crop-chem-docs/corpus/bayer/proline-480-sc.md

# Proline 480 SC Fungicide

- **Product class:** fungicide
- **EPA Reg No:** 264-825
- **Active ingredients:** Prothioconazole
- **Source:** https://www.cropscience.bayer.us/crop-protection/fungicide/proline-480-sc-fungicide
- **Label PDF:** https://cs-assets.bayer.com/is/content/bayer/Proline_480_SC1n_Fungicide_Labelpdf

---

Net
Contents:
2.5 Gallons
PROTHIOCONAZOLEGROUP 3 FUNGICIDE
4.50”
4.25”
7.75”
7.50”
COPY AREA
COPY AREA
For control of specified diseases on listed crops.
ACTIVE INGREDIENT:
Prothioconazole, 2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-
 2-hydroxypropyl]-1,2-dihydro-3H-1,2,4-triazole-3-thione    . . . . . . . 41.0%
OTHER INGREDIENTS:  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59.0%
Contains 4 pounds Prothioconazole per gallon   TOTAL:   100.0%
EPA Reg. No. 264-825
KEEP OUT OF REACH OF CHILDREN
CAUTION
For MEDICAL And TRANSPORTATION Emergencies ONLY
Call 24 Hours A Day 1-800-334-7577
For PRODUCT USE Information Call 1-866-99BAYER (1-866-992-2937)
Please refer to booklet for additional precautionary statements
and directions for use.
Produced for:
Bayer CropScience LP
800 N . Lindbergh Blvd .
St . Louis, MO 63167
PROLINE is a registered trademark of Bayer .
©2019 Bayer CropScience
US61380068C (190322C) PROLINE 480 SC  2 .5 GAL ETL  05/10/19
US61380068C             190322C  05/19

1
4 .50”
4 .0625”
7 .75”
7 .375”
COPY AREA
COPY AREA
FIRST AID
IF
SWALLOWED:
• Immediately call a poison control center or doctor for
treatment advice .
• Have person sip a glass of water if able to swallow .
• Do not induce vomiting unless told to do so by a poison
control center or doctor .
• Do not give anything by mouth to an unconscious person .
IF INHALED: • Move person to fresh air .
• If person is not breathing, call 911 or an ambulance, then give
artificial respiration, preferably mouth-to-mouth if possible .
• Call a poison control center or doctor for further treatment
advice .
IF ON SKIN
OR CLOTHING:
• Take off contaminated clothing .
• Rinse skin immediately with plenty of water for 15-20 minutes .
• Call a poison control center or doctor for treatment advice .
IF IN EYES: • Hold eye open and rinse slowly and gently with water for
15-20 minutes .
• Remove contact lenses, if present, after the first 5 minutes,
then continue rinsing eye .
• Call a poison control center or doctor for treatment advice .
For MEDICAL Emergencies Call 24 Hours A Day 1-800-334-7577.
Have the product container or label with you when calling a poison control
center or doctor or going for treatment.
NOTE TO PHYSICIAN:  No specific antidote .  Treat symptomatically .
PRECAUTIONARY STATEMENTS
HAZARD (TO HUMANS AND DOMESTIC ANIMALS)
CAUTION
Harmful if swallowed or inhaled .  Causes moderate eye irritation .  Avoid contact
with eyes and clothing .  Avoid breathing vapor or spray mist .  Wash thoroughly
with soap and water after handling and before eating, drinking, chewing gum, or
using tobacco . Remove and wash contaminated clothing before reuse .
Personal Protective Equipment
Applicators and other handlers must wear:
• Long-sleeved shirt and long pants
• Chemical resistant gloves made of any waterproof material
• Shoes plus socks
Follow manufacturer’s instructions for cleaning/maintaining PPE .   If no such
instructions exist for washables, use detergent and hot water  .  Keep and wash
PPE separately from other laundry .
Engineering Control Statements
When handlers use closed systems, enclosed cabs, or aircraft in a manner that
meets the requirements listed in the Worker Protection Standard (WPS) for
agricultural pesticides [40 CFR 170 .240(d)(4-6)], the handler PPE requirements
may be reduced or modified as specified in the WPS .

2
4 .50”
4 .0625”
7 .75”
7 .375”
COPY AREA
COPY AREA
User Safety Recommendations
Users should:
• Wash hands before eating, drinking, chewing gum, using tobacco, or using the
toilet .
• Remove clothing/PPE immediately if pesticide gets inside  . Then wash
thoroughly and put on clean clothing .
• Remove PPE immediately after handling this product .  Wash the outside of
gloves before removing . As soon as possible, wash thoroughly and change
into clean clothing .
ENVIRONMENTAL HAZARDS
This product is toxic to estuarine/marine invertebrates, and freshwater/estuaries/
marine aquatic plants .  Do not apply directly to water, or to areas where surface
water is present or to intertidal areas below the mean high water mark .   Do not
contaminate water when disposing of equipment washwater or rinsate .
Prothioconazole-desthio (a degradate of prothioconazole) is known to leach
through soil into ground water under certain conditions as a result of label use  .
Use of this chemical in areas where soils are permeable, particularly where the
water table is shallow, may result in ground-water contamination .
Drift and runoff are hazardous to aquatic organisms in water adjacent to treated
areas .  This product has a high potential for runoff for several months or more
after application .  Poorly draining soils and soils with shallow water tables are
more prone to produce runoff that contains this product . A level, well maintained
vegetative buffer strip between areas to which this product is applied and surface
water features such as ponds, streams, and springs will reduce the potential for
contamination of water from rainfall-runoff .  Runoff of this product will be reduced
by avoiding applications when rainfall is forecasted to occur within 48 hours .
DIRECTIONS FOR USE
It is a violation of federal law to use this product in a manner
inconsistent with its labeling.
Do not apply this product in a way that will contact workers or other  persons, either
directly or through drift .   Only protected handlers may be in the area during
application .  For any requirements specific to your State or Tribe, consult the
agency responsible for pesticide regulation .
AGRICULTURAL USE REQUIREMENTS
Use this product only in accordance with its labeling and with the Worker
Protection Standard, 40 CFR part 170 .  This Standard contains requirements
for the protection of agricultural workers on farms, forests, nurseries, and
greenhouses, and handlers of agricultural pesticides .  It contains requirements
for training, decontamination, notification, and emergency assistance .  It also
contains specific instructions and exceptions pertaining to the statements on
this label about personal protective equipment (PPE) and restricted-entry
interval and notification to workers (as applicable) .   The requirements in
this box only apply to uses of this product that are covered by the Worker
Protection Standard .
Do not enter or allow worker entry into treated areas during the restricted-
entry interval (REI) of 12 hours .
PPE required for early entry to treated areas that is permitted under the
Worker Protection Standard and that involves contact with anything that has
been treated, such as plants, soil, or water is:
• Coveralls
• Chemical-resistant gloves made of any waterproof material .
• Shoes plus socks

3
4 .50”
4 .0625”
7 .75”
7 .375”
COPY AREA
COPY AREA
PRODUCT INFORMATION
PROLINE® 480 SC Fungicide is a broad-spectrum systemic fungicide for the
control of Ascomycetes, Basidiomycetes and Deuteromycetes diseases in a
variety of crops including barley, buckwheat, bushberry subgroup, low growing
berry subgroup (except strawberry), corn, cotton, cucurbit vegetables, dry shelled
pea and bean crop subgroup, millet, oats, peanuts, rapeseed subgroup 20A
(including canola and Brassica carinata), rye, soybean, sugar beets, triticale,
wheat; conifer and hardwood nursery seeds and seedlings  . Under conditions
conducive to extended infection periods or high disease pressure, additional
fungicide applications beyond the number allowed by this label may be needed .
Under these conditions use another fungicide registered for the crop/disease  .
Equipment must be properly calibrated before use .
FUNGICIDE RESISTANCE MANAGEMENT (FRAC) RECOMMENDATIONS
For resistance management, PROLINE 480 SC Fungicide contains a Group 3
fungicide . Any fungal population may contain individuals naturally resistant to
PROLINE 480 SC Fungicide and other Group 3 fungicides . A gradual or total loss of
pest control may occur over time if these fungicides are used repeatedly in the same
fields . Appropriate resistance-management strategies should be followed .
To delay fungicide resistance, take one or more of the following steps:
• Rotate the use of PROLINE 480 SC Fungicide or other Group 3 fungicides within
a growing season sequence with different groups that control the same pathogens .
• Use tank mixtures with fungicide from a different group that are equally effective on
the target pest when such use is permitted . Use at least the minimum application
rate as labeled by the manufacturer .
• Adopt an integrated disease management program for fungicide use that includes
scouting, uses historical information related to pesticide use, and crop rotation,
and which considers host plant resistance, impact of environmental conditions on
disease development, disease thresholds, as well as cultural, biological and other
chemical control practices .
• Where possible, make use of predictive disease models to effectively time fungicide
applications . Note that using predictive models alone is not sufficient to manage
resistance .
• Monitor treated fungal/bacterial populations for resistance development .
• Contact your local extension specialist or certified crop advisor for any additional
pesticide resistance-management and/or IPM recommendations for specific crops
and pathogens .
• For further information or to report suspected resistance contact Bayer
CropScience at 1-866-99BAYER (1-866-992-2937) . Y ou can also contact your
pesticide distributor or university extension specialist to report resistance .
Spray Equipment/Volumes
PROLINE 480 SC Fungicide may be applied by either ground, aerial and/or
chemigation application equipment .  Refer to the USE DIRECTIONS FOR SPECIFIC
CROPS section of this label for approved applications for each crop .
Apply in a minimum of 10 gallons of spray solution per acre by ground sprayer . Apply
in a minimum of 5 gallons of spray solution per acre by aircraft spray equipment
unless stated differently elsewhere in this label .   Check equipment calibration
frequently .  Complete coverage and uniform application are essential for the most
effective results, especially when lower spray volumes are applied .  If necessary,
increase the spray volume per acre for complete crop coverage .
Mixing Procedures
It is the pesticide user’s responsibility to ensure that all products are registered for
the intended use  . Read and follow the applicable restrictions and limitations and
directions for use on all product labels involved in tank mixing . Users must follow the
most restrictive directions for use and precautionary statements of each product in
the tank mixture . (continued)

4
4 .50”
4 .0625”
7 .75”
7 .375”
COPY AREA
COPY AREA
Prepare no more spray mixture than is necessary for the immediate operation .
Thoroughly clean spray equipment before using this product . Maintain maximum
agitation throughout the spray operation .   Do not let the spray mixture stand
overnight in the spray tank .  Flush the spray equipment thoroughly following each
use and apply the rinsate to the previously treated area or dispose of the rinsate
according to local regulations .
PROLINE 480 SC Fungicide Alone:  Add 1/2 of the required amount of water to
the mix tank .  With the agitator running, add the PROLINE 480 SC Fungicide to the
tank .  Continue agitation while adding the remainder of the water .  Begin application
of the solution after the product has completely and uniformly dispersed into the mix
water .  Maintain agitation until all of the mixture has been applied .
PROLINE 480 SC Fungicide + Tank-Mix Partners:  Add 1/2 of the required amount
of water to the mix tank .  Start the agitator running before adding any of the tank-mix
partners .  In general, tank-mix partners should be added in this order: products
packaged in water-soluble packaging, wettable powders, wettable granules (dry
flowables), liquid flowables, liquids, and emulsifiable concentrates  . Always allow
each tank-mix partner to become fully and uniformly dispersed before adding the
next product .  Provide sufficient agitation while adding the remainder of the water .
Maintain agitation until all of the mixture has been applied .
When using PROLINE 480 SC Fungicide in tank mixtures, all products in water-
soluble packaging should be added to the tank before any other tank-mix partner,
including PROLINE 480 SC Fungicide  .  Allow the water-soluble packaging to
completely disperse before adding any other tank-mix partner to the tank .
If using PROLINE 480 SC Fungicide in a tank mixture, observe all directions for use,
crop/sites, use rates, dilution ratios, precautions, and limitations; which appear on
the tank-mix product label .  No label dosage rate must be exceeded, and the most
restrictive label precautions and limitations must be followed .  This product must
not be mixed with any product that prohibits such mixing .  Tank mixtures or other
applications of products are permitted only in those states in which the products
are registered .
PROLINE 480 SC Fungicide is compatible with most insecticide, fungicide,
herbicide, and foliar nutrient products  .  However, the physical compatibility of
PROLINE 480 SC Fungicide with tank-mix partners should be tested before use  .
To determine the physical compatibility of PROLINE 480 SC Fungicide with other
products, use a jar test, as described below .
Using a quart jar, add the proportionate amounts of the products to 1 qt . of water .
Add wettable powders and water-dispersible granular products first, then liquids,
and emulsifiable concentrates last .  After thoroughly mixing, let stand for at least 5
minutes .  If the combination remains mixed or can be remixed readily, it is physically
compatible .  Once compatibility has been proven, use the same procedure for
adding required ingredients to the spray tank . For further information, contact your
local Bayer CropScience representative .
The crop safety of all potential tank mixes including additives and other pesticides
on all crops has not been tested .  Before applying any tank mixture not specifically
recommended on this label, the safety to the target crop should be confirmed .  To
test for crop safety, apply PROLINE 480 SC Fungicide to the target crop in a small
area and in accordance with label instructions for the target crop .
Soilborne/Seedling Disease Control
PROLINE 480 SC Fungicide can provide control of certain soilborne/seedling
diseases when applied as an in-furrow application at time of planting or as a
banded application applied over the row at time of planting and up to row closure
on certain crops . Refer to the USE DIRECTIONS FOR SPECIFIC CROPS section
of the label to determine which crops contain recommendations for in-furrow and/
or banded applications and for the optimal timings, rates and band widths of these
applications .

5
4 .50”
4 .0625”
7 .75”
7 .375”
COPY AREA
COPY AREA
In-Furrow Application
• Apply PROLINE 480 SC Fungicide as an in-furrow application in 2 .5 to 20 gallons
of water at planting .
• Mount the spray nozzle such that the spray is directed into the furrow just before
the seeds are covered .
Banded Application
• Apply PROLINE 480 SC Fungicide as a directed spray to the soil, using single or
multiple nozzles which can be adjusted to provide uniform coverage of the lower
stems and the soil surface surrounding the plants .
Rate per
1000
Row Feet
RATE OF PROLINE 48O SC FUNGICIDE FOR IN-FURROW
AND BANDED APPLICATIONS
(fl oz per acre)
fl oz
product
15”
rows
20”
rows
22”
rows
30”
rows
32”
rows
34”
rows
36”
rows
38”
rows
40”
rows
0.075 2.61
0.100 3.48 2.61
0.125 4.36 3.27 2.97
0.150 5.23 3.92 3.56 2.61
0.175 6.10 4.57 4.16 3.05 2.86 2.69
0.200 6.97 5.23 4.75 3.48 3.27 3.07 2.90 2.75 2.61
0.225 5.88 5.35 3.92 3.68 3.46 3.27 3.10 2.94
0.250 6.53 5.94 4.36 4.08 3.84 3.63 3.44 3.27
0.275 6.53 4.79 4.49 4.23 3.99 3.78 3.59
0.300 5.23 4.90 4.61 4.36 4.13 3.92
0.325 5.66 5.31 5.00 4.72 4.47 4.25
0.350 6.10 5.72 5.38 5.08 4.81 4.57
0.375 6.53 6.13 5.77 5.45 5.16 4.90
0.400 6.97 6.53 6.15 5.81 5.50 5.23
0.425 6.94 6.53 6.17 5.85 5.55
0.450 6.92 6.53 6.19 5.88
0.475 6.90 6.53 6.21
0.500 6.88 6.53
0.525 6.86
0.543 7.10
Aerial Application: Avoid application under conditions when uniform coverage
cannot be obtained or when excessive spray drift may occur .  Do not apply directly
to humans or animals .
Chemigation Application:  Apply PROLINE 480 SC Fungicide through irrigation
equipment only to crops for which chemigation is specified on this label .
PROLINE 480 SC Fungicide alone or in combination with other pesticides, which
are registered for application through irrigation systems, may be applied through
irrigation systems . Apply this product only through center pivot, solid set, drip,
linear, or moving wheel irrigation systems . Do not apply this product through any
other type of irrigation system . Illegal pesticide residues in the crop can result from
nonuniform distribution of treated water . If you have questions about calibration, you
should contact State Extension Service specialists, equipment manufacturers, or
other experts . Do not connect an irrigation system (including greenhouse systems)
used for pesticide application to a public water system, unless the pesticide
label-prescribed safety devices for public water systems are in place  . A person
knowledgeable of the chemigation system and responsible for its operation, or
under the supervision of the responsible person, shall shut the system down and
make necessary adjustments should the need arise .

6
4 .50”
4 .0625”
7 .75”
7 .375”
COPY AREA
COPY AREA
Operating Instructions
1 . The system must contain a functional check-valve, vacuum relief valve, and low-
pressure drain appropriately located on the irrigation pipeline to prevent water-
source contamination from backflow .
2 . The pesticide injection pipeline must contain a functional, automatic, quick-closing
check-valve to prevent the flow of fluid back toward the injection pump .
3 . The pesticide injection pipeline must also contain a functional, normally closed,
solenoid-operated valve located on the intake side of the injection pump and
connected to the system interlock to prevent fluid from being withdrawn from the
supply tank when the irrigation system is either automatically or manually shut down .
4 . The system must contain functional interlocking controls to automatically shut off
the pesticide injection pump when the water pump motor stops .
5 . The irrigation line or water pump must include a functional pressure switch, which
will stop the water pump motor when the water pressure decreases to the point
where pesticide distribution is adversely affected .
6 . Systems must use a metering pump, such as a positive displacement injection
pump (e .g ., diaphragm pump), effectively designed, and constructed of materials
that are compatible with pesticides and capable of being fitted with a system
interlock .
7 . Do not apply when wind speed favors drift beyond the area intended .
Center Pivot Irrigation Equipment
Notes: (1) Use only with drive systems, which provide uniform water distribution . (2)
Do not use end guns when chemigating PROLINE 480 SC Fungicide through center
pivot systems because of non-uniform application .
Determine the size of the area to be treated . Determine the time required to apply
1/8-1/2 inch of water over the area to be treated when the system and injection
equipment are operated at normal pressures as recommended by the equipment
manufacturer . When applying PROLINE 480 SC Fungicide through irrigation
equipment use the lowest obtainable water volume while maintaining uniform
distribution . Run the system at 80-95% of the manufacturer’s rated capacity . Using
water, determine the injection pump output when operated at normal line pressure .
Determine the amount of PROLINE 480 SC Fungicide required to treat the area
covered by the irrigation system . Add the required amount of PROLINE 480 SC
Fungicide and sufficient water to meet the injection time requirements to the solution
tank . Make sure the system is fully charged with water before starting injection of the
PROLINE 480 SC Fungicide solution . Time the injection to last at least as long as it
takes to bring the system to full pressure . Maintain constant solution tank agitation
during the injection period . Continue to operate the system until the PROLINE 480
SC Fungicide solution has cleared the sprinkler head .
Solid Set and Moving Wheel Irrigation Equipment
When applying PROLINE 480 SC Fungicide through irrigation equipment use the
lowest obtainable water volume while maintaining uniform distribution . Determine
the amount of PROLINE 480 SC Fungicide required to treat the area covered by the
irrigation system . Add the required amount of PROLINE 480 SC Fungicide into the
same quantity of water used to calibrate the injection period . Operate the system at
the same pressure and time interval established during the calibration . Stop injection
equipment after treatment is completed . Continue to operate the system until the
PROLINE 480 SC Fungicide solution has cleared the last sprinkler head .
Using Water from Public Water Systems
Public water system means a system for the provision to the public of piped water for
human consumption if such system has at least 15 service connections or regularly
serves an average of at least 25 individuals daily at least 60 days out of the year  .
Chemigation systems connected to public water systems must contain a functional,
(continued)

7
4 .50”
4 .0625”
7 .75”
7 .375”
COPY AREA
COPY AREA
reduced-pressure zone (RPZ), back flow preventer or the functional equivalent in
the water supply line upstream from the point of pesticide introduction . As an option
to the RPZ, the water from the public water system should be discharged into a
reservoir tank prior to pesticide introduction . There shall be a complete physical
break (air gap) between the flow outlet end of the fill pipe and the top or overflow
rim of the reservoir tank of at least twice the inside diameter of the fill pipe  . The
pesticide injection pipeline must contain a functional, automatic, quick-closing check
valve to prevent the flow of fluid back toward the injection . The pesticide injection
pipeline must contain a functional, normally closed, solenoid-operated valve located
on the intake side of the injection pump and connected to the system interlock to
prevent fluid from being withdrawn from the supply tank when the irrigation system
is either automatically or manually shut down . The system must contain functional
interlocking controls to automatically shut off the pesticide injection pump when the
water pump motor stops or in cases where there is no water pump, when the water
pressure decreases to the point where pesticide distribution is adversely affected .
Systems must use a metering pump, such as a positive displacement injection
pump (e .g ., diaphragm pump) effectively designed and constructed of materials that
are compatible with pesticides and capable of being fitted with a system interlock .
Adjuvants: PROLINE 480 SC Fungicide is recommended to be used with a
registered non-ionic surfactant at the lowest recommended labeled rate for most
crops .  Refer to the individual crop recommendations for those specific uses where
a surfactant is not recommended .
Recommendations to Avoid Spray Drift
Do not make applications when conditions favor drift beyond the target application
area .  When drift may be a problem, take measures to reduce drift, including:
1 . Do not spray if wind speeds are or become excessive .  Do not spray if wind speed
is 15 mph or greater .  If non-target crops are located downwind, use caution when
spraying if wind is present .  Do not spray if winds are gusty .
2 . Use caution when conditions are favorable for drift (high temperatures, drought,
and low relative humidity) .
3 . Do not apply when temperature inversion exists  .  If inversion conditions are
suspected, consult with local weather services before making an application .
ROTATIONAL RESTRICTIONS
Treated areas may be replanted with any crop specified on this label as soon as
practical after last application .  For crops not listed on this label, do not plant back
within 30 days of last application .

8
4 .50”
4 .0625”
7 .75”
7 .375”
COPY AREA
COPY AREA
USE DIRECTIONS FOR SPECIFIC CROPS
PROLINE 480 SC Fungicide provides control or suppression of many important
diseases of barley, buckwheat, bushberry subgroup, low growing berry subgroup
(except strawberry), corn, cotton, cucurbit vegetables, dry shelled pea and bean
crop subgroup, millet, oats, peanuts, rapeseed subgroup 20A (including canola
and Brassica carinata), rye, soybean, sugar beets, triticale, wheat; conifer and
hardwood nursery seeds and seedlings  . When reference is made to disease
suppression, suppression can mean either erratic control from good to fair or
consistent control at a level below that obtained with the best commercial disease
control products .
APPLICATION DIRECTIONS
CROP DISEASE CONTROLLED
RATE OF PROLINE
480 SC Fungicide
Barley Fusarium Head Blight (Fusarium spp .)
(Suppression Only)
5 .0 - 5 .7 fl oz/A
(0 .156 - 0 .178 lbs ai/A)
Leaf and Stem Diseases
Net Blotch (Pyrenophora teres)
Powdery Mildew (Blumeria graminis f. sp. hordei)
Rusts (Puccinia spp .)
Scald (Rhynchosporium secalis)
Spot Blotch (Cochliobolus sativus)
2 .8 - 4 .3 fl oz/A
(0 .088 - 0 .134 lbs ai/A)
PROLINE 480 SC Fungicide may be applied by either ground, aerial or
chemigation application equipment .
For aerial applications made prior to heading (prior to Feekes Growth Stage
10 .5), apply a minimum of 2 gpa spray solution .  For aerial applications made
at the heading growth stage or later, apply in a minimum of 5 gpa spray solution .
Chemigation use is allowed only for applications made prior to heading .
Fusarium Head Blight (Suppression Only): The optimal time to apply PROLINE
480 SC Fungicide is as a preventative foliar spray when barley heads on the
main stem are fully emerged (~ Feekes Growth Stages 10 .5) .  Spray equipment
must be set to provide good coverage to barley heads .  For thorough coverage
of barley head using ground application equipment, it is recommended to use
forward and backward mounted nozzles or nozzles that have a two-directional
spray . Nozzles should be operated within the spray pressure directions suggested
by the manufacturer .
Leaf and Stem Diseases:  Apply PROLINE 480 SC Fungicide as a preventive
foliar spray when the earliest disease symptoms appear on the leaves or stems .
Barley fields should be observed closely for early disease symptoms, particularly
when susceptible varieties are planted and/or under prolonged conditions
favorable for disease development .
Other Requirements: Apply up to two (2) applications of PROLINE 480 SC Fungicide per
year .  Repeat applications using a 14-day spray interval if conditions remain favorable for
continued or increasing disease development . For optimum disease control, the lowest labeled
rate of a spray surfactant should be tank mixed with PROLINE 480 SC Fungicide .
A maximum of 9 .37 fl oz (0 .293 lbs prothioconazole) of PROLINE 480 SC Fungicide may be
applied per acre per year .  Do not apply within 32 days of harvest .

9
4 .50”
4 .0625”
7 .75”
7 .375”
COPY AREA
COPY AREA
APPLICATION DIRECTIONS
CROP DISEASES CONTROLLED
RATE OF PROLINE
480 SC FUNGICIDE
Bushberry subgroup
(Subgroup 13-07B):
Aronia berry; blueberry
(highbush and lowbush);
Chilean guava; highbush
cranberry; currant
(black, buffalo, and red);
elderberry; European
barberry; gooseberry;
edible honeysuckle;
huckleberry; jostaberry;
juneberry (Saskatoon
berry); lingonberry;
native currant; salal; sea
buckthorn; and cultivars,
varieties, and/or hybrids
of these .
Septoria leaf spot (Septoria spp .)
Monilinia blight
 (Monilinia vaccinii-corymbosi)
Valdensinia leaf spot
 (Valdensinia heterodoxa)
Leaf rust (Thekopsora minima)
Anthracnose
 (Colletotrichum gloeosporioides)
Botrytis blight (Botrytis cinerea)
Phomopsis canker and twig blight1
 (Phomopsis vaccinii)
Alternaria fruit rot1 (Alternaria spp .)
White pine blister rust1
 (Cronartium ribicola)
5 .7 fl oz/A
(0 .178 lbs ai/A)
PROLINE 480 SC Fungicide may be applied by either ground
or chemigation application equipment . Apply PROLINE 480 SC
Fungicide at the first sign of disease .
Other Requirements: Apply up to two (2) applications of PROLINE 480 SC Fungicide
per year .  Repeat applications as needed using a 7- to 10-day spray interval if conditions
remain favorable for continued or increasing disease development .
A maximum of 11 .4 fl oz (0 .356 lbs prothioconazole) of PROLINE 480 SC Fungicide may
be applied per acre per year  .  Do not apply within 7 days of harvest .
1 Not Registered for use in California .
APPLICATION DIRECTIONS
 CROP DISEASES CONTROLLED
RATE OF PROLINE
480 SC FUNGICIDE
Low growing berry
subgroup, except
strawberry1:
Bearberry; bilberry;
cloudberry; cranberry;
muntries; partridgeberry;
and cultivars, varieties,
and/or hybrids of these
Fruit rot:
Coleophoma empetri
Glomerella cingulata
Phyllosticta vaccinii
Physalospora vaccinii
Allantophomopsis lycopodina
Allantophomopsis cytisporea
Fusicoccum putrefaciens
Penicillium spp .
Phomopsis vaccinii
Colletotrichum acutatum
Botrytis spp .
Monilinia spp .
Valdensinia leaf spot
 (Valdensinia heterodoxa)
5 .0 fl oz/A
(0 .156 lbs ai/A)
PROLINE 480 SC Fungicide may be applied by either ground or
chemigation application equipment . For best control of fruit rots
begin applications at early bloom . Make a second application
of PROLINE 480 SC Fungicide or another approved fungicide
7-10 days later .
Other Requirements: Apply up to two (2) applications of PROLINE 480 SC Fungicide
per year .  Repeat applications as needed using a 7- to 10-day spray interval if conditions
remain favorable for continued or increasing disease development .
A maximum of 10 .0 fl oz (0 .313 lbs prothioconazole) of PROLINE 480 SC Fungicide may
be applied per acre per year  .  Do not apply within 45 days of harvest .
1 Not Registered for use in California .

10
4 .50”
4 .0625”
7 .75”
7 .375”
COPY AREA
COPY AREA
APPLICATION DIRECTIONS
CROP DISEASES CONTROLLED
RATE OF PROLINE
480 SC Fungicide
Buckwheat
Millet, pearl
Millet, proso
Oats
Rye
Rusts
  (Puccinia spp .)
Glume Blotch
  (Stagonospora nodorum)
Head Blight or Scab
  (Fusarium graminearum) – Suppression
Powdery Mildew
  (Erysiphe graminis)
Scald
  (Rynchosporium secalis)
Speckled Blotch
  (Septoria avenae; Septoria tritici)
Spot Blotch
  (Bipolaris sorokiniana)
Tan Spot or Y ellow leaf Spot
  (Pyrenophora tritici-repentis)
5 - 5 .7  fl oz/A
(0 .156 to 0 .178 lbs ai/A)
Apply PROLINE 480 SC Fungicide as a preventive foliar spray when the
earliest disease symptoms appear on the leaves or stems . Fields should
be observed closely for early disease symptoms, particularly when
susceptible varieties are planted and/or under prolonged conditions
favorable for disease development .
Other Requirements: Apply only one application per year  . Applications may be made by
ground or aerial spray equipment . A maximum of 5 .7 fl oz (0 .178 lbs prothioconazole) of
PROLINE 480 SC Fungicide may be applied per acre per year . Do not apply within 30 days
of harvest .

11
4 .50”
4 .0625”
7 .75”
7 .375”
COPY AREA
COPY AREA
APPLICATION DIRECTIONS
CROP DISEASE CONTROLLED
RATE OF
PROLINE 480
SC Fungicide APPLICATION TIMING
Corn (field corn,
field corn grown
for seed and
popcorn)
Anthracnose Leaf Blight
 (Colletotrichum graminicola)
Eye spot
  (Aureobasidium zeae)
Gray leaf spot
  (Cercospora zeae-maydis)
Northern Corn Leaf Blight
 (Setosphaeria turcica)1
Northern Corn Leaf Spot
 (Cochliobolus carbonum)1
Rust (Puccinia spp .)
Southern Corn Leaf Blight
 (Cochliobolus heterostrophus)1
5 .7 fl oz/A
(0 .178 lbs ai/A)
Apply PROLINE
480 SC Fungicide at
the first sign of disease .
Repeat applications as
needed on a 7 – to 14-
day interval if favorable
conditions for disease
development persist .
Do not use adjuvants
in sprays made
between V8 (8 leaf
collar) and VT (lowest
branch of the tassel
is visible but the silks
have not yet emerged) .
For the suppression of:
Fusarium2, Gibberella2
and Aspergillus2 ear rots
(Fusarium spp ., Gibberella
spp . and Aspergillus spp .)
5 .7 fl oz per acre
(0 .178 lbs ai/A)
For optimum
suppression of
Fusarium, Gibberella
and Aspergillus ear
rots, apply PROLINE
480 SC Fungicide
from the R1 (initial
silk emergence) to
the R2 (brown silk)
corn growth stages .
PROLINE 480 SC
Fungicide will reduce
both disease symptoms
and levels of mycotoxin
in the grain .
Soilborne/Seedling Diseases:
Rhizoctonia root2 and stalk rot2
  (Rhizoctonia solani)
2 .6 - 4 .0 fl oz per
acre
(0 .081 - 0 .125
lbs ai/A)
In furrow application
for soilborne/seedling
disease control, see
use directions and
rate chart for various
row spacing under
the SOILBORNE/
SEEDLING DISEASE
CONTROL Section .
Other requirements:  PROLINE 480 SC Fungicide may be applied by either ground, aerial or
chemigation application equipment .
For aerial applications, apply PROLINE 480 SC Fungicide using a minimum of 3 gpa spray
solution . An adjuvant may be used to improve spray coverage . Refer to the adjuvant product
label for specific use directions .
Application of PROLINE 480 SC Fungicide is not recommended at times when corn is under
severe environmental stress conditions .  Do not exceed 22 .8 fl oz (0 .713 lbs prothioconazole)
total from all uses, including soil and foliar applications, per acre of PROLINE 480 SC
Fungicide per year . Do not apply within 14 days of harvest for grain and fodder .
Forage may be harvested the same day of application .
1The above diseases are also known as Helminthosporium leaf blights
2Not registered for use in California .

12
4 .50”
4 .0625”
7 .75”
7 .375”
COPY AREA
COPY AREA
APPLICATION DIRECTIONS
CROP DISEASES SUPPRESSED
RATE OF PROLINE
480 SC FUNGICIDE
Cotton In furrow and Banded
Damping off
(Rhizoctonia solani)
Fusarium Wilt1
(Fusarium spp .)
5 .7 - 7 .1 fl oz/A
(0 .178 - 0 .222 lbs ai/A)
(0 .4 - 0 .5 fl oz per 1000
row feet)
Foliar
Target Spot
(Corynespora cassiicola)
Rust
(Puccinia spp .)
5 .0 - 5 .7 fl oz/A
(0 .156 - 0 .178 lbs ai/A)
Application Directions:
For foliar applications:  PROLINE 480 SC Fungicide may be applied by
ground, aerial, or chemigation application equipment .
For in-furrow applications: Apply 5 .7 to 7 .1 fl oz per acre (0 .393 to 0 .489
fl oz per 1000 row feet if on 36 inch row spacing) in the furrow at planting .
For banded applications: PROLINE 480 SC Fungicide may also be applied
in a 4- to 6- inch band over the row at or near emergence .
General Comments:  When used at 5 .0 to 5 .7 fl oz per acre, do not apply more than three (3)
applications of PROLINE 480 SC Fungicide per year including the in-furrow, banded and foliar
applications . If any application is made at a rate above 5 .7 fl oz per acre, do not make more
than two (2) total applications of PROLINE 480 SC Fungicide per year including in-furrow,
banded, and foliar applications . Repeat applications as needed using a 14-day spray interval
if conditions remain favorable for continued or increasing disease development . A maximum
of 17 .1 fl oz (0 .534 lbs prothioconazole) of PROLINE 480 SC Fungicide may be applied per
acre per year including all soil and foliar applications .  Do not apply within 30 days of harvest .
1Not registered for use in California .
APPLICATION DIRECTIONS
CROP DISEASE CONTROLLED
RATE OF PROLINE
480 SC Fungicide
Chickpea Ascochyta Blight (Ascochyta spp .) 5 .0 - 5 .7 fl oz/A
(0 .156 - 0 .178 lb ai/A)
PROLINE 480 SC Fungicide may be applied by either ground, aerial or
chemigation application equipment .
Apply PROLINE 480 SC Fungicide at the first sign of disease  .  Use the
higher use rate when conditions are favorable for severe disease pressure
and/or when growing susceptible varieties .
Other Requirements:  Apply up to three (3) applications of PROLINE 480 SC Fungicide
per year .  Repeat applications as needed using a 10- to 14-day spray interval if conditions
remain favorable for continued or increasing disease development .  To optimize disease
control, the lowest labeled rate of a spray surfactant should be tank-mixed with PROLINE
480 SC Fungicide .
A maximum of 17 .1 fl oz (0 .534 lbs prothioconazole) of PROLINE 480 SC Fungicide may be
applied per acre per year .  Allow a minimum of 7 days from the last application until cutting or
swathing the crop for harvest .

13
4 .50”
4 .0625”
7 .75”
7 .375”
COPY AREA
COPY AREA
APPLICATION DIRECTIONS
CROP
DISEASES
CONTROLLED
RATE OF PROLINE
480 SC FUNGICIDE
Cucurbit vegetables  (Crop Group 9):
Chayote (fruit); Chinese waxgourd
(Chinese preserving melon); citron
melon; cucumber; gherkin; edible
gourd (includes hyotan, cucuzza,
hechima, Chinese okra); Momordica
spp (includes balsam apple, balsam
pear, bittermelon, Chinese cucumber);
muskmelon (includes true cantaloupe,
cantaloupe, casaba, Crenshaw melon,
golden pershaw melon, honeydew
melon, honey balls, mango melon,
Persian melon, pineapple melon,
Santa Claus melon, and snake
melon); pumpkin; squash (summer
and winter, includes crookneck
squash, scallop squash, straightneck
squash, vegetable marrow, zucchini,
butternut squash, calabaza, hubbard
squash, acorn squash, spaghetti
squash); watermelon
Fusarium wilt
Fusarium blight
 (Fusarium oxysporum)
 (Fusarium spp .)
Gummy stem blight
 (Didymella spp .)
Southern blight1
 (Sclerotium roflsii)
Powdery mildew
 (Sphaerotheca fuliginea /
 Podosphaera xanthii)
 (Erysiphe cichoracearum)
5 .7 fl oz/A
(0 .178 lbs ai/A)
(soil)
5 .7 fl oz/A
(0 .178 lbs ai/A)
(foliar)
PROLINE 480 SC Fungicide may be applied by
either ground or chemigation application equipment
(including drip irrigation) .  Do not use in water used
for hand transplanting .  Not for use in greenhouse/
transplant house .
Other Requirements: Apply up to one (1) soil application and two (2) foliar applications of
PROLINE 480 SC Fungicide per year .  Repeat applications as needed using a 5- to 10-day
spray interval if conditions remain favorable for continued or increasing disease development .
A maximum of 17 .1 fl oz (0 .534 lbs prothioconazole) of PROLINE 480 SC Fungicide may be
applied per acre per year .  Do not apply within 7 days of harvest .
1Not registered for use in California .
APPLICATION DIRECTIONS
CROP
DISEASE
CONTROLLED
RATE OF PROLINE
480 SC Fungicide
Dried Shelled Peas and Beans
Subgroup (except soybeans)
Lupinus spp . (Grain, Sweet, White
 and White Sweet lupins)
Phaseolus spp . (Field, Kidney,
 Dry lima, Navy, Pinto and Tepary
 beans)
Vigna spp . (Adzuki bean,
 Blackeyed pea, Catjang, Cowpea,
 Crowder pea, Moth bean, Mung
 bean, Rice bean, Southern pea
 and Urd bean)
Dry broad bean
Guar
Lablab bean
Pisum spp . Pea (including Field
 pea) and Pigeon pea
Foliar
5 .7 fl oz/A
(0 .178 lbs ai/A)Ascochyta Blight
  (Ascochyta pinodes)
Rust (Uromyces appendiculatus)
White Mold
  (Sclerotinia sclerotiorum)
In Furrow
 2 .6 - 5 .0 fl oz/A
(0 .081 - 0 .156 lbs ai/A)Rhizoctonia rots1
 (Rhizoctonia spp .)
PROLINE 480 SC Fungicide may be applied by either
ground, aerial or chemigation application equipment .  For
ground applications, apply in a minimum of 20 gpa .
In-furrow use: Apply up to 5 .0 fl oz per acre (0 .288 fl oz
per 1000 row feet if on 30 inch row spacing; 0 .192 fl oz per
1000 row feet if on a 20 inch row spacing) in the furrow
at planting . See use directions and rate chart for various
row spacing under the SOILBORNE/SEEDLING DISEASE
CONTROL section .
For rust control, apply PROLINE 480 SC Fungicide at the
first sign of disease . For white mold control, apply PROLINE
480 SC Fungicide at 25% flower .
Other Requirements: Apply up to three (3) applications of PROLINE 480 SC Fungicide per
year .  Repeat applications as needed using a 5- to 14-day spray interval if conditions remain
favorable for continued or increasing disease development . To optimize disease control, the
lowest labeled rate of a spray surfactant should be tank-mixed with PROLINE 480 SC Fungicide .
A maximum of 17 .1 fl oz of PROLINE 480 SC Fungicide (0 .534 lbs prothioconazole) may be
applied per acre per year .  Allow a minimum of 7 days from the last application until cutting or
swathing the crop for harvest .
1Not registered for use in California .

14
4 .50”
4 .0625”
7 .75”
7 .375”
COPY AREA
COPY AREA
APPLICATION DIRECTIONS
CROP DISEASE CONTROLLED
RATE OF PROLINE
480 SC Fungicide
Lentils Ascochyta Blight
  (Ascochyta spp .)
4 .3 - 5 .7 fl oz/A
(0 .134 - 0 .178 lbs ai/A)
PROLINE 480 SC Fungicide may be applied by either ground, aerial or
chemigation application equipment .
Apply PROLINE 480 SC Fungicide at early flower or at the first sign of
disease .  Use the higher use rate when conditions are favorable for severe
disease pressure and/or when growing less disease resistant varieties .
Other Requirements: Apply up to three (3) applications of PROLINE 480 SC Fungicide per
year .  Repeat applications as needed using a 10- to 14-day spray interval if conditions remain
favorable for continued or increasing disease development .  To optimize disease control, the
lowest labeled rate of a spray surfactant should be tank-mixed with PROLINE 480 SC Fungicide .
A maximum of 17 .1 fl oz (0 .534 lbs prothioconazole) of PROLINE 480 SC Fungicide may be
applied per acre per year .  Allow a minimum of 7 days from the last application until cutting or
swathing the crop for harvest .
APPLICATION DIRECTIONS
CROP DISEASE CONTROLLED
RATE OF PROLINE
480 SC Fungicide
Rapeseed
Subgroup 20A
(including canola
and Brassica
carinata1):
Borage, Brassica
carinata, crambe,
cuphea, echium,
flax, gold of
pleasure, hare’s
ear mustard,
lesquerella,
lunaria,
meadowfoam,
milkweek,
mustard seed,
oil radish, poppy
seed, rapeseed,
sesame, sweet
rocket, cultivars,
varieties, and/or
hybrids of these
Sclerotinia Stem Rot
White Mold
  (Sclerotinia sclerotiorum)
4 .3 - 5 .7 fl oz/A
(0 .134 - 0 .178 lbs ai/A)
PROLINE 480 SC Fungicide may be applied by either ground, aerial or
chemigation application equipment . Apply PROLINE 480 SC Fungicide
when the crop is in the 20 - 50% bloom stage  . Best protection will be
achieved when the fungicide is applied prior to petals beginning to fall, and
will allow for the maximum number of petals to be protected . Utilize the
higher rate for fields with a history of heavy disease pressure or for dense
crop stands . Good spray coverage of the plants is essential .
The lowest labelled rate of a non-ionic surfactant may be tank-mixed with
PROLINE 480 SC Fungicide .
Other Requirements: Apply up to two (2) applications of PROLINE 480 SC Fungicide per year .
A second application may be made after 14 days if conditions remain favorable for continued
or increasing disease development . A maximum of 11 .4 fl oz (0 .356 lbs prothioconazole) of
PROLINE 480 SC Fungicide may be applied per acre per year . PROLINE 480 SC Fungicide
may be applied until the 50% bloom stage . Do not apply within 36 days of harvest .
1Not registered for use in California .

15
4 .50”
4 .0625”
7 .75”
7 .375”
COPY AREA
COPY AREA
APPLICATION DIRECTIONS
CROP DISEASE SUPPRESSED
RATE OF PROLINE
480 SC Fungicide
Peanut1

In-furrow and banded
Sclerotium Rot
White Mold
Southern Blight
Southern Stem rot
  (Sclerotium rolfsii)
Rhizoctonia Limb Rot
  (Rhizoctonia solani)
Early Leaf Spot
  (Cercospora arachidicola)
Late Leaf Spot
  (Cercosporidium personatum)
Cylindrocladium Black Rot (CBR)
  (Cylindrocladium crotalariae)
  (Suppression with in furrow only)
0 .4 fl oz per 1000 row feet
(5 .7 fl oz/A)
(0 .178 lbs ai/A)
In-furrow and Banded Spray Program: Apply 5 .7 fl oz per acre (0 .4 fl
oz per 1000 row feet if on 36 inch row spacing) in the furrow at planting .
PROLINE 480 SC Fungicide may also be applied in a 4- to 6- inch band
over the row at or near emergence  . Bayer CropScience recommends a
minimum application volume of 20 gpa .
Other Requirements: Apply up to four (4) applications of PROLINE 480 SC Fungicide
per year, including the in-furrow and banded applications  . A maximum of 22 .8 fl oz (0 .713
lbs prothioconazole) of PROLINE 480 SC Fungicide may be applied per acre per year  .
PROLINE 480 SC Fungicide may be applied up to 14 days before harvest . Do not feed hay
or threshings or allow livestock to graze in treated areas .
1Not registered for use in California .

16
4 .50”
4 .0625”
7 .75”
7 .375”
COPY AREA
COPY AREA
APPLICATION DIRECTIONS
CROP DISEASE CONTROLLED
RATE OF PROLINE
480 SC Fungicide
Soybean Asian Soybean Rust
 (Phakopsora pachyrhizi)
Frog Eye Leaf Spot
 (Cercospora sojina)
Powdery Mildew
 (Microsphaera diffusa)
Brown Spot1
 (Septoria glycines)
2 .5 - 3 .0 fl oz/A
(0 .078 - 0 .094 lbs ai/A)
Alternaria Leaf Spot1
  (Alternaria spp .)
Anthracnose1
  (Colletotrichum truncatum)
Asian Soybean Rust1
  (Phakopsora pachyrhizi)
Brown Spot1
  (Septoria glycines)
Cercospora Blight1
  (Cercospora kikuchii)
Frogeye Leaf Spot1
  (Cercospora sojina)
Pod & Stem Blight1
  (Diaporthe phaseolorum)
Powdery Mildew1
  (Microsphaera diffusa)
Rhizoctonia Aerial Blight1
  (Rhizoctonia solani)
Sclerotinia Stem Rot also known
as White Mold (Sclerotinia
sclerotiorum) (Suppression Only)
3 .0 - 5 .0 fl oz/A
(0 .094 to 0 .156 lbs ai/A)
In Furrow
2 .6 - 5 .0 fl oz/A
(0 .081 - 0 .156 lbs ai/A)Rhizoctonia rots1
 (Rhizoctonia spp .)
PROLINE 480 SC Fungicide may be applied by either ground, aerial
or chemigation application equipment .  For aerial application, apply in
a minimum spray volume of 2 gpa .  Apply PROLINE 480 SC Fungicide
as a broadcast, preventative foliar spray or at first visible symptoms
of the disease  . Repeat applications on a 10- to 21-day spray interval if
environmental conditions are favorable for continued disease development .
Use of the higher rate and shorter spray intervals are recommended when
disease pressure is severe .
In-furrow use: Apply up to 5 .0 fl oz per acre (0 .288 fl oz per 1000 row
feet if on 30 inch row spacing; 0 .192 fl oz per 1000 row feet if on a 20 inch
row spacing) in the furrow at planting .  See use directions and rate chart
for various row spacing under the SOILBORNE/SEEDLING DISEASE
CONTROL section .
Sclerotinia Stem Rot (Suppression Only): Apply PROLINE 480 SC
Fungicide as a broadcast foliar spray at R1 (beginning bloom) when
conditions are favorable for disease development . A sequential treatment
of PROLINE 480 SC Fungicide or Stratego YLD Fungicide may be made
at R3 – R4 (beginning to full pod) .  PROLINE 480 SC Fungicide may be
applied by ground or air . Apply in a minimum of 10 gallons of spray solution
per acre by ground sprayer or in a minimum of 5 gallons of spray solution
per acre by aircraft spray equipment .
Other Requirements: Applications may not be made within 21 days of harvest . Do not apply
more than 3 applications per year including all soil and foliar applications . Do not apply more
than 12 .9 fl oz (0 .403 lbs prothioconazole) of PROLINE 480 SC Fungicide per acre per year .
1Not registered for use in California .

17
4 .50”
4 .0625”
7 .75”
7 .375”
COPY AREA
COPY AREA
APPLICATION DIRECTIONS
CROP DISEASE CONTROLLED
RATE OF PROLINE
480 SC Fungicide
Sugar beets Foliar Diseases
Cercospora Leaf Spot
 (Cercospora beticola)
Powdery Mildew
 (Erysiphe polygoni)
5 .0 - 5 .7 fl oz/A
(0 .156 - 0 .178 lbs ai/A)
In furrow and banded 5 .7 fl oz/A
(0 .178 lbs ai/A)Rhizoctonia Stem Canker, Root
Rot, Crown Rot
 (Rhizoctonia solani)
PROLINE 480 SC Fungicide may be applied by either ground, aerial or
chemigation application equipment .
Foliar disease control: Apply PROLINE 480 SC Fungicide at the first sign
of disease . Use the higher use rate and shorter intervals when conditions
are favorable for severe disease pressure and/or when growing less
disease resistant varieties .
Soil-borne disease control: Apply PROLINE 480 SC Fungicide in a
seven-inch band at the 4-leaf to row closure growth stage .
For in-furrow use: apply up to 5 .7 fl oz per acre (0 .4 fl oz per 1000 row
feet if on 36 inch row spacing) in the furrow at planting . See use directions
and rate chart for various row spacing under the SOILBORNE/SEEDLING
DISEASE CONTROL section .
Other Requirements: Apply up to 3 applications of PROLINE 480 SC Fungicide per year
including all soil and foliar applications . Repeat applications as needed using a 14- to 21-day
spray interval depending on disease pressure . Use a 14-day spray interval under normal to
heavy disease pressure and a 21-day spray interval under light disease pressure .
To optimize disease control, the lowest labeled rate of a spray surfactant may be tank-mixed
with PROLINE 480 SC Fungicide .
A maximum of 17 .1 fl oz of PROLINE 480 SC Fungicide (0 .534 lbs prothioconazole) may
be applied per acre per year  . Allow a minimum of 7 days from the last application before
harvesting .
PROLINE 480 SC Fungicide is a Group 3 fungicide  . To limit the potential  for development
of disease resistance:
  • Alternate every application of PROLINE 480 SC Fungicide with a non-Group 3 fungicide .

18
4 .50”
4 .0625”
7 .75”
7 .375”
COPY AREA
COPY AREA
APPLICATION DIRECTIONS
CROP DISEASE CONTROLLED
RATE OF PROLINE
480 SC Fungicide
Wheat (spring,
  durum and
  winter)
Triticale
Fusarium Head Blight (Fusarium spp .)
 (Suppression Only)
5 .0 - 5 .7 fl oz/A
(0 .156 - 0 .178 lbs ai/A)
Leaf and Stem Diseases
Powdery Mildew (Blumeria graminis f .
sp . tritici)
Rusts (Puccinia spp .)
Septoria Leaf and Glume Blotch
(Septoria tritici)
Stagonospora Blotch (Stagonospora
nodorum)
Tan Spot (Pyrenophora tritici-repentis)
4 .3 - 5 .0 fl oz/A
(0 .134 - 0 .156 lbs ai/A)
PROLINE 480 SC Fungicide may be applied by either ground, aerial or
chemigation application equipment .
For aerial application made prior to early flower (prior to Feekes Growth
Stage 10 .51, apply a minimum of 2 gpa spray solution .  For aerial
applications made at the early flower growth stage or later, apply in a
minimum of 5 gpa spray solution .  Chemigation use is allowed only for
applications made prior to early flower  .
Fusarium Head Blight (Suppression Only): The optimal time to apply
PROLINE 480 SC Fungicide is as a preventative foliar spray at early
flower (Feekes Growth Stage 10 .51) .  Spray equipment must be set to
provide good coverage to wheat heads  . For thorough coverage of the
wheat head using ground application equipment, use forward and
backward mounted nozzles or nozzles that have a two-directional spray  .
Operate nozzles within the spray pressure directions suggested by the
manufacturer .
Leaf and Stem Diseases: Apply PROLINE 480 SC Fungicide as a
preventive foliar spray when the earliest disease symptoms appear on
the leaves or stems  . Wheat fields should be observed closely for early
disease symptoms, particularly when susceptible varieties are planted
and/or under prolonged conditions favorable for disease development .
Other Requirements: Apply up to two (2) applications of PROLINE 480 SC Fungicide per
year . Repeat applications using a 14-day spray interval if conditions remain favorable for
continued or increasing disease development .   For optimum disease control, the lowest
labeled rate of a spray surfactant should be tank mixed with PROLINE 480 SC Fungicide .
A maximum of 9 .37 fl oz (0 .293 lbs prothioconazole) of PROLINE 480 SC Fungicide may be
applied per acre per year . Do not apply within 30 days of harvest .

19
4 .50”
4 .0625”
7 .75”
7 .375”
COPY AREA
COPY AREA
APPLICATION DIRECTIONS
CROP DISEASE CONTROLLED
RATE OF PROLINE
480 SC FUNGICIDE
Nursery seedlings
of Shortleaf, Loblolly,
Slash, Longleaf and
other pines and
other Conifers and
Hardwoods
Fusiform rust
 (Cronartium quercum f.sp .
 fusiforme)
Pitch canker
 (Fusarium spp .)
Rhizoctonia foliar blight
 (Rhizoctonia spp .)
5 .0 fl oz/A
(0 .156 lbs ai/A)
Nursery seeds of
Shortleaf, Loblolly,
Slash, Longleaf and
other pines and
other Conifers and
Hardwoods
Fusiform rust
 (Cronartium quercum f .sp .
 fusiforme)
Pitch canker
 (Fusarium spp .)
10 fl oz per 50 lbs seed
Do not use in forest planting or established woodlands.
The crop safety and mix compatibility on all tree species and in tank-mixes with other
products (spray surfactants, fertilizers, insecticides, etc .) has not been confirmed .  Bayer
CropScience recommends small scale testing with your planned use pattern .  The user
assumes all risks with the use of this product on trees .
Tree Seedling Application Directions: Foliar disease control: Apply PROLINE 480 SC
Fungicide preventatively or at the first sign of disease using ground equipment only . Repeat
applications as needed using a 14- to 21-day spray interval depending on your region .
Consult your local extension agent on locally recommended spray intervals  . Use shorter
intervals when conditions are favorable for severe disease pressure and/or when growing
less disease resistant varieties  . To optimize disease control, the lowest labeled rate of  a
spray surfactant may be tank-mixed with PROLINE 480 SC Fungicide  . A maximum of
25 fl oz (0 .781 lbs prothioconazole) of PROLINE 480 SC Fungicide may be applied per
acre per crop year .
Tree Seed Treatment Directions: Apply specified dosage to seed in a commercial treater
or other suitable tumbler apparatus  . Allow to mix for at least 10 minutes  . Thoroughly air
dry before sowing . Do not use treated seed for food or feed purposes  . Seed that has been
treated with this product that is then packaged or bagged for future use must contain the
following labeling on the outside of the seed package or bag:  “This seed has been treated
with prothioconazole . Treated Seed – Do not Use for Food, Feed, or Oil Purposes  . When
opening this bag or loading/pouring the treated seed, wear a long sleeved shirt, long pants,
shoes, socks, and chemical resistant gloves . After the seeds have been planted, do not enter
or allow worker entry into treated areas during the restricted-entry interval (REI) of 12 hours .
Exception: Once the seeds are planted in soil or other planting media, the Worker Protection
Standard allows workers to enter the treated area without restriction if there will be no worker
contact with the treated seeds in the soil or planting media .”

STORAGE AND DISPOSAL
Do not contaminate water, food, or feed by storage or disposal .
Pesticide Storage: Store in a cool, dry place and in such a manner as to prevent
cross contamination with other pesticides, fertilizers, food, and feed .  Store in original
container and out of the reach of children, preferably in a locked storage area .
Handle and open container in a manner as to prevent spillage  . If container is
leaking, invert to prevent leakage . If the container is leaking or material is spilled
for any reason or cause, carefully dam up spilled material to prevent runoff . Refer
to Precautionary Statements on label for hazards associated with the handling
of this material . Do not walk through spilled material . Absorb spilled material with
absorbing type compounds and dispose of as directed for pesticides on next page .
In spill or leak incidents, keep unauthorized people away  . Y ou may contact the
Bayer CropScience Emergency Response Team for decontamination procedures
or any other assistance that may be necessary . The Bayer CropScience Emergency
Response Telephone No . is 1-800-334-7577 . (continued)

20
4 .50”
4 .0625”
7 .75”
7 .375”
COPY AREA
COPY AREA
Pesticide Disposal:  Wastes resulting from the use of this product must be disposed
of on-site or at an approved waste disposal facility .
Container Disposal:  Non-refillable container . Do not reuse or refill this container .
Triple rinse or pressure rinse container (or equivalent) promptly after emptying .
Triple rinse as follows: Empty the remaining contents into application equipment or
a mix tank and drain for 10 seconds after the flow begins to drip . Fill the container
1/4 full with water and recap  . Shake for 10 seconds . Pour rinsate into application
equipment or a mix tank or store rinsate for later use or disposal .  Drain for 10
seconds after the flow begins to drip . Repeat this procedure two more times .
Pressure rinse as follows: Empty the remaining contents into application equipment
or a mix tank and continue to drain for 10 seconds after the flow begins to drip . Hold
container upside down over application equipment or mix tank or collect rinsate for
later use or disposal . Insert pressure-rinsing nozzle in the side of the container, and
rinse at about 40 PSI for at least 30 seconds  . Drain for 10 seconds after the flow
begins to drip .
Offer for recycling, if available . If not recycled, then puncture and dispose of in a
sanitary landfill, or by incineration, or, if allowed by state and local authorities, by
burning . If burned, stay out of smoke .
IMPORTANT: READ BEFORE USE
Read the entire Directions for Use, Conditions, Disclaimer of Warranties and
Limitations of Liability before using this product .  If terms are not acceptable, return
the unopened product container at once .
By using this product, user or buyer accepts the following Conditions, Disclaimer of
Warranties and Limitations of Liability .
CONDITIONS: The directions for use of this product are believed to be adequate and
must be followed carefully . However, it is impossible to eliminate all risks associated
with the use of this product .   Crop injury, ineffectiveness or other unintended
consequences may result because of such factors as weather conditions, presence
of other materials, or the manner of use or application, all of which are beyond the
control of Bayer CropScience .  To the extent consistent with applicable law, all such
risks shall be assumed by the user or buyer .
DISCLAIMER OF WARRANTIES: TO THE EXTENT CONSISTENT WITH
APPLICABLE LAW, BAYER CROPSCIENCE MAKES NO OTHER WARRANTIES,
EXPRESS OR IMPLIED, OF MERCHANTABILITY OR OF FITNESS FOR A
PARTICULAR PURPOSE OR OTHERWISE, THAT EXTEND BEYOND THE
STATEMENTS MADE ON THIS LABEL .  No agent of Bayer CropScience is
authorized to make any warranties beyond those contained herein or to modify the
warranties contained herein . TO THE EXTENT CONSISTENT WITH APPLICABLE
LAW, BAYER CROPSCIENCE DISCLAIMS ANY LIABILITY WHATSOEVER FOR
SPECIAL, INCIDENTAL OR CONSEQUENTIAL DAMAGES RESULTING FROM
THE USE OR HANDLING OF THIS PRODUCT .
LIMITATIONS OF LIABILITY: TO THE EXTENT CONSISTENT WITH APPLICABLE
LAW, THE EXCLUSIVE REMEDY OF THE USER OR BUYER FOR ANY AND
ALL LOSSES, INJURIES OR DAMAGES RESULTING FROM THE USE OR
HANDLING OF THIS PRODUCT, WHETHER IN CONTRACT, WARRANTY , TORT,
NEGLIGENCE, STRICT LIABILITY OR OTHERWISE, SHALL NOT EXCEED THE
PURCHASE PRICE PAID, OR AT BAYER CROPSCIENCE’S ELECTION, THE
REPLACEMENT OF PRODUCT .

21
4 .50”
4 .0625”
7 .75”
7 .375”
COPY AREA
COPY AREA

22
4 .50”
4 .0625”
7 .75”
7 .375”
COPY AREA
COPY AREA

23
4 .50”
4 .0625”
7 .75”
7 .375”
COPY AREA
COPY AREA

PLACE BAR CODE HERE
5.50”
BASE LABEL
4.125”0.875” 0.50”
7.75”
7.50”
COPY AREA
COPY AREA
NET CONTENTS: 2 1/2 GALLONS
PROTHIOCONAZOLEGROUP 3 FUNGICIDE
(01)  0 0785740 11651  7
STORAGE AND DISPOSAL
Do not contaminate water, food, or feed by storage
or disposal .
Pesticide Storage: Store in a cool, dry place and
in such a manner as to prevent cross contamination
with other pesticides, fertilizers, food, and feed .
Store in original container and out of the reach of
children, preferably in a locked storage area .
Handle and open container in a manner as to prevent
spillage . If container is leaking, invert to prevent
leakage . If the container is leaking or material is spilled
for any reason or cause, carefully dam up spilled
material to prevent runoff  . Refer to Precautionary
Statements on label for hazards associated with the
handling of this material . Do not walk through spilled
material . Absorb spilled material with absorbing type
compounds and dispose of as directed for pesticides
below . In spill or leak incidents, keep unauthorized
people away . Y ou may contact the Bayer CropScience
Emergency Response Team for decontamination
procedures or any other assistance that may be
necessary . The Bayer CropScience Emergency
Response Telephone No . is 1-800-334-7577 .
Pesticide Disposal: Wastes resulting from the use
of this product must be disposed of on-site or at an
approved waste disposal facility .
Container Disposal: Non-refillable container  .
Do not reuse or refill this container  . Triple rinse or
pressure rinse container (or equivalent) promptly
after emptying .
Triple rinse as follows: Empty the remaining contents
into application equipment or a mix tank and drain
for 10 seconds after the flow begins to drip  . Fill the
container 1/4 full with water and recap . Shake for 10
seconds . Pour rinsate into application equipment or
a mix tank or store rinsate for later use or disposal .
Drain for 10 seconds after the flow begins to drip  .
Repeat this procedure two more times .
Pressure rinse as follows: Empty the remaining
contents into application equipment or a mix tank
and continue to drain for 10 seconds after the flow
begins to drip  . Hold container upside down over
application equipment or mix tank or collect rinsate
for later use or disposal .  Insert pressure-rinsing
nozzle in the side of the container, and rinse at about
40 PSI for at least 30 seconds . Drain for 10 seconds
after the flow begins to drip .
Offer for recycling, if available  . If not recycled, then
puncture and dispose of in a sanitary landfill, or
by incineration, or, if allowed by state and local
authorities, by burning . If burned, stay out of smoke .
Bayer CropScience LP
800 N . Lindbergh Blvd .
St . Louis, MO 63167
PROLINE is a registered trademark of Bayer .
©2019 Bayer CropScience
US61380068C             190322C  05/19
FIRST AID
IF
SWALLOWED:
• Immediately call a poison
control center or doctor for
treatment advice .
• Have person sip a glass of
water if able to swallow .
• Do not induce vomiting unless
told to do so by a poison
control center or doctor .
• Do not give anything by mouth
to an unconscious person .
IF INHALED: • Move person to fresh air .
• If person is not breathing, call
911 or an ambulance, then
give artificial respiration,
preferably mouth-to-mouth if
possible .
• Call a poison control center
or doctor for further treatment
advice .
IF ON SKIN
OR
CLOTHING:
• Take off contaminated
clothing .
• Rinse skin immediately with
plenty of water for 15-20
minutes .
• Call a poison control center or
doctor for treatment advice .
IF IN EYES:

• Hold eye open and rinse
slowly and gently with water
for 15-20 minutes .
• Remove contact lenses, if
present, after the first 5
minutes, then continue rinsing
eye .
• Call a poison control center or
doctor for treatment advice .
For MEDICAL Emergencies Call 24 Hours
A Day 1-800-334-7577.
Have the product container or label with
you when calling a poison control center or
doctor or going for treatment.
NOTE TO PHYSICIAN: No specific antidote . Treat
symptomatically .
PRECAUTIONARY STATEMENTS
HAZARD (TO HUMANS AND DOMESTIC ANIMALS)
CAUTION
Harmful if swallowed or inhaled . Causes moderate
eye irritation . Avoid contact with eyes and clothing .
Avoid breathing vapor or spray mist . Wash thoroughly
with soap and water after handling and before eating,
drinking, chewing gum, or using tobacco  . Remove
and wash contaminated clothing before reuse .
PROLINE® 480 SC Fungicide
For control of specified diseases on listed crops.
ACTIVE INGREDIENT: Prothioconazole, 2-[2-(1-Chlorocyclopropyl)-3-
 (2-chlorophenyl)-2-hydroxypropyl]-1,2-dihydro-3H-1,2,4-triazole-3-thione  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  41.0%
OTHER INGREDIENTS:  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  59.0%
Contains 4 pounds Prothioconazole per gallon                                                     TOTAL:  100.0%
EPA Reg. No. 264-825
KEEP OUT OF REACH OF CHILDREN
CAUTION
For MEDICAL And TRANSPORTATION Emergencies ONLY Call 24 Hours A Day 1-800-334-7577
For PRODUCT USE Information Call 1-866-99BAYER (1-866-992-2937)
Please refer to booklet for additional precautionary statements and directions for use.