crop-chem-docs/corpus/epa_ppls/524-479.md

# GENESIS HYBRIDIZING AGENT

- EPA Reg No: **524-479**
- Registrant: BAYER CROPSCIENCE, LLC
- Signal word: Caution
- Active ingredients: Clofencet (22.4%)
- Label accepted: 1997-02-26
- Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000524-00479-19970226.pdf

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u.s. 
Offlc. of Pest!c pr,(~~~, 
Regiltration Divilfon 
401 "MH St., S.Y. 
\Ia$hington. D.C. 20460 
NOTICE OF PESTICIDE: 
~ Registration 
____ Reregistration 
Oate of Issuance: 
524-479 
·~ .. 20_ 
Term of Iasu.nce: Conditional 
Nome of PesticIde Product: 
(under FI FRI., .s omended> Ganasis® 
Name of ZIP 
fM- ~5 
Monsanto 
700 14th 
company 
street, N ••• , suite 1100 
DC 20005 
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Registration Js in no way to be construed as an endorsement or reconmendatfon of this product by the Agency. In order to 
protect health and the envir-onnent. the Achinlstrator, on hil: motion, may at Wff tfme suspend or cancel the registration of • 
)t!C!de in oc:c:crdance with the Act. The acceptonc:e of any nome in comectlon with the registration of • prcxlJct under this 
f. not to be construed as gfvfng the registrant. right to exclusive use of the name or to ft, uae if It h .. been covered by 
other.. 
This product is conditionally registered in accordance with FIFRA sec. 
3(C)(7) (A) provided that you: 
1. Submit and/or cite all data required for registration of your product 
under FIFRA sec. 3(c)(5) when the Agency requires all registrants ot 
similar products to submit such data; and submit acceptable responses 
required for reregistration of your product under FIFRA section 4. 
2. Make the following label changes: 
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a. Revise the EPA Registration Number to read, "EPA Reg. No. 524-
479". 
b. In the MIXING INSTRUCTIONS section, under NOTE:, modify the 
statement as follows: "The use of a closed transfer system is 
required to be used by all mixer/loader and/or applicators if more 
than 50 acres are to be treated in a single day with Genesis· 
hybridizing agent." 
3. You must submit the following product chemistry data within one year of 
the date of registration: 
a. 61-2 starting Materials and Manufacturing Process: An amendment 
to the manufacturing process is required providing the complete 
details of the full scale equipment and operating conditions. 
continued on 2 
Date: 
Manager (25), Fungicide-Herbicide 
stration Division 
BEST AVAILABL.E COPY.

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page 2 
EPA Reg. No. 524-479 
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b. 61-3 Discussion of Impurities: A detailed discussion is required 
concerning the revised process control f purification and quality 
control procedures used in full scale production which resulted in 
the reduction of one impu,rity of concern to levels almost 10 times 
lower than the levels found in earlier pilot scale production: 
You must provide annual reports on production of end-use products 
containing clofencet, number of acres treated, and a best estimate of 
which crops and how many acres were planted as rotational crops on 
fields previously planted to wheat treated with clofencet. You must 
also provide field residue data on wheat grain, fora~, hay and straw 
from commercially treated crops beginning 18 months after the wheat 
grain is first.harvested. Field residue trials on the rotational crops 
listed in this document may also be required. The Agency will require 
periodic reevaluation of the dietary exposure, if warranted, with 
percent crop treated, number of acres of wheat treated and end-use 
product production information produced by you and other available 
sources, and submitted field residue data. You must petition the Agency 
before you increase production of cl~encet product for treatment of 
greater than 35,000 acres per year. ,- Before expansion beyond 0.1\ is 
allowed, reevaluation of the dietary exposure may be performed using all 
available information as necessary •. 
You must submit, upon EPA's request and according to a schedule 
determined by the Agency, such information as the Agency directs to be 
submitted in order to evaluate issues related to ,whether clofencet 
share(s) a common mechanism of toxicity with any other substance and, if 
so, whether any tolerances for clofencet need to be modified or revoked. 
Submit production information (pounds/gallons produced) for this product 
for the fiscal year in which the use on wheat are conditionally 
registered, in accordance with FIFRA Section 29. The conditional 
registration allows wheat rotated with the crops soybeans and cereal 
grains group (except rice, wild rice, sweet corn, and wheat). The 
fiscal year begins on october 1st and ends on September 30th. 
Production information will be submitted to the Agency no later than 
November 15th, following the end of the preceding fiscal year. This 
information should be submitted to: 
U.S. Environmental Protection Agency 
Office of Pesticide Programs (7404C) 
Document Processing Desk (RSB) 
401 M street, SW., (CM #2) 
Washington, DC 20460 
7. Submit two copies of the revised final printed label for the record. 
If these conditions are not complied with, the registration will be 
subject to cancellation in accordance with FIFRA sec. 6(e); Your release for 
shipment of the product constitutes acceptance of these conditions. 
A stamped copy of the label is enclosed for your records.

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For controlled a 
RESTRICTED USE CHEMICAL 
trained contract a plicators or cert . 
GENESIS@ 
HYBRIDIZING AGENT 
lJDd,w .... Federa:l1Dl1 dJeIde 
FagIcIde. aacI Bod_d" Act. aa am nil d. for the II •• tlc:JM 
,.ghoton<l - !f m RO<!". l!? 5J. - 7 
Genesis® hybridizing agent is a foliar applied compound used for the 
development of hybrid wheat. 
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Thjs label must be in the possession of the user at the time of application .. 
This product is not for sale to or use by any person oth~r than a licensee 
or contract seed grower. 
EPA Registration No. 524-UTO 
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1996-1 A-OOO.01 
Read the entire label before using this product. 
Use only according to label directions. 
Read "LIMIT OF WARRANTY AND LIABILITY" carefully before using. If the 
terms are not acceptable, retum the product at once unopened. . 
The contents of this container may not be REFORMULATED, nor, except in 
accordance with the Monsanto Repackaging Agreement, REPACKAGED. 
Genesis is a registered trademark of HybriTech Seed International; a 
subsidiary of Monsanto Company.

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liMIT OF WARRANTY AND LIABILITY 
This company warrants that this product conforms to the chemical 
description on the label and is reasonably fit for the purposes set forth in 
these Directions for Use ("Directions") when used in accordance with 
those Directions under the conditions described therein. NO OTHER 
EXPRESS WARRANTY OR IMPUED WARRANTY OF FITNESS FOR A PARTICULAR 
PURPOSE OR OF MERCHANTABIUTY IS MADE. This warranty is also subject 
to the conditions and limitations stated herein. 
Users assume all risks and are responsible for all loss or damage from use 
or handling which results from conditions beyond the control of this 
Company, including, but not limited to, incompatibility with products .. 
other than those set forth in the Directions, application to, drift to, or 
contact with nontarget crops, vegetation or property, weather and soil 
conditions, weather conditions which are outside the application ranges 
set forth in the Directions, application in any manner not explicitly set 
forth in the Directions, moisture conditions outside the moisture range 
specified in the Directions, or the presence of pests, disease, or other 
materials or products in or on the soil, crop, or treated vegetation. 
THE EXCLUSIVE REMEDY OF THE USER, AND THE UMIT OF THE UABIUTY OF 
THIS COMPANY FOR ANY AND ALL LOSSES, INJURIES OR DAMAGES RESULTING 
FROM THE USE OR HANDUNG OF THIS PRODUCT (INCLUDING CLAIMS BASED IN 
CONTRACT, NEGUGENCE, STRICT UABILITY, OTHER TORT OR OTHERWISE) 
SHALL BE THE REPLACEMENT OF THE QUANTITY OF THIS PRODUCT INVOLVED. 
IN NO EVENT SHALL THIS COMPANY BE UABLE FOR ANY INCIDENTAL, 
CONSEQUENTIAL OR SPECIAL DAMAGES. 
Licensees and contract seed growers are deemed to have accepted the 
terms of this UMIT OF WARRANTY AND UABIUTY by accepting, using and 
applying this product. These terms may not be varied by any verbal or 
written agreement.

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- PRECAUTIONARY STATEMENTS 
Hazards to Humans and Domestic Animals 
Keep out of reach of children. 
CAUTION! 
CAUSES EYE IRRITATION. 
Avoid contact with eyes or clothing. 
FIRST AID: IF It-J EYES, immediately flush with plenty of water. Get 
medical attention. 
Personal Protective Equipment 
Applicators and other handlers must wear long-sleeved shirt, long pants, 
and shoes plus socks. 
Follow manufacturer's instructions for cleaning/maintaining PPE. If no 
such instructions for washables, use detergent and hot water. Keep and 
wash PPE separately from other laundry. 
When handlers use enclosed cabs in a manner that meets the requirements 
listed in the Worker Protection Standard (WPS) for agricultural pesticides 
[40 CFR 170.240 (d) (4-6)], the handler PPE requirements may be reduced 
or modified as specified in the WPS. 
User Safety Recommendations: 
Users should: 
• Wash hands before eating, drinking, chewing gum, using tobacco or 
using the toilet. 
• Remove clothing immediately if pesticide gets inside. Then wash 
thoroughly and put on clean clothing. 
In case of an emergency involving this product, 
Call Collect, day or night, (314) 694-4000. 
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Environmental Hazards 
Do not apply directly to water, to areas where surface water is present or 
to intertidal areas below the mean high water mark. Do not contaminate 
water when disposing of equipment washwaters. 
This chemical demonstrates the properties and characteristics associated 
with chemicals detected in ground water. The use of this chemical in 
areas where soils are permeable, particularly where the water table is 
shallow, may result in ground water contamination. 
• Do not ap~y within 50 ft of small bodies of water (streams or 
ponds). 
• Do not apply to sand soils with less than 3% organic matter and a 
water table depth of less than 30 ft. 
• When using the compound on coarse-textured soils, do not apply 
within 100 feet of any drinking water well that is screened at a 
depth of 50 ft or less. 
Genesis has a high potential to leach to ground water in highly permeable 
soils (permeability >6 in/hr) or other soils rated by the Natural Resources 
Conservation Service (NRCS) as having a severe leaching potential. The 
potential for ground water contamination is greater in areas where the 
water table depth is less than 30 feet. 
This product may not be mixed or loaded within 50 feet of any wells 
(including abandoned wells and drainage wells), sink holes, perennial or 
intermittent streams and rivers, and natural or impounded lakes and 
reservoirs. This setback does not apply to properly capped or plugged 
abandoned wells and does not apply to impervious pad or properly diked 
mixing/loading areas. 
Operations that involve mixing, loading, rinsing or washing of this product 
into or from pesticide handling or application equipment or containers 
within 50 feet of any well are prohibited unless conducted on an 
impervious pad constructed to withstand the weight of the heaviest load 
that may be positioned on or moved across the pad. Such a pad shall be 
designed and maintained to contain any product spills or equipment leaks,

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container or equipment rinse or washwater, and rainwater that may fall 
on the pad. Surface water shall not be allowed to either flow over or from 
the pad, which means the pad must be self contained. The pad shall be 
sloped to facilitate material removal. An unroofed pad shall be of 
sufficient capacity to contain at a minimum 110%· of . the capacity of the 
largest pesticide container or application equipment on the pad. A pad 
that is covered by a roof of sufficient size to completely exclude 
precipitation from contact with the pad shall have a minimum 
containment capacity of 100% of the capacity of the largest pesticide 
container or application equipment on the pad. Containment capacities as 
described above shall be maintained at all times. The above specified 
minimum containr;pent capacities do not apply to vehicles when delivering 
pe?ticide shipments to the mixing/loading site. States may have in effect 
additional requirements regarding wellhead setbacks and operational 
containment. 
Genesis can contaminate surface water through spray drift. 
Under some conditions, Genesis may also have a high potential for runoff 
into s\lrface water (primarily via dissolution il'! runoff water) for several 
months post-application. These conditions include poorly-draining or wet 
soils with readily visible slopes toward adjacent surface waters, 
frequently-flooded areas, areas overlaying extremely shallow ground 
water, areas with in-field canals or ditches that drain to surface water, 
areas not separated from adjacent surface waters with vegetated filter 
strips, and areas overlaying tile drainage systems that drain to surface 
water. 
Applications should not be made to a field that is less than 500 feet from 
large bodies of water. 
""!Ii ~"-
ACTIVE INGREDIENT: 
[2- (4-ch lorophenyl) -3-ethyl-2, 5-dihyd ro-5-oxo-4-
pyridazinecarboxylic acid, potassium salt] ........................................... 22.4% 
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INERT INGREDIENTS: ....................................................................................................... 77.6"/0 
TOTAL 100.0%

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DIRECTIONS FOR USE 
It is a violation of Federal law to use this product in any 
manner inconsistent with its labeling. 
Do not apply this product in a way that will contact workers or other 
persons, either directly or through drift. Only protected handlers may be 
in the area during application. For any requirements specific to your State 
or Tribe, consult the agency responsible for pesticide regulation. 
AGRICUL ruRAL USE REQUIREMENTS 
-Us.e this product only in accordance with its labeling and with the Worker 
Protection Standard, 40 CFR part 170. This standard contains 
requirements for the protection of workers on farms, forests, nurseries, 
and greenhouses, and handlers of agricultural pesticides. It contains 
requirements for training, decontamination, notification and emergency 
assistance. It also contains specific instructions and exceptions 
pertaining to the statements on this label about personal protective 
equipment (PPE) and restricted-entry interval. The requirements in this 
box only apply to uses of this product that are covered by the Worker 
Protection Standard. 
Do not enter or allow worker entry into treated areas during the 
restricted entry interval (REI) of 12 hours. 
PPE required for early entry to treated areas that is permitted under the 
Worker Protection Standard and that involves contact with anything that 
has been treated, such as plants, soil, or water is: coveralls, waterproof 
gloves and shoes plus socks. 
For more product information, call toll-free 1 (800) 332-3111.

STORAGE AND DISPOSAL 
Do not contaminate water, foodstuffs, feed or seed by storage or disposal. 
STORAGE: Do not store below 400F or above 120oF. 
DISPOSAL: Wastes resulting from the use of this product that cannot be 
used by a licensee or contract grower in accordance with this label or 
chemically reprocessed by the manufacturer should be disposed of in a 
landfill approved for pesticide disposal or in accordance· with applicable 
Federal, state or local procedures. 
Emptied container contains vapor and product residue. Observe all labeled 
safeguards until container is cleaned, reconditioned or destroyed. 
Do not reuse this container, except for refill in accordance with a valid 
Monsanto Repackaging or Toll Repackaging Agreement. If not refilled or 
returned to an authorized repackaging. facility, triple rinse container, then 
puncture and dispose of in a sanitary landfill, or by incineration, or if 
allowed by state and local authorities, by burning. If container is burned, 
stay out of smoke. 
GENERAL INFORMATION 
Genesis is a hybridizing agent which can completely suppress pollen 
development in _wheat. This property makes it possible to use Genesis to 
produce hybrid wheat. Genesis is an effective hybridizing agent on a broad 
spectrum of wheat cultivars. 
Genesis hybridizing agent is formulated as a water soluble concentrate 
(WSC) containing 2 pounds of active ingredient per gallon of product. The 
use of a non ionic surfactant and a humectant, both cleared for application 
on wheat, is essential. The surfactant should be used at a maximum rate 
of 1 percent of carrier volume, and the humectant at a maximum rate of 2 
percent of carrier volume. Thorough spray coverage of wheat foliage is 
essential. The use of the nonionic surfactant and humectant will aid spray 
coverage and wetting of the foliage which will improve uptake.

MIXING INSTRUCTIONS 
NOTE: The use of a mechanical transfer system is required to be used by 
all mixerlloader and/or applicators if more than 50 acres are to be 
treated in a single day with Genesis hybridizing agent. 
Apply Genesis hybridizing agent at a rate not to exceed 10 pounds active 
ingredient per acre. CONSULT YOUR HYBRITECH SEED INTERNATIONAL 
TECHNICAL REPRESENTATIVE FOR ASSISTANCE WITH SPECIFIC USE 
RATES AND THE RECOMMENDED GROWTH STAGE OF DEVELOPMENT 
TO ACHIEVE MAXIMUM MALE PLANT STERILITY. Fill the spray tank 
with water to about two-thirds of the total volume to be sprayed. Add the 
required amount ()f Genesis hybridizing agent, surfactant and humectant, 
mix thoroughly and continue filling the spray tank. If needed, an anti-
''! foaming agent may be added to the tank mixture at a rate of 0.5 percent or 
less of carrier volume. Maintain sufficient agitation during mixing and 
spraying to ensure a uniform spray mixture. 
APPLICATION RECOMMENDATIONS 
Apply Genesis hybridizing agent to wheat with ground equipment only. Use 
low-pressure, low-drift flat fan nozzles. A shield should be mounted on 
each end of the spray boom to prevent direct spraying of outer rows of 
male parent strips. Apply Genesis only to the female parent which is 
planted in alternating strips between the male parent strips. The width of 
the male and female strips is dependent upon production efficiency and 
agronomic requirements of each hybrid. The female and male parent strips 
should be harvested separately and in such a manner as to avoid possible 
mixing of any treated female seed with male seed. Calibrate spray 
equipment to deliver 3 to 50 gallons of spray mixture per acre. A spray 
pressure of 15 to 30 psi at the nozzle tip is recommended when using the 
recommended low-pressure, low-drift flat fan nozzles. Adjust the height 
of the spray boom above the wheat to give complete coverage of foliage. 
The high gallonage will provide the necessary coverage of foliage and the 
low pressure will reduce drift onto the male parent strips. When 
spraying, avoid combinations of pressure and nozzle type that win result 
in fine particles (mist) which are likely to result in spray drift. Do not 
apply under wind or other conditions which allow drift to. occur. For 
further information on optimum spray pressure for specific nozzles, refer 
to the manufacturer of the nozzles. 
Application of Genesis must be made at least 45 days prior to the harvest 
of the hybrid wheat seed. 
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TIMING OF APPLICATION 
Apply Genesis to wheat between tip emergence of the penultimate leaf 
(Feekes Scale 7.0, Zadoks Scale 32) and emergence of the flag leaf ligule 
(Feekes Scale 9.0, Zadoks Scale 39).' The timing of the application is 
dependent upon factors such as variety, temperature, humidity and 
available soil moisture. Consequently, it' is necessary to pay close 
attention to development stages after the wheat enters its early spring, 
vigorous growth stage. Do not apply Genesis when temperatures fall 
below 320F or exceed 100oF. Do not spray if rainfall is anticipated within 
24 hours after application. If rainfall occurs within 24 hours after 
application, reapplication is permitted, with the total of all applications 
including the reapplications not to exceed 10 pounds of active ingredient 
per acre. Consult your HybriTech Seed International technical 
representative for assistance with specific use rates and growth stage 
determinations. 
ROTATIONAL CROP GUIDELINES 
Following the application of Genesis to wheat, rotate treated areas only 
to cereal grains (except sweet corn, rice or wild rice) and soybeans. . . 
Allowable cereal grains rotations include wheat, barley, buckwheat, 
corn (fleld-, seed- and pop-corn), millet (proso, and pearl), oats, 
rye, sorghum, teosinte and triticale. 
EPA Reg. No. 524-UTO A-000.01 
© MONSANTO COMPANY 1996 
In case of an emergency involving this product, Call Collect, day or' night, 
(314) 694-4000. 
MONSANTO COMPANY 
AGRICULTURAL PRODUCTS 
ST. LOUIS, MISSOURI 63167 U.S.A.