crop-chem-docs/corpus/epa_ppls/264-929.md

# 42-S THIRAM FUNGICIDE

- EPA Reg No: **264-929**
- Registrant: BAYER CROPSCIENCE, LLC
- Signal word: Caution
- Active ingredients: Thiram (42%)
- Label accepted: 2024-04-02
- Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000264-00929-20240402.pdf

---
Fast Track Label Acceptable (Highlighted/Indicated Changes) v.20240124
April 2, 2024
Anne Park
Regulatory Affairs Manager
Bayer Crop Science
800 N Lindbergh Blvd, St. Louis, MO 63167
Subject: Approval of Label Amendment; Only Indicated Changes Reviewed – Adding a 
restriction for onion/bulb as well as other minor edits.
 Product Name: 42-S Thiram Fungicide
 EPA Registration Number: 264-929
 Application Date: 3/10/2023
 Case Number: 479101
Dear Ms. Park:
The amended label referred to above, submitted in connection with registration under the 
Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), as amended, is acceptable.
However, EPA reviewed only the label changes highlighted, marked, or otherwise indicated on 
the submitted label. Any other changes to the previously approved label that were not clearly 
highlighted, marked, or otherwise indicated in your submission were not reviewed and may 
form the basis of regulatory and/or enforcement action if later discovered by the Agency. 
Further, submission of a label amendment application with unidentified changes may be 
considered a knowing submission of false information to the Agency. This approval does not 
affect any conditions that were previously imposed on this registration. You continue to be 
subject to existing conditions on your registration and any deadlines connected with them.
The label submitted with the application has been stamped “Accepted Only Indicated Revisions 
Reviewed” and is enclosed for your records. 
This labeling supersedes all previously accepted labeling. You must submit one copy of the final 
printed labeling before you release the product for shipment with the new labeling. In 
accordance with 40 C.F.R. § 152.130(c), you may distribute or sell this product under the 
previously approved labeling for 18 months from the date of this letter. After 18 months, you 
may only distribute or sell this product if it bears this new revised labeling or subsequently 
approved labeling. “To distribute or sell” is defined under FIFRA section 2(gg) and its 
implementing regulation at 40 C.F.R. § 152.3.

Page 2 of 2
EPA Reg. No. 264-929
Case Number 479101
Should you wish to add/retain a reference to the company’s website on your label, then please 
be aware that the website becomes labeling under FIFRA and is subject to review by the 
Agency. If the website contains any false or misleading statement, design, or graphic, the 
product may be misbranded and unlawful to sell or distribute under FIFRA Sections 2(q)(1)(A) 
and 12(a)(1)(E). 40 C.F.R. § 156.10(a)(5) lists examples of statements EPA may consider false or 
misleading. In addition, regardless of whether a website is referenced on the product label, 
claims made as part of the product’s sale or distribution may not substantially differ from those 
claims approved through the registration process under FIFRA Section 12(a)(1)(B). Therefore, 
should the Agency find or if it is brought to our attention that a website contains false or 
misleading statements or claims substantially differing from the EPA approved registration, the 
product will be referred to the EPA’s Office of Enforcement and Compliance Assurance.
Your release for shipment of the product constitutes acceptance of these conditions. If these 
conditions are not complied with, the registration will be subject to cancellation in accordance 
with FIFRA section 6. 
If you have any questions, please contact Sayed Islam at 202-566-2796 or at 
islam.sayed@epa.gov.
Sincerely,
Kable Bo Davis
Senior Regulatory Specialist
Office of Pesticide Programs
Registration Division, Immediate Office
Enclosure

1
42-S Thiram Fungicide
Intended for use by professional applicators only. 
Contains 4 lbs. thiram per gallon.
ACTIVE INGREDIENT:
Thiram (Tetramethylthiuram disulfide)..........................................................................................................................42.00%
OTHER INGREDIENTS: ............................................................................................................................. ................58.00%
TOTAL: 100.00%
EPA Reg. No. 264-929 EPA Est. 
KEEP OUT OF REACH OF CHILDREN
CAUTION
For MEDICAL And TRANSPORTATION Emergencies ONLY Call 24 Hours A Day 1-800-334-7577
For PRODUCT USE Information Call 1-866-99BAYER (1-866-992-2937)
Please refer to [back panel] [booklet] for additional precautionary statements and directions for use. [Note to 
reviewer: Location of additional precautionary statements and directions for use will vary between those listed, 
depending on container type/size.]
FIRST AID
IF SWALLOWED: • Call a poison control center or doctor immediately for treatment advice.
• Have person sip a glass of water if able to swallow.
• Do not induce vomiting unless told to do so by a poison control center or doctor.
• Do not give anything by mouth to an unconscious person.
IF ON SKIN OR 
CLOTHING:
• Take off contaminated clothing.
• Rinse skin immediately with plenty of water for 15-20 minutes.
• Call a poison control center or doctor for treatment advice.
IF INHALED: • Move person to fresh air.
• If person is not breathing, call 911 or an ambulance, and then give artificial respiration, preferably mouth-
to-mouth if possible.
• Call a poison control center or doctor for further treatment advice.
IF IN EYES: • Hold eye open and rinse slowly and gently with water for 15-20 minutes.
• Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye.
• Call a poison control center or doctor for treatment advice.
In case of emergency call toll free the Bayer CropScience Emergency Response Telephone No. 1-800-334-7577.
 Have a product container or label with you when calling a poison control center or doctor, or going for treatment.
264-929
04/02/2024

2
PRECAUTIONARY STATEMENTS
HAZARDS TO HUMANS AND DOMESTIC ANIMALS
CAUTION
Harmful if swallowed. Harmful if absorbed through skin. Harmful if inhaled. Avoid contact with eyes, skin, or clothing. Avoid b reathing 
spray mist or vapor. Prolonged or frequently repeated skin contact may cause allergic reactions in some individuals.
PERSONAL PROTECTIVE EQUIPMENT (PPE)
Some materials that are chemical-resistant to this product are made of any waterproof material. If you want more options, follo w the 
instructions for category A on an EPA chemical resistance category selection chart.
All mixers/loaders, applicators and other handlers must wear: 
- long-sleeved shirt and long pants, 
- shoes plus socks, 
- chemical resistant gloves,
- chemical resistant apron when mixing, loading, participating in dip treatments, cleaning up spills, cleaning equipment, or 
otherwise exposed to the concentrate.
NOTE: Persons involved in bagging treated seed, sewing or moving bags of treated seed, or cleaning up bagging areas or seed 
treatment equipment are pesticide handlers and must wear the PPE required on this label for pesticide handlers. 
USER SAFETY REQUIREMENTS
Follow manufacturer’s instructions for cleaning/maintaining PPE. If no such instructions for washables exist, use detergent and hot 
water. Keep and wash PPE separately from other laundry.
USER SAFETY RECOMMENDATIONS
Users should wash hands before eating, drinking, chewing gum, using tobacco or using the toilet. 
Users should remove clothing/PPE immediately if pesticide gets inside. Then wash thoroughly and put on clean clothing.
Users should remove PPE immediately after handling this product. Wash the outside of gloves before removing. As soon as possibl e, 
wash thoroughly and change into clean clothing.
ENDANGERED SPECIES
This bag contains seed treated with thiram. This product may have effects on federally listed threatened endangered species or their 
critical habitat in some counties. It is a violation of federal law to kill, harm or harass listed animal species without autho rization. To limit 
the potential for such impacts when using this product, consult and follow the instructions provided in the EPA Endangered Spec ies 
Bulletin for the County or Parish in which you are applying the seed. To determine whether your County or Parish has a Bulletin consult 
http://www.epa.gov/espp before each season's use of this product.
ENVIRONMENTAL HAZARDS
This pesticide is toxic to fish, aquatic invertebrates, oysters, and shrimp. Do not apply directly to water, or to areas where surface water 
is present or to intertidal areas below the mean high water mark. Drift and runoff from treated areas may be hazardous to aquat ic 
organisms in neighboring areas. Do not contaminate water when disposing of equipment washwater or rinsate or by disposal of wastes.
Treated seeds and bulbs are hazardous to fish, birds and mammals. Do not plant treated seeds or bulbs by broadcasting to the so il 
surface. Ensure that all seeds and bulbs are thoroughly covered with soil, especially in turn areas. If seeds or bulbs are not thoroughly 
incorporated by the planter during planting, additional incorporation may be required to thoroughly cover exposed seeds or bulbs.

3
DIRECTIONS FOR USE
It is a violation of Federal law to use this product in a manner inconsistent with its labeling.
Do not apply this product in a way that will contact workers or other persons. Only protected handlers may be in the area durin g 
application. For any requirements specific to your State or Tribe, consult the agency responsible for pesticide regulation.
AGRICULTURAL USE REQUIREMENTS
Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR part 170. This Standard contains 
requirements for the protection of agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of agricult ural 
pesticides. It contains requirements for training, decontamination, notification, and emergency assistance. It also contains sp ecific 
instructions and exceptions pertaining to the statements on this label about personal protective equipment (PPE), and restricte d-entry 
interval. The requirements in this box only apply to uses of this product that are covered by the Worker Protection Standard. D o not 
enter or allow worker entry into treated areas during the restricted entry interval (REI) of 24 hours. 
Exception: Once treated seeds or bulbs are planted in soil or other planting media, the Worker Protection Standard allows worke rs to 
enter the treated area without restriction, if there will be no contact with the treated seeds or bulbs. PPE required for early reentry to 
treated areas that is permitted under the Worker Protection Standard and that involves contact with anything that has been trea ted, 
such as plants, soil, or water, is: coveralls, shoes plus socks, chemical-resistant gloves made of any waterproof material, an d 
protective eyewear.
USE PRECAUTIONS AND RESTRICTIONS
When using formulations that do not contain dye, to comply with 40 CFR 153.155, all seed treated with an economic poison must b e 
colored to distinguish and prevent subsequent inadvertent use as a food for man or feed for animals.
For Treatment of Coniferous Seed
Damping-off protection: Use 2 quarts of 42-S Thiram Fungicide per 100 pounds of seed. Slowly add to the seed while turning in a 
tumbler such as a concrete mixer. Tumble seed for approximately 2 minutes and then spread coated seed on a screen to dry.
For the Treatment of Ornamental Bulbs, Corms and Tubers:
Treat any time after drying. Dip in a suspension made by mixing 1-1/2 pints of 42-S Thiram Fungicide in 8 gallons of water. Agi tate the 
suspension. If bulbs are to be stored, spread out to dry. Bulbs or tubers that are treated with this product must bear distinct labeling that 
instructs:
CAUTION: Treated with thiram. Wear rubber gloves and protective clothing when handling products treated with thiram. Direct 
exposure to skin may result in severe dermatitis.
Cotton Seed: The maximum application rate for cotton seed is 1.6 oz ai/cwt (1,000 ppm). Plant treated cotton seed a minimum of 1 
inch deep.
Barley Seed: Plant barley seed a minimum of 1 inch deep.
Oat Seed: Plant oat seed a minimum of 1 inch deep. 
Sugar Beet Seed: Plant sugar beet seed a minimum of 1 inch deep. 
Wheat Seed: Plant wheat seed a minimum of 1 inch deep. 
Onion Seed: When 1.5 lbs ai/cwt is used, the onion seed must undergo pelletized treatment.
RECOMMENDATIONS FOR USE AS A COMMERCIAL SEED TREATMENT
42-S Thiram Fungicide is a liquid fungicide recommended for the treatment of seeds listed in the following table. Used accordin g to 
directions, 42-S Thiram Fungicide will usually increase stands and yields by reducing losses from seed decay, damping-off and s eedling 
blights caused by many seedborne and soilborne organisms. 42-S Thiram Fungicide will usually control covered smuts or bunt of w heat, 
barley and rye and covered kernel smut of sorghum and will usually prevent basal rot and decay of ornamental bulbs and tubers. 42-S 
Thiram Fungicide aids in the control of Alternaria and Phoma on canola. 42-S Thiram Fungicide aids in the control of seedborne conidia 
produced from the honeydew inoculum from field infection of Claviceps africana (ergot) on sorghum seed.
For Slurry-Type Treater : 42-S Thiram Fungicide should be applied with water as a suspension in the slurry-type treater specifically 
designed and approved for this purpose.
For Film-Coating Operations : 42-S Thiram Fungicide has demonstrated good to excellent compatibility with most commercial film-
coating products. Coating procedures identified by polymer/coating companies and film-coating equipment manufacturers should be 
followed when preparing coating preparations containing 42-S Thiram Fungicide. If it is desirable to prepare slurries in large containers 
for addition to the slurry tank, entire contents should be thoroughly agitated before withdrawing any of the slurry.

4
SEEDS
42-S Thiram Fungicide 
Treating Rate Fluid Ounces 
Per Bushel Or 100 pound 
Weight
Barley, Millet, Oats**, Rye, Sorghum, Triticale**, Wheat 2/Bu.
Beans (Lima) and Peas 3/100 lbs
Beans (Snap & Dry, Soybeans, Cowpeas) 2/100 lbs.
Broccoli, Brussels Sprouts, Cabbage, Cauliflower, Collards, Kale, Kohlrabi, Mustard, Turnip 8/100 lbs.
Beet (Garden), Swiss Chard 8/100 lbs.
Canola** 6.4/100 lbs.
Cantaloupe, Cucumber, Pumpkin, Squash, Watermelon 4.5/100 lbs.
Carrot, Endive, Lettuce, Pepper, Radish, Spinach 8/100 lbs.
Castor beans** 4.5/100 lbs.
Chicory** 5.2/100 lbs.
Corn (Field) 1.5/Bu
Corn (Sweet) 5/100 lbs.
Cotton – acid – delinted 3/100 lbs.
Cotton – reginned and fuzzy 3/100 lbs.
Eggplant 6.5/100 lbs.
Flax 3/Bu.
Grasses 8/100 lbs.
Okra 6/100 lbs.
Onion 6/100 lbs.
Ornamental flower seed 8/100 lbs.
Peanuts* 3/100 lbs.
Rice (see For the Treatment of Rice Seed in CA specific directions) 1.5/Bu.
Safflower, Sunflower 2/Bu.
Sesame 3/100 lbs.
Small seed legumes 8/100 lbs.
Sugar beets 8/100 lbs.
Tomato 6/100 lbs.
*Note: In the treatment of peanuts, do not dilute with water
**Not registered for use in California
For the Treatment of Rice Seed in California
42-S Thiram Fungicide is a liquid fungicide recommended for the treatment of rice seed in California. Used according to directi ons, 
Thiram will usually increase stands and yields by reducing losses from seed decay, damping-off and seedling blights caused by 
seedborne and soilborne organisms.
42-S Thiram Fungicide is recommended for use on well cured rice seed in California prior to pre-plant soaking. 42-S Thiram Fung icide 
should be used with water as a suspension in treaters suitable for adequate mixing and accurate application to the seed. If it is desirable 
to prepare slurries in large containers for addition to treater tanks, entire contents should be thoroughly agitated before wit hdrawing any 
of the slurry for seed treatment.
How to Use: Rice seed treatment in California
SLURRY TREATERS:
Treater Tank Concentration Application Rate
Mix 1 gallon of 42-S Thiram Fungicide with 1 gallon of water 4 fluid ounces per 100 
pounds seed
MIST-O-MATIC TREATER:
Treater Tank Concentration Application Rate
Mix 1 gallon of 42-S Thiram Fungicide with 1 gallon of water. 4 fluid ounces per 100 
pounds seed

5
Note: To prevent water contamination in irrigation or drainage canals soak water should be 
retained in settling basins.
TREATED SEED
• Seeds or Bulbs that are treated with this product and are then packaged or bagged for future use by growers or researchers 
must contain the following labeling on the outside of the seed or bulb package or bag:
o This bag contains seeds or bulbs treated with 42-S Thiram Fungicide. thiram fungicide (42-S Thiram). When opening 
this bag or loading/pouring the treated seeds or bulbs wear long-sleeved shirt, long pants, shoes, socks and chemical 
resistant gloves.
o Treated seeds or bulbs. Do Not Use for Food, Feed or Oil Purposes.
o Store treated seed away from food and feedstuffs.
o Do not allow children, pets or livestock to have access to treated seeds.
o Treated seeds exposed on soil surface may be hazardous to wildlife. Cover or collect treated seeds spilled during 
loading and planting.
o Dispose of all excess treated seed by burying seed away from bodies of water.
o Dispose of seed packaging or containers in accordance with local requirements.
o “Endangered Species” section of this label must be included on the seed tag.
o After the seeds or bulbs have been planted, do not enter or allow worker entry into treated areas during the restricted-
entry interval (REI) of 24 hours. Exception: Once the seeds or bulbs are planted in soil or other planting media, the 
Worker Protection Standard allows workers to enter the treated area without restriction if there will be no worker 
contact with the seeds or bulbs.
o Treated seeds or bulbs are hazardous to fish, birds and mammals. Do not plant treated seeds or bulbs by 
broadcasting to the soil surface. Ensure that all seeds or bulbs are thoroughly covered with soil, especially in turn 
areas. If seeds or bulbs are not thoroughly incorporated by the planter during planting, additional incorporation may 
be required to thoroughly cover exposed seeds or bulbs. Do not apply directly to water, or to areas where surface 
water is present or to intertidal areas below the mean high water mark. Do not contaminate water when disposing of 
planting equipment washwater or rinsate or by disposal of wastes.
o Plant cotton, wheat, barley, oats, and sugar beet seed a minimum of 1 inch deep.
• Seeds or Bulbs that are treated with this product and are then packaged or bagged for future use by homeowners or other 
residential users must contain the following labeling on the outside of the seed or bulb package or bag:
o Treated seeds or bulbs. Do Not Use for Food, Feed or Oil Purposes.
STORAGE AND DISPOSAL
Do not contaminate water, food or feed by storage or disposal.
PESTICIDE STORAGE
Store in a cool place. Keep container tightly closed to prevent evaporation. Stir before using. DO NOT SUBJECT TO TEMPERATURES 
BELOW 32°F.
PESTICIDE DISPOSAL
Pesticide wastes are toxic. Improper disposal of excess pesticide, spray mixture, or rinsate is a violation of Federal law. If these wastes 
cannot be disposed of by use according to label instructions, contact your State Pesticide or Environmental Control Agency, or 
Hazardous Waste representative at the nearest EPA Regional Office for guidance
CONTAINER DISPOSAL
Rigid, Non-refillable containers small enough to shake (i.e., with capacities equal to or less than 5 gallons).
Non-refillable container. Do not reuse or refill this container. Offer for recycling, if available. Triple rinse container (or equivalent) 
promptly after emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank and dra in for 10 
seconds after the flow begins to drip. Fill the container 1/4 full with water and recap. Shake for 10 seconds. Pour rinsate int o application 
equipment or a mix tank or store rinsate for later use or disposal. Drain for 10 seconds after the flow begins to drip. Repeat this 
procedure two more times. Then offer for recycling or reconditioning or puncture and dispose of in a sanitary landfill, or incineration or, if 
allowed by state and local authorities, by burning. If burned, stay out of smoke.
Rigid Non-refillable containers that are too large to shake (i.e., with capacities greater than 5 gallons or 50 lbs).
50 gal and 200 gal
Non-refillable container. Do not reuse or refill this container. After emptying product from container, contact Bayer CropScience 
Customer Service Center (1-800-527-4781) with return authorization for container return instructions.
Cleaning the container before final disposal is the responsibility of the person disposing of the container. Offer for recycling, if available. 
Dispose of rinsed empty container in a sanitary landfill or by incineration, or if allowed by state and local authorities, by burning. If 
burned stay out of smoke.

6
IMPORTANT: READ BEFORE USE
Read the entire Directions for Use, Conditions, Disclaimer of Warranties and Limitations of Liability before using this product. If terms are 
not acceptable, return the unopened product container at once.
By using this product, user or buyer accepts the following Conditions, disclaimer of Warranties and Limitations of Liability.
Treatment of highly mechanically damaged seed, or seed of known low vigor and poor quality, may result in reduced germination a nd/or 
reduction of seed and seedling vigor. Treat and conduct germination tests on a small portion of seed before committing the tota l seed lot 
to a selected chemical treatment. Due to seed quality conditions beyond the control of Bayer CropScience, no claims are made to 
guarantee germination of carry-over seed.
CONDITIONS: The directions for use of this product are believed to be adequate and must be followed carefully. However, it is 
impossible to eliminate all risks associated with the use of this product. Crop injury, ineffectiveness or other unintended con sequences 
may result because of such factors as weather conditions, presence of other materials, or the manner of use or application, all of which 
are beyond the control of Bayer CropScience LP. All such risks shall be assumed by the user or buyer.
DISCLAIMER OF WARRANTIES: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER CROPSCIENCE LP MAKES 
NO WARRANTIES, EXPRESS OR IMPLIED, OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE OR 
OTHERWISE, THAT EXTEND BEYOND THE STATEMENTS MADE ON THIS LABEL. No agent of Bayer CropScience LP is authorized 
to make any warranties beyond those contained herein or to modify the warranties contained herein. TO THE EXTENT CONSISTENT 
WITH APPLICABLE LAW, BAYER CROPSCIENCE LP DISCLAIMS ANY LIABILITY WHATSOEVER FOR SPECIAL, INCIDENTAL OR 
CONSEQUENTIAL DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT.
LIMITATIONS OF LIABILITY: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE USER 
OR BUYER FOR ANY AND ALL LOSSES, INJURIES OR DAMA GES RESULTING FROM THE USE OR HANDLING OF THIS 
PRODUCT, WHETHER IN CONTRACT, WARRANTY, TORT, NEGLIGENCE, STRICT LIABILITY OR OTHERWISE, SHALL NOT 
EXCEED THE PURCHASE PRICE PAID, OR AT BAYER CROPSCIENCE LP’S ELECTION, THE REPLACEMENT OF PRODUCT.
NET CONTENTS: 
Produced for
Bayer CropScience LP
P.O. Box 12014, 2 T.W. Alexander Drive
Research Triangle Park, North Carolina 27709
1-866-99BAYER (1-866-992-2937)
42-S Thiram Fungicide (PENDING) 08/29/2018