crop-chem-docs/corpus/epa_ppls/100-1559.md

# THX/MXM/FLD/TBZ/SDX FS

- EPA Reg No: **100-1559**
- Registrant: SYNGENTA CROP PROTECTION, LLC
- Signal word: Caution
- Active ingredients: Thiabendazole (2.24%); Thiamethoxam (22.4%); Fludioxonil (1.12%); Metalaxyl-M (3.35%); Sedaxane (1.12%)
- Label accepted: 2026-06-22
- Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000100-01559-20260622.pdf

---
June 22, 2026
Patsy Laird, Ricky Kyaw 
Regulatory Managers
Syngenta Crop Protection, LLC
P. O. Box 18300
Greensboro, NC 27419
Patsy.laird@syngeta.com, ricky.kyaw@syngetna.com
Subject: Label Amendment - Registration Review Mitigation for Sedaxane and 
Thiabendazole
Product Name: THX/MXM/FLD/TBZ/SDX FS
EPA Registration Number: 100-1559
Case Numbers: 684639 and 482813
Application Dates: February 13, 2026 and December 14, 2020
Dear Patsy Laird and Ricky Kyaw: 
The Agency, in accordance with the Federal Insecticide, Fungicide, and Rodenticide Act 
(FIFRA), as amended, has completed reviewing all the information submitted with your 
application to support the Registration Review of the above referenced product in 
connection with the sedaxane and thiabendazole Interim Decisions, and has concluded 
that your submission is acceptable. The label referred to above, submitted in connection 
with registration under FIFRA, as amended, is acceptable.
Should you wish to add/retain a reference to the company’s website on your label, then 
please be aware that the website becomes labeling under the Federal Insecticide, 
Fungicide, and Rodenticide Act and is subject to review by the Agency. If the website is
false or misleading, the product would be misbranded and unlawful to sell or distribute 
under FIFRA section 12(a)(1)(E). 40 CFR 156.10(a)(5) list examples of statements EPA may 
consider false or misleading. In addition, regardless of whether a website is referenced on 
your product’s label, claims made on the website may not substantially differ from those 
claims approved through the registration process. Therefore, should the Agency find or if it 
is brought to our attention that a website contains false or misleading statements or 
claims substantially differing from the EPA approved registration, the website will be 
referred to the EPA’s Office of Enforcement and Compliance Assurance.

Page 2 of 2 
EPA Reg. No. 100-1559 
Case No. 684639 and 482813 
 
A stamped copy of your labeling is enclosed for your records. This labeling 
supersedes all previously accepted labeling and must be used at your next label 
printing. You must submit one copy of the final printed labeling before you release 
the product for shipment with the new labeling. In accordance with 40 CFR 
152.130(c), you may distribute or sell this product under the previously approved 
labeling for 12 months from the date of this letter. After 12 months, you may only 
distribute or sell this product if it bears this new revised labeling or subsequently 
approved labeling. “To distribute or sell” is defined under FIFRA section 2(gg) and 
its implementing regulation at 40 CFR 152.3. 
 
If you have any questions about this letter, please contact Samantha Carter by phone at 
(202) 566-1179, or via email at carter.samantha@epa.gov. 
 
 S i n c e r e l y , 
 
 
 J a c l y n P y n e , T e a m L e a d e r 
 R i s k M a n a g e m e n t a n d I m p l e m e n t a t i o n B r a n c h 3 
 P e s t i c i d e R e - E v a l u a t i o n D i v i s i o n 
 O f f i c e o f P e s t i c i d e P r o g r a m s 
 
ENCLOSURE: Stamped label

THX/MXM/FLD/TBZ/SDX FS
Page 1
(MASTER)
THIAMETHOXAM GROUP 4A INSECTICIDE
THIABENDAZOLE GROUP 1 FUNGICIDE
MEFENOXAM GROUP 4 FUNGICIDE
SEDAXANE GROUP 7 FUNGICIDE
FLUDIOXONIL GROUP 12 FUNGICIDE
THX/MXM/FLD/TBZ/SDX FS
Insecticide with Fungicides
A seed treatment product for protection against damage from listed: insects, seed-borne 
diseases, and seedling diseases on soybean
Active Ingredients:
Thiamethoxam
1 ................................................................................................. 22.40%
Mefenoxam2 ........................................................................................................ 3.35%
Thiabendazole3 ................................................................................................... 2.24%
Fludioxonil4.......................................................................................................... 1.12%
Sedaxane5........................................................................................................... 1.12%
Other Ingredients: 69.77%
Total: 100.00%
1CAS No. 153719-23-4
2CAS No. 70630-17-0 and CAS No. 69516-34-3
3CAS No. 148-79-8
4CAS No. 131341-86-1
5CAS No. 874967-67-6
One gallon of THX/MXM/FLD/TBZ/SDX FS contains 2.16 lb thiamethoxam, 0.32 lb
mefenoxam, 0.22 Lb thiabendazole, 0.11 lb fludioxonil and 0.11 lb sedaxane.
KEEP OUT OF REACH OF CHILDREN.
CAUTION
See additional precautionary statements and directions for use in booklet [on label].
EPA Reg. No. 100-1559
EPA Est. 
_______________
Net Contents
06/22/2026
100-1559

THX/MXM/FLD/TBZ/SDX FS 
Page 2 
(MASTER) 
 
FIRST AID 
If swallowed x Call a poison control center or doctor immediately for treatment 
advice. 
x Have person sip a glass of water if able to swallow. 
x Do not induce vomiting unless told to by a poison control center 
or doctor. 
x Do not give anything to an unconscious person. 
Have the product container or label with you when calling a poison control center or 
doctor or going for treatment. 
HOTLINE NUMBER 
For 24-Hour Medical Emergency Assistance (Human or Animal) 
or Chemical Emergency Assistance (Spill, Leak, Fire, or Accident), 
Call 
1-800-888-8372 
 
PRECAUTIONARY STATEMENTS 
 
HAZARDS TO HUMANS AND DOMESTIC ANIMALS 
 
CAUTION 
 
Harmful if swallowed. Wash thoroughly with soap and water after handling, and before 
eating, drinking, chewing gum, using tobacco, or using the toilet. 
 
PERSONAL PROTECTIVE EQUIPMENT (PPE) 
 
Applicators and other handlers must wear: 
 
x Long-sleeved shirt and long pants. 
x Chemical-resistant gloves made of EDUULHUODPLQDWHEXW\OUXEEHU•PLOVQLWULOH
UXEEHU•PLOVQHRSUHQHUXEEHU•PLOVSRO\YLQ\OFKORULGH39&•PLOVRU
9LWRQ™ •PLOV 
x Shoes plus socks. 
 
Follow manufacturer’s instructions for cleaning/maintaining PPE. If no such instructions 
for washables exist, use detergent and hot water. Keep and wash PPE separately from 
other laundry. 
 
Engineering Controls 
 
When handlers use closed systems in a manner that meets the requirements listed in 
the Worker Protection Standard (WPS) for agricultural pesticides (40 CFR 170.607 (d) 
and (e)), the handler PPE requirements may be reduced or modified as specified in the 
WPS.

THX/MXM/FLD/TBZ/SDX FS 
Page 3 
(MASTER) 
 
 
USER SAFETY RECOMMENDATIONS 
 
Users should: 
 
x Wash hands before eating, drinking, chewing gum, using tobacco, or using the 
toilet. 
x Remove clothing/PPE immediately if pesticide gets inside. Then wash 
thoroughly and put on clean clothing. 
x Remove PPE immediately after handling this product. Wash the outside of 
gloves before removing. As soon as possible, wash thoroughly and change 
into clean clothing. 
 
ENVIRONMENTAL HAZARDS 
 
This product is toxic to wildlife, freshwater and estuarine/marine fish and highly toxic to 
aquatic invertebrates. Runoff may be hazardous to aquatic organisms in neighboring 
areas. Do not contaminate water when disposing of equipment washwater or rinsate. 
 
Pollinator Precautions 
 
Thiamethoxam is highly toxic to bees exposed to direct treatment, and effects may be 
possible as a result of exposure to translocated residues in blooming crops. 
 
Non-Target Organism Advisory Statement 
 
This product may adversely impact non-target organisms feeding on treated seed. 
Protect the non-target organisms by following label directions intended to minimize 
availability of treated seed to non-target organisms. 
 
Groundwater Advisory 
 
Thiamethoxam has properties and characteristics associated with chemicals detected in 
groundwater. This chemical may leach into the groundwater if used in areas where 
soils are permeable, particularly where the water table is shallow. 
Mefenoxam is known to leach through soil into groundwater under certain conditions as 
a result of label use. This chemical may leach into the groundwater if used in areas 
where soils are permeable, particularly where the water table is shallow. 
 
Physical and Chemical Hazards 
 
Do not use, pour, spill or store near heat or open flame. Do not store near or use with 
oxidizing agents.

THX/MXM/FLD/TBZ/SDX FS 
Page 4 
(MASTER) 
 
 
CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY 
 
NOTICE: Read the entire Directions for Use and Conditions of Sale and Limitation of 
Warranty and Liability before buying or using this product. If the terms are not acceptable, 
return the product at once, unopened, and the purchase price will be refunded. 
 
The Directions for Use of this product must be followed carefully. It is impossible to 
eliminate all risks inherently associated with the use of this product. Crop injury, 
ineffectiveness or other unintended consequences may result because of such factors as 
manner of use or application, weather or crop conditions, presence of other materials or 
other influencing factors in the use of the product, which are beyond the control of 
SYNGENTA CROP PROTECTION, LLC or Seller. To the extent permitted by applicable 
law, Buyer and User agree to hold SYNGENTA and Seller harmless for any claims 
relating to such factors. 
 
SYNGENTA warrants that this product conforms to the chemical description on the label 
and is reasonably fit for the purposes stated in the Directions for Use, subject to the 
inherent risks referred to above, when used in accordance with directions under normal 
use conditions. To the extent permitted by applicable law: (1) this warranty does not 
extend to the use of this product contrary to label instructions or under conditions not 
reasonably foreseeable to or beyond the control of Seller or SYNGENTA, and, (2) Buyer 
and User assume the risk of any such use. TO THE EXTENT PERMITTED BY 
APPLICABLE LAW, SYNGENTA MAKES NO WARRANTIES OF MERCHANTABILITY 
OR OF FITNESS FOR A PARTICULAR PURPOSE NOR ANY OTHER EXPRESS OR 
IMPLIED WARRANTY EXCEPT AS WARRANTED BY THIS LABEL. 
 
To the extent permitted by applicable law, in no event shall Syngenta be liable for any 
incidental, consequential or special damages resulting from the use or handling of this 
product. TO THE EXTENT PERMITTED BY APPLICABLE LAW, THE EXCLUSIVE 
REMEDY OF THE USER OR BUYER, AND THE EXCLUSIVE LIABILITY OF 
SYNGENTA AND SELLER FOR ANY AND A LL CLAIMS, LOSSES, INJURIES OR 
DAMAGES (INCLUDING CLAIMS BASED ON BREACH OF WARRANTY, 
CONTRACT, NEGLIGENCE, TORT, STRICT LIABILITY OR OTHERWISE) 
RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, SHALL BE THE 
RETURN OF THE PURCHASE PRICE OF THE PRODUCT OR, AT THE ELECTION OF 
SYNGENTA OR SELLER, THE REPLACEMENT OF THE PRODUCT. 
 
SYNGENTA and Seller offer this product, and Buyer and User accept it, subject to the 
foregoing Conditions of Sale and Limitation of Warranty and Liability, which may not be 
modified except by written agreement signed by a duly authorized representative of 
SYNGENTA.

THX/MXM/FLD/TBZ/SDX FS 
Page 5 
(MASTER) 
 
DIRECTIONS FOR USE 
 
It is a violation of federal law to use this product in a manner inconsistent with its 
labeling. 
 
For use in commercial seed treatment facilities. Use is also permitted as an end-use 
seed treatment on agricultural establishments at planting, or immediately before 
planting, as specified in the Specific Crop Use Directions. This product is to be used in 
liquid or slurry treaters only. 
 
Treatment of highly mechanically scarred or damaged seed or seed known to be of low 
vigor and poor quality may result in reduced germination and/or reduction of seed and 
seedling vigor. Treat a quantity of seed using equipment similar to that planned for 
treating the total seed lot. Prior to treatment, conduct germination tests on a portion of 
seed before committing the total seed lot to a selected seed treatment. 
 
Due to seed quality, crop or variety sensitivity, and seed storage conditions beyond the 
control of Syngenta, no claims are made to guarantee the germination of seed or 
propagating material for all crop seed when treated with THX/MXM/FLD/TBZ/SDX FS. 
 
Maximum usage when applying metalaxyl- and mefenoxam- containing products 
to the same crop within the same season: Do not apply more than the maximum 
yearly total application rate for the active ingredient as stated on the label of the product 
containing the lowest yearly total on that crop. 
 
FAILURE TO FOLLOW THE DIRECTIONS FOR USE AND PRECAUTIONS ON THIS 
LABEL MAY RESULT IN CROP INJURY, POOR INSECT AND/OR DISEASE 
CONTROL, AND/OR ILLEGAL RESIDUES. 
 
AGRICULTURAL USE REQUIREMENTS 
 
Use this product only in accordance with its labeling and with the Worker Protection 
Standard, 40 CFR part 170. This Standard contains requirements for the protection of 
agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of 
agricultural pesticides. It contains requirements for training, decontamination, 
notification, and emergency assistance. It also contains specific instructions and 
exceptions pertaining to the statements on this label about personal protective 
equipment (PPE) and restricted-entry interval. The requirements in this box only apply 
to uses of this product that are covered by the Worker Protection Standard. 
 
Do not enter or allow worker entry into treated areas during the restricted-entry 
interval (REI) of 48 hours. Exception: If the seed is treated with the product and the 
treated seed is soil-injected or soil-incorporated, the Worker Protection Standard, under 
certain circumstances, allows workers to enter the treated area if there will be no 
contact with anything that has been treated.

THX/MXM/FLD/TBZ/SDX FS 
Page 6 
(MASTER) 
 
PPE required for early entry to treated areas that is permitted under the Worker 
Protection Standard and that involves contact with anything that has been treated, such 
as plants, soil, or water is: 
 
x Coveralls 
x Chemical-resistant gloves made of EDUULHUODPLQDWHEXW\OUXEEHU•PLOVQLWULOH
UXEEHU•PLOVQHRSUHQHUXEEHU•PLOVSRO\YLQ\OFKORULGH39&•PLOVRU
9LWRQ•PLOV 
x Shoes plus socks 
 
 
PRODUCT INFORMATION 
 
THX/MXM/FLD/TBZ/SDX FS is a seed treatment product containing the active 
ingredients thiamethoxam (insecticide) and fludioxonil, thiabendazole, mefenoxam and 
sedaxane (fungicides). THX/MXM/FLD/TBZ/SDX FS protects against damage from 
listed early-season insects, soil-borne and seed-borne diseases of soybeans. 
 
Thiamethoxam is a systemic seed treatment insecticide belonging to the neonicotinoid 
class of chemistry. Thiamethoxam protects against listed chewing and sucking insects 
through contact and ingestion. 
 
Mefenoxam fungicide is active against Pythium, Phytophthora and systemic downy 
mildew. 
 
Thiabendazole fungicide is active for protection against phomopsis spp. to improve 
germination and early season seedling health. Thiabendazole also suppresses seed-
borne Sclerotinia and Phomopsis species. 
 
Fludioxonil fungicide is active against Fusarium and Rhizoctonia, and suppresses seed-
borne Sclerotinia and Phomopsis species. 
 
Sedaxane fungicide is active against seed decay, seedling blight and damping-off 
caused by Rhizoctonia species. 
 
 
RESISTANCE MANAGEMENT 
 
THIABENDAZOLE GROUP 1 FUNGICIDE 
MEFENOXAM GROUP 4 FUNGICIDE 
SEDAXANE GROUP 7 FUNGICIDE 
FLUDIOXONIL GROUP 12 FUNGICIDE 
 
Fungicide Resistance Management 
 
For resistance management, please note that THX-MXM/FDL/TBZ/SDX FS contains

THX/MXM/FLD/TBZ/SDX FS 
Page 7 
(MASTER) 
 
Group 1/ thiabendazole, Group 4/ mefenoxam, Group 7/sedaxane and Group 
12/fludioxonil fungicides. Any fungal population may contain individuals naturally 
resistant to THX-MXM/FDL/TBZ/SDX FS and other Group 1, Group 4, Group 7 or 
Group 12 fungicides. A gradual or total loss of pest control may occur over time if these 
fungicides are used repeatedly in the same fields. Appropriate resistance-management 
strategies should be followed. 
 
Thiabendazole belongs to the methyl-benzimidazole carbamate class of chemistry 
which disrupts ß-tubulin assembly in mitosis. Mefenoxam belongs to the phenylamide 
class of chemistry which interferes with fungal RNA synthesis. Sedaxane is a succinate 
dehydrogenase inhibitor (SDHI) and belongs to the carboxamide class of chemistry 
which disrupts cellular respiration and energy generation. Fludioxonil belongs to the 
phenylpyrrole class of chemistry which interferes with a MAP/histidine protein kinase in 
osmotic signal transduction. 
 
To delay fungicide resistance, take one or more of the following steps: 
x Rotate the use of THX-MXM/FDL/TBZ/SDX FS or other Group 1, Group 4, Group 7 
or Group 12 fungicides within a growing season sequence with different groups that 
control the same pathogens. 
x Use tank mixtures with fungicide from a different group that are equally effective on 
the target pest when such use is permitted. Use at least the minimum application 
rate as labeled by the manufacturer. 
x Adopt an integrated disease management program for fungicide use that includes 
scouting, uses historical information related to pesticide use, and crop rotation, and 
which considers host plant resistance, impact of environmental conditions on 
disease development, disease thresholds, as well as cultural, biological and other 
chemical control practices. 
x Where possible, make use of predictive disease models to effectively time fungicide 
applications. Note that using predictive models alone is not sufficient to manage 
resistance. 
x Monitor treated fungal populations for resistance development. 
x Contact your local extension specialist or certified crop advisor for any additional 
pesticide resistance-management and/or IPM recommendations for specific crop 
and pathogens. 
x For further information or to report suspected resistance contact Syngenta at 1-866-
Syngent(a) (866-796-4368). You can also contact your pesticide distributor or 
university extension specialist to report resistance. 
 
THIAMETHOXAM GROUP 
4A INSECTICIDE 
 
Insecticide Resistance Management 
 
For resistance management, THX/MXM/FLD/TBZ/SDX FS contains a Group 
4A/thiamethoxam insecticide. Any insect population may contain individuals naturally 
resistant to THX/MXM/FLD/TBZ/SDX FS and other Group 4A insecticides. The 
resistant individuals may dominate the insect population if this group of insecticides are

THX/MXM/FLD/TBZ/SDX FS 
Page 8 
(MASTER) 
 
used repeatedly in the same fields. Appropriate resistance-management strategies 
should be followed. 
 
Thiamethoxam is a systemic insecticide belonging to the neonicotinoid class of chemistry 
which includes nicotinic acetylcholine receptor (nAChR) agonists.
 
 
To delay insecticide resistance, take the following steps: 
x Rotate the use of THX/MXM/FLD/TBZ/SDX FS or other Group 4A insecticides 
within a growing season, or among growing seasons, with different groups that 
control the same pests. 
x Use tank mixtures with insecticides from a different group that are equally 
effective on the target pest when such use is permitted. Do not rely on the same 
mixture repeatedly for the same pest population. Consider any known cross-
resistance issues (for the targeted pests) between the individual components of a 
mixture. In addition, consider the following recommendations provided by the 
Insecticide Resistance Action Committee (IRAC): 
o Individual insecticides selected for use in mixtures should be highly 
effective and be applied at the rates at which they are individually 
registered for use against the target species. 
o Mixtures with components having the same IRAC mode of action 
classification are not recommended for insect resistance management. 
o When using mixtures, consider any known cross-resistance issues 
between the individual components for the targeted pest(s). 
o Mixtures become less effective if resistance is already developing to one 
or both active ingredients, but they may still provide pest management 
benefits. 
o The insect resistance management benefits of an insecticide mixture are 
greatest if the two components have similar periods of residual insecticidal 
activity. Mixtures of insecticides with unequal periods of residual 
insecticide activity may offer an insect resistance management benefit 
only for the period where both insecticides are active. 
x Adopt an integrated pest management program for insecticide/acaricides use 
that includes scouting, uses historical information related to pesticide use, crop 
rotation, record keeping, and which considers cultural, biological and other 
chemical control practices. 
x Monitor after application for unexpected target pest survival. If the level of 
survival suggests the presence of resistance, consult with your local university 
specialist or certified pest control advisor. 
x Contact your local extension specialist or certified crop advisors for any 
additional pesticide resistance-management and/or IPM recommendations for 
the specific site and pest problems in your area. 
x For further information or to report suspected resistance contact Syngenta at 1-
866-796-4368. 
 
Syngenta encourages responsible product stewardship to ensure effective long-term 
control of the insect and fungal diseases on this label.

THX/MXM/FLD/TBZ/SDX FS 
Page 9 
(MASTER)

THX/MXM/FLD/TBZ/SDX FS 
Page 10 
(MASTER) 
 
 
CROP ROTATIONAL RESTRICTIONS 
 
In the event of a crop failure or harvest of a crop grown from THX/MXM/FLD/TBZ/SDX 
FS treated seed, the field may be replanted according to the following schedule: 
 
Immediate Plantback Minimum 30-Day 
Plantback Interval 
Minimum 120-Day 
Plantback Interval 
Cereal Grains: Barley, Oats, 
Rye, Triticale, and Wheat 
Peas, Dried Shelled: 
Chickpea (Garbanzo Bean), 
Field Pea, Lentil, and 
Pigeon Pea 
Soybean 
Alfalfa 
Brassica &ROH/HDI\9HJHWDEOHV 
Cereal Grains (buckwheat, corn, 
pearl millet, proso, popcorn, rice 
(dry-seeded), sorghum, 
teosinite, wild rice) 
Cotton 
&XFXUELW9HJHWDEOHV 
)UXLWLQJ9HJHWDEOHV 
Globe Artichoke 
Leafy 9HJHWDEOHV 
/HJXPH9HJHWDEOHV (Succulent 
or Dried) 
Mint: Peppermint and Spearmint 
Oilseeds: Borage, Crambe, Flax 
Seed, Mustard Seed, and 
Safflower 
Peanut 
5RRW9HJHWDEOHV 
Strawberry 
Sunflower 
Tobacco 
All Other Crops 
For any other crop, the minimum plant back interval is 120 days from the date the 
THX/MXM/FLD/TBZ/SDX FS treated seed was planted. A cover crop other than the 
crops listed above that is planted for erosion control or soil improvement may be planted 
sooner than the 120-day interval; however, the crop may not be grazed or harvested for 
food or feed. 
 
 
MIXING PROCEDURES 
 
Important: Always re-circulate THX/MXM/FLD/TBZ/SDX FS thoroughly before using. 
 
Consult the manufacturer of the application equipment you plan to use for suitability for 
this application and for instructions on operation and calibration of the equipment. 
Follow the manufacturer application instructions for the seed treatment equipment being 
used. 
 
Required Dye Statement: Seed treated with this product must be visually identifiable 
from untreated seed by the use of an approved colorant or dye to prevent accidental 
use of treated seed as food for humans or feed for animals. Refer to 21 CFR, Part 2.25. 
Any colorant or dye added to treated seed must be cleared for use in accordance with 
40 CFR, Part 153.155(c).

THX/MXM/FLD/TBZ/SDX FS 
Page 11 
(MASTER) 
 
 
Apply THX/MXM/FLD/TBZ/SDX FS as a water-based slurry utilizing standard slurry or 
direct inject seed treatment equipment which provides uniform seed coverage. Uneven 
or incomplete seed coverage may not give the desired level of disease control. 
Thoroughly mix the specified amount of THX/MXM/FLD/TBZ/SDX FS into the required 
amount of water or liquid inoculant for the slurry treater and dilution rate to be used. For 
direct product inject systems, add the required amount of water or liquid inoculant 
during application. 
 
Certain crops require addition of inoculants when the seed is treated or planted. 
THX/MXM/FLD/TBZ/SDX FS is compatible with several liquid inoculant products. 
Consult the maker of the inoculant product and a Syngenta representative for directions 
before applying THX/MXM/FLD/TBZ/SDX FS with inoculants. 
 
The total application volume must be sufficient to provide desired level of coverage. 
Dilution is typically done with water or liquid inoculants. The minimum slurry volume to 
achieve minimum adequate coverage is 4.0 fluid ounces per 100 pounds of seed 
assuming an average seed size of 3,000 seeds per pound (slurry volume will vary 
depending on seed size). More diluent may be required to obtain complete coverage. 
 
Continuous agitation or mixing of the slurry mixture is necessary to prevent settling out 
of the solution. 
 
Allow seed to dry before bagging or reprocessing directly after treating operation. 
 
Follow planter manufacturer specifications for use of talc or other hopper box additives 
at planting. Seed must be completely dry before adding to planter. 
 
 
SEED BAG LABEL REQUIREMENTS 
 
Use of On-Farm Treated Seed (when treated seed are not for sale or distribution) 
Treated seed sold or distributed for a use not permitted by the following labeling does 
not qualify as an exempted treated article under 40 CFR 152.25(a) and is therefore sale 
or distribution of an unregistered pesticide, pursuant to FIFRA section 12. 
 
x Store treated seed away from food and feedstuffs. 
x DO NOT allow children, pets, or livestock to have access to treated seed. 
x Treated seed are for planting purposes only. DO NOT use for food, feed, or oil 
purposes. DO NOT use treated seed for fuel or ethanol production purposes. 
x Wear long-sleeved shirt, long pants, sh oes, socks, and chemical-resistant gloves 
when handling treated seed. 
x DO NOT plant treated seed by broadcasting to the soil surface. Ensure that all 
planted seeds are thoroughly incorporated by the planter during planting. Additional 
incorporation may be required to thoroughly cover exposed seeds.

THX/MXM/FLD/TBZ/SDX FS 
Page 12 
(MASTER) 
 
x Treated seed exposed on the soil surface may be hazardous to wildlife. Cover or 
collect treated seed spilled during loading and planting (such as in row ends). 
x Treated seed must be planted into the soil at a depth greater than 1 inch. 
x Manage excess treated seed (e.g., spilled, unused, or expired treated seed) by one 
or more of the following methods: 
o Collect excess treated seed for reuse for planting. 
o Bury excess treated seed (only allowed if totaling 1 pound or less) at least 30 feet 
away from bodies of water at a depth of 6 inches or double the planting depth, 
whichever is greater. 
o Dispose of excess treated seed by placing them in a landfill in accordance with 
applicable laws in your state. 
o Return excess treated seed to the supplier if permitted by the state. 
x DO NOT contaminate bodies of water when disposing of equipment wash water. 
x Advisory Dust-Reducing Technique: The use of seed flow lubricants or polymer 
coatings may help decrease the amount of dust released during planting. Follow the 
recommendations of the planter manufacturer regarding the use of seed flow 
lubricants. 
 
Seed Treatment in Commercial Facilities or Seed Treatment on farm (when 
treated seed are to be sold or distributed) – Seed Bag Labeling Requirements 
 
The Federal Seed Act requires that bags containing treated seed shall be labeled with 
the following statements: 
x This seed has been treated with thiamethoxam insecticide and fludioxonil, 
mefenoxam, sedaxane, and thiabendazole fungicides. 
x DO NOT use for food, feed, or oil purposes. 
 
The U.S. Environmental Protection Agency requires that bags containing treated seed 
shall be labeled with the following statements. Any seed treated with 
THX/MXM/FLD/TBZ/SDX FS that is sold or distributed without these statements or that 
is sold or distributed for a use not permitted by the following labeling does not qualify as 
an exempted treated article under 40 CFR 152.25(a) and is therefore sale or distribution 
of an unregistered pesticide, pursuant to FIFRA section 12(a)(1)(A). 
 
This seed has been treated with THX/MXM/FLD/TBZ/SDX FS (EPA Reg No. 100-1559) 
containing fludioxonil, mefenoxam, sedaxane, thiabendazole, and thiamethoxam. Any 
seed treated with THX/MXM/FLD/TBZ/SDX FS that is sold or distributed for a use not 
permitted by the following labeling does not qualify as an exempted treated article under 
40 CFR 152.25(a) and is therefore sale or distribution of an unregistered pesticide, 
pursuant to FIFRA section 12(a)(1)(A). 
 
x The contents of this bag are for planting purposes only. DO NOT use for food, 
feed, or oil purposes. DO NOT use for fuel or ethanol production purposes. 
x Store treated seed away from food and feedstuffs. 
x DO NOT allow children, pets, or livestock to have access to treated seed.

THX/MXM/FLD/TBZ/SDX FS 
Page 13 
(MASTER) 
 
x Wear long-sleeved shirt, long pants and chemical-resistant gloves when handling 
treated seed. 
x DO NOT plant treated seed by broadcasting to the soil surface. Ensure that all 
planted seeds are thoroughly incorporated by the planter during planting. 
Additional incorporation may be required to thoroughly cover exposed seeds. 
x Treated seed exposed on soil surface may be hazardous to wildlife. Cover or 
collect treated seed spilled during loading and planting (such as in row ends). 
x Treated seed must be planted into the soil at a depth greater than 1 inch. 
x Manage excess treated seed (e.g., spilled, unused, or expired treated seed) by 
one or more of the following methods: 
o Collect excess treated seed for reuse for planting. 
o Bury excess treated seed (only allowed if totaling 1 pound or less) at least 30 
feet away from bodies of water at a depth of 6 inches or double the planting 
depth, whichever is greater. 
o Dispose of excess treated seed by placing them in a landfill in accordance 
with applicable laws in your state. 
o Return excess treated seed to the supplier if permitted by the state. 
x DO NOT contaminate water bodies when disposing of planting equipment wash 
waters. 
x Dispose of seed packaging in accordance with local requirements. 
x DO NOT graze or feed livestock on treated areas for 45 days after planting seed 
treated with THX/MXM/FLD/TBZ/SDX FS. 
x In the event of a crop failure or harvest of a crop grown from 
THX/MXM/FLD/TBZ/SDX FS treated seed, the field may be replanted according 
to the following schedule. 
Immediate Plantback Minimum 30-Day 
Plantback Interval 
Minimum 120-Day 
Plantback Interval 
Cereal Grains: Barley, 
Oats, Rye, Triticale, 
and Wheat 
Peas, Dried Shelled: 
Chickpea (Garbanzo 
Bean), Field Pea, 
Lentil, and Pigeon Pea 
Soybean 
Alfalfa 
Brassica &ROH/HDI\9HJHWDEOHV 
Cereal Grains (buckwheat, corn, 
pearl millet, proso, popcorn, rice 
(dry-seeded), sorghum, 
teosinite, wild rice) 
Cotton 
&XFXUELW9HJHWDEOHV 
)UXLWLQJ9HJHWDEOHV 
Globe Artichoke 
Leafy 9HJHWDEOHV 
/HJXPH9HJHWDEOHV6XFFXOHQW
or Dried) 
Mint: Peppermint and Spearmint 
Oilseeds: Borage, Crambe, Flax 
Seed, Mustard Seed, and 
Safflower 
Peanut 
5RRW9HJHWDEOHV 
Strawberry 
Sunflower 
Tobacco 
All Other Crops

THX/MXM/FLD/TBZ/SDX FS 
Page 14 
(MASTER) 
 
x For any other crop, the minimum plant back interval is 120 days from the date the 
THX/MXM/FLD/TBZ/SDX FS treated seed was planted. A cover crop other than 
the crops listed above that is planted for erosion control or soil improvement may 
be planted sooner than the 120-day interval; however, the crop may not be 
grazed or harvested for food or feed. 
x DO NOT apply more than 0.083 lb/A (37.8 g ai/A) thiamethoxam, 0.004 lb/A (2.0 
g ai/A) fludioxonil, and 0.013 lb/A (5.7 g ai/A) mefenoxam per calendar year as a 
seed treatment application. 
x This seed has been treated with 0.0756 mg ai thiamethoxam, 0.0113 mg 
mefenoxam, and 0.0038 mg fludioxonil per seed. 
x DO NOT use more than 0.266 lb ai/A of thiamethoxam per calendar year, 
including all thiamethoxam products and application methods (for example, seed 
treatment, in-furrow, and foliar). 
x DO NOT apply a neonicotinoid insecticide within 45 days of planting seed treated 
with THX/MXM/FLD/TBZ/SDX FS. 
x Non-Target Organism Advisory Statement: 
This product may adversely impact non-target organisms feeding on treated 
seed. Protect the non-target organisms by following label directions intended to 
minimize availability of treated seed to non-target organisms. 
x Groundwater Advisory: Mefenoxam is known to leach through soil into 
groundwater under certain conditions as a result of agricultural use. 
Thiamethoxam has properties and characteristics associated with chemicals 
detected in groundwater. These chemicals may leach into the groundwater if 
used in areas where soils are permeable, particularly where the water table is 
shallow. 
x Pollinator Precautions: Thiamethoxam is highly toxic to bees, and effects are 
possible as a result of exposure to translocated residues in blooming crops. 
x Advisory Dust-Reducing Technique: The use of seed flow lubricants or 
polymer coatings may help decrease the amount of dust released during 
planting. Follow the recommendations of the planter manufacturer regarding the 
use of seed flow lubricants. 
x [All seed bag tags must be legible and set in at least 8-point font size.] 
 
USE DIRECTIONS 
 
When applied according to the THX/MXM/FLD/TBZ/SDX FS RATE TABLE, 
THX/MXM/FLD/TBZ/SDX FS provides early season protection against injury by aphids, 
bean leaf beetle, grape colaspis, leaf miners, leaf hoppers, Mexican bean beetle, seed 
corn maggot, three-cornered alfalfa hopper, thrips, white grubs, and wireworm. 
 
THX/MXM/FLD/TBZ/SDX FS provides protection against damping-off and seed borne 
rots due to Pythium, Phytophthora, Fusarium, Rhizoctonia species and early season 
Phytophthora root rot. THX/MXM/FLD/TBZ/SDX FS also suppresses seed-borne 
Sclerotinia and Phomopsis species.

THX/MXM/FLD/TBZ/SDX FS 
Page 15 
(MASTER) 
 
THX/MXM/FLD/TBZ/SDX FS Rate Table1 
 
Crop Rate of THX/MXM/FLD/TBZ/SDX FS 
Soybean, including 
soybean, vegetable 
fl oz per 100 lb seed 
or 
fl oz per 140,000 seeds 
grams ai per 
100 kg seed 
mg ai 
per seed2 
2.96 fl oz 
or 
1.38 fl oz per 140,000 seeds 
Thiamethoxam 50 g 
Mefenoxam 7.5 g 
Thiabendazole 5.0 g 
Fludioxonil 2.5 g 
Sedaxane 2.5 g 
 
Total = 0.102 
 
1The mg ai per seed and fl oz THX/MXM/FLD/TBZ/SDX FS per 100 lb seed rates are based on 3,000 
seeds per pound. 
2This seed has been treated with 0.0756 mg ai/seed of thiamethoxam, 0.0113 mg ai/seed of mefenoxam, 
0.0076 mg ai/seed of thiabendazole, 0.0038 mg ai/seed of fludioxonil, and 0.0038 mg ai/seed of 
sedaxane.

THX/MXM/FLD/TBZ/SDX FS 
Page 16 
(MASTER) 
 
USE RESTRICTIONS 
x DO NOT allow children, pets, or livestock to have access to treated seed. 
x DO NOT graze or feed livestock on treated areas for 45 days after planting seed 
treated with THX/MXM/FLD/TBZ/SDX FS. 
x DO NOT apply more than 0.083 lb/A (37.8 g ai/A) thiamethoxam, 0.004 lb/A (2.0 
g ai/A) fludioxonil, and 0.013 lb/A (5.7 g ai/A) mefenoxam per calendar year as a 
seed treatment application. 
x This seed has been treated with 0.0756 mg ai thiamethoxam, 0.0113 mg 
mefenoxam, and 0.0038 mg fludioxonil per seed. 
x DO NOT use more than 0.266 lb ai/A of thiamethoxam per calendar year, 
including all thiamethoxam products and application methods (for example, seed 
treatment, in-furrow, and foliar). 
x DO NOT apply a neonicotinoid insecticide within 45 days of planting seed treated 
with THX/MXM/FLD/TBZ/SDX FS. 
 
STORED GRAIN PROTECTION 
 
When treated according to the directions for post-planting protection against listed 
pests, THX/MXM/FLD/TBZ/SDX FS will also provide protection during post treatment 
storage of the soybean seed against damage from the following stored grain insects: 
Indian Meal Moth (Plodia interpunctella), Rice Weevil (Sitophilus oryza), Red Flour 
Beetle (Tribolium castaneum), and Lesser Grain Borer (Rhizopertha dominica). 
 
If the soybean seed to be treated has existing infestations of stored grain insects, 
fumigate the seed with a registered product approved for such use prior to treating with 
THX/MXM/FLD/TBZ/SDX FS and bagging. 
 
STORAGE AND DISPOSAL 
 
Do not contaminate water, food, or feed by storage, or disposal, or cleaning of 
equipment. 
 
Pesticide Storage 
Store in a cool, dry place. Storage for extended periods above 90°F is not 
recommended. 
 
For minor spills, leaks, etc., follow all precautions indicated on this label and clean up 
immediately. Take special care to avoid contamination of equipment and facilities 
during cleanup procedures and disposal of wastes. 
 
Pesticide Disposal 
Wastes resulting from the use of this product may be disposed of on site or at an 
approved waste disposal facility. If these wastes cannot be used according to label 
instructions, contact your State Pesticide or Environmental Control Agency or the 
Hazardous Waste representative at the nearest EPA Regional Office for guidance in 
proper disposal methods.

THX/MXM/FLD/TBZ/SDX FS 
Page 17 
(MASTER) 
 
 
 
Container Handling [less than or equal to 5 gallons] 
Non-refillable container. Do not reuse or refill this container. Triple rinse container (or 
equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining 
contents into application equipment or a mix tank and drain for 10 seconds after the flow 
begins to drip. Fill the container ¼ full with water and recap. Shake for 10 seconds. 
Pour rinsate into application equipment or a mix tank or store rinsate for later use or 
disposal. Drain for 10 seconds after the flow begins to drip. Repeat this procedure two 
more times. Then offer for recycling if available or puncture and dispose of in a sanitary 
landfill, or by incineration, or by other procedures approved by state and local 
authorities. 
 
Container Handling [greater than 5 gallons] 
Non-refillable container. Do not reuse or refill this container. Triple rinse container (or 
equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining 
contents into application equipment or a mix tank. Fill the container ¼ full with water. 
Replace and tighten closures. Tip container on its side and roll it back and forth, 
ensuring at least one complete revolution, for 30 seconds. Stand the container on its 
end and tip it back and forth several times. Turn the container over onto its other end 
and tip it back and forth several times. Empty the rinsate into application equipment or 
a mix tank or store rinsate for later use or disposal. Repeat this procedure two more 
times. Then offer for recycling if available or puncture and dispose of in a sanitary 
landfill, or by incineration, or by other procedures approved by state and local 
authorities. 
 
Refillable container. Refill this container with pesticide only. Do not reuse this 
container for any other purpose. Cleaning the container before final disposal is the 
responsibility of the person disposing of the container. Cleaning before refilling is the 
responsibility of the person refilling. To clean container before final disposal, empty the 
remaining contents from this container into application equipment or mix tank. Fill the 
container about 10 percent full with water. Agitate vigorously or recirculate water with 
the pump for 2 minutes. Pour or pump rinsate into application equipment or rinsate 
collection system. Repeat this rinsing procedure two more times. Then offer for 
recycling if available or puncture and dispose of in a sanitary landfill, or by incineration, 
or by other procedures approved by state and local authorities. 
 
CONTAINER IS NOT SAFE FOR FOOD, FEED, OR DRINKING WATER! 
 
The ALLIANCE FRAME, the SYNGENTA Logo, and the PURPOSE ICON are 
Trademarks of a Syngenta Group Company 
 
9LWRQ™ is a trademark of The Chemours Company FC, LLC 
 
© 20XX Syngenta

THX/MXM/FLD/TBZ/SDX FS 
Page 18 
(MASTER) 
 
Manufactured for: 
Syngenta Crop Protection, LLC 
P. O. Box 18300 
Greensboro, North Carolina 27419-8300 
 
 
 
THX-MXM-FLD-TBZ-SDX FS 1559 MAS 0919 AMEND-B FEB2026-CL – jeb 05/21/2026 
000100-01559.20260216B.THX_MXM_FLD_TBZ_SDX_FS.AMEND.0226-CL.PDF