crop-chem-docs/corpus/epa_ppls/100-1731.md

# A23545 ST

- EPA Reg No: **100-1731**
- Registrant: SYNGENTA CROP PROTECTION, LLC
- Signal word: Caution
- Active ingredients: Picarbutrazox (1.81%); Fludioxonil (1.81%); Metalaxyl-M (7.24%); Sedaxane (1.81%)
- Label accepted: 2026-08-12
- Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/000100-01731-20260812.pdf

---
August 12, 2026
Patsy Laird
Regulatory Manager, Seedcare
Syngenta Crop Protection, LLC
P.O. Box 18300
Greensboro, NC 27419
Subject: Label Amendment - Registration Review Mitigation for Sedaxane
 Product Name: A23545 ST
EPA Registration Number: 100-1731
 Application Date: February 13, 2026
Case Number: 684655
Dear Mrs. Patsy Laird:
The Agency, in accordance with the Federal Insecticide, Fungicide, and Rodenticide Act 
(FIFRA), as amended, has completed reviewing all the information submitted with your 
application to support the Registration Review of the above referenced product in 
connection with the Sedaxane Interim Decision, and has concluded that your submission 
is acceptable. The label referred to above, submitted in connection with registration under 
FIFRA, as amended, is acceptable.
Should you wish to add/retain a reference to the company’s website on your label, then 
please be aware that the website becomes labeling under the Federal Insecticide, 
Fungicide, and Rodenticide Act and is subject to review by the Agency. If the website is
false or misleading, the product would be misbranded and unlawful to sell or distribute 
under FIFRA section 12(a)(1)(E). 40 CFR 156.10(a)(5) list examples of statements EPA may 
consider false or misleading. In addition, regardless of whether a website is referenced on 
your product’s label, claims made on the website may not substantially differ from those 
claims approved through the registration process. Therefore, should the Agency find or if it 
is brought to our attention that a website contains false or misleading statements or 
claims substantially differing from the EPA approved registration, the website will be 
referred to the EPA’s Office of Enforcement and Compliance Assurance.

Page 2 of 2
EPA Reg. No. 100-1731
Decision No. 684655
A stamped copy of your labeling is enclosed for your records. This labeling 
supersedes all previously accepted labeling and must be used at your next label 
printing. You must submit one copy of the final printed labeling before you release 
the product for shipment with the new labeling. In accordance with 40 CFR 
152.130(c), you may distribute or sell this product under the previously approved 
labeling for 12 months from the date of this letter. After 12 months, you may only 
distribute or sell this product if it bears this new revised labeling or subsequently 
approved labeling. “To distribute or sell” is defined under FIFRA section 2(gg) and 
its implementing regulation at 40 CFR 152.3.
If you have any questions about this letter, please contact Samantha Carter by phone at 
202-566-1179, or via email at carter.samantha@epa.gov. 
Sincerely,
Jaclyn Pyne, Team Leader
Risk Management and Implementation Branch 3
Pesticide Re-Evaluation Division
Office of Pesticide Programs
ENCLOSURE: Stamped label

[Master Label]
MEFENOXAM GROUP 4 FUNGICIDE
SEDAXANE GROUP 7 FUNGICIDE
FLUDIOXONIL GROUP 12 FUNGICIDE
PICARBUTRAZOX GROUP U17 FUNGICIDE
A23545 ST
[Alternate Brand Name: Vayantis® Quattro]
Fungicide
A seed treatment product for protection against damage from listed seed-borne and seedling 
diseases on soybean
Active Ingredient:
Mefenoxam
1 ..............................................................................................................7.24%
Fludioxonil2 ................................................................................................................1.81%
Picarbutrazox3 ...........................................................................................................1.81%
Sedaxane4 .................................................................................................................1.81%
Other Ingredients: 87.33%
Total: 100.00%
1CAS No. 70630-17-0 and 69516-34-3
2CAS No. 131341-86-1
3CAS No. 500207-04-5
4CAS No. 874967-67-6
A23545 ST is a flowable concentrate for seed treatment containing 0.64 lb mefenoxam, 0.16 
lb fludioxonil, 0.16 lb picarbutrazox, and 0.16 lb sedaxane per gallon.
KEEP OUT OF REACH OF CHILDREN.
CAUTION
See additional precautionary statements and directions for use in booklet.
EPA Reg. No. 100-1731
EPA Est. No. 
__________
Net Contents
[Batch Code: _____ ] (For nonrefillables only.)
Aug 12, 2026
100-1731

A23545 ST 
2 
 
TABLE OF CONTENTS 
 
1.0 FIRST AID 
2.0 PRECAUTIONARY STATEMENTS 
2.1 Hazards to Humans and Domestic Animals 
2.2 Personal Protective Equipment (PPE) 
2.3 User Safety Requirements 
2.4 Engineering Controls 
2.5 User Safety Recommendations 
2.6 Environmental Hazards 
2.6.1 Groundwater Advisory 
2.7 Physical or Chemical Hazards 
DIRECTIONS FOR USE 
3.0 PRODUCT INFORMATION 
3.1 Resistance Management 
4.0 APPLICATION DIRECTIONS 
4.1 Tank Mixtures 
5.0 RESTRICTIONS 
6.0 SEED CONTAINER LABEL REQUIREMENTS 
6.1 Use of On-Farm Treated Seed (when treated seed are not for sale or distribution) 
6.2 Seed Treatment in Commercial Facilities or Seed Treatment on Farm (when treated seed 
are to be sold or distributed) – Seed Bag Labeling Requirements 
7.0 SEED TREATMENT DIRECTIONS 
7.1 Soybean 
8.0 STORAGE AND DISPOSAL 
9.0 CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY

A23545 ST 
3 
 
1.0 FIRST AID 
FIRST AID 
If swallowed x Call a poison control center or doctor immediately for treatment 
advice. 
x Have a person sip a glass of water if able to swallow. 
x Do not induce vomiting unless told to do so by a poison control 
center or doctor. 
x Do not give anything by mouth to an unconscious person. 
If on skin or 
clothing 
x Take off contaminated clothing. 
x Rinse skin immediately with plenty of water for 15-20 minutes. 
x Call a poison control center or doctor for treatment advice. 
Have the product container or label with you when calling a poison control center or 
doctor, or going for treatment. 
HOTLINE NUMBER 
For 24-Hour Medical Emergency Assistance (Human or Animal) 
Or Chemical Emergency Assistance (Spill, Leak, Fire or Accident) 
Call 
1-800-888-8372 
 
2.0 PRECAUTIONARY STATEMENTS 
2.1 Hazards to Humans and Domestic Animals 
 
CAUTION 
 
Harmful if swallowed or absorbed through skin. Avoid contact with skin, eyes or clothing. Wash 
thoroughly with soap and water after handling and before eating, drinking, chewing gum, using 
tobacco or using the toilet. Remove and wash contaminated clothing before reuse. 
2.2 Personal Protective Equipment (PPE) 
Applicators and other handlers must wear: 
x Long-sleeved shirt and long pants 
x Chemical-resistant gloves made of EDUULHUODPLQDWHEXW\OUXEEHU•PLOVQHRSUHQH
UXEEHU•PLOVQLWULOHUXEEHU•PLOVSRO\YLQ\OFKORULGH39&•PLOV, or Viton™ 
•PLOV 
x Shoes plus socks 
2.3 User Safety Requirements 
Follow manufacturer’s instructions for cleaning/maintaining PPE. If no such instructions for 
washables exist, use detergent and hot water. Keep and wash PPE separately from other 
laundry.

A23545 ST 
4 
 
2.4 Engineering Controls 
When handlers use closed systems, enclosed cabs, or aircraft in a manner that meets the 
requirements listed in the Worker Protection Standard (WPS) for agricultural pesticides (40 
CFR 170.607 (d) and (e)), the handler PPE requirements may be reduced or modified as 
specified in the WPS. 
2.5 User Safety Recommendations 
Users should: 
x Remove clothing/PPE immediately if pesticide gets inside. Then wash thoroughly 
and put on clean clothing. Remove PPE immediately after handling this product. 
x Wash the outside of gloves before removing. As soon as possible, wash thoroughly 
and change into clean clothing. 
 
2.6 Environmental Hazards 
This product is toxic to fish and aquatic invertebrates. For terrestrial uses, DO NOT apply 
directly to water, or to areas where surface water is present, or to intertidal areas below the 
mean high-water mark. DO NOT contaminate water when disposing of equipment 
washwater or rinsate. 
 
2.6.1 Groundwater Advisory 
Mefenoxam is known to leach through soil into groundwater under certain conditions as a 
result of label use. Fludioxonil has properties and characteristics associated with chemicals 
detected in groundwater. These chemicals may leach into groundwater if used in areas 
where soils are permeable, particularly where the water table is shallow. 
 
2.7 Physical or Chemical Hazards 
DO NOT mix or allow contact with oxidizing agents. Hazardous chemical reaction may occur.

A23545 ST 
5 
 
DIRECTIONS FOR USE 
It is a violation of federal law to use this product in a manner inconsistent with its labeling. 
Use is permitted on agricultural establishments and in commercial seed treatment facilities 
only. DO NOT use for at-plant applications (e.g., hopper box, planter box). This product is to 
be applied as a water-based slurry through standard slurry- or mist-type commercial seed 
treatment equipment. 
DO NOT apply this product in a way that will contact workers or other persons, either directly 
or through drift. Only protected handlers may be in the area during application. For any 
requirements specific to your State or Tribe, consult the agency responsible for pesticide 
regulation. Notify state and/or federal authorities and Syngenta immediately if you observe 
any adverse environmental effects due to use of this product. 
FAILURE TO FOLLOW DIRECTIONS, RESTRICTIONS, AND PRECAUTIONS ON THIS 
LABEL MAY RESULT IN CROP INJURY; POOR DISEASE CONTROL; AND/OR ILLEGAL 
RESIDUES. 
Treatment of highly mechanically scarred or damaged seed or seed known to be of low vigor 
and poor quality may result in reduced germination and/or reduction of seed and seedling 
vigor. Treat a quantity of seed using equipment similar to that planned for treating the total 
seed lot. Then conduct germination tests with a portion of this treated seed before 
committing the total seed lot to a selected seed treatment. 
Due to seed quality, crop or variety sensitivity, and seed storage conditions beyond the 
control of Syngenta, no claims are made to guarantee the germination of seed or propagating 
material for any crop seed treated with A23545 ST. 
Maximum usage when applying metalaxyl- and mefenoxam-containing products to the 
same crop within the same season: DO NOT apply more than the maximum yearly total 
application rate for the active ingredient as stated on the label of the product containing the 
lowest yearly total on that crop.

A23545 ST 
6 
 
 
AGRICULTURAL USE REQUIREMENTS 
Use this product only in accordance with its labeling and with the Worker Protection 
Standard, 40 CFR part 170. This Standard contains requirements for the protection of 
agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of 
agricultural pesticides. It contains requirements for training, decontamination, notification, 
and emergency assistance. It also contains specific instructions and exceptions pertaining to 
the statements on this label about personal protective equipment (PPE) and restricted-entry 
interval. The requirements in this box only apply to uses of this product that are covered by 
the Worker Protection Standard (WPS). 
DO NOT enter or allow worker entry into treated areas during the restricted-entry 
interval (REI) of 48 hours. Exception: If the seed is treated with the product and the 
treated seed is planted, the Worker Protection Standard, under certain circumstances, allows 
workers to enter the treated area if there will be no contact with anything that has been 
treated. 
PPE required for early entry to treated areas that is permitted under the Worker Protection 
Standard and that involves contact with anything that has been treated, such as plants, soil, 
or water is: 
x Coveralls 
x Chemical-resistant gloves made of EDUULHUODPLQDWHEXW\OUXEEHU•PLOVQLWULOHUXEEHU
•PLOVQHRSUHQHUXEEHU•PLOV, SRO\YLQ\OFKORULGH39&•PLOV or 9LWRQ•PLOV 
x Shoes plus socks 
 
3.0 PRODUCT INFORMATION 
A23545 ST is a broad-spectrum seed treatment fungicide that consists of four fungicide 
active ingredients: fludioxonil, mefenoxam, picarbutrazox, and sedaxane. Each active 
ingredient has a different mode of action against fungal pathogens. This fungicide seed 
treatment is designed for protection against many important fungal plant diseases. A23545 
ST may be applied in tank mixes or sequentially with other registered seed treatment 
pesticide products such as Cruiser
® 5FS (EPA Reg. No. 100-941, containing thiamethoxam) 
or Fortenza® (EPA Reg. Nos. 100-1418 and 100-1420, containing cyantraniliprole) 
insecticides or Saltro® (EPA Reg. No. 100-1648, containing pydiflumetofen) 
fungicide/nematicide. 
 
Fludioxonil protects against seed-borne and soil-borne Fusarium and Rhizoctonia spp. that 
cause seed decay, damping-off, and seedling blight. This active ingredient also provides 
protection from seed-borne Diaporthe-Phomopsis disease complex sometimes referred to as 
pod and stem blight (Phomopsis and Diaporthe spp.). Fludioxonil suppresses seed-borne 
Sclerotinia and Phomopsis spp. 
 
Mefenoxam is active against Pythium and Phytophthora spp.

A23545 ST 
7 
 
Picarbutrazox provides early-season protection against Pythium and Phytophthora spp. that 
cause seed rot and damping-off. 
 
Sedaxane is active against seed decay, seedling blight, and damping-off caused by 
Rhizoctonia spp. 
 
3.1 Resistance Management 
 
For resistance management, please note that A23545 ST contains fludioxonil, a Group 12 
fungicide; mefenoxam, a Group 4 fungicide; picarbutrazox, a Group U17 fungicide; and 
sedaxane, a Group 7 fungicide. Any fungal population may contain individuals naturally 
resistant to A23545 ST and other Group 4, Group 7, Group 12, or Group U17 fungicides. A 
gradual or total loss of pest control may occur over time if these fungicides are used 
repeatedly in the same fields. Appropriate resistance-management strategies should be 
followed. 
 
Fludioxonil belongs to the phenylpyrrole class of chemistry, which interferes with osmotic 
signal transduction. Mefenoxam belongs to the phenylamide class of chemistry, which 
interferes with fungal RNA synthesis. Picarbutrazox belongs to the tetra-zolyloximes class of 
fungicides and is not known to be cross-resistant with fungicides that have different modes of 
action. Sedaxane is a succinate dehydrogenase inhibitor (SDHI) and belongs to the 
carboxamide class of chemistry, which disrupts cellular respiration and energy generation. 
 
To delay fungicide resistance, take one or more of the following steps: 
x Rotate the use of A23545 ST or other Group 4, Group 7, Group 12, or Group U17 
fungicides within a growing season sequence with different groups that control the same 
pathogens. 
x Use tank mixtures with fungicide from a different group that are equally effective on the 
target pest when such use is permitted. Use at least the minimum application rate as 
labeled by the manufacturer. 
x Adopt an integrated disease management program for fungicide use that includes 
scouting, uses historical information related to pesticide use and crop rotation, and 
considers host plant resistance, impact of environmental conditions on disease 
development, disease thresholds, as well as cultural, biological and other chemical control 
practices. 
x Where possible, make use of predictive disease models to effectively time fungicide 
applications. Note that using predictive models alone is not sufficient to manage 
resistance. 
x Monitor treated fungal populations for resistance development. 
x Contact your local extension specialist or certified crop advisor for any additional pesticide 
resistance-management and/or Integrated Pest Management (IPM) recommendations for 
specific crop and pathogens.

A23545 ST 
8 
 
x For further information or to report suspected resistance contact Syngenta at 1-866-
Syngent(a) (866-796-4368). You can also contact your pesticide distributor or university 
extension specialist to report resistance. 
 
Syngenta encourages responsible product stewardship to ensure effective long-term control 
of the fungal diseases on this label. 
 
4.0 APPLICATION DIRECTIONS 
Important: Always recirculate A23545 ST thoroughly before using. 
 
Follow the manufacturer’s application instructions for the seed treatment equipment being 
used. 
The typical density of A23545 ST is 8.85 pounds per gallon. Consult the manufacturer of the 
application equipment you plan to use for suitability for this application and for instructions on 
operation and calibration of the equipment. Follow the manufacturer’s application instructions 
for the seed treatment equipment being used. 
Apply A23545 ST as a water-based slurry utilizing standard slurry seed treatment equipment 
that provides uniform seed coverage. Seed treaters with atomizers or spinning discs are 
highly recommended for better product coverage on the seed. Uneven or incomplete seed 
coverage may not give the desired level of disease control. Thoroughly mix the specified 
amount of A23545 ST into the required amount of water or liquid inoculant for the slurry 
treater and dilution rate to be used. 
Certain crops require addition of inoculants when the seed is treated or planted. A23545 ST 
is compatible with several liquid inoculant products. Consult the maker of the inoculant 
product and a Syngenta Crop Protection representative for directions before applying A23545 
ST with inoculants. 
Continuous agitation or mixing of the slurry mixture is necessary to prevent settling out of the 
solution. Clean out any unused product from the treater after treating or maintain constant 
agitation if the leftover slurry will be maintained overnight. 
Required Dye Statement: Seed treated with this product must be visually identifiable from 
untreated seed by the use of an approved colorant or dye to prevent accidental use of treated 
seed as food for humans or feed for animals. Refer to 21 CFR, Part 2.25. Any colorant or dye 
added to treated seed must be cleared for use in accordance with 40 CFR, Part 153.155(c). 
Allow seed to dry before bagging. 
Follow planter manufacturer’s specifications for use of talc or other hopper box additives at 
planting. Seed must be completely dry before adding to planter. 
 
4.1 Tank Mixtures

A23545 ST 
9 
 
A23545 ST mixes easily with water and other water-based seed treatments manufactured by 
Syngenta. When mixing with products from other manufacturers, test the compatibility prior 
to use by conducting a jar test: mix all intended seed treatments with the appropriate amount 
of water in a clear glass container. Mix well and allow mixture to sit for one hour. Remix and 
observe for incompatibility. 
It is the pesticide user’s responsibility to ensure that all products are registered for the 
intended use. Read and follow the applicable restrictions and limitations and directions for 
use on all product labels involved in tank mixing. Users must follow the most restrictive 
directions for use and precautionary statements of each product in the tank mixture.

A23545 ST 
10 
 
5.0 RESTRICTIONS 
 
x DO NOT use for at-plant applications (e.g., hopper box, planter box). This product is to be 
applied as a water-based slurry through standard slurry- or mist-type commercial seed 
treatment equipment. 
x DO NOT apply this product in a way that will contact workers or other persons, either 
directly or through drift. 
x DO NOT use treated seed for food, feed, or oil purposes. 
x Store treated seed away from food and feedstuffs. 
x DO NOT allow children, pets, or livestock to have access to treated seed. 
x Wear long-sleeved shirt, long pants and chemical resistant gloves when handling treated 
seed. 
x Treated seed exposed on soil surface may be hazardous to wildlife. Cover or collect 
treated seed spilled during loading and planting (such as in row ends). 
x Treated seed must be planted into the soil at a depth greater than 1 inch. 
x 
x DO NOT contaminate water bodies when disposing of planting equipment washwaters. 
x Dispose of seed packaging in accordance with local requirements. 
x DO NOT apply more than 0.052 lb ai/A (23 g ai/A) per calendar year of mefenoxam- or 
metalaxyl-containing products as a seed treatment on soybean. 
x In the event of a crop failure or harvest of a crop grown from seed treated with A23545 
ST, the field may be replanted immediately to corn (field, pop, seed, or sweet) or soybean. 
For any other crop, the minimum plant-back interval is 30 days from the date the treated 
seed was planted. 
x Maximum usage when applying metalaxyl- and mefenoxam- containing products to 
the same crop within the same season: DO NOT apply more than the maximum yearly 
total application rate for the active ingredient as stated on the label of the product 
containing the lowest yearly total on that crop. 
x DO NOT apply more than 0.017 lb ai/A (7.5 g ai/A) per calendar year of picarbutrazox-
containing products as a seed treatment. 
x DO NOT apply more than 0.0167 lb ai/A (7.6 g ai/A) per calendar year of sedaxane-
containing products as a seed treatment. 
x Soybean seeds treated with this product contain 0.0038 mg fludioxonil/seed, 0.015 mg 
mefenoxam/seed, 0.0038 mg sedaxane/seed, and 0.0038 mg picarbutrazox/seed. 
x This treated seed may be planted on the same acres up to 2 times per year.

A23545 ST 
11 
 
6.0 SEED CONTAINER LABEL REQUIREMENTS 
6.1 Use of On-Farm Treated Seed (when treated seed are not 
for sale or distribution) 
Treated seed sold or distributed for a use not permitted by the following labeling does not 
qualify as an exempted treated article under 40 CFR 152.25(a) and is therefore sale or 
distribution of an unregistered pesticide, pursuant to FIFRA section 12. 
 
x Store treated seed away from food and feedstuffs. 
x DO NOT allow children, pets, or livestock to have access to treated seed. 
x Treated seed are for planting purposes only. DO NOT use for food, feed, or oil purposes. 
DO NOT use treated seed for fuel or ethanol production purposes. 
x Wear long-sleeved shirt, long pants, shoe s, socks, and chemical-resistant gloves when 
handling treated seed. 
x DO NOT plant treated seed by broadcasting to the soil surface. Ensure that all planted 
seeds are thoroughly incorporated by the planter during planting. Additional incorporation 
may be required to thoroughly cover exposed seeds. 
x Treated seed exposed on the soil surface may be hazardous to wildlife. Cover or collect 
treated seed spilled during loading and planting (such as in row ends). 
x Treated seed must be planted into the soil at a depth greater than 1 inch. 
x Manage excess treated seed (e.g., spilled, u nused, or expired treated seed) by one or 
more of the following methods: 
o Collect excess treated seed for reuse for planting. 
o Bury excess treated seed (only allowed if totaling 1 pound or less) at least 30 feet 
away from bodies of water at a depth of 6 inches or double the planting depth, 
whichever is greater. 
o Dispose of excess treated seed by plac ing them in a landfill in accordance with 
applicable laws in your state. 
o Return excess treated seed to the supplier if permitted by the state. 
x DO NOT contaminate bodies of water when disposing of equipment wash water. 
x Advisory Dust-Reducing Technique: The use of seed flow lubricants or polymer 
coatings may help decrease the amount of dust released during planting. Follow the 
recommendations of the planter manufacturer regarding the use of seed flow lubricants.

A23545 ST 
12 
 
6.2 Seed Treatment in Commercial Facilities or Seed 
Treatment on Farm (when treated seed are to be sold or 
distributed) – Seed Bag Labeling Requirements 
The Federal Seed Act requires that containers of treated seed must be labeled with the 
following statements: 
x This seed has been treated with fludioxonil, mefenoxam, picarbutrazox, and sedaxane 
fungicides. 
x DO NOT use for food, feed, or oil purposes. 
 
The U.S. Environmental Protection Agency requires that bags containing treated seed shall 
be labeled with the following statements. Any seed treated with A23545 ST that is sold or 
distributed without these statements or that is sold or distributed for a use not permitted by 
the following labeling does not qualify as an exempted treated article under 40 CFR 
152.25(a) and is therefore sale or distribution of an unregistered pesticide, pursuant to FIFRA 
section 12(a)(1)(A). 
 
This seed has been treated with A23545 ST (EPA Reg No. 100-1731) containing fludioxonil, 
mefenoxam, picarbutrazox, and sedaxane. Any seed treated with A23545 ST that is sold or 
distributed for a use not permitted by the following labeling does not qualify as an exempted 
treated article under 40 CFR 152.25(a) and is therefore sale or distribution of an unregistered 
pesticide, pursuant to FIFRA section 12(a)(1)(A). 
x The contents of this bag are for planting purposes only. DO NOT use for food, feed, or oil 
purposes. DO NOT use for fuel or ethanol production purposes. 
x Store treated seed away from food and feedstuffs. 
x DO NOT allow children, pets, or livestock to have access to treated seed. 
x Wear long-sleeved shirt, long pants and chemical resistant gloves when handling treated 
seed. 
x DO NOT plant treated seed by broadcasting to the soil surface. Ensure that all planted 
seeds are thoroughly incorporated by the planter during planting. Additional incorporation 
may be required to thoroughly cover exposed seeds. 
x Treated seed exposed on soil surface may be hazardous to wildlife. Cover or collect 
treated seed spilled during loading or planting (such as in row ends). 
x Treated seed must be planted into the soil at a depth greater than 1 inch. 
x Manage excess treated seed (e.g., spilled, unused, or expired treated seed) by one or 
more of the following methods: 
o Collect excess treated seed for reuse for planting. 
o Bury excess treated seed (only allowed if totaling 1 pound or less) at least 30 feet 
away from bodies of water at a depth of 6 inches or double the planting depth, 
whichever is greater. 
o Dispose of excess treated seed by plac ing them in a landfill in accordance with 
applicable laws in your state. 
o Return excess treated seed to the supplier if permitted by the state. 
x DO NOT contaminate water bodies when disposing of planting equipment washwaters. 
x Dispose of seed packaging in accordance with local requirements. 
x In the event of a crop failure or harvest of a crop grown from seed treated with A23545 
ST, the field may be replanted immediately to corn (field, pop, seed, or sweet) or soybean.

A23545 ST 
13 
 
For any other crop, the minimum plant-back interval is 30 days from the date the treated 
seed was planted. 
x DO NOT apply more than 0.052 lb ai/A (23 g ai/A) per calendar year of mefenoxam- or 
metalaxyl-containing products as a seed treatment. 
x Maximum usage when applying metalaxyl- and mefenoxam- containing products to 
the same crop within the same season: DO NOT apply more than the maximum yearly 
total application rate for the active ingredient as stated on the label of the product 
containing the lowest yearly total on that crop. 
x DO NOT apply more than 0.017 lb ai/A (7.5 g ai/A) of picarbutrazox-containing products 
or 0.0167 lb ai/A (7.6 g ai/A) of sedaxane-containing products per calendar year as a seed 
treatment. 
x Soybean seeds treated with this product contain 0.0038 mg fludioxonil/seed, 0.015 mg 
mefenoxam/seed, 0.0038 mg sedaxane/seed, and 0.0038 mg picarbutrazox/seed. 
x This treated seed may be planted on the same acres up to 2 times per year. 
x Groundwater Advisory: Mefenoxam is known to leach through soil into groundwater 
under certain conditions as a result of label use. Fludioxonil has properties and 
characteristics associated with chemicals detected in groundwater. These chemicals may 
leach into groundwater if used in areas where soils are permeable, particularly where the 
water table is shallow. 
x [All seed bag tags must be legible and set in at least 8-point font size.]

A23545 ST 
14 
 
7.0 SEED TREATMENT DIRECTIONS 
7.1 Soybean 
 
Target Diseases 
Use Rate 
fl oz product per 
100 lb of seed 
(fl oz product per 
140,000 seeds unit) 
grams ai per 100 kg of 
seed mg ai per seed 
 
Seed rot/pre-emergence 
damping-off, post-
emergence damping-off, 
and seedling blight caused 
by Fusarium, Pythium, and 
Rhizoctonia spp. 
Seedling root rot caused by 
Fusarium spp. 
Suppression of seed-borne 
Sclerotinia 
Seed rot and seedling blight 
caused by seed-borne 
Phomopsis spp. 
Early-season root rot 
caused by Phytophthora 
spp. 
 
2.0 
 
 
(0.933 fl oz/140,000 
seeds) 
 
2.5 g Fludioxonil 
10 g Mefenoxam 
2.5 g Picarbutrazox 
2.5 g Sedaxane 
17.5 g TOTAL 
 
0.0038 mg Fludioxonil 
0.0151 mg Mefenoxam 
0.0038 mg Picarbutrazox 
0.0038 mg Sedaxane 
0.0265 mg TOTAL 
The product rates per 100 lb seed and per 140,000 seed are based on an average seed weight of 3,000 
soybeans/lb. If treating seed with a different average seed weight, recalculate the appropriate product use 
rate. 
USE RESTRICTIONS 
x Refer to Section 6.0 for additional product use restrictions.

A23545 ST 
15 
 
8.0 STORAGE AND DISPOSAL 
STORAGE AND DISPOSAL 
Do not contaminate water, food or feed by storage or disposal. 
Pesticide Storage 
Store in original containers only. Keep container closed when not in use. Do not store near 
food or feed. In case of spill on floor or paved surfaces, mop and remove to chemical waste 
storage area until proper disposal can be made if product cannot be used according to the 
label. 
Pesticide Disposal 
Pesticide wastes are acutely hazardous. Improper disposal of excess pesticide, spray 
mixture, or rinsate is a violation of Federal Law. If these wastes cannot be disposed of by 
use according to label instructions, contact your State Pesticide or Environmental Control 
Agency, or the Hazardous Waste Representative at the nearest EPA Regional Office for 
guidance. 
Container Handling [(less than or equal to 5 gallons)] 
Non-refillable container. Do not reuse or refill this container. Triple rinse or pressure rinse 
container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the 
remaining contents into application equipment or a mix tank and drain for 10 seconds after 
the flow begins to drip. Fill the container ¼ full with water and recap. Shake for 10 seconds. 
Pour rinsate into application equipment or a mix tank or store rinsate for later use or disposal. 
Drain for 10 seconds after the flow begins to drip. Repeat this procedure two more times. 
Then offer for recycling if available, or reconditioning, or puncture and dispose of in a sanitary 
landfill, or by incineration, or by other procedures approved by state and local authorities. 
Container Handling [(greater than 5 gallons)] 
Non-refillable container. Do not reuse or refill this container. Triple rinse or pressure rinse 
container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the 
remaining contents into application equipment or a mix tank. Fill the container ¼ full with 
water. Replace and tighten closures. Tip container on its side and roll it back and forth, 
ensuring at least one complete revolution, for 30 seconds. Stand the container on its end 
and tip it back and forth several times. Turn the container over onto its other end and tip it 
back and forth several times. Empty the rinsate into application equipment or a mix tank or 
store rinsate for later use or disposal. Repeat this procedure two more times. Then offer for 
recycling if available, or reconditioning, or puncture and dispose of in a sanitary landfill, or by 
incineration, or by other procedures approved by state and local authorities. 
Container Handling [(greater than 5 gallons)] 
Refillable container. Refill this container with pesticide only. Do not reuse this container for 
any other purpose. Cleaning the container before final disposal is the responsibility of the 
person disposing of the container. Cleaning before refilling is the responsibility of the person 
refilling. To clean container before final disposal, empty the remaining contents from this 
container into application equipment or mix tank. Fill the container about 10 percent full with 
water. Agitate vigorously or recirculate water with the pump for 2 minutes. Pour or pump 
rinsate into application equipment or rinsate collection system. Repeat this rinsing procedure 
two more times. Then offer for recycling if available, or reconditioning, or puncture and 
dispose of in a sanitary landfill, or by incineration, or by other procedures approved by state 
and local authorities. 
CONTAINER IS NOT SAFE FOR FOOD, FEED, OR DRINKING WATER.

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9.0 CONDITIONS OF SALE AND LIMITATION OF WARRANTY 
AND LIABILITY 
NOTICE: Read the entire Directions for Use and Conditions of Sale and Limitation of 
Warranty and Liability before buying or using this product. If the terms are not acceptable, 
return the product at once, unopened, and the purchase price will be refunded. 
The Directions for Use of this product must be followed carefully. It is impossible to eliminate 
all risks inherently associated with the use of this product. Crop injury, ineffectiveness or 
other unintended consequences may result because of such factors as manner of use or 
application, weather or crop conditions, presence of other materials or other influencing 
factors in the use of the product, which are beyond the control of SYNGENTA CROP 
PROTECTION, LLC or Seller. To the extent permitted by applicable law, Buyer and User 
agree to hold SYNGENTA and Seller harmless for any claims relating to such factors. 
SYNGENTA warrants that this product conforms to the chemical description on the label and 
is reasonably fit for the purposes stated in the Directions for Use, subject to the inherent risks 
referred to above, when used in accordance with directions under normal use conditions. To 
the extent permitted by applicable law: (1) this warranty does not extend to the use of the 
product contrary to label instructions, or under conditions not reasonably foreseeable to or 
beyond the control of Seller or SYNGENTA, and (2) Buyer and User assume the risk of any 
such use. TO THE EXTENT PERMITTED BY APPLICABLE LAW, SYNGENTA MAKES NO 
WARRANTIES OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE 
NOR ANY OTHER EXPRESS OR IMPLIED WARRANTY EXCEPT AS WARRANTED BY 
THIS LABEL. 
To the extent permitted by applicable law, in no event shall SYNGENTA be liable for any 
incidental, consequential or special damages resulting from the use or handling of this 
product. TO THE EXTENT PERMITTED BY APPLICABLE LAW, THE EXCLUSIVE 
REMEDY OF THE USER OR BUYER, AND THE EXCLUSIVE LIABILITY OF SYNGENTA 
AND SELLER FOR ANY AND ALL CLAIMS, LOSSES, INJURIES OR DAMAGES 
(INCLUDING CLAIMS BASED ON BREACH OF WARRANTY, CONTRACT, 
NEGLIGENCE, TORT, STRICT LIABILITY OR OTHERWISE) RESULTING FROM THE 
USE OR HANDLING OF THIS PRODUCT, SHALL BE THE RETURN OF THE PURCHASE 
PRICE OF THE PRODUCT OR, AT THE ELECTION OF SYNGENTA OR SELLER, THE 
REPLACEMENT OF THE PRODUCT. 
SYNGENTA and Seller offer this product, and Buyer and User accept it, subject to the 
foregoing Conditions of Sale and Limitation of Warranty and Liability, which may not be 
modified except by written agreement signed by a duly authorized representative of 
SYNGENTA. 
 
Cruiser
®, Fortenza®, Saltro®, Vayantis®, the ALLIANCE FRAME 
the SYNGENTA Logo, and the PURPOSE ICON 
are Trademarks of a Syngenta Group Company 
 
Viton™ is a trademark of The Chemours Company FC, LLC 
 
© 20XX Syngenta

A23545 ST 
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For non-emergency (e.g., current product information), call 
Syngenta Crop Protection at 1-866-796-4368. 
 
 
 
Manufactured for: 
Syngenta Crop Protection, LLC 
P.O. Box 18300 
Greensboro, North Carolina 27419-8300 
 
 
 
A23545 ST 1731 MAS 0323 AMEND-B 0226 – CL – jeb – 05/22/2026 
000100-01731.20260216B.A23545_ST_AMEND_FEB2026-CL.pdf