crop-chem-docs/corpus/epa_ppls/352-873.md

# INSTIGATE

- EPA Reg No: **352-873**
- Registrant: CORTEVA AGRISCIENCE, LLC
- Signal word: Caution
- Active ingredients: Mesotrione (41.67%); Rimsulfuron (4.17%)
- Label accepted: 2023-05-30
- Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000352-00873-20230530.pdf

---
UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 
 WASHINGTON, DC 20460 
OFFICE OF CHEMICAL SAFETY 
AND POLLUTION PREVENTION 
 
Notification ABN or Label Acceptable v.20220527 
May 30, 2023 
 
 
Wes Marchione 
Regulatory Leader – Regulatory Affairs 
Corteva Agriscience 
9330 Zionsville Road 
Indianapolis, IN 46268 
 
Subject: Notification per PRN 98-10 – Update primary and alternate brand names, 
company details, and warranty statement 
 Product Name: Instigate 
 EPA Registration Number: 352-873 
 Application Date: 03/27/2023 
 Decision Number: 591683 
 
Dear Wes Marchione: 
 
The Agency is in receipt of your Application for Pesticide Notification under Pesticide 
Registration Notice (PRN) 98-10 for the above referenced product. The Registration Division 
(RD) has conducted a review of this request for its applicability under PRN 98-10 and finds that 
the action requested falls within the scope of PRN 98-10. 
 
The label submitted with the application has been stamped “NOTIFICATION” and placed in our 
records. 
 
The alternate brand name, “DuPont Instigate” has been added to the product record. 
 
Should you wish to add/retain a reference to the company’s website on your label, then please be 
aware that the website becomes labeling under the Federal Insecticide, Fungicide, and 
Rodenticide Act (FIFRA) and is subject to review by the Agency. If the website is false or 
misleading, the product would be misbranded and unlawful to sell or distribute under FIFRA 
section 12(a)(1)(E). 40 CFR 156.10(a)(5) lists examples of statements EPA may consider false or 
misleading. In addition, regardless of whether a website is referenced on your product’s label, 
claims made on the website may not substantially differ from those claims approved through the 
registration process. Therefore, should the Agency find or if it is brought to our attention that a 
website contains false or misleading statements or claims substantially differing from the EPA 
approved registration, the website will be referred to the EPA’s Office of Enforcement and 
Compliance.

Page 2 of 2 
EPA Reg. No. 352-873 
Decision No. 591683 
 
If you have any questions, please contact Jennifer Drobish at 202-566-2642 or at 
Drobish.jennifer@epa.gov. 
 
 
Sincerely, 
 
 
 
Aswathy Balan 
Senior Regulatory Specialist 
Fungicide and Herbicide Branch 
Registration Division 
Office of Pesticide Programs

Q2M / Instigate® / MSTR /Notification with edits / 11-21-22 Page 1 
(Base label): 
RIMSULFURON GROUP 2 HERBICIDE 
MESOTRIONE GROUP 27 HERBICIDE 
DuPont™ Instigate®
HERBIDIDE 
[Alternate Brand Name: DuPont Instigate®] 
HERBIDCIDE 
For use in field corn grown for grain or silage 
Active Ingredients 
Rimsulfuron 
N-((4,6-dimethoxypyrimidin-2-yl)aminocarbonyl)-3-(ethylsulfonyl)- 
2-pyridinesulfonamide………………………………………………………………………... 4.17% 
Mesotrione………………………………………………………………………………………… 41.67% 
Other In
gredients………………………………………………………………………………… 54.16% 
TOTAL…………………………………………………………………………………………….. 100.00% 
Contains 0.0417 lb of rimsulfuron and 0.4167 lb of mesotrione active ingredient per pound of product. 
Keep Out of Reach of Children 
CAUTION 
Si usted no entiende la etiqueta, busque a alguien para que se la explique a usted en detalle. (If you do 
not understand this label, find someone to explain it to you in detail.) 
_____________________________________________________________________ 
Precautionary Statements_______________________________________________ 
Hazards To Humans And Domestic Animals 
Causes moderate eye irritation. Avoid contact with eyes, skin or clothing. 
Personal Protective Equipment (PPE) 
Applicators and other handlers must wear: 
x Long-sleeve shirt and long pants. 
x Chemical resistant gloves made of any waterproof material including butyl rubber, natural rubber, 
neoprene rubber, or nitrile rubber. 
x Shoes plus socks. 
Follow manufacturer's instructions for cleaning/maintaining PPE. If no such instructions for washables 
exist, use detergent and hot water. Keep and wash PPE separately from other laundry. 
Engineering Control Statements 
When handlers use closed systems or enclosed cabs in a manner that meets the requirements listed in 
the Worker Protection Standard (WPS) for agricultural pesticides [40 CFR 170.240(d)(4-6)], the handler 
PPE requirements may be reduced or modified as specified in the WPS. 
352-873
05/30/2023

Q2M / Instigate® / MSTR /Notification with edits / 11-21-22 Page 2 
 
User Safety Recommendations 
USERS SHOULD: 
x Wash hands before eating, drinking, chewing gum, using tobacco or using the toilet. 
x Remove PPE immediately after handling this product. 
x Wash the outside of gloves before removing. 
x As soon as possible, wash thoroughly and change into clean clothing. 
x Remove clothing/PPE immediately if pesticide gets inside. 
x Then wash thoroughly and put on clean clothing.
 
First Aid 
x IF IN EYES: Hold eye open and rinse slowly and gently with water for 15-20 minutes. Remove 
contact lenses, if present, after the first 5 minutes, then continue rinsing eye. Call a poison control 
center or doctor for treatment advice. 
x IF ON SKIN OR CLOTHING: Take off contaminated clothing. Rinse skin immediately with plenty of 
water for 15-20 minutes. Call a poison control center or doctor for treatment advice. 
x IF SWALLOWED: Call a poison control center or doctor immediately for treatment advice. Have 
person sip a glass of water if able to swallow. DO NOT induce vomiting unless told to by a poison 
control center or doctor. DO NOT give anything to an unconscious person. 
x IF INHALED: Move person to fresh air. If person is not breathing, call 911 or an ambulance, then 
give artificial respiration, preferably by mouth-to-mouth, if possible. Call a poison control center or 
doctor for further treatment advice. 
 
Have the product container or label with you when calling a poison control center or doctor, or going for 
treatment. You may also contact 1-800-441-3637992-5994 for emergency medical treatment 
information. 
 
Environmental Hazards 
DO NOT apply directly to water, or to areas where surface water is present or to intertidal areas below the 
mean high water mark. DO NOT contaminate water when disposing of equipment wash water or rinsate. 
 
Surface Water Label Advisory 
 
This product may impact surface water quality due to runoff of rain water. This is especially true for poorly 
draining soils and soils with shallow ground water. This product is classified as having high potential for 
reaching surface water via runoff for several months or more after application. A level, well-maintained 
vegetative buffer strip between areas to which this product is applied and surface water features such as 
ponds, streams, and springs will reduce the potential loading of rimsulfuron from runoff water and 
sediment. Runoff of this product will be greatly reduced by avoiding applications when rainfall or irrigation 
is expected to occur within 48 hours. 
 
Windblown Soil Particles 
 
This product has the potential to move off-site due to wind erosion. Soils that are subject to wind erosion 
usually have a high silt and/or fine to very fine sand fractions and low organic matter content. Other 
factors which can affects the movement of windblown soil include the intensity and direction of prevailing 
winds, vegetative cover, site slope, rainfall, and drainage patterns. Avoid applying this product if 
prevailing local conditions may be expected to result in off-site movement. 
 
Non-target Organism Advisory 
 
This product is toxic to plants and may adversely impact the forage and habitat of non-target organisms, 
including pollinators, in areas adjacent to the treated area. Protect the forage and habitat of non-target 
organisms by minimizing spray drift. For further guidance and instructions on how to minimize spray drift, 
refer to the Spray Drift Management section of this label.

Q2M / Instigate® / MSTR /Notification with edits / 11-21-22 Page 3 
 
 
 
 Agricultural Use Requirements 
Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR 
Part 170. Refer to the label booklet under "Agricultural Use Requirements" in the Directions for Use 
section for information about this standard.
 
Nonrefillable Plastic and Metal Containers (Capacity Equal to or Less Than 50 Pounds): 
Storage and Disposal 
DO NOT contaminate water, food or feed by storage and disposal. 
Pesticide Storage: Store product in original container only. Store in a cool, dry place. 
Product Disposal: Waste resulting from the use of this product must be disposed of on site or at an 
approved waste disposal facility. 
Container Disposal: Nonrefillable container. DO NOT reuse or refill this container. Triple rinse 
container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents 
into application equipment or a mix tank. Fill the container 1/4 full with water and recap. Shake for 10 
seconds. Pour rinsate into application equipment or a mix tank or store rinsate for later use or disposal. 
Drain for 10 seconds after the flow begins to drip. Repeat this procedure two more times. Then, for 
Plastic Containers, offer for recycling if available or puncture and dispose of in a sanitary landfill, or by 
incineration. DO NOT burn, unless allowed by state and local ordinances. For Metal Containers, offer 
for recycling if available or reconditioning if appropriate, or puncture and dispose of in a sanitary landfill, 
or b
y other procedures approved by state and local authorities. 
 
Nonrefillable Plastic and Metal Containers (Capacity Greater Than 50 Pounds): 
Storage and Disposal 
DO NOT contaminate water, food or feed by storage and disposal. 
Pesticide Storage: Store product in original container only. Store in a cool, dry place. 
Product Disposal: Waste resulting from the use of this product must be disposed of on site or at an 
approved waste disposal facility. 
Container Disposal: Nonrefillable container. DO NOT reuse or refill this container. Triple rinse 
container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents 
into application equipment or a mix tank. Fill the container 1/4 full with water. Replace and tighten 
closures. Tip container on its side and roll it back and forth, ensuring at least one complete revolution, 
for 30 seconds. Stand the container on its end and tip it back and forth several times. Turn the 
container over onto its other end and tip it back and forth several times. Empty the rinsate into 
application equipment or a mix tank or store rinsate for later use or disposal. Repeat this procedure two 
more times. Then, for Plastic Containers, offer for recycling if available or puncture and dispose of in a 
sanitary landfill, or by incineration. DO NOT burn, unless allowed by state and local ordinances. For 
Metal Containers, offer for recycling if available or reconditioning if appropriate, or puncture and 
dispose of in a sanitar
y landfill, or by other procedures approved by state and local authorities 
 
Nonrefillable Plastic and Metal Containers, e.g., Intermediate Bulk Containers [IBC] (Size or Shape 
Too Large to be Tipped, Rolled or Turned Upside Down): 
Storage and Disposal 
DO NOT contaminate water, food or feed by storage and disposal. 
Pesticide Storage: Store product in original container only. Store in a cool, dry place. 
Product Disposal: Waste resulting from the use of this product must be disposed of on site or at an 
approved waste disposal facility. 
Container Disposal: Nonrefillable container. DO NOT reuse or refill this container. Clean container 
promptly after emptying the contents from this container into application equipment or mix tank and 
before final disposal using the following pressure rinsing procedure. Insert a lance fitted with a suitable 
tank cleaning nozzle into the container and ensure that the water spray thoroughly covers the top, 
bottom and all sides inside the container. The nozzle manufacturer generally provides instructions for 
the appropriate spray pressure, spray duration and/or spray volume. If the manufacturer’s instructions 
are not available, pressure rinse the container for at least 60 seconds usin
g a minimum pressure of 30

Q2M / Instigate® / MSTR /Notification with edits / 11-21-22 Page 4 
 
PSI with a minimum rinse volume of 10% of the container volume. Drain, pour or pump rinsate into 
application equipment or rinsate collection system. Repeat this pressure rinsing procedure two more 
times. Then, for Plastic Containers, offer for recycling if available or puncture and dispose of in a 
sanitary landfill, or by incineration. For Metal Containers, offer for recycling if available or reconditioning 
if appropriate, or puncture and dispose of in a sanitary landfill, or by other procedures approved by 
state and local authorities. 
 
Nonrefillable Paper or Plastic Bags, Fiber Sacks including Flexible Intermediate Bulk Containers 
(FIBC) or Fiber Drums With Liners: 
Storage and Disposal 
DO NOT contaminate water, food or feed by storage and disposal. 
Pesticide Storage: Store product in original container only. Store in a cool, dry place. 
Product Disposal: Waste resulting from the use of this product must be disposed of on site or at an 
approved waste disposal facility. 
Container Disposal: Nonrefillable container. DO NOT reuse or refill this container. Completely empty 
paper or plastic bag, fiber sack or drum liner by shaking and tapping sides and bottom to loosen 
clinging particles. Empty residue into application or manufacturing equipment. Then offer for recycling if 
available or dispose of empty paper or plastic bag, fiber sack or fiber drum and liner in a sanitary 
landfill, or by incineration. DO NOT burn, unless allowed by state and local ordinances. 
 
Refillable Fiber Drums With Liners: 
Storage and Disposal 
DO NOT contaminate water, food or feed by storage and disposal. 
Pesticide Storage: Store product in original container only. Store in a cool, dry place. 
Product Disposal: Waste resulting from the use of this product must be disposed of on site or at an 
approved waste disposal facility. 
Refillable container (fiber drum only). Refilling Fiber Drum: Refill this fiber drum with DuPont Instigate® 
herbicide containing rimsulfuron and mesotrione only. DO NOT reuse this fiber drum for any other 
purpose. Cleaning before refilling is the responsibility of the refiller. Completely empty liner by shaking 
and tapping sides and bottom to loosen clinging particles. Empty residue into application or 
manufacturing equipment. Disposing of Fiber Drum and/or Liner: DO NOT reuse this fiber drum for any 
other purpose other than refilling (see preceding). Cleaning the container (liner and/or fiber drum) 
before final disposal is the responsibility of the person disposing of the container. Offer the liner for 
recycling if available or dispose of liner in a sanitary landfill, or by incineration. DO NOT burn, unless 
allowed by state and local ordinances. If drum is contaminated and cannot be reused, dispose of it in 
the manner required for its liner. To clean the fiber drum before final disposal, completely empty the 
fiber drum by shaking and tapping sides and bottom to loosen clinging particles. Empty residue into 
application or manufacturing equipment. Then offer the fiber drum for recycling if available or dispose 
of in a sanitar
y landfill, or by incineration. DO NOT burn, unless allowed by state and local ordinances. 
 
All Other Refillable Containers: 
Storage and Disposal 
DO NOT contaminate water, food or feed by storage and disposal. 
Pesticide Storage: Store product in original container only. Store in a cool, dry place. 
Product Disposal: Waste resulting from the use of this product must be disposed of on site or at an 
approved waste disposal facility. 
Container Disposal: Refer to the Net Contents section of this product’s labeling for the 
applicable “Refillable Container” or “Nonrefillable Container” designation. 
All Other Refillable Containers: Refillable container. Refilling Container: Refill this container with 
DuPont Instigate containing rimsulfuron and mesotrione only. DO NOT reuse this container for any 
other purpose. Cleaning before refilling is the responsibility of the refiller. Prior to refilling, inspect 
carefully for damage such as cracks, punctures, abrasions, worn out threads and closure devices. If 
damage is found, DO NOT use the container, contact DuPont Corteva Agriscience at the number 
below for instructions. Check for leaks after refilling and before transporting. If leaks are found, DO 
NOT reuse or transport container, contact DuPont Corteva Agriscience at the number below for

Q2M / Instigate® / MSTR /Notification with edits / 11-21-22 Page 5 
 
instructions. Disposing of Container: DO NOT reuse this container for any other purpose other than 
refilling (see preceding). Cleaning the container before final disposal is the responsibility of the person 
disposing of the container. To clean the container before final disposal, use the following pressure 
rinsing procedure. Insert a lance fitted with a suitable tank cleaning nozzle into the container and 
ensure that the water spray thoroughly covers the top, bottom and all sides inside the container. The 
nozzle manufacturer generally provides instructions for the appropriate spray pressure, spray duration 
and/or spray volume. If the manufacturer’s instructions are not available, pressure rinse the container 
for at least 60 seconds using a minimum pressure of 30 PSI with a minimum rinse volume of 10% of 
the container volume. Drain, pour or pump rinsate into application equipment or rinsate collection 
system. Repeat this pressure rinsing procedure two more times. Then, for Plastic Containers, offer for 
recycling if available or puncture and dispose of in a sanitary landfill, or by incineration. DO NOT burn, 
unless allowed by state and local ordinances. For Metal Containers, offer for recycling if available or 
reconditioning if appropriate, or puncture and dispose of in a sanitary landfill, or by other procedures 
approved b
y state and local authorities. 
 
Outer Foil Pouches of Water Soluble Packets (WSP): 
Storage and Disposal 
DO NOT contaminate water, food or feed by storage and disposal. 
Pesticide Storage: Store product in original container only. Store in a cool, dry place. 
Product Disposal: Waste resulting from the use of this product must be disposed of on site or at an 
approved waste disposal facility. 
Container Disposal: Nonrefillable container. DO NOT reuse or refill this container. Offer for recycling if 
available or, dispose of the empty outer foil pouch in the trash as long as WSP is unbroken. If the outer 
pouch contacts the formulated product in any way, the pouch must be triple rinsed with clean water. 
Add the rinsate to the spray tank and dispose of the outer pouch as described previously. 
 
DO NOT transport if this container is damaged or leaking. If the container is damaged, leaking or 
obsolete, or in the event of a major spill, fire or other emergency, contact DuPont Corteva Agriscience at 
1-800-441-3637992-5994, day or night. 
 
Refer to inside of label booklet for additional precautionary information and Directions for Use. 
 
Notice: Read the entire label. Use only according to label directions. Before using this product, read 
Warranty Disclaimer, Inherent Risks of Use and Limitation of Remedies at end of label booklet. If 
terms are unacceptable, return at once unopened. 
 
In case of emergency endangering health or the environment involving this product, call 1-800-441-
3637992-5994. 
 
Agricultural Chemical: DO NOT ship or store with food, feeds, drugs, or clothing. 
 
EPA Reg. No. 352-873 EPA Est. _______ 
 
™®Trademarks of Corteva Agriscience and its affiliated companies 
®™ Trademarks of Dow AgroSciences, DuPont or Pioneer and their affiliated companies or respective owners 
 
Produced for 
Corteva Agriscience LLC 
9330 Zionsville Road 
Indianapolis, IN 46268 
Produced for 
E.I du Pont de Nemours & Company 
Chestnut Run Plaza 
974 Centre Road 
Wilmington, DE 19805

Q2M / Instigate® / MSTR /Notification with edits / 11-21-22 Page 6 
 
 
NET_____

Q2M / Instigate® / MSTR /Notification with edits / 11-21-22 Page 7 
 
(Cover/Shipping Container): 
RIMSULFURON GROUP 2 HERBICIDE 
MESOTRIONE GROUP 27 HERBICIDE 
DuPont™ Instigate® 
HERBIDIDE 
[Alternate Brand Name: DuPont Instigate®] 
 
HERBIDCIDE 
 
For use in field corn grown for grain or silage 
 
Active Ingredients 
Rimsulfuron 
N-((4,6-dimethoxypyrimidin-2-yl)aminocarbonyl)-3-(ethylsulfonyl)- 
2-p
yridinesulfonamide………………………………………………………………………... 4.17% 
Mesotrione………………………………………………………………………………………… 41.67% 
Other Ingredients………………………………………………………………………………… 54.16% 
TOTAL…………………………………………………………………………………………….. 100.00% 
 
Contains 0.0417 lb of rimsulfuron and 0.4167 lb of mesotrione active ingredient per pound of product. 
 
Keep Out of Reach of Children 
CAUTION 
 
Si usted no entiende la etiqueta, busque a alguien para que se la explique a usted en detalle. (If you do 
not understand this label, find someone to explain it to you in detail.) 
 
 Agricultural Use Requirements 
Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR 
Part 170. Refer to the label booklet under "Agricultural Use Requirements" in the Directions for Use 
section for information about this standard.
 
Refer to inside of label booklet for additional precautionary information and Directions for Use. 
 
Notice: Read the entire label. Use only according to label directions. Before using this product, read 
Warranty Disclaimer, Inherent Risks of Use and Limitation of Remedies at end of label booklet. If 
terms are unacceptable, return at once unopened. 
 
In case of emergency endangering health or the environment involving this product, call 1-800-441-
3637992-5994. 
 
Agricultural Chemical: DO NOT ship or store with food, feeds, drugs, or clothing. 
 
EPA Reg. No. 352-873 EPA Est. _______ 
 
™
®Trademarks of Corteva Agriscience and its affiliated companies 
®™ Trademarks of Dow AgroSciences, DuPont or Pioneer and their affiliated companies or respective owners 
 
Produced for 
Corteva Agriscience LLC 
9330 Zionsville Road 
Indianapolis, IN 46268 
Produced for

Q2M / Instigate® / MSTR /Notification with edits / 11-21-22 Page 8 
 
E.I du Pont de Nemours & Company 
Chestnut Run Plaza 
974 Centre Road 
Wilmington, DE 19805 
NET: _______

Q2M / Instigate® / MSTR /Notification with edits / 11-21-22 Page 9 
(Page 1 through end) 
 Precautionary Statements 
Hazards to Humans and Domestic Animals 
CAUTION
Causes moderate eye irritation. Avoid 
contact with eyes, skin or clothing. 
Personal Protective Equipment (PPE) 
Applica
tors and other handlers must wear: 
x Long-sleeve shirt and long pants. 
x Chemical resistant gloves made of any waterproof material including butyl rubber, natural rubber, 
neoprene rubber, ornitrilerubber. 
x Shoes plus socks. 
Follow manufacturer's instructions for cleaning/maintaining PPE. If no such instructions for washables 
exist, use detergent and hot water. Keep and wash PPE separately from other laundry. 
Engineering Control Statements 
When handlers use closed systems or enclosed cabs in a manner that meets the requirements listed in 
the Worker Protection Standard (WPS) for agricultural pesticides [40 CFR 170.240(d)(4-6)], the handler 
PPE requirements may be reduced or modified as specified in the WPS. 
User Safety Recommendations 
USERS SHOULD: 
x Wash hands before eating, drinking, chewing gum, using tobacco or using the toilet. 
x Remove PPE immediately after handling this product. 
x Wash the outside of gloves before removing. 
x As soon as possible, wash thoroughly and change into clean clothing. 
x Remove clothing/PPE immediately if pesticide gets inside. 
x Then wash thoroughly and put on clean clothing.
First Aid 
x IF IN EYES: Hold eye open and rinse slowly and gently with water for 15-20 minutes. Remove 
contact lenses, if present, after the first 5 minutes, then continue rinsing eye. Call a poison control 
center or doctor for treatment advice. 
x IF ON SKIN OR CLOTHING: Take off contaminated clothing. Rinse skin immediately with plenty of 
water for 15-20 minutes. Call a poison control center or doctor for treatment advice. 
x IF SWALLOWED: Call a poison control center or doctor immediately for treatment advice. Have 
person sip a glass of water if able to swallow. DO NOT induce vomiting unless told to by a poison 
control center or doctor. DO NOT give anything to an unconscious person. 
x IF INHALED: Move person to fresh air. If person is not breathing, call 911 or an ambulance, then 
give artificial respiration, preferably by mouth-to-mouth, if possible. Call a poison control center or 
doctor for further treatment advice. 
Have the product container or label with you when calling a poison control center or doctor, or going for 
treatment. You may also contact 1-800-441-3637992-5994 for emergency medical treatment 
information.

Q2M / Instigate® / MSTR /Notification with edits / 11-21-22 Page 10 
Environmental Hazards 
DO NOT apply directly to water, or to areas where surface water is present or to intertidal areas below the 
mean high water mark. DO NOT contaminate water when disposing of equipment wash water or rinsate. 
Surface Water Label Advisory 
This product may impact surface water quality due to runoff of rain water. This is especially true for poorly 
draining soils and soils with shallow ground water. This product is classified as having high potential for 
reaching surface water via runoff for several months or more after application. A level, well-maintained 
vegetative buffer strip between areas to which this product is applied and surface water features such as 
ponds, streams, and springs will reduce the potential loading of rimsulfuron from runoff water and 
sediment. Runoff of this product will be greatly reduced by avoiding applications when rainfall or irrigation 
is expected to occur within 48 hours. 
Windblown Soil Particles 
This product has the potential to move off-site due to wind erosion. Soils that are subject to wind erosion 
usually have a high silt and/or fine to very fine sand fractions and low organic matter content. Other 
factors which can affects the movement of windblown soil include the intensity and direction of prevailing 
winds, vegetative cover, site slope, rainfall, and drainage patterns. Avoid applying this product if 
prevailing local conditions may be expected to result in off-site movement. 
Non-target Organism Advisory 
This product is toxic to plants and may adversely impact the forage and habitat of non-target organisms, 
including pollinators, in areas adjacent to the treated area. Protect the forage and habitat of non-target 
organisms by minimizing spray drift. For further guidance and instructions on how to minimize spray drift, 
refer to the Spray Drift Management section of this label. 
Directions for Use 
It is a violation of Federal law to use this product in a manner inconsistent with its labeli
ng. 
DO NOT apply this product in a way that will contact workers or other persons, either directly or through 
drift. Only protected handlers may be in the area during application. For any requirements specific to your 
State or Tribe, consult the agency in your State responsible for pesticide regulation. 
DuPont™ INSTIGATE
® herbicide, referred to below as DuPont™ Instigate ,or Instigate herbicide or 
Instigate, must be used only in accordance with instructions on this label, Supplemental Labels, Special 
Local Need Registrations, FIFRA Section 18 exemptions, FIFRA 2ee or as otherwise permitted by FIFRA. 
Always read the entire label, including the Limitation of Warranty and Liability. 
Agricultural Use Requirements 
Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR 
part 170. This Standard contains requirements for the protection of agricultural workers on farms, 
forests, nurseries, and greenhouses, and handlers of agricultural pesticides. It contains requirements 
for training, decontamination, notification, and emergency assistance. It also contains specific 
instructions and exceptions pertaining to the statements on this label about personal protective 
equipment (PPE) and restricted-entry interval. The requirements in this box only apply to uses of this 
product that are covered by the Worker Protection Standard. 
DO NOT enter or allow worker entry into treated areas during the restricted entry interval (REI) of 12 
hours.

Q2M / Instigate® / MSTR /Notification with edits / 11-21-22 Page 11 
PPE required for early entry to the treated areas that is permitted under the Worker Protection 
Standard and that involves contact with anything that has been treated including plants, soil or water, 
is: 
x Coveralls. 
x Chemical-resistant gloves made of any waterproof material including nitrile rubber, natural rubber, 
neoprene rubber, or butyl rubber. 
x Shoes plus socks.
Storage And Disposal 
DO NOT contaminate water, food or feed by storage and disposal. 
Pesticide Storage: Store product in original container only. Store in a cool, dry place. 
Product Disposal: Waste resulting from the use of this product must be disposed of on site or at an 
approved waste disposal facility. 
Container Disposal: Refer to the Net Contents section of this product’s labeling for the 
applicable “Refillable Container” or “Nonrefillable Container” designation. 
Nonrefillable Plastic and Metal Containers (Capacity Equal to or Less Than 50 Pounds): 
Nonrefillable container. DO NOT reuse or refill this container. Triple rinse container (or equivalent) 
promptly after emptying. Triple rinse as follows: Empty the remaining contents into application 
equipment or a mix tank. Fill the container 1/4 full with water and recap. Shake for 10 seconds. Pour 
rinsate into application equipment or a mix tank or store rinsate for later use or disposal. Drain for 10 
seconds after the flow begins to drip. Repeat this procedure two more times. Then, for Plastic 
Containers, offer for recycling if available or puncture and dispose of in a sanitary landfill, or by 
incineration. DO NOT burn, unless allowed by state and local ordinances. For Metal Containers, offer 
for recycling if available or reconditioning if appropriate, or puncture and dispose of in a sanitary landfill, 
or by other procedures approved by state and local authorities. 
Nonrefillable Plastic and Metal Containers (Capacity Greater Than 50 Pounds): Nonrefillable 
container. DO NOT reuse or refill this container. Triple rinse container (or equivalent) promptly after 
emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix 
tank. Fill the container 1/4 full with water. Replace and tighten closures. Tip container on its side and 
roll it back and forth, ensuring at least one complete revolution, for 30 seconds. Stand the container on 
its end and tip it back and forth several times. Turn the container over onto its other end and tip it back 
and forth several times. Empty the rinsate into application equipment or a mix tank or store rinsate for 
later use or disposal. Repeat this procedure two more times. Then, for Plastic Containers, offer for 
recycling if available or puncture and dispose of in a sanitary landfill, or by incineration. DO NOT burn, 
unless allowed by state and local ordinances. For Metal Containers, offer for recycling if available or 
reconditioning if appropriate, or puncture and dispose of in a sanitary landfill, or by other procedures 
approved by state and local authorities. 
Nonrefillable Plastic and Metal Containers, e.g., Intermediate Bulk Containers [IBC] (Size or 
Shape Too Large to be Tipped, Rolled or Turned Upside Down): Nonrefillable container. DO NOT 
reuse or refill this container. Clean container promptly after emptying the contents from this container 
into application equipment or mix tank and before final disposal using the following pressure rinsing 
procedure. Insert a lance fitted with a suitable tank cleaning nozzle into the container and ensure that 
the water spray thoroughly covers the top, bottom and all sides inside the container. The nozzle 
manufacturer generally provides instructions for the appropriate spray pressure, spray duration and/or 
spray volume. If the manufacturer’s instructions are not available, pressure rinse the container for at 
least 60 seconds using a minimum pressure of 30 PSI with a minimum rinse volume of 10% of the 
container volume. Drain, pour or pump rinsate into application equipment or rinsate collection system. 
Repeat this pressure rinsing procedure two more times. Then, for Plastic Containers, offer for recycling 
if available or puncture and dispose of in a sanitary landfill, or by incineration. For Metal Containers, 
offer for recycling if available or reconditioning if appropriate, or puncture and dispose of in a sanitary 
landfill, or by other procedures approved by state and local authorities.

Q2M / Instigate® / MSTR /Notification with edits / 11-21-22 Page 12 
Nonrefillable Paper or Plastic Bags, Fiber Sacks including Flexible Intermediate Bulk 
Containers (FIBC) or Fiber Drums With Liners: Nonrefillable container. DO NOT reuse or refill this 
container. Completely empty paper or plastic bag, fiber sack or drum liner by shaking and tapping sides 
and bottom to loosen clinging particles. Empty residue into application or manufacturing equipment. 
Then offer for recycling if available or dispose of empty paper or plastic bag, fiber sack or fiber drum 
and liner in a sanitary landfill, or by incineration. DO NOT burn, unless allowed by state and local 
ordinances. 
Refillable Fiber Drums With Liners: Refillable container (fiber drum only). Refilling Fiber Drum: Refill 
this fiber drum with DuPont Instigate herbicide containing rimsulfuron and mesotrione only. DO NOT 
reuse this fiber drum for any other purpose. Cleaning before refilling is the responsibility of the refiller. 
Completely empty liner by shaking and tapping sides and bottom to loosen clinging particles. Empty 
residue into application or manufacturing equipment. Disposing of Fiber Drum and/or Liner: DO NOT 
reuse this fiber drum for any other purpose other than refilling (see preceding). Cleaning the container 
(liner and/or fiber drum) before final disposal is the responsibility of the person disposing of the 
container. Offer the liner for recycling if available or dispose of liner in a sanitary landfill, or by 
incineration. DO NOT burn, unless allowed by state and local ordinances. If drum is contaminated and 
cannot be reused, dispose of it in the manner required for its liner. To clean the fiber drum before final 
disposal, completely empty the fiber drum by shaking and tapping sides and bottom to loosen clinging 
particles. Empty residue into application or manufacturing equipment. Then offer the fiber drum for 
recycling if available or dispose of in a sanitary landfill, or by incineration. DO NOT burn, unless 
allowed by state and local ordinances. 
All Other Refillable Containers: Refillable container. Refilling Container: Refill this container with 
DuPont Instigate containing rimsulfuron and mesotrione only. DO NOT reuse this container for any 
other purpose. Cleaning before refilling is the responsibility of the refiller. Prior to refilling, inspect 
carefully for damage such as cracks, punctures, abrasions, worn out threads and closure devices. If 
damage is found, DO NOT use the container, contact DuPont Corteva Agriscience at the number 
below for instructions. Check for leaks after refilling and before transporting. If leaks are found, DO 
NOT reuse or transport container, contact DuPont Corteva Agriscience at the number below for 
instructions. Disposing of Container: DO NOT reuse this container for any other purpose other than 
refilling (see preceding). Cleaning the container before final disposal is the responsibility of the person 
disposing of the container. To clean the container before final disposal, use the following pressure 
rinsing procedure. Insert a lance fitted with a suitable tank cleaning nozzle into the container and 
ensure that the water spray thoroughly covers the top, bottom and all sides inside the container. The 
nozzle manufacturer generally provides instructions for the appropriate spray pressure, spray duration 
and/or spray volume. If the manufacturer’s instructions are not available, pressure rinse the container 
for at least 60 seconds using a minimum pressure of 30 PSI with a minimum rinse volume of 10% of 
the container volume. Drain, pour or pump rinsate into application equipment or rinsate collection 
system. Repeat this pressure rinsing procedure two more times. Then, for Plastic Containers, offer for 
recycling if available or puncture and dispose of in a sanitary landfill, or by incineration. DO NOT burn, 
unless allowed by state and local ordinances. For Metal Containers, offer for recycling if available or 
reconditioning if appropriate, or puncture and dispose of in a sanitary landfill, or by other procedures 
approved by state and local authorities. 
Outer Foil Pouches of Water Soluble Packets (WSP): Nonrefillable container. DO NOT reuse or 
refill this container. Offer for recycling if available or, dispose of the empty outer foil pouch in the trash 
as long as WSP is unbroken. If the outer pouch contacts the formulated product in any way, the pouch 
must be triple rinsed with clean water. Add the rinsate to the spray tank and dispose of the outer pouch 
as described previously. 
DO NOT transport if this container is damaged or leaking. If the container is damaged, leaking or 
obsolete, or in the event of a major spill, fire or other emergency, contact DuPont Corteva Agriscience 
at 1-800-441-3637992-5994, day or night.

Q2M / Instigate® / MSTR /Notification with edits / 11-21-22 Page 13 
Product Information 
Instigate herbicide must be used only in accordance with instructions on this label or in supplemental 
DuPont company publications. DuPont Corteva Agriscience will not be responsible for losses or damage 
resulting from use of this product in any manner not specifically specified by DuPontCorteva Agriscience. 
DuPont™ In
stigate herbicide is a water dispersible blend containing 45.8% active ingredients by weight. 
Instigate is a 
selective herbicide for burndown and residual control of certain annual grass and broadleaf 
weeds. Instigate can be tank mixed with a variety of corn herbicides to improve burndown and residual 
control. 
Instigate is a blend of rimsulfuron and mesotrione, two active ingredients that have different mode-of-
action on susceptible weeds. 
When surface applied, rainfall or sprinkler irrigation is needed to move Instigate into the soil root zone. 
Instigate is absorbed through the roots, rapidly inhibiting plant growth. Susceptible weeds will generally 
not emerge from preemergence application. In some cases susceptible weeds may germinate and 
emerge a few days after application, but growth then ceases and leaves become chlorotic three to five 
days after emergence. Death of leaf tissue and growing point will follow in some species, while others will 
remain green but stunted and noncompetitive. Dry conditions following application may reduce the 
preemergence activity of Instigate. If an activating rain (0.5 inches) is not received within 5-7 days after 
preemergence application, where appropriate, rotary hoeing is suggested to activate the herbicide. 
When applied to emerged vegetation, susceptible weeds take up the herbicide through the treated foliage 
and cease growth soon after application. Complete death of susceptible weeds may take up to 2 weeks. 
On all field corn hybrids, Instigate can be used in a planned sequential application herbicide program 
such as Instigate followed by an in-crop application of DuPont™ ACCENT®Accent Q, DuPont™ 
REALM®Realm Q, DuPont™ RESOLVE®Resolve Q, DuPont™ REVULIN® QRevulin or DuPont™ 
STEADFAST®Steadfast Q with appropriate tank mix partners not exceeding 1.0 ounce active ingredient 
rimsulfuron or 3.85 ounces active ingredient of mesotrione during the crop year. 
For glyphosate-tolerant field corn hybrids, Instigate can be followed by an in-crop application of a 
glyphosate product with appropriate tank mix partners and adjuvant products. 
Refer to the label of the respective sequential partner for specific use directions. 
Restrictions 
x DO NO
T make more than 1 application of Instigate per year. 
x DO NOT apply to corn grown for seed, popcorn, ornamental (Indian) corn, or sweet corn. 
x DO NOT apply another solo HPPD inhibitor postemergence herbicide such as mesotrione, 
topramezone or tembotrione to ground that has been treated with Instigate in the same season. 
x DO NOT apply preemergence to coarse-textured soils (sand, loamy sand or sandy loam) with 
less than 1% organic matter. 
x DO NOT apply more than 3.85 ounces active ingredient of mesotrione in a year. This includes 
combinations of preemergence applications of Instigate, as well as mesotrione from application(s) 
of pre-mix products including REALM®Realm Q or REVULIN®Revulin Q. DO NOT make the 
second application of a mesotrione containing product within 14 days of the first application. 
x DO NOT apply more than a total of 1.0 ounce active ingredient rimsulfuron during the crop year. 
This includes combinations of preemergence applications of Instigate, as well as rimsulfuron from 
application(s) of products including DuPont™ BASIS®Basis Blend, DuPont™ 
LEADOFF™Leadoff, DuPont™ PREQUEL®Prequel, DuPont™ RESOLVE®Resolve Q, 
REALM®Realm Q or DuPont™ STEADFAST®Steadfast Q.

Q2M / Instigate® / MSTR /Notification with edits / 11-21-22 Page 14 
x DO NOT tank mix Instigate with bentazon products or severe crop injury may occur. 
x DO NOT tank mix Instigate with foliar-applied organophosphate or carbamate insecticides 
including chlorpyrifos, malathion, parathion, etc, as severe crop injury may occur. To avoid crop 
injury or antagonism, apply these products at least seven days before or 3 days after the 
application of Instigate. 
x DO NOT apply the organophosphate insecticide, terbufos within 45 days of a preemergence or 
preplant application of Instigate since crop injury may result. 
x DO NOT apply Instigate within 45 days of crop emergence where the organophosphate 
insecticide, terbufos was applied as a treatment since crop injury may occur. 
x DO NOT irrigate Instigate herbicide into coarse soils at planting time when soils are saturated. 
x DO NOT apply this product through any type of irrigation system. 
x DO NOT use aerial application to apply Instigate unless specified otherwise under the specific 
crop section on the label. 
x DO NOT apply with suspension fertilizers as the carrier, unless specifically addressed under one 
of the tank mix sections of this label or other product labels containing mesotrione, or injury may 
occur. 
x DO NOT graze, feed forage, grain or fodder (stover) from treated areas to livestock within 45 
days of Instigate application. 
Injury or loss of desirable trees or vegetation may result from failure to observe the following: 
- DO NOT apply Instigate or drain or flush application equipment on or near desirable trees or
other plants, or on areas where their roots may extend, or in locations where the chemical may be
washed or moved into contact with their roots.
- DO NOT use on lawns, walks, driveways, tennis courts, or similar areas.
- DO NOT contaminate any body of water.
Use Restriction Summary Table for INSTIGATE®Instigate: 
CROPS
Maximum 
Oz of Product/ 
Acre/ Single 
Application 
Maximum 
Lb AI/ 
Acre/Single 
Application 
Maximum 
Number of 
Applications 
per 
Year 
Maximum 
Oz of 
Product 
/Acre/Year 
Maximum 
Lb AI/A 
per 
Year 
Retreat 
Interval 
(Days) 
Last 
Treatment 
Preharvest 
Interval 
field corn 
grown for 
grain or 
silage 
7.0 oz 
0.0182 lb ai 
rimsulfuron + 
0.182 lb ai 
mesotrione 
1 7.0 oz 
0.0182 lb ai 
rimsulfuron + 
0.182 lb ai 
mesotrione 
N/A 
Do not 
harvest 
forage, 
grain, or 
stover 
within 45 
days after 
application 
Precautions 
Allow at least
 4 weeks between preemergence application of DuPont Instigate and postemergence 
applications of unsafened rimsulfuron-containing herbicides. 
Instigate herbicide may interact with certain insecticides previously applied to the crop. Crop response 
varies with field corn type, insecticide used, insecticide application method, and soil type. 
Preplant/Preemergence applications of Instigate to corn where an application of terbufos, chlorpyrifos, or 
phorate is planned may cause unacceptable crop injury, especially on soils of less than 4% organic 
matter.

Q2M / Instigate® / MSTR /Notification with edits / 11-21-22 Page 15 
Instigate may be applied to corn previously treated with chlorethoxyfos + bifenthrin, tebupirimphose + 
cyfluthrin, or tefluthrin insecticides, or other non-organophosphate soil insecticides regardless of soil type. 
Instigate may be applied with pyrethroid type insecticides including esfenvalerate or lambda-cyhalothrin 
or with diamide type insecticides including PREVATHONPrevathon®. 
Whe
n weeds are stressed due to drought, heat, lack of fertility, flooding, or prolonged cool temperatures, 
control can be reduced or delayed since the weeds are not actively growing. 
Weed escapes or regrowth may occur when application is made under prolonged stress conditions. 
Optimum weed control will be obtained if an application of Instigate is made following label direction when 
weeds are actively growing. 
Crop injury may occur following an application of Instigate if there is a prolonged period of cold weather 
and/or in conjunction with wet soils. 
Prevent drift or spray onto desirable plants. 
Thoroughly clean application equipment immediately after use. 
Weed Resistance Management 
Instigate, whi
ch contains the active ingredients rimsulfuron and mesotrione, is both a Group 2 and a 
Group 27 herbicide based on the mode of action classification system of the Weed Science Society of 
America. 
Proactively implementing diversified weed control strategies to minimize selection for weed populations 
resistant to one or more herbicides is a best practice. A diversified weed management program may 
include the use of multiple herbicides with different sites of action and overlapping weed spectrum with or 
without tillage operations and/or other cultural practices. Research has demonstrated that using the 
labeled rate and directions for use is important to delay the selection for resistance. 
The continued effectiveness of this product depends on the successful implementation of a weed 
resistance management program. 
To aid in the prevention of developing weeds resistant to this product, users should: 
x Scout fields before application to ensure herbicides and rates will be appropriate for the weed 
species and weed sizes present. 
x Start with a clean field, using either a burndown herbicide application or tillage. 
x Control weeds early when they are relatively small (less than 4 inches). 
x Apply full rates of Instigate herbicide for the most difficult to control weed in the field at the 
specified time (correct weed size) to minimize weed escapes. 
x Scout fields after application to detect weed esc apes or shifts in control of weed species. 
x Control weed escapes before they reproduce by seed or proliferate vegetatively. 
x Report any incidence of non-performance of this product against a particular weed to your 
company representative, local retailer, or county extension agent. 
x Contact your company representative, crop advisor, or extension agent to find out if suspected 
resistant weeds to this MOA have been found in your region. If resistant biotypes of target weeds 
have been reported, use the application rates of this product specified for your local conditions. 
Tank mix products so that there are multiple effective sites of actions for each target weed. 
x If resistance is suspected, treat weed escapes with an herbicide having a site of action other than 
Group 2 or 27 and/or use nonchemical methods to remove escapes, as practical, with the goal of 
preventing further seed production. 
x Suspected herbicide-resistant weeds may be identified by these indicators:

Q2M / Instigate® / MSTR /Notification with edits / 11-21-22 Page 16 
x Failure to control a weed species normally controlled by the herbicide at the dose applied, 
especially if control is achieved on adjacent weeds; 
x A spreading patch of non-controlled plants of a particular weed species; and 
x Surviving plants mixed with controlled individuals of the same species. 
Additionally, users should follow as many of the following herbicide resistance management practices as 
is practical: 
x Use a broad spectrum soil-applied herbicide with other sites of action as a foundation in a weed 
control program. 
x Utilize sequential applications of herbicides with alternative sites of action. 
x Rotate the use of this product with non-Group 2 or 27 herbicides. 
x Avoid making more than two applications of DuPont Instigate and any other Group 2 or 27 
herbicides within a single growing season unless mixed with an herbicide with a different site of 
action with an overlapping spectrum for the difficult-to-control weeds. 
x Incorporate non-chemical weed control practices, such as mechanical cultivation, crop rotation, 
cover crops and weed-free crop seeds, as part of an integrated weed control program. 
x Use good agronomic principles that enhance crop development and crop competitiveness. 
x Thoroughly clean plant residues from equipment before leaving fields suspected to contain 
resistant weeds. 
x Manage weeds in and around fields, during and after harvest to reduce weed seed production. 
Integrated Pest Management 
This p
roduct may be used as part of an Integrated Pest Management (IPM) program that can include 
biological, cultural, and genetic practices aimed at preventing economic pest damage. IPM principles and 
practices include field scouting or other detection methods, correct target pest identification, population 
monitoring, and treating when target pest populations reach locally determined action thresholds. Consult 
your state cooperative extension service, professional consultants or other qualified authorities to 
determine appropriate action treatment threshold levels for treating specific pest/crop systems in your 
area. 
APPLICATION INFORMATION – ALL USES 
Rate of 
INSTIGATE®Instigate 
Pounds of Active 
Ingredient 
Rimsulfuron 
Pounds of Active 
Ingredient 
Mesotrione 
5.25 oz 0.0137 0.137 
6.0 oz 0.0156 0.156 
7.0 oz 0.0182 0.182 
Application Information - Field Corn Grown for Grain or Silage 
Instigate he
rbicide may be used in either conventional, conservation tillage, or no-till crop management 
systems and may be applied either preplant, preplant incorporated (less than 2” deep), preemergence, or 
early postemergence to field corn. Instigate herbicide can be applied to corn that exhibits up through 2 
leaf collars. 
Application Timings 
Preplant Surface-Applied or Preplant Incorporated: Instigate herbicide may be up to 14 days applied 
prior to planting. For preplant incorporated treatments apply to the soil and uniformly incorporate in the 
top two inches of soil before planting using a finishing disc harrow, field cultivator or similar implement 
capable of providing uniform two inch incorporation. DO NOT incorporate Instigate deeper than 2” or 
weed control may be reduced.

Q2M / Instigate® / MSTR /Notification with edits / 11-21-22 Page 17 
Preplant/Preemergence Burndown: Instigate may be applied when weeds are present at the time of 
treatment. The addition of crop oil concentrate or methylated seed oil is recommended for burndown of 
labeled weeds 3 inches or less in height. When weeds are greater than 3” in height or weeds not 
controlled by Instigate herbicide are present, the addition of a burndown herbicide (e.g. paraquat, 
glyphosate, dicamba and/or 2,4-D) is recommended. If giant ragweed, common cocklebur, henbit, 
Pennsylvania smartweed or purple deadnettle are present at the time of application, the addition of 
atrazine or atrazine-containing herbicides will improve control. Observe directions for use and precautions 
and restrictions on the label of the burndown label herbicide. When mixing with liquid nitrogen fertilizer or 
glyphosate, substitute a non-ionic surfactant for crop oil concentrate. When tank mixing with EC 
formulation herbicides, such as DuPont™ CINCH®Cinch or Surpass
® NXT, refer to TANK MIXING 
section for additional adjuvant information. 
Preemergence: Apply Instigate herbicide during planting (behind the planter after furrow closure) or after 
planting, but before crop emergence. Failure to thoroughly close and firm the seed furrow may allow 
herbicide to directly contact the seed which can cause injury. 
Early Postemergence Treatment: In the event planned preemergence applications are delayed and 
corn is emerging, application may be made to emerged corn up through 2 collars. Use only clean water 
as the carrier when applying Instigate after corn emergence. 
For control of labeled emerged weeds, applications of Instigate must include a crop oil concentrate or a 
nonionic surfactant. In addition, nitrogen based adjuvant (UAN or AMS) must be used unless specifically 
prohibited by tank mix partner labeling. Crop oil concentrate plus nitrogen based adjuvant is the preferred 
adjuvant system for Instigate for control of labeled emerged weeds. When applied in tank mix 
combination with a glyphosate that contains a built-in adjuvant, ensure the total adjuvant load is 
equivalent to the recommendations on this label. Select adjuvants authorized for use with both products. 
Best results are obtained when applications are made to actively growing plants. Instigate is rainfast 1 
hour after application. 
DO NOT use with spray additives that alter the pH of the spray solution below 5.0 or above 9.0 as rapid 
product degradation can occur. Spray solutions of pH 6.0 – 8.0 allow for optimum stability of Instigate. 
Application Rate 
The typical DuPont Instigate use rate for most soils and application situations is 6 oz product per acre. 
Instigate may be applied within a rate range of 5.25 - 7.0 oz product per acre before corn emergence. 
Use higher rates on fine soils (silty clay loam, clay loam, sandy clay, silty clay or clay) or on soils with 
greater than 3% organic matter. DO NOT apply to coarse soils (sand, loamy sandy or sandy loam) with 
less than 1% organic matter. See cumulative rimsulfuron and mesotrione rate limitations noted under 
"Restrictions.” 
Instigate may be applied at 5.25 to 6.0 oz product per acre for early postemergence treatment on corn 
exhibiting up through 2 leaf collars. 
Spray Adjuvants 
When an adjuvant is to be used with this product, the use of an adjuvant that meets the standards of the 
Chemical Producers and Distributors Association (CPDA) adjuvant certification program is recommended. 
For preplant or preemergence burndown applications, for control of emerged labeled weeds, application 
of Instigate must include a crop oil concentrate, modified seed oil or a nonionic surfactant. In addition, 
nitrogen based adjuvant (UAN or AMS) must be used unless specifically prohibited by the tankmix partner 
labeling. Crop oil concentrate/modified seed oil plus nitrogen based adjuvant is the preferred adjuvant 
systems. When applied in tank mix combination with a glyphosate or glufosinate herbicide that contains a 
built-in adjuvant system, ensure the total adjuvant load is equivalent to the recommendations on this

Q2M / Instigate® / MSTR /Notification with edits / 11-21-22 Page 18 
label. Select adjuvants authorized for use with both products. 
Instigate applied postemergence to the corn must include a crop oil concentrate or a nonionic surfactant. 
The use of methylated seed oil (MSO) adjuvants or MSO blend adjuvants may cause severe crop 
injury to occur. MSO adjuvants are not recommended. In addition, an ammonium nitrogen fertilizer 
must be used unless specifically prohibited by tank mix partner labeling. See TANK MIXING section for 
additional adjuvant information if tank mixing Instigate with EC formulation herbicides. 
Weeds Controlled 
Instigate applied as directed in this label will control or suppress the weeds listed in Tables 1 and 2. 
Additional weeds may be controlled with tank mixes. See the TANK MIXTURES section for recommended 
tank mix combinations. 
Table 1: Contact Weed Control with DuPont Instigate* Herbicide 
Common Name Instigate + 2,4-D Instigate + glyphosate Instigate + Atrazine 
Alfalfa, volunteer C C C
Amaranth, Palmer C C C
Amaranth, Powell C C C
Amaranth, spiny C C C
Barley, volunteer C C C
Barnyardgrass C C C
Bluegrass, annual C C C
Buckwheat, wild C C C
Buffalobur C C C
Burcumber C C C
Butterweed C C C
Carpetweed C C C
Carrot, wild C C C
Chamomile, false C C C
Chickweed, common C C C
Cocklebur C C C
Crabgrass, large (1/2") C C C 
Cupgrass, woolly (1") C C C 
Dandelion (6" dia) C C C 
Deadnettle C C C
Dock, curly PC C C 
Filaree, redstem S C 
Foxtail, bristly C C C
Foxtail, giant C C C
Foxtail, green C C C
Foxtail, yellow C C C
Galinsoga C C C
Hemp C C C
Henbit C C C
Horsenettle C C C
Jimsonweed C C C
Johnsongrass, seedling PC C C 
Knotweed, prostrate PC 
Kochia NC C C
Kochia (ALS-sensitive) C C C
Lambsquarters, common C C C
Mallow, Venice C 
Marestail C C C
Millet, Wild Proso PC C C 
Morningglory, ivyleaf C C C

Q2M / Instigate® / MSTR /Notification with edits / 11-21-22 Page 19 
Mustard, birdsrape C C C
Mustard, black C C C
Mustard, wild C C C
Nightshade, eastern black C C C 
Nightshade, hairy C C C
Nutsedge, yellow C C C
Oat, wild C C C
Panicum, fall C C C
Pigweed, prostrate C C C
Pigweed, redroot C C C
Pigweed, smooth C C C
Pigweed, tumble C C C
Pokeweed, common C C C
Purslane, common PC PC PC
Pusley, FL PC C C 
Quackgrass C
Radish, wild C C C
Ragweed, common C C C
Ragweed, giant C C C
Ryegrass, Italian C C C
Sandbur, field PC C 
Sesbania, hemp PC C C 
Shattercane C C C
Shepherdspurse C C C
Sida, prickly C C C
Signalgrass, broadleaf C C C
Smartweed, annual C C C
Stinkgrass PC C C
Sunflower C C C
Thistle, Canada C C C
Thistle, Russian, seedling C C C 
Velvetleaf C C C
Waterhemp C C C
Wheat, volunteer C C C
* Apply to weeds less than 5 inches tall. For control of emerged weeds the Instigate application must include the appropriate spray
adjuvant. Refer t
o the SPRAY ADJUVANTS and TANK MIXTURES sections of the label.
Table 2: 
Residual Weed Control with Preemergence Applications of DuPont Instigate Herbicide 
Common Name Instigate Instigate + Atrazine 
Instigate + DuPont™ 
Cinch® or 
Surpass NXT 
Amaranth, Palmer PC C C
Amaranth, Powell PC C C 
Amaranth, spiny C C C
Barnyardgrass C C C
Bluegrass, annual PC C C 
Buffalobur C C C
Burcucumber PC PC PC
Carpetweed PC C C
Chamomile, false C C C
Chickweed, common C C C
Cocklebur C C C
Crabgrass, large PC C C 
Crowfootgrass C
Cupgrass, praire C 
Cupgrass, southwestern C

Q2M / Instigate® / MSTR /Notification with edits / 11-21-22 Page 20 
Filaree, redstem C C C
Fotail, bristly C C C
Foxtail, giant C C C
Foxtail, green C C C
Foxtail, yellow C C C
Galinsoga C C C
Goosegrass C
Henbit C C C
Jimsonweed C C C
Kochia PC C C
Kochia (ALS-sensitive) C C C
Lambsquarters, common C C C
Marestail C C C
Morningglory, ivyleaf PC C C 
Morningglory, pitted PC C C 
Mustard, birdsrape C C C
Mustard, black C C C
Mustard, wild C C C
Nightshade, eastern black C C C 
Nightshade, hairy C C C
Oat, wild PC C C 
Panicum, browntop C 
Panicum, fall C C C
Pigweed, prostrate PC C C 
Pigweed, redroot C C C
Pigweed, smooth C C C
Pokeweed, common C C C
Purslane, common C C C
Pusley, FL C 
Ragweed, common C C C
Ragweed, giant PC C C 
Ryegrass, Italian C C C
Sicklepod PC PC
Signalgrass, broadleaf PC C C 
Smartweed, annual C C C
Sunflower C C C
Thistle, Russian PC C C 
Velvetleaf C C C
Waterhemp PC C C
Wheat, volunteer C C C
Witchgrass C
C = CONTROL, PC = PARTIAL CONTROL 
Tank Mixtur
es 
DuPont Instigate may be tank mixed with preemergence corn herbicides including atrazine, glyphosate, 
dicamba, 2,4-D, DuPont™ CINCH®Cinch and Surpass NXT to provide added residual activity or 
burndown activity on emerged weeds. Consult tank mix partner labeling for rate and soil-type restrictions. 
Ensure the tank mix product is labeled for the same timing, method of application, adjuvants, and use 
restrictions as Instigate and other products used in the tank mixture. 
Ensure the tank mixture is not specifically prohibited on the label of the tank mix product. 
For postemergence applications to corn if mixing with an EC formulation including CINCH®Cinch or 
Surpass® NXT the user should leave the crop oil concentrate (COC) out of the adjuvant mix. These 
herbicides can act like an adjuvant in certain combinations and thus increase the risk of crop injury.

Q2M / Instigate® / MSTR /Notification with edits / 11-21-22 Page 21 
Instigate may be tank mixed with CINCH®Cinch ATZ, CINCH®Cinch ATZ LITE, FulTime® NXT, 
Keystone® NXT, or Keystone® LA NXT postemergence to the corn, but special attention must be paid to 
adjuvant selection and/or application method. If any of these tank mixtures are used the user should 
leave the urea ammonium nitrate (UAN) out of the mix. 
There is still a risk of temporary crop injury in the form of leaf burn with these mixtures. To further reduce 
the risk of crop injury, the user may also leave out the crop oil concentrate (COC) or replace it with a 
nonionic surfactant (NIS). In either case, the control of emerged weeds may be reduced somewhat due to 
less than optimum adjuvant effect or weed coverage and there is still a risk of temporary crop injury in the 
form of leaf burn with these mixtures. 
It is the pesticide user’s responsibility to ensure that all products are registered for the intended use. Read 
and follow the applicable restrictions and limitations and directions for use on all product labels involved in 
tank mixing. Users must follow the most restrictive directions for use and precautionary statements of 
each product in the tank mixture. 
Mixing instructions 
Fertilizer carrier instructions 
Instigate may be mixed with water or pre-slurried in water and added to liquid fertilizer (excluding 
suspension fertilizers) for preemergence application. When using liquid fertilizer as the carrier, always 
pre-slurry Instigate in water before adding fertilizer solutions. Add the Instigate slurry to the final liquid 
fertilizer mixture – DO NOT add Instigate during the fertilizer mixing process. Always use good agitation 
while adding the Instigate slurry to the liquid fertilizer. Maintain good agitation until sprayed. 
When using liquid fertilizer as the carrier, conduct a compatibility test with all the components prior to 
mixing. 
DO NOT use with spray additives or liquid fertilizer carriers that alter the pH of the spray solution below 
pH 5.0 or above pH 9.0 as rapid degradation may occur. Spray solutions of pH 6.0-8.0 allow for optimum 
stability of Instigate. 
Water Carrier Instructions 
1.
Fill the tank 1/4 to 1/3 full of water.
2.
While agitating, add the required amount of Instigate.
3.
Continue agitation until the Instigate is fully dispersed, at least 5 minutes.
4.
Once the Instigate is fully dispersed, maintain agitation and continue filling tank with water.
Instigate sho
uld be thoroughly mixed with water before adding any other material.
5.
As the tank is filling, add tank mix partners (if desired).
6.
If the mixture is not continuously agitated, settling will occur. If settling occurs, thoroughly re-
agitate before using.
7.
At the end of the day, or for extended periods of time between Instigate applications, it is
recomme
nded to flush boom hoses and lines of spray solution and recharge with clean water.
This will ai
d in proper sprayer cleanout when concluding Instigate applications before moving on
to spra
y other products/crops.
8.
Apply Instigate spray mixture within 48 hours of mixing to avoid product degradation.
Tank Mix Compatibility 
Testing 
Perform a jar test prior to tank mixing to ensure compatibility of Instigate and other pesticides. Use a clear 
glass quart jar with lid and mix the tank mix ingredients in their relative proportions. Invert the jar 
containing the mixture several times and observe the mixture for approximately 1/2 hour. If the mixture 
balls-up, forms flakes, sludges, gels, oily films or layers or other precipitates, it is not compatible, and the 
tank mix combination must not be used.

Q2M / Instigate® / MSTR /Notification with edits / 11-21-22 Page 22 
Application and Spray Volumes 
Ground Application (Also refer to Spray Drift Management section) 
Avoid spray overlaps as excessive rates may result in adverse crop response. 
Spray nozzle should be uniformly spaced the same size and type, and should provide accurate and 
uniform application. Use spray nozzles that provide medium to coarse droplet size to provide good 
coverage and avoid drift. Apply in a spray volume of 10-80 gals/A using water or liquid fertilizer (excluding 
suspension fertilizers) as the carrier. Use a pump that can maintain a pressure of at least 35-40 psi at the 
nozzles and provide proper agitation within the tank to keep the product dispersed. Lower pressure may 
be used with extended range or drift reduction nozzles. 
Always ensue that agitation is maintained until spraying is completed, even if stopped for brief periods of 
time. If the agitation is stopped for more than 5 minutes, re-suspend the spray solution by running on full 
agitation prior to spraying. 
To minimize spray drift to non-target areas, apply this product using nozzles which deliver a coarse or 
larger spray droplet as defined by ASAE standard S-572 and as shown in nozzle manufacturer’s 
catalogues. Keep the spray boom at the lowest possible spray height above the target surface. Refer to 
nozzle manufacturer’s recommendations for proper nozzle, pressure setting and sprayer speed for 
optimum product performance and minimal spray drift. Use sprayers that provide accurate and uniform 
application. 
Maintain adequate agitation at all times, including momentary stops. 
Aerial Application (Also refer to Spray Drift Management section) 
DuPont Instigate may be applied aerially for preemergence or postemergence weed control only in the 
following states: Alabama, Arkansas, Colorado, Florida, Georgia, Illinois, Indiana, Iowa, Kansas, 
Kentucky, Louisiana, Minnesota, Mississippi, Missouri, Nebraska, North Dakota, Ohio, Oklahoma, South 
Dakota, Tennessee, and Texas. 
For aerial application use only nozzles producing coarse-ultra coarse droplets. DO NOT use nozzles 
producing fine-medium size droplets. 
Applications must be made in a minimum of 2 gallons of water per acre. 
Rotational Crop Guidelines 
Rotational crops vary in their crop response to low concentrations of Instigate remaining in the soil. The 
amount of Instigate that may be present in the soil depends on soil moisture, soil temperature, application 
rate, elapsed time since application and other environmental factors. When Instigate is used in 
combination with other products, always follow the most restrictive rotational crop requirements. 
The following rotational intervals must be observed when Instigate is applied at 5.25 - 7.0 oz per acre: 
Rotation Crop Interval 
(months) 
Corn, field Anytime 
Cereals, Winter 4 
Cereals, Spring 9
Alfalfa†* 10
Canola† 10
Corn, pop, sweet, or seed 10

Q2M / Instigate® / MSTR /Notification with edits / 11-21-22 Page 23 
Cotton† 10
Flax 10
Peanuts 10
Peas1,2 10 
Potatoes 10
Rice 10
Snap beans1,2 10 
Sorghum† 10
Soybeans 10
Sunflower 10
Sweet potatoes/yams** 10
Tobacco 10
Crops Not Listed 18 
† 18 months in the Red River Valley region of ND and MN. In all other areas, the rotation intervals should be extended to 18 months 
if drought conditions prevail after application and before the rotational crop is planted, unless sprinkler irrigation has been applied 
and totals greater than 15” during the growing season. 
* On sprinkler irrigated fields in Idaho, Utah, and Northern Nevada it is best to use deep fall tillage such as plowing prior to planting
alfalfa. Product d
egradation may be less on furrow irrigated soils and may result in some crop injury.
**On soils with pH 6.5 or less. 
1.Plant these rotational crops only if the following criteria below have been met. If all criteria are not met, plant peas and snap beans
a minimum of 18 months following Instigate application.
- A minimum of 2
0" of rainfall plus irrigation has been received between application and planting of the rotational crop.
- Soil pH is 6.0 or greater.
- Application of Instigate applied no later than Ju
ne 30 the year preceding rotational crop planting.
- No othe
r HPPD herbicides were applied the year prior to planting peas and snap beans.
2.DO NOT plant peas or snap beans on sand, sandy loam or loamy sands in Minnesota or Wisconsin.
Planting unspecified rotational crops, or those rotational crops that are specified at shorter than listed intervals may result in injury to 
the rotational crop. 
Cover Crops 
Use of cover crops as a means of soil improvement, erosion control, weed and/or insect suppression, 
etc., following harvest of corn in the fall is increasing. Planting of cover crops in fields treated with DuPont 
Instigate is allowed as long as these cover crops are not grazed by livestock nor harvested for food. 
Cover crops are to be tilled under or chemically controlled with burndown herbicides in the spring. Many 
cover crops can be planted within 90-120 days after application of Instigate. However, all potential cover 
crops have not been evaluated for tolerance to Instigate and significant injury may occur. Prior to seeding 
a cover crop complete a successful field/ home bioassay to provide an indication of the level of tolerance 
to the prior Instigate application. Refer to the “Field/Small Scale Bioassay” section. If used in tank 
mixtures with other herbicides, always follow the most restrictive label. 
Field/Small Scale Bioassay 
A field/ small scale bioassay must be completed before rotating to a cover crop other than those specified 
in the “Rotational Crop Guidelines” section of this label. To conduct an effective field bioassay, grow strips 
of the crop(s) you intend to grow the following season in a field previously treated with Instigate. The test 
strip should be placed in a controlled area and should include low areas and knolls, and include variations 
in soil such as type and pH. Crop response to the bioassay will determine if the crop(s) grown in the test 
strips can be grown safely in the areas previously treated with Instigate. 
For an effective small scale bioassay, collect uniform samples of all soil types from the Instigate treated 
field (see example above for types of soil in the sample) and place the soil into a sturdy container. Plant 
the desired cover crop into the soil, apply water and place the container in a warm, sunny area to allow 
germination and growth of the crop. Monitor growth of the cover crop over a three to four week period. If 
the cover crop emerges and grows normally, the risk to establish and grow the cover crop in the field 
treated with Instigate should be tolerable.

Q2M / Instigate® / MSTR /Notification with edits / 11-21-22 Page 24 
Sprayer Preparation/Cleanup 
It is important that spray equipment is clean and free of previous pesticide deposits before using Instigate 
and then properly cleaned out following application. Clean all application equipment before applying 
Instigate. Follow the cleanup procedures specified on the label of the product previously sprayed. If no 
cleanup procedure is provided, use the procedure that follows. Immediately following applications of 
Instigate, thoroughly clean all mixing and spray equipment to avoid subsequent crop injury. 
When cleaning spray equipment before applying Instigate, read and follow label directions for proper 
rinsate disposal of the product previously sprayed. 
When spraying or mixing equipment will be used over an extended period to apply multiple loads of 
Instigate, partially fill the tank with fresh water at the end of each day of spraying, flush the boom and 
hoses, and allow to sit overnight. 
Cleanup Procedure 
1. Drain the tank and thoroughly hose down the interior surfaces. Flush the tank, hoses, and boom
with clean water for a minimum of 5 min.
2. Partially fill the tank with clean water and add one gal of household ammonia (containing 3%
active) for every 100 gal of water. Finish filling the tank with water, then flush the cleaning solution
through the hoses, boom, and nozzles. Add more water to completely fill the tank and allow to
agitate/recirculate for at least 15 min. Again, flush the hoses, boom, and nozzles with the cleaning
solution, then drain the tank.
3. Repeat Step 2.
4. Remove the nozzles, screens and the end caps of sprayer booms and clean separately in a
bucket containing the cleaning agent and water.
5. Thoroughly rinse the tank with clean water for a minimum of 5 min, flushing the water through the
hoses and boom.
Mandatory Spray Drift Management 
Aerial Applications: 
x Do not release spray at a height greater than 10 ft above the vegetative canopy, unless a 
greater application height is necessary for pilot safety. 
x For applications prior to the emergence of crops and target weeds, applicators are required to use 
a Coarse or coarser droplet size (ASABE S572.1) 
x For all other applications, applicators are required to use a Medium or coarser droplet size (ASABE 
S572.1). 
x The boom length must not exceed 65% of the wingspan for airplanes or 75% of the rotor blade 
diameter for helicopters. 
x Applicators must use 1/2 swath displacement upwind at the downwind edge of the field. 
x Nozzles must be oriented so the spray is directed toward the back of the aircraft. 
x DO NOT apply when wind speeds exceed 10 miles per hour at the application site. 
x DO NOT apply during temperature inversions. 
Ground Boom Applications: 
x Apply with the nozzle height recommended by the manufacturer, but no more than 3 feet above the 
ground or crop canopy unless making a turf, pasture, or rangeland application, in which case 
applicators may apply with a nozzle height no more than 4 feet above the ground. 
x For applications prior to the emergence of crops and target weeds, applicators are required to use 
a Coarse or coarser droplet size (ASABE S572.1).

Q2M / Instigate® / MSTR /Notification with edits / 11-21-22 Page 25 
x For all other applications, applicators are required to use a Medium or coarser droplet size (ASABE 
S572.1). 
x DO NOT apply when wind speeds exceed 10 miles per hour at the application site. 
x DO NOT apply during temperature inversions. 
Boom-less Ground Applications: 
x Applicators are required to use a Medium or coarser droplet size (ASABE S572.1) for all 
applications. 
x DO NOT apply when wind speeds exceed 10 miles per hour at the application site. 
x DO NOT apply during temperature inversions.
Spray Drift Advisories 
Boo
m-less Ground Applications: 
x Setting nozzles at the lowest effective height will help to reduce the potential for spray drift. 
Handheld Technology Applications: 
x Take precautions to minimize spray drift. 
THE APPLICATOR IS RESPONSIBLE FOR AVOIDING OFF-SITE SPRAY DRIFT. BE AWARE OF 
NEARBY NON-TARGET SITES AND ENVIRONMENTAL CONDITIONS. 
Importance of Droplet Size 
An most effective way to reduce spray drift is to apply large droplets. Use the largest droplets that provide 
target pest control. While applying larger droplets will reduce spray drift, the potential for drift will be 
greater if applications are made improperly or under unfavorable environmental conditions. 
Controlling Droplet Size – Ground Boom 
x Volume - Increasing the spray volume so that larger droplets are produced will reduce spray drift. 
Use the highest practical spray volume for the application. If a greater spray volume is needed, 
consider using a nozzle with higher flow rate. 
x Pressure - Use the lowest spray pressure recommended for the nozzle to produce the target 
spray volume and droplet size. 
x Spray Nozzle - Use a spray nozzle that is designed for the intended application. Consider using 
nozzles designed to reduce drift. 
Controlling Droplet Size – Aircraft 
x Adjust Nozzles - Follow nozzle manufacturers recommendations for setting up nozzles. 
Generally, to reduce fine droplets, nozzles should be oriented parallel with the airflow in flight. 
Boom Height – Ground Boom 
Use the lowest boom height that is compatible with the spray nozzles that will provide uniform coverage. 
For ground equipment, the boom should remain level with the crop and have minimal bounce. 
Release Height – Aircraft 
Higher release heights increase the potential for spray drift. When applying aerially to crops, DO NOT 
release spray at a height greater than 10 ft above the crop canopy, unless a greater application height is 
necessary for pilot safety. 
Shielded Sprayers 
Shielding the boom or individual nozzles can reduce spray drift. Consider using shielded sprayers. Verify 
that the shields are not interfering with the uniform deposition of the spray on the target area.

Q2M / Instigate® / MSTR /Notification with edits / 11-21-22 Page 26 
Temperature And Humidity 
When making applications in hot and dry conditions, use larger droplets to reduce effects of evaporation. 
Temperature Inversions 
Drift potential is high during a temperature inversion. Temperature inversions are characterized by 
increasing temperature with altitude and are common on nights with limited cloud cover and light to no 
wind. The presence of an inversion can be indicated by ground fog or by the movement of smoke from a 
ground source or an aircraft smoke generator. Smoke that layers and moves laterally in a concentrated 
cloud (under low wind conditions) indicates an inversion, while smoke that moves upward and rapidly 
dissipates indicates good vertical air mixing. Avoid applications during temperature inversions. 
Wind 
Drift potential increases with wind speed. AVOID APPLICATIONS DURING GUSTY WIND CONDITIONS. 
Applicators need to be familiar with local wind patterns and terrain that could affect spray drift. 
Sensitive Areas 
Making applications when there is a sustained wind moving away from adjacent sensitive areas (e.g., 
residential areas, bodies of water, known habitat for threatened or endangered species, non-target crops) 
is an effective way to minimize the effect of spray drift. 
Drift Control Additives 
Using product compatible drift control additives can reduce drift potential. When a drift control additive is 
used, read and carefully observe cautionary statements and all other information on the additive’s label. If 
using an additive that increases viscosity, ensure that the nozzles and other application equipment will 
function properly with a viscous spray solution. Preferred drift control additives have been certified by the 
Chemical Producers and Distributors Association (CPDA). 
IDENTIFICATION INFORMATION FOR OTHER PRODUCTS INCLUDED IN THIS LABEL: 
USEPA REGISTERED PRODUCTS MENTIONED IN THIS LABEL FOR USE IN TANK MIXTURES 
OR OTHER REASONS 
PRODUCT BRAND NAME ACTIVE INGREDIENT(S) EPA REGISTRATION 
NUMBER 
Cinch® s-metolachlor 352-625
Cinch® ATZ s-metolachlor 352-624
Cinch ATZ Lite s-metolachlor 352-623
Surpass® NXT acetochlor 62719-672 
FulTime® NXT acetochlor + atrazine 62719-668 
Keystone® NXT acetochlor + atrazine 62719-671 
Keystone® LA NXT acetochlor + atrazine 62719-670 
Accent® Q nicosulfuron 352-773
Realm® Q rimsulfuron + mesotrione 352-837
Resolve® Q rimsulfuron + thifensulfuron-methyl 352-777
Revulin® Q nicosulfuron + mesotrione 352-900
Steadfast® Q nicosulfuron + rimsulfuron 352-774
Basis® Blend rimsulfuron + thifensulfuron-methyl 352-854
LeadOff® rimsulfuron + thifensulfuron-methyl 352-853
Prequel® isoxaflutole + rimsulfuron 352-779
NO
TICE TO BUYER: Purchase of this material does not confer any rights under patents of countries 
outside of the United States.

Q2M / Instigate® / MSTR /Notification with edits / 11-21-22 Page 27 
Limitation of Warranty and Liability 
NOTI
CE: Read this Limitation of Warranty and Liability before buying or using this product. DuPont will 
not be responsible for losses or damages resulting from the use of this product in any manner not 
specifically directed by DuPont. User assumes all risks associated with such non-directed use. If the 
terms are not acceptable, return the product at once, unopened, and the purchase price will be refunded. 
It is impossibl
e to eliminate all risks associated with the use of this product. Such risks arise from weather 
conditions, soil factors, off target movement, unconventional farming techniques, presence of other 
materials, the manner of use or application, or other unknown factors, all of which are beyond the control 
of DuPont. These risks can cause: ineffectiveness of the product, crop injury, or injury to non-target crops 
or plants. WHEN YOU BUY OR USE THIS PRODUCT, YOU AGREE TO ACCEPT THESE RISKS. 
DuPont warrants that this product conforms to the chemical descri
ption on the label thereof and is 
reasonably fit for the purpose stated in the Directions for Use, subject to the inherent risks described 
above, when used in accordance with the Directions for Use under normal conditions. 
TO THE EXTENT CONSISTENT WITH 
APPLICABLE LAW, DUPONT MAKES NO OTHER EXPRESS 
OR IMPLIED WARRANTY OF FITNESS OR OF MERCHANTABILITY OR ANY OTHER EXPRESS OR 
IMPLIED WARRANTY. TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, IN NO EVENT 
SHALL DUPONT OR SELLER BE LIABLE FOR ANY INCIDENTAL, CONSEQUENTIAL OR SPECIAL 
DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT. BUYER'S OR USER'S 
BARGAINED-FOR EXPECTATION IS CROP PROTECTION. TO THE EXTENT CONSISTENT WITH 
APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE USER OR BUYER AND THE EXCLUSIVE 
LIABILITY OF DUPONT OR SELLER, FOR ANY AND ALL CLAIMS, LOSSES, INJURIES OR DAMAGES 
(INCLUDING CLAIMS BASED ON BREACH OF WARRANTY OR CONTRACT, NEGLIGENCE, TORT 
OR STRICT LIABILITY), WHETHER FROM FAILURE TO PERFORM OR INJURY TO CROPS OR 
OTHER PLANTS, AND RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, SHALL BE 
THE RETURN OF THE PURCHASE PRICE OF THE PRODUCT, OR AT THE ELECTION OF DUPONT 
OR SELLER, THE REPLACEMENT OF THE PRODUCT. 
To the exte
nt consistent with applicable law that allows such requirement, DuPont or its Ag Retailer must 
have prompt notice of any claim so that an immediate inspection of buyer's or user's growing crops can 
be made. Buyer and all users shall promptly notify DuPont or a DuPont Ag Retailer of any claims, 
whether based on contract, negligence, strict liability, other tort or otherwise, or be barred from any 
remedy. 
This Limitatio
n of Warranty and Liability may not be amended by any oral or written agreement. 
Terms and Conditions of Use 
If terms of the following Warranty Disclaimer, Inherent Risks of Use, and Limitation of Remedies are not 
acceptable, return unopened package at once to the seller for a full refund of purchase price paid. To the 
extent consistent with applicable law, use by the buyer or any other user constitutes acceptance of the 
terms under Warranty Disclaimer, Inherent Risks of Use and Limitations of Remedies. 
 Warr
anty Disclaimer 
Corteva Agriscience warrants that this product conforms to the chemical description on the label and is 
reasonably fit for the purposes stated on the label when used in strict accordance with the directions for 
use, subject to the inherent risks set forth below. To the extent consistent with applicable law, Corteva 
Agriscience MAKES NO OTHER EXPRESS OR IMPLIED WARRANTY OF MERCHANTABILITY OR 
FITNESS FOR A PARTICULAR PURPOSE OR ANY OTHER EXPRESS OR IMPLIED WARRANTY.

Q2M / Instigate® / MSTR /Notification with edits / 11-21-22 Page 28 
Inherent Risks of Use 
It is impossible to eliminate all risks associated with use of this product. Plant injury, lack of performance, 
or other unintended consequences may result because of such factors as use of the product contrary to 
label instructions (including conditions noted on the label, such as unfavorable temperatures, soil 
conditions, etc.), abnormal conditions (such as excessive rainfall, drought, tornadoes, hurricanes), 
presence of other materials, the manner of application or other factors, all of which are beyond the control 
of Corteva Agriscience or the seller. To the extent consistent with applicable law, Corteva Agriscience will 
not be responsible for losses or damages resulting from the use of this product in any manner not 
specifically directed by Corteva Agriscience. To the extent consistent with applicable law, all such risks 
associated with non-directed use shall be assumed by buyer and/or user. 
Limitation of Remedies 
To the extent consistent with applicable law, the exclusive remedy for losses or damages resulting from 
this product (including claims based on contract, negligence, tort, strict liability, or other legal theories), 
shall be limited to, at Corteva Agriscience’s election, one of the following: 
1.
Refund of purchase price paid by buyer or user for product bought, or
2. Replacement of product used.
To the exte
nt consistent with applicable law, Corteva Agriscience shall not be liable for losses or 
damages resulting from handling or use of this product unless Corteva Agriscience is promptly notified of 
such loss or damage in writing. To the extent consistent with applicable law, in no case shall Corteva 
Agriscience be liable for consequential, incidental or special damages or losses. 
The term
s of the Warranty Disclaimer, Inherent Risks of Use, and Limitation of Remedies cannot be 
varied by any written or verbal statements or agreements. No employee or sales agent of Corteva 
Agriscience or the seller is authorized to vary or exceed the terms of the Warranty Disclaimer or this 
Limitation of Remedies in any manner. 
For 
product information call: 1-800-258-3033 
Produced for 
Corteva Agriscience LLC 
9330 Zionsville Road 
Indianapolis, IN 46268 
E. I. du Pont de Nemours and Company, Chestnut Run Plaza, 974 Centre Road, Wilmington, DE
19805 U.S.A.
™®Trademarks of Corteva Agriscience and its affiliated companies 
®™ Trademarks of Dow AgroSciences, DuPont or Pioneer and their affiliated companies or respective owners 
EPA accepted 04/23/21