crop-chem-docs/corpus/epa_ppls/100-1226.md

# Alto® 100SL Fungicide

- EPA Reg No: **100-1226**
- Registrant: SYNGENTA CROP PROTECTION, LLC
- Signal word: Caution
- Active ingredients: Cyproconazole (8.9%)
- Label accepted: 2024-05-24
- Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000100-01226-20240524.pdf

---
May 24, 2024
Rebecca Haynie
Regulatory Product Manager
Syngenta Crop Protection, Inc.
P. O. Box 18300
Greensboro, NC 27419
Subject: Label Amendment - Registratio n Review Mitigation for Cyproconazole
Product Name: ALTO 100 SL FUNGICIDE
EPA Registration Number: 100-1226
Application Date: 12/18/2020
Decision Number: 568968
Dear Rebecca Haynie:
The Agency, in accordance with the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), 
as amended, has completed reviewing all the information submitted with your application to 
support the Registration Review of the above referenced product in connection with the 
Cyproconazole Interim Decision and has concluded that your submission is acceptable. The 
label referred to above, submitted in connection with registration under FIFRA, as amended, is 
acceptable.
Should you wish to add/retain a reference to the company’s website on your label, then please 
be aware that the website becomes labeling under the Federal Insecticide, Fungicide, and 
Rodenticide Act and is subject to review by the Agency. If the website is false or misleading, the 
product would be misbranded and unlawful to sell or distribute under FIFRA section 12(a)(1)(E). 
40 CFR 156.10(a)(5) list examples of statements EPA may consider false or misleading. In 
addition, regardless of whether a website is referenced on your product’s label, claims made on 
the website may not substantially differ from those claims approved through the registration 
process. Therefore, should the Agency find or if it is brought to our attention that a website 
contains false or misleading statements or claims substantially differing from the EPA approved 
registration, the website will be referred to the EPA’s Office of Enforcement and Compliance
Assurance.
A stamped copy of your labeling is enclosed for your records. This labeling supersedes 
all previously accepted labeling and must be used at your next label printing. You must

Page 2 of 2 
EPA Reg. No. 100-1226 
Decision No. 568968 
 
submit one copy of the final printed labeling before you release the product for 
shipment with the new labeling. In accordance with 40 CFR 152.130(c), you may 
distribute or sell this product under the previously approved labeling for 12 months 
from the date of this letter. After 12 months, you may only distribute or sell this 
product if it bears this new revised labeling or subsequently approved labeling. “To 
distribute or sell” is defined under FIFRA section 2(gg) and its implementing regulation 
at 40 CFR 152.3. 
 
If you have any questions about this letter, please contact Carolyn Smith by phone at 202-566-
2273, or via email at smith.carolyn@epa.gov. 
 
 
 S i n c e r e l y , 
 
 
 
 
Jaclyn Pyne, Team Leader 
 Risk Management and Implementation Branch 3 
 Pesticide Re-Evaluation Division 
 Office of Pesticide Programs
 
 
ENCLOSURE: Stamped label

Master Label
Alto® 100SL Fungicide
Broad spectrum fungicide for control of the listed plant diseases
Active Ingredient:
Cyproconazole*..........................................................................................8.9%
Other Ingredients: 91.1%
Total: 100.0%
*CAS No. 94361-06-5
Alto 100SL Fungicide is a soluble concentrate formulation which contains 0.83 lb ai
cyproconazole per gallon.
KEEP OUT OF REACH OF CHILDREN.
CAUTION
See additional precautionary statements and directions for use inside booklet.
EPA Reg. No. 100-1226
EPA Est. No.
______ gallons
Net Contents
CYPROCONAZOLE GROUP 3 FUNGICIDE
05/24/2024
100-1226

Master Label 
TABLE OF CONTENTS 
 
1.0 FIRST AID 
2.0 PRECAUTIONARY STATEMENTS 
2.1 Hazards to Humans and Domestic Animals 
2.2 Personal Protective Equipment (PPE) 
 2.2.1 USER SAFETY REQUIREMENTS 
 2.2.2 ENGINEERING CONTROL STATEMENTS 
2.3 Environmental Hazards 
 2.3.1 GROUND WATER ADVISORY 
 
DIRECTIONS FOR USE 
 
3.0 PRODUCT INFORMATION
 
3.1 Integrated Pest (Disease) Management 
3.2 Resistance Management 
4.0 APPLICATION DIRECTIONS 
4.1 Methods of Application 
4.2 Application Equipment 
 4.2.1 NOZZLES 
 4.2.2 PUMP 
4.3 Application Volume and Spray Coverage
 
4.4 Mixing Directions 
 4.4.1 ALTO 100SL FUNGICIDE ALONE 
 4.4.2 TANK-MIX PRECAUTIONS 
 4.4.3 TANK-MIX RESTRICTIONS 
 4.4.4 TANK-MIX COMPATIBILITY 
 4.4.5 ALTO 100SL FUNGICIDE IN TANK MIXTURES 
 4.4.6 SPRAY ADDITIVES 
4.5 Application through Irrigation Systems (Chemigation) 
 4.5.1 CHEMIGATION RESTRICTIONS 
 4.5.2 OPERATING INST RUCTIONS FOR CHEMIGATION 
 4.5.3 SPECIFIC INSTRUCTIONS FOR PUBLIC WATER SYSTEMS 
 4.5.4 APPLICATION DIRECTIONS FOR SPRINKLER IRRIGATION SYSTEMS 
5.0 ROTATIONAL CROP RESTRICTIONS
 
6.0 RESTRICTIONS AND PRECAUTIONS 
6.1 Use Restrictions 
6.2 Use Precautions 
6.3 Spray Drift Advisories 
 6.3.1 IMPORTANCE OF DROPLET SIZE 
 6.3.2 CONTROLLING DROPLET SIZE – GROUND BOOM 
 6.3.3 CONTROLLING DROPLET SIZE – AIRCRAFT 
 6.3.4 BOOM HEIGHT – GROUNDBOOM 
 6.3.5 RELEASE HEIGHT – AIRCRAFT 
 6.3.6 SHIELDED SPRAYERS 
 6.3.7 TEMPERATURE AND HUMIDITY

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 6.3.8 TEMPERATURE INVERSIONS 
 6.3.9 WIND 
7.0 CROP USE DIRECTIONS
 
7.1 Cereals 
7.2 Corn 
7.3 Peanut 
7.4 Soybean 
8.0 STORAGE AND DISPOSAL 
9.0 CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY 
10.0 [OPTIONAL TABLE:] USE SUMMARY TABLE

Master Label 
1.0 FIRST AID 
FIRST AID 
If swallowed x Call a poison control center or doc tor immediately for treatment 
advice. 
x Have person sip a glass of water if able to swallow. 
x Do not induce vomiting unless told to do so by a poison control 
center or doctor. 
x Do not give anything by mouth to an unconscious person. 
If on skin or 
clothing 
x Take off contaminated clothing. 
x Rinse skin immediately with plenty of water for 15-20 minutes. 
x Call a poison control center or doctor for treatment advice. 
If in eyes x Hold eye open and rinse slowly and gently with water for 15-20 
minutes. 
x Remove contact lenses, if present, after the first 5 minutes, then 
continue rinsing eye. 
x Call a poison control center or doctor for treatment advice. 
If inhaled x Move person to fresh air. 
x If person is not breathing, call 911 or an ambulance, then give 
artificial respiration, preferably by mouth-to-mouth, if possible. 
x Call a poison control center or doctor for treatment advice. 
Have the product container or label with y ou when calling a poison control center or 
doctor, or going for treatment. 
SYNGENTA HOTLINE NUMBER 
For 24-Hour Medical Emergency Assistance (Human or Animal) or 
Chemical Emergency Assistance (Spill, Leak, Fire, or Accident), 
Call 
1-800-888-8372 
 
2.0 PRECAUTIONARY STATEMENTS 
2.1 Hazards to Humans and Domestic Animals 
CAUTION 
Harmful if swallowed, inhaled, or absorbed through skin. Avoid contact with skin, eyes, 
or clothing. Causes moderate eye irritation. Wash thoroughly with soap and water after 
handling and before eating, drinking, chewing gum, using tobacco, or using the toilet. 
Remove and wash contaminated clothing before reuse. 
 
2.2 Personal Protective Equipment (PPE) 
 
Applicators and other handlers must wear: 
x Long-sleeved shirt and long pants 
x Chemical-resistant gloves made of barrier laminate or butyl rubber ≥ 14 mils 
x Shoes plus socks

Alto 100SL 
Page 5 
 
2.2.1 USER SAFETY REQUIREMENTS 
Follow the manufacturer’s instructions for cleaning/maintaining PPE. If no such 
instructions for washables exist, use detergent and hot water. Keep and wash PPE 
separately from other laundry. 
 
2.2.2 ENGINEERING CONTROL STATEMENTS 
When handlers use closed systems, enclosed cabs, or aircraft in a manner that meets 
the requirements listed in the Worker Protection Standard (WPS) for agricultural 
pesticides (40 CFR 170.240(d)(4-6)), the handler PPE requirements may be reduced or 
modified as specified in the WPS. 
 
USER SAFETY RECOMMENDATIONS 
Users should: 
x Wash hands before eating, drinking, chewing gum, using tobacco, or using the 
toilet. 
x Remove clothing/PPE immediately if pesticide gets inside. Then wash thoroughly 
and put on clean clothing. 
x Remove PPE immediately after handling this product. Wash the outside of gloves 
before removing. As soon as possible, wash thoroughly and change into clean 
clothing. 
 
2.3 Environmental Hazards 
For terrestrial uses: Do not apply directly to water, to areas where surface water is 
present, or to intertidal areas below the mean high-water mark. Do not contaminate 
water when disposing of equipment washwater or rinsate. 
 
2.3.1 GROUND WATER ADVISORY 
This chemical has properties and characteristics associated with chemicals detected in 
ground water. This chemical may leach into ground water if used in areas where soils 
are permeable, particularly where the water table is shallow. 
 
Notify state and/or federal authorities and Syngenta immediately if you observe any 
adverse environmental effects due to use of this product.

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DIRECTIONS FOR USE 
 
It is a violation of federal law to use this product in a manner inconsistent with its 
labeling. 
 
Alto 100SL Fungicide must be used only in accordance with directions on this label or in 
separately published EPA approved supplemental labeling for this product. 
 
FAILURE TO FOLLOW THE USE DIRECTIONS AND PRECAUTIONS ON THIS 
LABEL MAY RESULT IN PLANT INJURY, POOR DISEASE CONTROL, AND/OR 
ILLEGAL RESIDUES. 
 
Do not apply this product in a way that will contact workers or other persons, either 
directly or through drift. Only protected handlers may be in the area during application. 
For any requirements specific to your state or tribe, consult the agency responsible for 
pesticide regulation. 
 
 
AGRICULTURAL USE REQUIREMENTS 
Use this product only in accordance with its labeling and with the Worker Protection 
Standard, 40 CFR Part 170. This Standard contains requirements for the protection 
of agricultural workers on farms and forests, and handlers of agricultural pesticides. 
It contains requirements for training, decontamination, notification, and emergency 
assistance. It also contains specific instructions and exceptions pertaining to the 
statements on this label about personal protective equipment (PPE), notification to 
workers, and restricted-entry interval. The requirements in this box only apply to 
uses of this product that are covered by the Worker Protection Standard. 
 
Do not enter or allow worker entry into treated areas during the restricted entry 
interval (REI) of 12 hours. 
 
PPE required for early entry to treated areas that is permitted under the Worker 
Protection Standard and that involves contact with anything that has been treated, 
such as plants, soil, or water is: 
x Coveralls 
x Chemical-resistant gloves made of barrier laminate or butyl rubber ≥ 14 mils 
x Shoes plus socks

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3.0 PRODUCT INFORMATION 
Alto 100SL Fungicide is a broad-spectrum fungicide for control of certain diseases in 
soybeans, corn, peanuts, and wheat. All applications must be made according to the 
use directions that follow. 
 
3.1 Integrated Pest (Disease) Management 
Alto 100SL Fungicide should be integrated into an overall disease and pest 
management strategy whenever the use of a fungicide is required. Cultural practices 
known to reduce disease development should be followed. See Section 7.0 for crop-
specific IPM recommendations. Consult your local agricultural authorities for additional 
IPM strategies established for your area. Alto 100SL Fungicide may be used in state 
agricultural extension advisory (disease forecasting) programs which recommend 
application timing based on environmental factors favorable for disease development. 
 
3.2 Resistance 
Management 
 
 
For resistance management, Alto 100SL Fungicide contains a Group 3 fungicide. Any 
fungal population may contain individuals naturally resistant to Alto 100SL Fungicide 
and other Group 3 fungicides. A gradual or total loss of pest control may occur over time 
if these fungicides are used repeatedly in the same fields. Appropriate resistance-
management strategies should be followed. 
 
Alto 100SL Fungicide should not be alternated or tank mixed with any fungicide to which 
resistance has developed for the disease to be controlled. 
 
To delay fungicide resistance, take one or more of the following steps: 
 
 
x Rotate the use of Alto 100SL Fungicide or other Group 3 fungicides within a growing 
season sequence with different groups that control the same pathogens. 
x Use tank mixtures with fung icides from a different group that are equally effective on 
the target pest when such use is permitted. Use at least the minimum application rate 
as labeled by the manufacturer. 
x Adopt an integrated disease management program for fungicide use that includes 
scouting, uses historical information related to pesticide use, and crop rotation, and 
which considers host plant resistance, impact of environmental conditions on disease 
development, disease thresholds, as well as cultural, biological, and other chemical 
control practices. 
x Where possible, make use of predictive di sease models to effectively time fungicide 
applications. Note that using predictive models alone is not sufficient to manage 
resistance. 
x Monitor treated fungal populations for resistance development. 
CYPROCONAZOLE GROUP 3 FUNGICIDE

Alto 100SL 
Page 8 
x Contact your local extension specialist or certified crop advisor for any additional 
pesticide resistance-management and/or IPM recommendations for specific crops 
and pathogens. 
x For further information or to report suspected resistance, contact Syngenta Crop 
Protection at 1-866-796-4368. You can also contact your pesticide distributor or 
university extension specialist to report resistance. 
 
4.0 APPLICATION DIRECTIONS 
4.1 Methods of Application 
Alto 100SL Fungicide may be applied by ground, by air, or chemigation depending on 
the crop. Refer to Section 7.0 for crop-specific instructions. 
 
4.2 Application Equipment 
Alto 100SL Fungicide may be applied with all types of spray equipment commonly used 
for making ground and aerial applications. Do not apply Alto 100SL Fungicide through 
any type of ultra-low volume (ULV) spray system. Proper adjustments and calibration of 
spraying equipment to give good canopy penetration and coverage is essential for good 
disease control. 
 
4.2.1 NOZZLES 
x Equip sprayers with nozzles that provide accurate and uniform application. 
x Be certain that nozzles are the same size and uniformly spaced across the boom. 
x Calibrate sprayer before use. 
x Although Alto 100SL Fungicide is a soluble concentrate, it is suggested that screens 
be used to protect the pump and to prevent nozzles from clogging. 
x Screens placed on suction side of pump should be 16-mesh or coarser. 
x Do not place a screen in the recirculation line. 
x Use 50-mesh or coarser screens between the pump and boom, and where required 
at the nozzles. 
x Check nozzle manufacturer’s recommendations. 
 
4.2.2 PUMP 
x Use a pump with capacity to: 
o Maintain at least 35 - 40 psi at nozzles. 
o Provide sufficient agitation in tank to keep mixture in suspension (this requires 
recirculation of 10% of tank volume per minute). 
x Use a jet agitator or liquid sparge tube for agitation. 
x Do not air sparge. 
 
For more information on spray equipment and calibration, consult sprayer 
manufacturers and state recommendations. For specific local directions and spray 
schedules, consult the current state and local agricultural recommendations.

Alto 100SL 
Page 9 
4.3 Application Volume and Spray Coverage 
 Apply Alto 100SL Fungicide in a minimum spray volume of 10 gallons per acre for 
ground application, and 2 gallons per acre for aerial application. Use sufficient water for 
adequate coverage and canopy penetration. 
 
4.4 Mixing Directions 
1. Thoroughly clean spray equipment before using this product. 
2. Prepare no more spray mixture than is required for the immediate operation. 
3. Keep product container tightly closed when not in use. 
4. Agitate the spray solution before and during application. 
5. Do not let the spray mixture stand overnight in the spray tank. 
6. Rinse spray tank thoroughly with clean water after each day’s use and dispose of 
pesticide rinsate by application to an already treated area. 
 
4.4.1 ALTO 100SL FUNGICIDE ALONE 
1. Add 1/2 to 2/3 of the required amount of water to the spray or mixing tank. 
2. With the agitator running, add the Alto 100SL Fungicide to the tank. 
3. Continue agitation while adding the remainder of the water. 
4. Begin application of the spray solution after the Alto 100SL Fungicide has completely 
dispersed into the mix water. 
5. Maintain agitation until all of the mixture has been sprayed. 
 
4.4.2 TANK-MIX PRECAUTIONS 
x If using Alto 100SL Fungicide in a tank mixture, observe all directions for use, 
crops/sites, use rates, dilution ratios, precautions, and limitations which appear on the 
tank-mix product(s) label(s). 
x Tank mixtures or other applications of pr oducts referenced on this label are permitted 
only in those states in which the referenced products are registered. 
x The safety of all potential tank mixes on all crops may not have been tested. Before 
applying any tank mixture not specifically recommended on this label, the safety of 
the target crop should be confirmed. 
 
4.4.3 TANK-MIX RESTRICTIONS 
x Do not exceed any label dosage rates. Follow the most restrictive label precautions 
and limitations of any tank-mix partners. 
x Do not mix this product with any pr oduct which prohibits such mixing. 
 
4.4.4 TANK-MIX COMPATIBILITY 
Alto 100SL Fungicide is usually compatible with all tank-mix partners listed on this label. 
However, before tank mixing, use a jar test, as described below, to determine the 
physical compatibility of tank-mix partners. 
 
Compatibility Test: Always check tank-mix compatibility with tank-mixed partners 
each time before use. Commercial application equipment may improve tank-mix 
compatibility in some instances.

Alto 100SL 
Page 10 
 
The following test assumes a spray volume of 25 gal/A. For other spray volumes, make 
appropriate changes in the components. Check tank-mix compatibility using this 
procedure: 
1. Add 1 pint of carrier (either the water or liquid fertilizer to be used in the spray 
operation) to each of two clear 1-quart jars with tight lids. 
 
2. To one of the jars, add ¼ teaspoon or 1.2 milliliters of a commercially available tank-
mix compatibility agent approved for this use (¼ teaspoon is equivalent to 2 pints per 
100 gallons spray). Invert the jar, then shake or stir gently to ensure thorough 
mixing. 
 
3. To both jars, add the appropriate amount of each tank-mix partner. If more than one 
tank-mix partner is to be used, add them separately and adhere to this mixing order: 
dry formulations (wettable powders or water dispersible granules) first, followed by 
liquid flowables, capsule suspensions, emulsifiable concentrates and finally 
adjuvants. After each addition, invert the jar, then shake or stir gently to thoroughly 
mix. The appropriate amount of each tank-mix partner for this test is as follows: 
 
Dry formulations: Add the tank-mix ingredients in their relative proportions; e.g., for 
each pound to be applied per acre, add 1.5 level tsp to each jar. 
 
Liquid formulations: Add the tank-mix ingredients in their relative proportions; e.g., for 
each pint to be applied per acre, add 0.5 tsp or 2.5 mL to each jar. 
 
4. After adding all ingredients, put lids on and tighten, then invert each jar 10 times to 
fully mix. Let the mixtures stand for 15-30 minutes and then assess by looking for 
separation, large flakes, precipitates, gels, heavy oily film on the jar, or other signs of 
incompatibility. Determine if a compatibility agent is needed in the spray mixture by 
comparing the two jars. If either mixture separates, but can be remixed readily, the 
mixture can be sprayed as long as good agitation is used. If the mixtures are 
incompatible, test the following methods of improving compatibility: (A) slurry dry 
formulations in water before addition, or (B) add the compatibility agent directly into 
liquid formulations before addition to the tank mixture. If these procedures are 
followed but incompatibility is still observed, do not use the tank mixture. 
 
4.4.5 ALTO 100SL FUNGICIDE IN TANK MIXTURES 
1. Add 1/2 to 2/3 of the required amount of water to the spray or mixing tank. 
2. With the agitator running, add the tank-mix partner(s) into the tank. 
3. In general, add tank-mix partner(s) in this order: 
a. products packaged in water-soluble packaging 
b. wettable powders 
c. wettable granules (dry flowables) 
d. liquid flowables 
e. liquids 
f. emulsifiable concentrates

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Page 11 
4. Allow each product to completely dissolv e and disperse into the mix water before 
adding the next one. 
5. Continue agitation while adding the remainder of the water, additive as needed, and 
the Alto 100SL Fungicide to the spray tank. 
6. Allow the Alto 100SL Fungicide to completely disperse. 
7. Spray the mixture with the agitator running. 
 
4.4.6 SPRAY ADDITIVES 
x When an adjuvant is to be used with this product, use one that meets the standards 
of the Council of Producers & Distributors of Agrotechnology (CPDA) adjuvant 
certification is recommended. 
x Refer to individual crop use directions in Section 7.0 for use of additives. 
 
4.5 Application through Irrigation Systems (Chemigation) 
x If you have questions about calibration, contact state extension service specialists, 
equipment manufacturers, or other experts. 
4.5.1 CHEMIGATION RESTRICTIONS 
x A pply Alto 100SL Fungicide only to crops for which chemigation is specified on this 
label. 
x Do not apply this product through any other type of irrigation system except as 
specified on this label. 
x Do not apply when winds are greater than 10-15 mph to avoid drift or wind skips. 
x Do not apply when wind speed favors drift beyond the area intended for treatment. 
Plant injury, lack of effectiveness, or illegal pesticide residues in the crop can result 
from non-uniform treated water. 
x Do not inject Alto 100SL Fungicide at full st rength or deterioration of valves and seals 
may occur. Use a dilution ratio of at least 10 parts water to 1 part Alto 100SL 
Fungicide. Alto 100SL Fungicide is corrosive to many seal materials. Leather seals 
are best; EPDM or silicone rubber seals can be used, but should be replaced once a 
year. Do not use Viton™, Buna-N, Neoprene, or PVC seals. 
x Allow sufficient time for the pesticide to be flushed through all lines and all nozzles 
before turning off irrigation water. 
x A person knowledgeable of the chemigation system and responsible for its operation, 
or under the supervision of the responsible person, shall shut the system down and 
make necessary adjustments should the need arise. 
x Do not connect an irrigation system used for pesticide application to a public water 
system unless the pesticide label-prescribed safety devices for public water systems 
are in place. 
 
4.5.2 OPERATING INSTRUCTIONS FOR CHEMIGATION 
1. The system must contain a functional check valve, vacuum relief valve, and low 
pressure drain appropriately located on the irrigation pipeline to prevent water-source 
contamination from backflow. 
2. The pesticide injection pipeline must contain a functional, automatic, quick-closing 
check valve to prevent the flow of fluid back toward the injection pump.

Alto 100SL 
Page 12 
3. The pesticide injection pipeline must also contain a functional, normally closed, 
solenoid-operated valve located on the intake side of the injection pump and 
connected to the system interlock to prevent fluid from being withdrawn from the 
supply tank when the irrigation system is either automatically or manually shut down. 
4. The system must contain functional interlocking controls to automatically shut off the 
pesticide injection pump when the water pump motor stops. 
5. The irrigation line or water pump must include a functional pressure switch which will 
stop the water pump motor when the water pressure decreases to the point where 
pesticide distribution is adversely affected. 
6. Systems must use a metering pump, such as a positive displacement injection pump 
(e.g., diaphragm pump), effectively designed and constructed of materials that are 
compatible with pesticides and capable of being fitted with a system interlock. 
7. Do not apply when wind speed favors drift beyond the area intended for treatment. 
 
4.5.3 SPECIFIC INSTRUCTIONS FOR PUBLIC WATER SYSTEMS 
1. Public water system means a system for the provision to the public of piped water for 
human consumption if such system has at least 15 service connections or regularly 
serves an average of at least 25 individuals daily at least 60 days out of the year. 
2. Chemigation systems connected to public water systems must contain a functional, 
reduced-pressure zone (RPZ) back-flow pr eventer or the functional equivalent in the 
water supply line upstream from the point of pesticide introduction. As an option to the 
RPZ, the water from the public water system should be discharged into a reservoir tank 
prior to pesticide introduction. There sh all be a complete physical break (air gap) 
between the outlet end of the fill pipe and the top or overflow rim of the reservoir tank 
of at least twice the inside diameter of the fill pipe. 
3. The pesticide injection pipeline must cont ain a functional, automatic, quick-closing 
check valve to prevent the flow of fluid back toward the injection pump. 
4. The pesticide injection pipeline must cont ain a functional, normally closed, solenoid-
operated valve located on the intake side of the injection pump and connected to the 
system interlock to prevent fluid from being withdrawn from the supply tank when the 
irrigation system is either automatically or manually shut down. 
5. The system must contain functional interlock ing controls to automatically shut off the 
pesticide injection pump when the water pump motor stops, or in cases where there is 
no water pump, when the water pressure de creases to the point where pesticide 
distribution is adversely affected. 
6. Systems must use a metering pump, such as a positive displacement injection pump 
(e.g., diaphragm pump), effectively designed and constructed of materials that are 
compatible with pesticides and capable of being fitted with a system interlock. 
7. Do not apply when wind speed favors drift beyond the area intended for treatment. 
 
4.5.4 APPLICATION DIRECTIONS FOR SPRINKLER IRRIGATION SYSTEMS 
x Chemical tank and injector system should be thoroughly cleaned. Flush system with 
clean water. 
x Apply this product through sprinkler irrigat ion systems including center pivot, lateral 
move, end tow, side [(wheel)] roll, traveler, big gun, solid set, or hand move irrigation 
systems.

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Page 13 
x Apply with center pivot or continuous-mo ve equipment distributing 1/2 acre-inch or 
less during treatment. In general, use the least amount of water required for proper 
distribution and coverage. 
x If stationary systems (solid set, handlines, or wheel lines other than continuous-
move) are used, this product should be injected into no more than the last 20-30 
minutes of the set. 
x Thorough coverage of foliage is required for good control. 
x Good agitation should be maintained during the entire application period.

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5.0 ROTATIONAL CROP RESTRICTIONS 
The following crops may be planted at the specified interval following application of Alto 
100SL Fungicide: 
 
Crop Plant-Back Interval 
Soybeans, corn, peanuts or wheat immediately, if crop is lost 
Cereal grains (other than wheat), cotton 180 days 
All other crops (including leafy 
vegetables) 270 days 
 
6.0 RESTRICTIONS AND PRECAUTIONS 
 
6.1 Use Restrictions 
x Do not use in nurseries or greenhouses. 
 
6.2 Use Precautions 
x Higher rates in the specified rate range and/or shorter spray intervals may be required 
under conditions of heavy infection pressure, highly susceptible varieties, or when 
environmental conditions are conducive to disease. 
x Under certain conditions conducive to extended infection periods, use another 
registered fungicide for additional applications if the maximum amount of product has 
been applied. 
x The active ingredient in this product may have effects on federally listed threatened 
and endangered species or critical habitat in some counties. When using this product, 
you must follow the measures contained in the county bulletin for the county in which 
you are applying the pesticide. Bulletins may be available from local pesticide 
dealers, extension offices, or state pesticide agencies. 
 
6.3 Spray Drift Advisories 
x THE APPLICATOR IS RESPONSIBLE FOR AVOIDING OFF-SITE SPRAY 
DRIFT. 
x BE AWARE OF NEARBY NON-TARGET SITES AND ENVIRONMENTAL 
CONDITIONS. 
 
 
6.3.1 IMPORTANCE OF DROPLET SIZE 
x An effective way to reduce spray drift is to apply large droplets. Use the largest 
droplets that provide target pest control. 
x While applying larger droplets will reduce spray drift, the potential for drift will be 
greater if applications are made improperly or under unfavorable environmental 
conditions.

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Page 15 
 
6.3.2 CONTROLLING DROPLET SIZE – GROUND BOOM 
 
x Volume - Increasing the spray volume so that larger droplets are produced will 
reduce spray drift. Use the highest practical spray volume for the application. If a 
greater spray volume is needed, consider using a nozzle with a higher flow rate. 
x Pressure - Use the lowest spray pr essure recommended for the nozzle to produce 
the target spray volume and droplet size. 
x Nozzle Type - Use a spray nozzle that is designed for the intended application. 
Consider using nozzles designed to reduce drift. 
 
 
6.3.3 CONTROLLING DROPLET SIZE – AIRCRAFT 
 
x Adjust Nozzles - Follow nozzle manufacturers ’ recommendations for setting up 
nozzles. Generally, to reduce fine droplets, nozzles should be oriented parallel 
with the airflow in flight. 
 
 
6.3.4 BOOM HEIGHT – GROUNDBOOM 
 
x For ground equipment, the boom should remain level with the crop and have 
minimal bounce. 
 
 
6.3.5 RELEASE HEIGHT – AIRCRAFT 
x Higher release heights increase the potential for spray drift. 
 
6.3.6 SHIELDED SPRAYERS 
 
x Shielding the boom or individual nozzles can reduce spray drift. Consider using 
shielded sprayers. Verify that the shields are not interfering with the uniform 
deposition of the spray on the target area. 
 
6.3.7 TEMPERATURE AND HUMIDITY 
x When making applications in hot and dry conditions, set up equipment to 
produce larger droplets to reduce effects of evaporation.

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6.3.8 TEMPERATURE INVERSIONS 
 
x Drift potential is high during a temperat ure inversion. Temperature inversions are 
characterized by increasing temperature with altitude and are common on nights 
with limited cloud cover and light to no wind. The presence of an inversion can 
be indicated by ground fog or by the movement of smoke from a ground source 
or an aircraft smoke generator. Smoke that layers and moves laterally in a 
concentrated cloud (under low wind conditions) indicates an inversion, while 
smoke that moves upward and rapidly dissipates indicates good vertical air 
mixing. Avoid applications during temperature inversions. 
 
6.3.9 WIND 
x Drift potential increases with wi nd speed. AVOID APPLICATIONS DURING 
GUSTY WIND CONDITIONS. 
x Applicators need to be familiar with local wind patterns and terrain that could 
affect spray drift.

Alto 100SL 
Page 17 
7.0 CROP USE DIRECTIONS 
7.1 Cereals 
Crops (Including all cultivars, varieties, and/or hybrids of these) 
Triticale Wheat 
Target Pest 
Rate 
(fl 
oz/A) Application Timing Use Directions 
Early season suppression 
of: 
Powdery mildew 
 (Blumeria spp., Erysiphe 
spp.) 
Leaf Blight 
 (Septoria tritici) 
Glume Blotch 
 (Stagonospora nordorum) 
Tan spot 
 ( Pyrenophora tritici-repentis) 
1.5–5.5 Apply in the spring at 
approximately Feekes Stage 
5. 
 
Apply by ground, air or 
chemigation. 
Control of Leaf Diseases: 
Rust 
 (Puccinia spp.) 
Powdery mildew 
 (Blumeria spp., Erysiphe 
spp.) 
Leaf Blight 
 (Septoria tritici) 
Glume Blotch 
 (Stagonospora nordorum) 
Tan spot 
 (Pyrenophora tritici-repentis) 
Helminthosporium leaf blight 
 (Drechslera tritici-repentis) 
Spot Blotch 
 (Bipolaris sorokiniana) 
 
Foot Rot 
 ( Pseudocercosporella spp.) 
3.0–5.5 Apply between Feekes Stage 
8 and 10.5.1. 
 
Apply at tillering, but before 
elongation has occurred. 
Apply by ground, air or 
chemigation. 
 
 
 
If disease pressure is 
low, apply 3 fl oz/acre. 
 
 
 
For Foot Rot control, 
apply Alto 100SL 
Fungicide in 
combination with other 
EPA-registered 
fungicides such as 
Topsin® M 
(thiophanate-methyl). 
Resistance Management: 
x Refer to Section 3.2. 
Precautions: 
x For leaf diseases, protecting the flag leaf is important for maximizing the potential yield. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 5.5 fl oz/A/application (0.036 lb ai/A of cyproconazole -
containing products) 
3) Minimum Application Interval: 14 days 
4) Maximum Annual Rate: 5.5 fl oz/A/year (0.036 lb ai/A/year of cyproconazole-containing products) 
5) Pre-Harvest Interval (PHI): 
a. Forage and Hay: 21 days 
b. Wheat (Grain and Straw): 30 days

Alto 100SL 
Page 18 
7.2 Corn 
Crops (Including all cultivars, varieties, and/or hybrids of these) 
Corn, field Corn, seed 
Target Pest 
Rate 
(fl oz/A) Application Timing Use Directions 
Northern corn leaf blight 
 (Setosphaeria turcica) 
 
Northern corn leaf spot 
 (Cochliobolus carbonum) 
 
Southern corn leaf blight 
 (Cochliobolus heterostrophus) 
[also known as 
Helminthosporium leaf blights 
 (H. maydis, H. turcicum, H. 
carbonum)] 
 
Rusts (common and Southern) 
 (Puccinia spp.) 
 
Gray leafspot 
 (Cercospora zeae-maydis) 
 
Eye spot 
 (Aureobasidium zeae) 
2.75–5.5 Apply when disease first 
appears. 
 
A second application may 
be made 7–14 days later. 
Apply by ground, air or 
chemigation 
 
Use the low rate when 
disease pressure is low. 
 
Apply the high specified 
rate under heavy disease 
pressure or if conditions 
are favorable for disease. 
Resistance Management: 
x Refer to Section 3.2. 
USE RESTRICTIONS 
1. Refer to Section 6.1 for additional product use restrictions. 
2. Maximum Single Application Rate: 5.5 fl oz/A/application (0.036 lb ai/A of cyproconazole-
containing products) 
3. Minimum Application Interval: 7 days 
4. Maximum Annual Rate: 5.5 fl oz/A/year (0.036 lb ai/A/year of cyproconazole-containing 
products) 
5. DO NOT apply more than 2 applications per year. 
6. Pre-Harvest Interval (PHI): 
a. Grain and Stover: 30 days 
b. Forage and Silage: 21 days

Alto 100SL 
Page 19 
7.3 Peanut 
Crops (Including all cultivars, varieties, and/or hybrids of these) 
Peanut 
Target Pest 
Rate 
(fl oz/A) Application Timing Use Directions 
Early leafspot 
 
(Cercospora arachidicola) 
 
Late leafspot 
 (Cercosporidium personatum) 
 
Rust 
 (Puccinia arachidis) 
 
Web blotch 
 (Phoma arachidicola) 
 
Southern stem blight 
 (Sclerotium rolfsii) 
 
Limb Rot 
 ( Rhizoctonia solani) 
5.5 A foliar disease control 
program should start 30 to 
45 days after planting or at 
the first appearance of 
disease.
 
 
For early season control of 
Southern stem blight, 
apply Alto100SL Fungicide 
or Alto100SL Fungicide + 
Abound® Flowable 
Fungicide (azoxystrobin), in 
a proportional banded spray 
7
-28 days after planting. 
 
Apply by ground, air or 
chemigation. 
 
For foliar disease control, apply 
up to two times as part of a 
season long disease 
management program. 
 
 
For increased control of 
Southern stem blight, tank mix 
5.5 fl oz/A with products intended 
for S. rolfsii at approximately 60 
and 90 days after planting. 
Resistance Management: 
x Refer to Section 3.2. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 5.5 fl oz/A/application (0.036 lb ai/A of cyproconazole-
containing products) 
3) Minimum Application Interval: 28 days 
4) Maximum Annual Rate: 11 fl oz/A/year (0.072 lb ai/A/year of cyproconazole-containing products) 
5) Pre-Harvest Interval (PHI): 30 days 
6) DO NOT apply more than 2 applications per year.

Alto 100SL 
Page 20 
7.4 Soybean 
Crops (Including all cultivars, varieties, and/or hybrids of these) 
Soybean 
Target Pest 
Rate 
(fl oz/A) Application Timing Use Directions 
Rust 
 (Phakopsora spp.) 
 
2.75–5.5 
 
For maximum performance, 
apply prior to disease 
development. 
 
For control of Rust, 
depending on the conditions, 
apply at R1 (beginning 
flowering, approximately 50 
days after planting) up to the 
R6 stage (seed fully 
developed). Repeat at 14- to 
28-day interval if conditions 
persist for rust development. 
Applications may be made by 
ground, air or chemigation. 
 
A spreading/penetrator type 
adjuvant is recommended when 
used solo or in tank mix. 
 
Coverage and penetration are 
important for best results. Use 
sufficient water volume to provide 
thorough and uniform plant 
coverage. 
 
For control of Rust while plants 
are in vegetative stages of 
growth, use the 2.75 oz/A 
rate. For rust control when the 
plants are in reproductive stages 
of growth use the 5.5 oz/A rate. 
 
For all other diseases, apply a 
minimum of 4 fl oz/A based on 
conditions and disease pressure. 
 
Tank mixes with a strobilurin 
fungicide such as Quadris will 
enhance performance on these 
diseases. 
 
Aerial blight 
 (Rhizoctonia solani) 
 
Frogeye leafspot 
 (Cercospora sojina) 
 
Anthracnose 
 (Colletotrichum truncatum) 
 
Alternaria leaf spot 
 (Alternaria spp.) 
 
Brown spot 
 (Septoria glycines) 
 
Cercospora blight and leaf spot 
 (Cercospora kikuchii) 
 
Pod and Stem blight 
 (Diaporthe phaseolorum) 
4.0–5.5 
Resistance Management: 
x Refer to Section 3.2. 
x Do not alternate or tank mix with fungicides to which resistance has developed in the pathogen 
population. 
USE RESTRICTIONS 
1) Refer to Section 6.1 for additional product use restrictions. 
2) Maximum Single Application Rate: 5.5 fl oz/A/application (0.036 lb ai/A of cyproconazole-
containing products) 
3) Minimum Application Interval: 14 days 
4) Maximum Annual Rate: 11 fl oz/A/year (0.072 lb ai/A/year of cyproconazole-containing products) 
5) DO NOT use soybean forage or hay as livestock feed if making more than one application at 5.5 fl 
oz product/A. 
6) DO NOT graze forage within 14 days of an application. 
7) Pre-Harvest Interval (PHI): 
a. Soybeans (bean): 30 days

Alto 100SL 
Page 21 
8.0 STORAGE AND DISPOSAL 
STORAGE AND DISPOSAL 
 
Do not contaminate water, food, or feed by storage or disposal. 
 
PESTICIDE STORAGE 
Store in original container only. Keep container closed when not in use. Do not store 
near food or feed. In case of spill on floor or paved surfaces, mop and remove to 
chemical waste storage area until proper disposal can be made if product cannot be 
used according to the label. 
 
PESTICIDE DISPOSAL 
Pesticide wastes are acutely hazardous. Improper disposal of excess pesticide, spray 
mixture, or rinsate is a violation of federal law. If these wastes cannot be disposed of by 
use according to label instructions, contact your state pesticide or environmental control 
agency, or the hazardous waste representative of the nearest EPA regional office for 
guidance. 
 
CONTAINER HANDLING (less than or equal to 5 gallons) 
Non-refillable container. Do not reuse or refill this container. Triple rinse container (or 
equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining 
contents into application equipment or a mix tank. Drain for 10 seconds after the flow 
begins to drip. Fill the container ¼ full with water and recap. Shake for 10 seconds. 
Pour rinsate into application equipment or a mix tank or store rinsate for later use and 
disposal. Drain for 10 seconds after the flow begins to drip. Repeat this procedure two 
more times. Then offer for recycling if available, or puncture and dispose of in a 
sanitary landfill, or by incineration, or by other procedures approved by state and local 
authorities. 
 
CONTAINER HANDLING (greater than 5 gallons) 
Refillable container. Refill this container with pesticide only. Do not reuse this container 
for any other purpose. Cleaning the container before final disposal is the responsibility 
of the person disposing of the container. Cleaning before refilling is the responsibility of 
the person refilling. To clean container before final disposal, empty the remaining 
contents from this container into application equipment or mix tank. Fill the container 
about 10 percent full with water. Agitate vigorously or re-circulate water with the pump 
for 2 minutes. Pour or pump rinsate into application equipment or rinsate collection 
system. Repeat this rinsing procedure two more times. Then offer for recycling if 
available or puncture and dispose of in a sanitary landfill, or by incineration, or by other 
procedures allowed by state and local authorities. 
 
CONTAINER IS NOT SAFE FOR FOOD, FEED, OR DRINKING WATER.

Alto 100SL 
Page 22 
9.0 CONDITIONS OF SALE AND LIMITATION OF WARRANTY 
AND LIABILITY 
NOTICE: Read the entire Directions for Use and Conditions of Sale and 
Limitation of Warranty and Liability before buying or using this product. If the 
terms are not acceptable, return the product at once, unopened, and the 
purchase price will be refunded. 
 
The Directions for Use of this product must be followed carefully. It is impossible to 
eliminate all risks inherently associated with the use of this product. Crop injury, 
ineffectiveness or other unintended consequences may result because of such factors 
as manner of use or application, weather or crop conditions, presence of other materials 
or other influencing factors in the use of the product, which are beyond the control of 
SYNGENTA CROP PROTECTION, LLC or Seller. To the extent permitted by 
applicable law, Buyer and User agree to hold SYNGENTA and Seller harmless for any 
claims relating to such factors. 
 
SYNGENTA warrants that this product conforms to the chemical description on the label 
and is reasonably fit for the purposes stated in the Directions for Use, subject to the 
inherent risks referred to above, when used in accordance with directions under normal 
use conditions. To the extent permitted by applicable law: (1) this warranty does not 
extend to the use of this product contrary to label instructions or under conditions not 
reasonably foreseeable to or beyond the control of Seller or SYNGENTA, and, (2) Buyer 
and User assume the risk of any such use. TO THE EXTENT PERMITTED BY 
APPLICABLE LAW, SYNGENTA MAKES NO WARRANTIES OF MERCHANTABILITY 
OR OF FITNESS FOR A PARTICULAR PURPOSE NOR ANY OTHER EXPRESS OR 
IMPLIED WARRANTY EXCEPT AS WARRANTED BY THIS LABEL. 
 
To the extent permitted by applicable law, in no event shall SYNGENTA be liable for 
any incidental, consequential or special damages resulting from the use or handling of 
this product. TO THE EXTENT PERMITTED BY APPLICABLE LAW, THE 
EXCLUSIVE REMEDY OF THE USER OR BUYER, AND THE EXCLUSIVE LIABILITY 
OF SYNGENTA AND SELLER FOR ANY AND ALL CLAIMS, LOSSES, INJURIES 
OR DAMAGES (INCLUDING CLAIMS BASED ON BREACH OF WARRANTY, 
CONTRACT, NEGLIGENCE, TORT, STRICT LIABILITY OR OTHERWISE) 
RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, SHALL BE THE 
RETURN OF THE PURCHASE PRICE OF THE PRODUCT OR, AT THE ELECTION 
OF SYNGENTA OR SELLER, THE REPLACEMENT OF THE PRODUCT. 
 
SYNGENTA and Seller offer this product, and Buyer and User accept it, subject to the 
foregoing Conditions of Sale and Limitation of Warranty and Liability, which may not be 
modified except by written agreement signed by a duly authorized representative of 
SYNGENTA.

Alto 100SL 
Page 23 
10.0 [OPTIONAL TABLE:] USE SUMMARY TABLE 
Crop or Crop 
Group or 
Subgroup, with 
examples 
Maximum 
Single 
Application 
Rate 
(fl oz/A) 
Maximum 
Single 
Application 
Rate 
(lb ai/A) 
Minimum 
Application 
Interval 
(days) 
Pre-Harvest 
Interval - PHI 
(days) 
Maximum 
Annual 
Rate 
(fl oz/A) 
Maximum 
Annual Rate 
(lb ai/A) 
Cereals 
Triticale and wheat 5.5 0.036 14 
Forage/Hay: 
21 
Wheat 
(Grain/Straw): 
30 
5.5 0.036 
Corn 
Field and seed 5.5 0.036 7 
Forage/Silage: 
21 
Grain/Stover: 
30 
5.5 0.036 
Peanut 5.5 0.036 28 30 11 0.072 
Soybean 5.5 0.036 14 Beans: 30 11 0.072

Alto 100SL 
Page 24 
Alto®, Abound®, the ALLIANCE FRAME, the SYNGENTA Logo, and the PURPOSE 
ICON are Trademarks of a Syngenta Group Company 
 
Topsin® M is a trademark of Nippon Soda Company, Ltd. 
Viton™ is a trademark of The Chemours Company FC, LLC. 
 
©20__ Syngenta 
 
 
For non-emergency (e.g., current product information), call 
Syngenta Crop Protection at 1-866-796-4368. 
 
 
Manufactured for: 
Syngenta Crop Protection, LLC 
P.O. Box 18300 
Greensboro, North Carolina 27419-8300 
 
 
Alto 100SL Fungicide 1226 MAS 0217 AMEND-B 1220-CL - jvb – 5/1/2024 
000100-01226.20201218B.ALTO_100SL_FUNGICIDE-AMEND-1220-CL.pdf