455 lb ai of flutriafol/A per year. 
• An adjuvant may be used with TOPGUARD Fungicide 
• Restricted Entry Interval (REI) is 12 hours 
• Preharvest Interval (PHI): Do not apply within 7 days of harvest

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
 22 
 
Use Directions for Peanut 
[Not for use in CA] 
 
Diseases Product 
Rate 
(fl oz /A) 
Application Directions Application 
Interval 
(Days) 
Early Leaf Spot 
 (Cercospora arachidicola) 
 
Late Leaf Spot 
 (Cercosporidium personatum) 
 
Peanut Rust 
 (Puccinia arachidis) 
 
Leaf Scorch/ Pepper Spot 
 (Leptosphaerulina crassiasca) 
 
Web Blotch 
 (Phoma arachidicola) 
7 - 14 
 
(0.057-
0.114 lb 
ai/A) 
Apply on a preventive spray 
schedule for effective 
disease control in peanuts. 
 
TOPGUARD Fungicide can 
be tank mixed with 
KOVERALL Fungicide 
(mancozeb) for improved 
disease control and 
resistance management. 
 
 
14 
Suppression of Soil-Borne 
Diseases: 
White Mold / Southern Stem Rot 
 (Sclerotium rolfsii) 
 
 
7 - 14 
 
(0.057-
0.114 lb 
ai/A) 
For soil-borne diseases, 
rainfall or irrigation will 
optimize activity of 
TOPGUARD® Fungicide. 
Tank-mix with other labeled 
fungicides for improved 
activity on soil-borne 
diseases. 
14 
Restrictions: 
• No single application may exceed 14 fl oz of product (0.114 lb ai)/A. 
• Do not apply more than 4 applications per year. 
• Do not apply more than 56 fl oz of product (0.455 lb ai)/A per year. 
• Do not apply more than 0.455 lb ai of flutriafol/A per year. 
• Restricted Entry Interval (REI) is 12 hours. 
• Preharvest Interval (PHI): Do not apply within 7 days of harvest.

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
 23 
Use Directions for Pecan and Other Tree Nuts. See below for list of crops. 
[Not for use in CA] 
 
Diseases Product 
Rate 
(fl oz/A) 
Application Directions Application 
Interval 
(Days) 
Pecan Scab 
 (Fusicladium effusum) 
 
Powdery Mildew 
 (Microsphaera penicillata) 
 
Alternaria Leaf and Fruit Spot 
 (Alternaria alternata) 
 
Anthracnose 
 (Colletotrichum acutatum) 
 
Shothole 
 (Wilsonomyces carpophilus) 
 
Eastern Filbert Blight 
 (Anisogramma anomale) 
 
Brown Rot Blossom Blight 
 (Monilinia fructicola) 
 
Leaf Rust 
 (Tranzschelia discolor) 
 
Downy Spot 
 (Mycosphaerella caryigena) 
 
Zonate Leaf Spot 
 (Cristulariella moricola) 
7 - 14 
 
(0.057-
0.114 lb 
ai/A) 
For Pecan Scab control, 
start application at bud 
break. Continue application 
10-14 days pre-pollination; 
14-21 days post-pollination. 
 
For all other disease apply 
preventatively or when 
conditions are favorable for 
disease development. 
Repeat as necessary if 
conditions are favorable for 
disease development. 
 
7 
 
List of Tree Nuts: African Tree Nut, Brazil Nut, Burr Oak, Butternut, Cajou, Cashew, 
Castanha-Do-Maranhao, Coconut, Coquito Nut, Dika nut, Guiana Chestnut, Hazelnut, 
Heartnut, Hickory Nut, Japanese Horse-Chestnut, Macadamia Nut, Monogongo Nut, 
Monkey-Pot, Pachira Nut, Pecan, Sapucaia Nut. 
Restrictions: 
• No single application may exceed 14 fl oz of product (0.114 lb ai)/A. 
• Do not apply more than 4 applications per year. 
• Do not apply more than 56 fl oz of product (0.455 lb ai)/A per year. 
• Do not apply more than 0.455 lb ai of flutriafol/A per year. 
• Restricted Entry Interval (REI) is 12 hours. 
• Preharvest Interval (PHI): Do not apply within 14 days of harvest.

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
 24 
• 
Use Directions for Vegetables, Fruiting, Group 8-10. 
See below for list of crops. 
[Not for use in CA] 
 
Diseases Product 
Rate 
(fl oz/A) 
Application Directions Application 
Interval 
(Days) 
Powdery Mildew 
 (Leveillula taurica) 
 
Anthracnose 
 (Colletotrichum coccedes, 
 C. acutatum) 
 
Cercospora Leaf Spot 
 (Cercospora capsici) 
 
14 
 
(0.114 lb 
ai/A) 
Apply preventatively or when 
conditions are favorable for 
disease development. 
Repeat as necessary if 
conditions are favorable for 
disease development. 
 
7 
Soilborne Diseases: 
Charcoal Rot 
 (Macrophomina phaseolina) 
14 
 
(0.114 lb 
ai/A) 
Product is to be applied 
through drip irrigation (see 
Chemigation section). Make 
initial application at 
transplanting. Make a 
second application 30 days 
later. Additional applications 
may be made on a 30 day 
interval, as needed. 
30 
List of Fruiting Vegetables: African Eggplant, Bell Pepper, Eggplant, Martynia, Non-Bell 
Pepper, Okra, Pea Eggplant, Pepino, Roselle, Scarlet Eggplant, and cultivars, varieties 
and/or hybrids of these crops. 
Restrictions: 
• No single application may exceed 14 fl oz of product (0.114 lb ai)/A. 
• Do not apply more than 4 applications per year. 
• Do not apply more than 56 fl oz of product (0.455 lb ai)/A per year. 
• Do not apply more than 0.455 lb ai of flutriafol/A per year. 
• Restricted Entry Interval (REI) is 12 hours. 
• Preharvest Interval (PHI): May be applied the day of harvest (0 day PHI).

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
 25 
Use Directions for Pome Fruit (Apple, Crabapple, Loquat, Mayhaw, Pear, Oriental 
Pear, and Quince) 
[Not for use in CA] 
 
Diseases Product 
Rate 
(fl oz/A) 
Application Directions Application 
Interval 
(Days) 
Powdery Mildew 
 (Podosphaera leucotricha) 
 
Quince Rust 
 (Gymnosporangium clavipes) 
 
Cedar Apple Rust 
 (Gymnosporangium 
 juniperi-virginianae) 
 
Brooks Fruit Spot 
(Mycosphaerella pomi) 
 
Flyspeck 
(Zygophiala jamacaicensis) 
 (formerly Schizothyrium 
pomi)
 
 
8 - 12 
 
(0.065-
0.098 lb 
ai/A) 
Initiate applications at 
green tip and continue 
through cover sprays. 
 
 
10

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
 26 
Apple Scab 
 (Venturia inaequalis) 
 
Sooty Blotch 
(Gloeodes pomigena) 
 
Bot rot or White rot 
(Botryosphaeria dothidea) 
 
Black Rot 
(Botryosphareia obtusa) 
 
Bitter Rot 
(Colletotrichum 
gloeosporioides, C. 
acutatum) 
 
Alternaria Blotch 
(Alternaria mali) 
 
 
13 
 
(0.106 lb 
ai/A) 
Initiate applications at 
green tip or when 
environmental conditions 
are favorable for primary 
scab development. 
Continue applications 
through the duration of 
primary scab. 
 
Mix TOPGUARD Fungicide 
with a protectant such as 
KOVERALL Fungicide 
(mancozeb) or captan 
fungicide for scab control. 
 
Tank mix applications 
containing TOPGUARD 
Fungicide with a protectant 
such as KOVERALL 
Fungicide (mancozeb) or 
captan fungicide will also 
effectively control listed 
summer rots when applied 
at cover spray timings. 
7 - 10 
 
Pear Scab 
 (Venturia pirina) 
13 
 
(0.106 lb 
ai/A) 
Start application at Pink 
Bud and continue through 
the duration of the Primary 
Scab period. 
 
Mix TOPGUARD Fungicide 
with a protectant such as 
KOVERALL Fungicide or 
captan fungicide for 
improved scab control. 
7 - 10 
 
 
Restrictions: 
• No single application may exceed 13 fl oz of product (0.106 lb ai)/A. 
• Do not apply more than 4 applications per year. 
• Do not apply more than 52 fl oz of product (0.423 lb ai)/A per year. 
• Do not apply more than 0.423 lb ai of flutriafol/A per year. 
• Restricted Entry Interval (REI) is 12 hours. 
• Preharvest Interval (PHI): Do not apply within 14 days of harvest.

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
 27 
Use Directions for Grain Sorghum 
[Not for use in CA] 
 
Diseases Product 
Rate 
(fl.oz./A) 
Application Directions Application 
Interval 
(Days) 
Anthracnose Leaf Blight 
 (Colletotrichum graminicola) 
 
Ergot 
 (Claviceps sorghi) 
 
Gray Leaf Spot 
 (Cercospora sorghi) 
 
Leaf Blight 
 (Exserohilum turcicum or 
 Setosphaeria turcica) 
 
Rust, Common 
 (Puccinia purpuria 
 
Ladder Leaf Spot 
 (Cercospora fusimaculans) 
 
Rough Spot 
 (Ascochyta sorghi) 
 
Sooty Stripe 
 (Ramulispora sorghi) 
 
Target Leaf Spot 
 (Bipolaris cookei) 
 
Zonate Leaf Spot and Sheath 
Blight 
 (Gloecercospora sorghi) 
7 - 14 
 
(0.057-
0.114 lb 
ai/A) 
For Ergot make first 
application at, or just prior 
to, flowering. 
 
For all other diseases 
apply preventatively or 
when conditions are 
favorable for disease 
development. Repeat as 
necessary if conditions are 
favorable for disease 
development. 
7 
Restrictions: 
• No single application may exceed 14 fl oz of product (0.114 lb ai)/A. 
• Do not apply more than 2 applications per year. 
• Do not apply more than 28 fl oz of product (0.228 lb ai)/A per year. 
• Do not apply more than 0.228 lb ai of flutriafol/A per year. 
• Restricted Entry Interval (REI) is 12 hours. 
• Preharvest Interva (PHI)l: Do not apply within 30 days of harvest for stover, 
forage or grain.

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
 28 
Use Directions for Soybean (Foliar Applications) 
[Not for use in CA] 
 
Diseases Product 
Rate 
(fl oz/A) 
Application Directions Application 
Interval 
(Days) 
Cercospora Leaf Blight and 
Purple Seed Stain 
 (Cercospora kikuchii) 
 
Frogeye Leaf Spot 
 (Cercospora sojina) 
 
Brown Spot 
 (Septoria glycines) 
 
Powdery Mildew 
 (Microsphaera diffusa) 
 
Target Spot 
 (Corynespora cassiicola) 
 
Suppression: 
White Mold / Stem Rot 
 (Sclerotinia sclerotiorum) 
 
Southern Blight 
 (Sclerotium rolfsii) 
7 -14 
 
(0.057-
0.114 lb 
ai/A) 
For Cercospora Leaf Blight begin 
applications at first flower (R1). 
 
For other diseases apply 
beginning at first visible flower or 
when conditions are favorable for 
disease development. 
 
Apply additional applications if 
environmental conditions are 
favorable for continued disease 
development. 
 
 
14 – 35 
 
 
Rust 
 (Phakopsora pachyrhizi) 
7 - 14 
 
(0.057-
0.114 lb 
ai/A) 
Apply beginning at first visible 
flower or when conditions are 
favorable for disease 
development. 
 
Apply additional applications if 
environmental conditions are 
favorable for continued disease 
development. 
21 – 35

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
 29 
[Use Directions for Soybean (Foliar Applications) (continued)] 
 
Restrictions: 
• No single at-planting application may exceed 32 fl oz of product (0.26 lb ai)/A. 
• No single foliar application may exceed 14 fl oz of product (0.114 lb ai)/A. 
• Do not apply more than 3 foliar applications per year. 
• Do not apply more than 1 at-planting application per year. 
• For foliar applications: Two foliar applications can be made at 14 fl. oz. of product 
(0.114 lb ai)/A – OR - One foliar application at 14 fl oz of product (0.114 lb ai)/A 
followed by two additional foliar applications at 7 fl oz of product (0.057 lb ai)/A. 
• Do not apply more than 60 fl oz of product (0.488 lb ai)/A per year. 
• Do not apply more than 0.488 lb ai of flutriafol/A per year (including soil and foliar 
applications) 
• Restricted Entry Interval (REI) is 12 hours. 
• Do not feed forage or hay to animals or permit animals to graze. 
• Preharvest Interval (PHI): Do not apply within 21 days of harvest.

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
 30 
Use Directions for Soybean (At Planting Applications) 
[Not for use in CA] 
 
Suppression of Soilborne 
Diseases: 
 
Sudden Death Syndrome 
 (Fusarium solani f. sp. 
 glycines, F. virguliforme) 
 
Charcoal Rot 
 (Macrophomina 
 phaseolina) 
 
 
16 - 32 
 
(0.13-
0.26 lb 
ai/A) 
 
See table below for rate chart 
depending on row width. 
 
Apply in 3 to 6 gallons of water 
per acre at planting. 
 
Methods of application: 
T-Band Application: Apply 
TOPGUARD Fungicide in a 
concentrated 3-4 inch wide band 
at planting with the spray tip 
oriented perpendicular to the row 
direction and with spray tip 
located after furrow opening and 
seed placement but prior to 
furrow closure with press wheel. 
 
In-Furrow / Modified In-Furrow 
Application: Apply in furrow 
using a mechanism that guides 
the product so as not to come 
into direct contact with the seed. 
 
Temporary soybean height 
reductions are sometimes noted 
when TOPGUARD is applied in-
furrow or by and T-band 
applications. The height 
reduction is temporary and 
soybeans will recover over a 
period of 2 to 3 weeks.

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
 31 
[Use Directions for Soybean (At Planting applications) (continued)] 
 
Restrictions: 
• No single at-planting application may exceed 32 fl oz of product (0.26 lb ai)/A. 
• No single foliar application may exceed 14 fl oz of product (0.114 lb ai)/A. 
• Do not apply more than 3 foliar applications per year. 
• Do not apply more than 1 at-planting application per year. 
• For foliar applications: Two foliar applications can be made at 14 fl oz of product 
(0.114 lb ai)/A – OR - One foliar application at 14 fl oz of product (0.114 lb ai)/A 
followed by two additional foliar applications at 7 fl oz of product (0.057 lb ai)/A. 
• Do not apply more than 60 fl oz of product (0.488 lb ai)/A per year. 
• Do not apply more than 0.488 lb ai of flutriafol/A per year (including soil and foliar 
applications) 
• Restricted Entry Interval (REI) is 12 hours. 
• Do not feed forage or hay to animals or permit animals to graze. 
• Preharvest Interval (PHI): Do not apply within 21 days of harvest. 
 
 
 
 
 
 
Rate Chart: Product Rate Depending on Row Width 
Row Spacing (inches) 
fl oz of TOPGUARD/1000 ft of Row 
16 fl oz/A Rate 32 fl oz/A Rate 
20 0.67 1.35 
30 0.92 1.84 
32 0.98 1.96 
36 1.10 2.20 
38 1.16 2.32 
40 1.22 2.45 
20” = 23,760 row ft./A; 30” = 17,424 row ft./A; 32” = 16,315 row ft./A; 34” = 15,374 row ft./A; 36” = 14,520 
row ft./A; 38” = 13,754 row ft./A; 40” = 13,068 row ft./A. 
 
Formula: Selected Use Rate (fl oz/A) = fl oz of product to be applied per 1000 row ft. 
 [Row ft for row spacing/1000 ft] 
 
Example of 30” row spacing at 16 fl oz/A: 
 16 fl. oz/A = 0.92 fl oz of product to be applied per 1000 row ft. 
 [17,424/1000]

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
 32 
Use Directions for Stone Fruit (See below for a list of crops.) 
[Optional language: Use Directions for Cherry (Sweet and Tart)] 
[Not for use in CA] 
 
Diseases Product 
Rate 
(fl oz/A) 
Application Directions Application 
Interval 
(Days) 
Powdery Mildew 
 (Podosphaera clandestina) 
 
14 
 
(0.114 lb 
ai/A) 
Start applications at petal 
fall. Repeat as necessary if 
disease conditions are 
favorable for disease 
development. 
7 
 
Brown Rot Blossom Blight 
 (Monilinia fructicola) 
14 
 
(0.114 lb 
ai/A) 
Start applications at 1-5% 
bloom followed by an 
application at 50-100 % 
bloom. 
7 
 
Fruit Brown Rot 
 (Monilinia fructicola) 
 
14 
 
(0.114 lb 
ai/A) 
Apply one to two weeks 
prior to harvest. 
 
7 
 
Cherry Leaf Spot 
 (Blumeriella jaapii) 
 
14 
 
(0.114 lb 
ai/A) 
 
Start applications at petal 
fall. Repeat as necessary if 
disease conditions are 
favorable for disease 
development. 
 
In areas of known triazole 
resistance, apply 
TOPGUARD Fungicide with 
a protectant fungicide for 
control. 
7 
 
List of Stone Fruit: Apricot, Nectarine, Sweet Cherry, Tart Cherry, Peach, Plum, 
Chicksaw Plum, Damson Plum, Japanese Plum, Plumcot, Prune. 
 
Restrictions: 
• No single application may exceed 14 fl oz of product (0.114 lb ai)/A. 
• Do not apply more than 4 applications per year. 
• Do not apply more than 56 fl oz of product (0.455 lb ai)/A per year. 
• Do not apply more than 0.455 lb ai of flutriafol/A per year. 
• Restricted Entry Interval (REI) is 12 hours. 
• Preharvest Interval (PHI): Do not apply within 7 days of harvest.

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
 33 
Use Directions for Sugar Beet 
[Not for use in CA] 
 
Diseases Product 
Rate 
(fl oz/A) 
Application Directions Application 
Interval 
(Days) 
Cercospora Leaf Spot 
 (Cercospora beticola) 
 
 
10 - 14 
 
(0.081-
0.114 lb 
ai/A) 
Apply preventatively or when 
conditions are favorable for disease 
development. Repeat as necessary 
if conditions are favorable for 
disease development. 
 
Tank mix with KOVERALL 
Fungicide (mancozeb) for resistance 
management. 
14 
 
Powdery Mildew 
 (Erysiphe betae) 
10 - 14 
 
(0.081-
0.114 lb 
ai/A) 
Apply preventatively or when 
conditions are favorable for disease 
development. Repeat as necessary 
if conditions are favorable for 
disease development. 
14 
 
Restrictions: 
• No single application may exceed 14 fl oz of product (0.114 lb ai)/A. 
• Do not apply more than 2 applications per year. 
• Do not apply more than 28 fl oz of product (0.228 lb ai)/A per year. 
• Do not apply more than 0.228 lb ai of flutriafol/A per year. 
• Restricted Entry Interval (REI) is 12 hours. 
• Preharvest Interval (PHI): Do not apply within 21 days of harvest.

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
 34 
Use Directions for Wheat (Spring and Winter), Barley, and Triticale 
[Not for use in CA] 
 
Diseases Product 
Rate 
(floz/A) 
Application Directions Application 
Interval 
(Days) 
Rust 
 (Puccina spp.) 
 
Powdery Mildew 
 (Blumeria graminis) 
 
Leaf and Glume Blotch 
 (Septoria spp.) 
10 - 14 
 
(0.081-
0.114 lb 
ai/A) 
Apply preventatively or 
when conditions are 
favorable for disease 
development. Repeat as 
necessary if conditions are 
favorable for disease 
development. 
 
For aerial application, use 
a minimum of 2 gallons of 
spray solution per acre. 
 
7 
Suppression: 
Fusarium Head Blight 
 (Fusarium spp.) 
10 - 14 
 
(0.081-
0.114 lb 
ai/A) 
Apply at anthesis (Feekes 
Growth Stage 10.51). 
Spray equipment nozzles 
should be properly set up to 
ensure good coverage of 
the head. 
 
For aerial application, use 
a minimum of 2 gallons of 
spray solution per acre. 
 
7 
Restrictions: 
• No single application may exceed 14 fl oz of product (0.114 lb ai)/A. 
• Do not apply more than 2 applications per year. 
• Do not apply more than 28 fl oz of product (0.228 lb ai)/A per year. 
• Do not apply more than 0.228 lb ai of flutriafol/A per year. 
• Restricted Entry Interval (REI) is 12 hours. 
• Preharvest Interval (PHI): Do not apply within 30 days of harvest when grown for 
grain, 15 days of harvest grown for hay, zero (0) day PHI when grown for forage.

Topguard Fungicide [Optional text appears in brackets] 
EPA Reg. No. 279-3557 
 
 
 
 35 
CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY 
 
NOTICE: Read the entire Directions for Use and Conditions of Sale and Limitation of 
Warranty and Liability before buying or using this product. If the terms are not 
acceptable, return the product at once, unopened, and the purchase price will be 
refunded. 
 
The Directions for Use of this product must be followed carefully. It is impossible to 
eliminate all risks inherently associated with the use of this product. Crop injury, 
ineffectiveness, or other unintended consequences may result because of such factors 
as manner of use or application, weather or crop conditions beyond the control or FMC 
or Seller. All such risks shall be assumed by Buyer and User, and Buyer and User 
agree to hold FMC and Seller harmless for any claims relating to such factors. 
 
Seller warrants that this product conforms to the chemical description on the label and is 
reasonably fit for the purposes stated on the Directions for Use when used in 
accordance with the directions under normal conditions of use. To the extent consistent 
with applicable law, FMC MAKES NO WARRANTIES OF MERCHANTABILITY OR OF 
FITNESS FOR A PARTICULAR PURPOSE, NOR ANY OTHER EXPRESS OR 
IMPLIED WARRANTIES WITH RESPECT TO THE SELECTION, PURCHASE, OR 
USE OF THIS PRODUCT. Any warranties, express or implied, having been made are 
inapplicable if this product has been used contrary to label instructions, or under 
abnormal conditions, or under conditions not reasonably foreseeable to (or beyond the 
control of) seller or FMC, and buyer assumes the risk of any such use. 
 
To the extent consistent with applicable law, FMC or seller shall not be liable for any 
incidental, consequential or special damages resulting from the use or handling of this 
product. 
 
To the extent consistent with applicable law, THE EXCLUSIVE REMEDY OF THE 
USER OR BUYER, AND THE EXCLUSIVE LIABILITY OF FMC AND SELLER FOR 
ANY AND ALL CLAIMS, LOSSES, INJURIES OR DAMAGES (INCLUDING CLAIMS 
BASED ON BREACH OF WARRANTY, CONTRACT, NEGLIGENCE, TORT, STRICT 
LIABILITY OR OTHERWISE) RESULTING FROM THE USE OR HANDLING OF THIS 
PRODUCT, SHALL BE THE RETURN OF THE PURCHASE PRICE OF THE 
PRODUCT OR, AT THE ELECTION OF FMC OR SELLER, THE REPLACEMENT OF 
THE PRODUCT. 
 
This Conditions of Sale and Limitation of Warranty and Liability may not be amended by 
any oral or written agreement. 
 
TOPGUARD
® and Koverall® are registered trademarks of FMC 
 
 
Label code: SL-4367-1 030920 052422 02-21-20