crop-chem-docs/corpus/epa_ppls/100-1459.md

# SYT0113

- EPA Reg No: **100-1459**
- Registrant: SYNGENTA CROP PROTECTION, LLC
- Signal word: Caution
- Active ingredients: Thiamethoxam (20%); Fludioxonil (1%); Metalaxyl-M (5.99%); Sedaxane (1%)
- Label accepted: 2026-06-22
- Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000100-01459-20260622.pdf

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June 22, 2026 
Patsy Laird
Regulatory Manager, Seedcare
Syngenta Crop Protection, LLC
P.O. Box 18300
Greensboro, NC 27419
Subject: Label Amendment - Registrat ion Review Mitigation for Sedaxane
Product Name: SYT0113 
EPA Registration Number: 100-1459
Application Date: February 13, 2026
Case Number: 684857
Dear Mrs. Patsy Laird:
The Agency, in accordance with the Federal Insecticide, Fungicide, and Rodenticide Act 
(FIFRA), as amended, has completed reviewing all the information submitted with your 
application to support the Registration Review of the above referenced product in 
connection with the Sedaxane Interim Decision, and has concluded that your submission 
is acceptable. The label referred to above, submitted in connection with registration under 
FIFRA, as amended, is acceptable.
Should you wish to add/retain a reference to the company’s website on your label, then 
please be aware that the website becomes labeling under the Federal Insecticide, 
Fungicide, and Rodenticide Act and is subject to review by the Agency. If the website is
false or misleading, the product would be misbranded and unlawful to sell or distribute 
under FIFRA section 12(a)(1)(E). 40 CFR 156.10(a)(5) list examples of statements EPA may 
consider false or misleading. In addition, regardless of whether a website is referenced on 
your product’s label, claims made on the website may not substantially differ from those 
claims approved through the registration process. Therefore, should the Agency find or if it 
is brought to our attention that a website contains false or misleading statements or 
claims substantially differing from the EPA approved registration, the website will be 
referred to the EPA’s Office of Enforcement and Compliance Assurance.

Page 2 of 2 
EPA Reg. No. 100-1459 
Decision No. 684857 
A stamped copy of your labeling is enclosed for your records. This labeling 
supersedes all previously accepted labeling and must be used at your next label 
printing. You must submit one copy of the final printed labeling before you release 
the product for shipment with the new labeling. In accordance with 40 CFR 
152.130(c), you may distribute or sell this product under the previously approved 
labeling for 12 months from the date of this letter. After 12 months, you may only 
distribute or sell this product if it bears this new revised labeling or subsequently 
approved labeling. “To distribute or sell” is defined under FIFRA section 2(gg) and 
its implementing regulation at 40 CFR 152.3. 
If you have any questions about this letter, please contact Samantha Carter by phone at 
202-566-1179, or via email at carter.samantha@epa.gov.
Sincerely, 
Jaclyn Pyne, Team Leader 
Risk Management and Implementation Branch 3 
Pesticide Re-Evaluation Division 
Office of Pesticide Programs
 
ENCLOSURE: Stamped label

(Master label)
THIAMETHOXAM GROUP 4A INSECTICIDE
MEFENOXAM GROUP 4 FUNGICIDE
SEDAXANE GROUP 7 FUNGICIDE
FLUDIOXONIL GROUP 12 FUNGICIDE
SYT0113
Insecticide with Fungicides
A seed treatment product for protection against damage from listed insects, seed-borne 
diseases, and seedling diseases on soybean
Active Ingredients:
Thiamethoxam
1 ............................................................................. 20.00 %
Mefenoxam2 .................................................................................... 5.99 %
Fludioxonil3...................................................................................... 1.00 %
Sedaxane4....................................................................................... 1.00 %
Other Ingredients: 72.01 %
Total: 100.00 %
1CAS No. 153719-23-4
2CAS No. 70630-17-0 and CAS No. 69516-34-3
3CAS No. 131341-86-1
4CAS No. 874967-67-6
One gallon of SYT0113 contains 1.90 lb thiamethoxam, 0.57 lb mefenoxam, 0.09 lb
fludioxonil and 0.09 lb sedaxane.
KEEP OUT OF REACH OF CHILDREN.
CAUTION
See additional precautionary statements and directions for use in booklet [on label].
EPA Reg. No. 100-1459
EPA Est. XXXXX
Net Contents
Jun 22, 2026
100-1459

2
FIRST AID 
If swallowed x Call a poison control center or doctor immediately for 
treatment advice. 
x Have person sip a glass of water if able to swallow. 
x Do not induce vomiting unless told to do so by the poison 
control center or doctor. 
x Do not give anything by mouth to an unconscious 
person. 
Have the product container or label with you when calling a poison control center 
or doctor or going for treatment. 
HOTLINE NUMBER 
For 24-Hour Medical Emergency Assistance (Human or Animal) 
Or Chemical Emergency Assistance (Spill, Leak, Fire or Accident) 
Call 
1-800-888-8372 
 
 
PRECAUTIONARY STATEMENTS 
 
Hazards to Humans and Domestic Animals 
 
CAUTION 
 
Harmful if swallowed. Wash thoroughly with soap and water after handling, and before 
eating, drinking, chewing gum, using tobacco, or using the toilet. 
 
Personal Protective Equipment (PPE) 
 
 
Applicators and other handlers must wear: 
 
x Long-sleeved shirt and long pants 
 
x Chemical-resistant gloves made of barrier laminate, butyl rubber t 14 mils, nitrile 
rubber t 14 mils, neoprene rubber t 14 mils, polyvinyl chloride (PVC) t 14 mils, or 
Viton™ t 14 mils 
 
x Shoes plus socks 
 
Follow manufacturer’s instructions for cleaning/maintaining PPE. If no such instructions 
exist for washables, use detergent and hot water. Keep and wash PPE separately from 
other laundry.

3
 
Engineering Control Statements 
 
When handlers use closed systems in a manner that meets the requirements listed in 
the Worker Protection Standard (WPS) for agricultural pesticides (40 CFR 170.607 (d) 
and (e)), the handler PPE requirements may be reduced or modified as specified in the 
WPS. 
 
User Safety Recommendations 
 
Users should: 
 
x Wash hands before eating, drinking, chewing gum, using tobacco, or using the 
toilet. 
x Remove clothing/PPE immediately if pesticide gets inside. Then wash 
thoroughly and put on clean clothing. 
 
Environmental Hazards 
 
This product is toxic to wildlife, freshwater and estuarine/marine fish and highly toxic to 
aquatic invertebrates. Runoff may be hazardous to aquatic organisms in neighboring 
areas. Exposed treated seed may be hazardous to wildlife. Do not contaminate water 
when disposing of equipment washwater or rinsate. 
 
Pollinator Precautions: 
Thiamethoxam is highly toxic to bees exposed to direct treatment, and effects may be 
possible as a result of exposure to translocated residues in blooming crops. 
 
Groundwater Advisory: 
Thiamethoxam has properties and characteristics associated with chemicals detected in 
groundwater. This chemical may leach into the groundwater if used in areas where 
soils are permeable, particularly where the water table is shallow. 
 
Mefenoxam is known to leach through soil into groundwater under certain conditions as 
a result of agricultural use. Use of this chemical in areas where soils are permeable, 
particularly where the water table is shallow, may result in groundwater contamination. 
 
Physical and Chemical Hazards 
 
Do not use, pour, spill or store near heat or open flame. Do not store near or use with 
oxidizing agents.

4
CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY 
 
NOTICE: Read the entire Directions for Use and Conditions of Sale and Limitation of 
Warranty and Liability before buying or using this product. If the terms are not 
acceptable, return the product at once, unopened, and the purchase price will be 
refunded. 
The Directions for Use of this product must be followed carefully. It is impossible to 
eliminate all risks inherently associated with the use of this product. Ineffectiveness or 
other unintended consequences may result because of such factors as manner of use 
or application, presence of other materials or other influencing factors in the use of the 
product, which are beyond the control of SYNGENTA CROP PROTECTION, LLC or 
Seller. To the extent permitted by applicable law, Buyer and User agree to hold 
SYNGENTA and Seller harmless for any claims relating to such factors. 
 
SYNGENTA warrants that this product conforms to the chemical description on the label 
and is reasonably fit for the purposes stated in the Directions for Use, when used in 
accordance with directions under normal use conditions. To the extent permitted by 
applicable law: (1) this warranty does not extend to the use of the product contrary to 
label instructions, or under conditions not reasonably foreseeable to or beyond the 
control of Seller or SYNGENTA, and, (2) Buyer and User assume the risk of any such 
use. TO THE EXTENT PERMITTED BY APPLICABLE LAW, SYNGENTA MAKES NO 
WARRANTIES OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR 
PURPOSE NOR ANY OTHER EXPRESS OR IMPLIED WARRANTY EXCEPT AS 
WARRANTED BY THIS LABEL. 
 
To the extent permitted by applicable law, in no event shall SYNGENTA be liable for 
any incidental, consequential or special damages resulting from the use or handling of 
this product. TO THE EXTENT PERMITTED BY APPLICABLE LAW, THE 
EXCLUSIVE REMEDY OF THE USER OR BUYER, AND THE EXCLUSIVE LIABILITY 
OF SYNGENTA AND SELLER FOR ANY AND ALL CLAIMS, LOSSES, INJURIES 
OR DAMAGES (INCLUDING CLAIMS BASED ON BREACH OF WARRANTY, 
CONTRACT, NEGLIGENCE, TORT, STRICT LIABILITY OR OTHERWISE) 
RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, SHALL BE THE 
RETURN OF THE PURCHASE PRICE OF THE PRODUCT OR, AT THE ELECTION 
OF SYNGENTA OR SELLER, THE REPLACEMENT OF THE PRODUCT. 
 
SYNGENTA and Seller offer this product, and Buyer and User accept it, subject to the 
foregoing Conditions of Sale and Limitation of Warranty and Liability, which may not be 
modified except by written agreement signed by a duly authorized representative of 
SYNGENTA.

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DIRECTIONS FOR USE 
 
It is a violation of federal law to use this product in a manner inconsistent with its 
labeling. 
 
For use in commercial seed treatment facilities. Use is also permitted as an end-use 
seed treatment on agricultural establishments at planting, or immediately before 
planting, as specified in the Specific Crop Use Directions. This product is to be used in 
liquid or slurry treaters only. 
 
Maximum usage when applying both metalaxyl- and mefenoxam-containing 
products to the same crop within the same season: Do not apply more than the 
maximum yearly total application rate for the active ingredient as stated on the label of 
the product containing the lowest yearly total on that crop. 
 
AGRICULTURAL USE REQUIREMENTS 
 
Use this product only in accordance with its labeling and with the Worker 
Protection Standard, 40 CFR part 170. This Standard contains requirements for 
the protection of agricultural workers on farms, forests, nurseries, and 
greenhouses, and handlers of agricultural pesticides. It contains requirements 
for training, decontamination, notification, and emergency assistance. It also 
contains specific instructions and exceptions pertaining to the statements on this 
label about personal protective equipment (PPE) and restricted-entry interval. 
The requirements in this box only apply to uses of this product that are covered 
by the Worker Protection Standard. 
 
Do not enter or allow worker entry into treated areas during the restricted-
entry interval (REI) of 48 hours. Exception: If the seed is treated with the 
product and the treated seed is soil-injected or soil-incorporated, the Worker 
Protection Standard, under certain circumstances, allows workers to enter the 
treated area if there will be no contact with anything that has been treated. 
 
PPE required for early entry to treated areas that is permitted under the Worker 
Protection Standard and that involves contact with anything that has been 
treated, such as plants, soil, or water is: 
 
x Coveralls 
x Chemical-resistant gloves made of barrier laminate, butyl rubber t 14 mils, 
nitrile rubber t 14 mils, neoprene rubber t 14 mils, polyvinyl chloride 
(PVC) t 14 mils, or Viton t 14 mils 
x Shoes plus socks

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FAILURE TO FOLLOW THE DIRECTIONS FOR USE AND PRECAUTIONS ON THIS 
LABEL MAY RESULT IN CROP INJURY, POOR INSECT AND/OR DISEASE 
CONTROL, AND/OR ILLEGAL RESIDUES. 
 
Treatment of highly mechanically scarred or damaged seed or seed known to be of low 
vigor and poor quality may result in reduced germination and/or reduction of seed and 
seedling vigor. Treat a quantity of seed using equipment similar to that planned for 
treating the total seed lot. Prior to treatment, conduct germination tests on a portion of 
seed before committing the total seed lot to a selected seed treatment. 
 
Due to seed quality, crop or variety sensitivity, and seed storage conditions beyond the 
control of Syngenta, no claims are made to guarantee the germination of seed or 
propagating material for all crop seed when treated with SYT0113. 
 
USE INFORMATION 
 
SYT0113 is a seed treatment product containing the active ingredients: thiamethoxam 
(insecticide) and fludioxonil, mefenoxam and sedaxane (fungicides). SYT0113 protects 
against damage from listed early season insects, soil-borne and seed-borne diseases of 
soybeans. 
 
Thiamethoxam is a systemic seed treatment insecticide belonging to the neonicotinoid 
class of chemistry. Thiamethoxam protects against listed chewing and sucking insects 
through contact and ingestion. 
 
Mefenoxam fungicide is active against Pythium, Phytophthora and systemic downy 
mildew. 
 
Fludioxonil fungicide is active against Fusarium, Rhizoctonia, and suppresses seed-
borne Sclerotinia and Phomopsis species. 
 
Sedaxane fungicide is active against seed decay, seedling blight and damping-off 
caused by Rhizoctonia species. 
 
Resistance Management 
MEFENOXAM GROUP 
4 FUNGICIDE 
SEDAXANE GROUP 7 FUNGICIDE 
FLUDIOXONIL GROUP 12 FUNGICIDE 
 
Fungicide Resistance Management 
 
For resistance management, please note that SYT0113 contains Group 4/mefenoxam, 
Group 7/sedaxane, and Group 12/fludioxonil fungicides. Any fungal population may 
contain individuals naturally resistant to SYT0113 and other Group 4, Group 7, or Group 
12 fungicides. A gradual or total loss of pest control may occur over time if these

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fungicides are used repeatedly in the same fields. Appropriate resistance-management 
strategies should be followed. 
 
Mefenoxam belongs to the phenylamide class of chemistry which interferes with fungal 
RNA synthesis. Sedaxane is a succinate dehydrogenase inhibitor (SDHI) and belongs 
to the carboxamide class of chemistry which disrupt cellular respiration and energy 
generation. Fludioxonil belongs to the phenylpyrrole class of chemistry which interferes 
with osmotic signal transduction. 
 
To delay fungicide resistance, take one or more of the following steps: 
 
x Rotate the use of SYT0113 or other Group 4, Group 7, or Group 12 fungicides 
within a growing season sequence with different groups that control the same 
pathogens. 
x Use tank mixtures with fungicides from a different group that are equally effective 
on the target pest when such use is permitted. Use at least the minimum 
application rate as labeled by the manufacturer. 
x Adopt an integrated disease management program for fungicide use that 
includes scouting, uses historical information related to pesticide use, and crop 
rotation, and which considers host plant resistance, impact of environmental 
conditions on disease development, disease thresholds, as well as cultural, 
biological and other chemical control practices. 
x Where possible, make use of predictive disease models to effectively time 
fungicide application. Note that using predictive models alone is not sufficient to 
manage resistance. 
x Monitor treated fungal populations for resistance development. 
x Contact your local extension specialist or certified crop advisor for any additional 
pesticide resistance-management and/or IPM recommendations for specific 
crops and pathogens. 
x For further information or to report suspected resistance contact Syngenta at 1-
866-SYNGENT(A) (866-796-4368). You can also contact your pesticide 
distributor or university extension specialist to report resistance.
 
Syngenta encourages responsible product stewardship to ensure effective long-term 
control of the fungal diseases on this label. 
 
THIAMETHOXAM GROUP 
4A INSECTICIDE 
 
Insecticide Resistance Management 
 
SYT0113 contains a Group 4A insecticide (thiamethoxam, belonging to the 
neonicotinoid class of chemistry). Insect biotypes with acquired or inherent resistance 
to Group 4A insecticides may eventually dominate the insect population if Group 4A 
insecticides are used repeatedly as the predominant method of control for targeted

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species. This may result in partial or total loss of control of those species by SYT0113 
or other Group 4A insecticides. 
 
Thiamethoxam is a systemic insecticide belonging to the neonicotinoid class of 
chemistry which includes nicotinic acetylcholine receptor (nAChR) agonists. 
 
To delay insecticide resistance, take the following steps: 
x Rotate the use of SYT0113 or other Group 4A insecticides within a growing 
season, or among growing seasons, with different groups that control the same 
pests. 
x Use tank mixtures with insecticides from a different group that are equally 
effective on the target pest when such use is permitted. Do not rely on the same 
mixture repeatedly for the same pest population. Consider any known cross-
resistance issues (for the targeted pests) between the individual components of a 
mixture. In addition, consider the following recommendations provided by the 
Insecticide Resistance Action Committee (IRAC): 
o Individual insecticides selected for use in mixtures should be highly 
effective and be applied at the rates at which they are individually 
registered for use against the target species. 
o Mixtures with components having the same IRAC mode of action 
classification are not recommended for insect resistance management. 
o When using mixtures, consider any known cross-resistance issues 
between the individual components for the targeted pest(s). 
o Mixtures become less effective if resistance is already developing to one 
or both active ingredients, but they may still provide pest management 
benefits. 
o The insect resistance management benefits of an insecticide mixture are 
greatest if the two components have similar periods of residual insecticidal 
activity. Mixtures of insecticides with unequal periods of residual 
insecticide activity may offer an insect resistance management benefit 
only for the period where both insecticides are active. 
x Adopt an integrated pest management program for insecticide/acaricides use 
that includes scouting, uses historical information related to pesticide use, crop 
rotation, record keeping, and which considers cultural, biological and other 
chemical control practices. 
x Monitor after application for unexpected target pest survival. If the level of 
survival suggests the presence of resistance, consult with your local university 
specialist or certified pest control advisor. 
x Contact your local extension specialist or certified crop advisors for any 
additional pesticide resistance-management and/or IPM recommendations for 
the specific site and pest problems in your area. 
x For further information or to report suspected resistance contact Syngenta at 1-
866-796-4368.

9
Syngenta encourages responsible product stewardship to ensure effective long term 
control of the insects on this label. 
 
MIXING PROCEDURES 
 
Important: Always re-circulate SYT0113 thoroughly before using. 
 
The typical density of SYT0113 is 9.48 pounds per gallon. Consult the manufacturer of 
the application equipment you plan to use for suitability for this application and for 
instructions on operation and calibration of the equipment. Follow the manufacturer 
application instructions for the seed treatment equipment being used. 
 
Apply SYT0113 as a water-based slurry utilizing standard slurry seed treatment 
equipment which provides uniform seed coverage. Uneven or incomplete seed 
coverage may not give the desired level of disease control. Thoroughly mix the 
specified amount of SYT0113 into the required amount of water or liquid inoculant for 
the slurry treater and dilution rate to be used. 
 
Certain crops require addition of inoculants when the seed is treated or planted. 
SYT0113 is compatible with several liquid inoculant products. Consult the maker of the 
inoculant product and a Syngenta Crop Protection representative for directions before 
applying SYT0113 with inoculants. 
 
The total application volume must be sufficient to provide desired level of coverage. 
Dilution is typically done with water or liquid inoculants. The minimum slurry volume to 
achieve adequate coverage is 4.0 fluid ounces per 100 pounds of seed. More diluent 
may be required to obtain complete coverage. 
 
Continuous agitation or mixing of the slurry mixture is necessary to prevent settling out 
of the solution. 
 
Allow seed to dry before bagging. 
 
Follow planter manufacturer specifications for use of talc or other hopper box additives 
at planting. Seed must be completely dry before adding to planter. 
 
Required Dye Statement: Seed treated with this product must be visually identifiable 
from untreated seed by the use of an approved colorant or dye to prevent accidental 
use of treated seed as food for humans or feed for animals. Refer to 21 CFR, Part 2.25. 
Any colorant or dye added to treated seed must be cleared for use in accordance with 
40 CFR, Part 153.155(c).

10 
SEED BAG LABEL REQUIREMENTS 
 
Use of On-Farm Treated Seed (when treated seed are not for sale or distribution) 
Treated seed sold or distributed for a use not permitted by the following labeling does 
not qualify as an exempted treated article under 40 CFR 152.25(a) and is therefore sale 
or distribution of an unregistered pesticide, pursuant to FIFRA section 12. 
 
x Store treated seed away from food and feedstuffs. 
x DO NOT allow children, pets, or livestock to have access to treated seed. 
x Treated seed are for planting purposes only. DO NOT use for food, feed, or oil 
purposes. DO NOT use treated seed for fuel or ethanol production purposes. 
x Wear long-sleeved shirt, long pants, sh oes, socks, and chemical-resistant gloves 
when handling treated seed. 
x DO NOT plant treated seed by broadcasting to the soil surface. Ensure that all 
planted seeds are thoroughly incorporated by the planter during planting. Additional 
incorporation may be required to thoroughly cover exposed seeds. 
x Treated seed exposed on the soil surface may be hazardous to wildlife. Cover or 
collect treated seed spilled during loading and planting (such as in row ends). 
x Treated seed must be planted into the soil at a depth greater than 1 inch. 
x Manage excess treated seed (e.g., spilled, unused, or expired treated seed) by one 
or more of the following methods: 
o Collect excess treated seed for reuse for planting. 
o Bury excess treated seed (only allowed if totaling 1 pound or less) at least 30 feet 
away from bodies of water at a depth of 6 inches or double the planting depth, 
whichever is greater. 
o Dispose of excess treated seed by placing them in a landfill in accordance with 
applicable laws in your state. 
o Return excess treated seed to the supplier if permitted by the state. 
x DO NOT contaminate bodies of water when disposing of equipment wash water. 
x Advisory Dust-Reducing Technique: The use of seed flow lubricants or polymer 
coatings may help decrease the amount of dust released during planting. Follow the 
recommendations of the planter manufacturer regarding the use of seed flow 
lubricants.

11 
Seed Treatment in Commercial Facilities or Seed Treatment on Farm (when 
treated seed are to be sold or distributed) – Seed Bag Labeling Requirements 
 
The Federal Seed Act requires that bags containing treated seed shall be labeled with 
the following statements: 
x This seed has been treated with thiamethoxam insecticide and fludioxonil, 
mefenoxam, and sedaxane fungicides. 
x DO NOT use for food, feed, or oil purposes. 
 
The U.S. Environmental Protection Agency requires that bags containing treated seed 
shall be labeled with the following statements. Any seed treated with SYT0113 that is 
sold or distributed without these statements or that is sold or distributed for a use not 
permitted by the following labeling does not qualify as an exempted treated article under 
40 CFR 152.25(a) and is therefore sale or distribution of an unregistered pesticide, 
pursuant to FIFRA section 12(a)(1)(A). 
 
This seed has been treated with SYT0113 (EPA Reg No. 100-1459) containing 
fludioxonil, mefenoxam, sedaxane, and thiamethoxam. Any seed treated with SYT0113 
that is sold or distributed for a use not permitted by the following labeling does not 
qualify as an exempted treated article under 40 CFR 152.25(a) and is therefore sale or 
distribution of an unregistered pesticide, pursuant to FIFRA section 12(a)(1)(A). 
 
 
x The contents of this bag are for planting purposes only. DO NOT use for food, 
feed, or oil purposes. DO NOT use for fuel or ethanol production purposes. 
x Store treated seed away from food and feedstuffs. 
x DO NOT allow children, pets, or livestock to have access to treated seed. 
x Wear long-sleeved shirt, long pants and chemical-resistant gloves when handling 
treated seed. 
x DO NOT plant treated seed by broadcasting to the soil surface. Ensure that all 
planted seeds are thoroughly incorporated by the planter during planting. 
Additional incorporation may be required to thoroughly cover exposed seeds. 
x Treated seed exposed on soil surface may be hazardous to wildlife. Cover or 
collect treated seed spilled during loading and planting (such as in row ends). 
x Treated seed must be planted into the soil at a depth greater than 1 inch. 
x Manage excess treated seed (e.g., spilled, unused, or expired treated seed) by 
one or more of the following methods: 
o Collect excess treated seed for reuse for planting. 
o Bury excess treated seed (only allowed if totaling 1 pound or less) at least 30 
feet away from bodies of water at a depth of 6 inches or double the planting 
depth, whichever is greater. 
o Dispose of excess treated seed by placing them in a landfill in accordance 
with applicable laws in your state. 
o Return excess treated seed to the supplier if permitted by the state. 
x DO NOT contaminate water bodies when disposing of planting equipment wash 
waters.

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x Dispose of seed packaging in accordance with local requirements. 
x For seed treated with SYT0113, DO NOT graze or feed livestock on treated 
areas for 45 days after planting. 
x In the event of a crop failure or harvest of a crop grown from SYT0113 treated 
seed, the field may be replanted immediately to canola, soybean, barley, oat, rye 
triticale and wheat. 
x Alfalfa, Brassica (Cole) leafy vegetables, buckwheat, corn, pearl millet, Proso 
millet, popcorn, rice (dry-seeded), sorghum, teosinte, wild rice, cotton, Cucurbit 
vegetables, dry bulb onions, fruiting vegetables, leafy vegetables, Legume 
vegetables, mint (peppermint and spearmint), oil seed crops (black mustard 
seed, borage seed, crambe seed, field mustard seed, flax seed, Indian mustard 
seed, Indian rapeseed seed, peanuts, rapeseed seed, and safflower seed), root 
vegetables, strawberry, sunflowers, tobacco, and tuberous and corm vegetables 
may be planted 30 days from the date the SYT0113 treated seed were planted. 
x For any other crop, the minimum plant-back interval is 120 days from the date 
the SYT0113 treated seed were planted. A cover crop other than the crops listed 
above that is planted for erosion control or soil improvement may be planted 
sooner than the 120-day interval; however, the crop may not be grazed or 
harvested for food or feed. 
x DO NOT apply more than 0.266 lb thiamethoxam per acre (120.6 g ai/A), 0.052 
lb mefenoxam or metalaxyl per acre (23 g ai/A), or 0.046 lb sedaxane per acre 
(19 g ai/A) per calendar year as a seed-treatment application. 
x This seed has been treated with 0.0756 mg ai thiamethoxam per seed. 
x DO NOT apply a neonicotinoid insecticide within 45 days of planting seed treated 
with SYT0113. 
x Groundwater Advisory: Thiamethoxam has properties and characteristics 
associated with chemicals detected in groundwater. This chemical may leach 
into the groundwater if used in areas where soils are permeable, particularly 
where the water table is shallow. Mefenoxam is known to leach through soil into 
groundwater under certain conditions as a result of agricultural use. Use of this 
chemical in areas where soils are permeable, particularly where the water table 
is shallow, may result in groundwater contamination. 
x Pollinator Precautions: Thiamethoxam is highly toxic to bees, and effects are 
possible as a result of exposure to translocated residues in blooming crops. 
x Advisory Dust-Reducing Technique: The use of seed flow lubricants or 
polymer coatings may help decrease the amount of dust released during 
planting. Follow the recommendations of the planter manufacturer regarding the 
use of seed flow lubricants. 
x [All seed bag tags must be legible and set in at least 8-point font size.]

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CROP USE DIRECTIONS 
 
When applied according to the SYT0113 RATE TABLE, SYT0113 provides early 
season protection against injury by aphids, bean leaf beetle, grape colaspis, leaf 
miners, leaf hoppers, Mexican bean beetle, seed corn maggot, threecornered alfalfa 
hopper, thrips, white grubs, and wireworm. 
 
SYT0113 provides protection against damping-off and seed borne rots due to Pythium, 
Phytophthora, Fusarium, Rhizoctonia species and early season Phytophthora root rot. 
SYT0113 also suppresses seed-borne Sclerotinia and Phomopsis species. 
 
SYT0113 RATE TABLE
1 
 
 
Crop 
 
 
Rate of SYT0113 
 
Soybean, including 
soybean, vegetable 
 
fl oz per 
100 lb seed 
or 
fl oz per 140,000 
seeds 
 
grams ai per 
100 kg seed 
 
mg ai 
per seed 
 
3.38 fl oz 
or 
1.58 fl oz per 
140,000 seeds 
 
Thiamethoxam 50 gm 
 
Mefenoxam 15.0 gm 
 
Fludioxonil 2.5 gm 
 
Sedaxane 2.5 gm 
 
 
Thiamethoxam 0.0756 mg 
 
Mefenoxam 0.0226 mg 
 
Fludioxonil 0.0038 mg 
 
Sedaxane 0.0038 mg 
 
Total = 0.1058 mg 
 
 
1The mg ai per seed and fl oz SYT0113 per 100 lb seed and 140,000 seeds rates are based on 3,000 
seeds per pound. 
 
DO NOT apply more than 0.052 lb ai/Acre (23 g ai/Acre) per calendar year of 
mefenoxam- or metalaxyl-containing products as a seed treatment on Soybean 
(including soybean, vegetable). 
 
Stored Grain Protection 
 
When treated according to the directions for post-planting protection against listed 
pests, SYT0113 will also provide protection during post treatment storage of the 
soybean seed against damage from the following stored grain insects: Indian Meal 
Moth (Plodia interpunctella), Rice Weevil (Sitophilus oryza), Red Flour Beetle (Tribolium 
castaneum), and Lesser Grain Borer (Rhizopertha dominica).

14 
If the soybean seed to be treated has existing infestations of stored grain insects, 
fumigate the seed with a registered product approved for such use, prior to treating with 
SYT0113 and bagging. 
 
STORAGE AND DISPOSAL 
 
Do not contaminate water, food, or feed by storage or disposal. 
 
Pesticide Storage 
 
Store in a cool, dry place. Storage for extended periods above 90°F is not 
recommended. 
 
For minor spills, leaks, etc., follow all precautions indicated on this label and clean up 
immediately. Take special care to avoid contamination of equipment and facilities 
during cleanup procedures and disposal of wastes. 
 
Pesticide Disposal 
 
Wastes resulting from the use of this product may be disposed of on site or at an 
approved waste disposal facility. If these wastes cannot be used according to label 
instructions, contact your State Pesticide or Environmental Control Agency or the 
Hazardous Waste representative at the nearest EPA Regional Office for guidance in 
proper disposal methods. 
 
Container Handling [5 gallons or less] 
Non-refillable container. Do not reuse or refill this container. Triple rinse container (or 
equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining 
contents into application equipment or a mix tank. Drain for 10 seconds after the flow 
begins to drip. Fill the container ¼ full with water and recap. Shake for 10 seconds. 
Pour rinsate into application equipment or a mix tank or store rinsate for later use and 
disposal. Drain for 10 seconds after the flow begins to drip. Repeat this procedure two 
more times. Then offer for recycling if available or puncture and dispose of in a sanitary 
landfill, or by incineration, or by other procedures approved by state and local 
authorities. 
 
Container Handling [greater than 5 gallons] 
Non-refillable container. Do not reuse or refill this container. Triple rinse container (or 
equivalent) promptly after emptying. Triple rinse as follows: empty the remaining 
contents into application equipment or a mix tank and drain for 10 seconds after the flow 
begins to drip. Fill the container ¼ full with water. Replace and tighten closures. Tip 
container on its side and roll it back and forth, ensuring at least one complete revolution, 
for 30 seconds. Stand the container on its end and tip it back and forth several times. 
Turn the container over onto its other side and tip it back and forth several times. 
Empty the rinsate into application equipment or a mix tank or store rinsate for later use 
and disposal. Repeat this procedure two more times. Then offer for recycling if

15 
available or puncture and dispose of in a sanitary landfill, or by incineration, or by other 
procedures approved by state and local authorities. 
 
Container Handling [greater than 5 gallons] 
Refillable container. Refill this container with pesticide only. Do not reuse this 
container for any other purpose. Cleaning the container before final disposal is the 
responsibility of the person disposing of the container. Cleaning before refilling is the 
responsibility of the person refilling. To clean container before final disposal, empty the 
remaining contents from this container into application equipment or mix tank. Fill the 
container about 10 percent full with water. Agitate vigorously or re-circulate water with 
the pump for 2 minutes. Pour or pump rinsate into application equipment or rinsate 
collection system. Repeat this rinsing procedure two more times. Then offer for 
recycling if available or puncture and dispose of in a sanitary landfill, or by incineration, 
or by other procedures approved by state and local authorities. 
 
CONTAINER IS NOT SAFE FOR FOOD, FEED, OR DRINKING WATER! 
 
The ALLIANCE FRAME, the SYNGENTA Logo, and the PURPOSE ICON are 
Trademarks of a Syngenta Group Company 
 
Viton™ is a trademark of The Chemours Company FC, LLC 
 
© 20XX Syngenta 
 
For non-emergency (e.g., current product information), call 
Syngenta Crop Protection at 1-866-796-4368. 
 
Manufactured for: 
Syngenta Crop Protection, LLC 
P. O. Box 18300 
Greensboro, North Carolina 27419-8300 
 
 
SYT0113 1459 MAS 0919 AMEND-B 0226-CL – jeb – 05/21/2026 
000100-01459.20260216B.SYT0113.AMEND.FEB2026-CL.PDF