crop-chem-docs/corpus/epa_ppls/100-1527.md

# CRUISER VIBRANCE QUATTRO

- EPA Reg No: **100-1527**
- Registrant: SYNGENTA CROP PROTECTION, LLC
- Signal word: Caution
- Active ingredients: Thiamethoxam (5.75%); Fludioxonil (0.72%); Metalaxyl-M (0.86%); Difenoconazole (3.45%); Sedaxane (1.44%)
- Label accepted: 2019-09-20
- Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000100-01527-20190920.pdf

---
UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 
 WASHINGTON, DC 20460 
 
 
 
Reg Review Label Acceptable v.20151230 
OFFICE OF CHEMICAL SAFETY 
AND POLLUTION PREVENTION 
September 20, 2019 
 
Ricky Kyaw 
Regulatory Product Manager 
Syngenta Crop Protection, LLC 
PO Box 18300 
Greensboro, NC 27419 
 
Subject: Registration Review Label Mitigation for Fludioxonil and Mefenoxam 
 Product Name: Cruiser Vibrance Quattro 
 EPA Registration Number: 100-1527 
 Application Date: 2/1/2019 
Decision Number: 554968; 554969 
 
Dear Mr. Kyaw: 
 
The Agency, in accordance with the Federal Insecticide, Fungicide and Rodenticide Act 
(FIFRA), as amended, has completed reviewing all of the information submitted with your 
application to support the Registration Review of the above referenced product in connection 
with the Fludioxonil and Mefenoxam Interim Decisions, and has concluded that your submission 
is acceptable. The label referred to above, submitted in connection with registration under 
FIFRA, as amended, is acceptable. 
 
Should you wish to add/retain a reference to the company’s website on your label, then please be 
aware that the website becomes labeling under the Federal Insecticide Fungicide and Rodenticide 
Act and is subject to review by the Agency. If the website is false or misleading, the product 
would be misbranded and unlawful to sell or distribute under FIFRA section 12(a)(1)(E). 40 
CFR 156.10(a)(5) list examples of statements EPA may consider false or misleading. In addition, 
regardless of whether a website is referenced on your product’s label, claims made on the 
website may not substantially differ from those claims approved through the registration process. 
Therefore, should the Agency find or if it is brought to our attention that a website contains false 
or misleading statements or claims substantially differing from the EPA approved registration, 
the website will be referred to the EPA’s Office of Enforcement and Compliance. 
 
A copy of your label stamped “Accepted” is enclosed. Products shipped after 12 months from the 
date of this amendment must bear the new revised label. Your release for shipment of the 
product bearing the amended label constitutes acceptance of these conditions. If these conditions 
are not complied with, the registration will be subject to cancellation in accordance with FIFRA 
section 6.

Page 2 of 2 
EPA Reg. No. 100-1527 
Decision No. 554968; 554969 
 
If you have any questions about this letter, please contact Darius Stanton by phone at 703-347-
0433, or via email at Stanton.Darius@epa.gov
. 
 
 Sincerely, 
 
 
 
 Linda Arrington, Branch Chief 
 Risk Management and Implementation Branch 4 
 Pesticide Re-Evaluation Division 
 Office of Pesticide Programs 
 
 
 
Enclosure

(Master Label) 
THIAMETHOXAM GROUP 4A INSECTICIDE
DIFENOCONAZOLE GROUP 3 FUNGICIDE 
MEFENOXAM GROUP 4 FUNGICIDE 
SEDAXANE GROUP 7 FUNGICIDE 
FLUDIOXONIL GROUP 12 FUNGICIDE 
Cruiser® Vibrance® Quattro 
A seed treatment product for protection against damage from certain insects and 
diseases of small grain cereals. 
Active Ingredient: 
Thiamethoxam1. ...................................................................................................... 5.75% 
Difenoconazole2: ..................................................................................................... 3.45% 
Mefenoxam3: ........................................................................................................... 0.86% 
Fludioxonil4: ............................................................................................................. 0.72% 
Sedaxane5 ............................................................................................................... 1.44% 
Other Ingredients: 87.78% 
Total: 100.00% 
1CAS No. 153719-23-4 
2CAS No. 119446-68-3 
3CAS Nos. 70630-17-0 and 69516-34-3 
4CAS No. 131341-86-1 
5CAS No. 874967-67-6 
Cruiser Vibrance Quattro contains 0.51 lbs. thiamethoxam; 0.31 lbs. difenoconazole; 
0.08 lbs. mefenoxam; 0.06 lbs. fludioxonil and 0.13 lbs. sedaxane per gallon. 
 
KEEP OUT OF REACH OF CHILDREN. 
 
CAUTION 
See additional precautionary statements and directions for use in booklet [on label]. 
 
EPA Reg. No. 100-1527 
EPA Est. No. XXXXX 
 
SCP 1527-MAS 0615 
 
Net Contents
 
Sep 20, 2019
100-1527

-2- 
FIRST AID 
Have the product container with you when calling a poison control center or doctor, or 
going for treatment. 
HOT LINE NUMBER 
For 24-Hour Medical Emergency Assistance (Human or Animal) or 
Chemical Emergency Assistance (Spill, Leak, Fire, or Accident), 
Call 
1-800-888-8372 
 
 
PRECAUTIONARY STATEMENTS 
 
Personal Protective Equipment (PPE) 
 
Mixers, loaders, applicators and other handlers must wear: 
 
x Long-sleeved shirt and long pants 
x Shoes plus socks 
x Chemical-resistant gloves made of polyvinyl chloride [PVC] •14 mils, nitrile rubber 
•14 mils, butyl rubber •14 mils, barrier laminate, neoprene rubber •14 mils, natural 
rubber •14 mils, polyethylene, or Viton® •14 mils 
 
Follow manufacturer’s instructions for cleaning/maintaining PPE. If no such instructions 
for washables exist, use detergent and hot water. Keep and wash PPE separately from 
other laundry. 
 
Engineering Control Statements 
 
When handlers use closed systems in a manner that meets the requirements listed in 
the Worker Protection Standard (WPS) for agricultural pesticides [40 CFR 170.240(d)(4-
6)], the handler PPE requirements may be reduced or modified as specified in the WPS. 
 
 
User Safety Recommendations 
 
Users should: 
 
x Wash hands before eating, drinking, chewing gum, using tobacco, or using the 
toilet. 
x Remove clothing/PPE immediately if pesticides get inside. Then wash thoroughly 
and put on clean clothing. 
x Remove PPE immediately after handling this product. Wash the outside of gloves 
before removing. As soon as possible, wash thoroughly and change into clean 
clothing.

-3- 
 
Environmental Hazards 
This product is toxic to wildlife, freshwater and estuarine/marine fish and highly toxic to 
aquatic invertebrates. Runoff may be hazardous to aquatic organisms in neighboring 
areas. Exposed treated seed may be hazardous to wildlife. Do not contaminate water 
when disposing of equipment washwater or rinsate. 
 
Pollinator Precautions 
Thiamethoxam is highly toxic to bees, and effects are possible as a result of exposure 
to translocated residues in blooming crops. 
 
If treated seed is spilled outdoors or in areas accessible to birds, promptly clean up or 
bury to prevent ingestion. 
 
Ground Water Advisory 
Mefenoxam is known to leach through soil into ground water under certain conditions as 
a result of agricultural use. Use of this chemical in areas where soils are permeable, 
particularly where the water table is shallow, may result in ground water contamination. 
 
Thiamethoxam has properties and characteristics associated with chemicals detected in 
ground water. This chemical may leach into the ground water if used in areas where 
soils are permeable, particularly where the water table is shallow.

-4- 
CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY 
 
NOTICE: Read the entire Directions for Use and Conditions of Sale and Limitation of 
Warranty and Liability before buying or using this product. If the terms are not acceptable, 
return the product at once, unopened, and the purchase price will be refunded. 
 
The Directions for Use of this product must be followed carefully. It is impossible to 
eliminate all risks inherently associated with the use of this product. Crop injury, 
ineffectiveness or other unintended consequences may result because of such factors 
as manner of use or application, weather or crop conditions, presence of other materials 
or other influencing factors in the use of the product, which are beyond the control of 
SYNGENTA CROP PROTECTION, LLC or Seller. To the extent permitted by 
applicable law, Buyer and User agree to hold SYNGENTA and Seller harmless for any 
claims relating to such factors. 
 
SYNGENTA warrants that this product conforms to the chemical description on the label 
and is reasonably fit for the purposes stated in the Directions for Use, subject to the 
inherent risks referred to above, when used in accordance with directions under normal 
use conditions. To the extent permitted by applicable law: (1) this warranty does not 
extend to the use of the product contrary to label instructions or under conditions not 
reasonably foreseeable to or beyond the control of Seller or SYNGENTA, and (2) Buyer 
and User assume the risk of any such use. To the extent permitted by applicable law, 
SYNGENTA MAKES NO WARRANTIES OF MERCHANTABILITY OR OF FITNESS 
FOR A PARTICULAR PURPOSE NOR ANY OTHER EXPRESS OR IMPLIED 
WARRANTY EXCEPT AS WARRANTED BY THIS LABEL. 
 
To the extent permitted by applicable law, in no event shall SYNGENTA be liable for any 
incidental, consequential or special damages resulting from the use or handling of this 
product. TO THE EXTENT PERMITTED BY APPLICABLE LAW, THE EXCLUSIVE 
REMEDY OF THE USER OR BUYER, AND THE EXCLUSIVE LIABILITY OF 
SYNGENTA AND SELLER FOR ANY AND ALL CLAIMS, LOSSES, INJURIES OR 
DAMAGES (INCLUDING CLAIMS BASED ON BREACH OF WARRANTY, 
CONTRACT, NEGLIGENCE, TORT, STRICT LIABILITY OR OTHERWISE) 
RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, SHALL BE THE 
RETURN OF THE PURCHASE PRICE OF THE PRODUCT OR, AT THE ELECTION OF 
SYNGENTA OR SELLER, THE REPLACEMENT OF THE PRODUCT. 
 
SYNGENTA and Seller offer this product, and Buyer and User accept it, subject to the 
foregoing Conditions of Sale and Limitation of Warranty and Liability, which may not be 
modified except by written agreement signed by a duly authorized representative of 
SYNGENTA.

-5- 
DIRECTIONS FOR USE 
 
For commercial or on-farm use. 
 
It is a violation of Federal law to use this product in a manner inconsistent with its labeling. 
 
Do not apply this product in a way that will contact workers or other persons, either directly 
or through drift. Only protected handlers may be in the area during application. For any 
requirements specific to your State or Tribe, consult the agency responsible for pesticide 
regulation. 
 
FAILURE TO FOLLOW DIRECTIONS AND PRECAUTIONS ON THIS LABEL MAY 
RESULT IN CROP INJURY, POOR DISEASE CONTROL, AND/OR ILLEGAL 
RESIDUES. 
 
Treatment of highly mechanically scarred or damaged seed, or seed known to be of low 
vigor and poor quality, except for the purpose of curative control of existing disease 
pests, may result in reduced germination and/or reduction of seed and seedling vigor. 
Treat using equipment similar to that planned for treating the total seed lot. Conduct 
germination tests on a small portion of seed before committing the total seed lot to a 
selected seed treatment. Due to seed quality and seed storage conditions beyond the 
control of Syngenta, no claims are made to guarantee the germination of carry-over 
treated seed. 
 
Maximum usage when applying both metalaxyl- and mefenoxam-containing 
products to the same crop within the same season: Do not apply more than the 
maximum yearly total application rate for the active ingredient as stated on the label of 
the product containing the lowest yearly total on that crop. 
 
AGRICULTURAL USE REQUIREMENTS 
Use this product only in accordance with its labeling and with the Worker Protection 
Standard, 40 CFR part 170. This Standard contains requirements for the protection of 
agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of 
agricultural pesticides. It contains requirements for training, decontamination, 
notification, and emergency assistance. It also contains specific instructions and 
exceptions pertaining to the statements on this label about personal protective 
equipment (PPE), notifications to workers, and restricted-entry interval. The 
requirements in this box only apply to uses of this product that are covered by the 
Worker Protection Standard. 
 
Do not enter or allow worker entry into treated areas during the restricted-entry 
interval (REI) of 48 hours. Exception: If the seed is treated with the product and the 
treated seed is soil-injected or soil-incorporated, the Worker Protection Standard, under 
certain circumstances, allows workers to enter the treated area if there will be no 
contact with anything that has been treated.

-6- 
PPE required for early entry to treated areas that is permitted under the Worker 
Protection Standard and that involves contact with anything that has been treated, such 
as plants, soil, or water is: 
x Coveralls 
x Chemical-resistant gloves made of polyvinyl chloride [PVC] •14 mils, nitrile 
rubber •14 mils, butyl rubber •14 mils, barrier laminate, neoprene rubber •14 
mils, natural rubber •14 mils, polyethylene, or Viton® •14 mils 
x Shoes plus socks 
 
USE RESTRICTIONS 
 
x Do not use for feed, food, or oil purposes. 
x Store away from feeds and foodstuffs. 
x Wear long-sleeved shirt, long pants and chemical resistant gloves when handling 
treated seed. 
x Treated seeds exposed on soil surface may be hazardous to wildlife. Cover or 
collect treated seeds spilled during loading. 
x Do not allow children, pets, or livestock to have access to treated seed. 
x Dispose of all excess treated seed. Leftover treated seed may be doublesown 
around the headland or buried away from water sources in accordance with local 
requirements. 
x Do not contaminate water bodies when disposing of planting equipment wash 
waters. 
x Dispose of seed packaging in accordance with local requirements. 
x Treated seed must be planted into the soil at a depth greater than 0.5 inch. 
x For seed treated with Cruiser Vibrance Quattro, do not graze or feed livestock on 
treated areas for 45 days after planting. 
x In the event of a crop failure or harvest of a crop grown from Cruiser Vibrance 
Quattro treated seed, the field may be replanted immediately to canola, soybean, 
barley, oat, rye triticale and wheat, sweet corn, and chickpea. 
x Alfalfa, Brassica (cole) leafy vegetables, buckwheat, corn (except sweet corn), 
pearl millet, proso millet, popcorn, rice (dry-seeded), sorghum, teosinte, wild rice, 
cotton, cucurbit vegetables, dry bulb onions, fruiting vegetables, leafy vegetables, 
legume vegetables (except chickpea), mint (peppermint and spearmint), oil seed 
crops (black mustard seed, borage seed, crambe seed, field mustard seed, flax 
seed, Indian mustard seed, Indian rapeseed seed, peanuts, rapeseed seed, and 
safflower seed), root vegetables, strawberry, sunflowers, tobacco, and tuberous 
and corm vegetables may be planted 30 days from the date the Cruiser Vibrance 
Quattro treated seed was planted. 
x For any other crop, the minimum plant back interval is 120 days from the date the 
Cruiser Vibrance Quattro treated seed was planted. A cover crop other than the 
crops listed above that is planted for erosion control or soil improvement may be 
planted sooner than the 120 day interval; however, the crop may not be grazed 
or harvested for food or feed.

-7- 
x Do not make any soil or foliar application of products containing thiamethoxam to 
crops grown from seed treated with Cruiser Vibrance Quattro. 
x Do not use at a rate that will result in more than 0.05 lb thiamethoxam per acre 
(22.7 grams ai/A) per year as a seed treatment application. 
x Excess treated seed may be used for ethanol production only if (1) by-products 
are not used for livestock feed and (2) no measurable residues of pesticide 
remain in the ethanol by- products that are used in agronomic practice. 
 
PRODUCT INFORMATION 
 
Cruiser Vibrance Quattro is a seed treatment product containing one insecticide active 
ingredient (thiamethoxam) and four fungicide active ingredients (difenoconazole, 
mefenoxam, fludioxonil and sedaxane). Cruiser Vibrance Quattro seed treatment 
protects against damage from certain early-season insects and certain seed- and soil-
borne diseases of cereal crops. Difenoconazole provides protection against several 
seed, seedling and certain foliar disease including bunts and smuts. Mefenoxam 
protects against damping-off caused by Pythium. Fludioxonil provides protection 
against certain soil-borne and seed-borne diseases and is active against Fusarium, 
Rhizoctonia, and weakly pathogenic fungi such as Aspergillus and Penicillium
. 
Sedaxane protects against Rhizoctonia and loose smuts (Ustilago). 
 
Thiamethoxam is a systemic seed treatment insecticide belonging to the neoticotinoid 
class of chemistry. Thiamethoxam in Cruiser Vibrance Quattro protects against aphids, 
wireworm and European chafer. 
 
Cruiser Vibrance Quattro may be applied in tank mixes, or sequentially with other EPA-
registered seed treatment pesticide products. If using Cruiser Vibrance Quattro in a tank 
mixture with other seed treatment products, observe all directions for use, crops/sites, 
use rates, dilution ratios, precautions, and limitations which appear on the tank-mix 
partner label(s). Do not exceed any label dosage and follow the most restrictive label 
precautions and limitations. This product must not be mixed with any product which 
prohibits such mixing. 
 
MIXING INSTRUCTIONS 
 
Important: Always re-circulate Cruiser Vibrance Quattro thoroughly before using. 
 
Apply Cruiser Vibrance Quattro as a water-based slurry utilizing standard slurry seed 
treatment equipment which provides uniform seed coverage. Uneven or incomplete seed 
coverage may not give the desired level of insect and disease control. 
 
Consult the manufacturer of the application equipment you plan to employ for suitability 
for this application and for instructions on operation and calibration of the equipment. 
Follow the manufacturer application instructions for the seed treatment equipment being 
used.

-8- 
Continuous agitation or mixing of the slurry mixture is necessary to prevent settling out of 
the solution. 
 
Allow seed to dry before bagging. 
 
Follow planter manufacturer specifications for use of talc or other hopper box additives at 
planting. Seed must be completely dry before adding to planter. 
 
Cruiser Vibrance Quattro contains an EPA approved dye/colorant that imparts an 
unnatural color to the seed as required by the Federal Seed Act. 
 
SEED BAG LABEL REQUIREMENTS 
 
The Federal Seed Act requires that bags containing treated seeds shall be labeled with 
the following statements: 
x This seed has been treated with difenoconazole, mefenoxam, fludioxonil and 
sedaxane fungicides and thiamethoxam insecticide. 
x Do not use for feed, food, or oil purposes. 
x User is responsible for ensuring that the seed bag meets all requirements under 
the Federal Seed Act. 
 
In addition, the U.S. Environmental Protection Agency requires the following statements 
on bags containing seeds treated with Cruiser Vibrance Quattro: 
x Pollinator Precaution: 
Thiamethoxam is highly toxic to bees, and effects are possible as a result of 
exposure to translocated residues in blooming crops. 
x Ground Water Advisory: 
Mefenoxam is known to leach through soil into ground water under certain 
conditions as a result of agricultural use. Use of this chemical in areas where 
soils are permeable, particularly where the water table is shallow, may result in 
ground water contamination. 
Thiamethoxam has properties and characteristics associated with chemicals 
detected in ground water. This chemical may leach into the ground water if used 
in areas where soils are permeable, particularly where the water table is shallow.
 
x Store away from feeds and foodstuffs. 
x Wear long-sleeved shirt, long pants and chemical resistant gloves when handling 
treated seed. 
x Treated seeds exposed on soil surface may be hazardous to wildlife. Cover or 
collect treated seeds spilled during loading. 
x Do not allow children, pets, or livestock to have access to treated seed. 
x Dispose of all excess treated seed. Leftover treated seed may be doublesown 
around the headland or buried away from water sources in accordance with local 
requirements.

-9- 
x Do not contaminate water bodies when disposing of planting equipment wash 
waters. 
x Dispose of seed packaging in accordance with local requirements. 
x Treated seed must be planted into the soil at a depth greater than 0.5 inch. 
x For seed treated with Cruiser Vibrance Quattro, do not graze or feed livestock on 
treated areas for 45 days after planting. 
x In the event of a crop failure or harvest of a crop grown from Cruiser Vibrance 
Quattro treated seed, the field may be replanted immediately to canola, soybean, 
barley, oat, rye triticale and wheat, sweet corn, and chickpea. 
x Alfalfa, Brassica (cole) leafy vegetables, buckwheat, corn (except sweet corn), 
pearl millet, proso millet, popcorn, rice (dry-seeded), sorghum, teosinte, wild rice, 
cotton, cucurbit vegetables, dry bulb onions, fruiting vegetables, leafy vegetables, 
legume vegetables (except chickpea), mint (peppermint and spearmint), oil seed 
crops (black mustard seed, borage seed, crambe seed, field mustard seed, flax 
seed, Indian mustard seed, Indian rapeseed seed, peanuts, rapeseed seed, and 
safflower seed), root vegetables, strawberry, sunflowers, tobacco, and tuberous 
and corm vegetables may be planted 30 days from the date the Cruiser Vibrance 
Quattro treated seed was planted. 
x For any other crop, the minimum plant back interval is 120 days from the date the 
Cruiser Vibrance Quattro treated seed was planted. A cover crop other than the 
crops listed above that is planted for erosion control or soil improvement may be 
planted sooner than the 120 day interval; however, the crop may not be grazed 
or harvested for food or feed. 
x Do not make any soil or foliar application of products containing thiamethoxam to 
crops grown from seed treated with Cruiser Vibrance Quattro. 
x Do not use at a rate that will result in more than 0.05 lb thiamethoxam per acre 
(22.7 grams ai/A) per year as a seed treatment application. 
x This seed has been treated with 0.008 mg ai thiamethoxam per seed assuming 
an average seed size of 12,000 seeds per pound. 
x Excess treated seed may be used for ethanol production only if (1) by-products 
are not used for livestock feed and (2) no measurable residues of pesticide 
remain in the ethanol by- products that are used in agronomic practice. 
 
CROP USE PRECAUTIONS 
 
Resistance Management 
DIFENOCONAZOLE GROUP 3 FUNGICIDE 
MEFENOXAM GROUP 4 FUNGICIDE 
SEDAXANE GROUP 7 FUNGICIDE 
FLUDIOXONIL GROUP 12 FUNGICIDE 
 
For resistance management, please note that Cruiser Vibrance Quattro contains Group 
3/difenoconazole, Group 4/mefenoxam, Group 7/sedaxane, and Group 12/fludioxonil 
fungicides. Any fungal population may contain individuals naturally resistant to Cruiser 
Vibrance Quattro and other Group 3, Group 4, Group 7, or Group 12 fungicides. A

-10- 
gradual or total loss of pest control may occur over time if these fungicides are used 
repeatedly in the same fields. Appropriate resistance-management strategies should be 
followed. 
 
Difenoconazole belongs to the triazole class of chemistry and is a demethylation 
inhibitor of sterol biosynthesis (DMI) which disrupts membrane synthesis of the fungal 
cell. Mefenoxam belongs to the phenylamide class of chemistry which interferes with 
fungal RNA synthesis. Sedaxane is a succinate dehydrogenase inhibitor (SDHI) and 
belongs to the carboxamide class of chemistry which disrupts cellular respiration and 
energy generation. Fludioxonil belongs to the phenylpyrrole class of chemistry which 
interferes with osmotic signal transduction. 
 
To delay fungicide resistance, take one or more of the following steps: 
 
x Rotate the use of Cruiser Vibrance Quattro or other Group 3, Group 4, Group 7, 
or Group 12 fungicides within a growing season sequence with different groups 
that control the same pathogens. 
 
x Use tank mixtures with fungicides from a different group that are equally effective 
on the target pest when such use is permitted. Use at least the minimum 
application rate as labeled by the manufacturer. 
 
x Adopt an integrated disease management program for fungicide use that 
includes scouting, uses historical information related to pesticide use, and crop 
rotation, and which considers host plant resistance, impact of environmental 
conditions on disease development, disease thresholds, as well as cultural, 
biological and other chemical control practices. 
 
x Where possible, make use of predictive disease models to effectively time 
fungicide application. Note that using predictive models alone is not sufficient to 
manage resistance. 
 
x Monitor treated fungal populations for resistance development. 
 
x Contact your local extension specialist or certified crop advisor for any additional 
pesticide resistance-management and/or IPM recommendations for specific 
crops and pathogens. 
 
x For further information or to report suspected resistance contact Syngenta at 1-
866-SYNGENT(A) (866-796-4368). You can also contact your pesticide 
distributor or university extension specialist to report resistance. 
 
Syngenta encourages responsible product stewardship to ensure effective long term 
control of the fungal diseases on this label.

-11- 
THIAMETHOXAM GROUP 4A INSECTICIDE
 
 
Cruiser Vibrance Quattro contains a Group 4A insecticide (thiamethoxam, belonging to 
the neonicotinoid class of chemistry). Insect biotypes with acquired or inherent 
resistance to Group 4A insecticides may eventually dominate the insect population if 
Group 4A insecticides are used repeatedly as the predominant method of control for 
targeted species. This may result in partial or total loss of control of those species by 
thiamethoxam or other Group 4A insecticides. 
 
In order to maintain susceptibility to this class of chemistry: 
x Avoid using Group 4A insecticides exclusively for season long control of insect 
species with more than one generation per crop season. 
x For insect species with successive or overlapping generations, apply Cruiser 
Vibrance Quattro or other Group 4A insecticides using a “treatment window” 
approach. A treatment window is a period of time as defined by the stage of crop 
development and/or the biology of the pests of concern. Within the treatment 
window, depending on the length of residual activity, there may either be single or 
consecutive applications (seed treatment, soil, foliar, unless otherwise stated in the 
Directions for Use) of the Group 4A insecticides. When using Cruiser Vibrance 
Quattro seed treatment in the first treatment window rotate to effective products with 
a different mode of action in the subsequent treatment window before making 
additional applications of Group 4A insecticides. 
x A treatment window rotation, along with other IPM practices for the crop and use 
area, is considered an effective strategy for preventing or delaying a pest’s ability to 
develop resistance to this class of chemistry. 
x If resistance is suspected, do not reapply Cruiser Vibrance Quattro or any other 
Group 4A insecticides. 
 
Other Insect Resistance Management (IRM) practices include: 
x Incorporating IPM techniques into your insect control program. 
x Monitoring treated insect populations for loss of field efficacy. 
x Using tank-mixtures or premixes with insecticides from a different target site of 
action group as long as the involved products are all registered for the same crop 
outlet and effective rates are applied. 
 
For additional information on Insect Resistance Management: 
x Contact your local extension specialist, certified crop advisor and/or product 
manufacturer for additional insect resistance management recommendations. 
x Visit the Insecticide Resistance Action Committee (IRAC) on the web at: 
http://www.irac-online.org/. 
 
Consult your local pest control advisor or extension office for additional methods for 
preventing resistance development. Syngenta encourages responsible product 
stewardship to ensure effective long term control of the insect pests on this label.

-12- 
CROP USE DIRECTIONS 
 
Crop Protection Against the following Insects Use Rate 
Fluid Ounces per 100 lb 
seed 
Barley Aphids1 
European Chafer 
Wireworms1 
5 fluid oz 
 
Crop Protection Against the Following Diseases Use Rate 
Fluid Ounces per 100 lb 
seed 
Barley General Seed Rots2 
Seedling Blight, Root Rot, and Damping-Off 
caused by seed- and soil-borne Fusarium . or 
Rhizoctonia 
Seedling Blight, Root Rot, and Damping-Off 
caused by soil-borne Pythium 
Seed-borne Septoria 
Covered Smut 
False Loose Smut 
True Loose Smut 
5 fluid oz
 
 
Crop Diseases Suppressed3 Use Rate 
Fluid Ounces per 100 lb 
seed 
Barley Common Root Rot (Cochliobolus ) 
Fusarium Crown and Foot Rot 
Take-All 
5 fluid oz 
 
Crop Protection Against the following Insects Use Rate 
Fluid Ounces per 100 lb 
seed 
Oats Aphids1 
European Chafer 
Wireworms1 
5 fluid oz 
 
Crop Protection Against the Following Diseases Use Rate 
Fluid Ounces per 100 lb 
seed 
Oats General Seed Rots2 
Seedling Blight, Root Rot, and Damping-Off 
caused by seed- and soil-borne Fusarium or 
Rhizoctonia 
Seedling Blight, Root Rot, and Damping-Off 
caused by soil-borne Pythium 
Seed-borne Septoria 
Covered Smut 
Loose Smut 
5 fluid oz

-13- 
Crop Diseases Suppressed3 Use Rate 
Fluid Ounces per 100 lb 
seed 
Oats Common Root Rot (Cochliobolus) 5 fluid oz 
 
Crop Protection Against the following Insects Use Rate 
Fluid Ounces per 100 lb 
seed 
Rye Aphids1 
European Chafer 
Wireworms1 
5 fluid oz 
 
Crop Protection Against the Following Diseases Use Rate 
Fluid Ounces per 100 lb 
seed 
Rye General Seed Rots2 
Seedling Blight, Root Rot, and Damping-Off 
caused by seed- and soil-borne Fusarium or 
Rhizoctonia 
Seedling Blight, Root Rot, and Damping-Off 
caused by soil-borne Pythium 
Seed-borne Septoria 
Common Bunt
4 
Dwarf Bunt4 
5 fluid oz 
 
Crop Diseases Suppressed3 Use Rate 
Fluid Ounces per 100 lb 
seed 
Rye Common Root Rot (Cochliobolus) 
Fusarium Crown and Foot Rot 
Take-All 
5 fluid oz 
 
Crop Protection Against the following Insects Use Rate 
Fluid Ounces per 100 lb 
seed 
Winter Wheat Aphids1 
European Chafer 
Wireworms
1 
5 fluid oz 
 
Crop Protection Against the Following Diseases Use Rate 
Fluid Ounces per 100 lb 
seed 
Winter Wheat 
 and Triticale 
General Seed Rots2 
Seedling Blight, Root Rot, and Damping-Off 
caused by seed- and soil-borne Fusarium or 
Rhizoctonia 
Seedling Blight, Root Rot, and Damping-Off 
caused by soil-borne Pythium 
Seed-borne Septoria
 
Septoria Leaf Blotch5 
Common Bunt4 
Flag Smut 
5 fluid oz

-14- 
Fusarium Seed Scab 
Dwarf Bunt4 
Karnal Bunt 
Loose Smut 
Pythium Damping Off 
 
Crop Diseases Suppressed3 Use Rate 
Fluid Ounces per 100 lb 
seed 
Winter Wheat 
 and Triticale 
Common Root Rot (Cochliobolus) 
Fusarium Crown and Foot and Root Rot 
Take-All 
5 fluid oz 
 
Crop Protection Against the following Insects Use Rate 
Fluid Ounces per 100 lb 
seed 
Spring Wheat Aphids1 
European Chafer 
Wireworms
1 
5 fluid oz 
 
Crop Protection Against the Following Diseases Use Rate 
Fluid Ounces per 100 lb 
seed 
Spring Wheat General Seed Rots2 
Seedling Blight, Root Rot, and Damping-Off 
caused by seed- and soil-borne Fusarium or 
Rhizoctonia 
Seedling Blight, Root Rot, and Damping-Off 
caused by soil-borne Pythium 
Seed-borne Septoria
 
Fusarium Seed Scab 
Common Bunt4 
Karnal Bunt 
Loose Smut 
Pythium Damping Off 
5 fluid oz
 
 
Crop Diseases Suppressed3 Use Rate 
Fluid Ounces per 100 lb 
seed 
Spring Wheat Common Root Rot (Cochliobolus ) 
Fusarium Crown and Foot and Root Rot 
Take-All 
5 fluid oz 
 
1The 5 fluid oz/100 lbs rate of Cruiser Vibrance Quattro provides suppression of wireworm activity, aphids 
and aphid vectored barley yellow dwarf virus. If pressure is moderate or high or control is required, apply 
up to 0.8 fl. oz. additional Cruiser 5FS. 
 
2Protection against general seed rots. This includes rots caused by Fusarium , Pythium , Rhizoctonia , 
Penicillium and Aspergillus . 
3Suppression means consistent protection at a level which is not optimal but is still of commercial benefit. 
4Protects against both seed- and soil-borne bunts (common, dwarf). 
5Early season foliar disease protection for first 4 weeks after planting. For full season protection, apply a 
foliar fungicide according to label directions.

-15- 
STORAGE AND DISPOSAL 
 
Do not contaminate water, food or feed by storage and disposal. 
 
Pesticide Storage 
Store in original containers only. Keep container closed when not in use. Do not store 
near food or feed. In case of spill on floor or paved surfaces, mop and remove to chemical 
waste storage area until proper disposal can be made if product cannot be used according 
to the label. 
 
Pesticide Disposal 
Pesticide wastes are toxic. Improper disposal of excess pesticide, spray mixture, or 
rinsate is a violation of Federal law. If these wastes cannot be disposed of by use 
according to label instructions, contact your State Pesticide or Environmental Control 
Agency, or the Hazardous Waste representative of the nearest EPA Regional Office for 
guidance. 
 
Container Handling [less than 5 gallons] 
Non-refillable container. Do not reuse or refill this container. Offer for recycling if 
available. Triple rinse container (or equivalent) promptly after emptying. Triple rinse as 
follows: Empty the remaining contents into application equipment or a mix tank and drain 
for 10 seconds after the flow begins to drip. Fill the container ¼ full with water and recap. 
Shake for 10 seconds. Pour rinsate into application equipment or a mix tank or store 
rinsate for later use and disposal. Drain for 10 seconds after the flow beings to drip. 
Repeat this procedure two more times. Then offer for recycling if available or puncture 
and dispose of in a sanitary landfill, or by incineration, or by other procedures allowed by 
state and local authorities. 
 
Container Handling [greater than 5 gallons] 
Non-refillable container. Do not reuse or refill this container. Offer for recycling if 
available. Triple rinse container (or equivalent) promptly after emptying. Triple rinse as 
follows: Empty the remaining contents into application equipment or a mix tank. Fill the 
container ¼ full with water. Replace and tighten closures. Tip container on its side and 
roll it back and forth, ensuring at least one complete revolution, for 30 seconds. Stand 
the container on its end and tip it back and forth several ties. Turn the container over 
onto its other end and tip it back and forth several times. Empty the rinsate into application 
equipment or a mix tank or store rinsate for later use or disposal. Repeat this procedure 
two more times. Then offer for recycling if available or puncture and dispose of in a 
sanitary landfill, or by incineration, or by other procedures allowed by state and local 
authorities. 
 
Container Handling [greater than 5 gallons] 
Refillable container. Refill this container with pesticide only. Do not use this container 
for any other purpose. Cleaning the container before final disposal is the responsibility of 
the person disposing of the container. Cleaning before refilling is the responsibility of the 
refiller. To clean container before final disposal, empty the remaining contents from this

-16- 
container into application equipment or mix tank. Fill the container about 10 percent full 
with water. Agitate vigorously or recirculate water with the pump for 2 minutes. Pour or 
pump rinsate into application equipment or rinsate collection system. Repeat this rinsing 
procedure two more times. Then offer for recycling if available or puncture and dispose 
of in a sanitary landfill, or by incineration, or by other procedures allowed by state and 
local authorities. 
 
CONTAINER IS NOT SAFE FOR FOOD, FEED OR DRINKING WATER. 
 
 
Cruiser®, Vibrance®, the ALLIANCE FRAME, the SYNGENTA Logo and the 
PURPOSE ICON are Trademarks of a Syngenta Group Company 
 
Viton® trademark of E. I. du Pont de Nemours and Company 
 
©20XX Syngenta 
 
 
For non-emergency (e.g., current product information) call 
Syngenta Crop Protection at 1-800-334-9481. 
 
 
Manufactured for: 
Syngenta Crop Protection, LLC 
P.O. Box 18300 
Greensboro, North Carolina 27419-8300 
 
 
 
CRUISER VIBRANCE QUATTRO 1527 MAS 0615 AMEND 0518 – sb – 6/27/2018 
000100-01527.20180627.Cruiser Vibrance Quattro.AMEND.JUN2018