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# TOPSIN M WSB
- EPA Reg No: **8033-125**
- Registrant: NIPPON SODA CO., LTD.
- Signal word: Caution
- Active ingredients: Thiophanate-methyl (70%)
- Label accepted: 2026-06-25
- Source PDF: https://www3.epa.gov/pesticides/chem_search/ppls/008033-00125-20260625.pdf
---
June 25, 2026
Pedro Perdomo
Senior Registration Specialist
Nisso America
379 Thornall St., 5th Floor
Edison, NJ 08837
p.perdomo@nissoamerica.com
Subject: Label Amendment - Registration Review Mitigation for Thiophanate-methyl
Product Name: TOPSIN M WSB
EPA Registration Number: 8033-125
Case Number: 675269
Application Date: March 6, 2025
Dear Pedro Perdomo,
The Agency, in accordance with the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA),
as amended, has completed reviewing all the information submitted with your application to
support the Registration Review of the above referenced product in connection with the
Thiophanate-methyl Interim Decision, and has concluded that your submission is acceptable.
The label referred to above, submitted in connection with registration under FIFRA, as
amended, is acceptable.
Should you wish to add/retain a reference to the company’s website on your label, then please
be aware that the website becomes labeling under the Federal Insecticide, Fungicide, and
Rodenticide Act and is subject to review by the Agency. If the website is false or misleading, the
product would be misbranded and unlawful to sell or distribute under FIFRA section 12(a)(1)(E).
40 CFR 156.10(a)(5) list examples of statements EPA may consider false or misleading. In
addition, regardless of whether a website is referenced on your product’s label, claims made on
the website may not substantially differ from those claims approved through the registration
process. Therefore, should the Agency find or if it is brought to our attention that a website
contains false or misleading statements or claims substantially differing from the EPA approved
registration, the website will be referred to the EPA’s Office of Enforcement and Compliance
Assurance.
A stamped copy of your labeling is enclosed for your records. This labeling supersedes
all previously accepted labeling and must be used at your next label printing. You must
Page 2 of 2
EPA Reg. No. 8033-125
Case No. 675269
submit one copy of the final printed labeling before you release the product for
shipment with the new labeling. In accordance with 40 CFR 152.130(c), you may
distribute or sell this product under the previously approved labeling for 12 months
from the date of this letter. After 12 months, you may only distribute or sell this
product if it bears this new revised labeling or subsequently approved labeling. “To
distribute or sell” is defined under FIFRA section 2(gg) and its implementing regulation
at 40 CFR 152.3.
If you have any questions about this letter, please contact Alex McKee by phone at 202-566-
1939, or via email at mckee.alex@epa.gov.
Sincerely,
Dana L. Friedman, Chief
Risk Management and Implementation Branch 1
Pesticide Re-Evaluation Division
Office of Pesticide Programs
U.S. Environmental Protection Agency
ENCLOSURE: Stamped label
Clean Draft Label 2-14-25 EPA edits 5.18.26 6.10.26 6.17.26
Label Updates and Mitigation Additions
Page 1 of 41
1
THIOPHANATE-METHYL GROUP 1 FUNGICIDE
TOPSIN® M WSB
THIOPHANATE-METHYL FUNGICIDE
IN WATER SOLUBLE BAGS
70% Wettable Powder
ACTIVE INGREDIENT:
Thiophanate-methyl (dimethyl [(1,2-phenylene)-
bis(iminocarbonothioyl)]bis[carbamate])*………………………………………..……….70.0%
OTHER INGREDIENTS:…………………………………………………….....................30.0%
TOTAL………………………….……….100.0%
*Also known as dimethyl 4 4'-o-phenylenebis[3-thioallophanate]
KEEP OUT OF REACH OF CHILDREN
CAUTION
FIRST AID
If on skin or clothing:
x Take off contaminated clothing.
x Rinse skin immediately with plenty of water for 15-20 minutes.
x Call a poison control center or doctor for treatment advice.
If inhaled:
x Move person to fresh air.
x If person is not breathing, call 911 or an ambulance, then give artificial respiration,
preferably mouth-to-mouth if possible.
x Call a poison control center or doctor for further treatment advice.
If in eyes:
x Hold eye open and rinse slowly and gently with water for 15-20 minutes.
x Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye.
x Call a poison control center or doctor for treatment advice.
Have the product container or label with you when calling a poison control center or doctor or
going for treatment. Contact the Rocky Mountain Poison Control Center at 1-866-767-5089
for emergency medical treatment information.
EPA Registration No. 8033-125 EPA Establishment No.
NET WEIGHT: _________ Pounds (_________ Kgs.) Batch/Lot No. _________________
Nippon Soda Co., Ltd.,
c/o Nisso America Inc.
379 Thornall Street, 5
th Floor
Edison, NJ 08837
Jun 25, 2026
8033-125
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PRECAUTIONARY STATEMENTS
HAZARDS TO HUMANS AND DOMESTIC ANIMALS
CAUTION: HARMFUL IF ABSORBED THROUGH SKIN OR INHALED. AVOID
BREATHING DUST OR SPRAY MIST. CAUSES MODERATE EYE IRRITATION. AVOID
CONTACT WITH SKIN, EYES, OR CLOTHING. WASH HANDS BEFORE EATING,
DRINKING, CHEWING GUM, USING TOBACCO PRODUCTS, OR USING THE TOILET.
PERSONAL PROTECTIVE EQUIPMENT (PPE)
All private handlers and applicators making foliar applications must wear double layer clothing
and gloves.
Mixers, loaders, applicators, and other handlers supporting dip treatment must wear:
x Coveralls over long-sleeved shirt and long pants,
x Chemical-resistant gloves,
x Chemical-resistant footwear plus socks,
x Chemical-resistant apron.
All other mixers, loaders, applicators, and handlers must wear:
x Long-sleeved shirt and long pants,
x Shoes plus socks,
x Chemical resistant gloves
All mixers, loaders, and applicators using MPH for DF/WDG, liquid, and WSP formulations of
TM on typical field crops, orchards, and vineyards must wear double layer clothing and gloves.
Some materials that are chemical-resistant to this product are barrier laminate, butyl rubber
•PLOV QLWULOHUXEEHU•PLOVQHRSUHQHUXEEHU•PLOV SRO\YLQ\OFKORULGH 39& •PLOV
DQGYLWRQ•PLOV
See engineering controls for additional requirements.
USER SAFETY REQUIREMENTS
Follow manufacturer’s instructions for cleaning/maintaining PPE. If no such instructions for
washables exist, use detergent and hot water. Keep and wash PPE separately from other
laundry. Discard clothing and other absorbent materials that have been drenched or heavily
contaminated with this product’s concentrate. DO NOT reuse them.
ENGINEERING CONTROLS
Water soluble packets when used correctly qualify as a closed mixing/loading system under the
Worker Protection Standard [40 CFR 170. 607(d)].
Mixers and loaders handling this product while it is enclosed in intact water-soluble packets may
elect to wear reduced PPE of long-sleeved shirt, long pants, shoes, socks. When reduced PPE is
worn because a closed system is being used, handlers must be provided all PPE specified above
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for “applicators and other handlers” and have such PPE immediately available for use in an
emergency, for example a spill or equipment break-down.
When handlers use enclosed cabs in a manner that meets the requirements listed in the Worker
Protection Standard (WPS) for agricultural pesticides [40 CFR 170.607(d-f)], the handler PPE
requirements may be reduced or modified as specified in the WPS.
USER SAFETY RECOMMENDATIONS
ƔUsers should remove clothing/PPE immediately if pesticide gets inside. Then wash
thoroughly and put on clean clothing.
ƔUsers should remove PPE immediately after handling this product. Wash the outside of
gloves before removing. As soon as possible, wash thoroughly and change into clean
clothing.
ENVIRONMENTAL HAZARDS
For terrestrial uses: DO NOT apply directly to water or areas where surface water is present
or to intertidal areas below the mean high water mark. Runoff from treated areas may be
hazardous to aquatic organisms in neighboring areas. DO NOT contaminate water when
disposing of equipment washwater or rinsate.
DO NOT apply during rain.
Pollinator Hazard Statement
This product is moderately toxic to bees and other pollinating non-target insects exposed to
direct treatment on blooming crops or weeds.
DIRECTIONS FOR USE
ENDANGERED AND THREATENED SPECIES PROTECTION REQUIREMENTS: Before
using this product, you must obtain any applicable Endangered Species Protection Bulletins
(‘Bulletins’) within six months prior to or on the day of application. To obtain Bulletins, go to
Bulletins Live! Two (BLT) at https://www.epa.gov/pesticides/bulletins. When using this product, you
must follow all directions and restrictions contained in any applicable Bulletin(s) for the area where
you are applying the product, including any restrictions on application timing if applicable. It is a
violation of Federal law to use this product in a manner inconsistent with its labeling, including this
labeling instruction to follow all directions and restrictions contained in any applicable Bulletin(s). For
general questions or technical help, call 1-844-447-3813, or email ESPP@epa.gov.
REPORTING ECOLOGICAL INCIDENTS: For guidance on reporting ecological incidents,
including death, injury, or harm to plants and animals, including bees and other non-target insects, see
EPA’s Pesticide Incident Reporting website: https://www.epa.gov/pesticide-incidents or call Nippon
Soda Co., Ltd. at 212-490-0350.
It is a violation of Federal law to use this product in a manner inconsistent with its labeling.
DO NOT apply this product in a way that will contact workers or other persons, either directly
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or through drift. Only protected handlers may be in the area during application. For any
requirements specific to your State or Tribe, consult the agency responsible for pesticide
regulation.
DO NOT apply when wind speed favors drift beyond the area intended for treatment.
DO NOT apply TOPSIN® M WSB where the texture of the underlying (native) soil, is sand or
loamy sand, the depth to groundwater is 20 feet or less, and the soil has less than 2% organic
matter.
AGRICULTURAL USE REQUIREMENTS
Use this product only in accordance with its labeling and with the Worker Protection Standard,
40 CFR part 170. This Standard contains requirements for the protection of agricultural
workers on farms, forests, nurseries, and greenhouses, and handlers of agricultural pesticides.
It contains requirements for training, decontamination, notification, and emergency assistance.
It also contains specific instructions and exceptions pertaining to the statements on this label
about personal protective equipment (PPE), and restricted-entry interval. The requirements in
this box only apply to uses of this product that are covered by the Worker Protection Standard.
DO NOT enter or allow worker entry into treated areas during the restricted entry interval
(REI). The Restricted Entry Interval (REI) is 12 hours except as listed in the application rate
tables below.
PPE required for early entry to treated areas that is permitted under the Worker Protection
Standard and that involves contact with anything that has been treated, including plants, soil,
or water, is:
x Coveralls over long-sleeved shirt and long pants,
x Chemical-resistant gloves,
x Chemical-resistant footwear plus socks,
x Chemical-resistant headgear for overhead exposures.
PRODUCT INFORMATION
Apply Topsin M WSB with ground or aerial equipment, using sufficient volume of spray to
provide thorough coverage. Add required amount of Topsin M WSB to partially filled tank
agitated by mechanical or hydraulic means, and then add remaining required amount of water.
Continuous agitation is required to keep the material in suspension.
Topsin M WSB may be tank-mixed with fungicides, insecticides and/or plant growth regulators
that are approved for use on the intended crop. Tank mixes with highly alkaline pesticides, for
example Bordeaux mixture or lime sulfur are not directed. No claim of compatibility with other
pesticides is implied. It is directed to perform a Compatibility Jar Test to ensure tank mix
product compatibility prior to use. See Compatibility Test section of this label for more
information.
Begin applications as disease is first observed or expected. Tank mixing with a protectant
fungicide is directed for resistance management. Use the higher rate under conditions of severe
disease pressure. Also, see local State Extension Service directions for application schedules.
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Aerial Applications. Use a minimum of 5 gallons of spray volume per acre for row crops, and a
minimum of 10 gallons of spray volume per acre for tree crops.
Ground Applications. Use a minimum of 10 to 20 gallons of spray volume per acre for row
crops.
High Volume Dilute Applications. Use the Topsin M WSB per acre use rate for concentrate
spray application for tree crops (no more than 400 gallons on apples and pears; or 300 gallons on
stone fruit). When making dilute ground application, use Topsin M WSB use rate per 100
gallons. Follow all crop specific application language on this label.
Higher spray volumes will result in better coverage and better disease control. Lack of control
when using below minimum spray volumes is solely at the risk of the applicator/user. This
includes the use of electrostatic sprayers.
Chemigation. Please see DIRECTIONS FOR USE THROUGH CHEMIGATION SYSTEMS
for specific information. DO NOT apply through any irrigation system unless these instructions
are followed.
Topsin M WSB may be used for control of labeled diseases during the non-bearing years of new
planting of tree fruit and tree nuts, and on nursery stock.
Plantback restrictions: DO NOT plant any crop not labeled for Topsin use within 30 days of last
application.
Topsin M WSB has protectant, systemic and curative actions, each specific to certain crops,
fungi and climatic conditions.
Instructions for Introducing Water Soluble Packages Directly into Spray tanks:
Topsin M WSB consists of a protective outer resealable package containing water-soluble bags.
Water Soluble Packages (WSPs) are designed to dissolve in water. Agitation may be used, if
necessary, to help dissolve the WSP. Failure to follow handling and mixing instructions can
increase your exposure to the pesticide products in WSPs. WSPs, when used properly, qualify as
a closed mixing/loading system under the Agricultural Worker Protection Standard [40 CFR
170.607(d)].
It is the pesticide user's responsibility to ensure that all products are registered for the intended
use. Read and follow the applicable restrictions and limitations and directions for use on all
product labels involved in tank mixing. Users must follow the most restrictive directions for use
and precautionary statements of each product in the tank mixture.
Handling Instructions
Follow these steps when handling pesticide products in WSPs.
1. Mix in spray tank only.
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2. Handle WSP in a manner that protects package from breakage and/or unintended release of
contents. If package is broken, put on PPE required for clean-up and then continue with
mixing instructions.
3. Keep the WSP in outer packaging until just before use.
4. Keep the WSP dry prior to adding to the spray tank.
5. Handle with dry gloves and according to the label instructions for PPE.
6. Keep WSP intact. DO NOT cut or puncture WSP.
7. Reseal the WSP outer packaging to protect any unused WSP(s).
Mixing Instructions
Follow the steps below when mixing this product, including if tank mixed with other pesticide
products. If being tank mixed, the mixing directions 1 through 9 below take precedence over the
mixing directions of the other tank mix products. WSPs may, in some cases, be mixed with other
pesticide products so long as the directions for use of all pesticide product components do not
conflict. DO NOT tank mix this product with products that prohibit tank mixing or have
conflicting mixing directions.
1. If a basket or strainer is present in the tank hatch, remove prior to adding the WSP to the
tank.
2. Fill tank with water to approximately one-third to one-half of the desired final volume of
spray.
3. Stop adding water and stop any agitation.
4. Place intact/unopened WSP into the tank.
5. DO NOT spray water from a hose or fill pipe to break or dissolve the WSP.
6. Start mechanical and recirculation agitation from the bottom of tank without using any
overhead recirculation, if possible. If overhead recirculation cannot be turned off, close the
hatch before starting agitation.
7. Dissolving the WSP may take up to 5 minutes or longer, depending on water temperature,
water hardness and intensity of agitation.
8. Stop agitation before tank lid is opened.
9. Open the lid to the tank, exercising caution to avoid contact with dusts or spray mix, to verify
that the WSP has fully dissolved and the contents have been thoroughly mixed into the
solution.
10. DO NOT add other allowed products or complete filling the tank until the bags have fully
dissolved and pesticide is thoroughly mixed.
11. Once the WSP has fully dissolved and any other products have been added to the tank,
resume filling the tank with water to the desired level, close the tank lid, and resume
agitation.
12. Use the spray solution when mixing is complete.
13. Maintain agitation of the diluted pesticide mix during transport and application.
14. It is unlawful to use any registered pesticide, including WSPs, in a manner inconsistent with
its label.
DO NOT mix more spray volume than will be applied that day.
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CONVERSION TABLE
ACRES TREATED PER 1 LB WATER SOLUBLE BAG
LABEL USE RATE
LBS./A TOPSIN M WSB (lb a.i./A)
ACRES TREATED WITH
ONE WATER SOLUBLE BAG
½ LB (0.35) 2.0
1 LB (0.7) 1.0
2 LB (1.4) 0.5
CONVERSION TABLE
ACRES TREATED PER 2.5 LB WATER SOLUBLE BAG
LABEL USE RATE
LBS./A TOPSIN M WSB (lb a.i./A)
ACRES TREATED WITH
ONE WATER SOLUBLE BAG
½ LB (0.35) 5
1 LB (0.7) 2.5
2 LB (1.4) 1.25
Compatibility Test for Mix Components
It is directed a Compatibility Jar Test be conducted for uncertainty of tank mix products. For 20
gallons per acre spray volume, use 3.3 cups of water from intended source. Add components in
the sequence indicated above in Mixing Instructions using 2 teaspoons for each pound or 1
teaspoon for each pint of specified label rate per acre. Tightly replace cap on the jar and invert
10 cycles between component additions.
When all tank mix products have been added to the jar and properly mixed, let sit for 15 minutes.
Evaluate the solution for uniformity and stability. The mixed spray solution should not have
fine particles on the bottom, nor a thick texture, nor free oil on the surface. If tank mix partners
are not compatible, test with the addition of a suitable compatibility agent.
USE RESTRICTIONS
WATER PROTECTION STATEMENT
x DO NOT apply during rain.
MANDATORY RUNOFF MITIGATION
Runoff mitigation is required for this product unless certain field/application parameters are
present at the time of application (i.e., subsurface or tile drains with controlled outlet, perimeter
berm systems, irrigation tailwater return systems, spot treatment, etc). Access EPA’s Mitigation
Menu Website at www.epa.gov/pesticides/mitigation-menu for a full list of field/application
parameters to evaluate whether your field is subject to runoff mitigation.
If the application does not meet the specified field/application parameters, a minimum of one
point for the crop uses listed on this label must be achieved. The applicator must choose among
the mitigation and/or mitigation relief measures on EPA’s Mitigation Menu Website to meet or
exceed these points before applying this product. The website includes the full menu of runoff
mitigation and mitigation relief measures. The following are examples:
o Location in a very low, low, or medium runoff vulnerability county
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o Field slope
o Soil incorporation
o Conservation tillage
o Vegetative strips
o Cover crop or continuous ground cover
o Irrigation water management
o Mulching
o Grassed waterway
o Vegetated ditch
o Constructed and natural wetlands
o Water retention systems
o Following recommendations from a runoff specialist or participating in a qualifying
conservation program (see www.epa.gov/pesticides/mitigation-menu for minimum
elements).
To achieve mitigation points for the application, the mitigation and mitigation relief
measures must be:
• Employed in accordance with the instructions and descriptions on EPA’s
Mitigation Menu Website.
• In place during the application unless a different timing (such as before or after
application) is specifically provided in the measure’s description on EPA’s
Mitigation Menu Website.
EPA may periodically update the Mitigation Menu Website, for example, by adding new
mitigation measures or updating a mitigation measure description.
When tank mixing, the most restrictive of the products’ labeling requirements must be
followed (e.g., use prohibition, timing restriction, application method restriction, sandy
soil application restriction). Check Bulletins Live Two! for additional restrictions that
may be applicable for your application site. If bulletins are applicable, follow the strictest
requirements between the labels and bulletins.
MANDATORY SPRAY DRIFT MANAGEMENT
Aerial Applications:
• DO NOT release spray at a height greater than 10 ft above the ground or vegetative canopy
unless a greater application height is necessary for pilot safety.
• Applicators must select nozzle and pressure that deliver medium or coarser droplets in
accordance with American Society of Agricultural & Biological Engineers Standard 641
(ASABE S641).
• During application, the Sustained Wind Speed, as defined by the National Weather Service
(standard averaging period of 2 minutes) must register between 3 and 15 miles per hour.
• Wind speed and direction must be measured on location using a windsock, an anemometer
(including systems to measure wind speed or velocity on an aircraft), or an aircraft smoke
system.
• Wind speed must be measured at the release height or higher, in an area free from obstructions
such as trees, buildings, and farm equipment.
• If the wind speed is 10 miles per hour or less, applicators must use a minimum of ½ swath
displacement upwind at the downwind edge of the field. When the wind speed is between 11-15
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miles per hour, applicators must use a minimum of ¾ swath displacement upwind at the
downwind edge of the field.
• When the wind speed is between 11-15 miles per hour, the boom length must be 65% or less of
the wingspan for fixed wing aircraft and 75% or less of the rotor diameter for helicopters.
Otherwise, the boom length must be 75% or less of the wingspan for fixed-wing aircraft and
90% or less of the rotor diameter for helicopters.
• DO NOT apply during temperature inversions.
Spray Drift Buffer to Aquatic Habitats
• DO NOT apply within 50 feet of aquatic habitats (such as, but not limited to, lakes, reservoirs,
rivers, permanent streams or ephemeral streams when water is present, wetlands or natural
ponds, estuaries, and commercial fish farm ponds) when wind is blowing toward the aquatic
habitat. On-farm irrigation ditches, irrigation canals, other on-farm water conveyances, and
irrigation management structures such as tailwater collection ponds are not considered aquatic
habitat. Any land between the aquatic habitat and the application area can be included in the
buffer (including Conservation Reserve Program (CRP) and Agricultural Conservation Easement
Program (ACEP) areas).
A 50% reduction in the required wind-directional buffer distance can be made if a windbreak or
shelterbelt (e.g., trees or riparian hedgerows) between the application site and aquatic habitat is
present and meets the criteria listed in the ‘Windbreak-Shelterbelt Criteria’ section of this label.
Spray Drift Buffer to Wildlife Conservation Areas
• DO NOT apply within 50 feet of any conservation areas when wind is blowing toward the
conservation area. Conservation areas include public lands and parks, national and state
wilderness areas and wildlife refuges, national and state forests, and national and state
grasslands. Any land between the conservation areas and the application area can be included in
the buffer (including Conservation Reserve Program (CRP) and Agricultural Conservation
Easement Program (ACEP) areas). Applications made to agricultural fields located within a
conservation area are acceptable when made in accordance with an approved pesticide
management plan for the conservation area and the restrictions on this label.
A 50% reduction in the required wind-directional buffer distance can be made if a windbreak or
shelterbelt (e.g., trees or riparian hedgerows) between the application site and conservation area
is present and meets the criteria listed in the ‘Windbreak-Shelterbelt Criteria’ section of this
label.
MANDATORY SPRAY DRIFT MANAGEMENT
Ground Boom Applications:
• During application, the Sustained Wind Speed, as defined by the National Weather Service
(standard averaging period of 2 minutes), must register between 3 and 15 miles per hour.
• Wind speed and direction must be measured on location using a windsock or anemometer
(including systems to measure wind speed or velocity using application equipment).
• Wind speed must be measured at the release height or higher, in an area free from obstructions
such as trees, buildings, and farm equipment.
• DO NOT release spray at a height greater than 3 feet above the ground or crop canopy.
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• Applicators must select nozzle and pressure that deliver medium or coarser droplets in
accordance with American Society of Agricultural & Biological Engineers Standard 572.3
(ASABE S572.3).
• DO NOT apply during temperature inversions.
Spray Drift Buffer to Aquatic Habitats
• DO NOT apply within 15 feet of aquatic habitats (such as, but not limited to, lakes, reservoirs,
rivers, permanent streams or ephemeral streams when water is present, wetlands or natural
ponds, estuaries, and commercial fish farm ponds) when wind is blowing toward the aquatic
habitat. On-farm irrigation ditches, irrigation canals, other on-farm water conveyances, and
irrigation management structures such as tailwater collection ponds are not considered aquatic
habitat. Any land between the aquatic habitat and the application area can be included in the
buffer (including Conservation Reserve Program (CRP) and Agricultural Conservation Easement
Program (ACEP) areas).
A 50% reduction in buffer distance can be made if:
o the application is made with a hooded sprayer; or,
o a windbreak or shelterbelt (e.g., trees or riparian hedgerows) between the application
site and aquatic habitat is present and meets the criteria listed in the ‘Windbreak-
Shelterbelt Criteria’ section of this label.
A 75% reduction in buffer distance can be made if a hooded sprayer is used and a downwind
windbreak is present and higher than the release height.
Spray Drift Buffer to Wildlife Conservation Areas
• DO NOT apply within 15 feet of any conservation areas when wind is blowing toward
the conservation area. Conservation areas include public lands and parks, national and state
wilderness areas and wildlife refuges, national and state forests, and national and state
grasslands. Any land between the conservation areas and the application area can be included in
the buffer (including Conservation Reserve Program (CRP) and Agricultural Conservation
Easement Program (ACEP) areas). Applications made to agricultural fields located within a
conservation area are acceptable when made in accordance with an approved pesticide
management plan for the conservation area and the restrictions on this label. A 50% reduction in
buffer distance can be made if:
o the application is made with a hooded sprayer; or,
o a windbreak or shelterbelt (e.g., trees or riparian hedgerows) between the application
site and conservation area is present and meets the criteria listed in the ‘Windbreak-
Shelterbelt Criteria’ section of this label.
A 75% reduction in buffer distance can be made if a hooded sprayer is used and a downwind
windbreak is present and higher than the release height.
Boom-less Ground Applications:
Setting nozzles at the lowest effective height will help to reduce the potential for spray drift.
-Applicators are required to use a medium or coarser spray droplet size (ASABE S572.1) for all
applications.
-Do not apply when wind speeds exceed 10 miles per hour at the application site.
-Do not apply during temperature inversions.
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Windbreak-Shelterbelt Criteria
A 50% reduction in the wind-directional buffer distance required above can be made if a
windbreak or shelterbelt (e.g., trees or riparian hedgerows) between the application site and
aquatic habitat/conservation area is present and meets the following criteria:
• The windbreak or shelterbelt must be downwind between the pesticide application and the
aquatic habitat/conservation area.
• The windbreak or shelterbelt must have a minimum of one row of trees and/or shrubs that have
foliage that is sufficiently dense such that the aquatic habitat/conservation area is not visible on
the upwind side at the time of application.
• The row(s) of trees and/or shrubs in the windbreak/shelterbelt must run the full length of the
treated crop and must have foliage that is sufficiently dense such that the aquatic
habitat/conservation area is not visible on the upwind side.
• The height of the trees in the windbreak or shelterbelt must be at the same height or higher than
the release height of the application.
• The windbreak or shelterbelt must be planted according to local/regional/federal conservation
program standards; however, no state or federally listed noxious or invasive trees or shrubs
should be planted.
• The windbreak or shelterbelt must be maintained such that its functionality is not compromised.
A semi-permeable manmade structure, curtain, or netting that is raised prior to application can be
used instead of a windbreak or shelterbelt. This structure must be downwind between the
pesticide application and the non-managed area, cover the entire distance of field adjacent to
non-managed area, and at the same height or higher as the release height of the application.
SPRAY DRIFT ADVISORIES
THE APPLICATOR IS RESPONSIBLE FOR AVOIDING OFF-SITE SPRAY DRIFT. Be
aware of nearby non-target sites and environmental conditions.
IMPORTANCE OF DROPLET SIZE
An effective way to reduce spray drift is to apply large droplets. Use the largest droplets that
provide target pest control. While applying larger droplets will reduce spray drift, the potential
for drift will be greater if applications are made improperly or under unfavorable environmental
conditions.
Controlling Droplet Size - Ground Boom
x Volume - Increasing the spray volume so that larger droplets are produced will reduce
spray drift. Use the highest practical spray volume for the application. If a greater spray volume
is needed, consider using a nozzle with a higher flow rate.
x Pressure - Use the lowest spray pressure recommended for the nozzle to produce the
target spray volume and droplet size.
x Spray Nozzle - Use a spray nozzle that is designed for the intended application. Consider
using nozzles designed to reduce drift.
Controlling Droplet Size - Aircraft
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12
ƒ Adjust Nozzles - Follow nozzle manufacturers’ recommendations for setting up nozzles.
Generally, to reduce fine droplets, nozzles should be oriented parallel with the airflow in flight.
BOOM HEIGHT - Ground Boom
For ground equipment, the boom should remain level with the crop and have minimal bounce.
RELEASE HEIGHT - Aircraft
Higher release heights increase the potential for spray drift.
HOODED (OR SHIELDED) SPRAYERS
Shielding the boom or individual nozzles can reduce spray drift. Consider using hooded sprayers.
Verify that the shields are not interfering with the uniform deposition of the spray on the target
area.
TEMPERATURE AND HUMIDITY
When making applications in hot and dry conditions, use larger droplets to reduce effects of
evaporation.
TEMPERATURE INVERSIONS
Drift potential is high during a temperature inversion. Temperature inversions are characterized
by increasing temperature with altitude and are common on nights with limited cloud cover and
light to no wind. The presence of an inversion can be indicated by ground fog or by the
movement of smoke from a ground source or an aircraft smoke generator. Smoke that layers and
moves laterally in a concentrated cloud (under low wind conditions) indicates an inversion, while
smoke that moves upward and rapidly dissipates indicates good vertical air mixing. Avoid
applications during temperature inversions.
WIND
Drift potential generally increases with wind speed.
Applicators need to be familiar with local wind patterns and terrain that could affect spray drift.
MEASURING WIND SPEED AND WIND DIRECTION
Best Management Practices for measuring wind speed and direction of wind:
• Applicators should check and acquire the predicted wind speed and direction for the application
site within 12 hours prior to conducting applications to determine the time periods wind speed is
likely to fall outside the applicable thresholds.
• Applicators should reassess wind speed and direction at the application site every 15 minutes
while applications are in progress.
• Measuring wind speed and direction can be done by:
o Relying on the application equipment that measures wind speed (e.g., aerial
equipment).
o Using a tower anemometer with telemetry or handheld anemometer. Users should
read user manual on how to calibrate, operate and interpret the output from an
anemometer. Ground applicators should stop every 15 minutes to take a reading with a
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13
tower anemometer with telemetry or handheld anemometer. Some anemometers may
have software that would allow users to view wind measurements in real time while
making an application, and, in those cases, applicators would not have to stop to take
measurements.
o Using a windsock. Wind can be estimated with a windsock using the stripes on a
windsock. The applicator should consult the user manual for the windsock on wind
speed estimation and direction of wind. Applicators should look at the sock at least
every 15 minutes to estimate wind speed and direction. The windsock should be pointed
in the opposite
direction of the windbreak and CONSERVATION AREA/AQUATIC HABITAT.
o Using an aircraft smoke system. Laying down several puffs of smoke along different
lines using an aircraft smoke system can provide an accurate view of the wind
speed and direction for the application.
o Checking behind the spray rig at least every 15 minutes to see if the spray has changed
direction from when the application started.
Handheld Technology Applications:
• Take precautions to minimize spray drift.
RESISTANCE MANAGEMENT:
For resistance management, Topsin M WSB contains a Group 1 fungicide. Any fungal
population may contain individuals naturally resistant to Topsin M WSB and other Group 1
fungicides. A gradual or total loss of pest control may occur over time if these fungicides are
used repeatedly in the same fields. Appropriate resistance-management strategies should be
followed.
To delay fungicide resistance, take one or more of the following steps:
• Rotate the use of Topsin M WSB Fungicide or other Group 1 fungicides within a growing
season sequence with different groups that control the same pathogens.
• Use tank mixtures with fungicides from a different group that are equally effective on the target
pest when such use is permitted. Use at least the minimum application rate as labeled by the
manufacturer.
• Adopt an integrated disease management program for fungicide use that includes scouting, uses
historical information related to pesticide use, and crop rotation, and which considers host plant
resistance, impact of environmental conditions on disease development, disease thresholds, as
well as cultural, biological and other chemical control practices.
• Where possible, make use of predictive disease models to effectively time fungicide
applications. Note that using predictive models alone is not sufficient to manage resistance.
• Monitor treated fungal populations for resistance development.
• Contact your local extension specialist or certified crop advisor for any additional pesticide
resistance-management and/or IPM recommendations for specific crops and pathogens.
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14
• For further information or to report suspected resistance contact Nippon Soda Co., Ltd. at 212-
490-0350. You can also contact your pesticide distributor or university extension specialist to
report resistance.
Advisory Best Management Practices for Pollinator Protection
The following best management practices (BMPs) can help reduce risk to pollinators:
• Develop and maintain clear communication with local beekeepers to help protect bees. To the
extent possible, advise beekeepers within a 1-mile radius 48-hrs in advance of the application,
and confirm hive locations before spraying.
• Avoid applications when bees are actively foraging.
• Avoid applying pesticides to plants in bloom, including flowering weeds.
• Apply pesticides in the evening or at night when fewer bees are foraging.
• Use Pollinator Protection Plans when they are available. These plans may be available from
state lead agencies and promote communication between growers, landowners, farmers,
beekeepers, pesticide users, and other pest management professionals to reduce exposure of bees
and other pollinators to pesticides.
• Use integrated pest management to prevent or mitigate potential negative effects to pollinators
and consider multiple pest management options before resorting to a pesticide application.
• Mowing understory weeds or cover crops in orchards and vineyards before blooming can
prevent flowering of weeds and reduce exposure to bees where and when pesticides are applied.
The following BMPs can help promote the health and habitat of ground-nesting bees:
• For uncultivated land, leaving large undisturbed patches of land un-mowed and untilled can
provide nesting and forage sites.
• For uncultivated land, mowing at the highest cutting height possible (minimum of 8-10 inches
if possible) can increase and diversify food sources.
For additional resources on pollinator BMPs and Pollinator Protection Plans, visit
https://www.epa.gov/pollinator-protection/find-best-management-practices-protect-pollinators.
CROP SPECIFIC INFORMATION.
Follow resistance management guidelines as outlined in this label.
Crop
Diseases
Lbs
product/
Acre (lb
a.i./A)
Lb/100
Gal (lb
a.i./100
gal)
Application Instructions
Almonds
Brown Rot
Blossom Blight
(Monilinia)
Scab
(Cladosporium)
Jacket Rot
(Monilinia,
Sclerotinia,
Botrytis)
Leaf Blight
1 - 1½ lbs/A
(0.7 – 1.05)
Apply as needed at 10 to 14-day
intervals between pink bud and petal
fall. Apply alone at pink bud for
Brown Rot control. For all other
applications, apply with a contact
fungicide including Ziram 76DF
(EPA Reg. No. 70506-173, ziram) or
Manzate Pro-Stick (EPA Reg. No.
70506-234, mancozeb) for broad-
spectrum control and resistance
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15
Crop
Diseases
Lbs
product/
Acre (lb
a.i./A)
Lb/100
Gal (lb
a.i./100
gal)
Application Instructions
(Seimatosporium) management.
Restrictions:
-DO NOT apply more than 1 ½ lb/A
(1.05 lb ai/A) per application.
-DO NOT apply more than 3.0 lb of
product (2.1 lbs a.i.)/A/year.
-The minimum retreatment interval
is ten (10) days.
-DO NOT apply more than three (3)
applications per year.
-DO NOT enter or allow worker
entry into treated areas during the
restricted entry interval (REI) of 3
days
Apples
Apple Scab
(Venturia)
Black Pox*
(Helminthosporium
papulosum)
Flyspeck
(Zygophiala)
Powdery Mildew
(Podosphaera)
Sooty Blotch
(Gloeodes)
Black Rot
(Botryosphaeria
obtusa)
Brooks Fruit Spot
(Mycosphaerella)
White Rot*
(Botryosphaeria
dothidia)
* Not for use in
California.
¾ - 1 lbs/A
(0.53 – 0.7)
(In
California:
1½ lbs/A
(1.05))
1/5-1/4
lbs/100
gal.
(0.15 –
0.18)
Apply at 5 to 10-day intervals from
green tip through petal fall; continue
at 7 to 14-day intervals in cover
sprays.
Restrictions:
-DO NOT apply more than 1.0 lb/A
(0.7 lb ai/A) per application.
-In California, DO NOT apply more
than 1.5 lb/A (1.05 lb ai/A) per
application.
- DO NOT apply more than 4.0 lb of
product (2.8 lbs a.i.)/A/year.
-The minimum retreatment interval
is five (5) days.
- DO NOT apply more than five (5)
applications per year.
- DO NOT enter or allow worker
entry into treated areas during the
restricted entry interval (REI) of 2
days
-PHI: 1 day
Use to Control Development of Diseases on Apples Following Harvest
Storage Rot
Blue Mold
(Penicillium
expansum)
1 lb/A
(0.7)
Apply as a pre-harvest spray within
2 weeks to 3 days of harvest.
Thorough coverage of the fruit is
required. Application closer to
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16
Crop
Diseases
Lbs
product/
Acre (lb
a.i./A)
Lb/100
Gal (lb
a.i./100
gal)
Application Instructions
Gray Mold (Botrytis
cinerea)
Bulls-Eye Rot
(Neofabraea spp.)
harvest may provide better efficacy.
For resistance management, DO
NOT use a benzimidazole fungicide
post-harvest following Topsin 4.5FL
pre-harvest application.
Application of a non-benzimidazole
post-harvest fungicide will provide
additional protection from post-
harvest diseases.
Restrictions:
- DO NOT apply more than 1.0 lb/A
(0.7 lb ai/A) per application.
- DO NOT apply more than 4.0 lb of
product (2.8 lbs a.i.)/A/year.
-The minimum retreatment interval
is five (5) days.
- DO NOT apply more than five (5)
applications per year.
- DO NOT enter or allow worker
entry into treated areas during the
restricted entry interval (REI) of 2
days
-PHI: 1 day
Beans, dry
and succulent
Including:
Lima bean
Snap bean
Kidney bean
Mung bean
Navy bean
Pinto bean
Wax bean
Broad bean
Fava bean
Asparagus
bean
Blackeyed pea
Cowpea
Sweet lupine
White lupine
White Sweet
lupine
Grain lupine
Chick pea
White Mold
(Sclerotinia)
Gray Mold
(Botrytis)
Anthracnose
(Colletotrichum)
1½ - 2 lbs/A
(1.05 – 1.4)
OR
1 – 1½ lbs/A
(0.7 – 1.05)
For one application: Apply when
100% of plants have at least one
open bloom or when conditions are
favorable for disease development.
OR
For multiple applications: Make the
first application when 10% to 30%
of plants have at least one open
bloom and follow with sequential
applications on a 4- to 7-day
interval. Apply prior to the
development of disease for best
results.
Restrictions:
- DO NOT apply more than 2.0 lb/A
(1.4 lb ai/A) per application.
- DO NOT apply more than 4.0 lb of
product (2.8 lbs a.i.)/A/year.
-The minimum retreatment interval
is four (4) days.
- DO NOT apply more than five (5)
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17
Crop
Diseases
Lbs
product/
Acre (lb
a.i./A)
Lb/100
Gal (lb
a.i./100
gal)
Application Instructions
Garbanzo
bean
REI: 24 hours
for succulent
beans;
REI: 3 days
for dry beans.
applications per year.
- DO NOT enter or allow worker
entry into treated areas during the
restricted entry interval (REI) of 1
day for succulent beans.
- DO NOT enter or allow worker
entry into treated areas during the
restricted entry interval (REI) of 3
days for dry beans.
-PHI: California only, 14 days for
succulent beans, 28 days for dry
beans and lima beans.
-PHI: all other States, 14 days for
succulent beans and lima beans, 28
days for dry beans.
Canola,
Crambe
In North
Dakota,
Minnesota,
and Montana
(east of
Interstate 15
only)
White Mold
Sclerotinia Stem Rot
(Sclerotinia
sclerotiorum)
1-2 lbs/A
(0.7 – 1.4)
OR
1 lb/A
(0.7)
For one application: Apply at 20%
to 50% flowering for single
application.
OR
For multiple applications: Apply
with the first application at 20% to
30% flowering, and the second
application at 40% to 50%
flowering.
Thorough coverage of the flowers,
stems, and branches is essential for
control of White Mold.
Restrictions:
-DO NOT apply more than 2.0 lb/A
(1.4 lb ai/A) per application.
-DO NOT apply more than 2 lbs of
product (1.4 lbs a.i.)/A/year.
-DO NOT enter or allow worker
entry into treated areas during the
restricted entry interval (REI) of 1
day.
-PHI: 40 days
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18
Crop
Diseases
Lbs
product/
Acre (lb
a.i./A)
Lb/100
Gal (lb
a.i./100
gal)
Application Instructions
Cucurbits:
Cantaloupe,
Casaba,
Cucumbers,
Melons,
Pumpkins,
Summer and
Winter
Squash, and
Watermelon
Topsin M WSB can be used in a
tank mix with a protectant fungicide
including Manzate Pro-Stick (EPA
Reg. No. 70506-234, mancozeb),
Penncozeb (EPA Reg. No. 70506-
185, mancozeb), or Oranil 6L (EPA
Reg. No. 70506-262, chlorothalonil)
for additional disease control and
resistance management.
Restrictions:
- DO NOT apply more than 0.5 lb of
product (0.35 lb a.i./A) per
application.
- DO NOT apply more than 3.0 lbs
of product (2.1 lbs a.i.)/A/year from
any combination of application
timings.
-The minimum retreatment interval
is 4 days.
- DO NOT make more than 5
applications per year.
- DO NOT enter or allow worker
entry into treated areas during the
restricted
entry interval (REI) of 1 day.
- PHI: 1 day
Acremonium/
Cephalosporium
Hypocotyl Rot
½ lb/A
(0.5 lb)
Apply in-furrow, on top of the seeds
at planting.
Restriction:
DO NOT use less than 10 gallons of
water per acre.
Anthracnose*
(Colletotrichum)
Gummy Stem
Blight*
(Didymella)
Powdery Mildew
(Erysiphe,
Sphaerotheca,
Podosphaera)
Target Spot*
(Corynespora)
* Not for use in
California.
Begin applications when plants
begin to run or when disease first
appears and repeat at 7-14 day
intervals or as needed.
For Target Spot, use at 7-day
intervals as needed.
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19
Crop
Diseases
Lbs
product/
Acre (lb
a.i./A)
Lb/100
Gal (lb
a.i./100
gal)
Application Instructions
Belly Rots*
(Rhizoctonia,
Fusarium)
* Not for use in
California.
Apply in sufficient volume to allow
runoff to the soil. Will not control
Pythium or Phytophthora.
Suppresion of Vine
Decline
(Monosporascus)
Charcoal Rot
(Macrophomina)
Apply through buried drip
irrigation (chemigation) to the root
zone. Apply at 14-day
intervals, beginning at emergence
and continuing to harvest.
Applications weekly or biweekly,
beginning 4-6 weeks prior to
harvest will also offer
suppression, but may not be as
effective as a season-long
program.
Garlic
(clove
treatment)
Penicillium Clove
Rot
1 lb/100
gal.
(0.7)
Completely immerse garlic cloves in
suspension for at least 5 minutes.
Continuously agitate the solution
tank by hydraulic or mechanical
means.
After treatment, remove cloves from
solution and drain.
Dry cloves after treatment and prior
to planting.
Grapes
Restrictions:
- DO NOT apply more than 1.5 lbs
of product/A per application
-DO NOT apply more than 6 lbs of
product (4.2 lbs a.i.)/A/year.
-The minimum retreatment interval
is fourteen (14) days.
- DO NOT make more than four
applications per year.
- DO NOT enter or allow worker
entry into treated areas during the
restricted entry interval (REI) of 2
days.
-PHI: 7 days
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20
Crop
Diseases
Lbs
product/
Acre (lb
a.i./A)
Lb/100
Gal (lb
a.i./100
gal)
Application Instructions
WEST OF THE
ROCKY
MOUNTAINS:
Bunch Rot
(Botrytis)
Powdery Mildew
(Uncinula)
1 - 1½ lbs/A
(0.7 – 1.05)
Apply at first bloom and repeat 14
days later or as needed if severe
disease conditions exist. Make an
additional application 3 to 4 weeks
before harvest or when sugar begins
to build; repeat 14 days later if
conditions favorable for disease
persist.
For Powdery Mildew continue
applications through the season.
Use in combination or rotation with
a sulfur product including
Microthiol
® Disperss® (EPA Reg.
No. 70506-187, sulfur) and/or other
systemic fungicides.
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21
Crop
Diseases
Lbs
product/
Acre (lb
a.i./A)
Lb/100
Gal (lb
a.i./100
gal)
Application Instructions
Eutypa Dieback
Botryosphaeria
Paint-On
1 lb Topsin
M WSB (0.7
lb a.i.) per 5
gallons of
water; or 3.2
oz (2.24 oz
a.i.) per 1
gallon of
water
Paint-On Application: Apply as a
paint to cut or pruned surfaces
immediately after cutting and before
rain, dew, fog, and fungal spores
come into contact with fresh wood.
Results are improved by thorough
coverage of the pruning wounds and
by pruning at a time when little or
no rain is expected soon after
treatment. A second application may
be necessary within 2 weeks if
rainfall, fog, or high humidity persist
which slows pruning wound healing.
Spray
1.5 lbs/A
(1.05 lb a.i.)
in a
minimum of
50 gallons
of water
Spray-On Application: Apply as a
directed spray with power operated
ground application equipment to
thoroughly wet cordons, spurs, and
all cut wood surfaces within 24
hours of pruning. Topsin M WSB
may be tank-mixed with other
fungicides registered for protection
against this and similar grape canker
pathogens. The addition of a labeled
rate of an organosilicone, crop oil, or
other adjuvants which enhance
spreading and absorption may
increase penetration of cut wood
surfaces. The addition of a
registered dye to provide visual
confirmation of thorough coverage
of pruning wounds can be useful. A
second application may be necessary
within 2 weeks if rainfall, fog, or
high humidity persist which slows
pruning wound healing.
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22
Crop
Diseases
Lbs
product/
Acre (lb
a.i./A)
Lb/100
Gal (lb
a.i./100
gal)
Application Instructions
EAST OF THE
ROCKY
MOUNTAINS:
Bitter Rot
(Melanconium)
Black Rot
(Guignardia)
Powdery Mildew
(Uncinula)
Phomopsis Cane and
Leaf Spot
(Phomopsis)
¾ - 1½
lbs/A
(0.53 – 1.05)
Apply when foliage first develops
and repeat at 14 to 21-day intervals
or as needed.
Bunch Rot
(Botrytis)
1 - 1½ lbs/A
(0.7 – 1.05)
Apply at first bloom and repeat 14
days later or as needed if severe
disease conditions exist. Make an
additional application 3 to 4 weeks
before harvest or when sugar begins
to build; repeat 14 days later if
conditions favorable for disease
persist.
DO NOT use where resistant strains
of Botrytis are present.
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23
Crop
Diseases
Lbs
product/
Acre (lb
a.i./A)
Lb/100
Gal (lb
a.i./100
gal)
Application Instructions
Eutypa Dieback
Botryosphaeria
Paint-On 1lb
Topsin M
WSB (0.7 lb
a.i.) per 5
gallons of
water; or 3.2
oz
(2.24 oz a.i.)
per 1 gallon
of water
Paint-On Application: Apply as a
paint to cut or pruned surfaces
immediately after cutting and before
rain, dew, fog, and fungal spores
come into contact with fresh wood.
Results are improved by thorough
coverage of the pruning wounds and
by pruning at a time when little or
no rain is expected soon after
treatment. A second application may
be necessary within 2 weeks if
rainfall, fog, or high humidity persist
which slows pruning wound healing.
Spray
1.5 lbs/A
(1.05 lb a.i.)
in a
minimum of
30 gallons
of water
Spray-On Application: Apply as a
directed spray with power operated
ground application equipment to
thoroughly wet cordons, spurs, and
all cut wood surfaces within 24
hours of pruning. Topsin M WSB
may be tank-mixed with other
fungicides registered for protection
against this and similar grape canker
pathogens. The addition of a labeled
rate of an organosilicone, crop oil, or
other adjuvants which enhance
spreading and absorption may
increase penetration of cut wood
surfaces. The addition of a
registered dye to provide visual
confirmation of thorough coverage
of pruning wounds can be useful. A
second application may be necessary
within 2 weeks if rainfall, fog, or
high humidity persist which slows
pruning wound healing.
Onions*
Garlic
(In furrow)
* Not for use
in California.
White Rot
(Sclerotium
cepivorum)
2 lbs/A
(1.4 lb a.i.)
Broadcast
equivalent
Spray directly into the open furrow
at the time of planting seed, sets or
bulbs.
Restrictions:
-Not for this use through any type of
irrigation system.
- DO NOT apply more than 2.0 lbs
of product (1.4 lbs a.i.) per
application.
- DO NOT make more than one
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24
Crop
Diseases
Lbs
product/
Acre (lb
a.i./A)
Lb/100
Gal (lb
a.i./100
gal)
Application Instructions
application per year.
- DO NOT apply more than 2.0 lbs
of product (1.4 lbs a.i.)/A/year.
- DO NOT enter or allow worker
entry into treated areas during the
restricted
entry interval (REI) of 3 days.
Peanuts
Early Leaf Spot
(Cercospora)
Late Leaf Spot
(Cercsoporidium)
Rust (Puccinia)
Limb Rot
(Rhizoctonia)
Web Blotch
(Ascochyta)
½ lb/A
(0.35)
Begin applications when disease
first appears and repeat at 14-day
intervals as needed.
Restrictions:
- DO NOT apply more than 0.5 lb
of product (0.35 lbs a.i.) per
application.
- DO NOT apply more than 2.0 lbs
of product (1.4 lbs a.i.)/A/year.
-The minimum retreatment interval
is 14 days.
- DO NOT apply more than 4
applications per year.
-Topsin M WSB should not be used
alone. Use only in combination with
a non-benzimidazole fungicide
including Manzate Pro-Stick (EPA
Reg. No. 70506-234, mancozeb),
Penncozeb (EPA Reg. No. 70506-
185, mancozeb), or Oranil 6L (EPA
Reg. No. 70506-262, chlorothalonil)
- DO NOT enter or allow worker
entry into treated areas during the
restricted entry interval (REI) of 1
day.
-PHI: 14 days
Pears
Pear Scab
(Venturia)
Sooty Blotch
(Gloeodes)
1 lb/A
(0.7)
¼
lb/100
gal.
(0.18)
Apply at 5 to 10-day intervals from
green tip through petal fall; continue
at 7 to 14-day intervals in the cover
sprays.
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Page 25 of 41
25
Crop
Diseases
Lbs
product/
Acre (lb
a.i./A)
Lb/100
Gal (lb
a.i./100
gal)
Application Instructions
Flyspeck
(Zygophiala)
Powdery Mildew
(Podosphaera)
Leaf Spot
(Fabraea)
Restrictions:
- DO NOT apply more than 1.0 lb/A
(0.7 lb ai/A) per application.
- DO NOT apply more than 4.0 lb of
product (2.8 lbs a.i.)/A/year.
-The minimum retreatment interval
is five (5) days.
- DO NOT apply more than four (4)
applications per year.
- DO NOT enter or allow worker
entry into treated areas during the
restricted entry interval (REI) of 2
days
-PHI: 1 day
Use to control Development of Diseases on Pears Following Harvest
Storage Rot
Blue Mold
(Penicillium
expansum)
Gray Mold (Botrytis
cinerea)
Bulls-Eye Rot
(Neofabraea spp.)
1 lb/A
(0.7)
Apply as a pre-harvest spray within
2 weeks to 3 days of harvest.
Thorough coverage of the fruit is
required. Application closer to
harvest may provide better efficacy.
For resistance management, DO
NOT use a benzimidazole fungicide
post-harvest following Topsin M
WSB pre-harvest application.
Application of a non-benzimidazole
post-harvest fungicide will provide
additional protection from post-
harvest diseases.
Restrictions:
-DO NOT apply more than 4 lbs of
product (2.8 lbs a.i.)/A/year.
-DO NOT apply more than 1.0 lb/A
(0.7 lb ai/A) per application.
-DO NOT apply more than four (4)
applications per year.
-The minimum retreatment interval
is 7 days.
-DO NOT enter or allow worker
entry into treated areas during the
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Page 26 of 41
26
Crop
Diseases
Lbs
product/
Acre (lb
a.i./A)
Lb/100
Gal (lb
a.i./100
gal)
Application Instructions
restricted entry interval (REI) of 2
days
-PHI: 1 day
Pecans
Brown Spot
(Cercospora)
Downy Spot
(Mycosphaerella)
Liver Spot
(Gnomonia)
Powdery Mildew
(Microsphaera)
Scab
(Fusicladium)
Stem End Blight
(Botryosphaeria)
Zonate Leaf Spot
(Cristulariella)
1 lb/A
(0.7)
Begin applications when first leaves
are showing and repeat at 3- to 4-
week intervals until shuck split.
Restrictions:
-DO NOT apply after shuck split.
-DO NOT apply more than 1.0 lb/A
(0.7 lb ai/A) per application.
-DO NOT apply more than 3 lbs of
product (2.1 lbs a.i.)/A/year.
-The minimum retreatment interval
is 21 days.
-DO NOT make more than three
applications per year.
-DO NOT enter or allow worker
entry into treated areas during the
restricted entry interval (REI) of 3
days.
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Label Updates and Mitigation Additions
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27
Crop
Diseases
Lbs
product/
Acre (lb
a.i./A)
Lb/100
Gal (lb
a.i./100
gal)
Application Instructions
Pistachios
Shoot Blight
(Botrytis,
Botryosphaeria)
1½ - 2 lbs/A
(1.05 – 1.4)
Apply at bloom.
Apply in a minimum of 100 gallons
per acre by ground or 20 gallons per
acre by air.
For aerial application, fly over every
row or center
Restrictions:
- DO NOT apply more than 2.0
lbs/A (1.4 lb. a.i./A) per application.
- DO NOT apply more than 2.0 lbs
of product (1.4 lbs a.i.)/A/year.
- DO NOT apply more than one (1)
application per year.
- DO NOT enter or allow worker
entry into treated areas during the
restricted entry interval (REI) of 3
days.
Potatoes
White Mold
(Sclerotinia
sclerotiorum)
1 - 1½ lb/A
(0.7 – 1.05)
Make first application just prior to
row closure. Repeat the application
within 7-14 days and at 7-14 day
intervals if conditions for disease
development are favorable.
Thorough coverage of the flowers,
stems, and branches is essential for
disease control.
Use a minimum of 6 gallons/A of
water for aerial application.
Apply prior to the development of
disease for optimal results.
May be tank mixed with Manzate
Pro-Stick (EPA Reg. No. 70506-
234, mancozeb) or Penncozeb (EPA
Reg. No. 70506-185, mancozeb) for
early and late blight control.
Restrictions:
- DO NOT apply more than 1.5
lbs/A (1.05 lb. a.i./A) per
application.
- DO NOT apply more than 4.0 lbs
of product (2.8 lbs a.i.)/A/year.
-The minimum retreatment interval
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Label Updates and Mitigation Additions
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28
Crop
Diseases
Lbs
product/
Acre (lb
a.i./A)
Lb/100
Gal (lb
a.i./100
gal)
Application Instructions
is seven (7) days.
- DO NOT apply more than four (4)
applications per year.
- DO NOT enter or allow worker
entry into treated areas during the
restricted
entry interval (REI) of 2 days.
-Pre-harvest interval: 21 days
Soybeans
Restrictions:
-DO NOT apply more than 2.0 lbs
of product/A (1.4 lb. a.i./A) for a
single application for white mold
control otherwise DO NOT apply
more than 1.0 lb of product/A (0.7
lb. a.i./A) for a single application.
-DO NOT apply more than 2.0 lbs.
of product (1.4 lbs a.i.)/A/year.
-The minimum retreatment interval
is seven (7) days.
-DO NOT apply more than two (2)
applications per year.
-DO NOT enter or allow worker
entry into treated areas during the
restricted entry interval (REI) of 1
day.
-Pre-harvest interval: 21 days
-DO NOT graze or feed treated
vines or hay to livestock.
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29
Crop
Diseases
Lbs
product/
Acre (lb
a.i./A)
Lb/100
Gal (lb
a.i./100
gal)
Application Instructions
Anthracnose
(Colletotrichum)
Brown Spot
(Septoria)
Frogeye Leaf Spot
(Cercospora)
Pod and Stem Blight
(Diaporthe,
Phomopsis)
Purple Seed Stain
(Cercospora)
½ - 1 lbs/A
(0.35 – 0.7)
Apply from full bloom to when pods
DUHǩ
WRó
LQOHQJWK0DNHD
second application 14 to 21 days
later. DO NOT make the second
application later than 14 days after
pods average ¼'' in length or when
beans form in the pod. Use the high
rate under severe disease pressure.
1 lb/A
(0.7)
FOR SEED BEANS ONLY---For
seed quality, make a single
application when beans form in the
pod.
White Mold
(Sclerotinia)
1 lb/A
(0.7)
OR
2 lbs/A
(1.4)
For split applications, apply initial
application of 1 lb/A at early bloom
(R-1 stage). Follow with a second
application 7-14 days later.
OR
For single application, apply 2 lbs/A
at early bloom (R-1 stage).
Thorough coverage of the flowers,
stems, and branches is essential for
disease control.
Use a minimum of 5 gallons water/A
by air.
Aerial Blight
(suppression)
1 lb/A
(0.7)
Make initial application when
disease threatens and repeat 14-21
days later if needed.
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30
Crop
Diseases
Lbs
product/
Acre (lb
a.i./A)
Lb/100
Gal (lb
a.i./100
gal)
Application Instructions
Stone Fruit
Restrictions:
- DO NOT apply more than 1.5 lbs
of product/A (1.05 lb. a.i./A) per
application.
- DO NOT apply more than 4.0 lbs
of product (2.8 lbs a.i.)/A/year.
-The minimum retreatment interval
is ten (10) days.
- DO NOT make more than four (4)
applications per year.
- DO NOT enter or allow worker
entry into treated areas during the
restricted
entry interval (REI) of 2 days.
-Pre-harvest interval: 1 day
- Apricots
Brown Rot Blossom
Blight
Fruit Brown Rot
(Monilinia)
1 - 1½ lbs/A
(0.7 – 1.05)
(In
California 1
½ lbs/A
(1.05))
ѿ- ½
lbs/100
gal.
(0.23 –
0.35)
Apply at early bloom (red bud).
Make a second application at full
bloom.
If needed, under severe disease
pressure, apply additional sprays at
10 to 14-day intervals between full
bloom and final pre-harvest sprays.
- Cherries
Sweet and
Sour
Brown Rot Blossom
Blight
European Brown Rot
Fruit Brown Rot
(Monilinia)
1 - 1½
(0.7 – 1.05)
(in CA use
1½ (1.05))
ѿ- ½
lbs/100
gal.
(0.23 –
0.35)
Apply at early bloom (early
popcorn). Make a second application
at full bloom.
If needed under severe disease
pressure, apply additional sprays at
10 to 14-day intervals between full
bloom and final pre-harvest sprays.
Cherry Leaf Spot
(Coccomyces)
ǩ- 1½
(0.8 – 1.05)
Ǫ- ½
lbs/100
gal.
(0.26 –
0.35)
Applications may be made at petal
fall or before (when leaves first
unfold) and at first, second, and third
cover at 10 to 14-day intervals and
one spray 14 to 21 days after
harvest.
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31
Crop
Diseases
Lbs
product/
Acre (lb
a.i./A)
Lb/100
Gal (lb
a.i./100
gal)
Application Instructions
Powdery Mildew
(Podosphaera,
Sphaerotheca)
1 - 1½ lbs/A
(0.7 – 1.05)
(In
California
use 1 ½
lbs/A (1.05))
PLUS
ǩ- 1½
lbs/A (0.8 –
1.05)
ѿ- ½
lbs/100
gal.
(0.23 –
0.35)
PLUS
Ǫ- ½
lbs/100
gal.
(0.26 –
0.35)
Apply at early bloom (early
popcorn). Make a second application
at full bloom.
PLUS
Apply at shuck fall and first cover.
- Nectarines
Brown Rot Blossom
Blight
Fruit Brown Rot
(Monilinia)
1 - 1½ lbs/A
(0.7 – 1.05)
(In
California
use 1 ½
lbs/A (1.05))
ѿ- ½
lbs/100
gal.
(0.23 –
0.35)
Apply at early bloom (pink bud).
Make a second application at full
bloom if conditions favor disease
development.
If needed under severe disease
pressure, apply additional sprays at
10 to 14-day intervals between full
bloom and final pre-harvest sprays.
- Peaches
Brown Rot Blossom
Blight
Fruit Brown Rot
(Monilinia)
1 - 1½ lbs/A
(0.7 – 1.05)
(In
California
use 1 ½
lbs/A (1.05))
ѿ- ½
lbs/100
gal.
0.23 –
0.35)
Apply at early bloom (pink bud).
Make a second application at full
bloom if conditions favor disease
development.
If needed under severe disease
pressure, apply additional sprays at
10 to 14-day intervals between full
bloom and final pre-harvest sprays.
Peach Scab
(Cladosporium)
1 - 1½ lbs/A
(0.7 – 1.05)
(In
California
use 1 ½
lbs/A (1.05))
PLUS
ǩ- 1½
lbs/A (0.8 –
1.05)
ѿ- ½
lbs/100
gal.
(0.23 –
0.35)
PLUS
Ǫ- ½
lbs/100
gal
(0.26 –
0.35)
Apply at early bloom (pink bud).
Make a second application at full
bloom if conditions favor disease
development.
PLUS
Apply at shuck split and at first
cover sprays.
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32
Crop
Diseases
Lbs
product/
Acre (lb
a.i./A)
Lb/100
Gal (lb
a.i./100
gal)
Application Instructions
- Plums
and Prunes
Brown Rot Blossom
Blight
Fruit Brown Rot
(Monilinia)
1 - 1½ lbs/A
(0.7 – 1.05)
(In
California
use 1 ½
lbs/A (1.05))
ѿ- ½
lbs/100
gal.
(0.23 –
0.35)
Apply at early bloom (green tip).
Make a second application at full
bloom.
If needed under severe disease
pressure, apply additional sprays at
10 to 14-day intervals between full
bloom and final pre-harvest sprays.
Black Knot
(Dibotryon)
Apply at pre-bloom, petal fall, and at
first, second, or third cover sprays at
10 to 14-day intervals.
Leaf Spot
(Coccomyces)
Applications may be made at petal
fall, shuck split, and at first, second,
and third cover sprays at 10 to
14-day intervals and 1 spray 14 to 21
days after harvest.
Strawberries
Restrictions:
- DO NOT apply more than 1.0 lb of
product/A (0.7 lb. a.i./A) per
application.
- DO NOT apply more than 4.0 lbs
of product (2.8 lbs a.i.)/A/year.
-The minimum retreatment interval
is seven (7) days.
- DO NOT apply more than 4
applications per year.
- DO NOT enter or allow worker
entry into treated areas during the
restricted entry interval (REI) of 1
day.
-Pre-harvest interval: 1 day
Crown Rot*
(Colletotrichum
spp.)
Suppression only
* Not for use in
California.
¾ - 1 lbs/A
(0.53 – 0.7)
Begin applications after
establishment of the transplants and
continue through first bloom at 10 to
14-day intervals. Use the high rate
if the fields have a history of
Colletotrichum crown rot and/or
conditions are favorable for
development of the disease. Will
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33
Crop
Diseases
Lbs
product/
Acre (lb
a.i./A)
Lb/100
Gal (lb
a.i./100
gal)
Application Instructions
not control Phytophthora species.
Fruit Rot
(Botrytis)
Leaf Blight
(Dendrophoma)
Leaf Scorch
(Diplocarpon)
Powdery Mildew
(Sphaerotheca)
Begin applications at early bloom
and continue at 7 to 10-day intervals.
Use the higher rate under conditions
of severe disease pressure.
Charcoal Rot
(Macrophomina)
1 lb/A
(0.7)
Apply through buried drip irrigation
(chemigation) to the root zone.
Apply at 14-day intervals beginning
at transplant.
Sugar Beets
Restrictions:
- DO NOT apply more than 1.0 lb of
product/A (0.7 lb. a.i./A) per
application.
- DO NOT apply more than 3.0 lbs
of product (2.1 lbs a.i.)/A/year.
-The minimum retreatment interval
is fourteen (14) days.
- DO NOT apply more than 3
applications per year.
- DO NOT enter or allow worker
entry into treated areas during the
restricted entry interval (REI) of 1
day.
-Pre-harvest interval: 21 days
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34
Crop
Diseases
Lbs
product/
Acre (lb
a.i./A)
Lb/100
Gal (lb
a.i./100
gal)
Application Instructions
Cercospora Leaf
Spot (Cercospora)
½ - 1 lb/A
Apply when conditions become
favorable for disease development
before the disease appears and
follow with a non-benzimidazole
fungicide within 14 days of
application or as needed. Topsin M
WSB should be tank mixed with a
protectant fungicide including
Manzate Pro-Stick (EPA Reg. No.
70506-234, mancozeb), Penncozeb
(EPA Reg. No. 70506-185,
mancozeb) or Super Tin 4L (EPA
Reg. No. 70506-212, triphenyltin
hydroxide) when resistant strains of
Cercospora are present in the field.
For areas east of the Rocky
Mountans: DO NOT make more
than one application of Topsin M
WSB per season for Cercospora
Leaf Spot.
Powdery Mildew
(Erysiphe)
Apply as soon as disease symptoms
appear and follow with a non-
benzimidazole fungicide at a 14-day
interval or as needed. Topsin M
WSB can be tank mixed with sulfur
products including Microthiol
Disperss (EPA Reg. No. 70506-187,
sulfur) at 5 to 10 lbs/A for additional
disease control and resistance
management.
Triticale and
Fall-seeded
Wheat
For this use
in Idaho,
Oregon, and
Washington
ONLY
Foot Rot,
Strawbreaker,
Eye Spot
(Pseudocercosporella
)
1 lb/A
(0.7)
Apply in a single application by air
or ground after tillering but before
stem elongation has begun. Use
sufficient water to obtain thorough
coverage.
Restrictions:
- DO NOT apply more than 1.0 lb of
product (0.7 lb a.i./A) per
application.
- DO NOT apply more than 1.0 lb of
product (0.7 lb a.i.)/A/year.
- DO NOT enter or allow worker
entry into treated areas during the
restricted entry interval (REI) of 24
hours.
- DO NOT cut for hay within 90
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35
Crop
Diseases
Lbs
product/
Acre (lb
a.i./A)
Lb/100
Gal (lb
a.i./100
gal)
Application Instructions
days of application.
- DO NOT allow livestock to graze
in treated areas before harvest.
NOTE: Dilute sprays are not to exceed maximum rate per acre.
DIRECTIONS FOR USE
In the Aid in Control of Certain Canker Diseases Following Pruning of Almonds, Apricots,
Cherries, Grapes, Nectarines, Peaches, Plums and Prunes.
To protect pruning cuts from canker diseases caused by fungal pathogens including
Botryosphaeria spp. Eutypa lata, Leucostoma persoonii (Cytospora), Calosphaeria
pulchella, Lasiodiplodia theobromae, and Diaporthe neotheicola (Phomopsis) apply Topsin
M WSB fungicide in spray or paint-on to pruning wounds.
Spray: Apply Topsin M WSB at 1.5 lbs per acre (1.05 lb a.i.) in a minimum of 30 gallons alone,
or a minimum of 50 gallons when tank mixed per acre, using power operated ground application
equipment or a backpack sprayer. If backpack sprayer is used, chemical-resistant coveralls or a
chemical-resistant coat must be worn.
Paint-on: Apply Topsin M WSB at 3.2 oz (2.24 oz a.i.) per 1 gallon water (1lb (0.7 lb a.i.) per 5
gallons of water) as a paint to cut or pruned surfaces immediately after cutting and before rain,
dew, fog and fungal spores come into contact with fresh wood.
Results are improved by thorough coverage of pruning wounds and by pruning at a time when
little or no rain is expected soon after treatment.
For improved management of canker diseases by fungal pathogens and for fungicide resistance
management, it is directed to apply Topsin M WSB in a tank-mix with Rally® 40WSP (EPA
Reg. No. 62719-410, myclobutanil) at 5 oz per acre for grapes and at 6 oz/acre for almonds,
apricots, cherries, nectarines, peaches, plums and prunes and/or in the tank mix with other
fungicides registered for canker disease management. Refer to the Rally 40 WSP
(EPA Reg. No.
62719-410, myclobutanil) Special 2(ee) Recommendation for further information on this use.
Protect pruning cuts as soon as possible especially if irrigation, rainfall or fog is expected.
Application within 24 hours is highly advised. Applications after 24 hours are permitted, but
disease control may be reduced. Assure thorough coverage of all cut wood surfaces. For these
pathogens, multiple applications may be needed. Make additional applications at approximately
two-week intervals, especially if irrigation, rainfall or high humidity conditions exist.
The addition of a labeled rate of a registered organo-silicone spray adjuvant may increase
penetration of cut wood surfaces. It is the responsibility of the user to assure that the organo-
silicone spray adjuvant is safe to the crop under the existing conditions of use and label on the
adjuvant container. Addition of a registered spray dye to the tank mix, and visual inspection of
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36
the pruning cuts after application, will help assure thorough coverage of susceptible tissue.
Specific Use Restrictions:
Crop Maximum Use Rate Per Acre
Per Year
REI
Almonds 3 lbs (2.1 lbs ai)/A/Year 3 days
Grapes 6 lbs (4.2 lbs ai)/A/Year 2 days
Apricots, Cherries,
Nectarines, Peaches, Plums
and Prunes
4 lbs (2.8 lbs ai)/A/Year 2 days
DIRECTIONS FOR USE ON CONIFERS
(Not for this use in California)
Conifers foliar treatment
CROP
DISEASE
RATE (Lb/A),
Minimum
Gallonage
APPLICATION
INSTRUCTIONS
Conifers (Pine)
Austrian
Red
Scots
Christmas Trees
Tip Blight
(Diplodia)
1 lb./A (0.7 lb
a.i.) per
100 gal/A
Apply at bud break.
Repeat 10 to 14 days later,
just before needles emerge
from sheath; repeat again
10 to 14 days after needle
emergence.
Restrictions:
- DO NOT apply more
than 60 fl. oz. of product
(2.1 lbs. a.i.)/A/year.
-The minimum
retreatment interval is ten
(10) days.
- DO NOT apply more
than 3 applications per
year.
- DO NOT enter or allow
worker entry into treated
areas during the restricted
entry interval (REI) of 12
hours.
- DO NOT graze livestock
in treated areas.
(Fir)
Douglas
Swiss Needle Cast
(Phaecryptopus)
Rhabdocline Needle Cast
1 lb./A (0.7 lb
a.i.) per
50 gal/A
Apply initially in early
May. Repeat at 4-week
intervals.
Add a spreader/sticker to
improve coverage.
Use minimum gallonage
with mist-blower types of
sprayers and higher
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37
gallonage with
conventional sprayers.
DO NOT apply more than
5 lbs. of product (3.5 lbs.
a.i.)/A/year.
Conifers Seedling Treatment
Conifers
Longleaf
Brown Needle Blight
(Scirrhia)
1 oz. product (0.7
oz a.i.) per 9.5
oz. dry Kaolinite
clay for seedling
roots
Wet seedling roots in
clean water, then dip roots
into Topsin M WSB
/Kaolinite mixture.
Loblolly
Longleaf
Slash
Fusarium and Rhizoctonia
Root Rot
2 oz. product (1.4
oz a.i.) per 50 oz.
Kaolinite clay,
plus enough
water to make a
slurry
Dip seedling roots into
Topsin M WSB /Kaolinite
slurry.
Restrictions for Seedling Treatment:
-DO NOT apply mixture to seedling foliage
- During treatment, avoid excessive drying of roots or exposure to temperatures greater than 90°F or
less than 32°F.
- DO NOT enter or allow workers to enter into treated areas during the restricted entry interval (REI)
of 12 hours.
- Note: Topsin M WSB does not control Pythium or Phytophthora.
DIRECTIONS FOR USE THROUGH CHEMIGATION SYSTEMS
USE IN CALIFORNIA BY CHEMIGATION ONLY FOR BEANS, CUCURBITS
(CANTALOUPE, CASABA, CUCUMBERS, MELONS, PUMPKINS, SQUASH,
WATERMELONS), PEANUTS, POTATOES, SOYBEANS, STRAWBERRlES, AND SUGAR
BEETS.
PRODUCT INSTRUCTIONS
Apply this product only through sprinkler irrigation systems including center pivot, lateral move,
end tow, side (wheel) roll, traveler, solid set or hand move; or drip (mini-micro sprinklers, strip
tubing, trickle) irrigation systems. DO NOT apply this product through any other type of
irrigation system.
Crop injury, lack of effectiveness, or illegal pesticide residues in the crop can result from
nonuniform distribution of treated water.
If you have any questions about calibration, you should contact State Extension Service
specialists, equipment manufacturers or other experts.
A person knowledgeable of the chemigation system and responsible for its operation, or under
the supervision of the responsible person, shall shut the system down and make necessary
adjustments should the need arise.
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38
DO NOT connect chemigation system to any public water system. Public water system means a
system for the provision of piped water for human consumption if such a system has at least 15
service connections or regularly serves an average of at least 25 individuals daily at least 60 days
out of the year.
SYSTEM REQUIREMENTS
Systems utilizing a pressurized water and pesticide injection system must meet the following
requirements:
The system must contain a functional check valve, vacuum relief valve, and low pressure drain
appropriately located on the irrigation pipeline to prevent water source contamination from
backflow.
The pesticide injection pipeline must contain a functional, automatic, quick-closing check valve
to prevent the flow of fluid back toward the injection pump. The pesticide injection pipeline must
also contain a functional, normally closed, solenoid-operated valve located on the intake side of
the injection pump and connected to the system interlock to prevent fluid from being withdrawn
from the supply tank when the irrigation system is either automatically or manually shut down.
The system must contain functional interlocking controls to automatically shut off the pesticide
injection pump when the water pump motor stops.
The irrigation line or water pump must include a functional pressure switch that will stop the
water pump motor when the water pressure decreases to the point where pesticide distribution is
adversely affected.
Systems must use a metering pump, for example a positive displacement injection pump (e.g.,
diaphragm pump) effectively designed and constructed of materials that are compatible with
pesticides and capable of being fitted with a system interlock.
APPLICATION INSTRUCTIONS FOR CHEMIGATION SYSTEMS
Observe the requirements in the System Requirements section above.
Apply Topsin M WSB only through systems containing anti-syphon and check valves designed
to prevent water source contamination or overflow of the mix tank and containing interlocking
controls between the metering device and the water pump to insure simultaneous shut-off.
Maintain a gentle continuous agitation in mix tank during mixing and application to assure a
uniform suspension.
Greater accuracy in calibration and distribution will be achieved by injecting a larger volume of
a more dilute suspension per unit time.
Application of more than specified quantities of irrigation water per acre may result in decreased
product performance.
DO NOT apply when wind speed favors drift, when system connections or fittings leak, when
nozzles do not provide uniform distribution or when lines containing the product cannot be
flushed and must be dismantled and drained. In a center pivot system, block the nozzle set
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nearest the well/pivot/injection unit to prevent spray being applied to this area.
Where sprinkler distribution patterns do not overlap sufficiently, unacceptable disease control
may result.
Allow sufficient time for pesticide to be flushed through all lines and all nozzles before turning
off irrigation water.
Topsin M WSB may be applied in conjunction with chemically neutral liquid fertilizers.
Application in conjunction with highly alkaline fertilizers, for example aqueous ammonia, may
cause a degradation of the pesticide, resulting in reduced performance and should be avoided.
SPRAY PREPARATION:
Remove scale, pesticide residues, and other foreign matter from the chemical tank and entire
injector system. Flush with clean water.
Prepare a suspension of Topsin M WSB in a mix tank. Fill the tank with ½ or ¾ of the desired
amount of water. Start mechanical or hydraulic agitation. Slowly add the required amount of
Topsin M WSB and then the remaining volume of water.
Sprinkler Irrigation
Observe all System Requirements and Application Instructions above.
Set sprinkler system to deliver a maximum of 0.4 inch of water per acre. Volumes of water
higher than this may reduce efficacy. Start sprinkler and then uniformly inject the suspension of
Topsin M WSB into the irrigation water line so as to deliver the desired rate per acre. The
suspension of Topsin M WSB should be injected with a positive displacement pump into the
main line ahead of a right angle turn to insure adequate mixing. When treatment with Topsin M
WSB has been completed, DO NOT irrigate the treated area for 24 to 48 hours to prevent
washing the chemical off the crop.
DO NOT apply when wind speed favors drift beyond the area intended for treatment.
Where sprinkler distributed patterns do not overlap sufficiently, unacceptable disease control
may result.
Check local restrictions and requirements regarding sprinkler irrigation applications, as they may
vary from state to state.
Drip (Mini-Micro Sprinklers, Strip Tubing, Trickle) Irrigation
Observe all System Requirements and Application Instructions above.
A pesticide supply tank is advised.
STORAGE AND DISPOSAL
DO NOT contaminate water, food, or feed by storage or disposal.
STORAGE: Store in the original container in a dry area. DO NOT store in a manner where
cross-contamination with other pesticides, fertilizers, food or feed could occur. If spilled during
storage or handling, sweep up spillage and dispose of in accordance with the Pesticide Disposal
Instructions listed below.
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PESTICIDE DISPOSAL: Pesticide wastes are toxic. Improper disposal of excess pesticide,
spray mixture, or rinsate is a violation of Federal Law. If these wastes cannot be disposed of by
use according to label instructions, contact your State Pesticide or Environmental Control
Agency, or the Hazardous Waste representative at the nearest EPA Regional Office for guidance.
CONTAINER HANDLING:
Nonrefillable container. DO NOT reuse or refill this container. Offer for recycling, if available
or dispose of the empty outer foil pouch in the trash as long as the WSP is unbroken.
EMERGENCY TELEPHONE NUMBERS:
CHEMTREC: (800) 424-9300
MEDICAL: (866) 767-5089 Rocky Mountain Poison Control Center
IMPORTANT INFORMATION
READ BEFORE USING PRODUCT
CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY
NOTICE: Read the entire Directions for Use and Conditions of Sale and Limitation of
Warranty and Liability before buying or using this product. If the terms are not acceptable,
return the product at once, unopened, and the purchase price will be refunded.
The Directions for Use of this product reflect the opinion of experts based on field use and tests
and must be followed carefully. It is impossible to eliminate all risks associated with the use of
this product. Crop injury, ineffectiveness or other unintended consequences may result because
of such factors as manner of use or application, weather or crop conditions, presence of other
materials or other influencing factors in the use of the product, which are beyond the control of
Nippon Soda Co., Ltd. or Seller. Handling, storage, and use of the product by Buyer or User are
beyond the control of Nippon Soda Co., Ltd. and Seller. All such risks shall be assumed by
Buyer and User, and Buyer and User agree to hold Nippon Soda Co., Ltd. and Seller harmless
for any claims relating to such factors.
TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, NIPPON SODA CO., LTD.
AND SELLER MAKE NO WARRANTIES OF MERCHANTABILITY OR OF FITNESS FOR
A PARTICULAR PURPOSE NOR ANY OTHER EXPRESS OR IMPLIED WARRANTY
EXCEPT AS STATED ON THIS LABEL.
To the extent consistent with applicable law, Nippon Soda Co., Ltd. or Seller shall not be liable
for any incidental, consequential or special damages resulting from the use or handling of this
product and THE EXCLUSIVE REMEDY OF THE USER OR BUYER, AND THE
EXCLUSIVE LIABILITY OF NIPPON SODA CO., LTD. AND SELLER FOR ANY AND
ALL CLAIMS, LOSSES, INJURIES OR DAMAGES (INCLUDING CLAIMS BASED ON
BREACH OF WARRANTY, CONTRACT, NEGLIGENCE, TORT, STRICT LIABILITY
OR OTHERWISE) RESULTING FROM THE USE OR HANDLING OF THIS
PRODUCT, SHALL BE THE RETURN OF THE PURCHASE PRICE OF THE
PRODUCT OR, AT THE ELECTION OF NIPPON SODA CO., LTD. OR SELLER, THE
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41
REPLACEMENT OF THE PRODUCT.
Nippon Soda Co., Ltd. and Seller offer this product, and Buyer and User accept it, subject to the
foregoing conditions of sale and limitations of warranty and of liability, which may not be
modified except by written agreement signed by the duly authorized representative of Nippon
Soda Co., Ltd.
Topsin is a registered trademark of Nippon Soda Company, Ltd.
Penncozeb, Microthiol, and Disperss are registered trademarks of United Phosphorus, Inc.
Rev. 2/14/25