crop-chem-docs/corpus/epa_ppls/100-1690.md

# CruiserMaxx(R) APX

- EPA Reg No: **100-1690**
- Registrant: SYNGENTA CROP PROTECTION, LLC
- Signal word: Caution
- Active ingredients: Picarbutrazox (0.82%); Thiamethoxam (16.3%); Fludioxonil (0.82%); Metalaxyl-M (2.45%); Sedaxane (0.82%)
- Label accepted: 2026-08-12
- Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000100-01690-20260812.pdf

---
August 12, 2026
Patsy Laird
Regulatory Manager, Seedcare
Syngenta Crop Protection, LLC
P.O. Box 18300
Greensboro, NC 27419
Subject: Label Amendment - Registration Review Mitigation for Sedaxane
 Product Name: CruiserMaxx® APX
EPA Registration Number: 100-1690
 Application Date: February 13, 2026
Case Number: 685012
Dear Mrs. Patsy Laird:
The Agency, in accordance with the Federal Insecticide, Fungicide, and Rodenticide Act 
(FIFRA), as amended, has completed reviewing all the information submitted with your 
application to support the Registration Review of the above referenced product in 
connection with the Sedaxane Interim Decision, and has concluded that your submission 
is acceptable. The label referred to above, submitted in connection with registration under 
FIFRA, as amended, is acceptable.
Should you wish to add/retain a reference to the company’s website on your label, then 
please be aware that the website becomes labeling under the Federal Insecticide, 
Fungicide, and Rodenticide Act and is subject to review by the Agency. If the website is 
false or misleading, the product would be misbranded and unlawful to sell or distribute 
under FIFRA section 12(a)(1)(E). 40 CFR 156.10(a)(5) list examples of statements EPA may 
consider false or misleading. In addition, regardless of whether a website is referenced on 
your product’s label, claims made on the website may not substantially differ from those 
claims approved through the registration process. Therefore, should the Agency find or if it 
is brought to our attention that a website contains false or misleading statements or 
claims substantially differing from the EPA approved registration, the website will be 
referred to the EPA’s Office of Enforcement and Compliance Assurance.

Page 2 of 2
EPA Reg. No. 100-1690
Decision No. 685012
A stamped copy of your labeling is enclosed for your records. This labeling 
supersedes all previously accepted labeling and must be used at your next label 
printing. You must submit one copy of the final printed labeling before you release 
the product for shipment with the new labeling. In accordance with 40 CFR 
152.130(c), you may distribute or sell this product under the previously approved 
labeling for 12 months from the date of this letter. After 12 months, you may only 
distribute or sell this product if it bears this new revised labeling or subsequently 
approved labeling. “To distribute or sell” is defined under FIFRA section 2(gg) and 
its implementing regulation at 40 CFR 152.3.
If you have any questions about this letter, please contact Samantha Carter by phone at 
202-566-1179, or via email at carter.samantha@epa.gov. 
Sincerely,
Jaclyn Pyne, Team Leader
Risk Management and Implementation Branch 3
Pesticide Re-Evaluation Division
Office of Pesticide Programs
ENCLOSURE: Stamped label

CruiserMaxx APX
Page 1
(Master label)
THIAMETHOXAM GROUP 4A INSECTICIDE
MEFENOXAM GROUP 4 FUNGICIDE
SEDAXANE GROUP 7 FUNGICIDE
FLUDIOXONIL GROUP 12 FUNGICIDE
PICARBUTRAZOX GROUP U17 FUNGICIDE
CruiserMaxx® APX
[Alternate Brand Names: CruiserMaxx APX Uncolored, Golden Harvest Preferred Seed 
Treatment, Golden Harvest Preferred Seed Treatment CMX APX Series]
Engineered Fungicide-Insecticide Premix
A seed treatment product for protection against early-season damage from listed insects, 
seed-borne diseases, and seedling diseases on soybean.
Active Ingredients:
Thiamethoxam
1 .....................................................................................................16.30%
Mefenoxam2 ............................................................................................................2.45%
Picarbutrazox3 .........................................................................................................0.82%
Fludioxonil4 ..............................................................................................................0.82%
Sedaxane5 ...............................................................................................................0.82%
Other Ingredients: 78.79%
Total: 100.00%
1CAS No. 153719-23-4
2CAS No. 70630-17-0 and CAS No. 69516-34-3
3CAS No. 500207-04-5
4CAS No. 131341-86-1
5CAS No. 874967-67-6
CruiserMaxx APX is a flowable concentrate for seed treatment containing 1.52 lb 
thiamethoxam, 0.23 lb mefenoxam, 0.08 lb picarbutrazox, 0.08 lb fludioxonil and 0.08 lb 
sedaxane per gallon.
KEEP OUT OF REACH OF CHILDREN.
CAUTION
See additional precautionary statements and directions for use in booklet.
EPA Reg. No. 100-1690
EPA Est. No. 
-----------------
Net Contents
[Batch Code: _____ ] (For nonrefillables only.)
Aug 12, 2026
100-1690

CruiserMaxx APX 
Page 2 
TABLE OF CONTENTS 
 
1.0 FIRST AID 
2.0 PRECAUTIONARY STATEMENTS 
2.1 Hazards to Humans and Domestic Animals 
2.2 Personal Protective Equipment (PPE) 
2.3 User Safety Requirements 
2.4 Engineering Controls 
2.5 User Safety Recommendations 
2.6 Environmental Hazards 
2.6.1 Groundwater Advisory 
2.6.2 Pollinator Precautions 
2.7 Physical or Chemical Hazards 
DIRECTIONS FOR USE 
3.0 PRODUCT INFORMATION 
3.1 Resistance Management 
4.0 APPLICATION DIRECTIONS 
4.1 Mixing Directions 
4.1.1 Tank-Mix Precautions 
4.1.2 Tank-Mix Compatibility 
5.0 ROTATIONAL CROP RESTRICTIONS 
6.0 RESTRICTIONS AND PRECAUTIONS 
6.1 Use Restrictions 
7.0 SEED CONTAINER LABEL REQUIREMENTS 
7.1 Use of On-Farm Treated Seed (when treated seed are not for sale or distribution) 
7.2 Seed Treatment in Commercial Facilities or Seed Treatment On-Farm (when treated 
seed are to be sold or distributed) – Seed Bag Labeling Requirements 
8.0 CROP USE DIRECTIONS 
8.1 Soybean 
9.0 STORAGE AND DISPOSAL 
10.0 CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY

CruiserMaxx APX 
Page 3 
1.0 FIRST AID 
FIRST AID 
If swallowed x Call a poison control center or doctor immediately for treatment 
advice. 
x Have person sip a glass of water if able to swallow. 
x Do not induce vomiting unless told to do so by a poison control 
center or doctor. 
x Do not give anything by mouth to an unconscious person. 
If on skin or 
clothing 
x Take off contaminated clothing. 
x Rinse skin immediately with plenty of water for 15-20 minutes. 
x Call a poison control center or doctor for treatment advice. 
Have the product container or label with you when calling a poison control center or 
doctor, or going for treatment. 
HOTLINE NUMBER 
For 24-Hour Medical Emergency Assistance (Human or Animal) 
or Chemical Emergency Assistance (Spill, Leak, Fire, or Accident), 
Call 
1-800-888-8372 
 
2.0 PRECAUTIONARY STATEMENTS 
 
2.1 Hazards to Humans and Domestic Animals 
CAUTION 
 
Harmful if swallowed or absorbed through the skin. Avoid contact with skin, eyes or 
clothing. Remove and wash contaminated clothing before reuse. Wash thoroughly with 
soap and water after handling and before eating, drinking, chewing gum, using tobacco 
or using the toilet. 
 
2.2 Personal Protective Equipment (PPE) 
Applicators and other handlers must wear: 
 
x Long-sleeved shirt and long pants 
x Chemical-resistant gloves made of: EDUULHUODPLQDWHEXW\OUXEEHU•PLOVQLWULOHUXEEHU
•PLOVQHRSUHQHUXEEHU•PLOVSRO\YLQ\OFKORULGH39&•PLOV9LWRQ™ •PLOV 
x Shoes plus socks 
 
2.3 User Safety Requirements 
Follow the manufacturer’s instructions for cleaning/maintaining PPE. If no such instructions 
for washables exist, use detergent and hot water. Keep and wash PPE separately from other 
laundry.

CruiserMaxx APX 
Page 4 
 
2.4 Engineering Controls 
When handlers use closed systems in a manner that meets the requirements listed in the 
Worker Protection Standard (WPS) for agricultural pesticides (40 CFR 170.607 (d) and (e)), 
the handler PPE requirements may be reduced or modified as specified in the WPS. 
 
2.5 User Safety Recommendations 
Users should: 
x Wash hands before eating, drinking, chewing gum, using tobacco, or using the toilet. 
x Remove clothing/PPE immediately if pesticide gets inside. Then wash thoroughly 
and put on clean clothing. 
x Remove PPE immediately after handling this product. Wash the outside of gloves 
before removing. As soon as possible, wash thoroughly and change into clean 
clothing. 
 
2.6 Environmental Hazards 
This product is toxic to wildlife, freshwater and estuarine/marine fish, oysters, and shrimp and 
highly toxic to aquatic invertebrates. Runoff may be hazardous to aquatic organisms in 
neighboring areas. Exposed treated seed may be hazardous to wildlife. Cover or collect 
treated seed spilled during loading and planting. DO NOT contaminate water when 
disposing of equipment washwater or rinsate. 
 
2.6.1 Groundwater Advisory 
Mefenoxam is known to leach through soil into groundwater under certain conditions as a 
result of label use. This chemical may leach into groundwater if used in areas where soils 
are permeable, particularly where the water table is shallow, and may result in groundwater 
contamination. 
Fludioxonil has properties and characteristics associated with chemicals detected in 
groundwater. This chemical may leach into groundwater if used in areas where soils are 
permeable, particularly where the water table is shallow, and may result in groundwater 
contamination. 
Thiamethoxam has properties and characteristics associated with chemicals detected in 
groundwater. This chemical may leach into groundwater if used in areas where soils are 
permeable, particularly where the water table is shallow, and may result in groundwater 
contamination. 
2.6.2 Pollinator Precautions 
Thiamethoxam is highly toxic to bees and other pollinating insects, and effects are possible 
as a result of exposure to translocated residues in blooming crops.

CruiserMaxx APX 
Page 5 
2.7 Physical or Chemical Hazards 
DO NOT use, pour, spill or store near heat or open flame. DO NOT store near or use with 
oxidizing agents. DO NOT mix or allow coming in contact with oxidizing agents. Hazardous 
chemical reaction may occur. 
DIRECTIONS FOR USE 
 
It is a violation of federal law to use this product in a manner inconsistent with its labeling. 
For use in commercial seed treatment facilities. Use is also permitted as an end-use seed 
treatment on agricultural establishments at planting, or immediately before planting, as 
specified in the Crop Use Directions. DO NOT apply this product in a way that will contact 
workers or other persons, either directly or through drift. Only protected handlers may be in 
the area during application. For any requirements specific to your State or Tribe, consult the 
State or Tribal agency responsible for pesticide regulation. DO NOT use for at-plant 
applications (including hopper box, planter box, etc.). This product is to be used in liquid or 
slurry treaters only. 
FAILURE TO FOLLOW THE DIRECTIONS FOR USE AND PRECAUTIONS ON THIS 
LABEL MAY RESULT IN CROP INJURY, POOR INSECT AND/OR DISEASE CONTROL, 
AND/OR ILLEGAL RESIDUES. 
 
AGRICULTURAL USE REQUIREMENTS 
 
Use this product only in accordance with its labeling and with the Worker Protection 
Standard, 40 CFR part 170. This Standard contains requirements for the protection of 
agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of 
agricultural pesticides. It contains requirements for training, decontamination, notification, 
and emergency assistance. It also contains specific instructions and exceptions pertaining 
to the statements on this label about personal protective equipment (PPE) and restricted-
entry interval. The requirements in this box only apply to uses of this product that are 
covered by the Worker Protection Standard. 
 
DO NOT enter or allow worker entry into treated areas during the restricted-entry 
interval (REI) of 48 hours. Exception: If the seed is treated with the product and the 
treated seed is soil-injected or soil-incorporated, the Worker Protection Standard, under 
certain circumstances, allows workers to enter the treated area if there will be no contact 
with anything that has been treated. 
 
PPE required for early entry to treated areas that is permitted under the Worker Protection 
Standard and that involves contact with anything that has been treated, such as plants, 
soil, or water is: 
 
x Coveralls 
x Chemical-resistant gloves: EDUULHUODPLQDWHEXW\OUXEEHU•PLOVQLWULOHUXEEHU•
PLOVQHRSUHQHUXEEHU•PLOVSRO\YLQ\OFKORULGH39&•PLOV9LWRQ•PLOV 
x Shoes plus socks

CruiserMaxx APX 
Page 6 
 
Treatment of highly mechanically scarred or damaged seed or seed known to be of low vigor 
and poor quality may result in reduced germination and/or reduction of seed and seedling 
vigor. Treat a quantity of seed using equipment similar to that planned for treating the total 
seed lot. Prior to treatment, conduct germination tests on a portion of seed before committing 
the total seed lot to a selected seed treatment. 
Due to seed quality, crop or variety sensitivity, and seed storage conditions beyond the 
control of Syngenta, no claims are made to guarantee the germination of seed or propagating 
material for all crop seed when treated with CruiserMaxx APX. 
 
 
3.0 PRODUCT INFORMATION 
CruiserMaxx APX is a seed treatment product containing the active ingredients 
thiamethoxam (insecticide) and fludioxonil, mefenoxam, picarbutrazox and sedaxane 
(fungicides). CruiserMaxx APX protects against damage from listed early-season insects, 
soil-borne and seed-borne diseases. 
Thiamethoxam is a systemic seed treatment insecticide belonging to the neonicotinoid class 
of chemistry. Thiamethoxam protects against listed chewing and sucking insects through 
contact and ingestion. 
Mefenoxam fungicide is active against Pythium, Phytophthora and systemic downy mildew. 
Picarbutrazox fungicide is active against Pythium and Phytophthora causing seed rot and 
damping-off. 
Fludioxonil fungicide is active against Fusarium and Rhizoctonia, and suppresses seed-borne 
Sclerotinia as well as provides protection from seed-borne Diaporthe-Phomopsis disease 
complex sometimes referred to as pod and stem blight (Phomopsis spp. & Diaporthe spp.). 
Fludioxonil also protects against Helminthosporium, and weakly pathogenic fungi such as 
Aspergillus and Penicillium. 
Sedaxane fungicide is active against seed decay, seedling blight and damping-off caused by 
Rhizoctonia species. 
3.1 Resistance Management 
 
THIAMETHOXAM GROUP 4A INSECTICIDE 
 
For resistance management, CruiserMaxx APX contains thiamethoxam, a Group 4A 
insecticide. Any insect population may contain individuals naturally resistant to CruiserMaxx 
APX and other Group 4A insecticides. The resistant individuals may dominate the insect

CruiserMaxx APX 
Page 7 
population if this group of insecticides are used repeatedly in the same fields. Appropriate 
resistance-management strategies should be followed. 
Thiamethoxam is a systemic insecticide belonging to the neonicotinoid class of chemistry 
which includes nicotinic acetylcholine receptor (nAChR) agonists. 
To delay insecticide resistance, take the following steps: 
x Rotate the use of CruiserMaxx APX or other Group 4A insecticides within a growing 
season, or among growing seasons, with different groups that control the same pests. 
x Use tank mixtures with insecticides from a different group that are equally effective on 
the target pest when such use is permitted. Do not rely on the same mixture 
repeatedly for the same pest population. Consider any known cross-resistance issues 
(for the targeted pests) between the individual components of a mixture. In addition, 
consider the following recommendations provided by the Insecticide Resistance Action 
Committee (IRAC): 
o Individual insecticides selected for use in mixtures should be highly effective 
and be applied at the rates at which they are individually registered for use 
against the target species. 
o Mixtures with components having the same IRAC mode of action classification 
are not recommended for insect resistance management. 
o When using mixtures, consider any k nown cross-resistance issues between the 
individual components for the targeted pest(s). 
o Mixtures become less effective if resistance is already developing to one or 
both active ingredients, but they may still provide pest management benefits. 
o The insect resistance management benefits of an insecticide mixture are 
greatest if the two components have similar periods of residual insecticidal 
activity. Mixtures of insecticides with unequal periods of residual insecticide 
activity may offer an insect resistance management benefit only for the period 
where both insecticides are active. 
x Adopt an integrated pest management program for insecticide/acaricides use that 
includes scouting, uses historical information related to pesticide use, crop rotation, 
record keeping, and which considers cultural, biological and other chemical control 
practices. 
x Monitor after application for unexpected target pest survival. If the level of survival 
suggests the presence of resistance, consult with your local university specialist or 
certified pest control advisor. 
x Contact your local extension specialist or certified crop advisors for any additional 
pesticide resistance-management and/or IPM recommendations for the specific site 
and pest problems in your area. 
x For further information or to report suspected resistance contact Syngenta at 1-866-
796-4368. 
 
Syngenta encourages responsible product stewardship to ensure effective long-term 
protection from the insect pests on this label.

CruiserMaxx APX 
Page 8 
MEFENOXAM GROUP 4 FUNGICIDE 
SEDAXANE GROUP 7 FUNGICIDE 
FLUDIOXONIL GROUP 12 FUNGICIDE 
PICARBUTRAZOX GROUP U17 FUNGICIDE 
 
For resistance management, please note that CruiserMaxx APX contains Group 
4/mefenoxam, Group 7/sedaxane, Group 12/fludioxonil and Group U17/picarbutrazox 
fungicides. Any fungal population may contain individuals naturally resistant to CruiserMaxx 
APX and other Group 4, Group 7, Group 12 and Group U17 fungicides. A gradual or total 
loss of pest control may occur over time if these fungicides are used repeatedly in the same 
fields. Appropriate resistance-management strategies should be followed. 
To delay fungicide resistance, take one or more of the following steps: 
x Rotate the use of CruiserMaxx APX or other Group 4, Group 7, Group 12 or Group U17 
fungicides within a growing season sequence with different groups that control the same 
pathogens. 
x Use tank mixtures with fungicides from a different group that are equally effective on the 
target pest when such use is permitted. Use at least the minimum application rate as 
labeled by the manufacturer. 
x Adopt an integrated disease management program for fungicide use that includes 
scouting, uses historical information related to pesticide use, and crop rotation, and which 
considers host plant resistance, impact of environmental conditions on disease 
development, disease thresholds, as well as cultural, biological and other chemical control 
practices. 
x Where possible, make use of predictive disease models to effectively time fungicide 
applications. Note that using predictive models alone is not sufficient to manage 
resistance. 
x Monitor treated fungal populations for resistance development. 
x Contact your local extension specialist or certified crop advisor for any additional pesticide 
resistance-management and/or IPM recommendations for specific crop and pathogens. 
x For further information or to report suspected resistance contact Syngenta at 1-866-
Syngent(a) (866-796-4368). You can also contact your pesticide distributor or university 
extension specialist to report resistance. 
 
Syngenta encourages responsible product stewardship to ensure effective long-term control 
of the fungal diseases on this label. 
For additional information on Fungicide Resistance Management: 
x Contact Syngenta representatives at 1-866-796-4368. 
x Contact your local extension specialist or certified crop advisor. 
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4.0 APPLICATION DIRECTIONS

CruiserMaxx APX 
Page 9 
4.1 Mixing Directions 
Important: Always re-circulate CruiserMaxx APX thoroughly before using. 
 
The typical density of CruiserMaxx APX is 9.35 pounds per gallon. Consult the manufacturer 
of the application equipment you plan to use for suitability for this application and for 
instructions on operation and calibration of the equipment. Follow the manufacturer 
application instructions for the seed treatment equipment being used. 
 
Apply CruiserMaxx APX as a water-based slurry utilizing standard slurry seed treatment 
equipment which provides uniform seed coverage. Uneven or incomplete seed coverage 
may not give the desired level of disease control. Thoroughly mix the specified amount of 
CruiserMaxx APX into the required amount of water or liquid inoculant for the slurry treater 
and dilution rate to be used. 
 
Certain crops require addition of inoculants when the seed is treated or planted. CruiserMaxx 
APX is compatible with several liquid inoculant products. Consult the maker of the inoculant 
product and a Syngenta representative for directions before applying CruiserMaxx APX with 
inoculants. 
 
The total application volume must be sufficient to provide desired level of coverage. Dilution 
is typically done with water or liquid inoculants. The minimum slurry volume to achieve 
adequate coverage is 4.0 fluid ounces per 100 pounds of seed. More diluent may be 
required to obtain complete coverage. 
 
Continuous agitation or mixing of the slurry mixture is necessary to prevent settling out of the 
solution. 
 
Allow seed to dry before bagging. 
 
Follow planter manufacturer specifications for use of talc or other hopper box additives at 
planting. Seed must be completely dry before adding to planter. 
 
Required Dye Statement: Seed treated with this product must be visually identifiable from untreated 
seed by the use of an approved colorant or dye to prevent accidental use of treated seed as food for 
humans or feed for animals. Refer to 21 CFR, Part 2.25. Any colorant or dye added to treated seed 
must be cleared for use in accordance with 40 CFR, Part 153.155(c).
 
4.1.1 Tank-Mix Precautions 
Mixing CruiserMaxx APX with tank-mix partners: Add 1/2 of the required water to the mix tank 
and turn on the agitation. 
 
Mechanical agitation is preferred. Follow WALES method for mixing order of seed treatment 
products. Allow each tank-mix partner to completely disperse before adding the next product. 
Add the remaining amount of water and agitate. Maintain agitation until the entire slurry 
mixture has been used.

CruiserMaxx APX 
Page 10 
Continuous agitation or mixing of the slurry mixture is necessary to prevent settling out of the 
solution. Clean out any unused product from the treater after treating or maintain constant 
agitation if the leftover slurry will be maintained overnight. 
 
It is the pesticide user’s responsibility to ensure that all products are registered for the 
intended use. Read and follow the applicable restrictions and limitations and directions for 
use on all product labels involved in tank mixing. Users must follow the most restrictive 
directions for use and precautionary statements of each product in the tank mixture. 
 
4.1.2 Tank-Mix Compatibility 
When mixing CruiserMaxx APX with other seed treatment products, test the compatibility 
prior to use by conducting a jar test: mix all intended seed treatments with the appropriate 
amount of water in a clear glass container. Mix well and allow mixture to sit for one hour. 
Remix and observe for incompatibility.

CruiserMaxx APX 
Page 11 
5.0 ROTATIONAL CROP RESTRICTIONS 
x In the event of crop failure or harvest of a crop grown from seed treated with 
CruiserMaxx APX, the field may be replanted according to the following schedule: 
 
Plantback Interval Table 
Immediate Plantback Minimum 30-Day 
Plantback Interval 
Corn (Field, Pop, Sweet) 
Soybean 
 
Alfalfa 
Canola 
Cereal Grains Crop Group 15 
Cotton 
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Dried Shelled Pea and Bean (except 
soybean) Crop Group 6C 
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Head and Stem Brassica Crop Subgroup 
5A 
Leafy Brassica Greens Crop Subgroup 
5B 
/HDI\9HJHWDEOHV&URS*URXS 
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Crop Group 6 
Mint: Peppermint and Spearmint 
Oilseeds: Borage, Crambe, Flax Seed, 
and Mustard Seed 
Onion, Dry Bulb Peanut 
Potato 
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Safflower 
Strawberry 
Sugarbeet 
Sunflower 
Tobacco 
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Potato) Crop Subgroup 1D 
 
 
x For any other crops the minimum plant back interval is 120 days from the date the 
soybean seeds treated with CruiserMaxx APX were planted. A cover crop other than 
the crops listed above that is planted for erosion control or soil improvement may be 
planted sooner than the 120-day interval; however, the crop may not be grazed or 
harvested for food or feed.

CruiserMaxx APX 
Page 12 
6.0 RESTRICTIONS AND PRECAUTIONS 
6.1 Use Restrictions 
x Maximum usage when applying both metalaxyl- and mefenoxam-containing products 
to the same crop within the same season: DO NOT apply more than the maximum 
seasonal total for the active ingredient as stated on the label of the product containing 
the lowest seasonal total on that crop. 
x DO NOT use at a rate that will result in more than 0.266 lb thiamethoxam per acre 
(120 grams ai/A) per calendar year, regardless of type of application (seed treatment 
and/or foliar). 
x DO NOT use at a rate that will result in more than 0.083 lb thiamethoxam per acre 
(37.8 grams ai/A) per calendar year as a seed treatment application. This seed has 
been treated with 0.0756 mg ai thiamethoxam per seed. 
x DO NOT apply more than 0.004 lb (2.0 g) of fludioxonil per acre per calendar year as a 
seed treatment. This seed has been treated with 0.0039 mg ai fludioxonil per seed. 
x DO NOT apply more than 0.013 lb (5.7 g) of mefenoxam per acre per calendar year as 
a seed treatment. This seed has been treated with 0.0114 mg ai mefenoxam per seed. 
x DO NOT apply more than 0.004 lb (2.0 g) of sedaxane per acre per calendar year as a 
seed treatment. This seed has been treated with 0.0039 mg ai sedaxane per seed. 
x DO NOT apply more than 0.004 lb (2.0 g) of picarbutrazox per acre per calendar year 
as a seed treatment. This seed has been treated with 0.0039 mg ai picarbutrazox per 
seed. 
x DO NOT plant more than 250,000 soybean seed per acre. 
x DO NOT apply a neonicotinoid insecticide within 45 days of planting seed treated with 
CruiserMaxx APX. 
x This treated seed may be planted on the same acres up to 2 times per year. 
x DO NOT use for feed, food, or oil purposes. 
x Required Dye Statement: Seed treated with this product must be visually identifiable 
from untreated seed by the use of an approved colorant or dye to prevent accidental 
use of treated seed as food for humans or feed for animals. Refer to 21 CFR, Part 
2.25. Any colorant or dye added to treated seed must be cleared for use in accordance 
with 40 CFR, Part 153.155(c). 
x DO NOT allow children, pets, or livestock to have access to treated seed. 
x Store away from feed and foodstuffs. 
x Treated seed must be planted into the soil at a depth greater than 1 inch.

CruiserMaxx APX 
Page 13 
7.0 SEED CONTAINER LABEL REQUIREMENTS 
7.1 Use of On-Farm Treated Seed (when treated seed are not 
for sale or distribution) 
Treated seed sold or distributed for a use not permitted by the following labeling does not 
qualify as an exempted treated article under 40 CFR 152.25(a) and is therefore sale or 
distribution of an unregistered pesticide, pursuant to FIFRA section 12. 
x Store treated seed away from food and feedstuffs. 
x DO NOT allow children, pets, or livestock to have access to treated seed. 
x Treated seed are for planting purposes only. DO NOT use for food, feed, or oil 
purposes. DO NOT use treated seed for fuel or ethanol production purposes. 
x Wear long-sleeved shirt, long pants, sh oes, socks, and chemical-resistant gloves 
when handling treated seed. 
x DO NOT plant treated seed by broadcasting to the soil surface. Ensure that all planted 
seed are thoroughly incorporated by the planter during planting. Additional 
incorporation may be required to thoroughly cover exposed seed. 
x Treated seed exposed on the soil surface may be hazardous to wildlife. Cover or 
collect treated seed spilled during loading and planting (such as in row ends). 
x Treated seed must be planted into the soil at a depth greater than 1 inch. 
x Manage excess treated seed (e.g., spilled, u nused, or expired treated seed) by one or 
more of the following methods: 
o Collect excess treated seed for reuse for planting. 
o Bury excess treated seed (only allowed if totaling 1 pound or less) at least 30 
feet away from bodies of water at a depth of 6 inches or double the planting 
depth, whichever is greater. 
o Dispose of excess treated seed by plac ing them in a landfill in accordance with 
applicable laws in your state. 
o Return excess treated seed to the supplier if permitted by the state. 
x Advisory Dust-Reducing Technique: The use of seed flow lubricants or polymer 
coatings may help decrease the amount of dust released during planting. Follow the 
recommendations of the planter manufacturer regarding the use of seed flow 
lubricants. 
x This treated seed may be planted on the same acres up to 2 times per year.

CruiserMaxx APX 
Page 14 
7.2 Seed Treatment in Commercial Facilities or Seed 
Treatment On-Farm (when treated seed are to be sold or 
distributed) – Seed Bag Labeling Requirements 
The Federal Seed Act requires that bags containing treated seed shall be labeled with the 
following statements: 
x This seed has been treated with thiamethoxam insecticide and fludioxonil, 
mefenoxam, picarbutrazox and sedaxane fungicides. 
x DO NOT use for food, feed, or oil purposes. 
 
The U.S. Environmental Protection Agency requires that bags containing treated seed shall 
be labeled with the following statements. Any seed treated with CruiserMaxx APX that is sold 
or distributed without these statements or that is sold or distributed for a use not permitted by 
the following labeling does not qualify as an exempted treated article under 40 CFR 
152.25(a) and is therefore sale or distribution of an unregistered pesticide, pursuant to FIFRA 
section 12(a)(1)(A). 
This seed has been treated with CruiserMaxx APX (EPA Reg No. 100-1690) containing 
fludioxonil, mefenoxam, picarbutrazox, sedaxane, and thiamethoxam. Any seed treated with 
CruiserMaxx APX that is sold or distributed for a use not permitted by the following labeling 
does not qualify as an exempted treated article under 40 CFR 152.25(a) and is therefore sale 
or distribution of an unregistered pesticide, pursuant to FIFRA section 12(a)(1)(A). 
 
x The contents of this bag are for planting purposes only. DO NOT use for food, feed, or 
oil purposes. DO NOT use for fuel or ethanol production purposes. 
x Advisory Dust-Reducing Technique: The use of seed flow lubricants or polymer 
coatings may help decrease the amount of dust released during planting. Follow the 
recommendations of the planter manufacturer regarding the use of seed flow 
lubricants. 
x Groundwater Advisory: Mefenoxam is known to leach through soil into groundwater 
under certain conditions as a result of agricultural use. Fludioxonil and Thiamethoxam 
have properties and characteristics associated with chemicals detected in 
groundwater. Mefenoxam, Fludioxonil, and Thiamethoxam may leach into 
groundwater if used in areas where soils are permeable, particularly where the water 
table is shallow. 
 
x Pollinator Precautions: Thiamethoxam is highly toxic to bees and other pollinating 
insects, and effects are possible as a result of exposure to translocated residues in 
blooming crops. 
x DO NOT allow children, pets, or livestock to have access to treated seed. 
x Store treated seed away from food and feedstuffs. 
x Wear long-sleeved shirt, long pants and chemical resistant gloves when handling 
treated seed. 
x DO NOT plant treated seed by broadcasting to the soil surface. Ensure that all planted 
seed are thoroughly incorporated by the planter during planting. Additional 
incorporation may be required to thoroughly cover exposed seed. 
x Treated seed exposed on soil surface may be hazardous to wildlife. Cover or collect 
treated seed spilled during loading and planting (such as in row ends).

CruiserMaxx APX 
Page 15 
x Manage excess treated seed (e.g., spilled, u nused, or expired treated seed) by one or 
more of the following methods: 
o Collect excess treated seed for reuse for planting. 
o Bury excess treated seed (only allowed if totaling 1 pound or less) at least 30 
feet away from bodies of water at a depth of 6 inches or double the planting 
depth, whichever is greater. 
o Dispose of excess treated seed by plac ing them in a landfill in accordance with 
applicable laws in your state. 
o Return excess treated seed to the supplier if permitted by the state. 
x Treated seed must be planted into the soil at a depth greater than 1 inch. 
x DO NOT contaminate water bodies when disposing of planting equipment wash 
waters. 
x Dispose of seed packaging in accordance with local requirements. 
x In the event of crop failure or harvest of a crop grown from seed treated with 
CruiserMaxx APX, the field may be replanted according to the following schedule: 
 
Plantback Interval Table 
Immediate Plantback Minimum 30-Day 
Plantback Interval 
Corn (Field, Pop, Sweet) 
Soybean 
 
Alfalfa 
Canola 
Cereal Grains Crop Group 15 
Cotton 
&XFXUELW9HJHWDEOHV&URS*URXS 
Dried Shelled Pea and Bean (except 
soybean) Crop Group 6C 
)UXLWLQJ9HJHWDEOHV&URS*URXS 
Head and Stem Brassica Crop Subgroup 
5A 
Leafy Brassica Greens Crop Subgroup 
5B 
/HDI\9HJHWDEOHV&URS*URXS 
/HJXPH9HJHWDEOHV6XFFXOHQWRU'ULHG
Crop Group 6 
Mint: Peppermint and Spearmint 
Oilseeds: Borage, Crambe, Flax Seed, 
and Mustard Seed 
Onion, Dry Bulb Peanut 
Potato 
5RRW9HJHWDEOHV&URS6XEJURXS$ 
Safflower 
Strawberry 
Sugarbeet

CruiserMaxx APX 
Page 16 
Sunflower 
Tobacco 
7XEHURXVDQG&RUP9HJHWDEOHV([FHSW
Potato) Crop Subgroup 1D 
 
x For any other crops the minimum plant back interval is 120 days from the date the 
seeds treated with CruiserMaxx APX were planted. A cover crop other than the crops 
listed above that is planted for erosion control or soil improvement may be planted 
sooner than the 120-day interval; however, the crop may not be grazed or harvested 
for food or feed. 
x DO NOT use at a rate that will result in more than 0.266 lb thiamethoxam per acre 
(120 grams ai/A) per calendar year, regardless of type of application (seed treatment 
and/or foliar). DO NOT use at a rate that will result in more than 0.083 lb 
thiamethoxam per acre (37.8 grams ai/A) per calendar year as a seed treatment 
application. DO NOT apply more than 0.004 lb (2.0 g) of fludioxonil per acre per 
calendar year as a seed treatment. DO NOT apply more than 0.013 lb (5.7 g) of 
mefenoxam per acre per calendar year as a seed treatment. DO NOT apply more than 
0.004 lb (2.0 g) of sedaxane per acre per calendar year as a seed treatment. DO NOT 
apply more than 0.004 lb (2.0 g) of picarbutrazox per acre per calendar year as a seed 
treatment. 
x This seed has been treated with 0.0756 mg ai thiamethoxam, 0.0039 mg ai fludioxonil, 
0.0114 mg ai mefenoxam, 0.0039 mg ai sedaxane, and 0.0039 mg ai picarbutrazox 
per seed. 
x DO NOT plant more than 250,000 soybean seed per acre. 
x DO NOT apply a neonicotinoid insecticide within 45 days of planting seed treated with 
CruiserMaxx APX. 
x This treated seed may be planted on the same acres up to 2 times per year. 
x [All seed bag tags must be legible and set in at least 8-point font size.]

CruiserMaxx APX 
Page 17 
8.0 CROP USE DIRECTIONS 
When applied according to the CruiserMaxx APX Rate Table, CruiserMaxx APX provides 
early season protection against injury by aphids, bean leaf beetle, grape colaspis, leaf 
miners, leaf hoppers, Mexican bean beetle, seed corn maggot, three-cornered alfalfa hopper, 
thrips, white grubs, and wireworm. 
 
CruiserMaxx APX also provides protection against damping-off and seed borne rots due to 
Pythium, Phytophthora, Fusarium, Rhizoctonia species and early season Phytophthora root 
rot as well as Anthracnose on soybean caused by seed-borne Colletotrichum spp. 
CruiserMaxx APX also provides protection from seed-borne Diaporthe-Phomopsis disease 
complex sometimes referred to as pod and stem blight (Phomopsis spp. & Diaporthe spp.), 
Helminthosporium, and weakly pathogenic fungi such as Aspergillus and Penicillium. 
Additional Apron XL
® or similar fungicide may be necessary for high levels of Phytophthora or 
Pythium. Read and follow all label direction for Apron XL use. 
 
It is the pesticide user's responsibility to ensure that all products in a tank mix are registered 
for the intended use. Users must follow the most restrictive directions and precautionary 
language of the products of the mixture (for example, first aid from one product, REI from 
another).

CruiserMaxx APX 
Page 18 
8.1 Soybean 
CruiserMaxx APX Rate Table 
Crop Rate of CruiserMaxx APX 
Soybean fl oz per 
100 lb seed1 
or 
fl oz per 140,000 
seeds1 
grams ai per 
100 kg seed 
mg ai 
per seed 
 
4.18 fl oz per 100 
lb seed 
or 
1.95 fl oz per 
140,000 seeds 
 
Thiamethoxam 50 gm 
 
Picarbutrazox 2.6 gm 
 
Mefenoxam 7.5 gm 
 
Fludioxonil 2.6 gm 
 
Sedaxane 2.6 gm 
 
Total = 65.3 gm 
 
Total of all active ingredients = 
0.0983 mg 
 
1The mg ai per seed, fl oz CruiserMaxx APX per 100 lb seed, and fl oz CruiserMaxx APX per 140,000 seeds 
rates are based on 3,000 soybean seeds per pound. 
 
STORED GRAIN PROTECTION 
When treated according to the directions for post-planting protection against listed pests, 
CruiserMaxx APX will also provide protection during post treatment storage of the seed listed 
on this label against damage from the following stored grain insects: Indian Meal Moth 
(Plodia interpunctella), Rice Weevil (Sitophilus oryza), Red Flour Beetle (Tribolium 
castaneum), and Lesser Grain Borer (Rhizopertha dominica). 
If the seed to be treated has existing infestations of stored grain insects, fumigate the seed 
with a registered product approved for such use prior to treating with CruiserMaxx APX and 
bagging. 
9.0 STORAGE AND DISPOSAL 
STORAGE AND DISPOSAL 
DO NOT contaminate water, food, or feed by storage or disposal. 
Pesticide Storage 
Store in the original container and only in a cool, dry, secure place. Store between a range of 
32°F to 100°F. 
 
For minor spills, leaks, etc., follow all precautions indicated on this label and clean up 
immediately. Take special care to avoid contamination of equipment and facilities during 
cleanup procedures and disposal of wastes.

CruiserMaxx APX 
Page 19 
 
Pesticide Disposal 
Wastes resulting from the use of this product must be disposed of on site or at an approved 
waste disposal facility. If these wastes cannot be disposed of by use according to label 
instructions, contact your State Pesticide or Environmental Control Agency, or the Hazardous 
Waste Representative at the nearest EPA Regional Office for guidance. 
 
Container Handling [(less than or equal to 5 gallons)] 
Non-refillable container. DO NOT reuse or refill this container. Triple rinse container (or 
equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents 
into application equipment or a mix tank and drain for 10 seconds after the flow begins to 
drip. Fill the container ¼ full with water and recap. Shake for 10 seconds. Pour rinsate into 
application equipment or a mix tank or store rinsate for later use or disposal. Drain for 10 
seconds after the flow begins to drip. Repeat this procedure two more times. Then offer for 
recycling if available or puncture and dispose of in a sanitary landfill, or by incineration, or by 
other procedures approved by state and local authorities. 
 
Container Handling [(greater than 5 gallons)] 
Non-refillable container. DO NOT reuse or refill this container. Triple rinse container (or 
equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents 
into application equipment or a mix tank. Fill the container ¼ full with water. Replace and 
tighten closures. Tip container on its side and roll it back and forth, ensuring at least one 
complete revolution, for 30 seconds. Stand the container on its end and tip it back and forth 
several times. Turn the container over onto its other end and tip it back and forth several 
times. Empty the rinsate into application equipment or a mix tank or store rinsate for later 
use or disposal. Repeat this procedure two more times. Then offer for recycling if available 
or puncture and dispose of in a sanitary landfill, or by incineration, or by other procedures 
approved by state and local authorities. 
 
Container Handling [(greater than 5 gallons)] 
Refillable container. Refill this container with pesticide only. DO NOT reuse this container 
for any other purpose. Cleaning the container before final disposal is the responsibility of the 
person disposing of the container. Cleaning before refilling is the responsibility of the person 
refilling. To clean container before final disposal, empty the remaining contents from this 
container into application equipment or mix tank. Fill the container about 10 percent full with 
water. Agitate vigorously or recirculate water with the pump for 2 minutes. Pour or pump 
rinsate into application equipment or rinsate collection system. Repeat this rinsing procedure 
two more times. Then offer for recycling if available or puncture and dispose of in a sanitary 
landfill, or by incineration, or by other procedures approved by state and local authorities. 
CONTAINER IS NOT SAFE FOR FOOD, FEED, OR DRINKING WATER.

CruiserMaxx APX 
Page 20 
10.0 CONDITIONS OF SALE AND LIMITATION OF WARRANTY 
AND LIABILITY 
NOTICE: Read the entire Directions for Use and Conditions of Sale and Limitation of 
Warranty and Liability before buying or using this product. If the terms are not acceptable, 
return the product at once, unopened, and the purchase price will be refunded. 
The Directions for Use of this product must be followed carefully. It is impossible to eliminate 
all risks inherently associated with the use of this product. Crop injury, ineffectiveness or 
other unintended consequences may result because of such factors as manner of use or 
application, weather or crop conditions, presence of other materials or other influencing 
factors in the use of the product, which are beyond the control of SYNGENTA CROP 
PROTECTION, LLC or Seller. To the extent permitted by applicable law, Buyer and User 
agree to hold SYNGENTA and Seller harmless for any claims relating to such factors. 
SYNGENTA warrants that this product conforms to the chemical description on the label and 
is reasonably fit for the purposes stated in the Directions for Use, subject to the inherent risks 
referred to above, when used in accordance with directions under normal use conditions. To 
the extent permitted by applicable law: (1) this warranty does not extend to the use of the 
product contrary to label instructions, or under conditions not reasonably foreseeable to or 
beyond the control of Seller or SYNGENTA, and (2) Buyer and User assume the risk of any 
such use. TO THE EXTENT PERMITTED BY APPLICABLE LAW, SYNGENTA MAKES NO 
WARRANTIES OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE 
NOR ANY OTHER EXPRESS OR IMPLIED WARRANTY EXCEPT AS WARRANTED BY 
THIS LABEL. 
To the extent permitted by applicable law, in no event shall SYNGENTA be liable for any 
incidental, consequential or special damages resulting from the use or handling of this 
product. TO THE EXTENT PERMITTED BY APPLICABLE LAW, THE EXCLUSIVE 
REMEDY OF THE USER OR BUYER, AND THE EXCLUSIVE LIABILITY OF SYNGENTA 
AND SELLER FOR ANY AND ALL CLAIMS, LOSSES, INJURIES OR DAMAGES 
(INCLUDING CLAIMS BASED ON BREACH OF WARRANTY, CONTRACT, 
NEGLIGENCE, TORT, STRICT LIABILITY OR OTHERWISE) RESULTING FROM THE 
USE OR HANDLING OF THIS PRODUCT, SHALL BE THE RETURN OF THE PURCHASE 
PRICE OF THE PRODUCT OR, AT THE ELECTION OF SYNGENTA OR SELLER, THE 
REPLACEMENT OF THE PRODUCT. 
SYNGENTA and Seller offer this product, and Buyer and User accept it, subject to the 
foregoing Conditions of Sale and Limitation of Warranty and Liability, which may not be 
modified except by written agreement signed by a duly authorized representative of 
SYNGENTA. 
 
Apron XL
®, CruiserMaxx®, the ALLIANCE FRAME, the SYNGENTA Logo, and the 
PURPOSE ICON are Trademarks of a Syngenta Group Company 
9LWRQ™ is a trademark of The Chemours Company FC, LLC

CruiserMaxx APX 
Page 21 
©20XX Syngenta 
 
 
For non-emergency (e.g. current product information), call 
Syngenta Crop Protection at 1-866-796-4368. 
 
 
Manufactured for: 
Syngenta Crop Protection, LLC 
P.O. Box 18300 
Greensboro, North Carolina 27419-8300 
 
 
 
CruiserMaxx APX 1690 MAS 0921 AMEND-B FEB2026-CL – jeb – 05/22/2026 
000100-01690.20260216B.CRUISERMAXX_APX.AMEND.0226-CL